Amino acid dipepetide frequency for Simian T-lymphotropic virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.839AlaAla: 5.839 ± 2.009
1.46AlaCys: 1.46 ± 0.438
0.487AlaAsp: 0.487 ± 0.285
1.946AlaGlu: 1.946 ± 0.562
1.46AlaPhe: 1.46 ± 0.737
3.406AlaGly: 3.406 ± 0.816
1.46AlaHis: 1.46 ± 0.438
5.353AlaIle: 5.353 ± 1.518
1.46AlaLys: 1.46 ± 1.472
13.625AlaLeu: 13.625 ± 2.702
0.487AlaMet: 0.487 ± 0.285
1.46AlaAsn: 1.46 ± 1.387
6.813AlaPro: 6.813 ± 1.43
3.406AlaGln: 3.406 ± 1.375
1.46AlaArg: 1.46 ± 0.737
6.326AlaSer: 6.326 ± 1.383
1.46AlaThr: 1.46 ± 0.856
2.92AlaVal: 2.92 ± 0.803
1.46AlaTrp: 1.46 ± 1.387
2.92AlaTyr: 2.92 ± 0.748
0.0AlaXaa: 0.0 ± 0.0
Cys
0.487CysAla: 0.487 ± 0.285
0.973CysCys: 0.973 ± 0.571
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.46CysPhe: 1.46 ± 0.438
1.946CysGly: 1.946 ± 0.785
2.433CysHis: 2.433 ± 0.501
1.46CysIle: 1.46 ± 0.856
0.487CysLys: 0.487 ± 0.285
3.406CysLeu: 3.406 ± 1.276
0.0CysMet: 0.0 ± 0.0
0.973CysAsn: 0.973 ± 0.886
4.38CysPro: 4.38 ± 0.814
2.92CysGln: 2.92 ± 1.484
0.973CysArg: 0.973 ± 0.571
1.46CysSer: 1.46 ± 0.438
1.946CysThr: 1.946 ± 0.61
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.433AspAla: 2.433 ± 0.741
1.46AspCys: 1.46 ± 1.387
0.487AspAsp: 0.487 ± 0.285
0.0AspGlu: 0.0 ± 0.0
0.973AspPhe: 0.973 ± 0.417
1.46AspGly: 1.46 ± 1.388
1.946AspHis: 1.946 ± 0.933
1.946AspIle: 1.946 ± 0.61
2.433AspLys: 2.433 ± 0.846
4.38AspLeu: 4.38 ± 1.616
0.973AspMet: 0.973 ± 0.417
1.46AspAsn: 1.46 ± 0.438
6.326AspPro: 6.326 ± 3.053
1.46AspGln: 1.46 ± 0.856
0.487AspArg: 0.487 ± 0.285
2.433AspSer: 2.433 ± 1.395
1.946AspThr: 1.946 ± 1.93
0.487AspVal: 0.487 ± 0.285
0.0AspTrp: 0.0 ± 0.0
0.487AspTyr: 0.487 ± 0.285
0.0AspXaa: 0.0 ± 0.0
Glu
3.893GluAla: 3.893 ± 0.536
0.487GluCys: 0.487 ± 0.565
0.973GluAsp: 0.973 ± 0.967
1.946GluGlu: 1.946 ± 1.934
0.0GluPhe: 0.0 ± 0.0
0.487GluGly: 0.487 ± 0.565
0.487GluHis: 0.487 ± 0.975
1.946GluIle: 1.946 ± 1.85
0.973GluLys: 0.973 ± 1.529
2.433GluLeu: 2.433 ± 0.951
0.0GluMet: 0.0 ± 0.0
1.46GluAsn: 1.46 ± 0.884
4.866GluPro: 4.866 ± 2.848
0.973GluGln: 0.973 ± 0.571
1.46GluArg: 1.46 ± 0.438
0.487GluSer: 0.487 ± 0.285
2.433GluThr: 2.433 ± 0.923
2.92GluVal: 2.92 ± 0.748
0.0GluTrp: 0.0 ± 0.0
0.973GluTyr: 0.973 ± 0.967
0.0GluXaa: 0.0 ± 0.0
Phe
0.487PheAla: 0.487 ± 0.565
0.973PheCys: 0.973 ± 0.648
0.973PheAsp: 0.973 ± 0.417
0.487PheGlu: 0.487 ± 0.764
0.487PhePhe: 0.487 ± 0.285
0.0PheGly: 0.0 ± 0.0
1.946PheHis: 1.946 ± 2.381
0.973PheIle: 0.973 ± 0.648
1.946PheLys: 1.946 ± 0.969
5.353PheLeu: 5.353 ± 1.057
0.487PheMet: 0.487 ± 0.565
1.46PheAsn: 1.46 ± 0.647
2.92PhePro: 2.92 ± 0.928
3.406PheGln: 3.406 ± 1.384
1.946PheArg: 1.946 ± 1.907
3.893PheSer: 3.893 ± 1.151
1.946PheThr: 1.946 ± 0.761
0.487PheVal: 0.487 ± 0.565
0.487PheTrp: 0.487 ± 0.285
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.866GlyAla: 4.866 ± 0.877
0.487GlyCys: 0.487 ± 0.285
2.433GlyAsp: 2.433 ± 0.859
1.46GlyGlu: 1.46 ± 0.438
0.487GlyPhe: 0.487 ± 0.285
3.406GlyGly: 3.406 ± 0.524
1.946GlyHis: 1.946 ± 1.508
1.946GlyIle: 1.946 ± 0.61
1.46GlyLys: 1.46 ± 0.438
10.706GlyLeu: 10.706 ± 2.071
0.487GlyMet: 0.487 ± 0.285
0.0GlyAsn: 0.0 ± 0.0
4.38GlyPro: 4.38 ± 1.458
4.38GlyGln: 4.38 ± 2.399
2.433GlyArg: 2.433 ± 1.716
2.433GlySer: 2.433 ± 0.806
2.92GlyThr: 2.92 ± 0.59
0.973GlyVal: 0.973 ± 0.886
0.487GlyTrp: 0.487 ± 0.285
2.433GlyTyr: 2.433 ± 0.923
0.0GlyXaa: 0.0 ± 0.0
His
1.946HisAla: 1.946 ± 0.61
1.46HisCys: 1.46 ± 0.856
0.0HisAsp: 0.0 ± 0.0
0.973HisGlu: 0.973 ± 0.648
1.946HisPhe: 1.946 ± 0.933
1.946HisGly: 1.946 ± 0.562
2.92HisHis: 2.92 ± 0.876
2.92HisIle: 2.92 ± 1.106
2.433HisLys: 2.433 ± 0.951
3.406HisLeu: 3.406 ± 1.276
0.0HisMet: 0.0 ± 0.0
1.46HisAsn: 1.46 ± 0.647
3.406HisPro: 3.406 ± 1.839
1.46HisGln: 1.46 ± 0.951
0.973HisArg: 0.973 ± 0.417
3.893HisSer: 3.893 ± 1.69
2.92HisThr: 2.92 ± 0.876
2.92HisVal: 2.92 ± 1.18
2.433HisTrp: 2.433 ± 1.356
0.973HisTyr: 0.973 ± 0.571
0.0HisXaa: 0.0 ± 0.0
Ile
2.433IleAla: 2.433 ± 1.123
0.973IleCys: 0.973 ± 0.417
0.973IleAsp: 0.973 ± 0.571
0.0IleGlu: 0.0 ± 0.0
1.946IlePhe: 1.946 ± 1.443
1.46IleGly: 1.46 ± 0.92
0.487IleHis: 0.487 ± 0.285
1.946IleIle: 1.946 ± 0.933
1.46IleLys: 1.46 ± 0.438
10.219IleLeu: 10.219 ± 1.992
0.0IleMet: 0.0 ± 0.0
2.92IleAsn: 2.92 ± 1.106
4.866IlePro: 4.866 ± 1.446
2.92IleGln: 2.92 ± 0.652
2.92IleArg: 2.92 ± 0.803
6.813IleSer: 6.813 ± 1.048
4.38IleThr: 4.38 ± 0.68
1.946IleVal: 1.946 ± 0.969
1.46IleTrp: 1.46 ± 0.647
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.946LysAla: 1.946 ± 0.562
0.973LysCys: 0.973 ± 0.571
4.38LysAsp: 4.38 ± 2.567
1.46LysGlu: 1.46 ± 0.737
2.433LysPhe: 2.433 ± 0.501
1.946LysGly: 1.946 ± 0.785
0.973LysHis: 0.973 ± 0.648
0.973LysIle: 0.973 ± 0.648
3.893LysLys: 3.893 ± 0.835
1.946LysLeu: 1.946 ± 0.785
0.487LysMet: 0.487 ± 0.565
2.92LysAsn: 2.92 ± 1.106
3.406LysPro: 3.406 ± 0.816
1.46LysGln: 1.46 ± 0.438
1.46LysArg: 1.46 ± 0.737
1.46LysSer: 1.46 ± 0.856
2.92LysThr: 2.92 ± 1.106
0.973LysVal: 0.973 ± 0.417
0.0LysTrp: 0.0 ± 0.0
2.433LysTyr: 2.433 ± 0.951
0.0LysXaa: 0.0 ± 0.0
Leu
8.273LeuAla: 8.273 ± 2.527
1.946LeuCys: 1.946 ± 0.834
4.866LeuAsp: 4.866 ± 1.612
3.406LeuGlu: 3.406 ± 1.545
3.893LeuPhe: 3.893 ± 1.888
7.786LeuGly: 7.786 ± 1.718
5.839LeuHis: 5.839 ± 1.493
6.813LeuIle: 6.813 ± 1.145
4.866LeuLys: 4.866 ± 1.628
17.032LeuLeu: 17.032 ± 3.902
1.46LeuMet: 1.46 ± 0.696
5.353LeuAsn: 5.353 ± 1.33
15.572LeuPro: 15.572 ± 3.985
11.679LeuGln: 11.679 ± 2.055
5.353LeuArg: 5.353 ± 1.355
7.786LeuSer: 7.786 ± 3.072
10.706LeuThr: 10.706 ± 3.209
6.326LeuVal: 6.326 ± 0.941
2.433LeuTrp: 2.433 ± 0.501
6.326LeuTyr: 6.326 ± 2.377
0.0LeuXaa: 0.0 ± 0.0
Met
1.46MetAla: 1.46 ± 0.438
0.487MetCys: 0.487 ± 0.285
0.973MetAsp: 0.973 ± 0.571
1.46MetGlu: 1.46 ± 1.812
0.487MetPhe: 0.487 ± 0.285
1.46MetGly: 1.46 ± 0.438
0.487MetHis: 0.487 ± 0.565
0.0MetIle: 0.0 ± 0.0
0.487MetLys: 0.487 ± 0.565
0.973MetLeu: 0.973 ± 0.417
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.973MetPro: 0.973 ± 0.571
0.973MetGln: 0.973 ± 0.417
0.487MetArg: 0.487 ± 0.764
0.487MetSer: 0.487 ± 0.285
0.487MetThr: 0.487 ± 0.975
0.487MetVal: 0.487 ± 0.764
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.433AsnAla: 2.433 ± 0.741
0.487AsnCys: 0.487 ± 0.285
0.487AsnAsp: 0.487 ± 0.764
0.973AsnGlu: 0.973 ± 0.967
0.973AsnPhe: 0.973 ± 0.417
2.92AsnGly: 2.92 ± 1.139
1.946AsnHis: 1.946 ± 1.142
2.433AsnIle: 2.433 ± 0.951
1.46AsnLys: 1.46 ± 0.438
3.893AsnLeu: 3.893 ± 1.523
0.0AsnMet: 0.0 ± 0.0
1.46AsnAsn: 1.46 ± 0.92
4.38AsnPro: 4.38 ± 0.944
0.973AsnGln: 0.973 ± 1.114
1.46AsnArg: 1.46 ± 0.856
2.433AsnSer: 2.433 ± 0.806
3.406AsnThr: 3.406 ± 1.833
1.946AsnVal: 1.946 ± 0.562
1.46AsnTrp: 1.46 ± 0.884
1.46AsnTyr: 1.46 ± 0.438
0.0AsnXaa: 0.0 ± 0.0
Pro
5.353ProAla: 5.353 ± 1.092
4.866ProCys: 4.866 ± 0.249
1.946ProAsp: 1.946 ± 0.562
4.38ProGlu: 4.38 ± 1.907
3.406ProPhe: 3.406 ± 1.276
6.813ProGly: 6.813 ± 3.787
4.38ProHis: 4.38 ± 0.814
6.813ProIle: 6.813 ± 2.033
3.406ProLys: 3.406 ± 2.725
9.732ProLeu: 9.732 ± 1.972
1.946ProMet: 1.946 ± 0.933
3.406ProAsn: 3.406 ± 1.375
12.165ProPro: 12.165 ± 5.386
4.38ProGln: 4.38 ± 2.058
4.866ProArg: 4.866 ± 1.483
7.786ProSer: 7.786 ± 1.364
6.813ProThr: 6.813 ± 2.439
7.299ProVal: 7.299 ± 1.567
2.433ProTrp: 2.433 ± 0.741
3.406ProTyr: 3.406 ± 0.656
0.0ProXaa: 0.0 ± 0.0
Gln
8.273GlnAla: 8.273 ± 2.543
1.946GlnCys: 1.946 ± 0.969
2.92GlnAsp: 2.92 ± 0.892
3.406GlnGlu: 3.406 ± 0.95
2.433GlnPhe: 2.433 ± 1.044
3.406GlnGly: 3.406 ± 0.816
0.973GlnHis: 0.973 ± 0.648
3.406GlnIle: 3.406 ± 1.228
1.46GlnLys: 1.46 ± 0.438
7.786GlnLeu: 7.786 ± 0.452
0.973GlnMet: 0.973 ± 0.417
2.433GlnAsn: 2.433 ± 1.459
4.866GlnPro: 4.866 ± 1.256
4.38GlnGln: 4.38 ± 2.317
0.973GlnArg: 0.973 ± 0.571
2.92GlnSer: 2.92 ± 1.18
5.839GlnThr: 5.839 ± 0.67
1.46GlnVal: 1.46 ± 0.92
2.433GlnTrp: 2.433 ± 1.427
2.433GlnTyr: 2.433 ± 0.859
0.0GlnXaa: 0.0 ± 0.0
Arg
3.406ArgAla: 3.406 ± 0.78
0.973ArgCys: 0.973 ± 0.417
1.946ArgAsp: 1.946 ± 1.244
1.46ArgGlu: 1.46 ± 0.737
0.487ArgPhe: 0.487 ± 0.285
2.92ArgGly: 2.92 ± 1.251
1.946ArgHis: 1.946 ± 1.142
0.0ArgIle: 0.0 ± 0.0
1.46ArgLys: 1.46 ± 0.647
6.326ArgLeu: 6.326 ± 1.761
0.487ArgMet: 0.487 ± 0.764
0.973ArgAsn: 0.973 ± 0.648
4.38ArgPro: 4.38 ± 2.97
2.92ArgGln: 2.92 ± 1.322
1.946ArgArg: 1.946 ± 0.61
5.353ArgSer: 5.353 ± 1.948
0.973ArgThr: 0.973 ± 0.886
1.946ArgVal: 1.946 ± 0.834
0.973ArgTrp: 0.973 ± 0.571
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.866SerAla: 4.866 ± 1.692
1.946SerCys: 1.946 ± 0.969
2.433SerAsp: 2.433 ± 0.806
1.946SerGlu: 1.946 ± 0.61
2.433SerPhe: 2.433 ± 2.906
2.433SerGly: 2.433 ± 0.886
3.406SerHis: 3.406 ± 0.78
2.433SerIle: 2.433 ± 0.806
2.92SerLys: 2.92 ± 1.712
12.165SerLeu: 12.165 ± 1.207
0.487SerMet: 0.487 ± 0.285
3.406SerAsn: 3.406 ± 1.573
8.273SerPro: 8.273 ± 1.565
6.326SerGln: 6.326 ± 2.232
6.326SerArg: 6.326 ± 1.407
9.246SerSer: 9.246 ± 0.912
3.406SerThr: 3.406 ± 1.049
1.946SerVal: 1.946 ± 0.933
1.946SerTrp: 1.946 ± 0.61
2.92SerTyr: 2.92 ± 1.106
0.0SerXaa: 0.0 ± 0.0
Thr
2.433ThrAla: 2.433 ± 0.923
1.46ThrCys: 1.46 ± 0.884
3.406ThrAsp: 3.406 ± 1.072
1.946ThrGlu: 1.946 ± 0.933
2.92ThrPhe: 2.92 ± 0.59
3.893ThrGly: 3.893 ± 1.016
3.406ThrHis: 3.406 ± 1.375
3.406ThrIle: 3.406 ± 1.375
0.973ThrLys: 0.973 ± 0.967
11.192ThrLeu: 11.192 ± 3.396
0.973ThrMet: 0.973 ± 0.571
3.406ThrAsn: 3.406 ± 1.072
6.813ThrPro: 6.813 ± 2.261
4.38ThrGln: 4.38 ± 1.5
1.946ThrArg: 1.946 ± 0.61
3.893ThrSer: 3.893 ± 2.622
5.839ThrThr: 5.839 ± 2.099
1.946ThrVal: 1.946 ± 0.969
1.46ThrTrp: 1.46 ± 1.059
0.973ThrTyr: 0.973 ± 0.571
0.0ThrXaa: 0.0 ± 0.0
Val
1.946ValAla: 1.946 ± 0.834
1.46ValCys: 1.46 ± 0.647
1.46ValAsp: 1.46 ± 0.884
1.46ValGlu: 1.46 ± 0.951
0.487ValPhe: 0.487 ± 0.285
0.487ValGly: 0.487 ± 0.285
0.0ValHis: 0.0 ± 0.0
2.433ValIle: 2.433 ± 0.886
0.973ValLys: 0.973 ± 0.571
6.813ValLeu: 6.813 ± 5.185
1.46ValMet: 1.46 ± 0.936
0.973ValAsn: 0.973 ± 0.417
4.866ValPro: 4.866 ± 1.672
3.406ValGln: 3.406 ± 1.207
0.973ValArg: 0.973 ± 0.571
5.839ValSer: 5.839 ± 1.689
0.973ValThr: 0.973 ± 0.648
1.946ValVal: 1.946 ± 0.562
1.46ValTrp: 1.46 ± 0.856
0.487ValTyr: 0.487 ± 0.285
0.0ValXaa: 0.0 ± 0.0
Trp
1.946TrpAla: 1.946 ± 0.785
0.0TrpCys: 0.0 ± 0.0
0.973TrpAsp: 0.973 ± 0.571
0.487TrpGlu: 0.487 ± 0.285
0.487TrpPhe: 0.487 ± 0.285
1.46TrpGly: 1.46 ± 0.647
0.487TrpHis: 0.487 ± 0.285
1.46TrpIle: 1.46 ± 0.438
1.946TrpLys: 1.946 ± 0.61
1.946TrpLeu: 1.946 ± 0.834
0.0TrpMet: 0.0 ± 0.0
0.487TrpAsn: 0.487 ± 0.285
0.973TrpPro: 0.973 ± 0.648
1.946TrpGln: 1.946 ± 0.562
1.46TrpArg: 1.46 ± 0.884
0.973TrpSer: 0.973 ± 1.114
2.92TrpThr: 2.92 ± 0.59
0.973TrpVal: 0.973 ± 0.571
0.0TrpTrp: 0.0 ± 0.0
0.487TrpTyr: 0.487 ± 0.285
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.487TyrAla: 0.487 ± 0.285
0.487TyrCys: 0.487 ± 0.285
1.46TyrAsp: 1.46 ± 0.438
0.0TyrGlu: 0.0 ± 0.0
1.46TyrPhe: 1.46 ± 0.856
0.487TyrGly: 0.487 ± 0.285
2.92TyrHis: 2.92 ± 0.59
1.46TyrIle: 1.46 ± 0.856
1.946TyrLys: 1.946 ± 1.296
4.38TyrLeu: 4.38 ± 0.68
0.973TyrMet: 0.973 ± 0.648
0.973TyrAsn: 0.973 ± 0.417
0.973TyrPro: 0.973 ± 0.417
0.973TyrGln: 0.973 ± 0.967
0.973TyrArg: 0.973 ± 0.417
5.353TyrSer: 5.353 ± 0.633
2.433TyrThr: 2.433 ± 1.263
0.487TyrVal: 0.487 ± 0.565
0.487TyrTrp: 0.487 ± 0.285
0.973TyrTyr: 0.973 ± 0.571
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2056 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski