Amino acid dipepetide frequency for Aurantiacibacter gangjinensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.512AlaAla: 16.512 ± 0.214	1.069AlaCys: 1.069 ± 0.041	7.978AlaAsp: 7.978 ± 0.108	8.529AlaGlu: 8.529 ± 0.134	4.306AlaPhe: 4.306 ± 0.088	10.353AlaGly: 10.353 ± 0.124	2.127AlaHis: 2.127 ± 0.062	6.883AlaIle: 6.883 ± 0.093	4.014AlaLys: 4.014 ± 0.108	13.086AlaLeu: 13.086 ± 0.185	4.112AlaMet: 4.112 ± 0.073	3.45AlaAsn: 3.45 ± 0.08	5.383AlaPro: 5.383 ± 0.103	4.495AlaGln: 4.495 ± 0.086	8.638AlaArg: 8.638 ± 0.138	6.409AlaSer: 6.409 ± 0.092	5.742AlaThr: 5.742 ± 0.081	7.784AlaVal: 7.784 ± 0.115	1.483AlaTrp: 1.483 ± 0.048	2.513AlaTyr: 2.513 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	1.022CysAla: 1.022 ± 0.038	0.074CysCys: 0.074 ± 0.009	0.623CysAsp: 0.623 ± 0.026	0.541CysGlu: 0.541 ± 0.026	0.284CysPhe: 0.284 ± 0.02	0.846CysGly: 0.846 ± 0.033	0.173CysHis: 0.173 ± 0.015	0.364CysIle: 0.364 ± 0.022	0.171CysLys: 0.171 ± 0.015	0.642CysLeu: 0.642 ± 0.031	0.164CysMet: 0.164 ± 0.014	0.241CysAsn: 0.241 ± 0.021	0.423CysPro: 0.423 ± 0.024	0.207CysGln: 0.207 ± 0.016	0.505CysArg: 0.505 ± 0.024	0.442CysSer: 0.442 ± 0.026	0.377CysThr: 0.377 ± 0.022	0.596CysVal: 0.596 ± 0.029	0.102CysTrp: 0.102 ± 0.012	0.168CysTyr: 0.168 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	8.306AspAla: 8.306 ± 0.116	0.582AspCys: 0.582 ± 0.029	4.442AspAsp: 4.442 ± 0.149	4.557AspGlu: 4.557 ± 0.085	2.565AspPhe: 2.565 ± 0.059	6.535AspGly: 6.535 ± 0.177	1.374AspHis: 1.374 ± 0.047	3.591AspIle: 3.591 ± 0.081	1.704AspLys: 1.704 ± 0.055	5.925AspLeu: 5.925 ± 0.101	1.832AspMet: 1.832 ± 0.049	1.821AspAsn: 1.821 ± 0.056	3.669AspPro: 3.669 ± 0.066	1.7AspGln: 1.7 ± 0.051	4.742AspArg: 4.742 ± 0.081	2.751AspSer: 2.751 ± 0.071	3.326AspThr: 3.326 ± 0.119	4.447AspVal: 4.447 ± 0.079	1.253AspTrp: 1.253 ± 0.04	1.789AspTyr: 1.789 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	8.662GluAla: 8.662 ± 0.159	0.373GluCys: 0.373 ± 0.022	4.217GluAsp: 4.217 ± 0.088	4.481GluGlu: 4.481 ± 0.089	1.926GluPhe: 1.926 ± 0.061	5.429GluGly: 5.429 ± 0.091	1.25GluHis: 1.25 ± 0.04	3.263GluIle: 3.263 ± 0.065	2.306GluLys: 2.306 ± 0.063	5.803GluLeu: 5.803 ± 0.099	1.82GluMet: 1.82 ± 0.055	1.942GluAsn: 1.942 ± 0.052	2.926GluPro: 2.926 ± 0.073	2.523GluGln: 2.523 ± 0.055	5.351GluArg: 5.351 ± 0.097	2.73GluSer: 2.73 ± 0.063	3.678GluThr: 3.678 ± 0.068	4.018GluVal: 4.018 ± 0.071	1.056GluTrp: 1.056 ± 0.036	1.303GluTyr: 1.303 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	5.027PheAla: 5.027 ± 0.087	0.377PheCys: 0.377 ± 0.021	2.954PheAsp: 2.954 ± 0.078	2.27PheGlu: 2.27 ± 0.062	1.374PhePhe: 1.374 ± 0.061	3.561PheGly: 3.561 ± 0.073	0.671PheHis: 0.671 ± 0.03	1.702PheIle: 1.702 ± 0.057	0.793PheLys: 0.793 ± 0.029	3.033PheLeu: 3.033 ± 0.067	0.817PheMet: 0.817 ± 0.04	1.042PheAsn: 1.042 ± 0.042	1.52PhePro: 1.52 ± 0.042	0.911PheGln: 0.911 ± 0.037	2.098PheArg: 2.098 ± 0.059	2.127PheSer: 2.127 ± 0.07	2.289PheThr: 2.289 ± 0.057	2.645PheVal: 2.645 ± 0.058	0.566PheTrp: 0.566 ± 0.03	0.902PheTyr: 0.902 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	8.944GlyAla: 8.944 ± 0.121	0.799GlyCys: 0.799 ± 0.034	5.719GlyAsp: 5.719 ± 0.161	6.373GlyGlu: 6.373 ± 0.097	3.646GlyPhe: 3.646 ± 0.075	7.934GlyGly: 7.934 ± 0.16	1.826GlyHis: 1.826 ± 0.058	4.374GlyIle: 4.374 ± 0.092	3.113GlyLys: 3.113 ± 0.085	8.36GlyLeu: 8.36 ± 0.102	2.502GlyMet: 2.502 ± 0.061	2.473GlyAsn: 2.473 ± 0.077	3.358GlyPro: 3.358 ± 0.063	2.886GlyGln: 2.886 ± 0.055	5.877GlyArg: 5.877 ± 0.095	4.793GlySer: 4.793 ± 0.092	4.716GlyThr: 4.716 ± 0.096	6.072GlyVal: 6.072 ± 0.096	1.598GlyTrp: 1.598 ± 0.05	2.222GlyTyr: 2.222 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	2.2HisAla: 2.2 ± 0.058	0.233HisCys: 0.233 ± 0.018	1.306HisAsp: 1.306 ± 0.041	1.099HisGlu: 1.099 ± 0.043	0.803HisPhe: 0.803 ± 0.027	1.891HisGly: 1.891 ± 0.051	0.52HisHis: 0.52 ± 0.03	0.911HisIle: 0.911 ± 0.04	0.471HisLys: 0.471 ± 0.024	1.769HisLeu: 1.769 ± 0.054	0.462HisMet: 0.462 ± 0.025	0.475HisAsn: 0.475 ± 0.025	1.222HisPro: 1.222 ± 0.044	0.51HisGln: 0.51 ± 0.026	1.44HisArg: 1.44 ± 0.046	0.934HisSer: 0.934 ± 0.032	0.849HisThr: 0.849 ± 0.033	1.307HisVal: 1.307 ± 0.039	0.316HisTrp: 0.316 ± 0.021	0.582HisTyr: 0.582 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	8.005IleAla: 8.005 ± 0.13	0.468IleCys: 0.468 ± 0.025	3.726IleAsp: 3.726 ± 0.084	3.61IleGlu: 3.61 ± 0.071	1.774IlePhe: 1.774 ± 0.05	5.131IleGly: 5.131 ± 0.089	0.907IleHis: 0.907 ± 0.033	2.313IleIle: 2.313 ± 0.059	1.085IleLys: 1.085 ± 0.043	3.841IleLeu: 3.841 ± 0.082	1.028IleMet: 1.028 ± 0.04	1.324IleAsn: 1.324 ± 0.045	2.302IlePro: 2.302 ± 0.057	1.115IleGln: 1.115 ± 0.038	3.093IleArg: 3.093 ± 0.062	2.622IleSer: 2.622 ± 0.072	2.798IleThr: 2.798 ± 0.068	4.013IleVal: 4.013 ± 0.085	0.657IleTrp: 0.657 ± 0.03	1.088IleTyr: 1.088 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	3.593LysAla: 3.593 ± 0.087	0.132LysCys: 0.132 ± 0.012	1.626LysAsp: 1.626 ± 0.057	1.407LysGlu: 1.407 ± 0.056	0.77LysPhe: 0.77 ± 0.038	2.392LysGly: 2.392 ± 0.061	0.593LysHis: 0.593 ± 0.027	1.335LysIle: 1.335 ± 0.045	1.317LysLys: 1.317 ± 0.065	3.048LysLeu: 3.048 ± 0.072	0.744LysMet: 0.744 ± 0.03	0.712LysAsn: 0.712 ± 0.029	1.66LysPro: 1.66 ± 0.06	0.883LysGln: 0.883 ± 0.041	2.382LysArg: 2.382 ± 0.062	1.544LysSer: 1.544 ± 0.053	1.505LysThr: 1.505 ± 0.051	2.048LysVal: 2.048 ± 0.064	0.349LysTrp: 0.349 ± 0.022	0.569LysTyr: 0.569 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	13.497LeuAla: 13.497 ± 0.155	0.726LeuCys: 0.726 ± 0.031	6.409LeuAsp: 6.409 ± 0.082	5.78LeuGlu: 5.78 ± 0.105	3.481LeuPhe: 3.481 ± 0.073	8.068LeuGly: 8.068 ± 0.118	1.66LeuHis: 1.66 ± 0.047	4.471LeuIle: 4.471 ± 0.087	2.527LeuLys: 2.527 ± 0.077	9.263LeuLeu: 9.263 ± 0.148	2.226LeuMet: 2.226 ± 0.069	2.203LeuAsn: 2.203 ± 0.054	5.339LeuPro: 5.339 ± 0.085	2.72LeuGln: 2.72 ± 0.06	6.568LeuArg: 6.568 ± 0.101	5.898LeuSer: 5.898 ± 0.091	5.269LeuThr: 5.269 ± 0.086	7.235LeuVal: 7.235 ± 0.113	1.151LeuTrp: 1.151 ± 0.045	1.997LeuTyr: 1.997 ± 0.055	0.0LeuXaa: 0.0 ± 0.0
Met	3.491MetAla: 3.491 ± 0.069	0.171MetCys: 0.171 ± 0.015	1.454MetAsp: 1.454 ± 0.043	1.392MetGlu: 1.392 ± 0.039	0.728MetPhe: 0.728 ± 0.032	2.082MetGly: 2.082 ± 0.058	0.49MetHis: 0.49 ± 0.026	1.312MetIle: 1.312 ± 0.043	0.904MetLys: 0.904 ± 0.037	2.785MetLeu: 2.785 ± 0.059	0.702MetMet: 0.702 ± 0.032	0.692MetAsn: 0.692 ± 0.029	1.495MetPro: 1.495 ± 0.047	1.006MetGln: 1.006 ± 0.04	2.077MetArg: 2.077 ± 0.059	1.525MetSer: 1.525 ± 0.046	1.659MetThr: 1.659 ± 0.051	1.807MetVal: 1.807 ± 0.047	0.242MetTrp: 0.242 ± 0.019	0.306MetTyr: 0.306 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.235AsnAla: 3.235 ± 0.057	0.251AsnCys: 0.251 ± 0.019	1.655AsnAsp: 1.655 ± 0.098	1.34AsnGlu: 1.34 ± 0.041	1.049AsnPhe: 1.049 ± 0.043	2.501AsnGly: 2.501 ± 0.066	0.501AsnHis: 0.501 ± 0.025	1.386AsnIle: 1.386 ± 0.045	0.589AsnLys: 0.589 ± 0.029	2.523AsnLeu: 2.523 ± 0.054	0.612AsnMet: 0.612 ± 0.03	0.73AsnAsn: 0.73 ± 0.034	1.802AsnPro: 1.802 ± 0.048	0.761AsnGln: 0.761 ± 0.03	1.94AsnArg: 1.94 ± 0.054	1.329AsnSer: 1.329 ± 0.052	1.335AsnThr: 1.335 ± 0.053	1.944AsnVal: 1.944 ± 0.053	0.447AsnTrp: 0.447 ± 0.025	0.675AsnTyr: 0.675 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	5.86ProAla: 5.86 ± 0.117	0.307ProCys: 0.307 ± 0.02	4.142ProAsp: 4.142 ± 0.077	3.917ProGlu: 3.917 ± 0.074	1.919ProPhe: 1.919 ± 0.048	4.082ProGly: 4.082 ± 0.08	0.987ProHis: 0.987 ± 0.039	2.369ProIle: 2.369 ± 0.054	1.344ProLys: 1.344 ± 0.045	4.665ProLeu: 4.665 ± 0.08	1.108ProMet: 1.108 ± 0.039	1.167ProAsn: 1.167 ± 0.037	2.558ProPro: 2.558 ± 0.087	1.887ProGln: 1.887 ± 0.049	2.7ProArg: 2.7 ± 0.067	2.566ProSer: 2.566 ± 0.051	2.454ProThr: 2.454 ± 0.053	4.082ProVal: 4.082 ± 0.064	0.647ProTrp: 0.647 ± 0.032	1.038ProTyr: 1.038 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	3.945GlnAla: 3.945 ± 0.073	0.214GlnCys: 0.214 ± 0.017	1.783GlnAsp: 1.783 ± 0.045	1.692GlnGlu: 1.692 ± 0.05	1.233GlnPhe: 1.233 ± 0.041	2.47GlnGly: 2.47 ± 0.055	0.624GlnHis: 0.624 ± 0.029	1.694GlnIle: 1.694 ± 0.048	0.858GlnLys: 0.858 ± 0.035	3.291GlnLeu: 3.291 ± 0.07	0.962GlnMet: 0.962 ± 0.039	0.797GlnAsn: 0.797 ± 0.035	1.713GlnPro: 1.713 ± 0.058	1.296GlnGln: 1.296 ± 0.052	2.598GlnArg: 2.598 ± 0.073	1.78GlnSer: 1.78 ± 0.054	1.566GlnThr: 1.566 ± 0.043	2.398GlnVal: 2.398 ± 0.056	0.393GlnTrp: 0.393 ± 0.023	0.688GlnTyr: 0.688 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	7.835ArgAla: 7.835 ± 0.138	0.454ArgCys: 0.454 ± 0.028	4.618ArgAsp: 4.618 ± 0.083	4.926ArgGlu: 4.926 ± 0.102	2.995ArgPhe: 2.995 ± 0.065	5.042ArgGly: 5.042 ± 0.095	1.494ArgHis: 1.494 ± 0.044	4.074ArgIle: 4.074 ± 0.069	2.118ArgLys: 2.118 ± 0.059	7.266ArgLeu: 7.266 ± 0.107	2.004ArgMet: 2.004 ± 0.057	1.876ArgAsn: 1.876 ± 0.046	3.088ArgPro: 3.088 ± 0.071	2.438ArgGln: 2.438 ± 0.057	5.08ArgArg: 5.08 ± 0.113	3.594ArgSer: 3.594 ± 0.068	3.169ArgThr: 3.169 ± 0.07	4.519ArgVal: 4.519 ± 0.078	1.11ArgTrp: 1.11 ± 0.044	1.775ArgTyr: 1.775 ± 0.052	0.0ArgXaa: 0.0 ± 0.0
Ser	6.266SerAla: 6.266 ± 0.1	0.42SerCys: 0.42 ± 0.023	3.652SerAsp: 3.652 ± 0.092	3.164SerGlu: 3.164 ± 0.064	2.019SerPhe: 2.019 ± 0.063	5.48SerGly: 5.48 ± 0.084	0.961SerHis: 0.961 ± 0.036	2.594SerIle: 2.594 ± 0.07	1.298SerLys: 1.298 ± 0.048	5.108SerLeu: 5.108 ± 0.09	1.363SerMet: 1.363 ± 0.051	1.41SerAsn: 1.41 ± 0.044	2.612SerPro: 2.612 ± 0.055	1.731SerGln: 1.731 ± 0.047	3.462SerArg: 3.462 ± 0.071	2.612SerSer: 2.612 ± 0.064	2.588SerThr: 2.588 ± 0.061	3.511SerVal: 3.511 ± 0.073	0.806SerTrp: 0.806 ± 0.032	1.298SerTyr: 1.298 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	5.985ThrAla: 5.985 ± 0.091	0.405ThrCys: 0.405 ± 0.027	3.303ThrAsp: 3.303 ± 0.076	2.736ThrGlu: 2.736 ± 0.059	1.945ThrPhe: 1.945 ± 0.055	5.316ThrGly: 5.316 ± 0.092	0.963ThrHis: 0.963 ± 0.037	2.906ThrIle: 2.906 ± 0.077	1.222ThrLys: 1.222 ± 0.04	5.336ThrLeu: 5.336 ± 0.082	1.33ThrMet: 1.33 ± 0.044	1.329ThrAsn: 1.329 ± 0.052	3.237ThrPro: 3.237 ± 0.066	1.476ThrGln: 1.476 ± 0.046	3.365ThrArg: 3.365 ± 0.065	2.684ThrSer: 2.684 ± 0.05	2.552ThrThr: 2.552 ± 0.068	4.221ThrVal: 4.221 ± 0.082	0.577ThrTrp: 0.577 ± 0.027	1.25ThrTyr: 1.25 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	8.575ValAla: 8.575 ± 0.115	0.534ValCys: 0.534 ± 0.028	4.808ValAsp: 4.808 ± 0.077	5.119ValGlu: 5.119 ± 0.086	2.332ValPhe: 2.332 ± 0.057	5.362ValGly: 5.362 ± 0.093	1.32ValHis: 1.32 ± 0.043	3.811ValIle: 3.811 ± 0.076	1.848ValLys: 1.848 ± 0.067	6.888ValLeu: 6.888 ± 0.111	1.772ValMet: 1.772 ± 0.045	1.898ValAsn: 1.898 ± 0.048	3.723ValPro: 3.723 ± 0.077	2.108ValGln: 2.108 ± 0.05	4.472ValArg: 4.472 ± 0.077	3.936ValSer: 3.936 ± 0.074	4.325ValThr: 4.325 ± 0.075	5.255ValVal: 5.255 ± 0.086	0.882ValTrp: 0.882 ± 0.039	1.311ValTyr: 1.311 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	1.289TrpAla: 1.289 ± 0.043	0.115TrpCys: 0.115 ± 0.011	0.836TrpAsp: 0.836 ± 0.036	0.739TrpGlu: 0.739 ± 0.031	0.612TrpPhe: 0.612 ± 0.033	0.947TrpGly: 0.947 ± 0.038	0.372TrpHis: 0.372 ± 0.024	0.66TrpIle: 0.66 ± 0.027	0.402TrpLys: 0.402 ± 0.022	1.812TrpLeu: 1.812 ± 0.064	0.368TrpMet: 0.368 ± 0.021	0.409TrpAsn: 0.409 ± 0.024	0.74TrpPro: 0.74 ± 0.032	0.703TrpGln: 0.703 ± 0.027	1.233TrpArg: 1.233 ± 0.038	0.859TrpSer: 0.859 ± 0.033	0.784TrpThr: 0.784 ± 0.037	0.862TrpVal: 0.862 ± 0.036	0.287TrpTrp: 0.287 ± 0.018	0.28TrpTyr: 0.28 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.618TyrAla: 2.618 ± 0.062	0.256TyrCys: 0.256 ± 0.016	1.661TyrAsp: 1.661 ± 0.052	1.383TyrGlu: 1.383 ± 0.041	0.916TyrPhe: 0.916 ± 0.035	2.165TyrGly: 2.165 ± 0.054	0.489TyrHis: 0.489 ± 0.023	0.887TyrIle: 0.887 ± 0.036	0.525TyrLys: 0.525 ± 0.03	2.042TyrLeu: 2.042 ± 0.056	0.395TyrMet: 0.395 ± 0.022	0.615TyrAsn: 0.615 ± 0.027	1.033TyrPro: 1.033 ± 0.036	0.64TyrGln: 0.64 ± 0.029	1.85TyrArg: 1.85 ± 0.052	1.218TyrSer: 1.218 ± 0.04	1.159TyrThr: 1.159 ± 0.045	1.515TyrVal: 1.515 ± 0.041	0.387TyrTrp: 0.387 ± 0.021	0.604TyrTyr: 0.604 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2492 proteins (788013 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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