Amino acid dipepetide frequency for Salmonella arizonae (strain ATCC BAA-731 / CDC346-86 / RSK2980)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.734AlaAla: 9.734 ± 0.137	1.2AlaCys: 1.2 ± 0.033	4.911AlaAsp: 4.911 ± 0.067	5.409AlaGlu: 5.409 ± 0.081	3.603AlaPhe: 3.603 ± 0.065	7.377AlaGly: 7.377 ± 0.1	1.892AlaHis: 1.892 ± 0.038	5.857AlaIle: 5.857 ± 0.081	3.897AlaLys: 3.897 ± 0.06	11.41AlaLeu: 11.41 ± 0.125	2.977AlaMet: 2.977 ± 0.051	3.141AlaAsn: 3.141 ± 0.053	3.655AlaPro: 3.655 ± 0.065	4.438AlaGln: 4.438 ± 0.078	5.533AlaArg: 5.533 ± 0.089	5.385AlaSer: 5.385 ± 0.069	4.913AlaThr: 4.913 ± 0.082	6.453AlaVal: 6.453 ± 0.08	1.602AlaTrp: 1.602 ± 0.037	2.008AlaTyr: 2.008 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	1.055CysAla: 1.055 ± 0.031	0.188CysCys: 0.188 ± 0.014	0.642CysAsp: 0.642 ± 0.021	0.644CysGlu: 0.644 ± 0.021	0.495CysPhe: 0.495 ± 0.02	1.094CysGly: 1.094 ± 0.032	0.359CysHis: 0.359 ± 0.019	0.654CysIle: 0.654 ± 0.025	0.361CysLys: 0.361 ± 0.019	1.064CysLeu: 1.064 ± 0.032	0.243CysMet: 0.243 ± 0.016	0.358CysAsn: 0.358 ± 0.017	0.547CysPro: 0.547 ± 0.024	0.511CysGln: 0.511 ± 0.022	0.675CysArg: 0.675 ± 0.026	0.714CysSer: 0.714 ± 0.024	0.496CysThr: 0.496 ± 0.016	0.775CysVal: 0.775 ± 0.025	0.218CysTrp: 0.218 ± 0.014	0.372CysTyr: 0.372 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	5.336AspAla: 5.336 ± 0.062	0.5AspCys: 0.5 ± 0.021	3.004AspAsp: 3.004 ± 0.059	3.475AspGlu: 3.475 ± 0.063	2.112AspPhe: 2.112 ± 0.04	3.785AspGly: 3.785 ± 0.078	1.006AspHis: 1.006 ± 0.027	3.652AspIle: 3.652 ± 0.06	2.667AspLys: 2.667 ± 0.046	4.539AspLeu: 4.539 ± 0.064	1.358AspMet: 1.358 ± 0.035	2.435AspAsn: 2.435 ± 0.054	2.166AspPro: 2.166 ± 0.048	1.478AspGln: 1.478 ± 0.036	2.577AspArg: 2.577 ± 0.045	2.891AspSer: 2.891 ± 0.065	2.723AspThr: 2.723 ± 0.084	3.781AspVal: 3.781 ± 0.071	0.811AspTrp: 0.811 ± 0.029	1.915AspTyr: 1.915 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	5.146GluAla: 5.146 ± 0.085	0.517GluCys: 0.517 ± 0.023	2.419GluAsp: 2.419 ± 0.048	3.354GluGlu: 3.354 ± 0.057	1.831GluPhe: 1.831 ± 0.039	3.615GluGly: 3.615 ± 0.048	1.414GluHis: 1.414 ± 0.033	3.343GluIle: 3.343 ± 0.053	3.434GluLys: 3.434 ± 0.055	5.765GluLeu: 5.765 ± 0.081	1.815GluMet: 1.815 ± 0.041	2.5GluAsn: 2.5 ± 0.047	2.028GluPro: 2.028 ± 0.044	3.215GluGln: 3.215 ± 0.055	3.646GluArg: 3.646 ± 0.074	2.94GluSer: 2.94 ± 0.05	2.99GluThr: 2.99 ± 0.047	3.586GluVal: 3.586 ± 0.061	0.762GluTrp: 0.762 ± 0.021	1.596GluTyr: 1.596 ± 0.043	0.0GluXaa: 0.0 ± 0.0
Phe	3.65PheAla: 3.65 ± 0.062	0.608PheCys: 0.608 ± 0.023	2.325PheAsp: 2.325 ± 0.047	1.765PheGlu: 1.765 ± 0.04	1.832PhePhe: 1.832 ± 0.049	3.079PheGly: 3.079 ± 0.056	0.903PheHis: 0.903 ± 0.031	2.734PheIle: 2.734 ± 0.057	1.354PheLys: 1.354 ± 0.038	3.473PheLeu: 3.473 ± 0.065	1.042PheMet: 1.042 ± 0.032	1.794PheAsn: 1.794 ± 0.035	1.524PhePro: 1.524 ± 0.035	1.138PheGln: 1.138 ± 0.03	1.985PheArg: 1.985 ± 0.044	3.183PheSer: 3.183 ± 0.052	2.633PheThr: 2.633 ± 0.066	2.469PheVal: 2.469 ± 0.051	0.65PheTrp: 0.65 ± 0.026	1.273PheTyr: 1.273 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	6.105GlyAla: 6.105 ± 0.083	1.015GlyCys: 1.015 ± 0.03	3.74GlyAsp: 3.74 ± 0.065	4.455GlyGlu: 4.455 ± 0.071	3.173GlyPhe: 3.173 ± 0.057	5.279GlyGly: 5.279 ± 0.076	1.613GlyHis: 1.613 ± 0.039	5.015GlyIle: 5.015 ± 0.075	4.018GlyLys: 4.018 ± 0.063	7.191GlyLeu: 7.191 ± 0.091	2.344GlyMet: 2.344 ± 0.049	2.961GlyAsn: 2.961 ± 0.089	1.994GlyPro: 1.994 ± 0.039	2.858GlyGln: 2.858 ± 0.05	3.728GlyArg: 3.728 ± 0.055	3.927GlySer: 3.927 ± 0.059	3.652GlyThr: 3.652 ± 0.071	5.767GlyVal: 5.767 ± 0.067	1.251GlyTrp: 1.251 ± 0.034	2.626GlyTyr: 2.626 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	1.89HisAla: 1.89 ± 0.041	0.336HisCys: 0.336 ± 0.016	1.19HisAsp: 1.19 ± 0.034	1.148HisGlu: 1.148 ± 0.026	1.14HisPhe: 1.14 ± 0.032	1.71HisGly: 1.71 ± 0.042	0.794HisHis: 0.794 ± 0.024	1.433HisIle: 1.433 ± 0.036	0.785HisLys: 0.785 ± 0.025	2.309HisLeu: 2.309 ± 0.048	0.593HisMet: 0.593 ± 0.019	0.9HisAsn: 0.9 ± 0.032	1.316HisPro: 1.316 ± 0.028	1.165HisGln: 1.165 ± 0.029	1.257HisArg: 1.257 ± 0.032	1.248HisSer: 1.248 ± 0.031	1.147HisThr: 1.147 ± 0.027	1.31HisVal: 1.31 ± 0.033	0.39HisTrp: 0.39 ± 0.019	0.976HisTyr: 0.976 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	6.487IleAla: 6.487 ± 0.074	0.727IleCys: 0.727 ± 0.022	3.608IleAsp: 3.608 ± 0.084	3.295IleGlu: 3.295 ± 0.062	2.214IlePhe: 2.214 ± 0.049	4.497IleGly: 4.497 ± 0.077	1.293IleHis: 1.293 ± 0.029	3.719IleIle: 3.719 ± 0.06	2.52IleLys: 2.52 ± 0.049	5.212IleLeu: 5.212 ± 0.077	1.396IleMet: 1.396 ± 0.037	2.838IleAsn: 2.838 ± 0.051	2.788IlePro: 2.788 ± 0.049	1.926IleGln: 1.926 ± 0.044	3.121IleArg: 3.121 ± 0.047	3.877IleSer: 3.877 ± 0.059	3.792IleThr: 3.792 ± 0.079	4.077IleVal: 4.077 ± 0.058	0.76IleTrp: 0.76 ± 0.025	1.637IleTyr: 1.637 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.256LysAla: 4.256 ± 0.073	0.339LysCys: 0.339 ± 0.016	2.106LysAsp: 2.106 ± 0.046	2.579LysGlu: 2.579 ± 0.041	1.191LysPhe: 1.191 ± 0.031	3.049LysGly: 3.049 ± 0.052	0.909LysHis: 0.909 ± 0.026	2.558LysIle: 2.558 ± 0.045	2.457LysLys: 2.457 ± 0.048	4.329LysLeu: 4.329 ± 0.065	1.327LysMet: 1.327 ± 0.035	1.961LysAsn: 1.961 ± 0.041	2.18LysPro: 2.18 ± 0.044	1.936LysGln: 1.936 ± 0.039	2.672LysArg: 2.672 ± 0.055	2.395LysSer: 2.395 ± 0.046	2.718LysThr: 2.718 ± 0.049	2.938LysVal: 2.938 ± 0.056	0.477LysTrp: 0.477 ± 0.021	1.277LysTyr: 1.277 ± 0.032	0.0LysXaa: 0.0 ± 0.0
Leu	10.934LeuAla: 10.934 ± 0.12	1.297LeuCys: 1.297 ± 0.04	5.324LeuAsp: 5.324 ± 0.072	5.453LeuGlu: 5.453 ± 0.085	4.375LeuPhe: 4.375 ± 0.088	6.762LeuGly: 6.762 ± 0.087	2.326LeuHis: 2.326 ± 0.034	5.931LeuIle: 5.931 ± 0.087	4.673LeuLys: 4.673 ± 0.071	11.713LeuLeu: 11.713 ± 0.14	2.952LeuMet: 2.952 ± 0.059	4.447LeuAsn: 4.447 ± 0.058	5.67LeuPro: 5.67 ± 0.085	4.005LeuGln: 4.005 ± 0.062	6.226LeuArg: 6.226 ± 0.09	7.227LeuSer: 7.227 ± 0.089	6.576LeuThr: 6.576 ± 0.094	6.723LeuVal: 6.723 ± 0.077	1.449LeuTrp: 1.449 ± 0.044	2.692LeuTyr: 2.692 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.93MetAla: 2.93 ± 0.058	0.226MetCys: 0.226 ± 0.014	1.188MetAsp: 1.188 ± 0.026	1.284MetGlu: 1.284 ± 0.032	0.942MetPhe: 0.942 ± 0.031	1.939MetGly: 1.939 ± 0.039	0.538MetHis: 0.538 ± 0.021	1.504MetIle: 1.504 ± 0.035	1.434MetLys: 1.434 ± 0.033	3.162MetLeu: 3.162 ± 0.057	0.957MetMet: 0.957 ± 0.029	1.117MetAsn: 1.117 ± 0.033	1.416MetPro: 1.416 ± 0.033	1.238MetGln: 1.238 ± 0.035	1.569MetArg: 1.569 ± 0.034	1.808MetSer: 1.808 ± 0.031	1.792MetThr: 1.792 ± 0.034	1.956MetVal: 1.956 ± 0.04	0.281MetTrp: 0.281 ± 0.015	0.559MetTyr: 0.559 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	3.726AsnAla: 3.726 ± 0.062	0.393AsnCys: 0.393 ± 0.017	2.193AsnAsp: 2.193 ± 0.049	2.024AsnGlu: 2.024 ± 0.043	1.407AsnPhe: 1.407 ± 0.033	3.21AsnGly: 3.21 ± 0.062	0.924AsnHis: 0.924 ± 0.027	2.654AsnIle: 2.654 ± 0.064	1.706AsnLys: 1.706 ± 0.046	3.573AsnLeu: 3.573 ± 0.052	1.015AsnMet: 1.015 ± 0.028	1.768AsnAsn: 1.768 ± 0.053	2.111AsnPro: 2.111 ± 0.042	1.617AsnGln: 1.617 ± 0.042	2.078AsnArg: 2.078 ± 0.039	2.119AsnSer: 2.119 ± 0.044	2.217AsnThr: 2.217 ± 0.055	2.745AsnVal: 2.745 ± 0.055	0.587AsnTrp: 0.587 ± 0.026	1.287AsnTyr: 1.287 ± 0.037	0.0AsnXaa: 0.0 ± 0.0
Pro	4.393ProAla: 4.393 ± 0.057	0.407ProCys: 0.407 ± 0.021	2.881ProAsp: 2.881 ± 0.055	3.348ProGlu: 3.348 ± 0.061	1.844ProPhe: 1.844 ± 0.044	3.511ProGly: 3.511 ± 0.051	1.035ProHis: 1.035 ± 0.03	1.854ProIle: 1.854 ± 0.042	1.522ProLys: 1.522 ± 0.037	5.09ProLeu: 5.09 ± 0.066	1.04ProMet: 1.04 ± 0.027	1.276ProAsn: 1.276 ± 0.035	1.749ProPro: 1.749 ± 0.043	2.177ProGln: 2.177 ± 0.046	1.989ProArg: 1.989 ± 0.045	2.099ProSer: 2.099 ± 0.042	2.178ProThr: 2.178 ± 0.059	3.968ProVal: 3.968 ± 0.064	0.757ProTrp: 0.757 ± 0.027	1.279ProTyr: 1.279 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	4.477GlnAla: 4.477 ± 0.068	0.402GlnCys: 0.402 ± 0.019	1.759GlnAsp: 1.759 ± 0.036	2.246GlnGlu: 2.246 ± 0.04	1.526GlnPhe: 1.526 ± 0.034	2.948GlnGly: 2.948 ± 0.052	1.194GlnHis: 1.194 ± 0.039	2.363GlnIle: 2.363 ± 0.041	1.886GlnLys: 1.886 ± 0.035	4.801GlnLeu: 4.801 ± 0.073	1.198GlnMet: 1.198 ± 0.026	1.572GlnAsn: 1.572 ± 0.039	2.085GlnPro: 2.085 ± 0.047	3.087GlnGln: 3.087 ± 0.07	2.982GlnArg: 2.982 ± 0.064	2.293GlnSer: 2.293 ± 0.047	2.316GlnThr: 2.316 ± 0.045	2.778GlnVal: 2.778 ± 0.042	0.703GlnTrp: 0.703 ± 0.025	1.237GlnTyr: 1.237 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	4.513ArgAla: 4.513 ± 0.065	0.651ArgCys: 0.651 ± 0.02	3.03ArgAsp: 3.03 ± 0.06	3.796ArgGlu: 3.796 ± 0.066	2.672ArgPhe: 2.672 ± 0.047	3.214ArgGly: 3.214 ± 0.055	1.668ArgHis: 1.668 ± 0.042	3.446ArgIle: 3.446 ± 0.063	2.461ArgLys: 2.461 ± 0.057	6.532ArgLeu: 6.532 ± 0.096	1.62ArgMet: 1.62 ± 0.034	2.106ArgAsn: 2.106 ± 0.04	2.238ArgPro: 2.238 ± 0.046	3.158ArgGln: 3.158 ± 0.061	3.582ArgArg: 3.582 ± 0.07	2.685ArgSer: 2.685 ± 0.052	2.592ArgThr: 2.592 ± 0.05	3.726ArgVal: 3.726 ± 0.056	1.004ArgTrp: 1.004 ± 0.027	2.27ArgTyr: 2.27 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	5.574SerAla: 5.574 ± 0.078	0.636SerCys: 0.636 ± 0.026	3.111SerAsp: 3.111 ± 0.049	3.158SerGlu: 3.158 ± 0.051	2.338SerPhe: 2.338 ± 0.048	5.202SerGly: 5.202 ± 0.073	1.404SerHis: 1.404 ± 0.034	3.091SerIle: 3.091 ± 0.059	2.072SerLys: 2.072 ± 0.049	6.597SerLeu: 6.597 ± 0.085	1.468SerMet: 1.468 ± 0.035	1.875SerAsn: 1.875 ± 0.038	2.593SerPro: 2.593 ± 0.052	2.545SerGln: 2.545 ± 0.045	3.389SerArg: 3.389 ± 0.059	3.452SerSer: 3.452 ± 0.058	3.0SerThr: 3.0 ± 0.066	4.196SerVal: 4.196 ± 0.054	0.959SerTrp: 0.959 ± 0.029	1.658SerTyr: 1.658 ± 0.042	0.0SerXaa: 0.0 ± 0.0
Thr	5.038ThrAla: 5.038 ± 0.087	0.577ThrCys: 0.577 ± 0.023	2.759ThrAsp: 2.759 ± 0.061	2.727ThrGlu: 2.727 ± 0.053	2.171ThrPhe: 2.171 ± 0.044	4.608ThrGly: 4.608 ± 0.07	1.317ThrHis: 1.317 ± 0.036	3.178ThrIle: 3.178 ± 0.084	1.606ThrLys: 1.606 ± 0.036	7.609ThrLeu: 7.609 ± 0.104	1.191ThrMet: 1.191 ± 0.031	1.722ThrAsn: 1.722 ± 0.06	3.332ThrPro: 3.332 ± 0.056	2.288ThrGln: 2.288 ± 0.051	3.097ThrArg: 3.097 ± 0.043	2.956ThrSer: 2.956 ± 0.066	2.991ThrThr: 2.991 ± 0.073	4.004ThrVal: 4.004 ± 0.103	0.846ThrTrp: 0.846 ± 0.033	1.244ThrTyr: 1.244 ± 0.036	0.0ThrXaa: 0.0 ± 0.0
Val	6.675ValAla: 6.675 ± 0.081	0.84ValCys: 0.84 ± 0.027	3.705ValAsp: 3.705 ± 0.058	3.862ValGlu: 3.862 ± 0.069	2.584ValPhe: 2.584 ± 0.046	4.672ValGly: 4.672 ± 0.066	1.231ValHis: 1.231 ± 0.032	4.506ValIle: 4.506 ± 0.065	3.182ValLys: 3.182 ± 0.051	6.982ValLeu: 6.982 ± 0.081	2.186ValMet: 2.186 ± 0.038	2.96ValAsn: 2.96 ± 0.062	2.955ValPro: 2.955 ± 0.053	2.293ValGln: 2.293 ± 0.039	3.689ValArg: 3.689 ± 0.052	4.455ValSer: 4.455 ± 0.056	4.308ValThr: 4.308 ± 0.101	5.476ValVal: 5.476 ± 0.083	0.988ValTrp: 0.988 ± 0.031	1.783ValTyr: 1.783 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.004TrpAla: 1.004 ± 0.028	0.202TrpCys: 0.202 ± 0.012	0.622TrpAsp: 0.622 ± 0.023	0.593TrpGlu: 0.593 ± 0.02	0.705TrpPhe: 0.705 ± 0.027	0.882TrpGly: 0.882 ± 0.026	0.467TrpHis: 0.467 ± 0.02	0.775TrpIle: 0.775 ± 0.023	0.55TrpLys: 0.55 ± 0.021	2.357TrpLeu: 2.357 ± 0.058	0.454TrpMet: 0.454 ± 0.02	0.487TrpAsn: 0.487 ± 0.02	0.655TrpPro: 0.655 ± 0.026	1.159TrpGln: 1.159 ± 0.034	1.209TrpArg: 1.209 ± 0.031	0.83TrpSer: 0.83 ± 0.028	0.624TrpThr: 0.624 ± 0.024	0.939TrpVal: 0.939 ± 0.034	0.231TrpTrp: 0.231 ± 0.015	0.435TrpTyr: 0.435 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.473TyrAla: 2.473 ± 0.052	0.401TyrCys: 0.401 ± 0.017	1.695TyrAsp: 1.695 ± 0.049	1.3TyrGlu: 1.3 ± 0.033	1.261TyrPhe: 1.261 ± 0.034	2.278TyrGly: 2.278 ± 0.048	0.753TyrHis: 0.753 ± 0.025	1.519TyrIle: 1.519 ± 0.04	1.069TyrLys: 1.069 ± 0.031	3.048TyrLeu: 3.048 ± 0.052	0.663TyrMet: 0.663 ± 0.024	1.135TyrAsn: 1.135 ± 0.032	1.394TyrPro: 1.394 ± 0.036	1.624TyrGln: 1.624 ± 0.039	1.962TyrArg: 1.962 ± 0.043	1.832TyrSer: 1.832 ± 0.04	1.602TyrThr: 1.602 ± 0.05	1.662TyrVal: 1.662 ± 0.036	0.455TyrTrp: 0.455 ± 0.02	1.032TyrTyr: 1.032 ± 0.036	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4500 proteins (1329514 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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