Amino acid dipepetide frequency for Wenzhou picorna-like virus 43

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.355AlaAla: 9.355 ± 0.0
2.339AlaCys: 2.339 ± 0.0
5.145AlaAsp: 5.145 ± 0.0
4.677AlaGlu: 4.677 ± 0.0
2.806AlaPhe: 2.806 ± 0.0
7.016AlaGly: 7.016 ± 0.0
2.339AlaHis: 2.339 ± 0.0
2.339AlaIle: 2.339 ± 0.0
2.339AlaLys: 2.339 ± 0.0
9.355AlaLeu: 9.355 ± 0.0
3.742AlaMet: 3.742 ± 0.0
1.403AlaAsn: 1.403 ± 0.0
2.339AlaPro: 2.339 ± 0.0
7.951AlaGln: 7.951 ± 0.0
4.21AlaArg: 4.21 ± 0.0
6.08AlaSer: 6.08 ± 0.0
6.08AlaThr: 6.08 ± 0.0
8.887AlaVal: 8.887 ± 0.0
0.468AlaTrp: 0.468 ± 0.0
2.339AlaTyr: 2.339 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.468CysAla: 0.468 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.935CysAsp: 0.935 ± 0.0
0.468CysGlu: 0.468 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.403CysGly: 1.403 ± 0.0
0.468CysHis: 0.468 ± 0.0
1.871CysIle: 1.871 ± 0.0
0.468CysLys: 0.468 ± 0.0
0.935CysLeu: 0.935 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.468CysAsn: 0.468 ± 0.0
0.468CysPro: 0.468 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.403CysArg: 1.403 ± 0.0
0.468CysSer: 0.468 ± 0.0
0.468CysThr: 0.468 ± 0.0
0.468CysVal: 0.468 ± 0.0
0.935CysTrp: 0.935 ± 0.0
0.935CysTyr: 0.935 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.339AspAla: 2.339 ± 0.0
0.468AspCys: 0.468 ± 0.0
2.806AspAsp: 2.806 ± 0.0
3.274AspGlu: 3.274 ± 0.0
2.339AspPhe: 2.339 ± 0.0
3.742AspGly: 3.742 ± 0.0
0.468AspHis: 0.468 ± 0.0
5.145AspIle: 5.145 ± 0.0
2.339AspLys: 2.339 ± 0.0
5.145AspLeu: 5.145 ± 0.0
2.339AspMet: 2.339 ± 0.0
2.339AspAsn: 2.339 ± 0.0
3.274AspPro: 3.274 ± 0.0
0.935AspGln: 0.935 ± 0.0
2.339AspArg: 2.339 ± 0.0
5.145AspSer: 5.145 ± 0.0
0.935AspThr: 0.935 ± 0.0
4.21AspVal: 4.21 ± 0.0
0.0AspTrp: 0.0 ± 0.0
5.145AspTyr: 5.145 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.274GluAla: 3.274 ± 0.0
0.0GluCys: 0.0 ± 0.0
0.935GluAsp: 0.935 ± 0.0
2.806GluGlu: 2.806 ± 0.0
2.339GluPhe: 2.339 ± 0.0
2.339GluGly: 2.339 ± 0.0
2.339GluHis: 2.339 ± 0.0
2.339GluIle: 2.339 ± 0.0
2.339GluLys: 2.339 ± 0.0
3.274GluLeu: 3.274 ± 0.0
1.871GluMet: 1.871 ± 0.0
1.871GluAsn: 1.871 ± 0.0
1.871GluPro: 1.871 ± 0.0
2.339GluGln: 2.339 ± 0.0
2.339GluArg: 2.339 ± 0.0
2.339GluSer: 2.339 ± 0.0
1.871GluThr: 1.871 ± 0.0
6.08GluVal: 6.08 ± 0.0
0.935GluTrp: 0.935 ± 0.0
1.871GluTyr: 1.871 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
4.21PheAla: 4.21 ± 0.0
0.0PheCys: 0.0 ± 0.0
2.339PheAsp: 2.339 ± 0.0
1.403PheGlu: 1.403 ± 0.0
0.468PhePhe: 0.468 ± 0.0
3.274PheGly: 3.274 ± 0.0
0.468PheHis: 0.468 ± 0.0
1.871PheIle: 1.871 ± 0.0
1.871PheLys: 1.871 ± 0.0
4.21PheLeu: 4.21 ± 0.0
0.935PheMet: 0.935 ± 0.0
1.871PheAsn: 1.871 ± 0.0
2.339PhePro: 2.339 ± 0.0
0.468PheGln: 0.468 ± 0.0
1.403PheArg: 1.403 ± 0.0
2.339PheSer: 2.339 ± 0.0
3.274PheThr: 3.274 ± 0.0
1.403PheVal: 1.403 ± 0.0
0.935PheTrp: 0.935 ± 0.0
1.871PheTyr: 1.871 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
7.016GlyAla: 7.016 ± 0.0
0.468GlyCys: 0.468 ± 0.0
4.677GlyAsp: 4.677 ± 0.0
3.742GlyGlu: 3.742 ± 0.0
1.871GlyPhe: 1.871 ± 0.0
7.016GlyGly: 7.016 ± 0.0
0.468GlyHis: 0.468 ± 0.0
5.145GlyIle: 5.145 ± 0.0
2.339GlyLys: 2.339 ± 0.0
8.887GlyLeu: 8.887 ± 0.0
2.806GlyMet: 2.806 ± 0.0
0.935GlyAsn: 0.935 ± 0.0
4.677GlyPro: 4.677 ± 0.0
3.274GlyGln: 3.274 ± 0.0
6.08GlyArg: 6.08 ± 0.0
6.548GlySer: 6.548 ± 0.0
3.274GlyThr: 3.274 ± 0.0
6.548GlyVal: 6.548 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
1.871GlyTyr: 1.871 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.339HisAla: 2.339 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.871HisAsp: 1.871 ± 0.0
1.403HisGlu: 1.403 ± 0.0
1.403HisPhe: 1.403 ± 0.0
2.806HisGly: 2.806 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.935HisIle: 0.935 ± 0.0
0.468HisLys: 0.468 ± 0.0
2.806HisLeu: 2.806 ± 0.0
0.468HisMet: 0.468 ± 0.0
0.468HisAsn: 0.468 ± 0.0
0.0HisPro: 0.0 ± 0.0
2.806HisGln: 2.806 ± 0.0
1.403HisArg: 1.403 ± 0.0
1.403HisSer: 1.403 ± 0.0
1.871HisThr: 1.871 ± 0.0
1.871HisVal: 1.871 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.468HisTyr: 0.468 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.613IleAla: 5.613 ± 0.0
0.935IleCys: 0.935 ± 0.0
0.935IleAsp: 0.935 ± 0.0
1.871IleGlu: 1.871 ± 0.0
1.403IlePhe: 1.403 ± 0.0
2.339IleGly: 2.339 ± 0.0
2.339IleHis: 2.339 ± 0.0
0.935IleIle: 0.935 ± 0.0
2.806IleLys: 2.806 ± 0.0
2.806IleLeu: 2.806 ± 0.0
2.339IleMet: 2.339 ± 0.0
1.871IleAsn: 1.871 ± 0.0
5.145IlePro: 5.145 ± 0.0
1.403IleGln: 1.403 ± 0.0
1.403IleArg: 1.403 ± 0.0
4.21IleSer: 4.21 ± 0.0
3.742IleThr: 3.742 ± 0.0
4.677IleVal: 4.677 ± 0.0
0.468IleTrp: 0.468 ± 0.0
1.871IleTyr: 1.871 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.274LysAla: 3.274 ± 0.0
0.0LysCys: 0.0 ± 0.0
2.339LysAsp: 2.339 ± 0.0
1.403LysGlu: 1.403 ± 0.0
2.339LysPhe: 2.339 ± 0.0
1.871LysGly: 1.871 ± 0.0
0.935LysHis: 0.935 ± 0.0
3.742LysIle: 3.742 ± 0.0
4.677LysLys: 4.677 ± 0.0
1.403LysLeu: 1.403 ± 0.0
0.935LysMet: 0.935 ± 0.0
2.339LysAsn: 2.339 ± 0.0
2.339LysPro: 2.339 ± 0.0
1.871LysGln: 1.871 ± 0.0
1.871LysArg: 1.871 ± 0.0
2.806LysSer: 2.806 ± 0.0
3.742LysThr: 3.742 ± 0.0
2.806LysVal: 2.806 ± 0.0
0.0LysTrp: 0.0 ± 0.0
2.339LysTyr: 2.339 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
8.419LeuAla: 8.419 ± 0.0
1.403LeuCys: 1.403 ± 0.0
5.613LeuAsp: 5.613 ± 0.0
2.806LeuGlu: 2.806 ± 0.0
3.274LeuPhe: 3.274 ± 0.0
4.677LeuGly: 4.677 ± 0.0
4.677LeuHis: 4.677 ± 0.0
0.935LeuIle: 0.935 ± 0.0
2.339LeuLys: 2.339 ± 0.0
4.21LeuLeu: 4.21 ± 0.0
2.339LeuMet: 2.339 ± 0.0
5.145LeuAsn: 5.145 ± 0.0
4.677LeuPro: 4.677 ± 0.0
1.871LeuGln: 1.871 ± 0.0
3.274LeuArg: 3.274 ± 0.0
7.484LeuSer: 7.484 ± 0.0
5.145LeuThr: 5.145 ± 0.0
9.822LeuVal: 9.822 ± 0.0
0.468LeuTrp: 0.468 ± 0.0
1.403LeuTyr: 1.403 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
4.677MetAla: 4.677 ± 0.0
0.0MetCys: 0.0 ± 0.0
1.403MetAsp: 1.403 ± 0.0
0.935MetGlu: 0.935 ± 0.0
0.935MetPhe: 0.935 ± 0.0
1.871MetGly: 1.871 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.935MetIle: 0.935 ± 0.0
1.403MetLys: 1.403 ± 0.0
1.403MetLeu: 1.403 ± 0.0
0.468MetMet: 0.468 ± 0.0
0.468MetAsn: 0.468 ± 0.0
0.935MetPro: 0.935 ± 0.0
0.935MetGln: 0.935 ± 0.0
2.339MetArg: 2.339 ± 0.0
1.403MetSer: 1.403 ± 0.0
2.339MetThr: 2.339 ± 0.0
2.339MetVal: 2.339 ± 0.0
0.935MetTrp: 0.935 ± 0.0
0.935MetTyr: 0.935 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.806AsnAla: 2.806 ± 0.0
0.468AsnCys: 0.468 ± 0.0
2.339AsnAsp: 2.339 ± 0.0
1.403AsnGlu: 1.403 ± 0.0
0.935AsnPhe: 0.935 ± 0.0
1.403AsnGly: 1.403 ± 0.0
0.935AsnHis: 0.935 ± 0.0
2.339AsnIle: 2.339 ± 0.0
1.871AsnLys: 1.871 ± 0.0
3.742AsnLeu: 3.742 ± 0.0
0.468AsnMet: 0.468 ± 0.0
1.403AsnAsn: 1.403 ± 0.0
4.677AsnPro: 4.677 ± 0.0
0.935AsnGln: 0.935 ± 0.0
1.871AsnArg: 1.871 ± 0.0
1.871AsnSer: 1.871 ± 0.0
5.145AsnThr: 5.145 ± 0.0
4.677AsnVal: 4.677 ± 0.0
0.468AsnTrp: 0.468 ± 0.0
2.806AsnTyr: 2.806 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.21ProAla: 4.21 ± 0.0
1.871ProCys: 1.871 ± 0.0
3.742ProAsp: 3.742 ± 0.0
0.935ProGlu: 0.935 ± 0.0
1.403ProPhe: 1.403 ± 0.0
3.742ProGly: 3.742 ± 0.0
1.403ProHis: 1.403 ± 0.0
2.806ProIle: 2.806 ± 0.0
1.403ProLys: 1.403 ± 0.0
2.806ProLeu: 2.806 ± 0.0
0.935ProMet: 0.935 ± 0.0
1.871ProAsn: 1.871 ± 0.0
0.935ProPro: 0.935 ± 0.0
3.742ProGln: 3.742 ± 0.0
3.742ProArg: 3.742 ± 0.0
2.806ProSer: 2.806 ± 0.0
3.742ProThr: 3.742 ± 0.0
4.21ProVal: 4.21 ± 0.0
0.0ProTrp: 0.0 ± 0.0
1.871ProTyr: 1.871 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.677GlnAla: 4.677 ± 0.0
0.468GlnCys: 0.468 ± 0.0
1.403GlnAsp: 1.403 ± 0.0
1.871GlnGlu: 1.871 ± 0.0
2.339GlnPhe: 2.339 ± 0.0
6.548GlnGly: 6.548 ± 0.0
0.0GlnHis: 0.0 ± 0.0
1.871GlnIle: 1.871 ± 0.0
0.935GlnLys: 0.935 ± 0.0
2.806GlnLeu: 2.806 ± 0.0
0.468GlnMet: 0.468 ± 0.0
3.742GlnAsn: 3.742 ± 0.0
0.468GlnPro: 0.468 ± 0.0
0.935GlnGln: 0.935 ± 0.0
0.0GlnArg: 0.0 ± 0.0
2.339GlnSer: 2.339 ± 0.0
1.403GlnThr: 1.403 ± 0.0
3.742GlnVal: 3.742 ± 0.0
0.468GlnTrp: 0.468 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.145ArgAla: 5.145 ± 0.0
1.403ArgCys: 1.403 ± 0.0
4.677ArgAsp: 4.677 ± 0.0
4.21ArgGlu: 4.21 ± 0.0
0.935ArgPhe: 0.935 ± 0.0
2.339ArgGly: 2.339 ± 0.0
0.935ArgHis: 0.935 ± 0.0
0.935ArgIle: 0.935 ± 0.0
0.935ArgLys: 0.935 ± 0.0
7.016ArgLeu: 7.016 ± 0.0
2.806ArgMet: 2.806 ± 0.0
0.468ArgAsn: 0.468 ± 0.0
3.274ArgPro: 3.274 ± 0.0
0.935ArgGln: 0.935 ± 0.0
2.806ArgArg: 2.806 ± 0.0
3.274ArgSer: 3.274 ± 0.0
2.339ArgThr: 2.339 ± 0.0
4.677ArgVal: 4.677 ± 0.0
0.0ArgTrp: 0.0 ± 0.0
1.403ArgTyr: 1.403 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
6.08SerAla: 6.08 ± 0.0
1.403SerCys: 1.403 ± 0.0
1.871SerAsp: 1.871 ± 0.0
3.274SerGlu: 3.274 ± 0.0
3.274SerPhe: 3.274 ± 0.0
7.016SerGly: 7.016 ± 0.0
0.935SerHis: 0.935 ± 0.0
2.806SerIle: 2.806 ± 0.0
4.677SerLys: 4.677 ± 0.0
7.951SerLeu: 7.951 ± 0.0
0.468SerMet: 0.468 ± 0.0
3.742SerAsn: 3.742 ± 0.0
2.806SerPro: 2.806 ± 0.0
0.935SerGln: 0.935 ± 0.0
1.871SerArg: 1.871 ± 0.0
5.145SerSer: 5.145 ± 0.0
6.08SerThr: 6.08 ± 0.0
8.887SerVal: 8.887 ± 0.0
0.468SerTrp: 0.468 ± 0.0
3.274SerTyr: 3.274 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.613ThrAla: 5.613 ± 0.0
0.468ThrCys: 0.468 ± 0.0
2.339ThrAsp: 2.339 ± 0.0
3.274ThrGlu: 3.274 ± 0.0
2.806ThrPhe: 2.806 ± 0.0
8.419ThrGly: 8.419 ± 0.0
2.806ThrHis: 2.806 ± 0.0
4.677ThrIle: 4.677 ± 0.0
3.274ThrLys: 3.274 ± 0.0
2.806ThrLeu: 2.806 ± 0.0
1.403ThrMet: 1.403 ± 0.0
4.21ThrAsn: 4.21 ± 0.0
2.339ThrPro: 2.339 ± 0.0
1.871ThrGln: 1.871 ± 0.0
2.806ThrArg: 2.806 ± 0.0
5.613ThrSer: 5.613 ± 0.0
6.548ThrThr: 6.548 ± 0.0
5.613ThrVal: 5.613 ± 0.0
0.468ThrTrp: 0.468 ± 0.0
1.871ThrTyr: 1.871 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
7.951ValAla: 7.951 ± 0.0
0.468ValCys: 0.468 ± 0.0
6.548ValAsp: 6.548 ± 0.0
5.145ValGlu: 5.145 ± 0.0
3.274ValPhe: 3.274 ± 0.0
7.016ValGly: 7.016 ± 0.0
1.871ValHis: 1.871 ± 0.0
5.613ValIle: 5.613 ± 0.0
2.806ValLys: 2.806 ± 0.0
7.016ValLeu: 7.016 ± 0.0
1.403ValMet: 1.403 ± 0.0
6.08ValAsn: 6.08 ± 0.0
4.21ValPro: 4.21 ± 0.0
0.935ValGln: 0.935 ± 0.0
7.016ValArg: 7.016 ± 0.0
7.016ValSer: 7.016 ± 0.0
5.613ValThr: 5.613 ± 0.0
7.951ValVal: 7.951 ± 0.0
0.0ValTrp: 0.0 ± 0.0
4.21ValTyr: 4.21 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.468TrpCys: 0.468 ± 0.0
0.468TrpAsp: 0.468 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.468TrpPhe: 0.468 ± 0.0
0.468TrpGly: 0.468 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.468TrpIle: 0.468 ± 0.0
1.403TrpLys: 1.403 ± 0.0
0.468TrpLeu: 0.468 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.468TrpAsn: 0.468 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.935TrpGln: 0.935 ± 0.0
0.468TrpArg: 0.468 ± 0.0
0.935TrpSer: 0.935 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.742TyrAla: 3.742 ± 0.0
0.0TyrCys: 0.0 ± 0.0
2.339TyrAsp: 2.339 ± 0.0
0.935TyrGlu: 0.935 ± 0.0
2.339TyrPhe: 2.339 ± 0.0
2.339TyrGly: 2.339 ± 0.0
1.403TyrHis: 1.403 ± 0.0
1.403TyrIle: 1.403 ± 0.0
2.339TyrLys: 2.339 ± 0.0
0.935TyrLeu: 0.935 ± 0.0
0.0TyrMet: 0.0 ± 0.0
1.403TyrAsn: 1.403 ± 0.0
1.403TyrPro: 1.403 ± 0.0
1.403TyrGln: 1.403 ± 0.0
1.871TyrArg: 1.871 ± 0.0
3.742TyrSer: 3.742 ± 0.0
5.613TyrThr: 5.613 ± 0.0
3.274TyrVal: 3.274 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
2.339TyrTyr: 2.339 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2139 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski