Amino acid dipepetide frequency for Mosquito VEM Anellovirus SDRB B

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.979AlaAla: 3.979 ± 2.312
0.0AlaCys: 0.0 ± 0.0
1.326AlaAsp: 1.326 ± 0.622
9.284AlaGlu: 9.284 ± 4.357
1.326AlaPhe: 1.326 ± 0.622
1.326AlaGly: 1.326 ± 0.622
0.0AlaHis: 0.0 ± 0.0
1.326AlaIle: 1.326 ± 0.622
3.979AlaLys: 3.979 ± 1.748
7.958AlaLeu: 7.958 ± 5.203
0.0AlaMet: 0.0 ± 0.0
2.653AlaAsn: 2.653 ± 1.243
1.326AlaPro: 1.326 ± 0.622
1.326AlaGln: 1.326 ± 2.43
7.958AlaArg: 7.958 ± 3.73
2.653AlaSer: 2.653 ± 1.243
2.653AlaThr: 2.653 ± 1.243
1.326AlaVal: 1.326 ± 0.622
2.653AlaTrp: 2.653 ± 1.243
1.326AlaTyr: 1.326 ± 0.622
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.326CysPhe: 1.326 ± 0.622
1.326CysGly: 1.326 ± 3.11
1.326CysHis: 1.326 ± 0.622
2.653CysIle: 2.653 ± 1.243
1.326CysLys: 1.326 ± 0.622
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.326CysAsn: 1.326 ± 3.11
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.326CysArg: 1.326 ± 0.622
1.326CysSer: 1.326 ± 0.622
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.979AspAla: 3.979 ± 5.762
0.0AspCys: 0.0 ± 0.0
1.326AspAsp: 1.326 ± 0.622
1.326AspGlu: 1.326 ± 3.11
2.653AspPhe: 2.653 ± 1.243
5.305AspGly: 5.305 ± 2.487
0.0AspHis: 0.0 ± 0.0
5.305AspIle: 5.305 ± 1.67
3.979AspLys: 3.979 ± 1.748
5.305AspLeu: 5.305 ± 2.487
1.326AspMet: 1.326 ± 3.924
0.0AspAsn: 0.0 ± 0.0
2.653AspPro: 2.653 ± 2.669
0.0AspGln: 0.0 ± 0.0
0.0AspArg: 0.0 ± 0.0
3.979AspSer: 3.979 ± 1.865
3.979AspThr: 3.979 ± 1.748
0.0AspVal: 0.0 ± 0.0
1.326AspTrp: 1.326 ± 2.43
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.979GluAla: 3.979 ± 2.312
0.0GluCys: 0.0 ± 0.0
6.631GluAsp: 6.631 ± 2.027
9.284GluGlu: 9.284 ± 4.352
0.0GluPhe: 0.0 ± 0.0
5.305GluGly: 5.305 ± 5.337
1.326GluHis: 1.326 ± 0.622
1.326GluIle: 1.326 ± 0.622
5.305GluLys: 5.305 ± 4.047
3.979GluLeu: 3.979 ± 3.527
0.0GluMet: 0.0 ± 0.0
2.653GluAsn: 2.653 ± 2.023
2.653GluPro: 2.653 ± 1.243
1.326GluGln: 1.326 ± 3.11
5.305GluArg: 5.305 ± 2.487
6.631GluSer: 6.631 ± 7.649
2.653GluThr: 2.653 ± 1.243
1.326GluVal: 1.326 ± 0.622
0.0GluTrp: 0.0 ± 0.0
2.653GluTyr: 2.653 ± 1.243
0.0GluXaa: 0.0 ± 0.0
Phe
2.653PheAla: 2.653 ± 1.243
2.653PheCys: 2.653 ± 2.669
1.326PheAsp: 1.326 ± 0.622
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
1.326PheGly: 1.326 ± 0.622
0.0PheHis: 0.0 ± 0.0
2.653PheIle: 2.653 ± 1.243
0.0PheLys: 0.0 ± 0.0
0.0PheLeu: 0.0 ± 0.0
1.326PheMet: 1.326 ± 0.622
1.326PheAsn: 1.326 ± 0.622
1.326PhePro: 1.326 ± 0.622
2.653PheGln: 2.653 ± 1.243
3.979PheArg: 3.979 ± 2.312
2.653PheSer: 2.653 ± 2.023
0.0PheThr: 0.0 ± 0.0
0.0PheVal: 0.0 ± 0.0
3.979PheTrp: 3.979 ± 1.865
5.305PheTyr: 5.305 ± 2.487
0.0PheXaa: 0.0 ± 0.0
Gly
6.631GlyAla: 6.631 ± 1.815
0.0GlyCys: 0.0 ± 0.0
3.979GlyAsp: 3.979 ± 5.762
2.653GlyGlu: 2.653 ± 2.669
2.653GlyPhe: 2.653 ± 1.243
9.284GlyGly: 9.284 ± 4.357
1.326GlyHis: 1.326 ± 0.622
6.631GlyIle: 6.631 ± 2.027
0.0GlyLys: 0.0 ± 0.0
1.326GlyLeu: 1.326 ± 2.43
1.326GlyMet: 1.326 ± 2.032
1.326GlyAsn: 1.326 ± 0.622
2.653GlyPro: 2.653 ± 1.243
0.0GlyGln: 0.0 ± 0.0
7.958GlyArg: 7.958 ± 3.73
2.653GlySer: 2.653 ± 2.023
7.958GlyThr: 7.958 ± 4.623
3.979GlyVal: 3.979 ± 1.865
2.653GlyTrp: 2.653 ± 2.669
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.326HisAla: 1.326 ± 0.622
0.0HisCys: 0.0 ± 0.0
1.326HisAsp: 1.326 ± 0.622
1.326HisGlu: 1.326 ± 0.622
1.326HisPhe: 1.326 ± 0.622
1.326HisGly: 1.326 ± 0.622
2.653HisHis: 2.653 ± 4.86
1.326HisIle: 1.326 ± 0.622
0.0HisLys: 0.0 ± 0.0
2.653HisLeu: 2.653 ± 2.669
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.653HisPro: 2.653 ± 1.243
2.653HisGln: 2.653 ± 4.146
2.653HisArg: 2.653 ± 1.243
2.653HisSer: 2.653 ± 1.243
0.0HisThr: 0.0 ± 0.0
2.653HisVal: 2.653 ± 1.243
0.0HisTrp: 0.0 ± 0.0
1.326HisTyr: 1.326 ± 0.622
0.0HisXaa: 0.0 ± 0.0
Ile
3.979IleAla: 3.979 ± 1.865
0.0IleCys: 0.0 ± 0.0
1.326IleAsp: 1.326 ± 0.622
2.653IleGlu: 2.653 ± 2.669
3.979IlePhe: 3.979 ± 1.865
2.653IleGly: 2.653 ± 1.243
3.979IleHis: 3.979 ± 1.748
0.0IleIle: 0.0 ± 0.0
3.979IleLys: 3.979 ± 1.865
2.653IleLeu: 2.653 ± 2.669
0.0IleMet: 0.0 ± 0.0
1.326IleAsn: 1.326 ± 0.622
1.326IlePro: 1.326 ± 0.622
1.326IleGln: 1.326 ± 3.11
3.979IleArg: 3.979 ± 1.865
2.653IleSer: 2.653 ± 2.023
5.305IleThr: 5.305 ± 2.487
5.305IleVal: 5.305 ± 2.487
2.653IleTrp: 2.653 ± 2.023
2.653IleTyr: 2.653 ± 1.243
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
1.326LysCys: 1.326 ± 0.622
3.979LysAsp: 3.979 ± 1.748
5.305LysGlu: 5.305 ± 2.909
2.653LysPhe: 2.653 ± 1.243
0.0LysGly: 0.0 ± 0.0
0.0LysHis: 0.0 ± 0.0
1.326LysIle: 1.326 ± 0.622
6.631LysLys: 6.631 ± 3.73
1.326LysLeu: 1.326 ± 0.622
2.653LysMet: 2.653 ± 1.243
0.0LysAsn: 0.0 ± 0.0
6.631LysPro: 6.631 ± 1.815
5.305LysGln: 5.305 ± 5.337
7.958LysArg: 7.958 ± 6.07
1.326LysSer: 1.326 ± 0.622
2.653LysThr: 2.653 ± 4.86
1.326LysVal: 1.326 ± 0.622
2.653LysTrp: 2.653 ± 1.243
2.653LysTyr: 2.653 ± 1.243
0.0LysXaa: 0.0 ± 0.0
Leu
2.653LeuAla: 2.653 ± 1.243
0.0LeuCys: 0.0 ± 0.0
5.305LeuAsp: 5.305 ± 2.083
2.653LeuGlu: 2.653 ± 1.243
5.305LeuPhe: 5.305 ± 5.337
2.653LeuGly: 2.653 ± 1.243
0.0LeuHis: 0.0 ± 0.0
2.653LeuIle: 2.653 ± 2.023
6.631LeuLys: 6.631 ± 2.293
13.263LeuLeu: 13.263 ± 4.174
1.326LeuMet: 1.326 ± 3.11
5.305LeuAsn: 5.305 ± 5.437
5.305LeuPro: 5.305 ± 4.047
3.979LeuGln: 3.979 ± 3.527
3.979LeuArg: 3.979 ± 2.312
2.653LeuSer: 2.653 ± 2.669
1.326LeuThr: 1.326 ± 0.622
5.305LeuVal: 5.305 ± 2.487
1.326LeuTrp: 1.326 ± 0.622
1.326LeuTyr: 1.326 ± 0.622
0.0LeuXaa: 0.0 ± 0.0
Met
2.653MetAla: 2.653 ± 2.669
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
1.326MetPhe: 1.326 ± 0.622
2.653MetGly: 2.653 ± 2.023
0.0MetHis: 0.0 ± 0.0
1.326MetIle: 1.326 ± 0.622
1.326MetLys: 1.326 ± 0.622
2.653MetLeu: 2.653 ± 2.669
1.326MetMet: 1.326 ± 0.622
0.0MetAsn: 0.0 ± 0.0
1.326MetPro: 1.326 ± 0.622
1.326MetGln: 1.326 ± 0.622
0.0MetArg: 0.0 ± 0.0
1.326MetSer: 1.326 ± 3.11
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
1.326AsnCys: 1.326 ± 3.11
0.0AsnAsp: 0.0 ± 0.0
1.326AsnGlu: 1.326 ± 2.43
1.326AsnPhe: 1.326 ± 0.622
3.979AsnGly: 3.979 ± 1.865
0.0AsnHis: 0.0 ± 0.0
1.326AsnIle: 1.326 ± 0.622
1.326AsnLys: 1.326 ± 0.622
2.653AsnLeu: 2.653 ± 2.023
0.0AsnMet: 0.0 ± 0.0
6.631AsnAsn: 6.631 ± 3.108
0.0AsnPro: 0.0 ± 0.0
1.326AsnGln: 1.326 ± 0.622
2.653AsnArg: 2.653 ± 1.243
1.326AsnSer: 1.326 ± 0.622
3.979AsnThr: 3.979 ± 1.865
5.305AsnVal: 5.305 ± 1.67
1.326AsnTrp: 1.326 ± 0.622
1.326AsnTyr: 1.326 ± 3.11
0.0AsnXaa: 0.0 ± 0.0
Pro
2.653ProAla: 2.653 ± 1.243
0.0ProCys: 0.0 ± 0.0
2.653ProAsp: 2.653 ± 2.669
1.326ProGlu: 1.326 ± 0.622
2.653ProPhe: 2.653 ± 2.023
3.979ProGly: 3.979 ± 2.312
2.653ProHis: 2.653 ± 1.243
2.653ProIle: 2.653 ± 1.243
1.326ProLys: 1.326 ± 0.622
9.284ProLeu: 9.284 ± 3.655
1.326ProMet: 1.326 ± 0.622
2.653ProAsn: 2.653 ± 1.243
3.979ProPro: 3.979 ± 1.865
5.305ProGln: 5.305 ± 4.047
1.326ProArg: 1.326 ± 0.622
5.305ProSer: 5.305 ± 2.487
5.305ProThr: 5.305 ± 2.487
1.326ProVal: 1.326 ± 0.622
2.653ProTrp: 2.653 ± 1.243
1.326ProTyr: 1.326 ± 0.622
1.326ProXaa: 1.326 ± 2.43
Gln
0.0GlnAla: 0.0 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
3.979GlnGlu: 3.979 ± 4.429
0.0GlnPhe: 0.0 ± 0.0
3.979GlnGly: 3.979 ± 5.762
2.653GlnHis: 2.653 ± 1.243
3.979GlnIle: 3.979 ± 2.312
5.305GlnLys: 5.305 ± 2.909
5.305GlnLeu: 5.305 ± 2.083
0.0GlnMet: 0.0 ± 0.0
2.653GlnAsn: 2.653 ± 1.243
5.305GlnPro: 5.305 ± 2.487
5.305GlnGln: 5.305 ± 5.437
2.653GlnArg: 2.653 ± 2.023
2.653GlnSer: 2.653 ± 2.023
1.326GlnThr: 1.326 ± 3.11
1.326GlnVal: 1.326 ± 3.11
1.326GlnTrp: 1.326 ± 0.622
2.653GlnTyr: 2.653 ± 1.243
0.0GlnXaa: 0.0 ± 0.0
Arg
5.305ArgAla: 5.305 ± 1.67
0.0ArgCys: 0.0 ± 0.0
3.979ArgAsp: 3.979 ± 1.748
3.979ArgGlu: 3.979 ± 1.748
1.326ArgPhe: 1.326 ± 0.622
1.326ArgGly: 1.326 ± 0.622
3.979ArgHis: 3.979 ± 2.312
5.305ArgIle: 5.305 ± 2.487
9.284ArgLys: 9.284 ± 2.574
5.305ArgLeu: 5.305 ± 2.083
0.0ArgMet: 0.0 ± 0.0
1.326ArgAsn: 1.326 ± 0.622
2.653ArgPro: 2.653 ± 1.243
6.631ArgGln: 6.631 ± 2.027
29.178ArgArg: 29.178 ± 6.437
1.326ArgSer: 1.326 ± 2.43
7.958ArgThr: 7.958 ± 1.682
1.326ArgVal: 1.326 ± 0.622
2.653ArgTrp: 2.653 ± 1.243
7.958ArgTyr: 7.958 ± 3.73
0.0ArgXaa: 0.0 ± 0.0
Ser
3.979SerAla: 3.979 ± 1.865
0.0SerCys: 0.0 ± 0.0
5.305SerAsp: 5.305 ± 4.047
3.979SerGlu: 3.979 ± 3.527
0.0SerPhe: 0.0 ± 0.0
5.305SerGly: 5.305 ± 4.047
5.305SerHis: 5.305 ± 2.083
3.979SerIle: 3.979 ± 3.527
0.0SerLys: 0.0 ± 0.0
5.305SerLeu: 5.305 ± 1.67
1.326SerMet: 1.326 ± 0.622
2.653SerAsn: 2.653 ± 1.243
1.326SerPro: 1.326 ± 2.43
2.653SerGln: 2.653 ± 1.243
1.326SerArg: 1.326 ± 0.622
10.61SerSer: 10.61 ± 8.093
9.284SerThr: 9.284 ± 3.362
2.653SerVal: 2.653 ± 1.243
1.326SerTrp: 1.326 ± 0.622
2.653SerTyr: 2.653 ± 1.243
0.0SerXaa: 0.0 ± 0.0
Thr
2.653ThrAla: 2.653 ± 2.023
1.326ThrCys: 1.326 ± 0.622
2.653ThrAsp: 2.653 ± 2.023
7.958ThrGlu: 7.958 ± 2.139
1.326ThrPhe: 1.326 ± 0.622
5.305ThrGly: 5.305 ± 5.337
0.0ThrHis: 0.0 ± 0.0
2.653ThrIle: 2.653 ± 1.243
1.326ThrLys: 1.326 ± 0.622
1.326ThrLeu: 1.326 ± 0.622
1.326ThrMet: 1.326 ± 0.622
1.326ThrAsn: 1.326 ± 0.622
7.958ThrPro: 7.958 ± 5.203
5.305ThrGln: 5.305 ± 2.487
6.631ThrArg: 6.631 ± 3.73
5.305ThrSer: 5.305 ± 2.487
7.958ThrThr: 7.958 ± 4.241
3.979ThrVal: 3.979 ± 1.865
0.0ThrTrp: 0.0 ± 0.0
2.653ThrTyr: 2.653 ± 1.243
0.0ThrXaa: 0.0 ± 0.0
Val
3.979ValAla: 3.979 ± 1.865
2.653ValCys: 2.653 ± 1.243
2.653ValAsp: 2.653 ± 1.243
2.653ValGlu: 2.653 ± 1.243
1.326ValPhe: 1.326 ± 0.622
0.0ValGly: 0.0 ± 0.0
0.0ValHis: 0.0 ± 0.0
1.326ValIle: 1.326 ± 0.622
1.326ValLys: 1.326 ± 0.622
2.653ValLeu: 2.653 ± 1.243
1.326ValMet: 1.326 ± 0.618
1.326ValAsn: 1.326 ± 0.622
3.979ValPro: 3.979 ± 1.748
2.653ValGln: 2.653 ± 1.243
2.653ValArg: 2.653 ± 2.669
2.653ValSer: 2.653 ± 1.243
2.653ValThr: 2.653 ± 1.243
0.0ValVal: 0.0 ± 0.0
2.653ValTrp: 2.653 ± 1.243
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.326TrpAla: 1.326 ± 0.622
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.653TrpGlu: 2.653 ± 1.243
1.326TrpPhe: 1.326 ± 0.622
2.653TrpGly: 2.653 ± 1.243
1.326TrpHis: 1.326 ± 0.622
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.326TrpMet: 1.326 ± 0.622
1.326TrpAsn: 1.326 ± 0.622
5.305TrpPro: 5.305 ± 2.487
0.0TrpGln: 0.0 ± 0.0
6.631TrpArg: 6.631 ± 2.027
5.305TrpSer: 5.305 ± 4.047
1.326TrpThr: 1.326 ± 0.622
1.326TrpVal: 1.326 ± 0.622
2.653TrpTrp: 2.653 ± 1.243
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.653TyrAla: 2.653 ± 1.243
2.653TyrCys: 2.653 ± 1.243
0.0TyrAsp: 0.0 ± 0.0
0.0TyrGlu: 0.0 ± 0.0
1.326TyrPhe: 1.326 ± 0.622
5.305TyrGly: 5.305 ± 2.487
1.326TyrHis: 1.326 ± 0.622
3.979TyrIle: 3.979 ± 1.865
1.326TyrLys: 1.326 ± 3.11
0.0TyrLeu: 0.0 ± 0.0
0.0TyrMet: 0.0 ± 0.0
1.326TyrAsn: 1.326 ± 0.622
2.653TyrPro: 2.653 ± 1.243
1.326TyrGln: 1.326 ± 0.622
2.653TyrArg: 2.653 ± 1.243
3.979TyrSer: 3.979 ± 1.865
2.653TyrThr: 2.653 ± 1.243
0.0TyrVal: 0.0 ± 0.0
2.653TyrTrp: 2.653 ± 1.243
7.958TyrTyr: 7.958 ± 3.73
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
1.326XaaLys: 1.326 ± 2.43
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (755 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski