Amino acid dipepetide frequency for Roseivivax marinus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.653AlaAla: 18.653 ± 0.181	1.11AlaCys: 1.11 ± 0.034	7.795AlaAsp: 7.795 ± 0.09	9.203AlaGlu: 9.203 ± 0.109	4.372AlaPhe: 4.372 ± 0.06	11.795AlaGly: 11.795 ± 0.138	2.4AlaHis: 2.4 ± 0.05	5.544AlaIle: 5.544 ± 0.079	2.845AlaLys: 2.845 ± 0.061	14.486AlaLeu: 14.486 ± 0.145	3.643AlaMet: 3.643 ± 0.069	2.403AlaAsn: 2.403 ± 0.043	6.746AlaPro: 6.746 ± 0.1	4.173AlaGln: 4.173 ± 0.07	10.357AlaArg: 10.357 ± 0.117	5.676AlaSer: 5.676 ± 0.066	6.611AlaThr: 6.611 ± 0.079	8.922AlaVal: 8.922 ± 0.097	1.662AlaTrp: 1.662 ± 0.042	2.376AlaTyr: 2.376 ± 0.044	0.0AlaXaa: 0.0 ± 0.0
Cys	1.076CysAla: 1.076 ± 0.031	0.098CysCys: 0.098 ± 0.009	0.575CysAsp: 0.575 ± 0.023	0.448CysGlu: 0.448 ± 0.02	0.29CysPhe: 0.29 ± 0.015	0.866CysGly: 0.866 ± 0.028	0.277CysHis: 0.277 ± 0.016	0.354CysIle: 0.354 ± 0.017	0.141CysLys: 0.141 ± 0.011	0.829CysLeu: 0.829 ± 0.022	0.143CysMet: 0.143 ± 0.011	0.183CysAsn: 0.183 ± 0.012	0.47CysPro: 0.47 ± 0.02	0.197CysGln: 0.197 ± 0.011	0.56CysArg: 0.56 ± 0.018	0.373CysSer: 0.373 ± 0.016	0.422CysThr: 0.422 ± 0.02	0.57CysVal: 0.57 ± 0.022	0.091CysTrp: 0.091 ± 0.007	0.178CysTyr: 0.178 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	8.689AspAla: 8.689 ± 0.085	0.487AspCys: 0.487 ± 0.021	4.344AspAsp: 4.344 ± 0.108	3.987AspGlu: 3.987 ± 0.059	2.254AspPhe: 2.254 ± 0.055	6.645AspGly: 6.645 ± 0.127	1.317AspHis: 1.317 ± 0.038	2.824AspIle: 2.824 ± 0.05	1.285AspLys: 1.285 ± 0.038	6.539AspLeu: 6.539 ± 0.063	1.611AspMet: 1.611 ± 0.036	1.189AspAsn: 1.189 ± 0.035	4.091AspPro: 4.091 ± 0.064	1.595AspGln: 1.595 ± 0.037	5.172AspArg: 5.172 ± 0.079	2.319AspSer: 2.319 ± 0.062	3.719AspThr: 3.719 ± 0.087	4.695AspVal: 4.695 ± 0.073	1.232AspTrp: 1.232 ± 0.031	1.564AspTyr: 1.564 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	9.318GluAla: 9.318 ± 0.102	0.314GluCys: 0.314 ± 0.017	3.944GluAsp: 3.944 ± 0.061	3.839GluGlu: 3.839 ± 0.064	1.662GluPhe: 1.662 ± 0.034	5.579GluGly: 5.579 ± 0.071	1.097GluHis: 1.097 ± 0.033	3.539GluIle: 3.539 ± 0.048	1.759GluLys: 1.759 ± 0.043	5.016GluLeu: 5.016 ± 0.067	1.894GluMet: 1.894 ± 0.038	1.6GluAsn: 1.6 ± 0.034	2.846GluPro: 2.846 ± 0.055	1.756GluGln: 1.756 ± 0.045	4.996GluArg: 4.996 ± 0.08	2.367GluSer: 2.367 ± 0.053	4.46GluThr: 4.46 ± 0.062	4.729GluVal: 4.729 ± 0.06	0.767GluTrp: 0.767 ± 0.024	0.948GluTyr: 0.948 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	4.494PheAla: 4.494 ± 0.069	0.359PheCys: 0.359 ± 0.015	2.892PheAsp: 2.892 ± 0.051	2.327PheGlu: 2.327 ± 0.045	1.309PhePhe: 1.309 ± 0.036	3.629PheGly: 3.629 ± 0.052	0.699PheHis: 0.699 ± 0.025	1.341PheIle: 1.341 ± 0.031	0.655PheLys: 0.655 ± 0.025	3.267PheLeu: 3.267 ± 0.059	0.736PheMet: 0.736 ± 0.027	0.867PheAsn: 0.867 ± 0.025	1.472PhePro: 1.472 ± 0.039	0.863PheGln: 0.863 ± 0.028	2.242PheArg: 2.242 ± 0.039	1.896PheSer: 1.896 ± 0.038	1.968PheThr: 1.968 ± 0.047	2.8PheVal: 2.8 ± 0.048	0.546PheTrp: 0.546 ± 0.022	0.834PheTyr: 0.834 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	11.342GlyAla: 11.342 ± 0.111	0.794GlyCys: 0.794 ± 0.028	5.654GlyAsp: 5.654 ± 0.115	5.022GlyGlu: 5.022 ± 0.063	3.425GlyPhe: 3.425 ± 0.052	8.682GlyGly: 8.682 ± 0.192	1.946GlyHis: 1.946 ± 0.048	4.326GlyIle: 4.326 ± 0.058	2.355GlyLys: 2.355 ± 0.057	9.275GlyLeu: 9.275 ± 0.103	2.494GlyMet: 2.494 ± 0.044	2.141GlyAsn: 2.141 ± 0.068	4.212GlyPro: 4.212 ± 0.066	2.927GlyGln: 2.927 ± 0.056	6.535GlyArg: 6.535 ± 0.084	4.633GlySer: 4.633 ± 0.076	5.619GlyThr: 5.619 ± 0.176	6.522GlyVal: 6.522 ± 0.084	1.505GlyTrp: 1.505 ± 0.034	2.236GlyTyr: 2.236 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	2.465HisAla: 2.465 ± 0.049	0.232HisCys: 0.232 ± 0.013	1.313HisAsp: 1.313 ± 0.039	1.073HisGlu: 1.073 ± 0.03	0.721HisPhe: 0.721 ± 0.023	1.912HisGly: 1.912 ± 0.047	0.537HisHis: 0.537 ± 0.024	0.758HisIle: 0.758 ± 0.021	0.383HisLys: 0.383 ± 0.019	1.999HisLeu: 1.999 ± 0.041	0.463HisMet: 0.463 ± 0.019	0.384HisAsn: 0.384 ± 0.018	1.289HisPro: 1.289 ± 0.036	0.485HisGln: 0.485 ± 0.018	1.404HisArg: 1.404 ± 0.036	0.797HisSer: 0.797 ± 0.027	0.803HisThr: 0.803 ± 0.026	1.66HisVal: 1.66 ± 0.037	0.323HisTrp: 0.323 ± 0.017	0.491HisTyr: 0.491 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.521IleAla: 6.521 ± 0.076	0.465IleCys: 0.465 ± 0.019	3.457IleAsp: 3.457 ± 0.058	3.445IleGlu: 3.445 ± 0.046	1.594IlePhe: 1.594 ± 0.043	4.49IleGly: 4.49 ± 0.059	0.789IleHis: 0.789 ± 0.026	1.549IleIle: 1.549 ± 0.044	0.937IleLys: 0.937 ± 0.029	4.42IleLeu: 4.42 ± 0.066	0.84IleMet: 0.84 ± 0.027	1.034IleAsn: 1.034 ± 0.029	2.04IlePro: 2.04 ± 0.043	0.936IleGln: 0.936 ± 0.026	3.054IleArg: 3.054 ± 0.051	2.457IleSer: 2.457 ± 0.049	2.419IleThr: 2.419 ± 0.049	3.904IleVal: 3.904 ± 0.054	0.604IleTrp: 0.604 ± 0.02	1.047IleTyr: 1.047 ± 0.026	0.0IleXaa: 0.0 ± 0.0
Lys	2.961LysAla: 2.961 ± 0.063	0.149LysCys: 0.149 ± 0.01	1.399LysAsp: 1.399 ± 0.04	1.24LysGlu: 1.24 ± 0.042	0.642LysPhe: 0.642 ± 0.024	2.054LysGly: 2.054 ± 0.053	0.468LysHis: 0.468 ± 0.019	1.169LysIle: 1.169 ± 0.033	0.886LysLys: 0.886 ± 0.037	2.243LysLeu: 2.243 ± 0.039	0.645LysMet: 0.645 ± 0.027	0.591LysAsn: 0.591 ± 0.024	1.341LysPro: 1.341 ± 0.04	0.628LysGln: 0.628 ± 0.024	1.93LysArg: 1.93 ± 0.041	1.359LysSer: 1.359 ± 0.042	1.513LysThr: 1.513 ± 0.041	1.789LysVal: 1.789 ± 0.046	0.292LysTrp: 0.292 ± 0.014	0.451LysTyr: 0.451 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	13.358LeuAla: 13.358 ± 0.135	0.894LeuCys: 0.894 ± 0.026	6.622LeuAsp: 6.622 ± 0.078	5.446LeuGlu: 5.446 ± 0.064	3.476LeuPhe: 3.476 ± 0.055	8.567LeuGly: 8.567 ± 0.093	1.768LeuHis: 1.768 ± 0.035	4.537LeuIle: 4.537 ± 0.07	2.45LeuLys: 2.45 ± 0.049	8.519LeuLeu: 8.519 ± 0.109	2.411LeuMet: 2.411 ± 0.05	2.241LeuAsn: 2.241 ± 0.042	5.472LeuPro: 5.472 ± 0.072	2.416LeuGln: 2.416 ± 0.046	7.243LeuArg: 7.243 ± 0.084	6.645LeuSer: 6.645 ± 0.077	5.876LeuThr: 5.876 ± 0.073	7.177LeuVal: 7.177 ± 0.078	1.314LeuTrp: 1.314 ± 0.034	1.905LeuTyr: 1.905 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	3.193MetAla: 3.193 ± 0.051	0.169MetCys: 0.169 ± 0.011	1.304MetAsp: 1.304 ± 0.034	1.311MetGlu: 1.311 ± 0.031	0.76MetPhe: 0.76 ± 0.028	2.074MetGly: 2.074 ± 0.04	0.432MetHis: 0.432 ± 0.021	1.37MetIle: 1.37 ± 0.034	0.822MetLys: 0.822 ± 0.026	2.375MetLeu: 2.375 ± 0.049	0.679MetMet: 0.679 ± 0.027	0.716MetAsn: 0.716 ± 0.026	1.484MetPro: 1.484 ± 0.031	0.861MetGln: 0.861 ± 0.027	1.894MetArg: 1.894 ± 0.046	1.735MetSer: 1.735 ± 0.037	2.061MetThr: 2.061 ± 0.035	1.675MetVal: 1.675 ± 0.038	0.241MetTrp: 0.241 ± 0.014	0.291MetTyr: 0.291 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.884AsnAla: 2.884 ± 0.056	0.22AsnCys: 0.22 ± 0.013	1.546AsnAsp: 1.546 ± 0.055	1.144AsnGlu: 1.144 ± 0.029	0.821AsnPhe: 0.821 ± 0.027	2.286AsnGly: 2.286 ± 0.063	0.435AsnHis: 0.435 ± 0.018	1.037AsnIle: 1.037 ± 0.03	0.425AsnLys: 0.425 ± 0.017	2.161AsnLeu: 2.161 ± 0.042	0.567AsnMet: 0.567 ± 0.02	0.53AsnAsn: 0.53 ± 0.023	1.521AsnPro: 1.521 ± 0.035	0.591AsnGln: 0.591 ± 0.023	1.583AsnArg: 1.583 ± 0.038	0.985AsnSer: 0.985 ± 0.036	1.192AsnThr: 1.192 ± 0.043	1.817AsnVal: 1.817 ± 0.044	0.332AsnTrp: 0.332 ± 0.016	0.56AsnTyr: 0.56 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	6.22ProAla: 6.22 ± 0.096	0.367ProCys: 0.367 ± 0.016	4.418ProAsp: 4.418 ± 0.053	4.676ProGlu: 4.676 ± 0.069	1.878ProPhe: 1.878 ± 0.037	4.922ProGly: 4.922 ± 0.078	1.036ProHis: 1.036 ± 0.028	1.99ProIle: 1.99 ± 0.036	1.336ProLys: 1.336 ± 0.034	4.545ProLeu: 4.545 ± 0.063	1.203ProMet: 1.203 ± 0.03	1.175ProAsn: 1.175 ± 0.03	2.398ProPro: 2.398 ± 0.052	1.506ProGln: 1.506 ± 0.037	3.215ProArg: 3.215 ± 0.055	2.643ProSer: 2.643 ± 0.045	2.443ProThr: 2.443 ± 0.04	4.445ProVal: 4.445 ± 0.071	0.693ProTrp: 0.693 ± 0.024	1.089ProTyr: 1.089 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	3.607GlnAla: 3.607 ± 0.066	0.169GlnCys: 0.169 ± 0.013	1.662GlnAsp: 1.662 ± 0.037	1.589GlnGlu: 1.589 ± 0.036	0.887GlnPhe: 0.887 ± 0.027	2.396GlnGly: 2.396 ± 0.042	0.48GlnHis: 0.48 ± 0.021	1.573GlnIle: 1.573 ± 0.038	0.834GlnLys: 0.834 ± 0.026	2.394GlnLeu: 2.394 ± 0.043	0.828GlnMet: 0.828 ± 0.025	0.776GlnAsn: 0.776 ± 0.026	1.45GlnPro: 1.45 ± 0.034	0.937GlnGln: 0.937 ± 0.035	2.048GlnArg: 2.048 ± 0.04	1.668GlnSer: 1.668 ± 0.045	1.719GlnThr: 1.719 ± 0.034	2.223GlnVal: 2.223 ± 0.046	0.319GlnTrp: 0.319 ± 0.017	0.491GlnTyr: 0.491 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	9.61ArgAla: 9.61 ± 0.114	0.493ArgCys: 0.493 ± 0.019	4.849ArgAsp: 4.849 ± 0.077	4.333ArgGlu: 4.333 ± 0.064	2.748ArgPhe: 2.748 ± 0.042	5.322ArgGly: 5.322 ± 0.079	1.654ArgHis: 1.654 ± 0.042	3.904ArgIle: 3.904 ± 0.056	1.827ArgLys: 1.827 ± 0.044	7.895ArgLeu: 7.895 ± 0.099	1.974ArgMet: 1.974 ± 0.042	1.627ArgAsn: 1.627 ± 0.036	3.802ArgPro: 3.802 ± 0.063	2.198ArgGln: 2.198 ± 0.042	6.022ArgArg: 6.022 ± 0.1	3.354ArgSer: 3.354 ± 0.061	3.685ArgThr: 3.685 ± 0.05	5.288ArgVal: 5.288 ± 0.067	1.016ArgTrp: 1.016 ± 0.027	1.569ArgTyr: 1.569 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	6.128SerAla: 6.128 ± 0.067	0.393SerCys: 0.393 ± 0.017	3.498SerAsp: 3.498 ± 0.058	3.2SerGlu: 3.2 ± 0.049	2.06SerPhe: 2.06 ± 0.04	5.667SerGly: 5.667 ± 0.093	0.966SerHis: 0.966 ± 0.031	2.243SerIle: 2.243 ± 0.045	1.228SerLys: 1.228 ± 0.037	4.709SerLeu: 4.709 ± 0.065	1.296SerMet: 1.296 ± 0.029	1.257SerAsn: 1.257 ± 0.037	2.451SerPro: 2.451 ± 0.051	1.344SerGln: 1.344 ± 0.032	3.327SerArg: 3.327 ± 0.048	2.534SerSer: 2.534 ± 0.056	2.43SerThr: 2.43 ± 0.053	3.885SerVal: 3.885 ± 0.054	0.642SerTrp: 0.642 ± 0.025	1.196SerTyr: 1.196 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	6.705ThrAla: 6.705 ± 0.085	0.46ThrCys: 0.46 ± 0.017	3.555ThrAsp: 3.555 ± 0.064	3.46ThrGlu: 3.46 ± 0.049	2.158ThrPhe: 2.158 ± 0.042	5.91ThrGly: 5.91 ± 0.098	1.059ThrHis: 1.059 ± 0.028	2.633ThrIle: 2.633 ± 0.056	1.068ThrLys: 1.068 ± 0.03	6.387ThrLeu: 6.387 ± 0.094	1.251ThrMet: 1.251 ± 0.033	1.204ThrAsn: 1.204 ± 0.052	3.395ThrPro: 3.395 ± 0.05	1.501ThrGln: 1.501 ± 0.035	3.807ThrArg: 3.807 ± 0.054	2.749ThrSer: 2.749 ± 0.052	2.889ThrThr: 2.889 ± 0.061	4.678ThrVal: 4.678 ± 0.105	0.755ThrTrp: 0.755 ± 0.023	1.26ThrTyr: 1.26 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	9.548ValAla: 9.548 ± 0.098	0.626ValCys: 0.626 ± 0.022	4.331ValAsp: 4.331 ± 0.069	4.741ValGlu: 4.741 ± 0.058	2.807ValPhe: 2.807 ± 0.05	5.775ValGly: 5.775 ± 0.081	1.353ValHis: 1.353 ± 0.032	3.839ValIle: 3.839 ± 0.05	1.716ValLys: 1.716 ± 0.048	7.544ValLeu: 7.544 ± 0.085	1.976ValMet: 1.976 ± 0.042	1.85ValAsn: 1.85 ± 0.048	3.994ValPro: 3.994 ± 0.059	2.034ValGln: 2.034 ± 0.047	5.01ValArg: 5.01 ± 0.069	4.393ValSer: 4.393 ± 0.068	5.088ValThr: 5.088 ± 0.098	6.061ValVal: 6.061 ± 0.082	1.005ValTrp: 1.005 ± 0.03	1.501ValTyr: 1.501 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.461TrpAla: 1.461 ± 0.035	0.138TrpCys: 0.138 ± 0.009	0.745TrpAsp: 0.745 ± 0.026	0.654TrpGlu: 0.654 ± 0.022	0.534TrpPhe: 0.534 ± 0.018	1.036TrpGly: 1.036 ± 0.031	0.342TrpHis: 0.342 ± 0.016	0.707TrpIle: 0.707 ± 0.023	0.381TrpLys: 0.381 ± 0.018	1.61TrpLeu: 1.61 ± 0.037	0.386TrpMet: 0.386 ± 0.017	0.378TrpAsn: 0.378 ± 0.017	0.732TrpPro: 0.732 ± 0.025	0.525TrpGln: 0.525 ± 0.023	1.194TrpArg: 1.194 ± 0.027	0.846TrpSer: 0.846 ± 0.028	0.908TrpThr: 0.908 ± 0.03	0.865TrpVal: 0.865 ± 0.026	0.228TrpTrp: 0.228 ± 0.014	0.237TrpTyr: 0.237 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.539TyrAla: 2.539 ± 0.042	0.203TyrCys: 0.203 ± 0.012	1.654TyrAsp: 1.654 ± 0.037	1.292TyrGlu: 1.292 ± 0.032	0.801TyrPhe: 0.801 ± 0.025	2.037TyrGly: 2.037 ± 0.043	0.436TyrHis: 0.436 ± 0.018	0.764TyrIle: 0.764 ± 0.024	0.418TyrLys: 0.418 ± 0.017	2.125TyrLeu: 2.125 ± 0.035	0.407TyrMet: 0.407 ± 0.019	0.49TyrAsn: 0.49 ± 0.019	0.991TyrPro: 0.991 ± 0.029	0.576TyrGln: 0.576 ± 0.022	1.577TyrArg: 1.577 ± 0.036	1.025TyrSer: 1.025 ± 0.031	1.059TyrThr: 1.059 ± 0.035	1.487TyrVal: 1.487 ± 0.033	0.342TyrTrp: 0.342 ± 0.017	0.521TyrTyr: 0.521 ± 0.02	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4264 proteins (1352812 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---