Amino acid dipepetide frequency for Shuangao sobemo-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.728AlaAla: 6.728 ± 1.481
2.523AlaCys: 2.523 ± 0.0
5.887AlaAsp: 5.887 ± 0.74
1.682AlaGlu: 1.682 ± 0.37
0.841AlaPhe: 0.841 ± 0.371
6.728AlaGly: 6.728 ± 0.742
1.682AlaHis: 1.682 ± 0.37
6.728AlaIle: 6.728 ± 0.742
3.364AlaLys: 3.364 ± 0.371
4.205AlaLeu: 4.205 ± 0.37
1.682AlaMet: 1.682 ± 0.37
0.841AlaAsn: 0.841 ± 0.371
1.682AlaPro: 1.682 ± 0.741
0.841AlaGln: 0.841 ± 0.741
3.364AlaArg: 3.364 ± 0.74
3.364AlaSer: 3.364 ± 0.371
5.887AlaThr: 5.887 ± 1.483
5.046AlaVal: 5.046 ± 2.224
1.682AlaTrp: 1.682 ± 0.37
2.523AlaTyr: 2.523 ± 1.111
0.0AlaXaa: 0.0 ± 0.0
Cys
0.841CysAla: 0.841 ± 0.741
0.841CysCys: 0.841 ± 0.371
0.841CysAsp: 0.841 ± 0.741
0.841CysGlu: 0.841 ± 0.371
0.841CysPhe: 0.841 ± 0.741
2.523CysGly: 2.523 ± 1.112
0.841CysHis: 0.841 ± 0.741
0.841CysIle: 0.841 ± 0.371
0.841CysLys: 0.841 ± 0.371
1.682CysLeu: 1.682 ± 0.741
0.0CysMet: 0.0 ± 0.0
4.205CysAsn: 4.205 ± 0.37
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.841CysArg: 0.841 ± 0.741
0.841CysSer: 0.841 ± 0.371
2.523CysThr: 2.523 ± 1.111
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.841CysTyr: 0.841 ± 0.741
0.0CysXaa: 0.0 ± 0.0
Asp
3.364AspAla: 3.364 ± 0.74
0.841AspCys: 0.841 ± 0.371
4.205AspAsp: 4.205 ± 1.481
1.682AspGlu: 1.682 ± 0.741
1.682AspPhe: 1.682 ± 0.37
1.682AspGly: 1.682 ± 1.481
0.841AspHis: 0.841 ± 0.741
3.364AspIle: 3.364 ± 0.74
0.841AspLys: 0.841 ± 0.741
4.205AspLeu: 4.205 ± 1.853
0.841AspMet: 0.841 ± 0.741
0.841AspAsn: 0.841 ± 0.371
2.523AspPro: 2.523 ± 0.0
2.523AspGln: 2.523 ± 0.0
5.046AspArg: 5.046 ± 0.001
3.364AspSer: 3.364 ± 0.371
4.205AspThr: 4.205 ± 0.742
0.841AspVal: 0.841 ± 0.371
3.364AspTrp: 3.364 ± 0.74
1.682AspTyr: 1.682 ± 0.741
0.0AspXaa: 0.0 ± 0.0
Glu
5.887GluAla: 5.887 ± 0.372
0.0GluCys: 0.0 ± 0.0
1.682GluAsp: 1.682 ± 0.741
9.251GluGlu: 9.251 ± 0.743
0.841GluPhe: 0.841 ± 0.741
5.046GluGly: 5.046 ± 2.222
0.841GluHis: 0.841 ± 0.371
7.569GluIle: 7.569 ± 1.113
5.887GluLys: 5.887 ± 0.74
5.046GluLeu: 5.046 ± 0.001
0.841GluMet: 0.841 ± 0.335
1.682GluAsn: 1.682 ± 0.741
3.364GluPro: 3.364 ± 2.963
4.205GluGln: 4.205 ± 0.37
4.205GluArg: 4.205 ± 1.481
1.682GluSer: 1.682 ± 0.741
3.364GluThr: 3.364 ± 1.852
2.523GluVal: 2.523 ± 1.112
0.841GluTrp: 0.841 ± 0.371
1.682GluTyr: 1.682 ± 0.37
0.0GluXaa: 0.0 ± 0.0
Phe
2.523PheAla: 2.523 ± 0.0
0.0PheCys: 0.0 ± 0.0
3.364PheAsp: 3.364 ± 0.74
0.0PheGlu: 0.0 ± 0.0
0.841PhePhe: 0.841 ± 0.741
1.682PheGly: 1.682 ± 0.37
0.841PheHis: 0.841 ± 0.371
1.682PheIle: 1.682 ± 0.37
0.0PheLys: 0.0 ± 0.0
3.364PheLeu: 3.364 ± 0.371
0.0PheMet: 0.0 ± 0.0
0.841PheAsn: 0.841 ± 0.741
0.841PhePro: 0.841 ± 0.741
0.0PheGln: 0.0 ± 0.0
3.364PheArg: 3.364 ± 0.74
0.0PheSer: 0.0 ± 0.0
0.841PheThr: 0.841 ± 0.741
3.364PheVal: 3.364 ± 0.74
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.887GlyAla: 5.887 ± 0.372
0.0GlyCys: 0.0 ± 0.0
1.682GlyAsp: 1.682 ± 0.37
0.841GlyGlu: 0.841 ± 0.741
1.682GlyPhe: 1.682 ± 0.37
3.364GlyGly: 3.364 ± 2.963
0.0GlyHis: 0.0 ± 0.0
5.046GlyIle: 5.046 ± 1.11
1.682GlyLys: 1.682 ± 0.741
8.41GlyLeu: 8.41 ± 1.851
1.682GlyMet: 1.682 ± 0.37
1.682GlyAsn: 1.682 ± 0.741
5.046GlyPro: 5.046 ± 1.112
4.205GlyGln: 4.205 ± 0.742
5.887GlyArg: 5.887 ± 0.74
4.205GlySer: 4.205 ± 1.853
5.887GlyThr: 5.887 ± 1.483
3.364GlyVal: 3.364 ± 0.371
4.205GlyTrp: 4.205 ± 1.481
5.046GlyTyr: 5.046 ± 1.112
0.0GlyXaa: 0.0 ± 0.0
His
4.205HisAla: 4.205 ± 1.481
0.841HisCys: 0.841 ± 0.371
0.0HisAsp: 0.0 ± 0.0
0.841HisGlu: 0.841 ± 0.371
2.523HisPhe: 2.523 ± 1.111
1.682HisGly: 1.682 ± 0.37
0.0HisHis: 0.0 ± 0.0
2.523HisIle: 2.523 ± 1.111
1.682HisLys: 1.682 ± 0.37
1.682HisLeu: 1.682 ± 0.741
0.841HisMet: 0.841 ± 0.371
0.841HisAsn: 0.841 ± 0.371
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.682HisArg: 1.682 ± 0.37
0.841HisSer: 0.841 ± 0.371
2.523HisThr: 2.523 ± 1.112
2.523HisVal: 2.523 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.841HisTyr: 0.841 ± 0.371
0.0HisXaa: 0.0 ± 0.0
Ile
5.046IleAla: 5.046 ± 1.112
0.0IleCys: 0.0 ± 0.0
2.523IleAsp: 2.523 ± 1.111
3.364IleGlu: 3.364 ± 1.852
0.841IlePhe: 0.841 ± 0.741
3.364IleGly: 3.364 ± 0.371
4.205IleHis: 4.205 ± 1.853
5.046IleIle: 5.046 ± 1.11
3.364IleLys: 3.364 ± 1.852
2.523IleLeu: 2.523 ± 0.0
2.523IleMet: 2.523 ± 1.112
1.682IleAsn: 1.682 ± 0.37
5.887IlePro: 5.887 ± 0.372
2.523IleGln: 2.523 ± 0.0
7.569IleArg: 7.569 ± 2.221
5.046IleSer: 5.046 ± 0.001
2.523IleThr: 2.523 ± 1.111
2.523IleVal: 2.523 ± 0.0
0.841IleTrp: 0.841 ± 0.741
1.682IleTyr: 1.682 ± 0.37
0.0IleXaa: 0.0 ± 0.0
Lys
3.364LysAla: 3.364 ± 0.371
1.682LysCys: 1.682 ± 0.741
0.0LysAsp: 0.0 ± 0.0
5.046LysGlu: 5.046 ± 1.11
1.682LysPhe: 1.682 ± 1.481
2.523LysGly: 2.523 ± 0.0
0.841LysHis: 0.841 ± 0.741
2.523LysIle: 2.523 ± 1.111
1.682LysLys: 1.682 ± 0.37
3.364LysLeu: 3.364 ± 1.482
2.523LysMet: 2.523 ± 0.383
0.0LysAsn: 0.0 ± 0.0
3.364LysPro: 3.364 ± 0.74
0.841LysGln: 0.841 ± 0.371
5.046LysArg: 5.046 ± 1.112
1.682LysSer: 1.682 ± 0.37
2.523LysThr: 2.523 ± 1.112
3.364LysVal: 3.364 ± 0.74
1.682LysTrp: 1.682 ± 0.37
1.682LysTyr: 1.682 ± 0.741
0.0LysXaa: 0.0 ± 0.0
Leu
5.046LeuAla: 5.046 ± 1.11
1.682LeuCys: 1.682 ± 0.37
1.682LeuAsp: 1.682 ± 0.37
9.251LeuGlu: 9.251 ± 1.48
3.364LeuPhe: 3.364 ± 0.74
6.728LeuGly: 6.728 ± 1.854
3.364LeuHis: 3.364 ± 0.74
1.682LeuIle: 1.682 ± 0.37
1.682LeuLys: 1.682 ± 0.37
6.728LeuLeu: 6.728 ± 2.592
1.682LeuMet: 1.682 ± 0.741
2.523LeuAsn: 2.523 ± 1.112
4.205LeuPro: 4.205 ± 0.742
5.887LeuGln: 5.887 ± 0.372
5.887LeuArg: 5.887 ± 0.372
5.046LeuSer: 5.046 ± 0.001
2.523LeuThr: 2.523 ± 0.0
5.887LeuVal: 5.887 ± 2.594
1.682LeuTrp: 1.682 ± 0.741
5.046LeuTyr: 5.046 ± 1.11
0.0LeuXaa: 0.0 ± 0.0
Met
2.523MetAla: 2.523 ± 1.111
0.0MetCys: 0.0 ± 0.0
1.682MetAsp: 1.682 ± 0.741
1.682MetGlu: 1.682 ± 0.37
0.0MetPhe: 0.0 ± 0.0
1.682MetGly: 1.682 ± 1.481
0.0MetHis: 0.0 ± 0.0
1.682MetIle: 1.682 ± 0.37
0.0MetLys: 0.0 ± 0.0
1.682MetLeu: 1.682 ± 0.37
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.682MetPro: 1.682 ± 0.741
1.682MetGln: 1.682 ± 0.741
0.841MetArg: 0.841 ± 0.741
1.682MetSer: 1.682 ± 0.741
1.682MetThr: 1.682 ± 0.37
3.364MetVal: 3.364 ± 0.371
0.0MetTrp: 0.0 ± 0.0
0.841MetTyr: 0.841 ± 0.371
0.0MetXaa: 0.0 ± 0.0
Asn
3.364AsnAla: 3.364 ± 0.371
1.682AsnCys: 1.682 ± 0.37
0.841AsnAsp: 0.841 ± 0.371
4.205AsnGlu: 4.205 ± 1.481
0.0AsnPhe: 0.0 ± 0.0
1.682AsnGly: 1.682 ± 0.37
0.0AsnHis: 0.0 ± 0.0
1.682AsnIle: 1.682 ± 1.481
0.0AsnLys: 0.0 ± 0.0
0.841AsnLeu: 0.841 ± 0.371
0.841AsnMet: 0.841 ± 0.741
1.682AsnAsn: 1.682 ± 0.741
2.523AsnPro: 2.523 ± 1.112
1.682AsnGln: 1.682 ± 0.741
2.523AsnArg: 2.523 ± 0.0
2.523AsnSer: 2.523 ± 0.0
3.364AsnThr: 3.364 ± 1.482
0.841AsnVal: 0.841 ± 0.371
0.841AsnTrp: 0.841 ± 0.741
0.841AsnTyr: 0.841 ± 0.371
0.0AsnXaa: 0.0 ± 0.0
Pro
1.682ProAla: 1.682 ± 0.37
0.841ProCys: 0.841 ± 0.741
0.841ProAsp: 0.841 ± 0.741
3.364ProGlu: 3.364 ± 0.371
0.841ProPhe: 0.841 ± 0.371
4.205ProGly: 4.205 ± 0.37
0.841ProHis: 0.841 ± 0.371
1.682ProIle: 1.682 ± 0.37
5.046ProLys: 5.046 ± 0.001
5.887ProLeu: 5.887 ± 0.74
0.841ProMet: 0.841 ± 0.371
1.682ProAsn: 1.682 ± 0.741
11.775ProPro: 11.775 ± 2.966
3.364ProGln: 3.364 ± 0.371
3.364ProArg: 3.364 ± 0.371
3.364ProSer: 3.364 ± 1.482
4.205ProThr: 4.205 ± 1.853
4.205ProVal: 4.205 ± 0.742
0.841ProTrp: 0.841 ± 0.741
2.523ProTyr: 2.523 ± 1.111
0.0ProXaa: 0.0 ± 0.0
Gln
0.841GlnAla: 0.841 ± 0.371
0.841GlnCys: 0.841 ± 0.371
5.046GlnAsp: 5.046 ± 1.112
0.841GlnGlu: 0.841 ± 0.371
0.841GlnPhe: 0.841 ± 0.371
1.682GlnGly: 1.682 ± 0.741
0.841GlnHis: 0.841 ± 0.741
2.523GlnIle: 2.523 ± 1.111
2.523GlnLys: 2.523 ± 1.112
2.523GlnLeu: 2.523 ± 2.222
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
3.364GlnPro: 3.364 ± 0.371
0.841GlnGln: 0.841 ± 0.741
5.046GlnArg: 5.046 ± 2.224
3.364GlnSer: 3.364 ± 1.482
4.205GlnThr: 4.205 ± 0.742
3.364GlnVal: 3.364 ± 1.482
0.841GlnTrp: 0.841 ± 0.741
2.523GlnTyr: 2.523 ± 1.111
0.0GlnXaa: 0.0 ± 0.0
Arg
0.841ArgAla: 0.841 ± 0.371
0.841ArgCys: 0.841 ± 0.371
4.205ArgAsp: 4.205 ± 0.742
3.364ArgGlu: 3.364 ± 0.74
1.682ArgPhe: 1.682 ± 0.741
3.364ArgGly: 3.364 ± 0.371
1.682ArgHis: 1.682 ± 0.37
4.205ArgIle: 4.205 ± 0.742
5.046ArgLys: 5.046 ± 1.112
5.887ArgLeu: 5.887 ± 0.74
2.523ArgMet: 2.523 ± 0.0
5.046ArgAsn: 5.046 ± 1.11
4.205ArgPro: 4.205 ± 0.742
3.364ArgGln: 3.364 ± 0.371
3.364ArgArg: 3.364 ± 1.482
5.887ArgSer: 5.887 ± 0.74
7.569ArgThr: 7.569 ± 0.001
5.046ArgVal: 5.046 ± 1.112
0.0ArgTrp: 0.0 ± 0.0
3.364ArgTyr: 3.364 ± 1.852
0.0ArgXaa: 0.0 ± 0.0
Ser
5.046SerAla: 5.046 ± 1.112
2.523SerCys: 2.523 ± 0.0
2.523SerAsp: 2.523 ± 0.0
3.364SerGlu: 3.364 ± 0.371
0.841SerPhe: 0.841 ± 0.741
6.728SerGly: 6.728 ± 0.742
0.841SerHis: 0.841 ± 0.371
3.364SerIle: 3.364 ± 0.74
1.682SerLys: 1.682 ± 0.741
3.364SerLeu: 3.364 ± 1.482
0.841SerMet: 0.841 ± 0.741
0.0SerAsn: 0.0 ± 0.0
2.523SerPro: 2.523 ± 0.0
3.364SerGln: 3.364 ± 0.371
3.364SerArg: 3.364 ± 1.482
3.364SerSer: 3.364 ± 0.74
5.887SerThr: 5.887 ± 1.483
9.251SerVal: 9.251 ± 0.743
1.682SerTrp: 1.682 ± 0.741
1.682SerTyr: 1.682 ± 0.37
0.0SerXaa: 0.0 ± 0.0
Thr
1.682ThrAla: 1.682 ± 0.741
2.523ThrCys: 2.523 ± 1.111
4.205ThrAsp: 4.205 ± 1.853
3.364ThrGlu: 3.364 ± 0.74
0.841ThrPhe: 0.841 ± 0.371
3.364ThrGly: 3.364 ± 1.482
3.364ThrHis: 3.364 ± 0.74
5.887ThrIle: 5.887 ± 1.483
2.523ThrLys: 2.523 ± 0.0
9.251ThrLeu: 9.251 ± 0.369
1.682ThrMet: 1.682 ± 0.741
5.046ThrAsn: 5.046 ± 3.333
4.205ThrPro: 4.205 ± 0.37
2.523ThrGln: 2.523 ± 1.112
4.205ThrArg: 4.205 ± 1.853
5.046ThrSer: 5.046 ± 0.001
5.887ThrThr: 5.887 ± 0.74
4.205ThrVal: 4.205 ± 0.37
1.682ThrTrp: 1.682 ± 0.741
0.841ThrTyr: 0.841 ± 0.371
0.0ThrXaa: 0.0 ± 0.0
Val
6.728ValAla: 6.728 ± 1.854
1.682ValCys: 1.682 ± 1.481
2.523ValAsp: 2.523 ± 1.111
7.569ValGlu: 7.569 ± 1.113
0.841ValPhe: 0.841 ± 0.371
5.887ValGly: 5.887 ± 0.372
3.364ValHis: 3.364 ± 1.482
1.682ValIle: 1.682 ± 0.37
3.364ValLys: 3.364 ± 0.74
5.887ValLeu: 5.887 ± 2.594
0.0ValMet: 0.0 ± 0.0
1.682ValAsn: 1.682 ± 0.741
3.364ValPro: 3.364 ± 1.482
2.523ValGln: 2.523 ± 1.112
4.205ValArg: 4.205 ± 1.853
5.887ValSer: 5.887 ± 1.483
4.205ValThr: 4.205 ± 1.481
5.046ValVal: 5.046 ± 0.001
0.841ValTrp: 0.841 ± 0.371
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.841TrpAla: 0.841 ± 0.371
0.0TrpCys: 0.0 ± 0.0
1.682TrpAsp: 1.682 ± 1.481
0.841TrpGlu: 0.841 ± 0.741
0.841TrpPhe: 0.841 ± 0.371
1.682TrpGly: 1.682 ± 0.741
0.0TrpHis: 0.0 ± 0.0
1.682TrpIle: 1.682 ± 0.37
2.523TrpLys: 2.523 ± 0.0
1.682TrpLeu: 1.682 ± 1.481
2.523TrpMet: 2.523 ± 1.111
1.682TrpAsn: 1.682 ± 0.741
0.0TrpPro: 0.0 ± 0.0
0.841TrpGln: 0.841 ± 0.371
0.0TrpArg: 0.0 ± 0.0
3.364TrpSer: 3.364 ± 0.74
0.841TrpThr: 0.841 ± 0.371
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.841TyrAla: 0.841 ± 0.371
0.841TyrCys: 0.841 ± 0.741
2.523TyrAsp: 2.523 ± 1.112
5.887TyrGlu: 5.887 ± 0.372
1.682TyrPhe: 1.682 ± 0.37
4.205TyrGly: 4.205 ± 0.37
1.682TyrHis: 1.682 ± 0.37
1.682TyrIle: 1.682 ± 0.37
1.682TyrLys: 1.682 ± 0.37
3.364TyrLeu: 3.364 ± 0.371
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
0.841TyrPro: 0.841 ± 0.741
0.841TyrGln: 0.841 ± 0.741
1.682TyrArg: 1.682 ± 0.37
1.682TyrSer: 1.682 ± 0.37
1.682TyrThr: 1.682 ± 1.481
2.523TyrVal: 2.523 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
2.523TyrTyr: 2.523 ± 1.112
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1190 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski