Amino acid dipepetide frequency for Mount Mabu Lophuromys virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.555AlaAla: 3.555 ± 0.698
0.748AlaCys: 0.748 ± 0.365
1.871AlaAsp: 1.871 ± 0.975
2.993AlaGlu: 2.993 ± 0.641
1.123AlaPhe: 1.123 ± 0.382
3.368AlaGly: 3.368 ± 1.2
0.935AlaHis: 0.935 ± 0.273
5.613AlaIle: 5.613 ± 1.213
2.806AlaLys: 2.806 ± 0.379
5.613AlaLeu: 5.613 ± 1.369
0.748AlaMet: 0.748 ± 0.351
3.929AlaAsn: 3.929 ± 0.989
1.31AlaPro: 1.31 ± 0.691
1.871AlaGln: 1.871 ± 0.429
2.058AlaArg: 2.058 ± 0.445
2.432AlaSer: 2.432 ± 0.598
3.181AlaThr: 3.181 ± 1.199
2.806AlaVal: 2.806 ± 1.075
0.935AlaTrp: 0.935 ± 0.406
0.748AlaTyr: 0.748 ± 0.353
0.0AlaXaa: 0.0 ± 0.0
Cys
1.123CysAla: 1.123 ± 0.571
0.374CysCys: 0.374 ± 0.252
0.748CysAsp: 0.748 ± 0.504
0.561CysGlu: 0.561 ± 0.378
0.748CysPhe: 0.748 ± 0.353
0.748CysGly: 0.748 ± 0.232
0.748CysHis: 0.748 ± 0.497
0.748CysIle: 0.748 ± 0.315
0.187CysLys: 0.187 ± 0.186
1.123CysLeu: 1.123 ± 0.439
0.187CysMet: 0.187 ± 0.126
0.187CysAsn: 0.187 ± 0.177
0.748CysPro: 0.748 ± 0.497
0.748CysGln: 0.748 ± 0.247
0.748CysArg: 0.748 ± 0.24
2.245CysSer: 2.245 ± 0.767
0.935CysThr: 0.935 ± 0.355
0.935CysVal: 0.935 ± 0.492
0.187CysTrp: 0.187 ± 0.126
1.497CysTyr: 1.497 ± 0.443
0.0CysXaa: 0.0 ± 0.0
Asp
1.871AspAla: 1.871 ± 0.892
0.748AspCys: 0.748 ± 0.372
3.929AspAsp: 3.929 ± 1.003
3.555AspGlu: 3.555 ± 0.813
2.806AspPhe: 2.806 ± 0.553
1.871AspGly: 1.871 ± 0.953
2.058AspHis: 2.058 ± 0.637
3.742AspIle: 3.742 ± 0.544
3.555AspLys: 3.555 ± 0.861
5.8AspLeu: 5.8 ± 0.587
1.871AspMet: 1.871 ± 0.526
2.245AspAsn: 2.245 ± 0.711
3.555AspPro: 3.555 ± 0.764
2.619AspGln: 2.619 ± 0.496
4.303AspArg: 4.303 ± 0.522
2.806AspSer: 2.806 ± 0.664
3.742AspThr: 3.742 ± 0.841
3.742AspVal: 3.742 ± 0.537
0.187AspTrp: 0.187 ± 0.126
2.245AspTyr: 2.245 ± 0.332
0.0AspXaa: 0.0 ± 0.0
Glu
3.181GluAla: 3.181 ± 0.421
1.497GluCys: 1.497 ± 0.504
5.613GluAsp: 5.613 ± 1.818
3.368GluGlu: 3.368 ± 1.608
2.619GluPhe: 2.619 ± 0.889
2.993GluGly: 2.993 ± 1.169
0.935GluHis: 0.935 ± 0.284
4.677GluIle: 4.677 ± 1.138
2.806GluLys: 2.806 ± 0.505
5.239GluLeu: 5.239 ± 0.765
1.684GluMet: 1.684 ± 0.782
2.619GluAsn: 2.619 ± 0.764
0.935GluPro: 0.935 ± 0.273
2.058GluGln: 2.058 ± 0.459
2.245GluArg: 2.245 ± 0.393
4.303GluSer: 4.303 ± 0.851
4.116GluThr: 4.116 ± 0.54
2.432GluVal: 2.432 ± 0.676
0.935GluTrp: 0.935 ± 0.347
1.31GluTyr: 1.31 ± 0.289
0.0GluXaa: 0.0 ± 0.0
Phe
1.497PheAla: 1.497 ± 0.479
0.935PheCys: 0.935 ± 0.468
0.748PheAsp: 0.748 ± 0.32
1.497PheGlu: 1.497 ± 0.331
1.684PhePhe: 1.684 ± 0.515
1.684PheGly: 1.684 ± 0.61
0.187PheHis: 0.187 ± 0.126
2.245PheIle: 2.245 ± 0.66
1.684PheLys: 1.684 ± 0.393
4.303PheLeu: 4.303 ± 1.219
0.935PheMet: 0.935 ± 0.626
2.619PheAsn: 2.619 ± 0.84
1.497PhePro: 1.497 ± 0.36
0.935PheGln: 0.935 ± 0.428
2.058PheArg: 2.058 ± 0.694
2.245PheSer: 2.245 ± 0.526
2.058PheThr: 2.058 ± 0.665
2.432PheVal: 2.432 ± 0.605
0.748PheTrp: 0.748 ± 0.372
0.374PheTyr: 0.374 ± 0.304
0.0PheXaa: 0.0 ± 0.0
Gly
2.619GlyAla: 2.619 ± 0.715
1.871GlyCys: 1.871 ± 0.944
4.116GlyAsp: 4.116 ± 0.88
2.993GlyGlu: 2.993 ± 0.774
1.684GlyPhe: 1.684 ± 0.532
3.181GlyGly: 3.181 ± 0.937
1.31GlyHis: 1.31 ± 0.531
4.864GlyIle: 4.864 ± 1.146
2.806GlyLys: 2.806 ± 1.096
3.929GlyLeu: 3.929 ± 0.597
1.31GlyMet: 1.31 ± 0.333
3.742GlyAsn: 3.742 ± 0.956
2.432GlyPro: 2.432 ± 0.945
1.31GlyGln: 1.31 ± 0.52
3.181GlyArg: 3.181 ± 0.897
4.677GlySer: 4.677 ± 1.016
3.929GlyThr: 3.929 ± 2.034
4.303GlyVal: 4.303 ± 1.136
0.374GlyTrp: 0.374 ± 0.175
2.806GlyTyr: 2.806 ± 0.589
0.0GlyXaa: 0.0 ± 0.0
His
1.123HisAla: 1.123 ± 0.407
0.187HisCys: 0.187 ± 0.126
0.561HisAsp: 0.561 ± 0.408
1.871HisGlu: 1.871 ± 0.638
0.748HisPhe: 0.748 ± 0.205
1.31HisGly: 1.31 ± 0.415
0.374HisHis: 0.374 ± 0.252
0.935HisIle: 0.935 ± 0.263
1.123HisLys: 1.123 ± 0.39
2.619HisLeu: 2.619 ± 1.218
0.561HisMet: 0.561 ± 0.378
1.31HisAsn: 1.31 ± 0.553
0.935HisPro: 0.935 ± 0.418
1.123HisGln: 1.123 ± 0.422
0.748HisArg: 0.748 ± 0.317
1.497HisSer: 1.497 ± 0.504
2.058HisThr: 2.058 ± 0.81
1.497HisVal: 1.497 ± 0.427
0.0HisTrp: 0.0 ± 0.0
0.748HisTyr: 0.748 ± 0.386
0.0HisXaa: 0.0 ± 0.0
Ile
4.303IleAla: 4.303 ± 0.638
0.935IleCys: 0.935 ± 0.357
4.864IleAsp: 4.864 ± 0.736
5.239IleGlu: 5.239 ± 0.262
1.871IlePhe: 1.871 ± 0.244
2.806IleGly: 2.806 ± 0.757
1.871IleHis: 1.871 ± 0.795
6.548IleIle: 6.548 ± 1.142
5.987IleLys: 5.987 ± 0.994
5.426IleLeu: 5.426 ± 0.828
2.432IleMet: 2.432 ± 0.425
5.987IleAsn: 5.987 ± 1.214
4.864IlePro: 4.864 ± 1.091
4.116IleGln: 4.116 ± 0.912
2.993IleArg: 2.993 ± 0.619
4.864IleSer: 4.864 ± 1.172
4.116IleThr: 4.116 ± 0.637
4.677IleVal: 4.677 ± 0.799
0.748IleTrp: 0.748 ± 0.438
3.742IleTyr: 3.742 ± 1.375
0.0IleXaa: 0.0 ± 0.0
Lys
3.742LysAla: 3.742 ± 0.472
0.561LysCys: 0.561 ± 0.378
4.303LysAsp: 4.303 ± 1.092
4.677LysGlu: 4.677 ± 0.781
1.123LysPhe: 1.123 ± 0.364
3.181LysGly: 3.181 ± 0.79
0.748LysHis: 0.748 ± 0.442
2.993LysIle: 2.993 ± 0.799
4.303LysLys: 4.303 ± 1.425
6.174LysLeu: 6.174 ± 1.409
2.245LysMet: 2.245 ± 0.755
2.619LysAsn: 2.619 ± 0.811
2.058LysPro: 2.058 ± 0.72
0.561LysGln: 0.561 ± 0.255
3.181LysArg: 3.181 ± 0.785
5.8LysSer: 5.8 ± 1.337
4.116LysThr: 4.116 ± 1.536
4.116LysVal: 4.116 ± 0.619
0.187LysTrp: 0.187 ± 0.177
3.555LysTyr: 3.555 ± 0.577
0.0LysXaa: 0.0 ± 0.0
Leu
5.426LeuAla: 5.426 ± 0.834
1.497LeuCys: 1.497 ± 0.833
6.361LeuAsp: 6.361 ± 0.936
5.051LeuGlu: 5.051 ± 0.972
2.806LeuPhe: 2.806 ± 0.988
6.174LeuGly: 6.174 ± 0.92
2.432LeuHis: 2.432 ± 0.512
9.355LeuIle: 9.355 ± 1.533
5.239LeuLys: 5.239 ± 1.137
5.987LeuLeu: 5.987 ± 1.326
2.058LeuMet: 2.058 ± 0.348
7.484LeuAsn: 7.484 ± 1.142
1.497LeuPro: 1.497 ± 0.548
3.181LeuGln: 3.181 ± 0.815
4.116LeuArg: 4.116 ± 0.838
11.413LeuSer: 11.413 ± 0.82
7.484LeuThr: 7.484 ± 0.964
3.181LeuVal: 3.181 ± 0.663
0.561LeuTrp: 0.561 ± 0.223
2.619LeuTyr: 2.619 ± 1.011
0.0LeuXaa: 0.0 ± 0.0
Met
0.935MetAla: 0.935 ± 0.381
0.374MetCys: 0.374 ± 0.252
1.497MetAsp: 1.497 ± 0.504
1.31MetGlu: 1.31 ± 0.546
0.561MetPhe: 0.561 ± 0.268
0.935MetGly: 0.935 ± 0.456
0.0MetHis: 0.0 ± 0.0
3.555MetIle: 3.555 ± 0.377
2.058MetLys: 2.058 ± 0.46
2.432MetLeu: 2.432 ± 0.679
1.31MetMet: 1.31 ± 0.391
1.497MetAsn: 1.497 ± 0.489
0.748MetPro: 0.748 ± 0.241
0.748MetGln: 0.748 ± 0.394
1.31MetArg: 1.31 ± 0.353
2.058MetSer: 2.058 ± 0.796
2.432MetThr: 2.432 ± 0.458
2.245MetVal: 2.245 ± 0.915
0.374MetTrp: 0.374 ± 0.212
1.31MetTyr: 1.31 ± 0.318
0.0MetXaa: 0.0 ± 0.0
Asn
2.619AsnAla: 2.619 ± 0.915
0.935AsnCys: 0.935 ± 0.45
2.432AsnAsp: 2.432 ± 0.8
2.245AsnGlu: 2.245 ± 0.335
1.123AsnPhe: 1.123 ± 0.492
3.555AsnGly: 3.555 ± 1.098
2.245AsnHis: 2.245 ± 0.576
4.303AsnIle: 4.303 ± 0.737
3.929AsnLys: 3.929 ± 0.922
7.671AsnLeu: 7.671 ± 1.807
1.497AsnMet: 1.497 ± 0.339
4.677AsnAsn: 4.677 ± 0.67
4.49AsnPro: 4.49 ± 0.441
2.058AsnGln: 2.058 ± 0.437
3.368AsnArg: 3.368 ± 0.701
4.303AsnSer: 4.303 ± 0.918
3.929AsnThr: 3.929 ± 0.781
2.619AsnVal: 2.619 ± 0.739
1.123AsnTrp: 1.123 ± 0.421
2.806AsnTyr: 2.806 ± 0.55
0.0AsnXaa: 0.0 ± 0.0
Pro
1.123ProAla: 1.123 ± 0.514
0.0ProCys: 0.0 ± 0.0
1.497ProAsp: 1.497 ± 0.351
1.684ProGlu: 1.684 ± 0.516
1.123ProPhe: 1.123 ± 0.526
3.368ProGly: 3.368 ± 1.347
0.374ProHis: 0.374 ± 0.252
2.806ProIle: 2.806 ± 0.467
4.116ProLys: 4.116 ± 0.475
2.058ProLeu: 2.058 ± 0.543
0.935ProMet: 0.935 ± 0.385
2.806ProAsn: 2.806 ± 0.674
1.497ProPro: 1.497 ± 0.329
0.748ProGln: 0.748 ± 0.666
3.368ProArg: 3.368 ± 0.781
4.116ProSer: 4.116 ± 0.573
1.871ProThr: 1.871 ± 0.415
3.368ProVal: 3.368 ± 0.804
0.374ProTrp: 0.374 ± 0.212
2.619ProTyr: 2.619 ± 0.632
0.0ProXaa: 0.0 ± 0.0
Gln
1.684GlnAla: 1.684 ± 0.536
0.187GlnCys: 0.187 ± 0.177
1.684GlnAsp: 1.684 ± 0.514
2.619GlnGlu: 2.619 ± 0.529
0.374GlnPhe: 0.374 ± 0.252
1.497GlnGly: 1.497 ± 0.386
1.123GlnHis: 1.123 ± 0.486
3.555GlnIle: 3.555 ± 0.46
3.181GlnLys: 3.181 ± 0.572
4.49GlnLeu: 4.49 ± 0.956
1.123GlnMet: 1.123 ± 0.439
1.31GlnAsn: 1.31 ± 0.661
0.374GlnPro: 0.374 ± 0.389
1.497GlnGln: 1.497 ± 0.531
1.31GlnArg: 1.31 ± 0.619
3.181GlnSer: 3.181 ± 0.785
2.245GlnThr: 2.245 ± 0.244
2.619GlnVal: 2.619 ± 0.801
0.187GlnTrp: 0.187 ± 0.177
0.748GlnTyr: 0.748 ± 0.247
0.0GlnXaa: 0.0 ± 0.0
Arg
2.619ArgAla: 2.619 ± 0.683
0.561ArgCys: 0.561 ± 0.208
3.742ArgAsp: 3.742 ± 0.647
1.497ArgGlu: 1.497 ± 0.412
1.31ArgPhe: 1.31 ± 0.467
2.993ArgGly: 2.993 ± 0.642
0.935ArgHis: 0.935 ± 0.382
4.677ArgIle: 4.677 ± 0.58
2.806ArgLys: 2.806 ± 0.575
4.864ArgLeu: 4.864 ± 1.187
0.935ArgMet: 0.935 ± 0.387
2.432ArgAsn: 2.432 ± 0.589
2.245ArgPro: 2.245 ± 0.566
1.497ArgGln: 1.497 ± 0.427
2.993ArgArg: 2.993 ± 0.938
5.051ArgSer: 5.051 ± 1.559
2.806ArgThr: 2.806 ± 0.872
3.929ArgVal: 3.929 ± 0.863
1.123ArgTrp: 1.123 ± 0.386
1.497ArgTyr: 1.497 ± 0.237
0.0ArgXaa: 0.0 ± 0.0
Ser
2.432SerAla: 2.432 ± 0.769
0.561SerCys: 0.561 ± 0.208
3.929SerAsp: 3.929 ± 0.608
4.116SerGlu: 4.116 ± 0.844
3.555SerPhe: 3.555 ± 0.835
6.548SerGly: 6.548 ± 2.12
1.497SerHis: 1.497 ± 0.415
6.361SerIle: 6.361 ± 0.748
3.742SerLys: 3.742 ± 0.977
9.542SerLeu: 9.542 ± 1.517
2.619SerMet: 2.619 ± 0.377
5.613SerAsn: 5.613 ± 1.102
2.619SerPro: 2.619 ± 0.708
3.368SerGln: 3.368 ± 0.807
4.49SerArg: 4.49 ± 0.781
7.109SerSer: 7.109 ± 0.91
6.735SerThr: 6.735 ± 1.275
5.051SerVal: 5.051 ± 0.989
0.561SerTrp: 0.561 ± 0.248
4.116SerTyr: 4.116 ± 0.89
0.0SerXaa: 0.0 ± 0.0
Thr
3.929ThrAla: 3.929 ± 0.946
1.123ThrCys: 1.123 ± 0.352
3.742ThrAsp: 3.742 ± 0.683
3.929ThrGlu: 3.929 ± 0.973
1.684ThrPhe: 1.684 ± 0.551
4.303ThrGly: 4.303 ± 1.223
1.123ThrHis: 1.123 ± 0.588
4.677ThrIle: 4.677 ± 0.83
3.555ThrLys: 3.555 ± 1.259
5.426ThrLeu: 5.426 ± 1.195
1.871ThrMet: 1.871 ± 0.67
3.742ThrAsn: 3.742 ± 0.577
2.619ThrPro: 2.619 ± 0.918
3.555ThrGln: 3.555 ± 1.031
3.742ThrArg: 3.742 ± 0.923
6.735ThrSer: 6.735 ± 1.359
4.49ThrThr: 4.49 ± 1.25
4.116ThrVal: 4.116 ± 0.912
1.31ThrTrp: 1.31 ± 0.31
3.555ThrTyr: 3.555 ± 0.727
0.0ThrXaa: 0.0 ± 0.0
Val
3.181ValAla: 3.181 ± 0.765
1.123ValCys: 1.123 ± 0.312
2.993ValAsp: 2.993 ± 0.638
3.555ValGlu: 3.555 ± 0.696
2.245ValPhe: 2.245 ± 0.7
4.116ValGly: 4.116 ± 0.546
0.748ValHis: 0.748 ± 0.315
3.181ValIle: 3.181 ± 0.559
2.806ValLys: 2.806 ± 0.909
5.051ValLeu: 5.051 ± 1.076
1.123ValMet: 1.123 ± 0.537
4.864ValAsn: 4.864 ± 0.432
2.245ValPro: 2.245 ± 0.549
1.497ValGln: 1.497 ± 0.601
3.181ValArg: 3.181 ± 0.544
5.426ValSer: 5.426 ± 1.299
5.239ValThr: 5.239 ± 1.484
2.993ValVal: 2.993 ± 0.792
0.187ValTrp: 0.187 ± 0.126
2.806ValTyr: 2.806 ± 0.583
0.0ValXaa: 0.0 ± 0.0
Trp
0.561TrpAla: 0.561 ± 0.224
0.187TrpCys: 0.187 ± 0.177
0.374TrpAsp: 0.374 ± 0.252
1.123TrpGlu: 1.123 ± 0.404
0.748TrpPhe: 0.748 ± 0.247
0.374TrpGly: 0.374 ± 0.239
0.561TrpHis: 0.561 ± 0.248
0.561TrpIle: 0.561 ± 0.209
0.748TrpLys: 0.748 ± 0.232
1.31TrpLeu: 1.31 ± 0.254
0.187TrpMet: 0.187 ± 0.186
0.187TrpAsn: 0.187 ± 0.126
0.187TrpPro: 0.187 ± 0.126
0.0TrpGln: 0.0 ± 0.0
0.561TrpArg: 0.561 ± 0.242
0.935TrpSer: 0.935 ± 0.381
0.374TrpThr: 0.374 ± 0.181
0.561TrpVal: 0.561 ± 0.209
0.374TrpTrp: 0.374 ± 0.175
0.748TrpTyr: 0.748 ± 0.215
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.123TyrAla: 1.123 ± 0.301
1.123TyrCys: 1.123 ± 0.531
2.245TyrAsp: 2.245 ± 0.495
1.684TyrGlu: 1.684 ± 0.237
2.432TyrPhe: 2.432 ± 0.532
2.432TyrGly: 2.432 ± 0.369
1.123TyrHis: 1.123 ± 0.54
2.993TyrIle: 2.993 ± 0.991
2.806TyrLys: 2.806 ± 0.813
4.864TyrLeu: 4.864 ± 1.035
1.871TyrMet: 1.871 ± 0.342
2.058TyrAsn: 2.058 ± 0.806
2.993TyrPro: 2.993 ± 1.021
1.497TyrGln: 1.497 ± 0.24
0.561TyrArg: 0.561 ± 0.242
3.555TyrSer: 3.555 ± 0.655
3.368TyrThr: 3.368 ± 0.6
0.935TyrVal: 0.935 ± 0.41
0.187TyrTrp: 0.187 ± 0.126
1.497TyrTyr: 1.497 ± 0.672
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (5346 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski