Amino acid dipepetide frequency for Bergeyella zoohelcum ATCC 43767

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	3.905AlaAla: 3.905 ± 0.098	0.523AlaCys: 0.523 ± 0.031	3.196AlaAsp: 3.196 ± 0.083	4.673AlaGlu: 4.673 ± 0.092	3.427AlaPhe: 3.427 ± 0.066	4.203AlaGly: 4.203 ± 0.082	1.433AlaHis: 1.433 ± 0.042	5.032AlaIle: 5.032 ± 0.102	5.201AlaLys: 5.201 ± 0.089	6.447AlaLeu: 6.447 ± 0.107	1.842AlaMet: 1.842 ± 0.061	3.277AlaAsn: 3.277 ± 0.086	1.923AlaPro: 1.923 ± 0.051	3.069AlaGln: 3.069 ± 0.074	2.054AlaArg: 2.054 ± 0.066	3.848AlaSer: 3.848 ± 0.097	3.774AlaThr: 3.774 ± 0.088	4.253AlaVal: 4.253 ± 0.088	0.669AlaTrp: 0.669 ± 0.033	2.675AlaTyr: 2.675 ± 0.065	0.0AlaXaa: 0.0 ± 0.0
Cys	0.454CysAla: 0.454 ± 0.024	0.082CysCys: 0.082 ± 0.013	0.398CysAsp: 0.398 ± 0.024	0.432CysGlu: 0.432 ± 0.033	0.39CysPhe: 0.39 ± 0.025	0.593CysGly: 0.593 ± 0.032	0.158CysHis: 0.158 ± 0.019	0.599CysIle: 0.599 ± 0.033	0.454CysLys: 0.454 ± 0.028	0.63CysLeu: 0.63 ± 0.033	0.159CysMet: 0.159 ± 0.014	0.354CysAsn: 0.354 ± 0.025	0.346CysPro: 0.346 ± 0.028	0.228CysGln: 0.228 ± 0.019	0.259CysArg: 0.259 ± 0.018	0.5CysSer: 0.5 ± 0.028	0.484CysThr: 0.484 ± 0.027	0.427CysVal: 0.427 ± 0.026	0.07CysTrp: 0.07 ± 0.01	0.286CysTyr: 0.286 ± 0.021	0.0CysXaa: 0.0 ± 0.0
Asp	3.851AspAla: 3.851 ± 0.084	0.326AspCys: 0.326 ± 0.022	2.292AspAsp: 2.292 ± 0.058	4.081AspGlu: 4.081 ± 0.078	3.787AspPhe: 3.787 ± 0.081	3.144AspGly: 3.144 ± 0.089	0.722AspHis: 0.722 ± 0.028	4.139AspIle: 4.139 ± 0.09	3.985AspLys: 3.985 ± 0.093	4.42AspLeu: 4.42 ± 0.093	1.098AspMet: 1.098 ± 0.041	2.413AspAsn: 2.413 ± 0.059	1.355AspPro: 1.355 ± 0.045	1.191AspGln: 1.191 ± 0.047	1.847AspArg: 1.847 ± 0.058	2.359AspSer: 2.359 ± 0.067	2.611AspThr: 2.611 ± 0.06	3.111AspVal: 3.111 ± 0.069	0.664AspTrp: 0.664 ± 0.03	2.591AspTyr: 2.591 ± 0.067	0.0AspXaa: 0.0 ± 0.0
Glu	4.396GluAla: 4.396 ± 0.107	0.368GluCys: 0.368 ± 0.025	3.282GluAsp: 3.282 ± 0.08	5.706GluGlu: 5.706 ± 0.127	2.702GluPhe: 2.702 ± 0.068	3.933GluGly: 3.933 ± 0.086	1.26GluHis: 1.26 ± 0.044	6.267GluIle: 6.267 ± 0.101	7.792GluLys: 7.792 ± 0.13	5.762GluLeu: 5.762 ± 0.11	1.988GluMet: 1.988 ± 0.069	5.317GluAsn: 5.317 ± 0.096	1.412GluPro: 1.412 ± 0.047	2.876GluGln: 2.876 ± 0.074	2.794GluArg: 2.794 ± 0.064	2.925GluSer: 2.925 ± 0.071	3.434GluThr: 3.434 ± 0.078	4.551GluVal: 4.551 ± 0.093	0.697GluTrp: 0.697 ± 0.035	2.673GluTyr: 2.673 ± 0.071	0.0GluXaa: 0.0 ± 0.0
Phe	3.123PheAla: 3.123 ± 0.077	0.447PheCys: 0.447 ± 0.029	2.833PheAsp: 2.833 ± 0.072	3.101PheGlu: 3.101 ± 0.067	2.971PhePhe: 2.971 ± 0.09	3.683PheGly: 3.683 ± 0.074	1.099PheHis: 1.099 ± 0.043	4.063PheIle: 4.063 ± 0.102	3.081PheLys: 3.081 ± 0.07	4.825PheLeu: 4.825 ± 0.112	1.193PheMet: 1.193 ± 0.039	2.77PheAsn: 2.77 ± 0.09	1.93PhePro: 1.93 ± 0.051	2.002PheGln: 2.002 ± 0.055	1.948PheArg: 1.948 ± 0.061	4.273PheSer: 4.273 ± 0.094	2.922PheThr: 2.922 ± 0.08	3.434PheVal: 3.434 ± 0.08	0.605PheTrp: 0.605 ± 0.03	2.139PheTyr: 2.139 ± 0.066	0.0PheXaa: 0.0 ± 0.0
Gly	4.319GlyAla: 4.319 ± 0.091	0.542GlyCys: 0.542 ± 0.031	2.989GlyAsp: 2.989 ± 0.074	3.796GlyGlu: 3.796 ± 0.078	3.425GlyPhe: 3.425 ± 0.078	4.508GlyGly: 4.508 ± 0.105	1.121GlyHis: 1.121 ± 0.043	5.458GlyIle: 5.458 ± 0.097	5.899GlyLys: 5.899 ± 0.108	5.505GlyLeu: 5.505 ± 0.092	1.796GlyMet: 1.796 ± 0.055	4.026GlyAsn: 4.026 ± 0.117	1.044GlyPro: 1.044 ± 0.051	2.012GlyGln: 2.012 ± 0.056	2.121GlyArg: 2.121 ± 0.057	3.354GlySer: 3.354 ± 0.081	3.914GlyThr: 3.914 ± 0.102	4.505GlyVal: 4.505 ± 0.092	0.661GlyTrp: 0.661 ± 0.033	2.807GlyTyr: 2.807 ± 0.064	0.0GlyXaa: 0.0 ± 0.0
His	1.174HisAla: 1.174 ± 0.041	0.21HisCys: 0.21 ± 0.015	0.843HisAsp: 0.843 ± 0.036	1.056HisGlu: 1.056 ± 0.041	1.492HisPhe: 1.492 ± 0.043	1.172HisGly: 1.172 ± 0.049	0.749HisHis: 0.749 ± 0.042	1.658HisIle: 1.658 ± 0.05	1.253HisLys: 1.253 ± 0.046	2.265HisLeu: 2.265 ± 0.073	0.267HisMet: 0.267 ± 0.022	0.937HisAsn: 0.937 ± 0.039	1.06HisPro: 1.06 ± 0.038	1.028HisGln: 1.028 ± 0.04	0.904HisArg: 0.904 ± 0.037	1.358HisSer: 1.358 ± 0.046	1.148HisThr: 1.148 ± 0.048	0.713HisVal: 0.713 ± 0.034	0.24HisTrp: 0.24 ± 0.021	1.107HisTyr: 1.107 ± 0.039	0.0HisXaa: 0.0 ± 0.0
Ile	5.662IleAla: 5.662 ± 0.107	0.655IleCys: 0.655 ± 0.03	4.463IleAsp: 4.463 ± 0.079	5.461IleGlu: 5.461 ± 0.101	4.042IlePhe: 4.042 ± 0.099	5.217IleGly: 5.217 ± 0.099	1.969IleHis: 1.969 ± 0.058	6.152IleIle: 6.152 ± 0.124	5.496IleLys: 5.496 ± 0.097	6.989IleLeu: 6.989 ± 0.124	1.518IleMet: 1.518 ± 0.042	3.957IleAsn: 3.957 ± 0.093	3.318IlePro: 3.318 ± 0.067	3.256IleGln: 3.256 ± 0.074	2.831IleArg: 2.831 ± 0.069	5.81IleSer: 5.81 ± 0.105	4.584IleThr: 4.584 ± 0.088	4.529IleVal: 4.529 ± 0.086	0.651IleTrp: 0.651 ± 0.032	2.763IleTyr: 2.763 ± 0.064	0.0IleXaa: 0.0 ± 0.0
Lys	5.192LysAla: 5.192 ± 0.097	0.45LysCys: 0.45 ± 0.028	4.391LysAsp: 4.391 ± 0.092	6.622LysGlu: 6.622 ± 0.129	3.093LysPhe: 3.093 ± 0.075	4.727LysGly: 4.727 ± 0.09	1.419LysHis: 1.419 ± 0.049	7.344LysIle: 7.344 ± 0.121	8.083LysLys: 8.083 ± 0.132	6.129LysLeu: 6.129 ± 0.101	2.565LysMet: 2.565 ± 0.068	6.054LysAsn: 6.054 ± 0.098	2.316LysPro: 2.316 ± 0.058	2.776LysGln: 2.776 ± 0.07	2.921LysArg: 2.921 ± 0.068	4.565LysSer: 4.565 ± 0.095	4.629LysThr: 4.629 ± 0.082	4.945LysVal: 4.945 ± 0.076	0.763LysTrp: 0.763 ± 0.034	3.257LysTyr: 3.257 ± 0.079	0.0LysXaa: 0.0 ± 0.0
Leu	5.723LeuAla: 5.723 ± 0.089	0.757LeuCys: 0.757 ± 0.04	4.571LeuAsp: 4.571 ± 0.075	6.07LeuGlu: 6.07 ± 0.113	4.691LeuPhe: 4.691 ± 0.112	6.106LeuGly: 6.106 ± 0.116	1.89LeuHis: 1.89 ± 0.065	6.063LeuIle: 6.063 ± 0.098	7.52LeuLys: 7.52 ± 0.122	8.224LeuLeu: 8.224 ± 0.156	2.244LeuMet: 2.244 ± 0.064	4.831LeuAsn: 4.831 ± 0.109	3.723LeuPro: 3.723 ± 0.073	3.564LeuGln: 3.564 ± 0.077	3.32LeuArg: 3.32 ± 0.076	6.636LeuSer: 6.636 ± 0.097	4.492LeuThr: 4.492 ± 0.087	5.015LeuVal: 5.015 ± 0.092	0.877LeuTrp: 0.877 ± 0.036	3.251LeuTyr: 3.251 ± 0.078	0.0LeuXaa: 0.0 ± 0.0
Met	1.792MetAla: 1.792 ± 0.061	0.127MetCys: 0.127 ± 0.012	1.269MetAsp: 1.269 ± 0.044	1.762MetGlu: 1.762 ± 0.049	0.919MetPhe: 0.919 ± 0.046	1.734MetGly: 1.734 ± 0.056	0.404MetHis: 0.404 ± 0.026	1.762MetIle: 1.762 ± 0.055	2.739MetLys: 2.739 ± 0.064	2.119MetLeu: 2.119 ± 0.063	0.833MetMet: 0.833 ± 0.042	1.652MetAsn: 1.652 ± 0.06	0.952MetPro: 0.952 ± 0.036	0.816MetGln: 0.816 ± 0.035	0.953MetArg: 0.953 ± 0.037	1.419MetSer: 1.419 ± 0.046	1.279MetThr: 1.279 ± 0.048	1.616MetVal: 1.616 ± 0.05	0.18MetTrp: 0.18 ± 0.015	0.779MetTyr: 0.779 ± 0.032	0.0MetXaa: 0.0 ± 0.0
Asn	4.209AsnAla: 4.209 ± 0.088	0.335AsnCys: 0.335 ± 0.026	2.679AsnAsp: 2.679 ± 0.071	3.747AsnGlu: 3.747 ± 0.084	3.245AsnPhe: 3.245 ± 0.082	3.906AsnGly: 3.906 ± 0.106	1.407AsnHis: 1.407 ± 0.047	5.129AsnIle: 5.129 ± 0.115	4.119AsnLys: 4.119 ± 0.093	4.962AsnLeu: 4.962 ± 0.082	1.202AsnMet: 1.202 ± 0.046	3.251AsnAsn: 3.251 ± 0.096	2.697AsnPro: 2.697 ± 0.06	2.325AsnGln: 2.325 ± 0.062	2.082AsnArg: 2.082 ± 0.055	3.23AsnSer: 3.23 ± 0.089	3.607AsnThr: 3.607 ± 0.087	3.05AsnVal: 3.05 ± 0.077	0.669AsnTrp: 0.669 ± 0.029	2.585AsnTyr: 2.585 ± 0.064	0.0AsnXaa: 0.0 ± 0.0
Pro	1.93ProAla: 1.93 ± 0.06	0.232ProCys: 0.232 ± 0.023	1.613ProAsp: 1.613 ± 0.052	2.828ProGlu: 2.828 ± 0.07	1.835ProPhe: 1.835 ± 0.053	1.497ProGly: 1.497 ± 0.041	0.77ProHis: 0.77 ± 0.031	2.652ProIle: 2.652 ± 0.062	2.846ProLys: 2.846 ± 0.07	2.824ProLeu: 2.824 ± 0.057	0.885ProMet: 0.885 ± 0.04	2.24ProAsn: 2.24 ± 0.066	0.846ProPro: 0.846 ± 0.043	1.372ProGln: 1.372 ± 0.046	1.011ProArg: 1.011 ± 0.042	2.27ProSer: 2.27 ± 0.065	2.131ProThr: 2.131 ± 0.063	2.253ProVal: 2.253 ± 0.062	0.325ProTrp: 0.325 ± 0.024	1.527ProTyr: 1.527 ± 0.048	0.0ProXaa: 0.0 ± 0.0
Gln	2.131GlnAla: 2.131 ± 0.062	0.217GlnCys: 0.217 ± 0.017	1.704GlnAsp: 1.704 ± 0.055	2.696GlnGlu: 2.696 ± 0.064	1.787GlnPhe: 1.787 ± 0.05	2.297GlnGly: 2.297 ± 0.062	0.706GlnHis: 0.706 ± 0.031	2.868GlnIle: 2.868 ± 0.066	3.96GlnLys: 3.96 ± 0.08	3.822GlnLeu: 3.822 ± 0.079	1.095GlnMet: 1.095 ± 0.044	2.672GlnAsn: 2.672 ± 0.064	1.247GlnPro: 1.247 ± 0.044	1.683GlnGln: 1.683 ± 0.047	1.541GlnArg: 1.541 ± 0.051	2.197GlnSer: 2.197 ± 0.058	1.836GlnThr: 1.836 ± 0.048	2.002GlnVal: 2.002 ± 0.053	0.493GlnTrp: 0.493 ± 0.03	1.722GlnTyr: 1.722 ± 0.054	0.0GlnXaa: 0.0 ± 0.0
Arg	2.241ArgAla: 2.241 ± 0.06	0.201ArgCys: 0.201 ± 0.017	1.675ArgAsp: 1.675 ± 0.055	2.526ArgGlu: 2.526 ± 0.071	1.927ArgPhe: 1.927 ± 0.059	2.054ArgGly: 2.054 ± 0.065	0.634ArgHis: 0.634 ± 0.026	2.906ArgIle: 2.906 ± 0.058	3.476ArgLys: 3.476 ± 0.073	3.269ArgLeu: 3.269 ± 0.066	1.102ArgMet: 1.102 ± 0.037	2.411ArgAsn: 2.411 ± 0.058	1.136ArgPro: 1.136 ± 0.042	1.194ArgGln: 1.194 ± 0.039	1.387ArgArg: 1.387 ± 0.047	1.722ArgSer: 1.722 ± 0.054	1.772ArgThr: 1.772 ± 0.05	2.207ArgVal: 2.207 ± 0.067	0.381ArgTrp: 0.381 ± 0.024	1.558ArgTyr: 1.558 ± 0.058	0.0ArgXaa: 0.0 ± 0.0
Ser	3.942SerAla: 3.942 ± 0.1	0.581SerCys: 0.581 ± 0.031	2.968SerAsp: 2.968 ± 0.064	4.276SerGlu: 4.276 ± 0.097	3.668SerPhe: 3.668 ± 0.076	4.163SerGly: 4.163 ± 0.089	1.113SerHis: 1.113 ± 0.044	4.806SerIle: 4.806 ± 0.091	4.243SerLys: 4.243 ± 0.076	5.525SerLeu: 5.525 ± 0.088	1.36SerMet: 1.36 ± 0.057	3.081SerAsn: 3.081 ± 0.082	2.25SerPro: 2.25 ± 0.051	2.201SerGln: 2.201 ± 0.065	1.877SerArg: 1.877 ± 0.055	3.848SerSer: 3.848 ± 0.086	3.348SerThr: 3.348 ± 0.085	4.221SerVal: 4.221 ± 0.078	0.643SerTrp: 0.643 ± 0.033	2.423SerTyr: 2.423 ± 0.065	0.0SerXaa: 0.0 ± 0.0
Thr	3.834ThrAla: 3.834 ± 0.085	0.329ThrCys: 0.329 ± 0.02	2.974ThrAsp: 2.974 ± 0.068	3.851ThrGlu: 3.851 ± 0.086	2.51ThrPhe: 2.51 ± 0.069	3.673ThrGly: 3.673 ± 0.094	1.336ThrHis: 1.336 ± 0.046	4.444ThrIle: 4.444 ± 0.094	3.537ThrLys: 3.537 ± 0.072	5.348ThrLeu: 5.348 ± 0.091	1.244ThrMet: 1.244 ± 0.046	2.792ThrAsn: 2.792 ± 0.082	2.641ThrPro: 2.641 ± 0.077	2.384ThrGln: 2.384 ± 0.068	1.675ThrArg: 1.675 ± 0.056	3.247ThrSer: 3.247 ± 0.08	3.163ThrThr: 3.163 ± 0.085	3.419ThrVal: 3.419 ± 0.092	0.481ThrTrp: 0.481 ± 0.026	2.063ThrTyr: 2.063 ± 0.061	0.0ThrXaa: 0.0 ± 0.0
Val	4.143ValAla: 4.143 ± 0.084	0.496ValCys: 0.496 ± 0.029	3.11ValAsp: 3.11 ± 0.066	4.347ValGlu: 4.347 ± 0.082	3.372ValPhe: 3.372 ± 0.074	3.954ValGly: 3.954 ± 0.081	1.141ValHis: 1.141 ± 0.041	4.413ValIle: 4.413 ± 0.098	4.712ValLys: 4.712 ± 0.09	5.728ValLeu: 5.728 ± 0.109	1.577ValMet: 1.577 ± 0.048	3.422ValAsn: 3.422 ± 0.074	2.061ValPro: 2.061 ± 0.055	2.192ValGln: 2.192 ± 0.057	2.113ValArg: 2.113 ± 0.061	3.874ValSer: 3.874 ± 0.092	3.035ValThr: 3.035 ± 0.079	4.009ValVal: 4.009 ± 0.112	0.517ValTrp: 0.517 ± 0.03	2.371ValTyr: 2.371 ± 0.059	0.0ValXaa: 0.0 ± 0.0
Trp	0.697TrpAla: 0.697 ± 0.034	0.097TrpCys: 0.097 ± 0.012	0.567TrpAsp: 0.567 ± 0.032	0.693TrpGlu: 0.693 ± 0.034	0.518TrpPhe: 0.518 ± 0.029	0.597TrpGly: 0.597 ± 0.036	0.209TrpHis: 0.209 ± 0.019	0.698TrpIle: 0.698 ± 0.033	0.95TrpLys: 0.95 ± 0.038	0.883TrpLeu: 0.883 ± 0.036	0.343TrpMet: 0.343 ± 0.022	0.707TrpAsn: 0.707 ± 0.034	0.13TrpPro: 0.13 ± 0.016	0.456TrpGln: 0.456 ± 0.026	0.374TrpArg: 0.374 ± 0.026	0.49TrpSer: 0.49 ± 0.029	0.5TrpThr: 0.5 ± 0.029	0.728TrpVal: 0.728 ± 0.04	0.113TrpTrp: 0.113 ± 0.013	0.42TrpTyr: 0.42 ± 0.026	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.706TyrAla: 2.706 ± 0.06	0.329TyrCys: 0.329 ± 0.024	2.171TyrAsp: 2.171 ± 0.064	2.413TyrGlu: 2.413 ± 0.064	2.639TyrPhe: 2.639 ± 0.067	2.644TyrGly: 2.644 ± 0.067	1.093TyrHis: 1.093 ± 0.046	2.87TyrIle: 2.87 ± 0.071	2.891TyrLys: 2.891 ± 0.069	3.892TyrLeu: 3.892 ± 0.082	0.794TyrMet: 0.794 ± 0.034	2.274TyrAsn: 2.274 ± 0.069	1.5TyrPro: 1.5 ± 0.047	2.049TyrGln: 2.049 ± 0.062	1.769TyrArg: 1.769 ± 0.054	2.612TyrSer: 2.612 ± 0.077	2.28TyrThr: 2.28 ± 0.07	1.598TyrVal: 1.598 ± 0.057	0.472TyrTrp: 0.472 ± 0.028	2.014TyrTyr: 2.014 ± 0.059	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2120 proteins (671449 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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