Amino acid dipepetide frequency for Prunus dulcis (Almond) (Amygdalus dulcis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.105AlaAla: 6.105 ± 0.037	1.281AlaCys: 1.281 ± 0.011	3.096AlaAsp: 3.096 ± 0.016	4.219AlaGlu: 4.219 ± 0.024	2.83AlaPhe: 2.83 ± 0.018	4.049AlaGly: 4.049 ± 0.02	1.391AlaHis: 1.391 ± 0.012	3.67AlaIle: 3.67 ± 0.018	3.959AlaLys: 3.959 ± 0.019	6.702AlaLeu: 6.702 ± 0.025	1.734AlaMet: 1.734 ± 0.013	2.59AlaAsn: 2.59 ± 0.016	2.825AlaPro: 2.825 ± 0.018	2.242AlaGln: 2.242 ± 0.013	3.358AlaArg: 3.358 ± 0.02	5.979AlaSer: 5.979 ± 0.025	3.532AlaThr: 3.532 ± 0.016	4.695AlaVal: 4.695 ± 0.024	0.78AlaTrp: 0.78 ± 0.008	1.817AlaTyr: 1.817 ± 0.012	0.001AlaXaa: 0.001 ± 0.0
Cys	1.007CysAla: 1.007 ± 0.008	0.505CysCys: 0.505 ± 0.007	0.875CysAsp: 0.875 ± 0.008	0.892CysGlu: 0.892 ± 0.008	0.91CysPhe: 0.91 ± 0.009	1.413CysGly: 1.413 ± 0.013	0.496CysHis: 0.496 ± 0.006	1.001CysIle: 1.001 ± 0.01	1.188CysLys: 1.188 ± 0.011	1.902CysLeu: 1.902 ± 0.013	0.461CysMet: 0.461 ± 0.005	0.862CysAsn: 0.862 ± 0.008	0.941CysPro: 0.941 ± 0.011	0.627CysGln: 0.627 ± 0.007	1.037CysArg: 1.037 ± 0.009	1.857CysSer: 1.857 ± 0.013	0.91CysThr: 0.91 ± 0.008	1.055CysVal: 1.055 ± 0.009	0.254CysTrp: 0.254 ± 0.004	0.519CysTyr: 0.519 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	3.402AspAla: 3.402 ± 0.018	0.974AspCys: 0.974 ± 0.009	3.673AspAsp: 3.673 ± 0.025	3.985AspGlu: 3.985 ± 0.021	2.366AspPhe: 2.366 ± 0.015	3.778AspGly: 3.778 ± 0.02	1.322AspHis: 1.322 ± 0.012	2.95AspIle: 2.95 ± 0.014	2.769AspLys: 2.769 ± 0.015	5.149AspLeu: 5.149 ± 0.023	1.333AspMet: 1.333 ± 0.011	2.022AspAsn: 2.022 ± 0.014	2.634AspPro: 2.634 ± 0.015	1.878AspGln: 1.878 ± 0.013	2.404AspArg: 2.404 ± 0.015	4.155AspSer: 4.155 ± 0.023	2.185AspThr: 2.185 ± 0.014	3.696AspVal: 3.696 ± 0.017	0.723AspTrp: 0.723 ± 0.007	1.554AspTyr: 1.554 ± 0.011	0.001AspXaa: 0.001 ± 0.0
Glu	4.901GluAla: 4.901 ± 0.024	0.903GluCys: 0.903 ± 0.008	3.995GluAsp: 3.995 ± 0.02	6.229GluGlu: 6.229 ± 0.035	2.377GluPhe: 2.377 ± 0.014	3.819GluGly: 3.819 ± 0.016	1.316GluHis: 1.316 ± 0.01	3.674GluIle: 3.674 ± 0.017	4.792GluLys: 4.792 ± 0.024	6.027GluLeu: 6.027 ± 0.026	1.735GluMet: 1.735 ± 0.012	3.072GluAsn: 3.072 ± 0.018	2.172GluPro: 2.172 ± 0.016	2.225GluGln: 2.225 ± 0.016	3.409GluArg: 3.409 ± 0.02	4.453GluSer: 4.453 ± 0.02	3.043GluThr: 3.043 ± 0.017	4.237GluVal: 4.237 ± 0.02	0.773GluTrp: 0.773 ± 0.009	1.628GluTyr: 1.628 ± 0.012	0.001GluXaa: 0.001 ± 0.0
Phe	2.444PheAla: 2.444 ± 0.013	0.914PheCys: 0.914 ± 0.009	2.366PheAsp: 2.366 ± 0.014	2.34PheGlu: 2.34 ± 0.013	1.92PhePhe: 1.92 ± 0.014	3.128PheGly: 3.128 ± 0.024	1.078PheHis: 1.078 ± 0.009	2.029PheIle: 2.029 ± 0.014	2.152PheLys: 2.152 ± 0.014	4.308PheLeu: 4.308 ± 0.02	0.97PheMet: 0.97 ± 0.009	1.775PheAsn: 1.775 ± 0.012	2.074PhePro: 2.074 ± 0.014	1.585PheGln: 1.585 ± 0.011	2.034PheArg: 2.034 ± 0.013	4.092PheSer: 4.092 ± 0.019	2.0PheThr: 2.0 ± 0.013	2.783PheVal: 2.783 ± 0.016	0.586PheTrp: 0.586 ± 0.007	1.264PheTyr: 1.264 ± 0.01	0.001PheXaa: 0.001 ± 0.0
Gly	3.847GlyAla: 3.847 ± 0.024	1.355GlyCys: 1.355 ± 0.012	3.375GlyAsp: 3.375 ± 0.018	3.581GlyGlu: 3.581 ± 0.018	3.231GlyPhe: 3.231 ± 0.018	5.444GlyGly: 5.444 ± 0.058	1.596GlyHis: 1.596 ± 0.011	3.579GlyIle: 3.579 ± 0.017	4.092GlyLys: 4.092 ± 0.021	6.093GlyLeu: 6.093 ± 0.023	1.553GlyMet: 1.553 ± 0.011	3.164GlyAsn: 3.164 ± 0.022	2.513GlyPro: 2.513 ± 0.015	2.168GlyGln: 2.168 ± 0.015	3.611GlyArg: 3.611 ± 0.019	6.1GlySer: 6.1 ± 0.031	3.229GlyThr: 3.229 ± 0.017	4.25GlyVal: 4.25 ± 0.018	0.902GlyTrp: 0.902 ± 0.009	2.07GlyTyr: 2.07 ± 0.016	0.001GlyXaa: 0.001 ± 0.0
His	1.462HisAla: 1.462 ± 0.011	0.528HisCys: 0.528 ± 0.007	1.227HisAsp: 1.227 ± 0.01	1.358HisGlu: 1.358 ± 0.009	1.086HisPhe: 1.086 ± 0.008	1.786HisGly: 1.786 ± 0.013	1.037HisHis: 1.037 ± 0.013	1.253HisIle: 1.253 ± 0.01	1.248HisLys: 1.248 ± 0.01	2.524HisLeu: 2.524 ± 0.014	0.578HisMet: 0.578 ± 0.007	1.036HisAsn: 1.036 ± 0.009	1.415HisPro: 1.415 ± 0.012	1.086HisGln: 1.086 ± 0.011	1.371HisArg: 1.371 ± 0.009	1.96HisSer: 1.96 ± 0.014	0.994HisThr: 0.994 ± 0.009	1.572HisVal: 1.572 ± 0.011	0.325HisTrp: 0.325 ± 0.005	0.718HisTyr: 0.718 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	3.466IleAla: 3.466 ± 0.016	1.066IleCys: 1.066 ± 0.008	2.808IleAsp: 2.808 ± 0.016	3.203IleGlu: 3.203 ± 0.018	2.236IlePhe: 2.236 ± 0.014	3.377IleGly: 3.377 ± 0.018	1.271IleHis: 1.271 ± 0.009	2.656IleIle: 2.656 ± 0.016	2.902IleLys: 2.902 ± 0.018	5.086IleLeu: 5.086 ± 0.021	1.104IleMet: 1.104 ± 0.01	2.141IleAsn: 2.141 ± 0.012	2.995IlePro: 2.995 ± 0.021	1.969IleGln: 1.969 ± 0.013	2.587IleArg: 2.587 ± 0.015	4.792IleSer: 4.792 ± 0.021	2.512IleThr: 2.512 ± 0.017	3.379IleVal: 3.379 ± 0.017	0.724IleTrp: 0.724 ± 0.008	1.479IleTyr: 1.479 ± 0.013	0.001IleXaa: 0.001 ± 0.0
Lys	4.142LysAla: 4.142 ± 0.019	0.997LysCys: 0.997 ± 0.01	3.321LysAsp: 3.321 ± 0.015	4.68LysGlu: 4.68 ± 0.026	2.228LysPhe: 2.228 ± 0.013	3.677LysGly: 3.677 ± 0.018	1.404LysHis: 1.404 ± 0.011	3.155LysIle: 3.155 ± 0.019	4.695LysLys: 4.695 ± 0.025	6.162LysLeu: 6.162 ± 0.027	1.515LysMet: 1.515 ± 0.011	2.732LysAsn: 2.732 ± 0.015	2.826LysPro: 2.826 ± 0.019	2.385LysGln: 2.385 ± 0.013	3.621LysArg: 3.621 ± 0.018	4.675LysSer: 4.675 ± 0.024	2.902LysThr: 2.902 ± 0.016	3.915LysVal: 3.915 ± 0.017	0.839LysTrp: 0.839 ± 0.008	1.634LysTyr: 1.634 ± 0.011	0.0LysXaa: 0.0 ± 0.0
Leu	6.47LeuAla: 6.47 ± 0.025	1.924LeuCys: 1.924 ± 0.014	5.232LeuAsp: 5.232 ± 0.022	6.505LeuGlu: 6.505 ± 0.032	3.778LeuPhe: 3.778 ± 0.021	5.978LeuGly: 5.978 ± 0.024	2.658LeuHis: 2.658 ± 0.017	4.59LeuIle: 4.59 ± 0.022	6.34LeuLys: 6.34 ± 0.024	9.901LeuLeu: 9.901 ± 0.04	2.084LeuMet: 2.084 ± 0.013	4.026LeuAsn: 4.026 ± 0.021	5.322LeuPro: 5.322 ± 0.025	4.437LeuGln: 4.437 ± 0.02	5.443LeuArg: 5.443 ± 0.025	8.812LeuSer: 8.812 ± 0.035	4.503LeuThr: 4.503 ± 0.024	6.486LeuVal: 6.486 ± 0.022	1.17LeuTrp: 1.17 ± 0.01	2.523LeuTyr: 2.523 ± 0.015	0.002LeuXaa: 0.002 ± 0.0
Met	2.122MetAla: 2.122 ± 0.012	0.345MetCys: 0.345 ± 0.006	1.4MetAsp: 1.4 ± 0.011	1.96MetGlu: 1.96 ± 0.012	0.785MetPhe: 0.785 ± 0.008	1.649MetGly: 1.649 ± 0.012	0.57MetHis: 0.57 ± 0.007	1.122MetIle: 1.122 ± 0.01	1.613MetLys: 1.613 ± 0.012	2.161MetLeu: 2.161 ± 0.011	0.663MetMet: 0.663 ± 0.008	0.998MetAsn: 0.998 ± 0.008	1.123MetPro: 1.123 ± 0.009	0.938MetGln: 0.938 ± 0.009	1.224MetArg: 1.224 ± 0.01	1.743MetSer: 1.743 ± 0.011	1.001MetThr: 1.001 ± 0.008	1.668MetVal: 1.668 ± 0.012	0.258MetTrp: 0.258 ± 0.005	0.572MetTyr: 0.572 ± 0.007	0.001MetXaa: 0.001 ± 0.0
Asn	2.655AsnAla: 2.655 ± 0.016	0.885AsnCys: 0.885 ± 0.008	2.104AsnAsp: 2.104 ± 0.013	2.496AsnGlu: 2.496 ± 0.012	1.972AsnPhe: 1.972 ± 0.012	3.248AsnGly: 3.248 ± 0.02	1.14AsnHis: 1.14 ± 0.009	2.458AsnIle: 2.458 ± 0.014	2.462AsnLys: 2.462 ± 0.014	4.818AsnLeu: 4.818 ± 0.029	1.124AsnMet: 1.124 ± 0.01	2.38AsnAsn: 2.38 ± 0.02	2.443AsnPro: 2.443 ± 0.017	1.772AsnGln: 1.772 ± 0.013	1.999AsnArg: 1.999 ± 0.012	3.985AsnSer: 3.985 ± 0.02	1.957AsnThr: 1.957 ± 0.013	2.813AsnVal: 2.813 ± 0.014	0.593AsnTrp: 0.593 ± 0.006	1.328AsnTyr: 1.328 ± 0.011	0.001AsnXaa: 0.001 ± 0.0
Pro	2.991ProAla: 2.991 ± 0.019	0.783ProCys: 0.783 ± 0.008	2.452ProAsp: 2.452 ± 0.014	3.158ProGlu: 3.158 ± 0.018	1.971ProPhe: 1.971 ± 0.014	2.694ProGly: 2.694 ± 0.018	1.175ProHis: 1.175 ± 0.01	2.393ProIle: 2.393 ± 0.013	2.947ProLys: 2.947 ± 0.019	4.329ProLeu: 4.329 ± 0.023	0.962ProMet: 0.962 ± 0.009	2.5ProAsn: 2.5 ± 0.018	3.968ProPro: 3.968 ± 0.055	1.942ProGln: 1.942 ± 0.015	2.352ProArg: 2.352 ± 0.015	5.283ProSer: 5.283 ± 0.027	2.725ProThr: 2.725 ± 0.018	3.032ProVal: 3.032 ± 0.02	0.587ProTrp: 0.587 ± 0.008	1.344ProTyr: 1.344 ± 0.012	0.001ProXaa: 0.001 ± 0.0
Gln	2.492GlnAla: 2.492 ± 0.014	0.59GlnCys: 0.59 ± 0.007	1.753GlnAsp: 1.753 ± 0.011	2.449GlnGlu: 2.449 ± 0.015	1.416GlnPhe: 1.416 ± 0.012	2.201GlnGly: 2.201 ± 0.015	0.987GlnHis: 0.987 ± 0.009	2.045GlnIle: 2.045 ± 0.013	2.421GlnLys: 2.421 ± 0.016	3.831GlnLeu: 3.831 ± 0.019	0.994GlnMet: 0.994 ± 0.01	1.877GlnAsn: 1.877 ± 0.012	1.871GlnPro: 1.871 ± 0.015	2.181GlnGln: 2.181 ± 0.034	2.145GlnArg: 2.145 ± 0.014	2.984GlnSer: 2.984 ± 0.017	1.82GlnThr: 1.82 ± 0.013	2.458GlnVal: 2.458 ± 0.013	0.493GlnTrp: 0.493 ± 0.006	0.941GlnTyr: 0.941 ± 0.01	0.001GlnXaa: 0.001 ± 0.0
Arg	3.225ArgAla: 3.225 ± 0.019	0.971ArgCys: 0.971 ± 0.01	2.654ArgAsp: 2.654 ± 0.018	3.329ArgGlu: 3.329 ± 0.019	2.179ArgPhe: 2.179 ± 0.011	3.209ArgGly: 3.209 ± 0.02	1.339ArgHis: 1.339 ± 0.012	2.732ArgIle: 2.732 ± 0.016	3.75ArgLys: 3.75 ± 0.018	5.123ArgLeu: 5.123 ± 0.023	1.287ArgMet: 1.287 ± 0.009	2.441ArgAsn: 2.441 ± 0.014	2.385ArgPro: 2.385 ± 0.014	1.85ArgGln: 1.85 ± 0.012	3.79ArgArg: 3.79 ± 0.021	4.277ArgSer: 4.277 ± 0.02	2.473ArgThr: 2.473 ± 0.013	3.321ArgVal: 3.321 ± 0.017	0.765ArgTrp: 0.765 ± 0.008	1.466ArgTyr: 1.466 ± 0.012	0.001ArgXaa: 0.001 ± 0.0
Ser	5.374SerAla: 5.374 ± 0.025	1.731SerCys: 1.731 ± 0.013	4.375SerAsp: 4.375 ± 0.021	4.787SerGlu: 4.787 ± 0.022	3.921SerPhe: 3.921 ± 0.018	5.972SerGly: 5.972 ± 0.03	2.087SerHis: 2.087 ± 0.013	4.416SerIle: 4.416 ± 0.02	5.007SerLys: 5.007 ± 0.022	8.823SerLeu: 8.823 ± 0.036	2.065SerMet: 2.065 ± 0.013	4.178SerAsn: 4.178 ± 0.022	4.545SerPro: 4.545 ± 0.036	3.184SerGln: 3.184 ± 0.019	4.411SerArg: 4.411 ± 0.021	11.039SerSer: 11.039 ± 0.052	4.753SerThr: 4.753 ± 0.022	5.259SerVal: 5.259 ± 0.02	1.184SerTrp: 1.184 ± 0.011	2.299SerTyr: 2.299 ± 0.014	0.002SerXaa: 0.002 ± 0.0
Thr	3.352ThrAla: 3.352 ± 0.019	0.918ThrCys: 0.918 ± 0.009	2.254ThrAsp: 2.254 ± 0.015	2.804ThrGlu: 2.804 ± 0.016	2.061ThrPhe: 2.061 ± 0.013	3.185ThrGly: 3.185 ± 0.017	1.077ThrHis: 1.077 ± 0.009	2.667ThrIle: 2.667 ± 0.014	2.731ThrLys: 2.731 ± 0.014	4.726ThrLeu: 4.726 ± 0.021	1.17ThrMet: 1.17 ± 0.009	2.142ThrAsn: 2.142 ± 0.013	2.557ThrPro: 2.557 ± 0.015	1.695ThrGln: 1.695 ± 0.014	2.386ThrArg: 2.386 ± 0.016	4.575ThrSer: 4.575 ± 0.023	3.06ThrThr: 3.06 ± 0.02	3.239ThrVal: 3.239 ± 0.016	0.669ThrTrp: 0.669 ± 0.008	1.383ThrTyr: 1.383 ± 0.012	0.001ThrXaa: 0.001 ± 0.0
Val	4.807ValAla: 4.807 ± 0.023	1.181ValCys: 1.181 ± 0.011	3.765ValAsp: 3.765 ± 0.018	4.449ValGlu: 4.449 ± 0.02	2.737ValPhe: 2.737 ± 0.016	4.273ValGly: 4.273 ± 0.021	1.58ValHis: 1.58 ± 0.012	3.27ValIle: 3.27 ± 0.018	3.893ValLys: 3.893 ± 0.019	6.445ValLeu: 6.445 ± 0.027	1.492ValMet: 1.492 ± 0.011	2.607ValAsn: 2.607 ± 0.015	3.243ValPro: 3.243 ± 0.017	2.384ValGln: 2.384 ± 0.016	3.135ValArg: 3.135 ± 0.014	5.444ValSer: 5.444 ± 0.022	3.115ValThr: 3.115 ± 0.016	5.011ValVal: 5.011 ± 0.025	0.769ValTrp: 0.769 ± 0.008	1.944ValTyr: 1.944 ± 0.013	0.0ValXaa: 0.0 ± 0.0
Trp	0.771TrpAla: 0.771 ± 0.009	0.237TrpCys: 0.237 ± 0.004	0.724TrpAsp: 0.724 ± 0.008	0.785TrpGlu: 0.785 ± 0.008	0.573TrpPhe: 0.573 ± 0.007	0.76TrpGly: 0.76 ± 0.009	0.312TrpHis: 0.312 ± 0.005	0.674TrpIle: 0.674 ± 0.008	0.992TrpLys: 0.992 ± 0.01	1.27TrpLeu: 1.27 ± 0.012	0.349TrpMet: 0.349 ± 0.006	0.717TrpAsn: 0.717 ± 0.008	0.499TrpPro: 0.499 ± 0.006	0.446TrpGln: 0.446 ± 0.006	0.823TrpArg: 0.823 ± 0.009	0.983TrpSer: 0.983 ± 0.009	0.651TrpThr: 0.651 ± 0.008	0.883TrpVal: 0.883 ± 0.008	0.249TrpTrp: 0.249 ± 0.005	0.335TrpTyr: 0.335 ± 0.006	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.821TyrAla: 1.821 ± 0.013	0.62TyrCys: 0.62 ± 0.007	1.501TyrAsp: 1.501 ± 0.011	1.572TyrGlu: 1.572 ± 0.01	1.267TyrPhe: 1.267 ± 0.012	2.113TyrGly: 2.113 ± 0.016	0.726TyrHis: 0.726 ± 0.008	1.422TyrIle: 1.422 ± 0.011	1.549TyrLys: 1.549 ± 0.011	2.805TyrLeu: 2.805 ± 0.017	0.741TyrMet: 0.741 ± 0.008	1.372TyrAsn: 1.372 ± 0.011	1.238TyrPro: 1.238 ± 0.011	0.954TyrGln: 0.954 ± 0.009	1.428TyrArg: 1.428 ± 0.01	2.224TyrSer: 2.224 ± 0.016	1.282TyrThr: 1.282 ± 0.011	1.791TyrVal: 1.791 ± 0.012	0.39TyrTrp: 0.39 ± 0.007	0.917TyrTyr: 0.917 ± 0.01	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.002XaaGly: 0.002 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.001XaaTrp: 0.001 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.049XaaXaa: 0.049 ± 0.02

Statistics based on 31934 proteins (13217611 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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