Amino acid dipepetide frequency for Gordonia araii NBRC 100433

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	20.0AlaAla: 20.0 ± 0.195	0.867AlaCys: 0.867 ± 0.03	9.251AlaAsp: 9.251 ± 0.109	7.766AlaGlu: 7.766 ± 0.084	3.425AlaPhe: 3.425 ± 0.054	11.693AlaGly: 11.693 ± 0.116	2.533AlaHis: 2.533 ± 0.05	5.569AlaIle: 5.569 ± 0.078	3.396AlaLys: 3.396 ± 0.071	12.591AlaLeu: 12.591 ± 0.127	2.852AlaMet: 2.852 ± 0.05	2.702AlaAsn: 2.702 ± 0.049	6.488AlaPro: 6.488 ± 0.09	4.029AlaGln: 4.029 ± 0.069	9.133AlaArg: 9.133 ± 0.098	6.36AlaSer: 6.36 ± 0.069	7.568AlaThr: 7.568 ± 0.085	11.612AlaVal: 11.612 ± 0.133	1.648AlaTrp: 1.648 ± 0.035	2.388AlaTyr: 2.388 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.995CysAla: 0.995 ± 0.03	0.082CysCys: 0.082 ± 0.008	0.421CysAsp: 0.421 ± 0.02	0.365CysGlu: 0.365 ± 0.016	0.204CysPhe: 0.204 ± 0.014	0.845CysGly: 0.845 ± 0.028	0.157CysHis: 0.157 ± 0.011	0.226CysIle: 0.226 ± 0.014	0.099CysLys: 0.099 ± 0.009	0.549CysLeu: 0.549 ± 0.02	0.122CysMet: 0.122 ± 0.011	0.163CysAsn: 0.163 ± 0.011	0.408CysPro: 0.408 ± 0.021	0.182CysGln: 0.182 ± 0.013	0.535CysArg: 0.535 ± 0.023	0.486CysSer: 0.486 ± 0.019	0.41CysThr: 0.41 ± 0.022	0.555CysVal: 0.555 ± 0.023	0.109CysTrp: 0.109 ± 0.012	0.172CysTyr: 0.172 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	8.19AspAla: 8.19 ± 0.091	0.393AspCys: 0.393 ± 0.017	5.345AspAsp: 5.345 ± 0.077	5.088AspGlu: 5.088 ± 0.077	1.9AspPhe: 1.9 ± 0.045	6.565AspGly: 6.565 ± 0.085	1.287AspHis: 1.287 ± 0.034	2.427AspIle: 2.427 ± 0.048	1.417AspLys: 1.417 ± 0.035	6.377AspLeu: 6.377 ± 0.083	0.96AspMet: 0.96 ± 0.027	1.188AspAsn: 1.188 ± 0.035	4.546AspPro: 4.546 ± 0.07	1.761AspGln: 1.761 ± 0.04	4.949AspArg: 4.949 ± 0.065	3.042AspSer: 3.042 ± 0.055	2.926AspThr: 2.926 ± 0.053	5.419AspVal: 5.419 ± 0.083	0.969AspTrp: 0.969 ± 0.032	1.408AspTyr: 1.408 ± 0.035	0.0AspXaa: 0.0 ± 0.0
Glu	6.323GluAla: 6.323 ± 0.079	0.341GluCys: 0.341 ± 0.018	2.353GluAsp: 2.353 ± 0.058	2.678GluGlu: 2.678 ± 0.054	1.94GluPhe: 1.94 ± 0.042	3.275GluGly: 3.275 ± 0.057	1.382GluHis: 1.382 ± 0.039	2.803GluIle: 2.803 ± 0.05	1.575GluLys: 1.575 ± 0.044	6.447GluLeu: 6.447 ± 0.088	1.176GluMet: 1.176 ± 0.029	1.23GluAsn: 1.23 ± 0.035	3.09GluPro: 3.09 ± 0.06	2.223GluGln: 2.223 ± 0.05	4.628GluArg: 4.628 ± 0.064	3.059GluSer: 3.059 ± 0.053	2.799GluThr: 2.799 ± 0.059	4.543GluVal: 4.543 ± 0.072	0.84GluTrp: 0.84 ± 0.027	1.173GluTyr: 1.173 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.271PheAla: 4.271 ± 0.069	0.242PheCys: 0.242 ± 0.014	2.553PheAsp: 2.553 ± 0.05	1.507PheGlu: 1.507 ± 0.038	0.989PhePhe: 0.989 ± 0.032	3.378PheGly: 3.378 ± 0.05	0.575PheHis: 0.575 ± 0.027	1.086PheIle: 1.086 ± 0.035	0.494PheLys: 0.494 ± 0.025	2.653PheLeu: 2.653 ± 0.052	0.438PheMet: 0.438 ± 0.019	0.678PheAsn: 0.678 ± 0.027	1.37PhePro: 1.37 ± 0.039	0.629PheGln: 0.629 ± 0.022	1.657PheArg: 1.657 ± 0.041	1.63PheSer: 1.63 ± 0.039	2.053PheThr: 2.053 ± 0.04	2.552PheVal: 2.552 ± 0.046	0.429PheTrp: 0.429 ± 0.02	0.691PheTyr: 0.691 ± 0.024	0.0PheXaa: 0.0 ± 0.0
Gly	10.299GlyAla: 10.299 ± 0.111	0.736GlyCys: 0.736 ± 0.027	5.411GlyAsp: 5.411 ± 0.066	4.962GlyGlu: 4.962 ± 0.075	3.111GlyPhe: 3.111 ± 0.054	7.736GlyGly: 7.736 ± 0.105	1.865GlyHis: 1.865 ± 0.042	4.226GlyIle: 4.226 ± 0.06	2.758GlyLys: 2.758 ± 0.063	8.4GlyLeu: 8.4 ± 0.079	2.069GlyMet: 2.069 ± 0.039	1.895GlyAsn: 1.895 ± 0.042	4.624GlyPro: 4.624 ± 0.066	2.801GlyGln: 2.801 ± 0.052	6.486GlyArg: 6.486 ± 0.081	5.342GlySer: 5.342 ± 0.069	5.274GlyThr: 5.274 ± 0.074	7.483GlyVal: 7.483 ± 0.073	1.546GlyTrp: 1.546 ± 0.037	2.304GlyTyr: 2.304 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	2.147HisAla: 2.147 ± 0.046	0.172HisCys: 0.172 ± 0.01	1.293HisAsp: 1.293 ± 0.036	0.987HisGlu: 0.987 ± 0.025	0.627HisPhe: 0.627 ± 0.025	1.95HisGly: 1.95 ± 0.04	0.591HisHis: 0.591 ± 0.025	0.723HisIle: 0.723 ± 0.024	0.331HisLys: 0.331 ± 0.017	2.004HisLeu: 2.004 ± 0.044	0.311HisMet: 0.311 ± 0.017	0.446HisAsn: 0.446 ± 0.019	1.487HisPro: 1.487 ± 0.036	0.543HisGln: 0.543 ± 0.021	1.885HisArg: 1.885 ± 0.044	1.037HisSer: 1.037 ± 0.029	1.009HisThr: 1.009 ± 0.029	1.586HisVal: 1.586 ± 0.041	0.303HisTrp: 0.303 ± 0.015	0.496HisTyr: 0.496 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	6.687IleAla: 6.687 ± 0.084	0.353IleCys: 0.353 ± 0.017	3.485IleAsp: 3.485 ± 0.056	2.511IleGlu: 2.511 ± 0.051	0.964IlePhe: 0.964 ± 0.031	4.658IleGly: 4.658 ± 0.064	0.76IleHis: 0.76 ± 0.023	1.585IleIle: 1.585 ± 0.044	0.909IleLys: 0.909 ± 0.033	3.263IleLeu: 3.263 ± 0.055	0.605IleMet: 0.605 ± 0.025	1.117IleAsn: 1.117 ± 0.029	2.441IlePro: 2.441 ± 0.05	0.8IleGln: 0.8 ± 0.026	2.702IleArg: 2.702 ± 0.05	2.249IleSer: 2.249 ± 0.044	2.771IleThr: 2.771 ± 0.054	4.282IleVal: 4.282 ± 0.064	0.441IleTrp: 0.441 ± 0.02	0.721IleTyr: 0.721 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	2.98LysAla: 2.98 ± 0.071	0.133LysCys: 0.133 ± 0.01	1.108LysAsp: 1.108 ± 0.038	1.016LysGlu: 1.016 ± 0.036	0.628LysPhe: 0.628 ± 0.025	1.751LysGly: 1.751 ± 0.051	0.478LysHis: 0.478 ± 0.02	1.128LysIle: 1.128 ± 0.031	0.914LysLys: 0.914 ± 0.044	2.363LysLeu: 2.363 ± 0.056	0.509LysMet: 0.509 ± 0.025	0.622LysAsn: 0.622 ± 0.025	1.572LysPro: 1.572 ± 0.044	0.765LysGln: 0.765 ± 0.026	1.881LysArg: 1.881 ± 0.048	1.332LysSer: 1.332 ± 0.038	1.539LysThr: 1.539 ± 0.043	2.114LysVal: 2.114 ± 0.05	0.341LysTrp: 0.341 ± 0.017	0.486LysTyr: 0.486 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	14.192LeuAla: 14.192 ± 0.131	0.679LeuCys: 0.679 ± 0.024	6.727LeuAsp: 6.727 ± 0.077	3.985LeuGlu: 3.985 ± 0.067	2.608LeuPhe: 2.608 ± 0.05	8.572LeuGly: 8.572 ± 0.09	1.771LeuHis: 1.771 ± 0.035	4.123LeuIle: 4.123 ± 0.064	1.778LeuLys: 1.778 ± 0.047	9.107LeuLeu: 9.107 ± 0.116	1.658LeuMet: 1.658 ± 0.041	1.881LeuAsn: 1.881 ± 0.041	5.539LeuPro: 5.539 ± 0.072	1.978LeuGln: 1.978 ± 0.041	7.518LeuArg: 7.518 ± 0.084	5.238LeuSer: 5.238 ± 0.066	6.163LeuThr: 6.163 ± 0.073	8.733LeuVal: 8.733 ± 0.102	1.142LeuTrp: 1.142 ± 0.037	1.608LeuTyr: 1.608 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	2.506MetAla: 2.506 ± 0.048	0.157MetCys: 0.157 ± 0.01	0.864MetAsp: 0.864 ± 0.029	0.691MetGlu: 0.691 ± 0.026	0.595MetPhe: 0.595 ± 0.026	1.527MetGly: 1.527 ± 0.036	0.361MetHis: 0.361 ± 0.018	0.945MetIle: 0.945 ± 0.028	0.492MetLys: 0.492 ± 0.025	1.922MetLeu: 1.922 ± 0.042	0.406MetMet: 0.406 ± 0.02	0.491MetAsn: 0.491 ± 0.021	1.187MetPro: 1.187 ± 0.035	0.457MetGln: 0.457 ± 0.02	1.604MetArg: 1.604 ± 0.039	1.639MetSer: 1.639 ± 0.037	1.8MetThr: 1.8 ± 0.04	1.597MetVal: 1.597 ± 0.037	0.268MetTrp: 0.268 ± 0.018	0.316MetTyr: 0.316 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.613AsnAla: 2.613 ± 0.053	0.147AsnCys: 0.147 ± 0.012	1.196AsnAsp: 1.196 ± 0.037	1.029AsnGlu: 1.029 ± 0.033	0.599AsnPhe: 0.599 ± 0.024	2.032AsnGly: 2.032 ± 0.044	0.451AsnHis: 0.451 ± 0.02	0.944AsnIle: 0.944 ± 0.027	0.532AsnLys: 0.532 ± 0.023	2.202AsnLeu: 2.202 ± 0.046	0.35AsnMet: 0.35 ± 0.018	0.56AsnAsn: 0.56 ± 0.023	1.835AsnPro: 1.835 ± 0.037	0.635AsnGln: 0.635 ± 0.025	1.69AsnArg: 1.69 ± 0.041	1.131AsnSer: 1.131 ± 0.03	1.244AsnThr: 1.244 ± 0.034	1.737AsnVal: 1.737 ± 0.039	0.347AsnTrp: 0.347 ± 0.018	0.511AsnTyr: 0.511 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	7.155ProAla: 7.155 ± 0.093	0.275ProCys: 0.275 ± 0.015	4.662ProAsp: 4.662 ± 0.063	3.653ProGlu: 3.653 ± 0.057	1.619ProPhe: 1.619 ± 0.031	5.745ProGly: 5.745 ± 0.082	1.059ProHis: 1.059 ± 0.03	2.253ProIle: 2.253 ± 0.046	1.417ProLys: 1.417 ± 0.042	4.58ProLeu: 4.58 ± 0.068	1.154ProMet: 1.154 ± 0.033	1.337ProAsn: 1.337 ± 0.042	3.162ProPro: 3.162 ± 0.073	1.611ProGln: 1.611 ± 0.042	3.728ProArg: 3.728 ± 0.056	3.378ProSer: 3.378 ± 0.056	3.458ProThr: 3.458 ± 0.061	5.054ProVal: 5.054 ± 0.064	0.834ProTrp: 0.834 ± 0.027	1.108ProTyr: 1.108 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.408GlnAla: 3.408 ± 0.057	0.167GlnCys: 0.167 ± 0.014	0.952GlnAsp: 0.952 ± 0.026	1.131GlnGlu: 1.131 ± 0.032	0.879GlnPhe: 0.879 ± 0.026	1.82GlnGly: 1.82 ± 0.049	0.58GlnHis: 0.58 ± 0.022	1.556GlnIle: 1.556 ± 0.038	0.576GlnLys: 0.576 ± 0.023	3.003GlnLeu: 3.003 ± 0.055	0.688GlnMet: 0.688 ± 0.024	0.615GlnAsn: 0.615 ± 0.024	1.718GlnPro: 1.718 ± 0.042	1.203GlnGln: 1.203 ± 0.045	2.728GlnArg: 2.728 ± 0.047	1.311GlnSer: 1.311 ± 0.033	1.517GlnThr: 1.517 ± 0.036	2.458GlnVal: 2.458 ± 0.042	0.521GlnTrp: 0.521 ± 0.022	0.598GlnTyr: 0.598 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	8.745ArgAla: 8.745 ± 0.082	0.527ArgCys: 0.527 ± 0.022	4.723ArgAsp: 4.723 ± 0.06	4.231ArgGlu: 4.231 ± 0.057	2.514ArgPhe: 2.514 ± 0.044	5.489ArgGly: 5.489 ± 0.068	1.695ArgHis: 1.695 ± 0.04	3.487ArgIle: 3.487 ± 0.052	1.767ArgLys: 1.767 ± 0.051	7.386ArgLeu: 7.386 ± 0.074	1.81ArgMet: 1.81 ± 0.036	1.662ArgAsn: 1.662 ± 0.037	4.1ArgPro: 4.1 ± 0.063	2.116ArgGln: 2.116 ± 0.052	6.884ArgArg: 6.884 ± 0.104	4.246ArgSer: 4.246 ± 0.059	4.301ArgThr: 4.301 ± 0.057	5.901ArgVal: 5.901 ± 0.08	1.406ArgTrp: 1.406 ± 0.034	1.924ArgTyr: 1.924 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	7.138SerAla: 7.138 ± 0.074	0.353SerCys: 0.353 ± 0.017	3.279SerAsp: 3.279 ± 0.059	2.593SerGlu: 2.593 ± 0.051	1.606SerPhe: 1.606 ± 0.041	5.852SerGly: 5.852 ± 0.07	0.967SerHis: 0.967 ± 0.03	2.339SerIle: 2.339 ± 0.051	1.291SerLys: 1.291 ± 0.032	4.784SerLeu: 4.784 ± 0.062	1.335SerMet: 1.335 ± 0.035	1.077SerAsn: 1.077 ± 0.027	3.265SerPro: 3.265 ± 0.052	1.36SerGln: 1.36 ± 0.033	3.914SerArg: 3.914 ± 0.058	3.356SerSer: 3.356 ± 0.06	3.708SerThr: 3.708 ± 0.05	4.732SerVal: 4.732 ± 0.064	0.858SerTrp: 0.858 ± 0.029	1.128SerTyr: 1.128 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	7.986ThrAla: 7.986 ± 0.088	0.387ThrCys: 0.387 ± 0.018	3.835ThrAsp: 3.835 ± 0.066	3.061ThrGlu: 3.061 ± 0.053	1.69ThrPhe: 1.69 ± 0.036	5.942ThrGly: 5.942 ± 0.067	1.07ThrHis: 1.07 ± 0.034	2.657ThrIle: 2.657 ± 0.05	1.44ThrLys: 1.44 ± 0.04	5.115ThrLeu: 5.115 ± 0.068	1.212ThrMet: 1.212 ± 0.031	1.223ThrAsn: 1.223 ± 0.033	3.772ThrPro: 3.772 ± 0.07	1.385ThrGln: 1.385 ± 0.035	3.823ThrArg: 3.823 ± 0.058	3.265ThrSer: 3.265 ± 0.053	3.922ThrThr: 3.922 ± 0.073	6.156ThrVal: 6.156 ± 0.073	0.854ThrTrp: 0.854 ± 0.027	1.232ThrTyr: 1.232 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	12.287ValAla: 12.287 ± 0.131	0.715ValCys: 0.715 ± 0.026	6.548ValAsp: 6.548 ± 0.084	4.869ValGlu: 4.869 ± 0.07	2.661ValPhe: 2.661 ± 0.048	7.528ValGly: 7.528 ± 0.087	1.644ValHis: 1.644 ± 0.04	3.877ValIle: 3.877 ± 0.062	1.776ValLys: 1.776 ± 0.048	8.415ValLeu: 8.415 ± 0.1	1.516ValMet: 1.516 ± 0.036	2.036ValAsn: 2.036 ± 0.048	4.752ValPro: 4.752 ± 0.059	1.756ValGln: 1.756 ± 0.039	5.918ValArg: 5.918 ± 0.071	4.676ValSer: 4.676 ± 0.057	5.541ValThr: 5.541 ± 0.084	9.032ValVal: 9.032 ± 0.118	1.068ValTrp: 1.068 ± 0.031	1.693ValTyr: 1.693 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.625TrpAla: 1.625 ± 0.036	0.147TrpCys: 0.147 ± 0.011	0.752TrpAsp: 0.752 ± 0.031	0.653TrpGlu: 0.653 ± 0.023	0.566TrpPhe: 0.566 ± 0.023	1.019TrpGly: 1.019 ± 0.027	0.318TrpHis: 0.318 ± 0.016	0.662TrpIle: 0.662 ± 0.026	0.326TrpLys: 0.326 ± 0.019	1.596TrpLeu: 1.596 ± 0.039	0.345TrpMet: 0.345 ± 0.017	0.381TrpAsn: 0.381 ± 0.019	0.758TrpPro: 0.758 ± 0.025	0.55TrpGln: 0.55 ± 0.021	1.295TrpArg: 1.295 ± 0.04	0.974TrpSer: 0.974 ± 0.03	0.874TrpThr: 0.874 ± 0.029	1.129TrpVal: 1.129 ± 0.031	0.375TrpTrp: 0.375 ± 0.02	0.32TrpTyr: 0.32 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.326TyrAla: 2.326 ± 0.052	0.212TyrCys: 0.212 ± 0.014	1.395TyrAsp: 1.395 ± 0.038	1.104TyrGlu: 1.104 ± 0.034	0.748TyrPhe: 0.748 ± 0.028	1.95TyrGly: 1.95 ± 0.049	0.385TyrHis: 0.385 ± 0.019	0.687TyrIle: 0.687 ± 0.023	0.375TyrLys: 0.375 ± 0.022	2.244TyrLeu: 2.244 ± 0.047	0.31TyrMet: 0.31 ± 0.017	0.48TyrAsn: 0.48 ± 0.021	1.127TyrPro: 1.127 ± 0.031	0.645TyrGln: 0.645 ± 0.023	1.959TyrArg: 1.959 ± 0.041	1.183TyrSer: 1.183 ± 0.032	1.149TyrThr: 1.149 ± 0.031	1.631TyrVal: 1.631 ± 0.046	0.367TyrTrp: 0.367 ± 0.016	0.503TyrTyr: 0.503 ± 0.021	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3796 proteins (1200781 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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