Amino acid dipepetide frequency for Enterobacteria phage T3 (Bacteriophage T3)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.268AlaAla: 10.268 ± 1.042
0.675AlaCys: 0.675 ± 0.205
5.846AlaAsp: 5.846 ± 0.841
5.846AlaGlu: 5.846 ± 0.531
3.148AlaPhe: 3.148 ± 0.501
8.019AlaGly: 8.019 ± 0.778
1.499AlaHis: 1.499 ± 0.205
4.797AlaIle: 4.797 ± 0.416
6.22AlaLys: 6.22 ± 0.681
8.993AlaLeu: 8.993 ± 0.792
3.448AlaMet: 3.448 ± 0.545
4.047AlaAsn: 4.047 ± 0.565
2.698AlaPro: 2.698 ± 0.443
3.597AlaGln: 3.597 ± 0.528
5.396AlaArg: 5.396 ± 0.677
4.871AlaSer: 4.871 ± 0.58
4.122AlaThr: 4.122 ± 0.564
5.321AlaVal: 5.321 ± 0.728
1.874AlaTrp: 1.874 ± 0.31
2.548AlaTyr: 2.548 ± 0.448
0.0AlaXaa: 0.0 ± 0.0
Cys
0.749CysAla: 0.749 ± 0.229
0.225CysCys: 0.225 ± 0.126
0.974CysAsp: 0.974 ± 0.399
0.45CysGlu: 0.45 ± 0.219
0.6CysPhe: 0.6 ± 0.243
0.824CysGly: 0.824 ± 0.262
0.6CysHis: 0.6 ± 0.261
0.675CysIle: 0.675 ± 0.253
0.899CysLys: 0.899 ± 0.278
1.199CysLeu: 1.199 ± 0.429
0.075CysMet: 0.075 ± 0.066
0.3CysAsn: 0.3 ± 0.137
0.3CysPro: 0.3 ± 0.16
0.6CysGln: 0.6 ± 0.235
0.6CysArg: 0.6 ± 0.24
0.6CysSer: 0.6 ± 0.295
0.45CysThr: 0.45 ± 0.215
0.6CysVal: 0.6 ± 0.193
0.225CysTrp: 0.225 ± 0.15
0.525CysTyr: 0.525 ± 0.223
0.0CysXaa: 0.0 ± 0.0
Asp
5.621AspAla: 5.621 ± 0.585
0.899AspCys: 0.899 ± 0.289
4.272AspAsp: 4.272 ± 0.6
4.272AspGlu: 4.272 ± 0.694
2.548AspPhe: 2.548 ± 0.343
7.045AspGly: 7.045 ± 0.801
1.124AspHis: 1.124 ± 0.284
2.698AspIle: 2.698 ± 0.351
4.722AspLys: 4.722 ± 0.641
3.522AspLeu: 3.522 ± 0.619
2.024AspMet: 2.024 ± 0.467
2.698AspAsn: 2.698 ± 0.329
3.223AspPro: 3.223 ± 0.548
1.874AspGln: 1.874 ± 0.47
3.073AspArg: 3.073 ± 0.556
3.672AspSer: 3.672 ± 0.606
3.672AspThr: 3.672 ± 0.526
4.197AspVal: 4.197 ± 0.411
0.45AspTrp: 0.45 ± 0.218
1.799AspTyr: 1.799 ± 0.297
0.0AspXaa: 0.0 ± 0.0
Glu
7.27GluAla: 7.27 ± 0.688
0.675GluCys: 0.675 ± 0.222
4.722GluAsp: 4.722 ± 0.649
5.096GluGlu: 5.096 ± 0.653
2.398GluPhe: 2.398 ± 0.396
4.422GluGly: 4.422 ± 0.615
1.424GluHis: 1.424 ± 0.373
3.448GluIle: 3.448 ± 0.515
4.272GluLys: 4.272 ± 0.624
5.996GluLeu: 5.996 ± 0.634
2.173GluMet: 2.173 ± 0.381
2.248GluAsn: 2.248 ± 0.375
1.649GluPro: 1.649 ± 0.359
4.197GluGln: 4.197 ± 0.799
4.197GluArg: 4.197 ± 0.446
4.347GluSer: 4.347 ± 0.434
2.623GluThr: 2.623 ± 0.51
4.197GluVal: 4.197 ± 0.454
1.499GluTrp: 1.499 ± 0.353
2.698GluTyr: 2.698 ± 0.478
0.0GluXaa: 0.0 ± 0.0
Phe
2.323PheAla: 2.323 ± 0.357
0.375PheCys: 0.375 ± 0.175
3.073PheAsp: 3.073 ± 0.487
2.398PheGlu: 2.398 ± 0.38
1.124PhePhe: 1.124 ± 0.32
3.073PheGly: 3.073 ± 0.39
1.049PheHis: 1.049 ± 0.384
1.874PheIle: 1.874 ± 0.407
2.773PheLys: 2.773 ± 0.443
2.998PheLeu: 2.998 ± 0.391
1.124PheMet: 1.124 ± 0.225
1.499PheAsn: 1.499 ± 0.381
1.574PhePro: 1.574 ± 0.37
1.349PheGln: 1.349 ± 0.263
1.799PheArg: 1.799 ± 0.351
1.574PheSer: 1.574 ± 0.4
2.923PheThr: 2.923 ± 0.493
1.724PheVal: 1.724 ± 0.336
0.15PheTrp: 0.15 ± 0.09
1.199PheTyr: 1.199 ± 0.31
0.0PheXaa: 0.0 ± 0.0
Gly
6.97GlyAla: 6.97 ± 0.842
1.274GlyCys: 1.274 ± 0.374
5.171GlyAsp: 5.171 ± 0.63
5.246GlyGlu: 5.246 ± 0.657
3.522GlyPhe: 3.522 ± 0.522
5.096GlyGly: 5.096 ± 0.721
1.274GlyHis: 1.274 ± 0.31
4.497GlyIle: 4.497 ± 0.62
5.846GlyLys: 5.846 ± 0.755
6.745GlyLeu: 6.745 ± 0.756
2.098GlyMet: 2.098 ± 0.366
2.848GlyAsn: 2.848 ± 0.473
0.899GlyPro: 0.899 ± 0.343
3.073GlyGln: 3.073 ± 0.456
4.572GlyArg: 4.572 ± 0.486
4.572GlySer: 4.572 ± 0.576
2.998GlyThr: 2.998 ± 0.556
4.347GlyVal: 4.347 ± 0.453
1.499GlyTrp: 1.499 ± 0.392
2.548GlyTyr: 2.548 ± 0.417
0.0GlyXaa: 0.0 ± 0.0
His
1.724HisAla: 1.724 ± 0.373
0.225HisCys: 0.225 ± 0.123
0.824HisAsp: 0.824 ± 0.212
1.199HisGlu: 1.199 ± 0.349
0.824HisPhe: 0.824 ± 0.257
1.499HisGly: 1.499 ± 0.281
0.6HisHis: 0.6 ± 0.222
1.499HisIle: 1.499 ± 0.307
1.124HisLys: 1.124 ± 0.331
2.248HisLeu: 2.248 ± 0.464
0.749HisMet: 0.749 ± 0.201
0.6HisAsn: 0.6 ± 0.188
0.45HisPro: 0.45 ± 0.185
0.075HisGln: 0.075 ± 0.071
1.049HisArg: 1.049 ± 0.266
1.424HisSer: 1.424 ± 0.374
0.824HisThr: 0.824 ± 0.205
1.424HisVal: 1.424 ± 0.328
0.525HisTrp: 0.525 ± 0.181
0.6HisTyr: 0.6 ± 0.191
0.0HisXaa: 0.0 ± 0.0
Ile
4.272IleAla: 4.272 ± 0.617
0.675IleCys: 0.675 ± 0.215
3.597IleAsp: 3.597 ± 0.376
3.597IleGlu: 3.597 ± 0.63
1.199IlePhe: 1.199 ± 0.263
3.148IleGly: 3.148 ± 0.399
1.499IleHis: 1.499 ± 0.375
2.998IleIle: 2.998 ± 0.368
3.522IleLys: 3.522 ± 0.483
3.597IleLeu: 3.597 ± 0.423
0.824IleMet: 0.824 ± 0.233
2.698IleAsn: 2.698 ± 0.656
2.848IlePro: 2.848 ± 0.378
2.173IleGln: 2.173 ± 0.419
2.773IleArg: 2.773 ± 0.521
2.923IleSer: 2.923 ± 0.404
1.949IleThr: 1.949 ± 0.343
3.223IleVal: 3.223 ± 0.342
0.6IleTrp: 0.6 ± 0.218
1.724IleTyr: 1.724 ± 0.281
0.0IleXaa: 0.0 ± 0.0
Lys
7.644LysAla: 7.644 ± 0.947
0.45LysCys: 0.45 ± 0.18
3.148LysAsp: 3.148 ± 0.348
5.171LysGlu: 5.171 ± 0.7
2.473LysPhe: 2.473 ± 0.427
4.722LysGly: 4.722 ± 0.597
1.874LysHis: 1.874 ± 0.349
1.649LysIle: 1.649 ± 0.238
4.797LysLys: 4.797 ± 0.863
5.321LysLeu: 5.321 ± 0.659
1.799LysMet: 1.799 ± 0.378
2.173LysAsn: 2.173 ± 0.299
3.298LysPro: 3.298 ± 0.582
2.024LysGln: 2.024 ± 0.473
4.497LysArg: 4.497 ± 0.646
3.672LysSer: 3.672 ± 0.654
3.522LysThr: 3.522 ± 0.437
5.471LysVal: 5.471 ± 0.584
0.974LysTrp: 0.974 ± 0.245
2.024LysTyr: 2.024 ± 0.32
0.0LysXaa: 0.0 ± 0.0
Leu
8.244LeuAla: 8.244 ± 1.166
0.45LeuCys: 0.45 ± 0.208
4.871LeuAsp: 4.871 ± 0.477
6.295LeuGlu: 6.295 ± 0.768
2.548LeuPhe: 2.548 ± 0.522
4.497LeuGly: 4.497 ± 0.658
0.824LeuHis: 0.824 ± 0.333
3.897LeuIle: 3.897 ± 0.462
5.921LeuLys: 5.921 ± 0.542
4.946LeuLeu: 4.946 ± 0.721
2.548LeuMet: 2.548 ± 0.392
4.122LeuAsn: 4.122 ± 0.502
3.672LeuPro: 3.672 ± 0.428
3.672LeuGln: 3.672 ± 0.473
6.37LeuArg: 6.37 ± 0.618
4.797LeuSer: 4.797 ± 0.653
5.771LeuThr: 5.771 ± 0.881
5.396LeuVal: 5.396 ± 0.521
1.274LeuTrp: 1.274 ± 0.347
2.548LeuTyr: 2.548 ± 0.494
0.0LeuXaa: 0.0 ± 0.0
Met
2.998MetAla: 2.998 ± 0.376
0.225MetCys: 0.225 ± 0.129
2.024MetAsp: 2.024 ± 0.491
1.874MetGlu: 1.874 ± 0.55
0.974MetPhe: 0.974 ± 0.245
2.623MetGly: 2.623 ± 0.521
0.45MetHis: 0.45 ± 0.199
1.349MetIle: 1.349 ± 0.285
1.124MetLys: 1.124 ± 0.313
3.672MetLeu: 3.672 ± 0.454
1.124MetMet: 1.124 ± 0.297
1.499MetAsn: 1.499 ± 0.282
1.724MetPro: 1.724 ± 0.259
1.124MetGln: 1.124 ± 0.321
1.349MetArg: 1.349 ± 0.274
1.349MetSer: 1.349 ± 0.277
1.874MetThr: 1.874 ± 0.337
2.173MetVal: 2.173 ± 0.332
0.075MetTrp: 0.075 ± 0.066
0.6MetTyr: 0.6 ± 0.259
0.0MetXaa: 0.0 ± 0.0
Asn
3.522AsnAla: 3.522 ± 0.403
0.525AsnCys: 0.525 ± 0.246
2.323AsnAsp: 2.323 ± 0.438
2.773AsnGlu: 2.773 ± 0.406
1.574AsnPhe: 1.574 ± 0.292
3.972AsnGly: 3.972 ± 0.599
0.375AsnHis: 0.375 ± 0.17
2.473AsnIle: 2.473 ± 0.475
2.098AsnLys: 2.098 ± 0.318
3.373AsnLeu: 3.373 ± 0.512
0.899AsnMet: 0.899 ± 0.248
1.949AsnAsn: 1.949 ± 0.437
2.248AsnPro: 2.248 ± 0.484
2.173AsnGln: 2.173 ± 0.348
2.323AsnArg: 2.323 ± 0.598
2.398AsnSer: 2.398 ± 0.69
2.098AsnThr: 2.098 ± 0.348
2.548AsnVal: 2.548 ± 0.463
0.6AsnTrp: 0.6 ± 0.206
2.024AsnTyr: 2.024 ± 0.513
0.0AsnXaa: 0.0 ± 0.0
Pro
2.848ProAla: 2.848 ± 0.353
0.675ProCys: 0.675 ± 0.274
3.148ProAsp: 3.148 ± 0.42
3.148ProGlu: 3.148 ± 0.64
1.199ProPhe: 1.199 ± 0.309
1.649ProGly: 1.649 ± 0.294
0.6ProHis: 0.6 ± 0.171
1.649ProIle: 1.649 ± 0.337
2.773ProLys: 2.773 ± 0.469
2.323ProLeu: 2.323 ± 0.535
1.124ProMet: 1.124 ± 0.291
2.248ProAsn: 2.248 ± 0.456
0.899ProPro: 0.899 ± 0.303
1.124ProGln: 1.124 ± 0.333
1.949ProArg: 1.949 ± 0.363
2.024ProSer: 2.024 ± 0.299
2.398ProThr: 2.398 ± 0.375
2.248ProVal: 2.248 ± 0.388
0.749ProTrp: 0.749 ± 0.167
1.349ProTyr: 1.349 ± 0.341
0.0ProXaa: 0.0 ± 0.0
Gln
3.747GlnAla: 3.747 ± 0.575
0.525GlnCys: 0.525 ± 0.231
2.248GlnAsp: 2.248 ± 0.39
3.298GlnGlu: 3.298 ± 0.491
1.799GlnPhe: 1.799 ± 0.309
2.773GlnGly: 2.773 ± 0.396
0.675GlnHis: 0.675 ± 0.203
1.799GlnIle: 1.799 ± 0.392
2.098GlnLys: 2.098 ± 0.315
3.822GlnLeu: 3.822 ± 0.436
1.049GlnMet: 1.049 ± 0.275
1.124GlnAsn: 1.124 ± 0.224
1.199GlnPro: 1.199 ± 0.339
1.874GlnGln: 1.874 ± 0.235
2.024GlnArg: 2.024 ± 0.513
2.323GlnSer: 2.323 ± 0.453
2.098GlnThr: 2.098 ± 0.351
2.548GlnVal: 2.548 ± 0.456
0.899GlnTrp: 0.899 ± 0.257
1.274GlnTyr: 1.274 ± 0.324
0.0GlnXaa: 0.0 ± 0.0
Arg
5.246ArgAla: 5.246 ± 0.594
1.124ArgCys: 1.124 ± 0.292
3.897ArgAsp: 3.897 ± 0.54
4.946ArgGlu: 4.946 ± 0.706
2.773ArgPhe: 2.773 ± 0.476
3.672ArgGly: 3.672 ± 0.41
1.499ArgHis: 1.499 ± 0.367
2.623ArgIle: 2.623 ± 0.416
3.448ArgLys: 3.448 ± 0.587
5.321ArgLeu: 5.321 ± 0.588
2.098ArgMet: 2.098 ± 0.524
2.623ArgAsn: 2.623 ± 0.488
1.124ArgPro: 1.124 ± 0.246
1.949ArgGln: 1.949 ± 0.414
3.148ArgArg: 3.148 ± 0.457
4.197ArgSer: 4.197 ± 0.572
3.148ArgThr: 3.148 ± 0.459
3.672ArgVal: 3.672 ± 0.516
0.974ArgTrp: 0.974 ± 0.274
1.199ArgTyr: 1.199 ± 0.167
0.0ArgXaa: 0.0 ± 0.0
Ser
6.071SerAla: 6.071 ± 0.745
0.824SerCys: 0.824 ± 0.367
4.946SerAsp: 4.946 ± 0.76
2.698SerGlu: 2.698 ± 0.414
2.173SerPhe: 2.173 ± 0.357
4.797SerGly: 4.797 ± 0.585
1.124SerHis: 1.124 ± 0.278
3.298SerIle: 3.298 ± 0.515
3.223SerLys: 3.223 ± 0.536
3.972SerLeu: 3.972 ± 0.539
1.424SerMet: 1.424 ± 0.368
2.173SerAsn: 2.173 ± 0.32
1.574SerPro: 1.574 ± 0.379
2.398SerGln: 2.398 ± 0.361
3.672SerArg: 3.672 ± 0.583
3.672SerSer: 3.672 ± 0.732
3.672SerThr: 3.672 ± 0.568
4.122SerVal: 4.122 ± 0.506
0.749SerTrp: 0.749 ± 0.152
2.248SerTyr: 2.248 ± 0.478
0.0SerXaa: 0.0 ± 0.0
Thr
4.497ThrAla: 4.497 ± 0.754
0.6ThrCys: 0.6 ± 0.238
2.548ThrAsp: 2.548 ± 0.386
3.822ThrGlu: 3.822 ± 0.501
1.949ThrPhe: 1.949 ± 0.324
5.396ThrGly: 5.396 ± 0.8
1.199ThrHis: 1.199 ± 0.29
3.223ThrIle: 3.223 ± 0.401
4.047ThrLys: 4.047 ± 0.414
5.246ThrLeu: 5.246 ± 0.714
2.098ThrMet: 2.098 ± 0.376
1.799ThrAsn: 1.799 ± 0.387
2.848ThrPro: 2.848 ± 0.451
1.649ThrGln: 1.649 ± 0.314
2.024ThrArg: 2.024 ± 0.302
3.897ThrSer: 3.897 ± 0.577
2.998ThrThr: 2.998 ± 0.47
3.148ThrVal: 3.148 ± 0.512
0.45ThrTrp: 0.45 ± 0.295
1.274ThrTyr: 1.274 ± 0.281
0.0ThrXaa: 0.0 ± 0.0
Val
5.471ValAla: 5.471 ± 0.475
0.375ValCys: 0.375 ± 0.168
3.148ValAsp: 3.148 ± 0.466
4.347ValGlu: 4.347 ± 0.669
1.874ValPhe: 1.874 ± 0.344
4.572ValGly: 4.572 ± 0.599
1.049ValHis: 1.049 ± 0.263
3.148ValIle: 3.148 ± 0.493
4.871ValLys: 4.871 ± 0.65
5.021ValLeu: 5.021 ± 0.686
1.949ValMet: 1.949 ± 0.386
3.073ValAsn: 3.073 ± 0.54
2.848ValPro: 2.848 ± 0.384
2.098ValGln: 2.098 ± 0.385
4.946ValArg: 4.946 ± 0.675
3.373ValSer: 3.373 ± 0.568
4.497ValThr: 4.497 ± 0.421
5.621ValVal: 5.621 ± 0.656
1.499ValTrp: 1.499 ± 0.291
1.949ValTyr: 1.949 ± 0.528
0.0ValXaa: 0.0 ± 0.0
Trp
0.675TrpAla: 0.675 ± 0.201
0.45TrpCys: 0.45 ± 0.197
0.525TrpAsp: 0.525 ± 0.198
1.124TrpGlu: 1.124 ± 0.271
0.3TrpPhe: 0.3 ± 0.178
1.049TrpGly: 1.049 ± 0.307
0.3TrpHis: 0.3 ± 0.191
0.675TrpIle: 0.675 ± 0.28
1.424TrpLys: 1.424 ± 0.402
1.649TrpLeu: 1.649 ± 0.389
0.6TrpMet: 0.6 ± 0.186
1.424TrpAsn: 1.424 ± 0.297
0.3TrpPro: 0.3 ± 0.152
0.675TrpGln: 0.675 ± 0.225
0.749TrpArg: 0.749 ± 0.193
1.049TrpSer: 1.049 ± 0.302
0.974TrpThr: 0.974 ± 0.248
1.499TrpVal: 1.499 ± 0.423
0.375TrpTrp: 0.375 ± 0.168
0.3TrpTyr: 0.3 ± 0.129
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.073TyrAla: 3.073 ± 0.439
0.225TyrCys: 0.225 ± 0.108
2.098TyrAsp: 2.098 ± 0.522
1.949TyrGlu: 1.949 ± 0.405
0.974TyrPhe: 0.974 ± 0.29
2.248TyrGly: 2.248 ± 0.4
0.45TyrHis: 0.45 ± 0.183
1.574TyrIle: 1.574 ± 0.367
1.499TyrLys: 1.499 ± 0.373
2.698TyrLeu: 2.698 ± 0.43
0.899TyrMet: 0.899 ± 0.221
1.124TyrAsn: 1.124 ± 0.231
0.749TyrPro: 0.749 ± 0.207
1.574TyrGln: 1.574 ± 0.403
2.173TyrArg: 2.173 ± 0.377
2.098TyrSer: 2.098 ± 0.297
2.098TyrThr: 2.098 ± 0.377
2.248TyrVal: 2.248 ± 0.399
0.675TyrTrp: 0.675 ± 0.227
0.3TyrTyr: 0.3 ± 0.17
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 55 proteins (13344 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski