Amino acid dipepetide frequency for Beihai picorna-like virus 53

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.295AlaAla: 5.295 ± 0.01
0.353AlaCys: 0.353 ± 0.316
1.412AlaAsp: 1.412 ± 0.213
6.001AlaGlu: 6.001 ± 0.117
2.824AlaPhe: 2.824 ± 0.426
4.942AlaGly: 4.942 ± 0.22
1.765AlaHis: 1.765 ± 0.529
3.883AlaIle: 3.883 ± 0.203
2.824AlaLys: 2.824 ± 1.151
4.236AlaLeu: 4.236 ± 0.113
3.53AlaMet: 3.53 ± 0.395
3.177AlaAsn: 3.177 ± 1.794
5.648AlaPro: 5.648 ± 2.956
1.059AlaGln: 1.059 ± 0.103
3.883AlaArg: 3.883 ± 1.255
3.53AlaSer: 3.53 ± 0.533
6.354AlaThr: 6.354 ± 1.485
6.354AlaVal: 6.354 ± 0.433
1.059AlaTrp: 1.059 ± 0.949
2.471AlaTyr: 2.471 ± 0.636
0.0AlaXaa: 0.0 ± 0.0
Cys
1.059CysAla: 1.059 ± 0.423
0.706CysCys: 0.706 ± 0.419
0.706CysAsp: 0.706 ± 0.419
1.412CysGlu: 1.412 ± 0.213
0.0CysPhe: 0.0 ± 0.0
2.118CysGly: 2.118 ± 0.732
0.0CysHis: 0.0 ± 0.0
0.706CysIle: 0.706 ± 0.419
1.059CysLys: 1.059 ± 0.423
1.059CysLeu: 1.059 ± 0.103
0.353CysMet: 0.353 ± 0.21
1.412CysAsn: 1.412 ± 0.213
1.412CysPro: 1.412 ± 0.313
0.706CysGln: 0.706 ± 0.632
1.059CysArg: 1.059 ± 0.423
1.765CysSer: 1.765 ± 0.003
1.059CysThr: 1.059 ± 0.103
1.059CysVal: 1.059 ± 0.629
0.0CysTrp: 0.0 ± 0.0
1.059CysTyr: 1.059 ± 0.103
0.0CysXaa: 0.0 ± 0.0
Asp
4.942AspAla: 4.942 ± 0.306
0.706AspCys: 0.706 ± 0.419
3.53AspAsp: 3.53 ± 0.007
5.648AspGlu: 5.648 ± 1.251
2.824AspPhe: 2.824 ± 1.478
2.824AspGly: 2.824 ± 0.426
1.059AspHis: 1.059 ± 0.103
2.824AspIle: 2.824 ± 2.004
2.824AspLys: 2.824 ± 0.626
3.177AspLeu: 3.177 ± 0.309
0.706AspMet: 0.706 ± 0.107
3.177AspAsn: 3.177 ± 0.217
2.471AspPro: 2.471 ± 1.162
1.765AspGln: 1.765 ± 1.048
2.118AspArg: 2.118 ± 1.258
3.53AspSer: 3.53 ± 0.519
3.53AspThr: 3.53 ± 0.533
3.53AspVal: 3.53 ± 1.045
0.0AspTrp: 0.0 ± 0.0
3.883AspTyr: 3.883 ± 0.203
0.0AspXaa: 0.0 ± 0.0
Glu
4.236GluAla: 4.236 ± 0.412
1.412GluCys: 1.412 ± 0.213
4.942GluAsp: 4.942 ± 1.272
5.648GluGlu: 5.648 ± 0.327
3.883GluPhe: 3.883 ± 1.255
3.883GluGly: 3.883 ± 0.203
1.765GluHis: 1.765 ± 0.529
6.354GluIle: 6.354 ± 2.196
3.883GluLys: 3.883 ± 1.255
3.53GluLeu: 3.53 ± 0.533
2.471GluMet: 2.471 ± 0.416
2.118GluAsn: 2.118 ± 0.206
2.824GluPro: 2.824 ± 0.426
2.471GluGln: 2.471 ± 0.416
4.589GluArg: 4.589 ± 0.43
3.53GluSer: 3.53 ± 0.007
2.824GluThr: 2.824 ± 1.151
4.589GluVal: 4.589 ± 0.096
1.765GluTrp: 1.765 ± 0.522
0.706GluTyr: 0.706 ± 0.632
0.0GluXaa: 0.0 ± 0.0
Phe
3.883PheAla: 3.883 ± 0.849
1.412PheCys: 1.412 ± 0.213
1.412PheAsp: 1.412 ± 0.839
3.177PheGlu: 3.177 ± 0.742
3.53PhePhe: 3.53 ± 0.519
2.824PheGly: 2.824 ± 0.1
1.059PheHis: 1.059 ± 0.629
2.824PheIle: 2.824 ± 1.151
2.471PheLys: 2.471 ± 0.636
4.589PheLeu: 4.589 ± 1.481
1.412PheMet: 1.412 ± 0.313
2.824PheAsn: 2.824 ± 0.626
1.412PhePro: 1.412 ± 0.313
1.059PheGln: 1.059 ± 0.423
1.765PheArg: 1.765 ± 0.522
4.589PheSer: 4.589 ± 0.956
0.706PheThr: 0.706 ± 0.107
2.471PheVal: 2.471 ± 0.11
0.353PheTrp: 0.353 ± 0.21
2.118PheTyr: 2.118 ± 0.732
0.0PheXaa: 0.0 ± 0.0
Gly
3.177GlyAla: 3.177 ± 1.794
1.059GlyCys: 1.059 ± 0.103
3.883GlyAsp: 3.883 ± 0.323
4.236GlyGlu: 4.236 ± 0.938
3.53GlyPhe: 3.53 ± 0.533
4.942GlyGly: 4.942 ± 1.272
1.412GlyHis: 1.412 ± 0.213
3.53GlyIle: 3.53 ± 0.519
2.824GlyLys: 2.824 ± 0.626
5.295GlyLeu: 5.295 ± 1.041
2.471GlyMet: 2.471 ± 0.416
4.236GlyAsn: 4.236 ± 1.691
3.177GlyPro: 3.177 ± 0.309
1.412GlyGln: 1.412 ± 0.213
2.824GlyArg: 2.824 ± 0.1
5.295GlySer: 5.295 ± 1.062
4.589GlyThr: 4.589 ± 2.007
5.295GlyVal: 5.295 ± 2.114
0.706GlyTrp: 0.706 ± 0.107
3.53GlyTyr: 3.53 ± 0.519
0.0GlyXaa: 0.0 ± 0.0
His
1.412HisAla: 1.412 ± 1.265
0.706HisCys: 0.706 ± 0.632
0.353HisAsp: 0.353 ± 0.21
1.059HisGlu: 1.059 ± 0.423
1.059HisPhe: 1.059 ± 0.423
0.353HisGly: 0.353 ± 0.316
0.706HisHis: 0.706 ± 0.107
1.059HisIle: 1.059 ± 0.103
0.706HisLys: 0.706 ± 0.419
1.059HisLeu: 1.059 ± 0.949
1.412HisMet: 1.412 ± 0.839
0.353HisAsn: 0.353 ± 0.21
0.706HisPro: 0.706 ± 0.419
1.412HisGln: 1.412 ± 0.313
1.059HisArg: 1.059 ± 0.103
1.765HisSer: 1.765 ± 1.048
0.706HisThr: 0.706 ± 0.107
3.177HisVal: 3.177 ± 0.217
0.353HisTrp: 0.353 ± 0.316
0.706HisTyr: 0.706 ± 0.419
0.0HisXaa: 0.0 ± 0.0
Ile
4.942IleAla: 4.942 ± 1.272
0.706IleCys: 0.706 ± 0.107
4.589IleAsp: 4.589 ± 0.622
1.765IleGlu: 1.765 ± 0.529
1.765IlePhe: 1.765 ± 0.522
4.236IleGly: 4.236 ± 1.165
0.706IleHis: 0.706 ± 0.419
3.53IleIle: 3.53 ± 0.533
2.471IleLys: 2.471 ± 0.942
3.883IleLeu: 3.883 ± 1.78
1.412IleMet: 1.412 ± 0.839
2.824IleAsn: 2.824 ± 0.426
2.471IlePro: 2.471 ± 1.162
0.706IleGln: 0.706 ± 0.107
1.412IleArg: 1.412 ± 0.313
7.413IleSer: 7.413 ± 0.722
2.824IleThr: 2.824 ± 0.426
5.295IleVal: 5.295 ± 1.041
0.0IleTrp: 0.0 ± 0.0
1.412IleTyr: 1.412 ± 0.839
0.0IleXaa: 0.0 ± 0.0
Lys
2.118LysAla: 2.118 ± 0.732
0.353LysCys: 0.353 ± 0.21
3.177LysAsp: 3.177 ± 0.835
4.942LysGlu: 4.942 ± 1.358
2.118LysPhe: 2.118 ± 1.258
3.883LysGly: 3.883 ± 1.255
0.0LysHis: 0.0 ± 0.0
2.118LysIle: 2.118 ± 0.846
5.648LysLys: 5.648 ± 3.355
3.177LysLeu: 3.177 ± 1.887
2.471LysMet: 2.471 ± 0.11
3.53LysAsn: 3.53 ± 1.571
3.53LysPro: 3.53 ± 1.045
1.412LysGln: 1.412 ± 0.839
3.53LysArg: 3.53 ± 0.533
2.824LysSer: 2.824 ± 0.626
0.706LysThr: 0.706 ± 0.107
3.883LysVal: 3.883 ± 1.78
0.0LysTrp: 0.0 ± 0.0
2.824LysTyr: 2.824 ± 1.151
0.0LysXaa: 0.0 ± 0.0
Leu
7.06LeuAla: 7.06 ± 0.014
1.765LeuCys: 1.765 ± 0.522
5.295LeuAsp: 5.295 ± 1.041
4.236LeuGlu: 4.236 ± 0.938
2.118LeuPhe: 2.118 ± 0.206
2.824LeuGly: 2.824 ± 0.1
1.765LeuHis: 1.765 ± 0.003
5.648LeuIle: 5.648 ± 0.327
4.942LeuLys: 4.942 ± 1.358
2.471LeuLeu: 2.471 ± 0.416
2.824LeuMet: 2.824 ± 1.787
3.177LeuAsn: 3.177 ± 0.309
3.883LeuPro: 3.883 ± 0.323
2.118LeuGln: 2.118 ± 1.371
3.883LeuArg: 3.883 ± 0.729
7.413LeuSer: 7.413 ± 1.248
3.883LeuThr: 3.883 ± 0.729
5.295LeuVal: 5.295 ± 0.01
1.412LeuTrp: 1.412 ± 0.739
0.706LeuTyr: 0.706 ± 0.107
0.0LeuXaa: 0.0 ± 0.0
Met
3.177MetAla: 3.177 ± 0.309
0.0MetCys: 0.0 ± 0.0
1.059MetAsp: 1.059 ± 0.629
1.412MetGlu: 1.412 ± 0.313
1.059MetPhe: 1.059 ± 0.423
1.765MetGly: 1.765 ± 0.003
0.353MetHis: 0.353 ± 0.21
2.118MetIle: 2.118 ± 0.732
1.412MetLys: 1.412 ± 0.313
1.765MetLeu: 1.765 ± 0.003
0.706MetMet: 0.706 ± 0.419
1.412MetAsn: 1.412 ± 0.213
1.765MetPro: 1.765 ± 1.048
3.53MetGln: 3.53 ± 0.519
2.471MetArg: 2.471 ± 0.416
0.706MetSer: 0.706 ± 0.419
2.824MetThr: 2.824 ± 0.1
3.177MetVal: 3.177 ± 0.835
0.0MetTrp: 0.0 ± 0.0
1.059MetTyr: 1.059 ± 0.629
0.0MetXaa: 0.0 ± 0.0
Asn
2.824AsnAla: 2.824 ± 0.626
1.765AsnCys: 1.765 ± 0.003
3.53AsnAsp: 3.53 ± 1.059
3.177AsnGlu: 3.177 ± 0.309
1.412AsnPhe: 1.412 ± 0.313
4.589AsnGly: 4.589 ± 1.481
2.118AsnHis: 2.118 ± 0.846
2.824AsnIle: 2.824 ± 0.952
2.118AsnLys: 2.118 ± 1.258
4.236AsnLeu: 4.236 ± 0.113
1.059AsnMet: 1.059 ± 0.629
1.412AsnAsn: 1.412 ± 0.213
1.765AsnPro: 1.765 ± 0.529
1.059AsnGln: 1.059 ± 0.103
1.059AsnArg: 1.059 ± 0.423
1.765AsnSer: 1.765 ± 0.003
4.236AsnThr: 4.236 ± 1.691
3.53AsnVal: 3.53 ± 1.045
0.706AsnTrp: 0.706 ± 0.107
2.471AsnTyr: 2.471 ± 1.162
0.0AsnXaa: 0.0 ± 0.0
Pro
3.53ProAla: 3.53 ± 2.11
0.706ProCys: 0.706 ± 0.632
2.824ProAsp: 2.824 ± 0.952
5.295ProGlu: 5.295 ± 2.093
2.118ProPhe: 2.118 ± 0.846
4.589ProGly: 4.589 ± 2.533
1.059ProHis: 1.059 ± 0.103
1.412ProIle: 1.412 ± 0.839
2.824ProLys: 2.824 ± 1.151
3.53ProLeu: 3.53 ± 0.533
2.824ProMet: 2.824 ± 0.626
2.118ProAsn: 2.118 ± 0.32
3.53ProPro: 3.53 ± 1.059
3.53ProGln: 3.53 ± 0.533
1.412ProArg: 1.412 ± 0.739
7.06ProSer: 7.06 ± 1.065
2.471ProThr: 2.471 ± 0.636
3.177ProVal: 3.177 ± 0.217
1.059ProTrp: 1.059 ± 0.949
1.412ProTyr: 1.412 ± 0.313
0.0ProXaa: 0.0 ± 0.0
Gln
2.118GlnAla: 2.118 ± 0.206
0.353GlnCys: 0.353 ± 0.316
1.765GlnAsp: 1.765 ± 0.529
2.824GlnGlu: 2.824 ± 0.626
2.471GlnPhe: 2.471 ± 0.416
4.236GlnGly: 4.236 ± 1.165
0.353GlnHis: 0.353 ± 0.21
2.471GlnIle: 2.471 ± 0.416
1.412GlnLys: 1.412 ± 0.313
3.883GlnLeu: 3.883 ± 0.729
0.353GlnMet: 0.353 ± 0.316
0.706GlnAsn: 0.706 ± 0.632
0.706GlnPro: 0.706 ± 0.419
1.059GlnGln: 1.059 ± 0.103
1.059GlnArg: 1.059 ± 0.949
2.118GlnSer: 2.118 ± 0.32
1.059GlnThr: 1.059 ± 0.949
1.765GlnVal: 1.765 ± 0.529
0.706GlnTrp: 0.706 ± 0.419
1.059GlnTyr: 1.059 ± 0.423
0.0GlnXaa: 0.0 ± 0.0
Arg
2.824ArgAla: 2.824 ± 0.426
1.059ArgCys: 1.059 ± 0.629
3.177ArgAsp: 3.177 ± 0.835
3.883ArgGlu: 3.883 ± 0.203
2.471ArgPhe: 2.471 ± 0.416
4.236ArgGly: 4.236 ± 0.113
1.765ArgHis: 1.765 ± 1.048
1.059ArgIle: 1.059 ± 0.103
0.706ArgLys: 0.706 ± 0.419
3.177ArgLeu: 3.177 ± 0.217
1.412ArgMet: 1.412 ± 0.213
2.471ArgAsn: 2.471 ± 0.942
2.471ArgPro: 2.471 ± 0.11
0.706ArgGln: 0.706 ± 0.107
3.883ArgArg: 3.883 ± 1.78
1.765ArgSer: 1.765 ± 0.003
2.824ArgThr: 2.824 ± 0.626
4.942ArgVal: 4.942 ± 0.746
0.353ArgTrp: 0.353 ± 0.316
2.824ArgTyr: 2.824 ± 0.426
0.0ArgXaa: 0.0 ± 0.0
Ser
6.707SerAla: 6.707 ± 0.749
1.059SerCys: 1.059 ± 0.629
3.53SerAsp: 3.53 ± 0.007
3.883SerGlu: 3.883 ± 0.849
4.236SerPhe: 4.236 ± 0.412
4.589SerGly: 4.589 ± 0.622
1.412SerHis: 1.412 ± 0.739
3.883SerIle: 3.883 ± 0.729
2.471SerLys: 2.471 ± 0.416
7.766SerLeu: 7.766 ± 0.406
3.177SerMet: 3.177 ± 0.742
2.824SerAsn: 2.824 ± 0.952
4.589SerPro: 4.589 ± 0.622
2.471SerGln: 2.471 ± 0.11
3.53SerArg: 3.53 ± 0.519
5.295SerSer: 5.295 ± 1.041
4.589SerThr: 4.589 ± 0.956
3.177SerVal: 3.177 ± 0.217
0.706SerTrp: 0.706 ± 0.107
3.177SerTyr: 3.177 ± 1.794
0.0SerXaa: 0.0 ± 0.0
Thr
1.765ThrAla: 1.765 ± 1.055
1.412ThrCys: 1.412 ± 0.213
1.765ThrAsp: 1.765 ± 1.055
2.471ThrGlu: 2.471 ± 0.636
2.824ThrPhe: 2.824 ± 0.952
2.118ThrGly: 2.118 ± 0.32
0.706ThrHis: 0.706 ± 0.419
2.118ThrIle: 2.118 ± 1.371
2.471ThrLys: 2.471 ± 0.942
6.354ThrLeu: 6.354 ± 0.093
1.765ThrMet: 1.765 ± 1.048
6.001ThrAsn: 6.001 ± 0.643
6.001ThrPro: 6.001 ± 1.694
2.118ThrGln: 2.118 ± 0.32
1.059ThrArg: 1.059 ± 0.629
3.53ThrSer: 3.53 ± 1.059
3.53ThrThr: 3.53 ± 0.007
5.295ThrVal: 5.295 ± 0.536
1.059ThrTrp: 1.059 ± 0.423
2.471ThrTyr: 2.471 ± 0.11
0.0ThrXaa: 0.0 ± 0.0
Val
6.354ValAla: 6.354 ± 0.959
2.118ValCys: 2.118 ± 0.206
2.824ValAsp: 2.824 ± 0.1
4.236ValGlu: 4.236 ± 1.165
3.177ValPhe: 3.177 ± 0.835
6.001ValGly: 6.001 ± 0.935
0.706ValHis: 0.706 ± 0.107
4.236ValIle: 4.236 ± 1.464
7.06ValLys: 7.06 ± 2.09
5.648ValLeu: 5.648 ± 2.829
0.706ValMet: 0.706 ± 0.419
2.824ValAsn: 2.824 ± 0.426
4.942ValPro: 4.942 ± 2.323
2.471ValGln: 2.471 ± 1.162
4.236ValArg: 4.236 ± 0.113
4.942ValSer: 4.942 ± 0.746
5.648ValThr: 5.648 ± 0.852
6.707ValVal: 6.707 ± 0.302
1.765ValTrp: 1.765 ± 0.522
1.765ValTyr: 1.765 ± 0.529
0.0ValXaa: 0.0 ± 0.0
Trp
0.706TrpAla: 0.706 ± 0.107
0.706TrpCys: 0.706 ± 0.419
1.412TrpAsp: 1.412 ± 0.213
0.706TrpGlu: 0.706 ± 0.419
0.706TrpPhe: 0.706 ± 0.107
0.353TrpGly: 0.353 ± 0.316
0.353TrpHis: 0.353 ± 0.316
0.353TrpIle: 0.353 ± 0.316
0.706TrpLys: 0.706 ± 0.107
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.706TrpAsn: 0.706 ± 0.107
0.706TrpPro: 0.706 ± 0.107
0.706TrpGln: 0.706 ± 0.107
1.412TrpArg: 1.412 ± 0.313
1.059TrpSer: 1.059 ± 0.423
0.706TrpThr: 0.706 ± 0.632
1.765TrpVal: 1.765 ± 0.003
0.353TrpTrp: 0.353 ± 0.21
0.353TrpTyr: 0.353 ± 0.316
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.471TyrAla: 2.471 ± 0.11
0.353TyrCys: 0.353 ± 0.21
3.883TyrAsp: 3.883 ± 1.255
1.412TyrGlu: 1.412 ± 0.313
1.765TyrPhe: 1.765 ± 0.529
2.118TyrGly: 2.118 ± 1.371
1.059TyrHis: 1.059 ± 0.423
1.412TyrIle: 1.412 ± 0.213
1.412TyrLys: 1.412 ± 0.839
4.236TyrLeu: 4.236 ± 0.938
0.353TyrMet: 0.353 ± 0.21
0.353TyrAsn: 0.353 ± 0.316
2.471TyrPro: 2.471 ± 0.636
0.706TyrGln: 0.706 ± 0.632
1.765TyrArg: 1.765 ± 0.003
3.177TyrSer: 3.177 ± 1.268
1.765TyrThr: 1.765 ± 0.522
3.883TyrVal: 3.883 ± 0.323
1.412TyrTrp: 1.412 ± 0.313
1.059TyrTyr: 1.059 ± 0.949
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2834 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski