Amino acid dipepetide frequency for Acholeplasma phage MV-L51

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
0.0AlaCys: 0.0 ± 0.0
1.381AlaAsp: 1.381 ± 1.274
0.0AlaGlu: 0.0 ± 0.0
1.381AlaPhe: 1.381 ± 1.274
2.762AlaGly: 2.762 ± 2.141
0.0AlaHis: 0.0 ± 0.0
9.669AlaIle: 9.669 ± 1.582
4.144AlaLys: 4.144 ± 2.486
6.906AlaLeu: 6.906 ± 2.632
1.381AlaMet: 1.381 ± 1.228
0.0AlaAsn: 0.0 ± 0.0
0.0AlaPro: 0.0 ± 0.0
2.762AlaGln: 2.762 ± 2.141
1.381AlaArg: 1.381 ± 1.07
1.381AlaSer: 1.381 ± 1.631
4.144AlaThr: 4.144 ± 2.051
2.762AlaVal: 2.762 ± 1.309
0.0AlaTrp: 0.0 ± 0.0
4.144AlaTyr: 4.144 ± 2.301
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.381CysIle: 1.381 ± 1.631
0.0CysLys: 0.0 ± 0.0
1.381CysLeu: 1.381 ± 1.631
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.381CysPro: 1.381 ± 1.07
1.381CysGln: 1.381 ± 1.07
0.0CysArg: 0.0 ± 0.0
1.381CysSer: 1.381 ± 1.07
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.381CysTyr: 1.381 ± 1.274
0.0CysXaa: 0.0 ± 0.0
Asp
1.381AspAla: 1.381 ± 1.274
0.0AspCys: 0.0 ± 0.0
0.0AspAsp: 0.0 ± 0.0
0.0AspGlu: 0.0 ± 0.0
1.381AspPhe: 1.381 ± 1.274
2.762AspGly: 2.762 ± 1.57
0.0AspHis: 0.0 ± 0.0
1.381AspIle: 1.381 ± 1.228
1.381AspLys: 1.381 ± 1.07
4.144AspLeu: 4.144 ± 1.42
1.381AspMet: 1.381 ± 1.274
0.0AspAsn: 0.0 ± 0.0
0.0AspPro: 0.0 ± 0.0
1.381AspGln: 1.381 ± 1.631
1.381AspArg: 1.381 ± 1.228
2.762AspSer: 2.762 ± 1.57
4.144AspThr: 4.144 ± 2.301
2.762AspVal: 2.762 ± 2.141
0.0AspTrp: 0.0 ± 0.0
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
1.381GluAla: 1.381 ± 1.07
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
0.0GluGlu: 0.0 ± 0.0
1.381GluPhe: 1.381 ± 1.07
2.762GluGly: 2.762 ± 2.141
1.381GluHis: 1.381 ± 1.631
4.144GluIle: 4.144 ± 2.135
0.0GluLys: 0.0 ± 0.0
2.762GluLeu: 2.762 ± 2.141
0.0GluMet: 0.0 ± 0.0
4.144GluAsn: 4.144 ± 1.42
1.381GluPro: 1.381 ± 1.228
1.381GluGln: 1.381 ± 1.07
2.762GluArg: 2.762 ± 2.141
1.381GluSer: 1.381 ± 1.07
0.0GluThr: 0.0 ± 0.0
1.381GluVal: 1.381 ± 1.274
0.0GluTrp: 0.0 ± 0.0
4.144GluTyr: 4.144 ± 3.38
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.381PheCys: 1.381 ± 1.07
0.0PheAsp: 0.0 ± 0.0
2.762PheGlu: 2.762 ± 2.141
1.381PhePhe: 1.381 ± 1.07
1.381PheGly: 1.381 ± 1.07
2.762PheHis: 2.762 ± 1.06
12.431PheIle: 12.431 ± 6.254
2.762PheLys: 2.762 ± 2.548
2.762PheLeu: 2.762 ± 1.06
0.0PheMet: 0.0 ± 0.0
2.762PheAsn: 2.762 ± 2.141
0.0PhePro: 0.0 ± 0.0
1.381PheGln: 1.381 ± 1.07
2.762PheArg: 2.762 ± 2.548
2.762PheSer: 2.762 ± 1.49
8.287PheThr: 8.287 ± 2.015
2.762PheVal: 2.762 ± 1.965
1.381PheTrp: 1.381 ± 1.274
1.381PheTyr: 1.381 ± 1.07
0.0PheXaa: 0.0 ± 0.0
Gly
2.762GlyAla: 2.762 ± 1.06
0.0GlyCys: 0.0 ± 0.0
0.0GlyAsp: 0.0 ± 0.0
1.381GlyGlu: 1.381 ± 1.07
0.0GlyPhe: 0.0 ± 0.0
0.0GlyGly: 0.0 ± 0.0
1.381GlyHis: 1.381 ± 1.274
5.525GlyIle: 5.525 ± 2.617
2.762GlyLys: 2.762 ± 1.965
6.906GlyLeu: 6.906 ± 3.656
2.762GlyMet: 2.762 ± 1.57
0.0GlyAsn: 0.0 ± 0.0
0.0GlyPro: 0.0 ± 0.0
6.906GlyGln: 6.906 ± 3.27
1.381GlyArg: 1.381 ± 1.07
4.144GlySer: 4.144 ± 0.882
0.0GlyThr: 0.0 ± 0.0
1.381GlyVal: 1.381 ± 1.228
0.0GlyTrp: 0.0 ± 0.0
4.144GlyTyr: 4.144 ± 2.727
0.0GlyXaa: 0.0 ± 0.0
His
1.381HisAla: 1.381 ± 1.228
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.381HisPhe: 1.381 ± 1.631
0.0HisGly: 0.0 ± 0.0
4.144HisHis: 4.144 ± 3.38
4.144HisIle: 4.144 ± 2.085
6.906HisLys: 6.906 ± 2.632
1.381HisLeu: 1.381 ± 1.07
0.0HisMet: 0.0 ± 0.0
2.762HisAsn: 2.762 ± 1.881
0.0HisPro: 0.0 ± 0.0
1.381HisGln: 1.381 ± 1.631
0.0HisArg: 0.0 ± 0.0
1.381HisSer: 1.381 ± 1.228
1.381HisThr: 1.381 ± 1.631
0.0HisVal: 0.0 ± 0.0
2.762HisTrp: 2.762 ± 1.309
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.525IleAla: 5.525 ± 2.98
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
5.525IleGlu: 5.525 ± 1.57
11.05IlePhe: 11.05 ± 4.875
2.762IleGly: 2.762 ± 1.309
6.906IleHis: 6.906 ± 2.202
12.431IleIle: 12.431 ± 2.805
13.812IleLys: 13.812 ± 5.184
8.287IleLeu: 8.287 ± 3.082
8.287IleMet: 8.287 ± 4.029
11.05IleAsn: 11.05 ± 3.67
1.381IlePro: 1.381 ± 1.07
4.144IleGln: 4.144 ± 1.42
1.381IleArg: 1.381 ± 1.07
1.381IleSer: 1.381 ± 1.631
6.906IleThr: 6.906 ± 2.359
4.144IleVal: 4.144 ± 1.42
0.0IleTrp: 0.0 ± 0.0
8.287IleTyr: 8.287 ± 3.912
0.0IleXaa: 0.0 ± 0.0
Lys
2.762LysAla: 2.762 ± 2.141
1.381LysCys: 1.381 ± 1.07
6.906LysAsp: 6.906 ± 1.712
4.144LysGlu: 4.144 ± 1.707
2.762LysPhe: 2.762 ± 1.06
1.381LysGly: 1.381 ± 1.228
4.144LysHis: 4.144 ± 3.211
6.906LysIle: 6.906 ± 3.27
6.906LysLys: 6.906 ± 1.514
6.906LysLeu: 6.906 ± 1.902
2.762LysMet: 2.762 ± 2.25
4.144LysAsn: 4.144 ± 1.707
0.0LysPro: 0.0 ± 0.0
12.431LysGln: 12.431 ± 4.866
4.144LysArg: 4.144 ± 0.882
6.906LysSer: 6.906 ± 1.902
2.762LysThr: 2.762 ± 1.309
1.381LysVal: 1.381 ± 1.274
0.0LysTrp: 0.0 ± 0.0
9.669LysTyr: 9.669 ± 2.536
0.0LysXaa: 0.0 ± 0.0
Leu
2.762LeuAla: 2.762 ± 1.309
1.381LeuCys: 1.381 ± 1.274
4.144LeuAsp: 4.144 ± 1.707
2.762LeuGlu: 2.762 ± 1.57
2.762LeuPhe: 2.762 ± 1.309
2.762LeuGly: 2.762 ± 1.49
0.0LeuHis: 0.0 ± 0.0
13.812LeuIle: 13.812 ± 4.852
9.669LeuLys: 9.669 ± 2.46
11.05LeuLeu: 11.05 ± 2.24
2.762LeuMet: 2.762 ± 1.685
2.762LeuAsn: 2.762 ± 1.57
5.525LeuPro: 5.525 ± 2.645
2.762LeuGln: 2.762 ± 1.06
4.144LeuArg: 4.144 ± 3.211
5.525LeuSer: 5.525 ± 3.289
5.525LeuThr: 5.525 ± 1.275
4.144LeuVal: 4.144 ± 1.707
1.381LeuTrp: 1.381 ± 1.631
11.05LeuTyr: 11.05 ± 5.153
0.0LeuXaa: 0.0 ± 0.0
Met
2.762MetAla: 2.762 ± 1.309
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
2.762MetGlu: 2.762 ± 1.965
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
2.762MetIle: 2.762 ± 1.49
4.144MetLys: 4.144 ± 0.882
4.144MetLeu: 4.144 ± 3.018
0.0MetMet: 0.0 ± 0.0
1.381MetAsn: 1.381 ± 1.274
0.0MetPro: 0.0 ± 0.0
1.381MetGln: 1.381 ± 1.631
0.0MetArg: 0.0 ± 0.0
1.381MetSer: 1.381 ± 1.274
2.762MetThr: 2.762 ± 1.965
1.381MetVal: 1.381 ± 1.228
0.0MetTrp: 0.0 ± 0.0
1.381MetTyr: 1.381 ± 1.07
0.0MetXaa: 0.0 ± 0.0
Asn
8.287AsnAla: 8.287 ± 0.888
0.0AsnCys: 0.0 ± 0.0
1.381AsnAsp: 1.381 ± 1.631
5.525AsnGlu: 5.525 ± 3.14
1.381AsnPhe: 1.381 ± 1.07
0.0AsnGly: 0.0 ± 0.0
0.0AsnHis: 0.0 ± 0.0
4.144AsnIle: 4.144 ± 1.956
8.287AsnLys: 8.287 ± 3.199
2.762AsnLeu: 2.762 ± 1.57
2.762AsnMet: 2.762 ± 1.984
5.525AsnAsn: 5.525 ± 3.28
0.0AsnPro: 0.0 ± 0.0
2.762AsnGln: 2.762 ± 1.881
4.144AsnArg: 4.144 ± 3.38
4.144AsnSer: 4.144 ± 1.707
2.762AsnThr: 2.762 ± 1.881
2.762AsnVal: 2.762 ± 1.309
0.0AsnTrp: 0.0 ± 0.0
5.525AsnTyr: 5.525 ± 1.021
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
0.0ProGlu: 0.0 ± 0.0
4.144ProPhe: 4.144 ± 1.707
0.0ProGly: 0.0 ± 0.0
0.0ProHis: 0.0 ± 0.0
1.381ProIle: 1.381 ± 1.07
1.381ProLys: 1.381 ± 1.07
1.381ProLeu: 1.381 ± 1.228
0.0ProMet: 0.0 ± 0.0
1.381ProAsn: 1.381 ± 1.07
1.381ProPro: 1.381 ± 1.07
1.381ProGln: 1.381 ± 1.228
0.0ProArg: 0.0 ± 0.0
0.0ProSer: 0.0 ± 0.0
0.0ProThr: 0.0 ± 0.0
2.762ProVal: 2.762 ± 2.141
1.381ProTrp: 1.381 ± 1.07
1.381ProTyr: 1.381 ± 1.228
0.0ProXaa: 0.0 ± 0.0
Gln
1.381GlnAla: 1.381 ± 1.07
1.381GlnCys: 1.381 ± 1.631
1.381GlnAsp: 1.381 ± 1.07
1.381GlnGlu: 1.381 ± 1.07
1.381GlnPhe: 1.381 ± 1.07
8.287GlnGly: 8.287 ± 3.099
1.381GlnHis: 1.381 ± 1.631
2.762GlnIle: 2.762 ± 1.881
4.144GlnLys: 4.144 ± 2.051
5.525GlnLeu: 5.525 ± 1.758
0.0GlnMet: 0.0 ± 0.0
2.762GlnAsn: 2.762 ± 2.141
1.381GlnPro: 1.381 ± 1.228
5.525GlnGln: 5.525 ± 2.617
2.762GlnArg: 2.762 ± 1.965
8.287GlnSer: 8.287 ± 4.225
8.287GlnThr: 8.287 ± 2.847
5.525GlnVal: 5.525 ± 3.658
0.0GlnTrp: 0.0 ± 0.0
4.144GlnTyr: 4.144 ± 3.685
0.0GlnXaa: 0.0 ± 0.0
Arg
2.762ArgAla: 2.762 ± 1.309
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
0.0ArgGlu: 0.0 ± 0.0
2.762ArgPhe: 2.762 ± 2.548
4.144ArgGly: 4.144 ± 1.707
1.381ArgHis: 1.381 ± 1.631
6.906ArgIle: 6.906 ± 1.902
1.381ArgLys: 1.381 ± 1.07
2.762ArgLeu: 2.762 ± 2.548
0.0ArgMet: 0.0 ± 0.0
2.762ArgAsn: 2.762 ± 1.57
1.381ArgPro: 1.381 ± 1.07
0.0ArgGln: 0.0 ± 0.0
1.381ArgArg: 1.381 ± 1.274
2.762ArgSer: 2.762 ± 1.57
1.381ArgThr: 1.381 ± 1.07
1.381ArgVal: 1.381 ± 1.228
0.0ArgTrp: 0.0 ± 0.0
1.381ArgTyr: 1.381 ± 1.07
0.0ArgXaa: 0.0 ± 0.0
Ser
4.144SerAla: 4.144 ± 1.549
1.381SerCys: 1.381 ± 1.631
1.381SerAsp: 1.381 ± 1.07
2.762SerGlu: 2.762 ± 1.309
8.287SerPhe: 8.287 ± 3.179
1.381SerGly: 1.381 ± 1.228
0.0SerHis: 0.0 ± 0.0
5.525SerIle: 5.525 ± 3.28
6.906SerLys: 6.906 ± 3.537
9.669SerLeu: 9.669 ± 5.357
1.381SerMet: 1.381 ± 1.228
4.144SerAsn: 4.144 ± 3.301
1.381SerPro: 1.381 ± 1.228
4.144SerGln: 4.144 ± 1.42
1.381SerArg: 1.381 ± 1.07
2.762SerSer: 2.762 ± 1.965
5.525SerThr: 5.525 ± 2.98
0.0SerVal: 0.0 ± 0.0
1.381SerTrp: 1.381 ± 1.274
4.144SerTyr: 4.144 ± 2.301
0.0SerXaa: 0.0 ± 0.0
Thr
4.144ThrAla: 4.144 ± 3.211
0.0ThrCys: 0.0 ± 0.0
2.762ThrAsp: 2.762 ± 1.881
0.0ThrGlu: 0.0 ± 0.0
1.381ThrPhe: 1.381 ± 1.228
1.381ThrGly: 1.381 ± 1.228
1.381ThrHis: 1.381 ± 1.07
5.525ThrIle: 5.525 ± 1.758
9.669ThrLys: 9.669 ± 2.068
5.525ThrLeu: 5.525 ± 1.021
0.0ThrMet: 0.0 ± 0.0
2.762ThrAsn: 2.762 ± 2.457
2.762ThrPro: 2.762 ± 2.141
8.287ThrGln: 8.287 ± 4.831
0.0ThrArg: 0.0 ± 0.0
9.669ThrSer: 9.669 ± 5.685
6.906ThrThr: 6.906 ± 3.023
2.762ThrVal: 2.762 ± 1.881
1.381ThrTrp: 1.381 ± 1.274
2.762ThrTyr: 2.762 ± 1.309
0.0ThrXaa: 0.0 ± 0.0
Val
1.381ValAla: 1.381 ± 1.07
1.381ValCys: 1.381 ± 1.07
0.0ValAsp: 0.0 ± 0.0
0.0ValGlu: 0.0 ± 0.0
2.762ValPhe: 2.762 ± 1.06
4.144ValGly: 4.144 ± 0.882
1.381ValHis: 1.381 ± 1.228
4.144ValIle: 4.144 ± 1.707
2.762ValLys: 2.762 ± 1.309
5.525ValLeu: 5.525 ± 1.275
0.0ValMet: 0.0 ± 0.0
2.762ValAsn: 2.762 ± 3.263
0.0ValPro: 0.0 ± 0.0
2.762ValGln: 2.762 ± 1.06
0.0ValArg: 0.0 ± 0.0
1.381ValSer: 1.381 ± 1.274
4.144ValThr: 4.144 ± 2.416
1.381ValVal: 1.381 ± 1.274
2.762ValTrp: 2.762 ± 1.06
2.762ValTyr: 2.762 ± 1.881
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.381TrpGly: 1.381 ± 1.274
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
2.762TrpLeu: 2.762 ± 1.309
0.0TrpMet: 0.0 ± 0.0
2.762TrpAsn: 2.762 ± 1.06
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.381TrpArg: 1.381 ± 1.274
2.762TrpSer: 2.762 ± 1.965
0.0TrpThr: 0.0 ± 0.0
1.381TrpVal: 1.381 ± 1.07
1.381TrpTrp: 1.381 ± 1.274
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.381TyrAla: 1.381 ± 1.274
0.0TyrCys: 0.0 ± 0.0
6.906TyrAsp: 6.906 ± 2.359
1.381TyrGlu: 1.381 ± 1.07
5.525TyrPhe: 5.525 ± 2.195
4.144TyrGly: 4.144 ± 1.707
2.762TyrHis: 2.762 ± 1.881
8.287TyrIle: 8.287 ± 2.854
1.381TyrLys: 1.381 ± 1.631
4.144TyrLeu: 4.144 ± 2.085
1.381TyrMet: 1.381 ± 1.105
9.669TyrAsn: 9.669 ± 2.147
0.0TyrPro: 0.0 ± 0.0
5.525TyrGln: 5.525 ± 4.913
4.144TyrArg: 4.144 ± 1.42
5.525TyrSer: 5.525 ± 1.858
4.144TyrThr: 4.144 ± 2.416
1.381TyrVal: 1.381 ± 1.07
0.0TyrTrp: 0.0 ± 0.0
2.762TyrTyr: 2.762 ± 1.309
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (725 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski