Amino acid dipepetide frequency for Human rhinovirus A serotype 89 (strain 41467-Gallo) (HRV-89)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.086AlaAla: 5.086 ± 0.0
2.312AlaCys: 2.312 ± 0.0
1.849AlaAsp: 1.849 ± 0.0
1.849AlaGlu: 1.849 ± 0.0
1.849AlaPhe: 1.849 ± 0.0
2.774AlaGly: 2.774 ± 0.0
0.925AlaHis: 0.925 ± 0.0
2.312AlaIle: 2.312 ± 0.0
2.774AlaLys: 2.774 ± 0.0
2.774AlaLeu: 2.774 ± 0.0
2.774AlaMet: 2.774 ± 0.0
2.312AlaAsn: 2.312 ± 0.0
1.849AlaPro: 1.849 ± 0.0
2.774AlaGln: 2.774 ± 0.0
2.774AlaArg: 2.774 ± 0.0
6.935AlaSer: 6.935 ± 0.0
3.236AlaThr: 3.236 ± 0.0
4.623AlaVal: 4.623 ± 0.0
0.925AlaTrp: 0.925 ± 0.0
3.699AlaTyr: 3.699 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.387CysAla: 1.387 ± 0.0
0.925CysCys: 0.925 ± 0.0
1.387CysAsp: 1.387 ± 0.0
0.462CysGlu: 0.462 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.312CysGly: 2.312 ± 0.0
0.925CysHis: 0.925 ± 0.0
0.462CysIle: 0.462 ± 0.0
0.925CysLys: 0.925 ± 0.0
1.387CysLeu: 1.387 ± 0.0
0.925CysMet: 0.925 ± 0.0
1.849CysAsn: 1.849 ± 0.0
1.387CysPro: 1.387 ± 0.0
1.849CysGln: 1.849 ± 0.0
0.462CysArg: 0.462 ± 0.0
1.387CysSer: 1.387 ± 0.0
1.849CysThr: 1.849 ± 0.0
0.925CysVal: 0.925 ± 0.0
0.462CysTrp: 0.462 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.774AspAla: 2.774 ± 0.0
0.925AspCys: 0.925 ± 0.0
3.699AspAsp: 3.699 ± 0.0
2.312AspGlu: 2.312 ± 0.0
1.387AspPhe: 1.387 ± 0.0
4.623AspGly: 4.623 ± 0.0
0.0AspHis: 0.0 ± 0.0
4.161AspIle: 4.161 ± 0.0
3.699AspLys: 3.699 ± 0.0
7.397AspLeu: 7.397 ± 0.0
1.849AspMet: 1.849 ± 0.0
1.387AspAsn: 1.387 ± 0.0
3.236AspPro: 3.236 ± 0.0
1.387AspGln: 1.387 ± 0.0
1.849AspArg: 1.849 ± 0.0
7.397AspSer: 7.397 ± 0.0
3.236AspThr: 3.236 ± 0.0
3.699AspVal: 3.699 ± 0.0
0.925AspTrp: 0.925 ± 0.0
2.312AspTyr: 2.312 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.699GluAla: 3.699 ± 0.0
1.387GluCys: 1.387 ± 0.0
2.312GluAsp: 2.312 ± 0.0
2.312GluGlu: 2.312 ± 0.0
2.312GluPhe: 2.312 ± 0.0
4.161GluGly: 4.161 ± 0.0
2.312GluHis: 2.312 ± 0.0
3.699GluIle: 3.699 ± 0.0
4.161GluLys: 4.161 ± 0.0
2.312GluLeu: 2.312 ± 0.0
0.925GluMet: 0.925 ± 0.0
1.387GluAsn: 1.387 ± 0.0
2.312GluPro: 2.312 ± 0.0
0.925GluGln: 0.925 ± 0.0
1.387GluArg: 1.387 ± 0.0
1.387GluSer: 1.387 ± 0.0
3.236GluThr: 3.236 ± 0.0
2.774GluVal: 2.774 ± 0.0
0.925GluTrp: 0.925 ± 0.0
1.387GluTyr: 1.387 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
1.849PheCys: 1.849 ± 0.0
2.774PheAsp: 2.774 ± 0.0
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
2.774PheGly: 2.774 ± 0.0
1.849PheHis: 1.849 ± 0.0
3.699PheIle: 3.699 ± 0.0
2.774PheLys: 2.774 ± 0.0
3.699PheLeu: 3.699 ± 0.0
1.387PheMet: 1.387 ± 0.0
1.849PheAsn: 1.849 ± 0.0
2.312PhePro: 2.312 ± 0.0
1.387PheGln: 1.387 ± 0.0
1.849PheArg: 1.849 ± 0.0
5.086PheSer: 5.086 ± 0.0
3.699PheThr: 3.699 ± 0.0
1.849PheVal: 1.849 ± 0.0
0.925PheTrp: 0.925 ± 0.0
1.849PheTyr: 1.849 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.387GlyAla: 1.387 ± 0.0
1.849GlyCys: 1.849 ± 0.0
2.312GlyAsp: 2.312 ± 0.0
5.086GlyGlu: 5.086 ± 0.0
2.774GlyPhe: 2.774 ± 0.0
3.236GlyGly: 3.236 ± 0.0
1.387GlyHis: 1.387 ± 0.0
5.548GlyIle: 5.548 ± 0.0
4.623GlyLys: 4.623 ± 0.0
4.161GlyLeu: 4.161 ± 0.0
0.925GlyMet: 0.925 ± 0.0
4.623GlyAsn: 4.623 ± 0.0
2.312GlyPro: 2.312 ± 0.0
2.312GlyGln: 2.312 ± 0.0
3.236GlyArg: 3.236 ± 0.0
5.548GlySer: 5.548 ± 0.0
4.623GlyThr: 4.623 ± 0.0
4.161GlyVal: 4.161 ± 0.0
0.462GlyTrp: 0.462 ± 0.0
3.236GlyTyr: 3.236 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.925HisAla: 0.925 ± 0.0
0.0HisCys: 0.0 ± 0.0
2.774HisAsp: 2.774 ± 0.0
0.925HisGlu: 0.925 ± 0.0
0.925HisPhe: 0.925 ± 0.0
0.925HisGly: 0.925 ± 0.0
0.462HisHis: 0.462 ± 0.0
2.312HisIle: 2.312 ± 0.0
1.849HisLys: 1.849 ± 0.0
1.849HisLeu: 1.849 ± 0.0
0.462HisMet: 0.462 ± 0.0
1.849HisAsn: 1.849 ± 0.0
1.849HisPro: 1.849 ± 0.0
1.387HisGln: 1.387 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.849HisSer: 1.849 ± 0.0
2.312HisThr: 2.312 ± 0.0
2.774HisVal: 2.774 ± 0.0
0.462HisTrp: 0.462 ± 0.0
0.925HisTyr: 0.925 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.623IleAla: 4.623 ± 0.0
1.849IleCys: 1.849 ± 0.0
4.623IleAsp: 4.623 ± 0.0
4.161IleGlu: 4.161 ± 0.0
2.774IlePhe: 2.774 ± 0.0
4.161IleGly: 4.161 ± 0.0
2.312IleHis: 2.312 ± 0.0
4.623IleIle: 4.623 ± 0.0
6.935IleLys: 6.935 ± 0.0
2.774IleLeu: 2.774 ± 0.0
1.387IleMet: 1.387 ± 0.0
3.236IleAsn: 3.236 ± 0.0
6.01IlePro: 6.01 ± 0.0
2.312IleGln: 2.312 ± 0.0
3.699IleArg: 3.699 ± 0.0
1.387IleSer: 1.387 ± 0.0
5.086IleThr: 5.086 ± 0.0
4.161IleVal: 4.161 ± 0.0
0.0IleTrp: 0.0 ± 0.0
4.161IleTyr: 4.161 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.312LysAla: 2.312 ± 0.0
1.387LysCys: 1.387 ± 0.0
4.623LysAsp: 4.623 ± 0.0
4.161LysGlu: 4.161 ± 0.0
4.623LysPhe: 4.623 ± 0.0
3.236LysGly: 3.236 ± 0.0
2.774LysHis: 2.774 ± 0.0
4.161LysIle: 4.161 ± 0.0
2.774LysLys: 2.774 ± 0.0
5.548LysLeu: 5.548 ± 0.0
0.462LysMet: 0.462 ± 0.0
3.236LysAsn: 3.236 ± 0.0
1.849LysPro: 1.849 ± 0.0
1.849LysGln: 1.849 ± 0.0
1.849LysArg: 1.849 ± 0.0
3.699LysSer: 3.699 ± 0.0
3.236LysThr: 3.236 ± 0.0
2.774LysVal: 2.774 ± 0.0
0.462LysTrp: 0.462 ± 0.0
4.161LysTyr: 4.161 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.01LeuAla: 6.01 ± 0.0
1.387LeuCys: 1.387 ± 0.0
6.01LeuAsp: 6.01 ± 0.0
4.161LeuGlu: 4.161 ± 0.0
3.236LeuPhe: 3.236 ± 0.0
4.623LeuGly: 4.623 ± 0.0
2.312LeuHis: 2.312 ± 0.0
7.397LeuIle: 7.397 ± 0.0
5.548LeuLys: 5.548 ± 0.0
7.397LeuLeu: 7.397 ± 0.0
1.387LeuMet: 1.387 ± 0.0
2.312LeuAsn: 2.312 ± 0.0
6.472LeuPro: 6.472 ± 0.0
4.161LeuGln: 4.161 ± 0.0
4.623LeuArg: 4.623 ± 0.0
5.086LeuSer: 5.086 ± 0.0
4.623LeuThr: 4.623 ± 0.0
3.236LeuVal: 3.236 ± 0.0
0.0LeuTrp: 0.0 ± 0.0
2.312LeuTyr: 2.312 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.312MetAla: 2.312 ± 0.0
0.462MetCys: 0.462 ± 0.0
0.925MetAsp: 0.925 ± 0.0
0.462MetGlu: 0.462 ± 0.0
2.312MetPhe: 2.312 ± 0.0
1.387MetGly: 1.387 ± 0.0
0.0MetHis: 0.0 ± 0.0
2.312MetIle: 2.312 ± 0.0
0.462MetLys: 0.462 ± 0.0
3.699MetLeu: 3.699 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.462MetPro: 0.462 ± 0.0
0.925MetGln: 0.925 ± 0.0
0.0MetArg: 0.0 ± 0.0
0.462MetSer: 0.462 ± 0.0
0.925MetThr: 0.925 ± 0.0
2.774MetVal: 2.774 ± 0.0
0.462MetTrp: 0.462 ± 0.0
0.925MetTyr: 0.925 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.774AsnAla: 2.774 ± 0.0
0.925AsnCys: 0.925 ± 0.0
2.312AsnAsp: 2.312 ± 0.0
1.387AsnGlu: 1.387 ± 0.0
1.849AsnPhe: 1.849 ± 0.0
1.849AsnGly: 1.849 ± 0.0
1.387AsnHis: 1.387 ± 0.0
3.236AsnIle: 3.236 ± 0.0
0.462AsnLys: 0.462 ± 0.0
5.548AsnLeu: 5.548 ± 0.0
1.849AsnMet: 1.849 ± 0.0
2.312AsnAsn: 2.312 ± 0.0
3.236AsnPro: 3.236 ± 0.0
1.387AsnGln: 1.387 ± 0.0
0.462AsnArg: 0.462 ± 0.0
3.699AsnSer: 3.699 ± 0.0
3.236AsnThr: 3.236 ± 0.0
3.236AsnVal: 3.236 ± 0.0
0.925AsnTrp: 0.925 ± 0.0
2.312AsnTyr: 2.312 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.623ProAla: 4.623 ± 0.0
0.925ProCys: 0.925 ± 0.0
4.161ProAsp: 4.161 ± 0.0
3.236ProGlu: 3.236 ± 0.0
1.849ProPhe: 1.849 ± 0.0
5.086ProGly: 5.086 ± 0.0
0.925ProHis: 0.925 ± 0.0
1.849ProIle: 1.849 ± 0.0
2.312ProLys: 2.312 ± 0.0
2.312ProLeu: 2.312 ± 0.0
1.849ProMet: 1.849 ± 0.0
0.925ProAsn: 0.925 ± 0.0
4.161ProPro: 4.161 ± 0.0
1.387ProGln: 1.387 ± 0.0
2.312ProArg: 2.312 ± 0.0
6.472ProSer: 6.472 ± 0.0
4.623ProThr: 4.623 ± 0.0
4.623ProVal: 4.623 ± 0.0
0.925ProTrp: 0.925 ± 0.0
2.312ProTyr: 2.312 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.925GlnAla: 0.925 ± 0.0
0.925GlnCys: 0.925 ± 0.0
1.849GlnAsp: 1.849 ± 0.0
4.161GlnGlu: 4.161 ± 0.0
0.925GlnPhe: 0.925 ± 0.0
4.161GlnGly: 4.161 ± 0.0
0.462GlnHis: 0.462 ± 0.0
2.312GlnIle: 2.312 ± 0.0
0.925GlnLys: 0.925 ± 0.0
3.236GlnLeu: 3.236 ± 0.0
0.462GlnMet: 0.462 ± 0.0
1.849GlnAsn: 1.849 ± 0.0
3.699GlnPro: 3.699 ± 0.0
0.925GlnGln: 0.925 ± 0.0
0.0GlnArg: 0.0 ± 0.0
3.699GlnSer: 3.699 ± 0.0
1.387GlnThr: 1.387 ± 0.0
4.623GlnVal: 4.623 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
0.925GlnTyr: 0.925 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.849ArgAla: 1.849 ± 0.0
0.0ArgCys: 0.0 ± 0.0
2.312ArgAsp: 2.312 ± 0.0
1.387ArgGlu: 1.387 ± 0.0
3.236ArgPhe: 3.236 ± 0.0
1.387ArgGly: 1.387 ± 0.0
1.387ArgHis: 1.387 ± 0.0
1.849ArgIle: 1.849 ± 0.0
2.312ArgLys: 2.312 ± 0.0
2.774ArgLeu: 2.774 ± 0.0
0.925ArgMet: 0.925 ± 0.0
2.774ArgAsn: 2.774 ± 0.0
1.849ArgPro: 1.849 ± 0.0
0.462ArgGln: 0.462 ± 0.0
3.236ArgArg: 3.236 ± 0.0
4.623ArgSer: 4.623 ± 0.0
2.312ArgThr: 2.312 ± 0.0
1.387ArgVal: 1.387 ± 0.0
0.462ArgTrp: 0.462 ± 0.0
0.925ArgTyr: 0.925 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
8.322SerAla: 8.322 ± 0.0
0.925SerCys: 0.925 ± 0.0
5.548SerAsp: 5.548 ± 0.0
2.312SerGlu: 2.312 ± 0.0
1.849SerPhe: 1.849 ± 0.0
6.472SerGly: 6.472 ± 0.0
1.387SerHis: 1.387 ± 0.0
5.548SerIle: 5.548 ± 0.0
5.548SerLys: 5.548 ± 0.0
6.935SerLeu: 6.935 ± 0.0
1.849SerMet: 1.849 ± 0.0
3.699SerAsn: 3.699 ± 0.0
2.774SerPro: 2.774 ± 0.0
2.312SerGln: 2.312 ± 0.0
3.236SerArg: 3.236 ± 0.0
9.246SerSer: 9.246 ± 0.0
5.086SerThr: 5.086 ± 0.0
9.709SerVal: 9.709 ± 0.0
1.387SerTrp: 1.387 ± 0.0
3.699SerTyr: 3.699 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.236ThrAla: 3.236 ± 0.0
0.462ThrCys: 0.462 ± 0.0
2.774ThrAsp: 2.774 ± 0.0
1.849ThrGlu: 1.849 ± 0.0
1.387ThrPhe: 1.387 ± 0.0
2.312ThrGly: 2.312 ± 0.0
2.774ThrHis: 2.774 ± 0.0
5.086ThrIle: 5.086 ± 0.0
3.699ThrLys: 3.699 ± 0.0
7.397ThrLeu: 7.397 ± 0.0
0.0ThrMet: 0.0 ± 0.0
4.623ThrAsn: 4.623 ± 0.0
4.161ThrPro: 4.161 ± 0.0
5.548ThrGln: 5.548 ± 0.0
3.236ThrArg: 3.236 ± 0.0
6.935ThrSer: 6.935 ± 0.0
3.236ThrThr: 3.236 ± 0.0
4.161ThrVal: 4.161 ± 0.0
0.925ThrTrp: 0.925 ± 0.0
1.849ThrTyr: 1.849 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.236ValAla: 3.236 ± 0.0
0.925ValCys: 0.925 ± 0.0
2.774ValAsp: 2.774 ± 0.0
2.774ValGlu: 2.774 ± 0.0
5.086ValPhe: 5.086 ± 0.0
5.548ValGly: 5.548 ± 0.0
1.387ValHis: 1.387 ± 0.0
5.086ValIle: 5.086 ± 0.0
3.699ValLys: 3.699 ± 0.0
7.397ValLeu: 7.397 ± 0.0
0.925ValMet: 0.925 ± 0.0
2.774ValAsn: 2.774 ± 0.0
4.161ValPro: 4.161 ± 0.0
1.849ValGln: 1.849 ± 0.0
1.849ValArg: 1.849 ± 0.0
8.784ValSer: 8.784 ± 0.0
5.086ValThr: 5.086 ± 0.0
5.548ValVal: 5.548 ± 0.0
1.387ValTrp: 1.387 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.462TrpCys: 0.462 ± 0.0
0.462TrpAsp: 0.462 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.462TrpPhe: 0.462 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.462TrpHis: 0.462 ± 0.0
1.387TrpIle: 1.387 ± 0.0
0.925TrpLys: 0.925 ± 0.0
1.849TrpLeu: 1.849 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.462TrpPro: 0.462 ± 0.0
0.925TrpGln: 0.925 ± 0.0
0.462TrpArg: 0.462 ± 0.0
0.925TrpSer: 0.925 ± 0.0
1.387TrpThr: 1.387 ± 0.0
0.462TrpVal: 0.462 ± 0.0
0.925TrpTrp: 0.925 ± 0.0
1.387TrpTyr: 1.387 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.925TyrAla: 0.925 ± 0.0
1.387TyrCys: 1.387 ± 0.0
2.774TyrAsp: 2.774 ± 0.0
2.312TyrGlu: 2.312 ± 0.0
3.236TyrPhe: 3.236 ± 0.0
2.774TyrGly: 2.774 ± 0.0
1.387TyrHis: 1.387 ± 0.0
3.236TyrIle: 3.236 ± 0.0
2.774TyrLys: 2.774 ± 0.0
1.849TyrLeu: 1.849 ± 0.0
0.462TyrMet: 0.462 ± 0.0
1.387TyrAsn: 1.387 ± 0.0
2.312TyrPro: 2.312 ± 0.0
1.387TyrGln: 1.387 ± 0.0
0.925TyrArg: 0.925 ± 0.0
3.236TyrSer: 3.236 ± 0.0
3.236TyrThr: 3.236 ± 0.0
2.774TyrVal: 2.774 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
2.312TyrTyr: 2.312 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2164 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski