Amino acid dipepetide frequency for Gordonia sihwensis NBRC 108236

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.419AlaAla: 20.419 ± 0.203	0.927AlaCys: 0.927 ± 0.028	9.412AlaAsp: 9.412 ± 0.106	8.11AlaGlu: 8.11 ± 0.098	3.372AlaPhe: 3.372 ± 0.055	12.128AlaGly: 12.128 ± 0.099	2.573AlaHis: 2.573 ± 0.044	5.064AlaIle: 5.064 ± 0.076	2.93AlaLys: 2.93 ± 0.066	12.57AlaLeu: 12.57 ± 0.141	2.888AlaMet: 2.888 ± 0.05	2.229AlaAsn: 2.229 ± 0.04	6.263AlaPro: 6.263 ± 0.084	3.892AlaGln: 3.892 ± 0.062	9.076AlaArg: 9.076 ± 0.096	6.302AlaSer: 6.302 ± 0.072	7.099AlaThr: 7.099 ± 0.084	12.297AlaVal: 12.297 ± 0.121	1.569AlaTrp: 1.569 ± 0.035	2.305AlaTyr: 2.305 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.924CysAla: 0.924 ± 0.031	0.073CysCys: 0.073 ± 0.009	0.476CysAsp: 0.476 ± 0.022	0.409CysGlu: 0.409 ± 0.018	0.211CysPhe: 0.211 ± 0.013	0.874CysGly: 0.874 ± 0.031	0.157CysHis: 0.157 ± 0.011	0.235CysIle: 0.235 ± 0.015	0.114CysLys: 0.114 ± 0.01	0.58CysLeu: 0.58 ± 0.024	0.124CysMet: 0.124 ± 0.011	0.158CysAsn: 0.158 ± 0.012	0.437CysPro: 0.437 ± 0.022	0.161CysGln: 0.161 ± 0.012	0.552CysArg: 0.552 ± 0.025	0.483CysSer: 0.483 ± 0.021	0.436CysThr: 0.436 ± 0.016	0.595CysVal: 0.595 ± 0.023	0.123CysTrp: 0.123 ± 0.011	0.151CysTyr: 0.151 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	8.427AspAla: 8.427 ± 0.098	0.411AspCys: 0.411 ± 0.02	4.951AspAsp: 4.951 ± 0.071	4.476AspGlu: 4.476 ± 0.065	1.817AspPhe: 1.817 ± 0.041	6.436AspGly: 6.436 ± 0.068	1.472AspHis: 1.472 ± 0.036	2.284AspIle: 2.284 ± 0.045	1.256AspLys: 1.256 ± 0.036	6.669AspLeu: 6.669 ± 0.116	1.02AspMet: 1.02 ± 0.03	1.112AspAsn: 1.112 ± 0.032	4.587AspPro: 4.587 ± 0.061	1.752AspGln: 1.752 ± 0.043	5.447AspArg: 5.447 ± 0.082	3.175AspSer: 3.175 ± 0.056	3.096AspThr: 3.096 ± 0.047	5.571AspVal: 5.571 ± 0.085	0.977AspTrp: 0.977 ± 0.029	1.426AspTyr: 1.426 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	6.387GluAla: 6.387 ± 0.08	0.368GluCys: 0.368 ± 0.02	2.438GluAsp: 2.438 ± 0.051	2.559GluGlu: 2.559 ± 0.056	1.9GluPhe: 1.9 ± 0.042	3.427GluGly: 3.427 ± 0.057	1.447GluHis: 1.447 ± 0.03	2.792GluIle: 2.792 ± 0.04	1.494GluLys: 1.494 ± 0.059	6.533GluLeu: 6.533 ± 0.088	1.147GluMet: 1.147 ± 0.034	1.265GluAsn: 1.265 ± 0.031	3.083GluPro: 3.083 ± 0.06	2.172GluGln: 2.172 ± 0.044	4.737GluArg: 4.737 ± 0.081	3.199GluSer: 3.199 ± 0.061	3.092GluThr: 3.092 ± 0.055	4.695GluVal: 4.695 ± 0.076	0.805GluTrp: 0.805 ± 0.03	1.248GluTyr: 1.248 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.999PheAla: 3.999 ± 0.064	0.292PheCys: 0.292 ± 0.016	2.36PheAsp: 2.36 ± 0.057	1.502PheGlu: 1.502 ± 0.041	0.909PhePhe: 0.909 ± 0.032	3.449PheGly: 3.449 ± 0.059	0.585PheHis: 0.585 ± 0.022	1.041PheIle: 1.041 ± 0.03	0.5PheLys: 0.5 ± 0.02	2.426PheLeu: 2.426 ± 0.052	0.442PheMet: 0.442 ± 0.019	0.653PheAsn: 0.653 ± 0.026	1.287PhePro: 1.287 ± 0.033	0.642PheGln: 0.642 ± 0.024	1.621PheArg: 1.621 ± 0.038	1.669PheSer: 1.669 ± 0.039	2.0PheThr: 2.0 ± 0.034	2.504PheVal: 2.504 ± 0.047	0.411PheTrp: 0.411 ± 0.019	0.632PheTyr: 0.632 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	10.417GlyAla: 10.417 ± 0.103	0.714GlyCys: 0.714 ± 0.029	5.631GlyAsp: 5.631 ± 0.067	4.792GlyGlu: 4.792 ± 0.072	3.043GlyPhe: 3.043 ± 0.051	7.862GlyGly: 7.862 ± 0.106	1.934GlyHis: 1.934 ± 0.039	3.918GlyIle: 3.918 ± 0.075	2.305GlyLys: 2.305 ± 0.053	8.535GlyLeu: 8.535 ± 0.093	2.103GlyMet: 2.103 ± 0.042	1.643GlyAsn: 1.643 ± 0.037	4.469GlyPro: 4.469 ± 0.063	2.463GlyGln: 2.463 ± 0.05	7.014GlyArg: 7.014 ± 0.074	5.27GlySer: 5.27 ± 0.083	5.591GlyThr: 5.591 ± 0.07	8.018GlyVal: 8.018 ± 0.093	1.533GlyTrp: 1.533 ± 0.037	2.234GlyTyr: 2.234 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	2.399HisAla: 2.399 ± 0.054	0.193HisCys: 0.193 ± 0.012	1.313HisAsp: 1.313 ± 0.035	1.032HisGlu: 1.032 ± 0.029	0.613HisPhe: 0.613 ± 0.022	1.916HisGly: 1.916 ± 0.035	0.61HisHis: 0.61 ± 0.03	0.735HisIle: 0.735 ± 0.024	0.32HisLys: 0.32 ± 0.019	2.021HisLeu: 2.021 ± 0.044	0.362HisMet: 0.362 ± 0.016	0.404HisAsn: 0.404 ± 0.021	1.479HisPro: 1.479 ± 0.032	0.54HisGln: 0.54 ± 0.022	2.026HisArg: 2.026 ± 0.042	1.085HisSer: 1.085 ± 0.029	1.12HisThr: 1.12 ± 0.03	1.682HisVal: 1.682 ± 0.036	0.33HisTrp: 0.33 ± 0.015	0.475HisTyr: 0.475 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	6.586IleAla: 6.586 ± 0.098	0.354IleCys: 0.354 ± 0.02	3.612IleAsp: 3.612 ± 0.051	2.561IleGlu: 2.561 ± 0.048	0.978IlePhe: 0.978 ± 0.029	4.653IleGly: 4.653 ± 0.064	0.752IleHis: 0.752 ± 0.024	1.475IleIle: 1.475 ± 0.04	0.89IleLys: 0.89 ± 0.032	3.233IleLeu: 3.233 ± 0.065	0.603IleMet: 0.603 ± 0.025	0.953IleAsn: 0.953 ± 0.029	2.287IlePro: 2.287 ± 0.054	0.782IleGln: 0.782 ± 0.024	2.681IleArg: 2.681 ± 0.052	2.237IleSer: 2.237 ± 0.049	2.697IleThr: 2.697 ± 0.045	4.052IleVal: 4.052 ± 0.073	0.432IleTrp: 0.432 ± 0.021	0.695IleTyr: 0.695 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	2.697LysAla: 2.697 ± 0.059	0.124LysCys: 0.124 ± 0.008	1.109LysAsp: 1.109 ± 0.034	0.924LysGlu: 0.924 ± 0.03	0.603LysPhe: 0.603 ± 0.025	1.615LysGly: 1.615 ± 0.042	0.461LysHis: 0.461 ± 0.019	1.093LysIle: 1.093 ± 0.03	0.845LysLys: 0.845 ± 0.046	2.074LysLeu: 2.074 ± 0.045	0.5LysMet: 0.5 ± 0.024	0.612LysAsn: 0.612 ± 0.027	1.421LysPro: 1.421 ± 0.047	0.741LysGln: 0.741 ± 0.03	1.638LysArg: 1.638 ± 0.039	1.361LysSer: 1.361 ± 0.037	1.486LysThr: 1.486 ± 0.043	1.984LysVal: 1.984 ± 0.049	0.308LysTrp: 0.308 ± 0.016	0.521LysTyr: 0.521 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	13.606LeuAla: 13.606 ± 0.111	0.707LeuCys: 0.707 ± 0.027	6.662LeuAsp: 6.662 ± 0.107	4.445LeuGlu: 4.445 ± 0.067	2.521LeuPhe: 2.521 ± 0.05	8.532LeuGly: 8.532 ± 0.101	1.881LeuHis: 1.881 ± 0.045	4.335LeuIle: 4.335 ± 0.075	1.805LeuLys: 1.805 ± 0.044	9.005LeuLeu: 9.005 ± 0.119	1.772LeuMet: 1.772 ± 0.04	1.889LeuAsn: 1.889 ± 0.048	5.43LeuPro: 5.43 ± 0.089	2.068LeuGln: 2.068 ± 0.043	7.439LeuArg: 7.439 ± 0.087	5.774LeuSer: 5.774 ± 0.078	6.474LeuThr: 6.474 ± 0.089	8.212LeuVal: 8.212 ± 0.1	1.122LeuTrp: 1.122 ± 0.032	1.663LeuTyr: 1.663 ± 0.04	0.0LeuXaa: 0.0 ± 0.0
Met	2.393MetAla: 2.393 ± 0.048	0.174MetCys: 0.174 ± 0.012	0.926MetAsp: 0.926 ± 0.029	0.744MetGlu: 0.744 ± 0.028	0.589MetPhe: 0.589 ± 0.022	1.447MetGly: 1.447 ± 0.037	0.401MetHis: 0.401 ± 0.018	1.037MetIle: 1.037 ± 0.032	0.518MetLys: 0.518 ± 0.023	1.999MetLeu: 1.999 ± 0.04	0.423MetMet: 0.423 ± 0.02	0.577MetAsn: 0.577 ± 0.024	1.177MetPro: 1.177 ± 0.029	0.507MetGln: 0.507 ± 0.021	1.574MetArg: 1.574 ± 0.036	1.7MetSer: 1.7 ± 0.04	1.949MetThr: 1.949 ± 0.04	1.629MetVal: 1.629 ± 0.035	0.271MetTrp: 0.271 ± 0.016	0.373MetTyr: 0.373 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	2.475AsnAla: 2.475 ± 0.051	0.15AsnCys: 0.15 ± 0.01	1.17AsnAsp: 1.17 ± 0.036	0.998AsnGlu: 0.998 ± 0.031	0.541AsnPhe: 0.541 ± 0.022	1.972AsnGly: 1.972 ± 0.048	0.393AsnHis: 0.393 ± 0.02	0.867AsnIle: 0.867 ± 0.028	0.494AsnLys: 0.494 ± 0.021	1.929AsnLeu: 1.929 ± 0.04	0.364AsnMet: 0.364 ± 0.018	0.473AsnAsn: 0.473 ± 0.022	1.57AsnPro: 1.57 ± 0.039	0.582AsnGln: 0.582 ± 0.022	1.594AsnArg: 1.594 ± 0.041	1.059AsnSer: 1.059 ± 0.033	1.2AsnThr: 1.2 ± 0.033	1.634AsnVal: 1.634 ± 0.046	0.315AsnTrp: 0.315 ± 0.016	0.495AsnTyr: 0.495 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	7.414ProAla: 7.414 ± 0.082	0.262ProCys: 0.262 ± 0.017	4.559ProAsp: 4.559 ± 0.065	3.893ProGlu: 3.893 ± 0.057	1.522ProPhe: 1.522 ± 0.037	5.465ProGly: 5.465 ± 0.069	1.14ProHis: 1.14 ± 0.033	2.196ProIle: 2.196 ± 0.037	1.307ProLys: 1.307 ± 0.036	4.542ProLeu: 4.542 ± 0.064	1.157ProMet: 1.157 ± 0.037	1.123ProAsn: 1.123 ± 0.034	2.759ProPro: 2.759 ± 0.054	1.617ProGln: 1.617 ± 0.045	3.454ProArg: 3.454 ± 0.057	3.166ProSer: 3.166 ± 0.058	3.357ProThr: 3.357 ± 0.062	4.918ProVal: 4.918 ± 0.077	0.775ProTrp: 0.775 ± 0.026	1.012ProTyr: 1.012 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.242GlnAla: 3.242 ± 0.051	0.186GlnCys: 0.186 ± 0.013	1.064GlnAsp: 1.064 ± 0.026	1.126GlnGlu: 1.126 ± 0.034	0.844GlnPhe: 0.844 ± 0.027	1.759GlnGly: 1.759 ± 0.035	0.531GlnHis: 0.531 ± 0.021	1.556GlnIle: 1.556 ± 0.033	0.689GlnLys: 0.689 ± 0.027	2.846GlnLeu: 2.846 ± 0.053	0.711GlnMet: 0.711 ± 0.023	0.614GlnAsn: 0.614 ± 0.024	1.488GlnPro: 1.488 ± 0.041	1.146GlnGln: 1.146 ± 0.041	2.471GlnArg: 2.471 ± 0.049	1.479GlnSer: 1.479 ± 0.035	1.675GlnThr: 1.675 ± 0.034	2.535GlnVal: 2.535 ± 0.049	0.527GlnTrp: 0.527 ± 0.022	0.641GlnTyr: 0.641 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	8.848ArgAla: 8.848 ± 0.094	0.522ArgCys: 0.522 ± 0.025	4.564ArgAsp: 4.564 ± 0.064	4.391ArgGlu: 4.391 ± 0.068	2.325ArgPhe: 2.325 ± 0.044	5.481ArgGly: 5.481 ± 0.065	1.677ArgHis: 1.677 ± 0.043	3.716ArgIle: 3.716 ± 0.053	1.753ArgLys: 1.753 ± 0.041	7.657ArgLeu: 7.657 ± 0.092	1.952ArgMet: 1.952 ± 0.041	1.638ArgAsn: 1.638 ± 0.038	4.291ArgPro: 4.291 ± 0.063	2.04ArgGln: 2.04 ± 0.049	7.29ArgArg: 7.29 ± 0.095	4.419ArgSer: 4.419 ± 0.06	4.584ArgThr: 4.584 ± 0.066	5.984ArgVal: 5.984 ± 0.08	1.308ArgTrp: 1.308 ± 0.032	1.744ArgTyr: 1.744 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	7.461SerAla: 7.461 ± 0.078	0.369SerCys: 0.369 ± 0.019	3.607SerAsp: 3.607 ± 0.061	2.915SerGlu: 2.915 ± 0.047	1.59SerPhe: 1.59 ± 0.035	6.099SerGly: 6.099 ± 0.07	0.987SerHis: 0.987 ± 0.031	2.32SerIle: 2.32 ± 0.044	1.244SerLys: 1.244 ± 0.039	4.928SerLeu: 4.928 ± 0.068	1.372SerMet: 1.372 ± 0.035	1.063SerAsn: 1.063 ± 0.028	3.174SerPro: 3.174 ± 0.049	1.46SerGln: 1.46 ± 0.036	4.0SerArg: 4.0 ± 0.054	3.453SerSer: 3.453 ± 0.063	3.543SerThr: 3.543 ± 0.058	4.895SerVal: 4.895 ± 0.059	0.87SerTrp: 0.87 ± 0.029	1.142SerTyr: 1.142 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	8.312ThrAla: 8.312 ± 0.09	0.384ThrCys: 0.384 ± 0.021	4.094ThrAsp: 4.094 ± 0.062	3.243ThrGlu: 3.243 ± 0.055	1.675ThrPhe: 1.675 ± 0.037	6.163ThrGly: 6.163 ± 0.063	1.147ThrHis: 1.147 ± 0.03	2.389ThrIle: 2.389 ± 0.044	1.182ThrLys: 1.182 ± 0.033	5.284ThrLeu: 5.284 ± 0.068	1.127ThrMet: 1.127 ± 0.03	1.146ThrAsn: 1.146 ± 0.032	3.743ThrPro: 3.743 ± 0.062	1.42ThrGln: 1.42 ± 0.04	3.836ThrArg: 3.836 ± 0.062	3.414ThrSer: 3.414 ± 0.05	3.682ThrThr: 3.682 ± 0.067	6.555ThrVal: 6.555 ± 0.073	0.82ThrTrp: 0.82 ± 0.028	1.277ThrTyr: 1.277 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	11.663ValAla: 11.663 ± 0.125	0.745ValCys: 0.745 ± 0.026	6.23ValAsp: 6.23 ± 0.08	4.983ValGlu: 4.983 ± 0.092	2.638ValPhe: 2.638 ± 0.047	7.278ValGly: 7.278 ± 0.073	1.811ValHis: 1.811 ± 0.037	4.067ValIle: 4.067 ± 0.055	1.765ValLys: 1.765 ± 0.045	8.771ValLeu: 8.771 ± 0.109	1.692ValMet: 1.692 ± 0.037	1.904ValAsn: 1.904 ± 0.038	4.881ValPro: 4.881 ± 0.073	2.014ValGln: 2.014 ± 0.039	6.505ValArg: 6.505 ± 0.086	5.041ValSer: 5.041 ± 0.069	5.749ValThr: 5.749 ± 0.076	8.833ValVal: 8.833 ± 0.104	1.09ValTrp: 1.09 ± 0.032	1.661ValTyr: 1.661 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.476TrpAla: 1.476 ± 0.033	0.142TrpCys: 0.142 ± 0.011	0.79TrpAsp: 0.79 ± 0.023	0.643TrpGlu: 0.643 ± 0.022	0.534TrpPhe: 0.534 ± 0.02	0.947TrpGly: 0.947 ± 0.031	0.333TrpHis: 0.333 ± 0.017	0.738TrpIle: 0.738 ± 0.025	0.317TrpLys: 0.317 ± 0.015	1.502TrpLeu: 1.502 ± 0.039	0.358TrpMet: 0.358 ± 0.017	0.406TrpAsn: 0.406 ± 0.02	0.727TrpPro: 0.727 ± 0.024	0.519TrpGln: 0.519 ± 0.02	1.253TrpArg: 1.253 ± 0.031	0.944TrpSer: 0.944 ± 0.027	0.911TrpThr: 0.911 ± 0.029	1.093TrpVal: 1.093 ± 0.032	0.343TrpTrp: 0.343 ± 0.02	0.313TrpTyr: 0.313 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.28TyrAla: 2.28 ± 0.043	0.175TyrCys: 0.175 ± 0.012	1.396TyrAsp: 1.396 ± 0.039	1.043TyrGlu: 1.043 ± 0.027	0.701TyrPhe: 0.701 ± 0.026	1.988TyrGly: 1.988 ± 0.037	0.362TyrHis: 0.362 ± 0.015	0.655TyrIle: 0.655 ± 0.024	0.39TyrLys: 0.39 ± 0.02	2.234TyrLeu: 2.234 ± 0.044	0.289TyrMet: 0.289 ± 0.018	0.412TyrAsn: 0.412 ± 0.02	1.085TyrPro: 1.085 ± 0.026	0.614TyrGln: 0.614 ± 0.022	1.976TyrArg: 1.976 ± 0.039	1.262TyrSer: 1.262 ± 0.039	1.153TyrThr: 1.153 ± 0.031	1.633TyrVal: 1.633 ± 0.038	0.361TyrTrp: 0.361 ± 0.017	0.47TyrTyr: 0.47 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3903 proteins (1261255 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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