Amino acid dipepetide frequency for Moumouvirus goulette

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.177AlaAla: 1.177 ± 0.078
0.901AlaCys: 0.901 ± 0.076
1.883AlaAsp: 1.883 ± 0.107
1.298AlaGlu: 1.298 ± 0.074
1.446AlaPhe: 1.446 ± 0.071
1.456AlaGly: 1.456 ± 0.105
0.582AlaHis: 0.582 ± 0.049
2.883AlaIle: 2.883 ± 0.111
2.14AlaLys: 2.14 ± 0.096
2.748AlaLeu: 2.748 ± 0.142
0.582AlaMet: 0.582 ± 0.044
2.37AlaAsn: 2.37 ± 0.106
0.733AlaPro: 0.733 ± 0.07
0.963AlaGln: 0.963 ± 0.061
0.989AlaArg: 0.989 ± 0.071
2.557AlaSer: 2.557 ± 0.143
1.433AlaThr: 1.433 ± 0.083
1.387AlaVal: 1.387 ± 0.075
0.201AlaTrp: 0.201 ± 0.021
1.338AlaTyr: 1.338 ± 0.069
0.0AlaXaa: 0.0 ± 0.0
Cys
0.707CysAla: 0.707 ± 0.055
0.47CysCys: 0.47 ± 0.046
1.157CysAsp: 1.157 ± 0.082
1.137CysGlu: 1.137 ± 0.067
0.697CysPhe: 0.697 ± 0.051
1.348CysGly: 1.348 ± 0.117
0.523CysHis: 0.523 ± 0.041
1.903CysIle: 1.903 ± 0.147
1.43CysLys: 1.43 ± 0.083
1.525CysLeu: 1.525 ± 0.074
0.352CysMet: 0.352 ± 0.035
1.325CysAsn: 1.325 ± 0.074
0.759CysPro: 0.759 ± 0.077
0.634CysGln: 0.634 ± 0.042
0.671CysArg: 0.671 ± 0.048
1.058CysSer: 1.058 ± 0.072
0.782CysThr: 0.782 ± 0.056
0.963CysVal: 0.963 ± 0.051
0.164CysTrp: 0.164 ± 0.024
0.884CysTyr: 0.884 ± 0.057
0.0CysXaa: 0.0 ± 0.0
Asp
1.505AspAla: 1.505 ± 0.069
0.983AspCys: 0.983 ± 0.057
3.987AspAsp: 3.987 ± 0.155
3.898AspGlu: 3.898 ± 0.119
3.395AspPhe: 3.395 ± 0.113
2.035AspGly: 2.035 ± 0.107
1.078AspHis: 1.078 ± 0.062
7.931AspIle: 7.931 ± 0.207
6.702AspLys: 6.702 ± 0.367
5.667AspLeu: 5.667 ± 0.229
1.239AspMet: 1.239 ± 0.073
5.831AspAsn: 5.831 ± 0.15
2.061AspPro: 2.061 ± 0.093
1.463AspGln: 1.463 ± 0.08
1.371AspArg: 1.371 ± 0.087
3.642AspSer: 3.642 ± 0.117
2.676AspThr: 2.676 ± 0.104
2.945AspVal: 2.945 ± 0.094
0.559AspTrp: 0.559 ± 0.055
3.675AspTyr: 3.675 ± 0.107
0.0AspXaa: 0.0 ± 0.0
Glu
1.482GluAla: 1.482 ± 0.079
1.091GluCys: 1.091 ± 0.067
2.781GluAsp: 2.781 ± 0.123
3.379GluGlu: 3.379 ± 0.154
2.909GluPhe: 2.909 ± 0.103
1.545GluGly: 1.545 ± 0.078
0.881GluHis: 0.881 ± 0.054
6.492GluIle: 6.492 ± 0.158
5.887GluLys: 5.887 ± 0.165
5.029GluLeu: 5.029 ± 0.147
1.233GluMet: 1.233 ± 0.072
6.031GluAsn: 6.031 ± 0.16
1.489GluPro: 1.489 ± 0.138
1.643GluGln: 1.643 ± 0.08
1.683GluArg: 1.683 ± 0.089
3.79GluSer: 3.79 ± 0.151
2.919GluThr: 2.919 ± 0.121
1.979GluVal: 1.979 ± 0.093
0.408GluTrp: 0.408 ± 0.039
3.652GluTyr: 3.652 ± 0.124
0.0GluXaa: 0.0 ± 0.0
Phe
1.367PheAla: 1.367 ± 0.07
0.871PheCys: 0.871 ± 0.059
3.422PheAsp: 3.422 ± 0.124
2.722PheGlu: 2.722 ± 0.115
2.123PhePhe: 2.123 ± 0.092
3.106PheGly: 3.106 ± 0.176
0.815PheHis: 0.815 ± 0.054
4.835PheIle: 4.835 ± 0.137
4.063PheLys: 4.063 ± 0.131
3.629PheLeu: 3.629 ± 0.121
1.144PheMet: 1.144 ± 0.065
5.187PheAsn: 5.187 ± 0.21
1.374PhePro: 1.374 ± 0.07
1.295PheGln: 1.295 ± 0.067
1.361PheArg: 1.361 ± 0.068
3.017PheSer: 3.017 ± 0.108
2.275PheThr: 2.275 ± 0.086
2.041PheVal: 2.041 ± 0.087
0.316PheTrp: 0.316 ± 0.029
2.669PheTyr: 2.669 ± 0.098
0.0PheXaa: 0.0 ± 0.0
Gly
2.298GlyAla: 2.298 ± 0.146
1.203GlyCys: 1.203 ± 0.122
4.063GlyAsp: 4.063 ± 0.747
2.35GlyGlu: 2.35 ± 0.21
2.186GlyPhe: 2.186 ± 0.119
2.692GlyGly: 2.692 ± 0.268
1.311GlyHis: 1.311 ± 0.093
3.957GlyIle: 3.957 ± 0.147
3.415GlyLys: 3.415 ± 0.111
3.402GlyLeu: 3.402 ± 0.153
0.789GlyMet: 0.789 ± 0.093
3.369GlyAsn: 3.369 ± 0.171
1.443GlyPro: 1.443 ± 0.146
1.279GlyGln: 1.279 ± 0.08
1.407GlyArg: 1.407 ± 0.083
3.376GlySer: 3.376 ± 0.315
2.429GlyThr: 2.429 ± 0.162
2.077GlyVal: 2.077 ± 0.096
0.572GlyTrp: 0.572 ± 0.059
2.672GlyTyr: 2.672 ± 0.104
0.0GlyXaa: 0.0 ± 0.0
His
0.743HisAla: 0.743 ± 0.074
0.385HisCys: 0.385 ± 0.038
1.242HisAsp: 1.242 ± 0.073
1.029HisGlu: 1.029 ± 0.058
0.91HisPhe: 0.91 ± 0.054
0.943HisGly: 0.943 ± 0.064
0.68HisHis: 0.68 ± 0.083
2.044HisIle: 2.044 ± 0.095
1.749HisLys: 1.749 ± 0.087
2.429HisLeu: 2.429 ± 0.201
0.414HisMet: 0.414 ± 0.037
1.657HisAsn: 1.657 ± 0.076
0.726HisPro: 0.726 ± 0.056
0.526HisGln: 0.526 ± 0.042
0.575HisArg: 0.575 ± 0.041
1.035HisSer: 1.035 ± 0.064
0.871HisThr: 0.871 ± 0.052
0.841HisVal: 0.841 ± 0.047
0.154HisTrp: 0.154 ± 0.024
1.052HisTyr: 1.052 ± 0.068
0.0HisXaa: 0.0 ± 0.0
Ile
2.465IleAla: 2.465 ± 0.107
1.89IleCys: 1.89 ± 0.095
6.801IleAsp: 6.801 ± 0.19
5.893IleGlu: 5.893 ± 0.202
5.17IlePhe: 5.17 ± 0.148
3.596IleGly: 3.596 ± 0.139
2.281IleHis: 2.281 ± 0.105
12.208IleIle: 12.208 ± 0.301
10.807IleLys: 10.807 ± 0.271
8.727IleLeu: 8.727 ± 0.212
2.09IleMet: 2.09 ± 0.096
11.471IleAsn: 11.471 ± 0.305
4.362IlePro: 4.362 ± 0.208
2.722IleGln: 2.722 ± 0.106
2.886IleArg: 2.886 ± 0.115
6.899IleSer: 6.899 ± 0.186
5.003IleThr: 5.003 ± 0.141
4.631IleVal: 4.631 ± 0.137
0.779IleTrp: 0.779 ± 0.053
5.939IleTyr: 5.939 ± 0.187
0.0IleXaa: 0.0 ± 0.0
Lys
1.837LysAla: 1.837 ± 0.079
1.673LysCys: 1.673 ± 0.078
3.803LysAsp: 3.803 ± 0.131
4.358LysGlu: 4.358 ± 0.181
4.572LysPhe: 4.572 ± 0.177
4.395LysGly: 4.395 ± 0.758
1.561LysHis: 1.561 ± 0.069
11.267LysIle: 11.267 ± 0.264
9.193LysLys: 9.193 ± 0.299
7.8LysLeu: 7.8 ± 0.218
2.018LysMet: 2.018 ± 0.078
10.692LysAsn: 10.692 ± 0.279
2.298LysPro: 2.298 ± 0.105
2.485LysGln: 2.485 ± 0.109
2.182LysArg: 2.182 ± 0.096
5.663LysSer: 5.663 ± 0.197
4.322LysThr: 4.322 ± 0.126
2.643LysVal: 2.643 ± 0.105
0.809LysTrp: 0.809 ± 0.064
8.575LysTyr: 8.575 ± 0.233
0.0LysXaa: 0.0 ± 0.0
Leu
2.712LeuAla: 2.712 ± 0.101
1.223LeuCys: 1.223 ± 0.065
5.696LeuAsp: 5.696 ± 0.156
5.68LeuGlu: 5.68 ± 0.18
3.744LeuPhe: 3.744 ± 0.116
3.701LeuGly: 3.701 ± 0.241
1.41LeuHis: 1.41 ± 0.07
8.096LeuIle: 8.096 ± 0.196
7.514LeuLys: 7.514 ± 0.216
7.773LeuLeu: 7.773 ± 0.253
1.811LeuMet: 1.811 ± 0.111
7.228LeuAsn: 7.228 ± 0.21
2.889LeuPro: 2.889 ± 0.109
2.781LeuGln: 2.781 ± 0.107
2.906LeuArg: 2.906 ± 0.142
6.291LeuSer: 6.291 ± 0.152
4.174LeuThr: 4.174 ± 0.14
4.141LeuVal: 4.141 ± 0.161
0.555LeuTrp: 0.555 ± 0.041
4.076LeuTyr: 4.076 ± 0.112
0.0LeuXaa: 0.0 ± 0.0
Met
0.815MetAla: 0.815 ± 0.052
0.411MetCys: 0.411 ± 0.034
1.43MetAsp: 1.43 ± 0.07
1.305MetGlu: 1.305 ± 0.066
0.871MetPhe: 0.871 ± 0.05
0.91MetGly: 0.91 ± 0.078
0.394MetHis: 0.394 ± 0.04
1.956MetIle: 1.956 ± 0.086
1.545MetLys: 1.545 ± 0.071
1.397MetLeu: 1.397 ± 0.069
0.447MetMet: 0.447 ± 0.044
2.025MetAsn: 2.025 ± 0.141
0.638MetPro: 0.638 ± 0.048
0.48MetGln: 0.48 ± 0.05
0.595MetArg: 0.595 ± 0.045
1.949MetSer: 1.949 ± 0.064
1.259MetThr: 1.259 ± 0.065
0.878MetVal: 0.878 ± 0.06
0.158MetTrp: 0.158 ± 0.022
1.022MetTyr: 1.022 ± 0.053
0.0MetXaa: 0.0 ± 0.0
Asn
2.166AsnAla: 2.166 ± 0.084
1.377AsnCys: 1.377 ± 0.066
5.607AsnAsp: 5.607 ± 0.152
4.802AsnGlu: 4.802 ± 0.153
4.51AsnPhe: 4.51 ± 0.134
4.464AsnGly: 4.464 ± 0.173
1.864AsnHis: 1.864 ± 0.089
12.559AsnIle: 12.559 ± 0.287
9.785AsnLys: 9.785 ± 0.252
7.632AsnLeu: 7.632 ± 0.187
2.373AsnMet: 2.373 ± 0.115
12.507AsnAsn: 12.507 ± 0.474
3.044AsnPro: 3.044 ± 0.122
3.119AsnGln: 3.119 ± 0.185
2.485AsnArg: 2.485 ± 0.118
5.703AsnSer: 5.703 ± 0.184
4.736AsnThr: 4.736 ± 0.171
3.951AsnVal: 3.951 ± 0.126
0.809AsnTrp: 0.809 ± 0.071
5.759AsnTyr: 5.759 ± 0.159
0.0AsnXaa: 0.0 ± 0.0
Pro
0.838ProAla: 0.838 ± 0.063
0.644ProCys: 0.644 ± 0.127
2.268ProAsp: 2.268 ± 0.1
2.084ProGlu: 2.084 ± 0.088
1.433ProPhe: 1.433 ± 0.078
1.453ProGly: 1.453 ± 0.092
0.625ProHis: 0.625 ± 0.047
3.625ProIle: 3.625 ± 0.122
2.827ProLys: 2.827 ± 0.109
2.422ProLeu: 2.422 ± 0.119
0.602ProMet: 0.602 ± 0.06
3.251ProAsn: 3.251 ± 0.144
1.058ProPro: 1.058 ± 0.116
1.022ProGln: 1.022 ± 0.071
0.822ProArg: 0.822 ± 0.057
1.992ProSer: 1.992 ± 0.091
1.712ProThr: 1.712 ± 0.098
1.749ProVal: 1.749 ± 0.152
0.224ProTrp: 0.224 ± 0.029
1.528ProTyr: 1.528 ± 0.073
0.0ProXaa: 0.0 ± 0.0
Gln
0.93GlnAla: 0.93 ± 0.064
0.503GlnCys: 0.503 ± 0.043
1.781GlnAsp: 1.781 ± 0.091
1.729GlnGlu: 1.729 ± 0.085
1.193GlnPhe: 1.193 ± 0.064
1.091GlnGly: 1.091 ± 0.085
0.506GlnHis: 0.506 ± 0.038
2.912GlnIle: 2.912 ± 0.108
2.537GlnLys: 2.537 ± 0.099
2.445GlnLeu: 2.445 ± 0.093
0.71GlnMet: 0.71 ± 0.068
3.152GlnAsn: 3.152 ± 0.143
1.085GlnPro: 1.085 ± 0.109
1.282GlnGln: 1.282 ± 0.166
0.901GlnArg: 0.901 ± 0.074
1.791GlnSer: 1.791 ± 0.099
1.505GlnThr: 1.505 ± 0.085
1.384GlnVal: 1.384 ± 0.074
0.22GlnTrp: 0.22 ± 0.027
1.916GlnTyr: 1.916 ± 0.099
0.0GlnXaa: 0.0 ± 0.0
Arg
0.986ArgAla: 0.986 ± 0.063
0.628ArgCys: 0.628 ± 0.047
1.91ArgAsp: 1.91 ± 0.078
1.854ArgGlu: 1.854 ± 0.092
1.384ArgPhe: 1.384 ± 0.058
1.515ArgGly: 1.515 ± 0.088
0.562ArgHis: 0.562 ± 0.046
2.794ArgIle: 2.794 ± 0.112
2.432ArgLys: 2.432 ± 0.095
2.432ArgLeu: 2.432 ± 0.094
0.559ArgMet: 0.559 ± 0.04
2.748ArgAsn: 2.748 ± 0.121
0.897ArgPro: 0.897 ± 0.066
1.127ArgGln: 1.127 ± 0.072
1.21ArgArg: 1.21 ± 0.079
1.906ArgSer: 1.906 ± 0.159
1.318ArgThr: 1.318 ± 0.072
1.338ArgVal: 1.338 ± 0.083
0.306ArgTrp: 0.306 ± 0.04
1.745ArgTyr: 1.745 ± 0.086
0.0ArgXaa: 0.0 ± 0.0
Ser
1.87SerAla: 1.87 ± 0.121
1.282SerCys: 1.282 ± 0.068
4.625SerAsp: 4.625 ± 0.147
4.194SerGlu: 4.194 ± 0.147
2.794SerPhe: 2.794 ± 0.117
4.227SerGly: 4.227 ± 0.259
1.206SerHis: 1.206 ± 0.072
6.008SerIle: 6.008 ± 0.188
6.202SerLys: 6.202 ± 0.204
5.052SerLeu: 5.052 ± 0.157
1.183SerMet: 1.183 ± 0.067
6.107SerAsn: 6.107 ± 0.207
1.877SerPro: 1.877 ± 0.097
2.235SerGln: 2.235 ± 0.091
2.482SerArg: 2.482 ± 0.149
4.996SerSer: 4.996 ± 0.196
3.349SerThr: 3.349 ± 0.13
3.195SerVal: 3.195 ± 0.148
0.486SerTrp: 0.486 ± 0.041
2.912SerTyr: 2.912 ± 0.094
0.0SerXaa: 0.0 ± 0.0
Thr
1.607ThrAla: 1.607 ± 0.099
0.927ThrCys: 0.927 ± 0.058
2.909ThrAsp: 2.909 ± 0.112
2.531ThrGlu: 2.531 ± 0.104
2.294ThrPhe: 2.294 ± 0.106
2.823ThrGly: 2.823 ± 0.158
1.505ThrHis: 1.505 ± 0.164
4.855ThrIle: 4.855 ± 0.168
4.049ThrLys: 4.049 ± 0.127
3.487ThrLeu: 3.487 ± 0.108
0.818ThrMet: 0.818 ± 0.056
4.763ThrAsn: 4.763 ± 0.153
1.929ThrPro: 1.929 ± 0.109
1.39ThrGln: 1.39 ± 0.086
1.867ThrArg: 1.867 ± 0.077
3.451ThrSer: 3.451 ± 0.145
2.722ThrThr: 2.722 ± 0.16
2.104ThrVal: 2.104 ± 0.1
0.47ThrTrp: 0.47 ± 0.045
2.314ThrTyr: 2.314 ± 0.083
0.0ThrXaa: 0.0 ± 0.0
Val
1.374ValAla: 1.374 ± 0.083
0.809ValCys: 0.809 ± 0.057
2.922ValAsp: 2.922 ± 0.108
2.784ValGlu: 2.784 ± 0.112
1.929ValPhe: 1.929 ± 0.092
1.821ValGly: 1.821 ± 0.087
0.805ValHis: 0.805 ± 0.057
4.046ValIle: 4.046 ± 0.177
4.542ValLys: 4.542 ± 0.18
3.474ValLeu: 3.474 ± 0.115
0.809ValMet: 0.809 ± 0.051
3.856ValAsn: 3.856 ± 0.126
1.584ValPro: 1.584 ± 0.077
1.193ValGln: 1.193 ± 0.06
1.374ValArg: 1.374 ± 0.074
2.873ValSer: 2.873 ± 0.092
2.422ValThr: 2.422 ± 0.149
2.567ValVal: 2.567 ± 0.117
0.348ValTrp: 0.348 ± 0.038
2.288ValTyr: 2.288 ± 0.081
0.0ValXaa: 0.0 ± 0.0
Trp
0.496TrpAla: 0.496 ± 0.054
0.22TrpCys: 0.22 ± 0.03
0.427TrpAsp: 0.427 ± 0.035
0.332TrpGlu: 0.332 ± 0.034
0.408TrpPhe: 0.408 ± 0.038
0.332TrpGly: 0.332 ± 0.039
0.095TrpHis: 0.095 ± 0.019
0.871TrpIle: 0.871 ± 0.057
0.799TrpLys: 0.799 ± 0.057
0.677TrpLeu: 0.677 ± 0.071
0.164TrpMet: 0.164 ± 0.023
0.753TrpAsn: 0.753 ± 0.06
0.135TrpPro: 0.135 ± 0.022
0.158TrpGln: 0.158 ± 0.021
0.27TrpArg: 0.27 ± 0.031
0.592TrpSer: 0.592 ± 0.043
0.431TrpThr: 0.431 ± 0.059
0.348TrpVal: 0.348 ± 0.033
0.388TrpTrp: 0.388 ± 0.095
0.457TrpTyr: 0.457 ± 0.04
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.689TyrAla: 1.689 ± 0.078
0.999TyrCys: 0.999 ± 0.064
3.928TyrAsp: 3.928 ± 0.137
2.942TyrGlu: 2.942 ± 0.103
3.662TyrPhe: 3.662 ± 0.116
2.837TyrGly: 2.837 ± 0.102
1.321TyrHis: 1.321 ± 0.06
5.377TyrIle: 5.377 ± 0.151
4.529TyrLys: 4.529 ± 0.158
6.653TyrLeu: 6.653 ± 0.205
1.144TyrMet: 1.144 ± 0.073
4.93TyrAsn: 4.93 ± 0.147
1.798TyrPro: 1.798 ± 0.083
1.778TyrGln: 1.778 ± 0.083
1.617TyrArg: 1.617 ± 0.07
3.701TyrSer: 3.701 ± 0.127
2.482TyrThr: 2.482 ± 0.098
2.659TyrVal: 2.659 ± 0.104
0.427TyrTrp: 0.427 ± 0.037
3.52TyrTyr: 3.52 ± 0.148
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 970 proteins (304240 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski