Amino acid dipepetide frequency for Ixeridium yellow mottle virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.28AlaAla: 1.28 ± 0.428
0.64AlaCys: 0.64 ± 0.475
1.921AlaAsp: 1.921 ± 0.469
2.241AlaGlu: 2.241 ± 0.836
2.561AlaPhe: 2.561 ± 0.442
4.481AlaGly: 4.481 ± 1.622
1.601AlaHis: 1.601 ± 1.109
2.881AlaIle: 2.881 ± 1.239
5.442AlaLys: 5.442 ± 1.292
8.963AlaLeu: 8.963 ± 1.643
1.601AlaMet: 1.601 ± 0.799
2.241AlaAsn: 2.241 ± 0.336
6.082AlaPro: 6.082 ± 1.138
1.28AlaGln: 1.28 ± 0.386
7.682AlaArg: 7.682 ± 0.909
5.442AlaSer: 5.442 ± 1.243
5.442AlaThr: 5.442 ± 1.103
2.561AlaVal: 2.561 ± 0.573
0.96AlaTrp: 0.96 ± 0.427
1.601AlaTyr: 1.601 ± 0.513
0.0AlaXaa: 0.0 ± 0.0
Cys
0.96CysAla: 0.96 ± 0.427
0.0CysCys: 0.0 ± 0.0
0.64CysAsp: 0.64 ± 0.261
1.28CysGlu: 1.28 ± 0.322
0.64CysPhe: 0.64 ± 0.248
1.601CysGly: 1.601 ± 0.792
0.0CysHis: 0.0 ± 0.0
0.64CysIle: 0.64 ± 0.248
2.241CysLys: 2.241 ± 0.769
0.32CysLeu: 0.32 ± 0.24
0.32CysMet: 0.32 ± 0.298
0.64CysAsn: 0.64 ± 0.799
0.96CysPro: 0.96 ± 0.449
1.28CysGln: 1.28 ± 0.438
0.0CysArg: 0.0 ± 0.0
1.28CysSer: 1.28 ± 0.628
0.0CysThr: 0.0 ± 0.0
1.28CysVal: 1.28 ± 0.497
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.802AspAla: 4.802 ± 0.669
1.28AspCys: 1.28 ± 0.959
4.161AspAsp: 4.161 ± 0.47
2.881AspGlu: 2.881 ± 1.167
0.96AspPhe: 0.96 ± 0.383
2.241AspGly: 2.241 ± 0.594
0.96AspHis: 0.96 ± 0.427
2.241AspIle: 2.241 ± 1.036
0.64AspLys: 0.64 ± 0.248
4.802AspLeu: 4.802 ± 0.549
0.0AspMet: 0.0 ± 0.0
0.32AspAsn: 0.32 ± 0.298
3.841AspPro: 3.841 ± 0.839
2.241AspGln: 2.241 ± 0.631
2.561AspArg: 2.561 ± 0.589
3.841AspSer: 3.841 ± 0.975
1.601AspThr: 1.601 ± 0.465
1.601AspVal: 1.601 ± 0.557
1.601AspTrp: 1.601 ± 0.635
0.32AspTyr: 0.32 ± 0.298
0.0AspXaa: 0.0 ± 0.0
Glu
3.521GluAla: 3.521 ± 0.493
1.601GluCys: 1.601 ± 0.835
3.521GluAsp: 3.521 ± 0.435
4.802GluGlu: 4.802 ± 1.092
3.521GluPhe: 3.521 ± 0.261
3.521GluGly: 3.521 ± 0.733
0.64GluHis: 0.64 ± 0.248
1.28GluIle: 1.28 ± 0.742
5.442GluLys: 5.442 ± 1.21
8.323GluLeu: 8.323 ± 1.779
1.28GluMet: 1.28 ± 0.278
4.161GluAsn: 4.161 ± 0.999
2.241GluPro: 2.241 ± 1.328
1.28GluGln: 1.28 ± 0.521
2.561GluArg: 2.561 ± 0.463
6.722GluSer: 6.722 ± 1.425
4.802GluThr: 4.802 ± 0.543
2.881GluVal: 2.881 ± 0.77
2.241GluTrp: 2.241 ± 0.389
0.96GluTyr: 0.96 ± 0.638
0.0GluXaa: 0.0 ± 0.0
Phe
5.122PheAla: 5.122 ± 1.196
0.32PheCys: 0.32 ± 0.24
1.601PheAsp: 1.601 ± 0.534
1.921PheGlu: 1.921 ± 0.344
1.921PhePhe: 1.921 ± 0.745
3.841PheGly: 3.841 ± 0.955
0.32PheHis: 0.32 ± 0.24
1.921PheIle: 1.921 ± 0.43
3.521PheLys: 3.521 ± 0.876
4.481PheLeu: 4.481 ± 1.398
0.32PheMet: 0.32 ± 0.399
2.241PheAsn: 2.241 ± 0.775
1.921PhePro: 1.921 ± 0.765
1.28PheGln: 1.28 ± 0.76
2.561PheArg: 2.561 ± 0.773
3.841PheSer: 3.841 ± 0.874
1.921PheThr: 1.921 ± 0.587
4.481PheVal: 4.481 ± 0.509
0.32PheTrp: 0.32 ± 0.298
0.64PheTyr: 0.64 ± 0.248
0.0PheXaa: 0.0 ± 0.0
Gly
6.402GlyAla: 6.402 ± 1.517
1.28GlyCys: 1.28 ± 0.278
2.881GlyAsp: 2.881 ± 0.921
6.082GlyGlu: 6.082 ± 0.969
2.881GlyPhe: 2.881 ± 1.483
2.561GlyGly: 2.561 ± 1.494
0.64GlyHis: 0.64 ± 0.47
2.561GlyIle: 2.561 ± 0.616
3.841GlyLys: 3.841 ± 0.915
2.561GlyLeu: 2.561 ± 0.555
0.0GlyMet: 0.0 ± 0.0
4.481GlyAsn: 4.481 ± 0.931
3.201GlyPro: 3.201 ± 0.922
0.96GlyGln: 0.96 ± 0.335
4.802GlyArg: 4.802 ± 1.327
8.643GlySer: 8.643 ± 1.961
1.921GlyThr: 1.921 ± 0.988
4.161GlyVal: 4.161 ± 0.752
2.241GlyTrp: 2.241 ± 0.927
3.201GlyTyr: 3.201 ± 0.412
0.0GlyXaa: 0.0 ± 0.0
His
0.96HisAla: 0.96 ± 0.357
1.601HisCys: 1.601 ± 0.336
1.601HisAsp: 1.601 ± 0.336
1.921HisGlu: 1.921 ± 0.417
0.64HisPhe: 0.64 ± 0.47
0.32HisGly: 0.32 ± 0.24
0.0HisHis: 0.0 ± 0.0
1.601HisIle: 1.601 ± 0.248
0.32HisLys: 0.32 ± 0.24
2.241HisLeu: 2.241 ± 0.496
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.601HisPro: 1.601 ± 0.472
0.32HisGln: 0.32 ± 0.24
1.601HisArg: 1.601 ± 0.849
2.881HisSer: 2.881 ± 1.145
2.561HisThr: 2.561 ± 0.993
0.64HisVal: 0.64 ± 0.248
0.64HisTrp: 0.64 ± 0.248
0.32HisTyr: 0.32 ± 0.399
0.0HisXaa: 0.0 ± 0.0
Ile
1.601IleAla: 1.601 ± 0.513
1.28IleCys: 1.28 ± 0.742
1.28IleAsp: 1.28 ± 0.521
1.921IleGlu: 1.921 ± 0.56
2.561IlePhe: 2.561 ± 0.93
1.601IleGly: 1.601 ± 0.401
0.64IleHis: 0.64 ± 0.799
1.921IleIle: 1.921 ± 0.604
1.601IleLys: 1.601 ± 0.522
5.122IleLeu: 5.122 ± 0.965
0.96IleMet: 0.96 ± 0.413
2.561IleAsn: 2.561 ± 0.713
5.762IlePro: 5.762 ± 1.629
2.241IleGln: 2.241 ± 0.628
3.521IleArg: 3.521 ± 0.747
6.722IleSer: 6.722 ± 1.288
4.161IleThr: 4.161 ± 2.084
1.28IleVal: 1.28 ± 0.533
0.64IleTrp: 0.64 ± 0.799
1.921IleTyr: 1.921 ± 0.431
0.0IleXaa: 0.0 ± 0.0
Lys
4.481LysAla: 4.481 ± 0.902
0.0LysCys: 0.0 ± 0.0
1.28LysAsp: 1.28 ± 0.527
3.521LysGlu: 3.521 ± 1.456
2.881LysPhe: 2.881 ± 0.498
5.762LysGly: 5.762 ± 1.116
2.881LysHis: 2.881 ± 0.776
3.521LysIle: 3.521 ± 0.806
1.28LysLys: 1.28 ± 0.401
3.841LysLeu: 3.841 ± 1.218
0.96LysMet: 0.96 ± 0.506
2.881LysAsn: 2.881 ± 0.511
5.122LysPro: 5.122 ± 0.79
2.241LysGln: 2.241 ± 0.642
1.601LysArg: 1.601 ± 0.465
4.802LysSer: 4.802 ± 0.851
3.201LysThr: 3.201 ± 0.836
1.921LysVal: 1.921 ± 0.458
0.64LysTrp: 0.64 ± 0.362
1.28LysTyr: 1.28 ± 0.278
0.32LysXaa: 0.32 ± 0.298
Leu
4.161LeuAla: 4.161 ± 0.887
1.28LeuCys: 1.28 ± 1.129
4.802LeuAsp: 4.802 ± 1.065
6.402LeuGlu: 6.402 ± 0.887
4.481LeuPhe: 4.481 ± 1.551
4.802LeuGly: 4.802 ± 0.685
2.881LeuHis: 2.881 ± 0.343
5.442LeuIle: 5.442 ± 1.243
2.561LeuLys: 2.561 ± 0.848
7.362LeuLeu: 7.362 ± 1.946
0.64LeuMet: 0.64 ± 0.248
4.161LeuAsn: 4.161 ± 0.634
2.561LeuPro: 2.561 ± 0.386
6.082LeuGln: 6.082 ± 0.954
5.442LeuArg: 5.442 ± 1.568
7.682LeuSer: 7.682 ± 1.55
3.841LeuThr: 3.841 ± 0.622
5.762LeuVal: 5.762 ± 1.768
1.921LeuTrp: 1.921 ± 0.621
4.161LeuTyr: 4.161 ± 0.811
0.0LeuXaa: 0.0 ± 0.0
Met
0.64MetAla: 0.64 ± 0.38
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
2.241MetGlu: 2.241 ± 0.589
0.0MetPhe: 0.0 ± 0.0
0.96MetGly: 0.96 ± 0.494
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.28MetLys: 1.28 ± 0.278
0.96MetLeu: 0.96 ± 0.72
0.0MetMet: 0.0 ± 0.0
1.28MetAsn: 1.28 ± 0.729
0.64MetPro: 0.64 ± 0.362
0.32MetGln: 0.32 ± 0.298
0.96MetArg: 0.96 ± 0.216
0.96MetSer: 0.96 ± 0.638
2.561MetThr: 2.561 ± 0.535
1.28MetVal: 1.28 ± 0.438
0.64MetTrp: 0.64 ± 0.542
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.841AsnAla: 3.841 ± 0.932
0.0AsnCys: 0.0 ± 0.0
2.881AsnAsp: 2.881 ± 0.858
0.64AsnGlu: 0.64 ± 0.362
0.96AsnPhe: 0.96 ± 0.383
5.122AsnGly: 5.122 ± 1.15
0.64AsnHis: 0.64 ± 0.248
2.561AsnIle: 2.561 ± 1.23
3.201AsnLys: 3.201 ± 0.58
2.241AsnLeu: 2.241 ± 0.336
0.0AsnMet: 0.0 ± 0.0
0.64AsnAsn: 0.64 ± 0.38
2.561AsnPro: 2.561 ± 0.821
0.96AsnGln: 0.96 ± 0.413
2.881AsnArg: 2.881 ± 0.667
3.841AsnSer: 3.841 ± 0.939
4.481AsnThr: 4.481 ± 1.36
1.28AsnVal: 1.28 ± 0.335
0.96AsnTrp: 0.96 ± 0.475
1.921AsnTyr: 1.921 ± 0.782
0.0AsnXaa: 0.0 ± 0.0
Pro
3.201ProAla: 3.201 ± 1.834
0.32ProCys: 0.32 ± 0.298
2.561ProAsp: 2.561 ± 0.701
3.201ProGlu: 3.201 ± 0.711
1.921ProPhe: 1.921 ± 0.745
5.122ProGly: 5.122 ± 0.882
1.921ProHis: 1.921 ± 0.417
3.521ProIle: 3.521 ± 0.785
3.841ProLys: 3.841 ± 0.414
3.521ProLeu: 3.521 ± 1.384
0.0ProMet: 0.0 ± 0.456
1.28ProAsn: 1.28 ± 0.724
9.283ProPro: 9.283 ± 4.259
3.521ProGln: 3.521 ± 0.444
2.561ProArg: 2.561 ± 1.011
5.442ProSer: 5.442 ± 0.796
5.442ProThr: 5.442 ± 0.886
2.881ProVal: 2.881 ± 1.022
0.0ProTrp: 0.0 ± 0.0
2.561ProTyr: 2.561 ± 0.682
0.0ProXaa: 0.0 ± 0.0
Gln
4.481GlnAla: 4.481 ± 0.489
0.64GlnCys: 0.64 ± 0.248
0.64GlnAsp: 0.64 ± 0.48
1.601GlnGlu: 1.601 ± 0.628
1.921GlnPhe: 1.921 ± 0.492
1.601GlnGly: 1.601 ± 0.248
1.28GlnHis: 1.28 ± 0.628
0.0GlnIle: 0.0 ± 0.0
1.921GlnLys: 1.921 ± 0.344
2.881GlnLeu: 2.881 ± 0.792
0.96GlnMet: 0.96 ± 0.221
1.921GlnAsn: 1.921 ± 0.478
1.601GlnPro: 1.601 ± 0.962
1.28GlnGln: 1.28 ± 1.033
4.802GlnArg: 4.802 ± 1.983
3.201GlnSer: 3.201 ± 0.781
1.28GlnThr: 1.28 ± 0.609
1.28GlnVal: 1.28 ± 0.536
1.28GlnTrp: 1.28 ± 0.494
0.96GlnTyr: 0.96 ± 0.357
0.0GlnXaa: 0.0 ± 0.0
Arg
3.841ArgAla: 3.841 ± 0.271
0.96ArgCys: 0.96 ± 0.216
1.28ArgAsp: 1.28 ± 0.617
3.841ArgGlu: 3.841 ± 0.39
1.601ArgPhe: 1.601 ± 0.248
3.841ArgGly: 3.841 ± 0.679
0.96ArgHis: 0.96 ± 0.592
5.442ArgIle: 5.442 ± 1.573
1.921ArgLys: 1.921 ± 0.722
4.481ArgLeu: 4.481 ± 1.597
0.96ArgMet: 0.96 ± 0.678
3.201ArgAsn: 3.201 ± 1.161
1.921ArgPro: 1.921 ± 1.223
1.601ArgGln: 1.601 ± 0.513
11.524ArgArg: 11.524 ± 5.235
6.082ArgSer: 6.082 ± 1.144
3.521ArgThr: 3.521 ± 1.767
5.122ArgVal: 5.122 ± 0.799
0.64ArgTrp: 0.64 ± 0.261
1.921ArgTyr: 1.921 ± 0.489
0.0ArgXaa: 0.0 ± 0.0
Ser
4.481SerAla: 4.481 ± 0.87
0.64SerCys: 0.64 ± 0.248
4.481SerAsp: 4.481 ± 0.76
8.003SerGlu: 8.003 ± 0.636
4.481SerPhe: 4.481 ± 0.489
8.003SerGly: 8.003 ± 1.405
1.28SerHis: 1.28 ± 0.494
5.442SerIle: 5.442 ± 1.094
3.841SerLys: 3.841 ± 0.399
9.923SerLeu: 9.923 ± 1.114
1.601SerMet: 1.601 ± 0.49
2.241SerAsn: 2.241 ± 0.439
5.762SerPro: 5.762 ± 1.743
2.561SerGln: 2.561 ± 0.92
4.161SerArg: 4.161 ± 1.231
12.484SerSer: 12.484 ± 1.61
5.122SerThr: 5.122 ± 0.86
7.362SerVal: 7.362 ± 1.417
1.921SerTrp: 1.921 ± 0.464
7.362SerTyr: 7.362 ± 1.444
0.0SerXaa: 0.0 ± 0.0
Thr
6.402ThrAla: 6.402 ± 1.05
1.921ThrCys: 1.921 ± 0.43
3.201ThrAsp: 3.201 ± 1.038
3.521ThrGlu: 3.521 ± 0.756
4.802ThrPhe: 4.802 ± 0.807
3.841ThrGly: 3.841 ± 1.017
1.28ThrHis: 1.28 ± 0.428
2.881ThrIle: 2.881 ± 0.976
2.881ThrLys: 2.881 ± 0.596
3.201ThrLeu: 3.201 ± 0.919
1.28ThrMet: 1.28 ± 0.743
2.241ThrAsn: 2.241 ± 0.44
3.201ThrPro: 3.201 ± 1.235
2.241ThrGln: 2.241 ± 0.836
1.601ThrArg: 1.601 ± 0.507
6.402ThrSer: 6.402 ± 0.862
3.841ThrThr: 3.841 ± 1.504
3.841ThrVal: 3.841 ± 0.744
1.28ThrTrp: 1.28 ± 0.335
0.64ThrTyr: 0.64 ± 0.47
0.0ThrXaa: 0.0 ± 0.0
Val
3.521ValAla: 3.521 ± 0.493
0.0ValCys: 0.0 ± 0.0
1.921ValAsp: 1.921 ± 0.713
2.561ValGlu: 2.561 ± 0.841
1.921ValPhe: 1.921 ± 0.478
2.881ValGly: 2.881 ± 0.627
2.241ValHis: 2.241 ± 0.876
2.881ValIle: 2.881 ± 0.584
4.161ValLys: 4.161 ± 0.922
6.082ValLeu: 6.082 ± 1.762
2.561ValMet: 2.561 ± 0.668
1.921ValAsn: 1.921 ± 0.43
2.881ValPro: 2.881 ± 0.864
2.561ValGln: 2.561 ± 0.499
2.241ValArg: 2.241 ± 0.842
5.762ValSer: 5.762 ± 0.708
2.881ValThr: 2.881 ± 0.355
3.841ValVal: 3.841 ± 1.353
0.32ValTrp: 0.32 ± 0.24
2.561ValTyr: 2.561 ± 0.535
0.0ValXaa: 0.0 ± 0.0
Trp
1.28TrpAla: 1.28 ± 0.428
0.0TrpCys: 0.0 ± 0.0
0.64TrpAsp: 0.64 ± 0.248
1.921TrpGlu: 1.921 ± 0.478
1.601TrpPhe: 1.601 ± 0.357
1.601TrpGly: 1.601 ± 0.729
0.64TrpHis: 0.64 ± 0.404
0.64TrpIle: 0.64 ± 0.248
0.64TrpLys: 0.64 ± 0.48
3.201TrpLeu: 3.201 ± 0.454
0.32TrpMet: 0.32 ± 0.24
1.28TrpAsn: 1.28 ± 0.457
0.32TrpPro: 0.32 ± 0.24
0.0TrpGln: 0.0 ± 0.0
1.28TrpArg: 1.28 ± 0.536
1.28TrpSer: 1.28 ± 1.36
1.28TrpThr: 1.28 ± 0.469
0.96TrpVal: 0.96 ± 0.413
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.921TyrAla: 1.921 ± 0.826
0.32TyrCys: 0.32 ± 0.298
1.601TyrAsp: 1.601 ± 0.401
4.802TyrGlu: 4.802 ± 0.903
2.241TyrPhe: 2.241 ± 0.346
1.601TyrGly: 1.601 ± 0.248
0.96TyrHis: 0.96 ± 0.335
1.921TyrIle: 1.921 ± 0.458
3.841TyrLys: 3.841 ± 0.554
1.921TyrLeu: 1.921 ± 0.604
0.64TyrMet: 0.64 ± 0.596
1.921TyrAsn: 1.921 ± 0.478
0.96TyrPro: 0.96 ± 0.403
1.28TyrGln: 1.28 ± 0.396
0.32TyrArg: 0.32 ± 0.24
3.841TyrSer: 3.841 ± 0.876
0.64TyrThr: 0.64 ± 0.596
0.96TyrVal: 0.96 ± 0.216
0.64TyrTrp: 0.64 ± 0.248
1.601TyrTyr: 1.601 ± 0.638
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.32XaaVal: 0.32 ± 0.298
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3125 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski