Amino acid dipepetide frequency for Wenzhou picorna-like virus 44

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.576AlaAla: 7.576 ± 0.0
1.684AlaCys: 1.684 ± 0.0
6.734AlaAsp: 6.734 ± 0.0
6.173AlaGlu: 6.173 ± 0.0
5.051AlaPhe: 5.051 ± 0.0
4.77AlaGly: 4.77 ± 0.0
0.281AlaHis: 0.281 ± 0.0
4.77AlaIle: 4.77 ± 0.0
4.489AlaLys: 4.489 ± 0.0
6.734AlaLeu: 6.734 ± 0.0
2.245AlaMet: 2.245 ± 0.0
5.612AlaAsn: 5.612 ± 0.0
3.086AlaPro: 3.086 ± 0.0
2.245AlaGln: 2.245 ± 0.0
4.489AlaArg: 4.489 ± 0.0
3.367AlaSer: 3.367 ± 0.0
4.209AlaThr: 4.209 ± 0.0
8.137AlaVal: 8.137 ± 0.0
1.964AlaTrp: 1.964 ± 0.0
2.806AlaTyr: 2.806 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.684CysAla: 1.684 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.842CysAsp: 0.842 ± 0.0
0.842CysGlu: 0.842 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.122CysGly: 1.122 ± 0.0
0.561CysHis: 0.561 ± 0.0
0.842CysIle: 0.842 ± 0.0
0.281CysLys: 0.281 ± 0.0
0.561CysLeu: 0.561 ± 0.0
0.281CysMet: 0.281 ± 0.0
1.122CysAsn: 1.122 ± 0.0
1.684CysPro: 1.684 ± 0.0
0.561CysGln: 0.561 ± 0.0
0.842CysArg: 0.842 ± 0.0
0.561CysSer: 0.561 ± 0.0
0.561CysThr: 0.561 ± 0.0
1.403CysVal: 1.403 ± 0.0
0.281CysTrp: 0.281 ± 0.0
0.281CysTyr: 0.281 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.734AspAla: 6.734 ± 0.0
0.842AspCys: 0.842 ± 0.0
3.086AspAsp: 3.086 ± 0.0
4.209AspGlu: 4.209 ± 0.0
2.525AspPhe: 2.525 ± 0.0
4.209AspGly: 4.209 ± 0.0
0.842AspHis: 0.842 ± 0.0
3.648AspIle: 3.648 ± 0.0
3.648AspLys: 3.648 ± 0.0
3.367AspLeu: 3.367 ± 0.0
1.684AspMet: 1.684 ± 0.0
2.245AspAsn: 2.245 ± 0.0
3.928AspPro: 3.928 ± 0.0
1.964AspGln: 1.964 ± 0.0
3.648AspArg: 3.648 ± 0.0
4.489AspSer: 4.489 ± 0.0
2.525AspThr: 2.525 ± 0.0
4.77AspVal: 4.77 ± 0.0
2.525AspTrp: 2.525 ± 0.0
1.403AspTyr: 1.403 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
6.173GluAla: 6.173 ± 0.0
1.122GluCys: 1.122 ± 0.0
3.928GluAsp: 3.928 ± 0.0
3.086GluGlu: 3.086 ± 0.0
3.086GluPhe: 3.086 ± 0.0
2.806GluGly: 2.806 ± 0.0
1.403GluHis: 1.403 ± 0.0
5.892GluIle: 5.892 ± 0.0
3.648GluLys: 3.648 ± 0.0
5.331GluLeu: 5.331 ± 0.0
1.122GluMet: 1.122 ± 0.0
1.684GluAsn: 1.684 ± 0.0
1.964GluPro: 1.964 ± 0.0
1.964GluGln: 1.964 ± 0.0
2.245GluArg: 2.245 ± 0.0
1.122GluSer: 1.122 ± 0.0
4.489GluThr: 4.489 ± 0.0
4.489GluVal: 4.489 ± 0.0
1.684GluTrp: 1.684 ± 0.0
2.525GluTyr: 2.525 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.245PheAla: 2.245 ± 0.0
0.561PheCys: 0.561 ± 0.0
3.086PheAsp: 3.086 ± 0.0
2.525PheGlu: 2.525 ± 0.0
1.684PhePhe: 1.684 ± 0.0
3.086PheGly: 3.086 ± 0.0
1.964PheHis: 1.964 ± 0.0
3.367PheIle: 3.367 ± 0.0
2.245PheLys: 2.245 ± 0.0
1.964PheLeu: 1.964 ± 0.0
1.403PheMet: 1.403 ± 0.0
1.403PheAsn: 1.403 ± 0.0
1.403PhePro: 1.403 ± 0.0
0.281PheGln: 0.281 ± 0.0
1.684PheArg: 1.684 ± 0.0
2.525PheSer: 2.525 ± 0.0
3.367PheThr: 3.367 ± 0.0
3.086PheVal: 3.086 ± 0.0
0.561PheTrp: 0.561 ± 0.0
1.122PheTyr: 1.122 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
7.015GlyAla: 7.015 ± 0.0
1.122GlyCys: 1.122 ± 0.0
4.489GlyAsp: 4.489 ± 0.0
3.648GlyGlu: 3.648 ± 0.0
3.367GlyPhe: 3.367 ± 0.0
3.648GlyGly: 3.648 ± 0.0
2.245GlyHis: 2.245 ± 0.0
4.489GlyIle: 4.489 ± 0.0
4.489GlyLys: 4.489 ± 0.0
4.489GlyLeu: 4.489 ± 0.0
0.561GlyMet: 0.561 ± 0.0
3.367GlyAsn: 3.367 ± 0.0
1.684GlyPro: 1.684 ± 0.0
1.964GlyGln: 1.964 ± 0.0
1.684GlyArg: 1.684 ± 0.0
3.648GlySer: 3.648 ± 0.0
3.928GlyThr: 3.928 ± 0.0
5.051GlyVal: 5.051 ± 0.0
0.842GlyTrp: 0.842 ± 0.0
1.403GlyTyr: 1.403 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.245HisAla: 2.245 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.842HisAsp: 0.842 ± 0.0
0.842HisGlu: 0.842 ± 0.0
0.842HisPhe: 0.842 ± 0.0
1.403HisGly: 1.403 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.842HisIle: 0.842 ± 0.0
0.281HisLys: 0.281 ± 0.0
1.684HisLeu: 1.684 ± 0.0
0.281HisMet: 0.281 ± 0.0
0.281HisAsn: 0.281 ± 0.0
1.684HisPro: 1.684 ± 0.0
0.842HisGln: 0.842 ± 0.0
1.684HisArg: 1.684 ± 0.0
1.684HisSer: 1.684 ± 0.0
2.525HisThr: 2.525 ± 0.0
3.648HisVal: 3.648 ± 0.0
0.281HisTrp: 0.281 ± 0.0
1.684HisTyr: 1.684 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
7.015IleAla: 7.015 ± 0.0
0.842IleCys: 0.842 ± 0.0
3.086IleAsp: 3.086 ± 0.0
2.245IleGlu: 2.245 ± 0.0
1.403IlePhe: 1.403 ± 0.0
2.525IleGly: 2.525 ± 0.0
0.842IleHis: 0.842 ± 0.0
2.806IleIle: 2.806 ± 0.0
2.806IleLys: 2.806 ± 0.0
4.489IleLeu: 4.489 ± 0.0
0.561IleMet: 0.561 ± 0.0
3.086IleAsn: 3.086 ± 0.0
5.331IlePro: 5.331 ± 0.0
0.842IleGln: 0.842 ± 0.0
1.122IleArg: 1.122 ± 0.0
5.612IleSer: 5.612 ± 0.0
4.209IleThr: 4.209 ± 0.0
4.77IleVal: 4.77 ± 0.0
0.281IleTrp: 0.281 ± 0.0
2.525IleTyr: 2.525 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
3.648LysAla: 3.648 ± 0.0
0.561LysCys: 0.561 ± 0.0
3.086LysAsp: 3.086 ± 0.0
2.806LysGlu: 2.806 ± 0.0
4.77LysPhe: 4.77 ± 0.0
2.806LysGly: 2.806 ± 0.0
0.561LysHis: 0.561 ± 0.0
2.806LysIle: 2.806 ± 0.0
2.245LysLys: 2.245 ± 0.0
6.734LysLeu: 6.734 ± 0.0
1.403LysMet: 1.403 ± 0.0
1.684LysAsn: 1.684 ± 0.0
1.122LysPro: 1.122 ± 0.0
1.964LysGln: 1.964 ± 0.0
3.086LysArg: 3.086 ± 0.0
5.612LysSer: 5.612 ± 0.0
1.684LysThr: 1.684 ± 0.0
3.648LysVal: 3.648 ± 0.0
0.842LysTrp: 0.842 ± 0.0
2.245LysTyr: 2.245 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
6.734LeuAla: 6.734 ± 0.0
1.122LeuCys: 1.122 ± 0.0
3.928LeuAsp: 3.928 ± 0.0
6.173LeuGlu: 6.173 ± 0.0
2.245LeuPhe: 2.245 ± 0.0
4.209LeuGly: 4.209 ± 0.0
2.245LeuHis: 2.245 ± 0.0
4.209LeuIle: 4.209 ± 0.0
4.77LeuLys: 4.77 ± 0.0
5.892LeuLeu: 5.892 ± 0.0
1.964LeuMet: 1.964 ± 0.0
3.648LeuAsn: 3.648 ± 0.0
4.209LeuPro: 4.209 ± 0.0
1.684LeuGln: 1.684 ± 0.0
7.576LeuArg: 7.576 ± 0.0
4.77LeuSer: 4.77 ± 0.0
4.77LeuThr: 4.77 ± 0.0
5.892LeuVal: 5.892 ± 0.0
1.684LeuTrp: 1.684 ± 0.0
2.806LeuTyr: 2.806 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.525MetAla: 2.525 ± 0.0
1.122MetCys: 1.122 ± 0.0
1.403MetAsp: 1.403 ± 0.0
1.403MetGlu: 1.403 ± 0.0
0.281MetPhe: 0.281 ± 0.0
2.245MetGly: 2.245 ± 0.0
0.842MetHis: 0.842 ± 0.0
0.842MetIle: 0.842 ± 0.0
0.561MetLys: 0.561 ± 0.0
1.403MetLeu: 1.403 ± 0.0
0.842MetMet: 0.842 ± 0.0
1.122MetAsn: 1.122 ± 0.0
1.122MetPro: 1.122 ± 0.0
0.561MetGln: 0.561 ± 0.0
1.403MetArg: 1.403 ± 0.0
0.842MetSer: 0.842 ± 0.0
0.842MetThr: 0.842 ± 0.0
1.122MetVal: 1.122 ± 0.0
1.122MetTrp: 1.122 ± 0.0
1.403MetTyr: 1.403 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.367AsnAla: 3.367 ± 0.0
0.0AsnCys: 0.0 ± 0.0
2.245AsnAsp: 2.245 ± 0.0
3.367AsnGlu: 3.367 ± 0.0
1.122AsnPhe: 1.122 ± 0.0
3.648AsnGly: 3.648 ± 0.0
1.684AsnHis: 1.684 ± 0.0
1.403AsnIle: 1.403 ± 0.0
1.964AsnLys: 1.964 ± 0.0
3.367AsnLeu: 3.367 ± 0.0
1.122AsnMet: 1.122 ± 0.0
1.964AsnAsn: 1.964 ± 0.0
3.928AsnPro: 3.928 ± 0.0
1.403AsnGln: 1.403 ± 0.0
1.122AsnArg: 1.122 ± 0.0
1.684AsnSer: 1.684 ± 0.0
4.209AsnThr: 4.209 ± 0.0
3.086AsnVal: 3.086 ± 0.0
0.561AsnTrp: 0.561 ± 0.0
0.561AsnTyr: 0.561 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.209ProAla: 4.209 ± 0.0
0.842ProCys: 0.842 ± 0.0
2.806ProAsp: 2.806 ± 0.0
3.367ProGlu: 3.367 ± 0.0
1.122ProPhe: 1.122 ± 0.0
3.928ProGly: 3.928 ± 0.0
1.684ProHis: 1.684 ± 0.0
2.806ProIle: 2.806 ± 0.0
4.209ProLys: 4.209 ± 0.0
5.331ProLeu: 5.331 ± 0.0
0.842ProMet: 0.842 ± 0.0
2.245ProAsn: 2.245 ± 0.0
3.648ProPro: 3.648 ± 0.0
1.684ProGln: 1.684 ± 0.0
2.245ProArg: 2.245 ± 0.0
2.525ProSer: 2.525 ± 0.0
5.331ProThr: 5.331 ± 0.0
3.928ProVal: 3.928 ± 0.0
0.842ProTrp: 0.842 ± 0.0
2.245ProTyr: 2.245 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
1.403GlnAla: 1.403 ± 0.0
0.561GlnCys: 0.561 ± 0.0
1.964GlnAsp: 1.964 ± 0.0
1.684GlnGlu: 1.684 ± 0.0
1.403GlnPhe: 1.403 ± 0.0
1.403GlnGly: 1.403 ± 0.0
1.122GlnHis: 1.122 ± 0.0
1.964GlnIle: 1.964 ± 0.0
1.964GlnLys: 1.964 ± 0.0
2.525GlnLeu: 2.525 ± 0.0
0.0GlnMet: 0.0 ± 0.0
1.684GlnAsn: 1.684 ± 0.0
0.842GlnPro: 0.842 ± 0.0
1.684GlnGln: 1.684 ± 0.0
2.245GlnArg: 2.245 ± 0.0
2.245GlnSer: 2.245 ± 0.0
1.684GlnThr: 1.684 ± 0.0
1.403GlnVal: 1.403 ± 0.0
0.561GlnTrp: 0.561 ± 0.0
1.122GlnTyr: 1.122 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
4.489ArgAla: 4.489 ± 0.0
0.281ArgCys: 0.281 ± 0.0
3.367ArgAsp: 3.367 ± 0.0
2.806ArgGlu: 2.806 ± 0.0
2.525ArgPhe: 2.525 ± 0.0
2.806ArgGly: 2.806 ± 0.0
1.403ArgHis: 1.403 ± 0.0
1.964ArgIle: 1.964 ± 0.0
0.842ArgLys: 0.842 ± 0.0
6.453ArgLeu: 6.453 ± 0.0
2.245ArgMet: 2.245 ± 0.0
1.403ArgAsn: 1.403 ± 0.0
2.806ArgPro: 2.806 ± 0.0
1.964ArgGln: 1.964 ± 0.0
3.648ArgArg: 3.648 ± 0.0
2.806ArgSer: 2.806 ± 0.0
4.209ArgThr: 4.209 ± 0.0
4.77ArgVal: 4.77 ± 0.0
0.561ArgTrp: 0.561 ± 0.0
1.684ArgTyr: 1.684 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.612SerAla: 5.612 ± 0.0
1.122SerCys: 1.122 ± 0.0
5.892SerAsp: 5.892 ± 0.0
4.209SerGlu: 4.209 ± 0.0
0.842SerPhe: 0.842 ± 0.0
3.928SerGly: 3.928 ± 0.0
0.561SerHis: 0.561 ± 0.0
3.086SerIle: 3.086 ± 0.0
2.806SerLys: 2.806 ± 0.0
4.489SerLeu: 4.489 ± 0.0
0.842SerMet: 0.842 ± 0.0
1.964SerAsn: 1.964 ± 0.0
3.928SerPro: 3.928 ± 0.0
0.842SerGln: 0.842 ± 0.0
4.209SerArg: 4.209 ± 0.0
4.489SerSer: 4.489 ± 0.0
4.77SerThr: 4.77 ± 0.0
4.77SerVal: 4.77 ± 0.0
1.403SerTrp: 1.403 ± 0.0
1.964SerTyr: 1.964 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
6.453ThrAla: 6.453 ± 0.0
0.561ThrCys: 0.561 ± 0.0
3.648ThrAsp: 3.648 ± 0.0
2.245ThrGlu: 2.245 ± 0.0
3.367ThrPhe: 3.367 ± 0.0
4.77ThrGly: 4.77 ± 0.0
1.684ThrHis: 1.684 ± 0.0
3.367ThrIle: 3.367 ± 0.0
3.648ThrLys: 3.648 ± 0.0
5.892ThrLeu: 5.892 ± 0.0
1.964ThrMet: 1.964 ± 0.0
2.525ThrAsn: 2.525 ± 0.0
4.77ThrPro: 4.77 ± 0.0
1.964ThrGln: 1.964 ± 0.0
3.086ThrArg: 3.086 ± 0.0
4.209ThrSer: 4.209 ± 0.0
2.806ThrThr: 2.806 ± 0.0
3.648ThrVal: 3.648 ± 0.0
1.684ThrTrp: 1.684 ± 0.0
1.684ThrTyr: 1.684 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
3.367ValAla: 3.367 ± 0.0
0.561ValCys: 0.561 ± 0.0
5.612ValAsp: 5.612 ± 0.0
5.331ValGlu: 5.331 ± 0.0
2.525ValPhe: 2.525 ± 0.0
5.612ValGly: 5.612 ± 0.0
3.086ValHis: 3.086 ± 0.0
4.77ValIle: 4.77 ± 0.0
4.489ValLys: 4.489 ± 0.0
5.051ValLeu: 5.051 ± 0.0
1.122ValMet: 1.122 ± 0.0
3.367ValAsn: 3.367 ± 0.0
5.892ValPro: 5.892 ± 0.0
1.684ValGln: 1.684 ± 0.0
4.209ValArg: 4.209 ± 0.0
5.331ValSer: 5.331 ± 0.0
4.489ValThr: 4.489 ± 0.0
6.173ValVal: 6.173 ± 0.0
1.964ValTrp: 1.964 ± 0.0
2.525ValTyr: 2.525 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.842TrpAla: 0.842 ± 0.0
0.842TrpCys: 0.842 ± 0.0
0.561TrpAsp: 0.561 ± 0.0
0.842TrpGlu: 0.842 ± 0.0
0.561TrpPhe: 0.561 ± 0.0
1.122TrpGly: 1.122 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.122TrpIle: 1.122 ± 0.0
1.964TrpLys: 1.964 ± 0.0
2.245TrpLeu: 2.245 ± 0.0
0.281TrpMet: 0.281 ± 0.0
0.842TrpAsn: 0.842 ± 0.0
0.561TrpPro: 0.561 ± 0.0
0.842TrpGln: 0.842 ± 0.0
1.403TrpArg: 1.403 ± 0.0
2.525TrpSer: 2.525 ± 0.0
1.403TrpThr: 1.403 ± 0.0
1.403TrpVal: 1.403 ± 0.0
0.561TrpTrp: 0.561 ± 0.0
1.122TrpTyr: 1.122 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.086TyrAla: 3.086 ± 0.0
0.561TyrCys: 0.561 ± 0.0
1.684TyrAsp: 1.684 ± 0.0
1.964TyrGlu: 1.964 ± 0.0
0.842TyrPhe: 0.842 ± 0.0
3.086TyrGly: 3.086 ± 0.0
0.561TyrHis: 0.561 ± 0.0
1.403TyrIle: 1.403 ± 0.0
1.964TyrLys: 1.964 ± 0.0
2.525TyrLeu: 2.525 ± 0.0
1.964TyrMet: 1.964 ± 0.0
0.561TyrAsn: 0.561 ± 0.0
2.245TyrPro: 2.245 ± 0.0
2.525TyrGln: 2.525 ± 0.0
1.403TyrArg: 1.403 ± 0.0
1.684TyrSer: 1.684 ± 0.0
2.245TyrThr: 2.245 ± 0.0
1.964TyrVal: 1.964 ± 0.0
0.842TyrTrp: 0.842 ± 0.0
0.561TyrTyr: 0.561 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3565 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski