Amino acid dipepetide frequency for Dermacoccus sp. 147Ba

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.409AlaAla: 17.409 ± 0.214	0.997AlaCys: 0.997 ± 0.03	7.946AlaAsp: 7.946 ± 0.094	7.682AlaGlu: 7.682 ± 0.101	3.688AlaPhe: 3.688 ± 0.071	11.33AlaGly: 11.33 ± 0.128	2.751AlaHis: 2.751 ± 0.064	4.255AlaIle: 4.255 ± 0.077	3.693AlaLys: 3.693 ± 0.071	13.452AlaLeu: 13.452 ± 0.159	2.988AlaMet: 2.988 ± 0.06	2.437AlaAsn: 2.437 ± 0.054	6.035AlaPro: 6.035 ± 0.096	3.886AlaGln: 3.886 ± 0.068	9.358AlaArg: 9.358 ± 0.117	7.156AlaSer: 7.156 ± 0.098	7.407AlaThr: 7.407 ± 0.093	10.761AlaVal: 10.761 ± 0.132	2.029AlaTrp: 2.029 ± 0.048	2.444AlaTyr: 2.444 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.903CysAla: 0.903 ± 0.036	0.078CysCys: 0.078 ± 0.01	0.476CysAsp: 0.476 ± 0.023	0.395CysGlu: 0.395 ± 0.021	0.239CysPhe: 0.239 ± 0.015	0.83CysGly: 0.83 ± 0.029	0.169CysHis: 0.169 ± 0.013	0.26CysIle: 0.26 ± 0.016	0.118CysLys: 0.118 ± 0.011	0.646CysLeu: 0.646 ± 0.031	0.116CysMet: 0.116 ± 0.011	0.122CysAsn: 0.122 ± 0.012	0.417CysPro: 0.417 ± 0.024	0.128CysGln: 0.128 ± 0.012	0.468CysArg: 0.468 ± 0.024	0.479CysSer: 0.479 ± 0.022	0.428CysThr: 0.428 ± 0.024	0.619CysVal: 0.619 ± 0.03	0.095CysTrp: 0.095 ± 0.011	0.163CysTyr: 0.163 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	9.058AspAla: 9.058 ± 0.105	0.283AspCys: 0.283 ± 0.017	5.054AspAsp: 5.054 ± 0.096	5.447AspGlu: 5.447 ± 0.103	1.681AspPhe: 1.681 ± 0.042	6.15AspGly: 6.15 ± 0.095	1.356AspHis: 1.356 ± 0.036	2.397AspIle: 2.397 ± 0.05	1.487AspLys: 1.487 ± 0.049	6.194AspLeu: 6.194 ± 0.091	1.064AspMet: 1.064 ± 0.035	1.116AspAsn: 1.116 ± 0.036	3.517AspPro: 3.517 ± 0.068	1.35AspGln: 1.35 ± 0.041	3.68AspArg: 3.68 ± 0.072	2.796AspSer: 2.796 ± 0.061	2.841AspThr: 2.841 ± 0.058	6.324AspVal: 6.324 ± 0.1	0.77AspTrp: 0.77 ± 0.037	1.104AspTyr: 1.104 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	7.953GluAla: 7.953 ± 0.1	0.413GluCys: 0.413 ± 0.025	2.898GluAsp: 2.898 ± 0.065	3.394GluGlu: 3.394 ± 0.072	1.712GluPhe: 1.712 ± 0.039	4.76GluGly: 4.76 ± 0.07	1.749GluHis: 1.749 ± 0.044	2.624GluIle: 2.624 ± 0.05	2.03GluLys: 2.03 ± 0.05	6.074GluLeu: 6.074 ± 0.088	1.215GluMet: 1.215 ± 0.036	1.529GluAsn: 1.529 ± 0.044	3.009GluPro: 3.009 ± 0.064	2.368GluGln: 2.368 ± 0.053	6.252GluArg: 6.252 ± 0.09	3.175GluSer: 3.175 ± 0.069	3.122GluThr: 3.122 ± 0.059	4.824GluVal: 4.824 ± 0.07	0.896GluTrp: 0.896 ± 0.035	1.096GluTyr: 1.096 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.898PheAla: 3.898 ± 0.071	0.255PheCys: 0.255 ± 0.016	2.386PheAsp: 2.386 ± 0.054	1.697PheGlu: 1.697 ± 0.04	0.99PhePhe: 0.99 ± 0.034	3.333PheGly: 3.333 ± 0.059	0.586PheHis: 0.586 ± 0.026	1.009PheIle: 1.009 ± 0.032	0.631PheLys: 0.631 ± 0.025	2.467PheLeu: 2.467 ± 0.06	0.521PheMet: 0.521 ± 0.025	0.643PheAsn: 0.643 ± 0.026	1.267PhePro: 1.267 ± 0.039	0.587PheGln: 0.587 ± 0.023	1.491PheArg: 1.491 ± 0.043	1.653PheSer: 1.653 ± 0.046	2.078PheThr: 2.078 ± 0.046	3.072PheVal: 3.072 ± 0.068	0.417PheTrp: 0.417 ± 0.024	0.617PheTyr: 0.617 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	10.136GlyAla: 10.136 ± 0.12	0.755GlyCys: 0.755 ± 0.033	5.409GlyAsp: 5.409 ± 0.076	5.497GlyGlu: 5.497 ± 0.085	3.143GlyPhe: 3.143 ± 0.056	7.828GlyGly: 7.828 ± 0.128	2.086GlyHis: 2.086 ± 0.045	3.714GlyIle: 3.714 ± 0.062	2.781GlyLys: 2.781 ± 0.056	8.652GlyLeu: 8.652 ± 0.105	2.111GlyMet: 2.111 ± 0.045	1.856GlyAsn: 1.856 ± 0.051	3.715GlyPro: 3.715 ± 0.068	2.635GlyGln: 2.635 ± 0.071	6.621GlyArg: 6.621 ± 0.096	5.356GlySer: 5.356 ± 0.076	5.174GlyThr: 5.174 ± 0.078	7.957GlyVal: 7.957 ± 0.108	1.577GlyTrp: 1.577 ± 0.049	2.177GlyTyr: 2.177 ± 0.052	0.0GlyXaa: 0.0 ± 0.0
His	2.527HisAla: 2.527 ± 0.051	0.193HisCys: 0.193 ± 0.015	1.614HisAsp: 1.614 ± 0.04	1.44HisGlu: 1.44 ± 0.048	0.609HisPhe: 0.609 ± 0.024	2.122HisGly: 2.122 ± 0.055	0.68HisHis: 0.68 ± 0.031	0.707HisIle: 0.707 ± 0.025	0.391HisLys: 0.391 ± 0.023	2.36HisLeu: 2.36 ± 0.062	0.425HisMet: 0.425 ± 0.022	0.407HisAsn: 0.407 ± 0.021	1.533HisPro: 1.533 ± 0.039	0.526HisGln: 0.526 ± 0.023	1.618HisArg: 1.618 ± 0.042	1.034HisSer: 1.034 ± 0.036	1.177HisThr: 1.177 ± 0.041	2.018HisVal: 2.018 ± 0.052	0.335HisTrp: 0.335 ± 0.021	0.437HisTyr: 0.437 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.404IleAla: 5.404 ± 0.088	0.319IleCys: 0.319 ± 0.018	3.019IleAsp: 3.019 ± 0.059	2.599IleGlu: 2.599 ± 0.059	1.016IlePhe: 1.016 ± 0.036	3.88IleGly: 3.88 ± 0.08	0.702IleHis: 0.702 ± 0.024	1.289IleIle: 1.289 ± 0.045	0.962IleLys: 0.962 ± 0.036	2.743IleLeu: 2.743 ± 0.054	0.624IleMet: 0.624 ± 0.025	0.868IleAsn: 0.868 ± 0.033	1.719IlePro: 1.719 ± 0.039	0.76IleGln: 0.76 ± 0.028	2.143IleArg: 2.143 ± 0.046	1.994IleSer: 1.994 ± 0.051	2.506IleThr: 2.506 ± 0.051	3.769IleVal: 3.769 ± 0.062	0.369IleTrp: 0.369 ± 0.018	0.614IleTyr: 0.614 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.616LysAla: 3.616 ± 0.077	0.113LysCys: 0.113 ± 0.012	1.651LysAsp: 1.651 ± 0.048	1.448LysGlu: 1.448 ± 0.041	0.581LysPhe: 0.581 ± 0.025	2.306LysGly: 2.306 ± 0.055	0.584LysHis: 0.584 ± 0.028	1.097LysIle: 1.097 ± 0.04	1.371LysLys: 1.371 ± 0.057	2.33LysLeu: 2.33 ± 0.048	0.559LysMet: 0.559 ± 0.027	0.853LysAsn: 0.853 ± 0.028	1.649LysPro: 1.649 ± 0.05	0.939LysGln: 0.939 ± 0.033	2.021LysArg: 2.021 ± 0.05	1.571LysSer: 1.571 ± 0.052	1.529LysThr: 1.529 ± 0.047	2.39LysVal: 2.39 ± 0.053	0.328LysTrp: 0.328 ± 0.017	0.513LysTyr: 0.513 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	13.903LeuAla: 13.903 ± 0.128	0.648LeuCys: 0.648 ± 0.026	6.733LeuAsp: 6.733 ± 0.093	5.474LeuGlu: 5.474 ± 0.079	2.611LeuPhe: 2.611 ± 0.064	8.806LeuGly: 8.806 ± 0.106	1.87LeuHis: 1.87 ± 0.042	3.123LeuIle: 3.123 ± 0.067	2.218LeuLys: 2.218 ± 0.051	9.125LeuLeu: 9.125 ± 0.142	1.871LeuMet: 1.871 ± 0.048	1.746LeuAsn: 1.746 ± 0.044	5.317LeuPro: 5.317 ± 0.083	2.021LeuGln: 2.021 ± 0.046	7.28LeuArg: 7.28 ± 0.099	5.072LeuSer: 5.072 ± 0.079	6.331LeuThr: 6.331 ± 0.093	9.786LeuVal: 9.786 ± 0.129	1.258LeuTrp: 1.258 ± 0.042	1.483LeuTyr: 1.483 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	2.565MetAla: 2.565 ± 0.059	0.159MetCys: 0.159 ± 0.014	0.932MetAsp: 0.932 ± 0.034	0.822MetGlu: 0.822 ± 0.028	0.654MetPhe: 0.654 ± 0.033	1.623MetGly: 1.623 ± 0.043	0.386MetHis: 0.386 ± 0.02	0.744MetIle: 0.744 ± 0.03	0.701MetLys: 0.701 ± 0.03	2.045MetLeu: 2.045 ± 0.053	0.379MetMet: 0.379 ± 0.02	0.607MetAsn: 0.607 ± 0.024	1.351MetPro: 1.351 ± 0.043	0.527MetGln: 0.527 ± 0.024	1.605MetArg: 1.605 ± 0.042	1.732MetSer: 1.732 ± 0.037	2.005MetThr: 2.005 ± 0.047	1.384MetVal: 1.384 ± 0.036	0.287MetTrp: 0.287 ± 0.015	0.327MetTyr: 0.327 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	2.774AsnAla: 2.774 ± 0.052	0.149AsnCys: 0.149 ± 0.011	1.279AsnAsp: 1.279 ± 0.035	1.212AsnGlu: 1.212 ± 0.038	0.602AsnPhe: 0.602 ± 0.025	1.957AsnGly: 1.957 ± 0.048	0.422AsnHis: 0.422 ± 0.022	0.838AsnIle: 0.838 ± 0.033	0.569AsnLys: 0.569 ± 0.026	2.087AsnLeu: 2.087 ± 0.05	0.413AsnMet: 0.413 ± 0.021	0.515AsnAsn: 0.515 ± 0.026	1.611AsnPro: 1.611 ± 0.045	0.52AsnGln: 0.52 ± 0.025	1.348AsnArg: 1.348 ± 0.042	1.105AsnSer: 1.105 ± 0.039	1.218AsnThr: 1.218 ± 0.04	1.97AsnVal: 1.97 ± 0.053	0.291AsnTrp: 0.291 ± 0.019	0.446AsnTyr: 0.446 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	6.194ProAla: 6.194 ± 0.088	0.257ProCys: 0.257 ± 0.018	3.559ProAsp: 3.559 ± 0.061	3.921ProGlu: 3.921 ± 0.068	1.576ProPhe: 1.576 ± 0.042	4.884ProGly: 4.884 ± 0.076	1.286ProHis: 1.286 ± 0.042	1.731ProIle: 1.731 ± 0.039	1.6ProLys: 1.6 ± 0.047	4.393ProLeu: 4.393 ± 0.069	1.087ProMet: 1.087 ± 0.031	1.264ProAsn: 1.264 ± 0.037	2.174ProPro: 2.174 ± 0.062	1.708ProGln: 1.708 ± 0.047	3.39ProArg: 3.39 ± 0.072	3.405ProSer: 3.405 ± 0.074	3.337ProThr: 3.337 ± 0.074	4.493ProVal: 4.493 ± 0.078	0.84ProTrp: 0.84 ± 0.037	1.069ProTyr: 1.069 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.454GlnAla: 3.454 ± 0.067	0.19GlnCys: 0.19 ± 0.015	1.197GlnAsp: 1.197 ± 0.035	1.306GlnGlu: 1.306 ± 0.039	0.863GlnPhe: 0.863 ± 0.029	2.161GlnGly: 2.161 ± 0.052	0.705GlnHis: 0.705 ± 0.024	1.301GlnIle: 1.301 ± 0.039	0.746GlnLys: 0.746 ± 0.028	2.786GlnLeu: 2.786 ± 0.055	0.62GlnMet: 0.62 ± 0.027	0.678GlnAsn: 0.678 ± 0.034	1.542GlnPro: 1.542 ± 0.042	1.124GlnGln: 1.124 ± 0.046	2.429GlnArg: 2.429 ± 0.058	1.268GlnSer: 1.268 ± 0.042	1.391GlnThr: 1.391 ± 0.039	2.39GlnVal: 2.39 ± 0.047	0.46GlnTrp: 0.46 ± 0.023	0.631GlnTyr: 0.631 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	8.501ArgAla: 8.501 ± 0.12	0.489ArgCys: 0.489 ± 0.023	4.569ArgAsp: 4.569 ± 0.092	5.038ArgGlu: 5.038 ± 0.075	2.221ArgPhe: 2.221 ± 0.047	5.548ArgGly: 5.548 ± 0.099	1.861ArgHis: 1.861 ± 0.045	3.048ArgIle: 3.048 ± 0.055	1.758ArgLys: 1.758 ± 0.047	7.235ArgLeu: 7.235 ± 0.108	1.784ArgMet: 1.784 ± 0.04	1.339ArgAsn: 1.339 ± 0.031	3.936ArgPro: 3.936 ± 0.078	1.959ArgGln: 1.959 ± 0.044	6.933ArgArg: 6.933 ± 0.111	4.398ArgSer: 4.398 ± 0.063	4.374ArgThr: 4.374 ± 0.06	5.821ArgVal: 5.821 ± 0.075	1.257ArgTrp: 1.257 ± 0.035	1.552ArgTyr: 1.552 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.922SerAla: 6.922 ± 0.087	0.398SerCys: 0.398 ± 0.022	3.554SerAsp: 3.554 ± 0.07	3.156SerGlu: 3.156 ± 0.064	1.713SerPhe: 1.713 ± 0.043	5.905SerGly: 5.905 ± 0.076	1.091SerHis: 1.091 ± 0.036	2.005SerIle: 2.005 ± 0.05	1.59SerLys: 1.59 ± 0.055	5.418SerLeu: 5.418 ± 0.081	1.399SerMet: 1.399 ± 0.042	1.278SerAsn: 1.278 ± 0.041	3.008SerPro: 3.008 ± 0.064	1.436SerGln: 1.436 ± 0.041	3.846SerArg: 3.846 ± 0.067	4.345SerSer: 4.345 ± 0.13	3.775SerThr: 3.775 ± 0.079	4.727SerVal: 4.727 ± 0.079	0.904SerTrp: 0.904 ± 0.035	1.178SerTyr: 1.178 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	6.809ThrAla: 6.809 ± 0.088	0.447ThrCys: 0.447 ± 0.022	3.514ThrAsp: 3.514 ± 0.066	2.827ThrGlu: 2.827 ± 0.058	2.067ThrPhe: 2.067 ± 0.045	5.409ThrGly: 5.409 ± 0.082	1.36ThrHis: 1.36 ± 0.036	2.37ThrIle: 2.37 ± 0.052	1.839ThrLys: 1.839 ± 0.05	5.958ThrLeu: 5.958 ± 0.081	1.268ThrMet: 1.268 ± 0.035	1.458ThrAsn: 1.458 ± 0.041	4.063ThrPro: 4.063 ± 0.064	1.731ThrGln: 1.731 ± 0.045	4.014ThrArg: 4.014 ± 0.073	4.238ThrSer: 4.238 ± 0.08	4.147ThrThr: 4.147 ± 0.088	4.968ThrVal: 4.968 ± 0.07	1.034ThrTrp: 1.034 ± 0.033	1.42ThrTyr: 1.42 ± 0.039	0.0ThrXaa: 0.0 ± 0.0
Val	11.675ValAla: 11.675 ± 0.127	0.684ValCys: 0.684 ± 0.027	5.74ValAsp: 5.74 ± 0.087	5.809ValGlu: 5.809 ± 0.075	2.424ValPhe: 2.424 ± 0.052	7.295ValGly: 7.295 ± 0.103	1.811ValHis: 1.811 ± 0.048	3.596ValIle: 3.596 ± 0.065	2.112ValLys: 2.112 ± 0.054	9.063ValLeu: 9.063 ± 0.119	1.75ValMet: 1.75 ± 0.044	1.73ValAsn: 1.73 ± 0.042	4.567ValPro: 4.567 ± 0.061	1.993ValGln: 1.993 ± 0.044	6.324ValArg: 6.324 ± 0.082	4.882ValSer: 4.882 ± 0.082	6.229ValThr: 6.229 ± 0.094	9.792ValVal: 9.792 ± 0.121	1.125ValTrp: 1.125 ± 0.035	1.375ValTyr: 1.375 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.676TrpAla: 1.676 ± 0.037	0.178TrpCys: 0.178 ± 0.013	0.706TrpAsp: 0.706 ± 0.026	0.677TrpGlu: 0.677 ± 0.027	0.573TrpPhe: 0.573 ± 0.024	1.068TrpGly: 1.068 ± 0.041	0.364TrpHis: 0.364 ± 0.019	0.599TrpIle: 0.599 ± 0.026	0.384TrpLys: 0.384 ± 0.021	1.665TrpLeu: 1.665 ± 0.044	0.355TrpMet: 0.355 ± 0.019	0.468TrpAsn: 0.468 ± 0.026	0.773TrpPro: 0.773 ± 0.029	0.554TrpGln: 0.554 ± 0.023	1.288TrpArg: 1.288 ± 0.04	1.016TrpSer: 1.016 ± 0.034	0.82TrpThr: 0.82 ± 0.03	1.162TrpVal: 1.162 ± 0.035	0.348TrpTrp: 0.348 ± 0.021	0.268TrpTyr: 0.268 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.324TyrAla: 2.324 ± 0.054	0.148TyrCys: 0.148 ± 0.013	1.432TyrAsp: 1.432 ± 0.045	1.252TyrGlu: 1.252 ± 0.037	0.634TyrPhe: 0.634 ± 0.027	1.985TyrGly: 1.985 ± 0.056	0.334TyrHis: 0.334 ± 0.02	0.59TyrIle: 0.59 ± 0.024	0.467TyrLys: 0.467 ± 0.023	1.982TyrLeu: 1.982 ± 0.047	0.285TyrMet: 0.285 ± 0.017	0.411TyrAsn: 0.411 ± 0.022	0.967TyrPro: 0.967 ± 0.037	0.491TyrGln: 0.491 ± 0.023	1.511TyrArg: 1.511 ± 0.04	0.975TyrSer: 0.975 ± 0.036	1.053TyrThr: 1.053 ± 0.038	1.752TyrVal: 1.752 ± 0.041	0.32TyrTrp: 0.32 ± 0.021	0.413TyrTyr: 0.413 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2846 proteins (933200 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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