Amino acid dipepetide frequency for Hubei permutotetra-like virus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.494AlaAla: 3.494 ± 0.739
0.582AlaCys: 0.582 ± 0.803
2.912AlaAsp: 2.912 ± 1.791
2.912AlaGlu: 2.912 ± 0.68
1.165AlaPhe: 1.165 ± 0.617
3.494AlaGly: 3.494 ± 0.372
0.582AlaHis: 0.582 ± 0.308
2.912AlaIle: 2.912 ± 0.431
4.659AlaLys: 4.659 ± 0.866
4.077AlaLeu: 4.077 ± 1.047
0.0AlaMet: 0.0 ± 0.0
2.912AlaAsn: 2.912 ± 0.68
0.582AlaPro: 0.582 ± 0.308
2.33AlaGln: 2.33 ± 1.233
4.659AlaArg: 4.659 ± 0.866
3.494AlaSer: 3.494 ± 0.372
3.494AlaThr: 3.494 ± 0.372
6.407AlaVal: 6.407 ± 1.052
0.582AlaTrp: 0.582 ± 0.308
3.494AlaTyr: 3.494 ± 2.594
0.0AlaXaa: 0.0 ± 0.0
Cys
0.582CysAla: 0.582 ± 0.308
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.582CysGlu: 0.582 ± 0.308
0.582CysPhe: 0.582 ± 0.308
1.747CysGly: 1.747 ± 0.925
0.0CysHis: 0.0 ± 0.0
0.582CysIle: 0.582 ± 0.803
0.582CysLys: 0.582 ± 0.308
1.747CysLeu: 1.747 ± 0.186
0.582CysMet: 0.582 ± 0.308
0.582CysAsn: 0.582 ± 0.803
0.0CysPro: 0.0 ± 0.0
1.165CysGln: 1.165 ± 0.494
0.582CysArg: 0.582 ± 0.308
1.165CysSer: 1.165 ± 0.494
0.0CysThr: 0.0 ± 0.0
0.582CysVal: 0.582 ± 0.308
0.0CysTrp: 0.0 ± 0.0
1.165CysTyr: 1.165 ± 0.617
0.0CysXaa: 0.0 ± 0.0
Asp
4.659AspAla: 4.659 ± 0.245
0.582AspCys: 0.582 ± 0.803
2.33AspAsp: 2.33 ± 0.122
2.912AspGlu: 2.912 ± 0.68
2.912AspPhe: 2.912 ± 1.542
5.242AspGly: 5.242 ± 0.553
0.582AspHis: 0.582 ± 0.308
1.747AspIle: 1.747 ± 1.297
4.077AspLys: 4.077 ± 0.064
4.659AspLeu: 4.659 ± 3.088
0.582AspMet: 0.582 ± 0.308
0.582AspAsn: 0.582 ± 0.308
2.912AspPro: 2.912 ± 0.431
2.33AspGln: 2.33 ± 1.233
5.824AspArg: 5.824 ± 1.972
4.077AspSer: 4.077 ± 0.064
4.659AspThr: 4.659 ± 0.245
3.494AspVal: 3.494 ± 0.372
0.0AspTrp: 0.0 ± 0.0
0.582AspTyr: 0.582 ± 0.308
0.0AspXaa: 0.0 ± 0.0
Glu
5.242GluAla: 5.242 ± 1.669
0.582GluCys: 0.582 ± 0.308
4.077GluAsp: 4.077 ± 0.064
7.571GluGlu: 7.571 ± 4.008
4.077GluPhe: 4.077 ± 1.175
1.747GluGly: 1.747 ± 0.925
0.582GluHis: 0.582 ± 0.308
5.242GluIle: 5.242 ± 0.553
1.747GluLys: 1.747 ± 0.925
5.242GluLeu: 5.242 ± 1.664
2.33GluMet: 2.33 ± 1.233
4.077GluAsn: 4.077 ± 0.064
2.912GluPro: 2.912 ± 1.542
3.494GluGln: 3.494 ± 1.85
4.077GluArg: 4.077 ± 0.064
2.912GluSer: 2.912 ± 0.431
4.659GluThr: 4.659 ± 0.245
4.659GluVal: 4.659 ± 1.356
0.582GluTrp: 0.582 ± 0.308
1.747GluTyr: 1.747 ± 0.186
0.0GluXaa: 0.0 ± 0.0
Phe
2.33PheAla: 2.33 ± 0.122
1.165PheCys: 1.165 ± 0.617
3.494PheAsp: 3.494 ± 0.739
1.747PheGlu: 1.747 ± 0.186
1.165PhePhe: 1.165 ± 0.617
2.33PheGly: 2.33 ± 1.233
0.0PheHis: 0.0 ± 0.0
0.582PheIle: 0.582 ± 0.308
1.165PheLys: 1.165 ± 0.617
5.242PheLeu: 5.242 ± 1.669
1.747PheMet: 1.747 ± 0.565
0.582PheAsn: 0.582 ± 0.308
2.912PhePro: 2.912 ± 0.68
2.33PheGln: 2.33 ± 1.233
1.747PheArg: 1.747 ± 0.186
3.494PheSer: 3.494 ± 0.372
1.747PheThr: 1.747 ± 0.925
2.33PheVal: 2.33 ± 0.122
1.165PheTrp: 1.165 ± 0.617
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.747GlyAla: 1.747 ± 0.186
1.165GlyCys: 1.165 ± 0.617
2.912GlyAsp: 2.912 ± 1.542
6.407GlyGlu: 6.407 ± 1.17
4.659GlyPhe: 4.659 ± 1.356
3.494GlyGly: 3.494 ± 0.739
0.0GlyHis: 0.0 ± 0.0
2.33GlyIle: 2.33 ± 0.122
1.165GlyLys: 1.165 ± 0.617
7.571GlyLeu: 7.571 ± 1.547
1.165GlyMet: 1.165 ± 0.617
0.582GlyAsn: 0.582 ± 0.803
1.165GlyPro: 1.165 ± 0.617
1.747GlyGln: 1.747 ± 0.186
4.077GlyArg: 4.077 ± 1.175
4.659GlySer: 4.659 ± 0.866
3.494GlyThr: 3.494 ± 1.85
8.736GlyVal: 8.736 ± 5.374
1.165GlyTrp: 1.165 ± 0.494
0.582GlyTyr: 0.582 ± 0.308
0.0GlyXaa: 0.0 ± 0.0
His
0.582HisAla: 0.582 ± 0.803
0.582HisCys: 0.582 ± 0.308
0.582HisAsp: 0.582 ± 0.803
0.582HisGlu: 0.582 ± 0.308
0.582HisPhe: 0.582 ± 0.308
0.582HisGly: 0.582 ± 0.308
0.0HisHis: 0.0 ± 0.0
2.912HisIle: 2.912 ± 0.431
0.0HisLys: 0.0 ± 0.0
0.582HisLeu: 0.582 ± 0.803
0.0HisMet: 0.0 ± 0.0
1.165HisAsn: 1.165 ± 0.617
1.165HisPro: 1.165 ± 0.494
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
0.582HisThr: 0.582 ± 0.803
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.582HisTyr: 0.582 ± 0.308
0.0HisXaa: 0.0 ± 0.0
Ile
0.582IleAla: 0.582 ± 0.308
1.165IleCys: 1.165 ± 0.617
1.165IleAsp: 1.165 ± 0.617
2.33IleGlu: 2.33 ± 0.122
2.33IlePhe: 2.33 ± 1.233
2.33IleGly: 2.33 ± 0.989
1.747IleHis: 1.747 ± 0.925
1.747IleIle: 1.747 ± 0.925
2.912IleLys: 2.912 ± 0.431
5.242IleLeu: 5.242 ± 0.558
2.33IleMet: 2.33 ± 1.233
1.165IleAsn: 1.165 ± 0.494
4.077IlePro: 4.077 ± 0.064
2.912IleGln: 2.912 ± 0.431
2.912IleArg: 2.912 ± 0.431
4.077IleSer: 4.077 ± 1.175
2.912IleThr: 2.912 ± 0.431
5.824IleVal: 5.824 ± 1.361
0.0IleTrp: 0.0 ± 0.0
1.165IleTyr: 1.165 ± 0.494
0.0IleXaa: 0.0 ± 0.0
Lys
2.912LysAla: 2.912 ± 0.431
1.165LysCys: 1.165 ± 0.617
1.165LysAsp: 1.165 ± 0.617
4.077LysGlu: 4.077 ± 2.158
2.33LysPhe: 2.33 ± 0.122
4.077LysGly: 4.077 ± 0.064
0.0LysHis: 0.0 ± 0.0
1.165LysIle: 1.165 ± 0.617
6.407LysLys: 6.407 ± 1.17
6.989LysLeu: 6.989 ± 0.367
0.582LysMet: 0.582 ± 0.308
3.494LysAsn: 3.494 ± 1.483
3.494LysPro: 3.494 ± 0.739
1.165LysGln: 1.165 ± 0.494
2.33LysArg: 2.33 ± 1.233
4.077LysSer: 4.077 ± 1.047
1.165LysThr: 1.165 ± 0.494
5.242LysVal: 5.242 ± 0.553
1.747LysTrp: 1.747 ± 1.297
0.582LysTyr: 0.582 ± 0.308
0.0LysXaa: 0.0 ± 0.0
Leu
3.494LeuAla: 3.494 ± 0.372
1.747LeuCys: 1.747 ± 0.925
6.989LeuAsp: 6.989 ± 1.478
6.407LeuGlu: 6.407 ± 1.17
3.494LeuPhe: 3.494 ± 0.372
4.077LeuGly: 4.077 ± 0.064
1.165LeuHis: 1.165 ± 0.494
1.165LeuIle: 1.165 ± 1.605
4.659LeuLys: 4.659 ± 0.245
5.242LeuLeu: 5.242 ± 0.553
3.494LeuMet: 3.494 ± 1.85
4.077LeuAsn: 4.077 ± 1.047
6.407LeuPro: 6.407 ± 0.059
3.494LeuGln: 3.494 ± 1.483
6.407LeuArg: 6.407 ± 1.17
4.077LeuSer: 4.077 ± 2.286
4.659LeuThr: 4.659 ± 1.977
8.736LeuVal: 8.736 ± 2.403
1.747LeuTrp: 1.747 ± 1.297
2.912LeuTyr: 2.912 ± 0.68
0.0LeuXaa: 0.0 ± 0.0
Met
2.33MetAla: 2.33 ± 0.122
0.0MetCys: 0.0 ± 0.0
2.33MetAsp: 2.33 ± 1.233
2.912MetGlu: 2.912 ± 0.68
0.582MetPhe: 0.582 ± 0.803
2.33MetGly: 2.33 ± 0.989
1.165MetHis: 1.165 ± 1.605
2.33MetIle: 2.33 ± 1.233
0.582MetLys: 0.582 ± 0.803
2.33MetLeu: 2.33 ± 1.233
0.582MetMet: 0.582 ± 0.803
1.747MetAsn: 1.747 ± 0.186
2.33MetPro: 2.33 ± 0.122
1.165MetGln: 1.165 ± 0.494
3.494MetArg: 3.494 ± 1.85
0.0MetSer: 0.0 ± 0.0
2.33MetThr: 2.33 ± 0.122
2.33MetVal: 2.33 ± 0.122
0.0MetTrp: 0.0 ± 0.0
1.747MetTyr: 1.747 ± 0.925
0.0MetXaa: 0.0 ± 0.0
Asn
2.33AsnAla: 2.33 ± 0.122
1.165AsnCys: 1.165 ± 0.494
0.582AsnAsp: 0.582 ± 0.803
2.912AsnGlu: 2.912 ± 0.68
2.33AsnPhe: 2.33 ± 0.122
3.494AsnGly: 3.494 ± 0.372
0.0AsnHis: 0.0 ± 0.0
2.33AsnIle: 2.33 ± 0.989
3.494AsnLys: 3.494 ± 0.739
3.494AsnLeu: 3.494 ± 1.483
2.33AsnMet: 2.33 ± 0.989
1.165AsnAsn: 1.165 ± 1.605
4.659AsnPro: 4.659 ± 1.356
1.747AsnGln: 1.747 ± 0.186
6.407AsnArg: 6.407 ± 1.17
2.912AsnSer: 2.912 ± 1.791
1.747AsnThr: 1.747 ± 0.925
1.747AsnVal: 1.747 ± 0.925
0.582AsnTrp: 0.582 ± 0.308
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.659ProAla: 4.659 ± 1.977
0.0ProCys: 0.0 ± 0.0
5.824ProAsp: 5.824 ± 2.472
4.077ProGlu: 4.077 ± 2.158
2.33ProPhe: 2.33 ± 3.211
4.077ProGly: 4.077 ± 1.047
0.582ProHis: 0.582 ± 0.803
2.33ProIle: 2.33 ± 0.122
0.0ProLys: 0.0 ± 0.0
8.154ProLeu: 8.154 ± 0.127
1.165ProMet: 1.165 ± 0.494
1.747ProAsn: 1.747 ± 0.186
5.824ProPro: 5.824 ± 0.861
1.747ProGln: 1.747 ± 0.186
2.912ProArg: 2.912 ± 0.431
5.242ProSer: 5.242 ± 0.558
3.494ProThr: 3.494 ± 0.739
4.077ProVal: 4.077 ± 1.047
0.582ProTrp: 0.582 ± 0.308
2.33ProTyr: 2.33 ± 0.122
0.0ProXaa: 0.0 ± 0.0
Gln
1.747GlnAla: 1.747 ± 1.297
0.582GlnCys: 0.582 ± 0.308
2.912GlnAsp: 2.912 ± 1.542
2.33GlnGlu: 2.33 ± 0.122
1.747GlnPhe: 1.747 ± 0.925
1.747GlnGly: 1.747 ± 1.297
0.0GlnHis: 0.0 ± 0.0
2.33GlnIle: 2.33 ± 1.233
2.912GlnLys: 2.912 ± 1.542
2.912GlnLeu: 2.912 ± 1.542
4.077GlnMet: 4.077 ± 1.175
0.582GlnAsn: 0.582 ± 0.308
1.165GlnPro: 1.165 ± 0.494
3.494GlnGln: 3.494 ± 0.372
5.242GlnArg: 5.242 ± 1.664
1.165GlnSer: 1.165 ± 0.617
5.242GlnThr: 5.242 ± 2.775
4.659GlnVal: 4.659 ± 1.977
2.33GlnTrp: 2.33 ± 0.989
0.582GlnTyr: 0.582 ± 0.803
0.0GlnXaa: 0.0 ± 0.0
Arg
4.659ArgAla: 4.659 ± 0.245
0.0ArgCys: 0.0 ± 0.0
4.659ArgAsp: 4.659 ± 0.245
6.989ArgGlu: 6.989 ± 1.478
2.912ArgPhe: 2.912 ± 1.542
4.077ArgGly: 4.077 ± 1.047
1.165ArgHis: 1.165 ± 0.494
2.33ArgIle: 2.33 ± 1.233
6.407ArgLys: 6.407 ± 0.059
4.077ArgLeu: 4.077 ± 2.158
2.912ArgMet: 2.912 ± 0.431
4.077ArgAsn: 4.077 ± 0.064
1.747ArgPro: 1.747 ± 0.925
4.659ArgGln: 4.659 ± 0.866
6.989ArgArg: 6.989 ± 1.855
4.077ArgSer: 4.077 ± 1.047
4.659ArgThr: 4.659 ± 0.866
4.659ArgVal: 4.659 ± 0.245
0.0ArgTrp: 0.0 ± 0.0
1.747ArgTyr: 1.747 ± 0.925
0.0ArgXaa: 0.0 ± 0.0
Ser
3.494SerAla: 3.494 ± 0.739
0.0SerCys: 0.0 ± 0.0
4.659SerAsp: 4.659 ± 0.245
2.912SerGlu: 2.912 ± 0.68
0.0SerPhe: 0.0 ± 0.0
4.077SerGly: 4.077 ± 4.508
1.747SerHis: 1.747 ± 0.186
4.077SerIle: 4.077 ± 2.286
3.494SerLys: 3.494 ± 0.372
2.912SerLeu: 2.912 ± 0.431
4.077SerMet: 4.077 ± 0.913
4.659SerAsn: 4.659 ± 1.977
4.077SerPro: 4.077 ± 3.397
5.242SerGln: 5.242 ± 1.664
3.494SerArg: 3.494 ± 0.372
11.066SerSer: 11.066 ± 3.03
5.242SerThr: 5.242 ± 2.78
5.824SerVal: 5.824 ± 0.25
1.165SerTrp: 1.165 ± 0.617
1.165SerTyr: 1.165 ± 1.605
0.0SerXaa: 0.0 ± 0.0
Thr
2.912ThrAla: 2.912 ± 1.791
1.165ThrCys: 1.165 ± 1.605
2.912ThrAsp: 2.912 ± 1.791
2.912ThrGlu: 2.912 ± 1.542
1.747ThrPhe: 1.747 ± 0.186
2.912ThrGly: 2.912 ± 0.68
1.165ThrHis: 1.165 ± 0.617
6.407ThrIle: 6.407 ± 1.17
1.747ThrLys: 1.747 ± 0.925
4.659ThrLeu: 4.659 ± 0.245
0.582ThrMet: 0.582 ± 0.803
4.077ThrAsn: 4.077 ± 2.158
6.989ThrPro: 6.989 ± 4.077
4.077ThrGln: 4.077 ± 2.158
3.494ThrArg: 3.494 ± 1.85
5.242ThrSer: 5.242 ± 2.78
4.077ThrThr: 4.077 ± 3.397
3.494ThrVal: 3.494 ± 0.739
0.582ThrTrp: 0.582 ± 0.308
0.582ThrTyr: 0.582 ± 0.308
0.0ThrXaa: 0.0 ± 0.0
Val
4.659ValAla: 4.659 ± 0.245
0.582ValCys: 0.582 ± 0.308
4.077ValAsp: 4.077 ± 1.047
5.824ValGlu: 5.824 ± 0.861
2.912ValPhe: 2.912 ± 1.542
4.077ValGly: 4.077 ± 0.064
0.0ValHis: 0.0 ± 0.0
4.077ValIle: 4.077 ± 0.064
6.407ValLys: 6.407 ± 0.059
6.989ValLeu: 6.989 ± 0.744
1.747ValMet: 1.747 ± 2.408
4.077ValAsn: 4.077 ± 1.047
4.659ValPro: 4.659 ± 0.245
2.912ValGln: 2.912 ± 0.68
5.242ValArg: 5.242 ± 0.558
8.154ValSer: 8.154 ± 2.349
4.659ValThr: 4.659 ± 1.977
9.319ValVal: 9.319 ± 0.489
0.582ValTrp: 0.582 ± 0.308
2.33ValTyr: 2.33 ± 1.233
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.582TrpAsp: 0.582 ± 0.803
0.582TrpGlu: 0.582 ± 0.308
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.582TrpIle: 0.582 ± 0.308
1.165TrpLys: 1.165 ± 0.617
0.0TrpLeu: 0.0 ± 0.0
1.165TrpMet: 1.165 ± 0.617
1.747TrpAsn: 1.747 ± 0.186
0.582TrpPro: 0.582 ± 0.308
0.582TrpGln: 0.582 ± 0.308
2.33TrpArg: 2.33 ± 0.122
2.33TrpSer: 2.33 ± 2.1
1.747TrpThr: 1.747 ± 0.186
0.582TrpVal: 0.582 ± 0.308
0.0TrpTrp: 0.0 ± 0.0
0.582TrpTyr: 0.582 ± 0.803
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.33TyrAla: 2.33 ± 0.989
0.0TyrCys: 0.0 ± 0.0
0.582TyrAsp: 0.582 ± 0.308
0.582TyrGlu: 0.582 ± 0.308
0.0TyrPhe: 0.0 ± 0.0
2.912TyrGly: 2.912 ± 1.542
0.0TyrHis: 0.0 ± 0.0
1.747TyrIle: 1.747 ± 0.925
0.582TyrLys: 0.582 ± 0.308
2.33TyrLeu: 2.33 ± 1.233
0.582TyrMet: 0.582 ± 0.803
2.33TyrAsn: 2.33 ± 0.989
3.494TyrPro: 3.494 ± 1.483
1.165TyrGln: 1.165 ± 0.494
0.582TyrArg: 0.582 ± 0.308
1.165TyrSer: 1.165 ± 1.605
1.165TyrThr: 1.165 ± 0.494
0.582TyrVal: 0.582 ± 0.308
1.747TyrTrp: 1.747 ± 0.186
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1718 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski