Amino acid dipepetide frequency for Xanthomonas virus OP1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
13.523AlaAla: 13.523 ± 1.695
0.808AlaCys: 0.808 ± 0.236
5.586AlaAsp: 5.586 ± 0.652
6.247AlaGlu: 6.247 ± 0.654
2.499AlaPhe: 2.499 ± 0.506
9.04AlaGly: 9.04 ± 0.881
1.47AlaHis: 1.47 ± 0.352
4.924AlaIle: 4.924 ± 0.629
6.247AlaLys: 6.247 ± 0.873
8.673AlaLeu: 8.673 ± 0.741
2.205AlaMet: 2.205 ± 0.545
4.41AlaAsn: 4.41 ± 0.661
3.822AlaPro: 3.822 ± 0.48
5.071AlaGln: 5.071 ± 0.613
5.439AlaArg: 5.439 ± 0.717
6.688AlaSer: 6.688 ± 0.751
4.777AlaThr: 4.777 ± 0.856
6.1AlaVal: 6.1 ± 0.7
1.911AlaTrp: 1.911 ± 0.383
3.601AlaTyr: 3.601 ± 0.492
0.0AlaXaa: 0.0 ± 0.0
Cys
0.955CysAla: 0.955 ± 0.311
0.22CysCys: 0.22 ± 0.137
0.367CysAsp: 0.367 ± 0.192
0.588CysGlu: 0.588 ± 0.236
0.367CysPhe: 0.367 ± 0.135
1.176CysGly: 1.176 ± 0.306
0.514CysHis: 0.514 ± 0.233
0.294CysIle: 0.294 ± 0.169
0.808CysLys: 0.808 ± 0.29
0.588CysLeu: 0.588 ± 0.213
0.147CysMet: 0.147 ± 0.1
0.514CysAsn: 0.514 ± 0.218
0.514CysPro: 0.514 ± 0.216
0.514CysGln: 0.514 ± 0.196
0.514CysArg: 0.514 ± 0.188
0.588CysSer: 0.588 ± 0.189
0.661CysThr: 0.661 ± 0.269
0.588CysVal: 0.588 ± 0.215
0.073CysTrp: 0.073 ± 0.067
0.588CysTyr: 0.588 ± 0.217
0.0CysXaa: 0.0 ± 0.0
Asp
4.998AspAla: 4.998 ± 0.653
0.514AspCys: 0.514 ± 0.228
2.719AspAsp: 2.719 ± 0.419
3.16AspGlu: 3.16 ± 0.406
2.499AspPhe: 2.499 ± 0.469
5.218AspGly: 5.218 ± 0.624
1.323AspHis: 1.323 ± 0.362
3.454AspIle: 3.454 ± 0.446
2.499AspLys: 2.499 ± 0.421
5.586AspLeu: 5.586 ± 0.591
2.205AspMet: 2.205 ± 0.374
2.572AspAsn: 2.572 ± 0.439
2.352AspPro: 2.352 ± 0.434
2.572AspGln: 2.572 ± 0.443
3.528AspArg: 3.528 ± 0.627
3.528AspSer: 3.528 ± 0.496
3.601AspThr: 3.601 ± 0.709
3.969AspVal: 3.969 ± 0.479
0.955AspTrp: 0.955 ± 0.198
1.764AspTyr: 1.764 ± 0.36
0.0AspXaa: 0.0 ± 0.0
Glu
6.615GluAla: 6.615 ± 0.905
0.808GluCys: 0.808 ± 0.273
2.793GluAsp: 2.793 ± 0.459
3.381GluGlu: 3.381 ± 0.644
2.278GluPhe: 2.278 ± 0.566
3.454GluGly: 3.454 ± 0.441
1.102GluHis: 1.102 ± 0.252
3.16GluIle: 3.16 ± 0.44
2.719GluLys: 2.719 ± 0.569
5.659GluLeu: 5.659 ± 0.681
1.249GluMet: 1.249 ± 0.279
1.323GluAsn: 1.323 ± 0.381
0.955GluPro: 0.955 ± 0.27
2.205GluGln: 2.205 ± 0.381
2.646GluArg: 2.646 ± 0.426
3.013GluSer: 3.013 ± 0.512
3.528GluThr: 3.528 ± 0.519
4.557GluVal: 4.557 ± 0.8
1.029GluTrp: 1.029 ± 0.302
2.205GluTyr: 2.205 ± 0.432
0.0GluXaa: 0.0 ± 0.0
Phe
2.572PheAla: 2.572 ± 0.526
0.22PheCys: 0.22 ± 0.14
3.087PheAsp: 3.087 ± 0.467
1.396PheGlu: 1.396 ± 0.308
0.735PhePhe: 0.735 ± 0.262
2.278PheGly: 2.278 ± 0.395
0.661PheHis: 0.661 ± 0.219
1.47PheIle: 1.47 ± 0.266
1.249PheLys: 1.249 ± 0.33
2.352PheLeu: 2.352 ± 0.435
0.588PheMet: 0.588 ± 0.243
1.176PheAsn: 1.176 ± 0.3
0.882PhePro: 0.882 ± 0.23
1.176PheGln: 1.176 ± 0.259
1.543PheArg: 1.543 ± 0.391
1.911PheSer: 1.911 ± 0.41
2.058PheThr: 2.058 ± 0.42
3.087PheVal: 3.087 ± 0.585
0.661PheTrp: 0.661 ± 0.203
0.514PheTyr: 0.514 ± 0.246
0.0PheXaa: 0.0 ± 0.0
Gly
6.541GlyAla: 6.541 ± 0.848
1.029GlyCys: 1.029 ± 0.324
4.189GlyAsp: 4.189 ± 0.499
4.41GlyGlu: 4.41 ± 0.709
2.646GlyPhe: 2.646 ± 0.41
6.1GlyGly: 6.1 ± 0.726
1.396GlyHis: 1.396 ± 0.367
4.41GlyIle: 4.41 ± 0.506
4.998GlyLys: 4.998 ± 0.542
7.57GlyLeu: 7.57 ± 0.82
2.131GlyMet: 2.131 ± 0.408
3.675GlyAsn: 3.675 ± 0.464
2.278GlyPro: 2.278 ± 0.347
3.675GlyGln: 3.675 ± 0.54
4.263GlyArg: 4.263 ± 0.538
6.321GlySer: 6.321 ± 0.762
5.071GlyThr: 5.071 ± 0.742
5.218GlyVal: 5.218 ± 0.608
1.176GlyTrp: 1.176 ± 0.295
3.381GlyTyr: 3.381 ± 0.507
0.0GlyXaa: 0.0 ± 0.0
His
1.47HisAla: 1.47 ± 0.34
0.441HisCys: 0.441 ± 0.21
0.882HisAsp: 0.882 ± 0.321
1.396HisGlu: 1.396 ± 0.384
0.514HisPhe: 0.514 ± 0.197
1.764HisGly: 1.764 ± 0.529
0.514HisHis: 0.514 ± 0.229
1.249HisIle: 1.249 ± 0.292
1.396HisLys: 1.396 ± 0.337
1.764HisLeu: 1.764 ± 0.422
0.367HisMet: 0.367 ± 0.191
0.661HisAsn: 0.661 ± 0.227
0.882HisPro: 0.882 ± 0.243
0.661HisGln: 0.661 ± 0.271
0.955HisArg: 0.955 ± 0.282
1.396HisSer: 1.396 ± 0.369
1.837HisThr: 1.837 ± 0.331
1.029HisVal: 1.029 ± 0.339
0.367HisTrp: 0.367 ± 0.168
0.147HisTyr: 0.147 ± 0.114
0.0HisXaa: 0.0 ± 0.0
Ile
5.292IleAla: 5.292 ± 0.691
0.735IleCys: 0.735 ± 0.27
4.189IleAsp: 4.189 ± 0.464
3.307IleGlu: 3.307 ± 0.465
1.029IlePhe: 1.029 ± 0.248
3.748IleGly: 3.748 ± 0.466
0.661IleHis: 0.661 ± 0.215
1.543IleIle: 1.543 ± 0.366
2.572IleLys: 2.572 ± 0.606
2.866IleLeu: 2.866 ± 0.423
1.47IleMet: 1.47 ± 0.418
2.499IleAsn: 2.499 ± 0.45
2.278IlePro: 2.278 ± 0.462
1.984IleGln: 1.984 ± 0.383
2.499IleArg: 2.499 ± 0.416
3.087IleSer: 3.087 ± 0.545
3.454IleThr: 3.454 ± 0.577
3.675IleVal: 3.675 ± 0.532
0.735IleTrp: 0.735 ± 0.225
1.323IleTyr: 1.323 ± 0.379
0.0IleXaa: 0.0 ± 0.0
Lys
5.659LysAla: 5.659 ± 0.739
0.661LysCys: 0.661 ± 0.296
2.866LysAsp: 2.866 ± 0.436
2.94LysGlu: 2.94 ± 0.551
1.47LysPhe: 1.47 ± 0.366
4.116LysGly: 4.116 ± 0.512
1.396LysHis: 1.396 ± 0.305
3.013LysIle: 3.013 ± 0.512
3.675LysLys: 3.675 ± 0.668
4.63LysLeu: 4.63 ± 0.744
1.911LysMet: 1.911 ± 0.375
1.249LysAsn: 1.249 ± 0.247
2.205LysPro: 2.205 ± 0.409
2.793LysGln: 2.793 ± 0.558
3.013LysArg: 3.013 ± 0.542
3.013LysSer: 3.013 ± 0.787
2.646LysThr: 2.646 ± 0.374
3.969LysVal: 3.969 ± 0.585
1.102LysTrp: 1.102 ± 0.274
1.029LysTyr: 1.029 ± 0.266
0.0LysXaa: 0.0 ± 0.0
Leu
9.187LeuAla: 9.187 ± 0.798
0.735LeuCys: 0.735 ± 0.291
5.218LeuAsp: 5.218 ± 0.843
5.145LeuGlu: 5.145 ± 0.649
2.278LeuPhe: 2.278 ± 0.348
6.688LeuGly: 6.688 ± 0.735
2.058LeuHis: 2.058 ± 0.419
3.748LeuIle: 3.748 ± 0.57
3.748LeuLys: 3.748 ± 0.717
7.203LeuLeu: 7.203 ± 0.951
1.543LeuMet: 1.543 ± 0.397
3.528LeuAsn: 3.528 ± 0.369
3.528LeuPro: 3.528 ± 0.642
4.116LeuGln: 4.116 ± 0.718
5.88LeuArg: 5.88 ± 0.548
6.909LeuSer: 6.909 ± 0.76
5.439LeuThr: 5.439 ± 0.607
4.63LeuVal: 4.63 ± 0.511
1.102LeuTrp: 1.102 ± 0.312
2.646LeuTyr: 2.646 ± 0.41
0.0LeuXaa: 0.0 ± 0.0
Met
1.911MetAla: 1.911 ± 0.305
0.073MetCys: 0.073 ± 0.08
1.176MetAsp: 1.176 ± 0.339
1.249MetGlu: 1.249 ± 0.369
0.661MetPhe: 0.661 ± 0.277
1.176MetGly: 1.176 ± 0.296
0.367MetHis: 0.367 ± 0.179
0.955MetIle: 0.955 ± 0.341
0.882MetLys: 0.882 ± 0.3
2.278MetLeu: 2.278 ± 0.372
1.102MetMet: 1.102 ± 0.377
1.102MetAsn: 1.102 ± 0.309
1.396MetPro: 1.396 ± 0.331
1.249MetGln: 1.249 ± 0.302
1.47MetArg: 1.47 ± 0.295
2.572MetSer: 2.572 ± 0.387
2.793MetThr: 2.793 ± 0.512
1.176MetVal: 1.176 ± 0.345
0.367MetTrp: 0.367 ± 0.14
1.176MetTyr: 1.176 ± 0.42
0.0MetXaa: 0.0 ± 0.0
Asn
3.528AsnAla: 3.528 ± 0.475
0.514AsnCys: 0.514 ± 0.201
2.94AsnAsp: 2.94 ± 0.44
1.69AsnGlu: 1.69 ± 0.377
1.176AsnPhe: 1.176 ± 0.267
3.307AsnGly: 3.307 ± 0.482
0.514AsnHis: 0.514 ± 0.208
2.058AsnIle: 2.058 ± 0.286
2.352AsnLys: 2.352 ± 0.389
2.94AsnLeu: 2.94 ± 0.462
0.882AsnMet: 0.882 ± 0.246
2.131AsnAsn: 2.131 ± 0.404
2.205AsnPro: 2.205 ± 0.451
1.911AsnGln: 1.911 ± 0.301
2.205AsnArg: 2.205 ± 0.488
2.205AsnSer: 2.205 ± 0.336
2.719AsnThr: 2.719 ± 0.355
2.425AsnVal: 2.425 ± 0.53
0.514AsnTrp: 0.514 ± 0.211
1.249AsnTyr: 1.249 ± 0.371
0.0AsnXaa: 0.0 ± 0.0
Pro
3.895ProAla: 3.895 ± 0.533
0.073ProCys: 0.073 ± 0.078
3.601ProAsp: 3.601 ± 0.441
2.94ProGlu: 2.94 ± 0.667
1.396ProPhe: 1.396 ± 0.362
4.189ProGly: 4.189 ± 0.602
0.588ProHis: 0.588 ± 0.201
1.176ProIle: 1.176 ± 0.242
2.425ProLys: 2.425 ± 0.483
2.793ProLeu: 2.793 ± 0.531
0.735ProMet: 0.735 ± 0.237
1.47ProAsn: 1.47 ± 0.258
2.131ProPro: 2.131 ± 0.499
1.249ProGln: 1.249 ± 0.265
1.176ProArg: 1.176 ± 0.332
2.205ProSer: 2.205 ± 0.361
2.205ProThr: 2.205 ± 0.438
2.719ProVal: 2.719 ± 0.409
0.367ProTrp: 0.367 ± 0.131
1.102ProTyr: 1.102 ± 0.341
0.0ProXaa: 0.0 ± 0.0
Gln
6.1GlnAla: 6.1 ± 0.702
0.367GlnCys: 0.367 ± 0.182
2.131GlnAsp: 2.131 ± 0.358
2.131GlnGlu: 2.131 ± 0.387
1.47GlnPhe: 1.47 ± 0.312
3.013GlnGly: 3.013 ± 0.519
0.955GlnHis: 0.955 ± 0.307
3.307GlnIle: 3.307 ± 0.497
1.47GlnLys: 1.47 ± 0.416
4.483GlnLeu: 4.483 ± 0.512
1.176GlnMet: 1.176 ± 0.338
1.249GlnAsn: 1.249 ± 0.336
1.249GlnPro: 1.249 ± 0.335
3.013GlnGln: 3.013 ± 0.41
2.719GlnArg: 2.719 ± 0.41
2.793GlnSer: 2.793 ± 0.629
3.307GlnThr: 3.307 ± 0.541
4.263GlnVal: 4.263 ± 0.813
0.808GlnTrp: 0.808 ± 0.209
1.543GlnTyr: 1.543 ± 0.292
0.0GlnXaa: 0.0 ± 0.0
Arg
4.777ArgAla: 4.777 ± 0.497
0.735ArgCys: 0.735 ± 0.286
2.793ArgAsp: 2.793 ± 0.384
3.16ArgGlu: 3.16 ± 0.518
1.617ArgPhe: 1.617 ± 0.452
3.307ArgGly: 3.307 ± 0.426
0.808ArgHis: 0.808 ± 0.308
3.528ArgIle: 3.528 ± 0.475
3.454ArgLys: 3.454 ± 0.638
5.071ArgLeu: 5.071 ± 0.623
1.176ArgMet: 1.176 ± 0.296
1.764ArgAsn: 1.764 ± 0.309
1.911ArgPro: 1.911 ± 0.413
2.94ArgGln: 2.94 ± 0.571
2.866ArgArg: 2.866 ± 0.541
3.601ArgSer: 3.601 ± 0.432
2.572ArgThr: 2.572 ± 0.331
4.483ArgVal: 4.483 ± 0.965
0.514ArgTrp: 0.514 ± 0.194
2.131ArgTyr: 2.131 ± 0.357
0.0ArgXaa: 0.0 ± 0.0
Ser
8.379SerAla: 8.379 ± 1.12
0.294SerCys: 0.294 ± 0.163
3.675SerAsp: 3.675 ± 0.389
3.307SerGlu: 3.307 ± 0.439
1.102SerPhe: 1.102 ± 0.248
6.615SerGly: 6.615 ± 0.854
1.249SerHis: 1.249 ± 0.361
3.381SerIle: 3.381 ± 0.48
3.895SerLys: 3.895 ± 0.535
5.218SerLeu: 5.218 ± 0.554
1.837SerMet: 1.837 ± 0.391
2.94SerAsn: 2.94 ± 0.497
2.058SerPro: 2.058 ± 0.347
2.793SerGln: 2.793 ± 0.423
2.94SerArg: 2.94 ± 0.429
5.071SerSer: 5.071 ± 0.662
3.969SerThr: 3.969 ± 0.616
5.806SerVal: 5.806 ± 0.744
1.249SerTrp: 1.249 ± 0.279
2.058SerTyr: 2.058 ± 0.345
0.0SerXaa: 0.0 ± 0.0
Thr
6.982ThrAla: 6.982 ± 1.105
0.661ThrCys: 0.661 ± 0.206
3.013ThrAsp: 3.013 ± 0.747
1.764ThrGlu: 1.764 ± 0.368
1.984ThrPhe: 1.984 ± 0.486
7.056ThrGly: 7.056 ± 0.869
0.955ThrHis: 0.955 ± 0.256
2.866ThrIle: 2.866 ± 0.501
3.307ThrLys: 3.307 ± 0.482
5.733ThrLeu: 5.733 ± 0.808
1.984ThrMet: 1.984 ± 0.412
1.911ThrAsn: 1.911 ± 0.351
2.719ThrPro: 2.719 ± 0.59
2.719ThrGln: 2.719 ± 0.365
2.866ThrArg: 2.866 ± 0.343
4.042ThrSer: 4.042 ± 0.861
4.483ThrThr: 4.483 ± 0.552
5.071ThrVal: 5.071 ± 0.805
1.102ThrTrp: 1.102 ± 0.309
1.837ThrTyr: 1.837 ± 0.349
0.0ThrXaa: 0.0 ± 0.0
Val
6.762ValAla: 6.762 ± 0.776
0.808ValCys: 0.808 ± 0.318
4.336ValAsp: 4.336 ± 0.692
4.557ValGlu: 4.557 ± 0.735
2.131ValPhe: 2.131 ± 0.317
4.704ValGly: 4.704 ± 0.679
1.911ValHis: 1.911 ± 0.428
2.278ValIle: 2.278 ± 0.482
3.454ValLys: 3.454 ± 0.436
5.512ValLeu: 5.512 ± 0.632
1.102ValMet: 1.102 ± 0.299
3.381ValAsn: 3.381 ± 0.594
3.013ValPro: 3.013 ± 0.484
4.483ValGln: 4.483 ± 0.545
3.307ValArg: 3.307 ± 0.689
4.998ValSer: 4.998 ± 0.666
5.145ValThr: 5.145 ± 0.82
6.1ValVal: 6.1 ± 0.803
1.029ValTrp: 1.029 ± 0.216
2.572ValTyr: 2.572 ± 0.623
0.0ValXaa: 0.0 ± 0.0
Trp
1.176TrpAla: 1.176 ± 0.262
0.441TrpCys: 0.441 ± 0.2
1.029TrpAsp: 1.029 ± 0.25
0.882TrpGlu: 0.882 ± 0.252
0.367TrpPhe: 0.367 ± 0.145
0.735TrpGly: 0.735 ± 0.221
0.661TrpHis: 0.661 ± 0.225
0.588TrpIle: 0.588 ± 0.25
0.808TrpLys: 0.808 ± 0.23
1.617TrpLeu: 1.617 ± 0.377
0.514TrpMet: 0.514 ± 0.252
0.661TrpAsn: 0.661 ± 0.188
0.735TrpPro: 0.735 ± 0.289
1.102TrpGln: 1.102 ± 0.273
1.617TrpArg: 1.617 ± 0.272
0.735TrpSer: 0.735 ± 0.19
0.735TrpThr: 0.735 ± 0.28
0.441TrpVal: 0.441 ± 0.167
0.073TrpTrp: 0.073 ± 0.081
0.661TrpTyr: 0.661 ± 0.185
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.719TyrAla: 2.719 ± 0.466
0.441TyrCys: 0.441 ± 0.212
2.425TyrAsp: 2.425 ± 0.387
1.029TyrGlu: 1.029 ± 0.254
1.396TyrPhe: 1.396 ± 0.307
2.793TyrGly: 2.793 ± 0.491
0.588TyrHis: 0.588 ± 0.221
1.543TyrIle: 1.543 ± 0.368
1.396TyrLys: 1.396 ± 0.267
2.866TyrLeu: 2.866 ± 0.383
0.735TyrMet: 0.735 ± 0.249
1.249TyrAsn: 1.249 ± 0.3
1.323TyrPro: 1.323 ± 0.279
1.323TyrGln: 1.323 ± 0.306
1.764TyrArg: 1.764 ± 0.317
3.16TyrSer: 3.16 ± 0.412
2.058TyrThr: 2.058 ± 0.384
2.278TyrVal: 2.278 ± 0.421
0.441TyrTrp: 0.441 ± 0.176
1.837TyrTyr: 1.837 ± 0.351
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 59 proteins (13607 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski