Amino acid dipepetide frequency for Morelia spilota papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.466AlaAla: 4.466 ± 1.507
0.0AlaCys: 0.0 ± 0.0
4.913AlaAsp: 4.913 ± 1.399
4.466AlaGlu: 4.466 ± 1.426
2.68AlaPhe: 2.68 ± 0.875
2.68AlaGly: 2.68 ± 1.132
0.0AlaHis: 0.0 ± 0.0
3.126AlaIle: 3.126 ± 0.952
4.466AlaLys: 4.466 ± 1.031
5.36AlaLeu: 5.36 ± 1.333
1.34AlaMet: 1.34 ± 0.72
1.787AlaAsn: 1.787 ± 1.071
3.126AlaPro: 3.126 ± 1.519
1.787AlaGln: 1.787 ± 0.267
8.039AlaArg: 8.039 ± 1.056
4.02AlaSer: 4.02 ± 0.879
3.573AlaThr: 3.573 ± 1.205
4.02AlaVal: 4.02 ± 0.925
0.893AlaTrp: 0.893 ± 0.692
2.233AlaTyr: 2.233 ± 0.777
0.0AlaXaa: 0.0 ± 0.0
Cys
0.447CysAla: 0.447 ± 0.508
0.447CysCys: 0.447 ± 0.346
0.0CysAsp: 0.0 ± 0.0
0.893CysGlu: 0.893 ± 0.434
0.447CysPhe: 0.447 ± 0.346
1.34CysGly: 1.34 ± 0.679
0.447CysHis: 0.447 ± 0.508
1.34CysIle: 1.34 ± 0.679
2.68CysLys: 2.68 ± 1.012
1.34CysLeu: 1.34 ± 0.595
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.787CysPro: 1.787 ± 0.839
0.447CysGln: 0.447 ± 0.508
1.34CysArg: 1.34 ± 0.992
0.447CysSer: 0.447 ± 0.346
1.34CysThr: 1.34 ± 0.769
0.893CysVal: 0.893 ± 0.645
0.893CysTrp: 0.893 ± 0.434
0.893CysTyr: 0.893 ± 0.568
0.0CysXaa: 0.0 ± 0.0
Asp
4.02AspAla: 4.02 ± 0.897
2.233AspCys: 2.233 ± 1.32
3.573AspAsp: 3.573 ± 0.685
3.126AspGlu: 3.126 ± 1.268
1.787AspPhe: 1.787 ± 0.746
3.126AspGly: 3.126 ± 0.945
0.447AspHis: 0.447 ± 0.346
6.699AspIle: 6.699 ± 2.156
1.787AspLys: 1.787 ± 0.937
6.699AspLeu: 6.699 ± 3.25
1.34AspMet: 1.34 ± 0.44
2.68AspAsn: 2.68 ± 0.506
3.573AspPro: 3.573 ± 1.929
2.68AspGln: 2.68 ± 0.772
0.447AspArg: 0.447 ± 0.528
3.573AspSer: 3.573 ± 1.515
5.36AspThr: 5.36 ± 0.909
5.36AspVal: 5.36 ± 0.605
0.893AspTrp: 0.893 ± 0.434
2.233AspTyr: 2.233 ± 1.305
0.0AspXaa: 0.0 ± 0.0
Glu
5.36GluAla: 5.36 ± 2.374
0.893GluCys: 0.893 ± 1.084
7.593GluAsp: 7.593 ± 1.051
7.593GluGlu: 7.593 ± 2.085
3.126GluPhe: 3.126 ± 0.971
4.02GluGly: 4.02 ± 1.407
0.893GluHis: 0.893 ± 0.434
4.02GluIle: 4.02 ± 1.686
2.68GluLys: 2.68 ± 1.626
4.466GluLeu: 4.466 ± 1.948
0.893GluMet: 0.893 ± 0.692
2.233GluAsn: 2.233 ± 0.512
2.68GluPro: 2.68 ± 0.415
4.466GluGln: 4.466 ± 0.817
3.126GluArg: 3.126 ± 1.524
4.02GluSer: 4.02 ± 1.362
4.913GluThr: 4.913 ± 1.747
1.787GluVal: 1.787 ± 1.097
0.893GluTrp: 0.893 ± 0.692
0.893GluTyr: 0.893 ± 0.58
0.0GluXaa: 0.0 ± 0.0
Phe
4.466PheAla: 4.466 ± 1.477
0.447PheCys: 0.447 ± 0.508
3.573PheAsp: 3.573 ± 1.159
2.233PheGlu: 2.233 ± 0.8
3.126PhePhe: 3.126 ± 0.815
2.233PheGly: 2.233 ± 0.704
0.447PheHis: 0.447 ± 0.395
2.233PheIle: 2.233 ± 0.728
4.913PheLys: 4.913 ± 2.032
4.913PheLeu: 4.913 ± 1.222
1.34PheMet: 1.34 ± 0.395
2.233PheAsn: 2.233 ± 1.159
2.233PhePro: 2.233 ± 1.246
2.233PheGln: 2.233 ± 0.902
3.573PheArg: 3.573 ± 1.424
1.34PheSer: 1.34 ± 0.739
2.233PheThr: 2.233 ± 0.395
1.787PheVal: 1.787 ± 0.759
1.34PheTrp: 1.34 ± 0.683
3.573PheTyr: 3.573 ± 0.873
0.0PheXaa: 0.0 ± 0.0
Gly
4.466GlyAla: 4.466 ± 1.613
0.893GlyCys: 0.893 ± 0.645
4.466GlyAsp: 4.466 ± 1.43
3.573GlyGlu: 3.573 ± 0.896
1.787GlyPhe: 1.787 ± 0.937
3.573GlyGly: 3.573 ± 1.981
0.447GlyHis: 0.447 ± 0.386
3.573GlyIle: 3.573 ± 0.985
3.126GlyLys: 3.126 ± 0.845
3.573GlyLeu: 3.573 ± 1.348
0.447GlyMet: 0.447 ± 0.475
4.466GlyAsn: 4.466 ± 0.605
1.34GlyPro: 1.34 ± 0.64
1.787GlyGln: 1.787 ± 0.607
3.573GlyArg: 3.573 ± 1.605
2.68GlySer: 2.68 ± 0.875
5.36GlyThr: 5.36 ± 2.006
3.126GlyVal: 3.126 ± 0.836
0.0GlyTrp: 0.0 ± 0.0
0.893GlyTyr: 0.893 ± 0.679
0.0GlyXaa: 0.0 ± 0.0
His
0.447HisAla: 0.447 ± 0.386
0.447HisCys: 0.447 ± 0.346
0.447HisAsp: 0.447 ± 0.346
0.0HisGlu: 0.0 ± 0.0
1.34HisPhe: 1.34 ± 0.476
0.893HisGly: 0.893 ± 0.692
0.893HisHis: 0.893 ± 1.056
2.233HisIle: 2.233 ± 1.306
0.893HisLys: 0.893 ± 0.692
1.787HisLeu: 1.787 ± 1.203
0.447HisMet: 0.447 ± 0.508
0.447HisAsn: 0.447 ± 0.395
1.787HisPro: 1.787 ± 0.909
0.447HisGln: 0.447 ± 0.435
0.447HisArg: 0.447 ± 0.528
0.893HisSer: 0.893 ± 0.692
0.893HisThr: 0.893 ± 0.508
0.893HisVal: 0.893 ± 0.508
1.787HisTrp: 1.787 ± 0.607
0.447HisTyr: 0.447 ± 0.346
0.0HisXaa: 0.0 ± 0.0
Ile
3.573IleAla: 3.573 ± 1.724
1.34IleCys: 1.34 ± 0.525
4.913IleAsp: 4.913 ± 2.504
4.466IleGlu: 4.466 ± 0.968
2.68IlePhe: 2.68 ± 0.779
3.573IleGly: 3.573 ± 1.883
0.893IleHis: 0.893 ± 0.692
1.34IleIle: 1.34 ± 0.745
2.68IleLys: 2.68 ± 1.199
5.36IleLeu: 5.36 ± 1.635
0.447IleMet: 0.447 ± 0.52
1.34IleAsn: 1.34 ± 0.751
3.573IlePro: 3.573 ± 1.085
3.126IleGln: 3.126 ± 1.002
1.34IleArg: 1.34 ± 0.98
6.699IleSer: 6.699 ± 0.455
3.573IleThr: 3.573 ± 0.716
3.126IleVal: 3.126 ± 1.136
0.0IleTrp: 0.0 ± 0.0
1.34IleTyr: 1.34 ± 0.791
0.0IleXaa: 0.0 ± 0.0
Lys
0.893LysAla: 0.893 ± 0.453
1.787LysCys: 1.787 ± 0.978
0.893LysAsp: 0.893 ± 0.542
2.68LysGlu: 2.68 ± 0.775
2.233LysPhe: 2.233 ± 0.703
2.68LysGly: 2.68 ± 1.162
2.233LysHis: 2.233 ± 1.249
1.34LysIle: 1.34 ± 1.039
3.573LysLys: 3.573 ± 1.542
4.466LysLeu: 4.466 ± 1.957
0.0LysMet: 0.0 ± 0.321
1.34LysAsn: 1.34 ± 0.683
1.787LysPro: 1.787 ± 0.568
3.126LysGln: 3.126 ± 1.222
4.913LysArg: 4.913 ± 1.307
4.466LysSer: 4.466 ± 1.923
3.573LysThr: 3.573 ± 1.984
3.126LysVal: 3.126 ± 1.045
0.893LysTrp: 0.893 ± 0.542
4.913LysTyr: 4.913 ± 1.156
0.0LysXaa: 0.0 ± 0.0
Leu
6.253LeuAla: 6.253 ± 1.903
2.233LeuCys: 2.233 ± 1.41
7.146LeuAsp: 7.146 ± 2.141
5.36LeuGlu: 5.36 ± 1.749
5.36LeuPhe: 5.36 ± 1.943
5.806LeuGly: 5.806 ± 1.822
2.233LeuHis: 2.233 ± 0.911
3.126LeuIle: 3.126 ± 1.579
4.02LeuLys: 4.02 ± 1.937
10.719LeuLeu: 10.719 ± 3.4
0.893LeuMet: 0.893 ± 0.907
2.233LeuAsn: 2.233 ± 0.793
4.913LeuPro: 4.913 ± 1.793
6.253LeuGln: 6.253 ± 1.734
5.806LeuArg: 5.806 ± 1.299
10.272LeuSer: 10.272 ± 2.007
5.36LeuThr: 5.36 ± 0.829
4.466LeuVal: 4.466 ± 1.288
0.893LeuTrp: 0.893 ± 0.434
3.126LeuTyr: 3.126 ± 1.127
0.0LeuXaa: 0.0 ± 0.0
Met
0.893MetAla: 0.893 ± 0.434
0.0MetCys: 0.0 ± 0.0
0.447MetAsp: 0.447 ± 0.386
1.787MetGlu: 1.787 ± 0.992
0.893MetPhe: 0.893 ± 0.453
0.447MetGly: 0.447 ± 0.395
0.893MetHis: 0.893 ± 0.453
1.787MetIle: 1.787 ± 0.759
0.893MetLys: 0.893 ± 0.601
0.447MetLeu: 0.447 ± 0.435
0.447MetMet: 0.447 ± 0.542
1.34MetAsn: 1.34 ± 1.159
0.447MetPro: 0.447 ± 0.346
0.893MetGln: 0.893 ± 0.453
0.893MetArg: 0.893 ± 0.542
1.787MetSer: 1.787 ± 1.105
0.447MetThr: 0.447 ± 0.346
1.34MetVal: 1.34 ± 0.683
0.447MetTrp: 0.447 ± 0.435
0.447MetTyr: 0.447 ± 0.386
0.0MetXaa: 0.0 ± 0.0
Asn
0.893AsnAla: 0.893 ± 0.692
1.34AsnCys: 1.34 ± 0.755
0.0AsnAsp: 0.0 ± 0.0
2.233AsnGlu: 2.233 ± 0.968
3.573AsnPhe: 3.573 ± 1.228
1.787AsnGly: 1.787 ± 0.622
0.0AsnHis: 0.0 ± 0.0
1.34AsnIle: 1.34 ± 0.37
1.787AsnLys: 1.787 ± 1.105
3.573AsnLeu: 3.573 ± 1.698
1.34AsnMet: 1.34 ± 0.37
2.233AsnAsn: 2.233 ± 0.652
4.02AsnPro: 4.02 ± 0.742
1.787AsnGln: 1.787 ± 0.868
2.233AsnArg: 2.233 ± 0.854
4.466AsnSer: 4.466 ± 1.229
3.126AsnThr: 3.126 ± 0.69
4.02AsnVal: 4.02 ± 1.265
0.447AsnTrp: 0.447 ± 0.435
0.447AsnTyr: 0.447 ± 0.346
0.0AsnXaa: 0.0 ± 0.0
Pro
4.466ProAla: 4.466 ± 1.516
0.893ProCys: 0.893 ± 0.773
4.02ProAsp: 4.02 ± 1.654
4.02ProGlu: 4.02 ± 1.81
3.126ProPhe: 3.126 ± 1.048
0.893ProGly: 0.893 ± 0.453
0.0ProHis: 0.0 ± 0.0
2.233ProIle: 2.233 ± 0.764
4.02ProLys: 4.02 ± 1.049
7.146ProLeu: 7.146 ± 0.963
0.447ProMet: 0.447 ± 0.508
3.126ProAsn: 3.126 ± 0.863
4.466ProPro: 4.466 ± 1.231
0.893ProGln: 0.893 ± 0.692
2.233ProArg: 2.233 ± 0.902
5.806ProSer: 5.806 ± 2.115
3.126ProThr: 3.126 ± 1.328
4.466ProVal: 4.466 ± 0.96
0.447ProTrp: 0.447 ± 0.435
2.233ProTyr: 2.233 ± 1.088
0.0ProXaa: 0.0 ± 0.0
Gln
0.893GlnAla: 0.893 ± 0.542
0.893GlnCys: 0.893 ± 0.542
0.893GlnAsp: 0.893 ± 0.673
6.253GlnGlu: 6.253 ± 1.914
4.02GlnPhe: 4.02 ± 0.879
1.34GlnGly: 1.34 ± 0.44
0.893GlnHis: 0.893 ± 0.87
4.02GlnIle: 4.02 ± 1.414
0.0GlnLys: 0.0 ± 0.0
3.573GlnLeu: 3.573 ± 1.216
1.34GlnMet: 1.34 ± 1.159
2.233GlnAsn: 2.233 ± 1.06
2.68GlnPro: 2.68 ± 0.494
2.68GlnGln: 2.68 ± 0.415
2.68GlnArg: 2.68 ± 1.035
1.787GlnSer: 1.787 ± 0.76
4.02GlnThr: 4.02 ± 1.275
2.233GlnVal: 2.233 ± 1.078
0.447GlnTrp: 0.447 ± 0.435
1.34GlnTyr: 1.34 ± 0.44
0.0GlnXaa: 0.0 ± 0.0
Arg
2.68ArgAla: 2.68 ± 0.82
1.34ArgCys: 1.34 ± 0.755
2.68ArgAsp: 2.68 ± 0.747
3.573ArgGlu: 3.573 ± 1.092
1.787ArgPhe: 1.787 ± 1.057
3.573ArgGly: 3.573 ± 0.889
2.233ArgHis: 2.233 ± 0.734
3.573ArgIle: 3.573 ± 1.153
2.68ArgLys: 2.68 ± 0.56
8.039ArgLeu: 8.039 ± 1.713
1.34ArgMet: 1.34 ± 0.864
2.233ArgAsn: 2.233 ± 0.764
3.573ArgPro: 3.573 ± 1.297
2.233ArgGln: 2.233 ± 0.62
5.806ArgArg: 5.806 ± 1.85
4.466ArgSer: 4.466 ± 0.574
5.36ArgThr: 5.36 ± 1.592
1.787ArgVal: 1.787 ± 0.867
0.0ArgTrp: 0.0 ± 0.0
1.34ArgTyr: 1.34 ± 0.864
0.0ArgXaa: 0.0 ± 0.0
Ser
7.146SerAla: 7.146 ± 1.285
0.0SerCys: 0.0 ± 0.0
3.126SerAsp: 3.126 ± 0.943
2.233SerGlu: 2.233 ± 0.62
4.02SerPhe: 4.02 ± 1.032
4.913SerGly: 4.913 ± 1.42
2.233SerHis: 2.233 ± 0.795
3.573SerIle: 3.573 ± 1.146
4.913SerLys: 4.913 ± 1.456
9.379SerLeu: 9.379 ± 1.031
0.893SerMet: 0.893 ± 0.626
4.466SerAsn: 4.466 ± 1.356
3.573SerPro: 3.573 ± 1.441
1.34SerGln: 1.34 ± 1.039
4.466SerArg: 4.466 ± 1.33
4.02SerSer: 4.02 ± 1.052
4.913SerThr: 4.913 ± 0.701
4.02SerVal: 4.02 ± 1.717
0.0SerTrp: 0.0 ± 0.0
2.68SerTyr: 2.68 ± 0.889
0.0SerXaa: 0.0 ± 0.0
Thr
3.126ThrAla: 3.126 ± 1.273
0.893ThrCys: 0.893 ± 0.542
6.253ThrAsp: 6.253 ± 1.551
4.02ThrGlu: 4.02 ± 1.265
4.913ThrPhe: 4.913 ± 1.424
2.68ThrGly: 2.68 ± 1.055
0.893ThrHis: 0.893 ± 0.601
3.573ThrIle: 3.573 ± 0.974
2.233ThrLys: 2.233 ± 0.675
6.253ThrLeu: 6.253 ± 1.489
2.233ThrMet: 2.233 ± 1.301
2.68ThrAsn: 2.68 ± 0.739
4.913ThrPro: 4.913 ± 1.97
3.126ThrGln: 3.126 ± 1.385
2.233ThrArg: 2.233 ± 0.917
6.253ThrSer: 6.253 ± 1.802
4.913ThrThr: 4.913 ± 1.458
6.253ThrVal: 6.253 ± 2.19
0.447ThrTrp: 0.447 ± 0.435
0.893ThrTyr: 0.893 ± 0.508
0.0ThrXaa: 0.0 ± 0.0
Val
5.36ValAla: 5.36 ± 1.078
0.893ValCys: 0.893 ± 0.566
6.253ValAsp: 6.253 ± 1.495
5.806ValGlu: 5.806 ± 1.701
1.787ValPhe: 1.787 ± 0.888
3.573ValGly: 3.573 ± 1.366
1.34ValHis: 1.34 ± 0.751
0.893ValIle: 0.893 ± 0.431
0.893ValLys: 0.893 ± 0.566
4.02ValLeu: 4.02 ± 0.477
0.893ValMet: 0.893 ± 0.525
1.34ValAsn: 1.34 ± 0.631
7.146ValPro: 7.146 ± 1.985
4.02ValGln: 4.02 ± 0.881
4.02ValArg: 4.02 ± 1.09
1.787ValSer: 1.787 ± 0.69
2.233ValThr: 2.233 ± 1.225
4.466ValVal: 4.466 ± 1.437
0.893ValTrp: 0.893 ± 0.566
2.233ValTyr: 2.233 ± 0.588
0.0ValXaa: 0.0 ± 0.0
Trp
0.893TrpAla: 0.893 ± 0.773
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.893TrpPhe: 0.893 ± 0.692
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.34TrpIle: 1.34 ± 0.683
1.34TrpLys: 1.34 ± 0.679
2.233TrpLeu: 2.233 ± 1.091
0.0TrpMet: 0.0 ± 0.0
0.447TrpAsn: 0.447 ± 0.386
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.893TrpArg: 0.893 ± 1.016
0.447TrpSer: 0.447 ± 0.346
2.68TrpThr: 2.68 ± 1.575
0.893TrpVal: 0.893 ± 0.453
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.233TyrAla: 2.233 ± 0.818
0.447TyrCys: 0.447 ± 0.542
0.447TyrAsp: 0.447 ± 0.346
2.233TyrGlu: 2.233 ± 0.795
0.893TyrPhe: 0.893 ± 0.508
4.02TyrGly: 4.02 ± 1.067
0.447TyrHis: 0.447 ± 0.386
4.02TyrIle: 4.02 ± 1.389
1.787TyrLys: 1.787 ± 0.623
3.126TyrLeu: 3.126 ± 0.99
0.447TyrMet: 0.447 ± 0.346
1.787TyrAsn: 1.787 ± 0.693
0.447TyrPro: 0.447 ± 0.386
0.893TyrGln: 0.893 ± 0.434
2.233TyrArg: 2.233 ± 0.83
2.68TyrSer: 2.68 ± 0.678
1.787TyrThr: 1.787 ± 0.711
1.787TyrVal: 1.787 ± 0.267
0.447TyrTrp: 0.447 ± 0.386
2.233TyrTyr: 2.233 ± 1.303
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2240 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski