Amino acid dipepetide frequency for Salipiger marinus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.291AlaAla: 19.291 ± 0.156	1.204AlaCys: 1.204 ± 0.03	6.992AlaAsp: 6.992 ± 0.075	9.305AlaGlu: 9.305 ± 0.103	4.174AlaPhe: 4.174 ± 0.059	11.371AlaGly: 11.371 ± 0.106	2.392AlaHis: 2.392 ± 0.047	5.29AlaIle: 5.29 ± 0.067	2.865AlaLys: 2.865 ± 0.05	16.13AlaLeu: 16.13 ± 0.137	3.839AlaMet: 3.839 ± 0.049	2.201AlaAsn: 2.201 ± 0.039	6.951AlaPro: 6.951 ± 0.085	5.251AlaGln: 5.251 ± 0.062	10.72AlaArg: 10.72 ± 0.101	5.656AlaSer: 5.656 ± 0.055	6.107AlaThr: 6.107 ± 0.058	8.879AlaVal: 8.879 ± 0.082	1.487AlaTrp: 1.487 ± 0.032	2.385AlaTyr: 2.385 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	1.244CysAla: 1.244 ± 0.033	0.119CysCys: 0.119 ± 0.009	0.598CysAsp: 0.598 ± 0.021	0.41CysGlu: 0.41 ± 0.016	0.322CysPhe: 0.322 ± 0.013	1.002CysGly: 1.002 ± 0.028	0.253CysHis: 0.253 ± 0.013	0.359CysIle: 0.359 ± 0.015	0.148CysLys: 0.148 ± 0.01	0.921CysLeu: 0.921 ± 0.027	0.147CysMet: 0.147 ± 0.009	0.172CysAsn: 0.172 ± 0.01	0.535CysPro: 0.535 ± 0.021	0.228CysGln: 0.228 ± 0.011	0.634CysArg: 0.634 ± 0.02	0.397CysSer: 0.397 ± 0.016	0.428CysThr: 0.428 ± 0.017	0.605CysVal: 0.605 ± 0.019	0.138CysTrp: 0.138 ± 0.009	0.184CysTyr: 0.184 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.944AspAla: 6.944 ± 0.081	0.516AspCys: 0.516 ± 0.017	2.794AspAsp: 2.794 ± 0.061	3.017AspGlu: 3.017 ± 0.045	2.09AspPhe: 2.09 ± 0.036	5.267AspGly: 5.267 ± 0.067	1.426AspHis: 1.426 ± 0.029	2.621AspIle: 2.621 ± 0.041	1.174AspLys: 1.174 ± 0.029	7.482AspLeu: 7.482 ± 0.077	1.67AspMet: 1.67 ± 0.032	1.054AspAsn: 1.054 ± 0.029	4.232AspPro: 4.232 ± 0.059	1.891AspGln: 1.891 ± 0.035	5.064AspArg: 5.064 ± 0.064	2.441AspSer: 2.441 ± 0.039	2.919AspThr: 2.919 ± 0.056	3.809AspVal: 3.809 ± 0.057	1.321AspTrp: 1.321 ± 0.026	1.423AspTyr: 1.423 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	8.913GluAla: 8.913 ± 0.087	0.268GluCys: 0.268 ± 0.011	3.444GluAsp: 3.444 ± 0.049	3.423GluGlu: 3.423 ± 0.059	1.763GluPhe: 1.763 ± 0.034	5.105GluGly: 5.105 ± 0.065	1.07GluHis: 1.07 ± 0.023	3.258GluIle: 3.258 ± 0.041	1.583GluLys: 1.583 ± 0.035	4.723GluLeu: 4.723 ± 0.055	1.695GluMet: 1.695 ± 0.038	1.344GluAsn: 1.344 ± 0.031	2.666GluPro: 2.666 ± 0.043	1.902GluGln: 1.902 ± 0.033	4.045GluArg: 4.045 ± 0.057	2.006GluSer: 2.006 ± 0.033	3.496GluThr: 3.496 ± 0.05	4.375GluVal: 4.375 ± 0.055	0.564GluTrp: 0.564 ± 0.019	0.853GluTyr: 0.853 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	4.553PheAla: 4.553 ± 0.054	0.402PheCys: 0.402 ± 0.017	2.717PheAsp: 2.717 ± 0.046	1.884PheGlu: 1.884 ± 0.037	1.301PhePhe: 1.301 ± 0.032	3.623PheGly: 3.623 ± 0.048	0.729PheHis: 0.729 ± 0.023	1.387PheIle: 1.387 ± 0.03	0.629PheLys: 0.629 ± 0.02	3.414PheLeu: 3.414 ± 0.053	0.746PheMet: 0.746 ± 0.023	0.889PheAsn: 0.889 ± 0.025	1.542PhePro: 1.542 ± 0.032	0.941PheGln: 0.941 ± 0.024	2.379PheArg: 2.379 ± 0.044	1.88PheSer: 1.88 ± 0.031	1.997PheThr: 1.997 ± 0.036	2.641PheVal: 2.641 ± 0.049	0.518PheTrp: 0.518 ± 0.02	0.812PheTyr: 0.812 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	10.777GlyAla: 10.777 ± 0.096	0.883GlyCys: 0.883 ± 0.025	4.409GlyAsp: 4.409 ± 0.081	4.447GlyGlu: 4.447 ± 0.054	3.663GlyPhe: 3.663 ± 0.043	7.75GlyGly: 7.75 ± 0.091	2.008GlyHis: 2.008 ± 0.041	4.325GlyIle: 4.325 ± 0.05	2.406GlyLys: 2.406 ± 0.04	10.306GlyLeu: 10.306 ± 0.105	2.63GlyMet: 2.63 ± 0.041	1.88GlyAsn: 1.88 ± 0.042	4.008GlyPro: 4.008 ± 0.051	3.41GlyGln: 3.41 ± 0.049	6.538GlyArg: 6.538 ± 0.069	4.484GlySer: 4.484 ± 0.061	4.833GlyThr: 4.833 ± 0.054	6.277GlyVal: 6.277 ± 0.066	1.619GlyTrp: 1.619 ± 0.034	2.181GlyTyr: 2.181 ± 0.038	0.0GlyXaa: 0.0 ± 0.0
His	2.437HisAla: 2.437 ± 0.043	0.234HisCys: 0.234 ± 0.012	1.335HisAsp: 1.335 ± 0.03	0.968HisGlu: 0.968 ± 0.027	0.745HisPhe: 0.745 ± 0.02	1.99HisGly: 1.99 ± 0.04	0.583HisHis: 0.583 ± 0.02	0.804HisIle: 0.804 ± 0.023	0.423HisLys: 0.423 ± 0.018	2.424HisLeu: 2.424 ± 0.04	0.542HisMet: 0.542 ± 0.017	0.377HisAsn: 0.377 ± 0.014	1.456HisPro: 1.456 ± 0.034	0.572HisGln: 0.572 ± 0.019	1.508HisArg: 1.508 ± 0.034	0.849HisSer: 0.849 ± 0.026	0.71HisThr: 0.71 ± 0.022	1.666HisVal: 1.666 ± 0.033	0.375HisTrp: 0.375 ± 0.016	0.49HisTyr: 0.49 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	6.52IleAla: 6.52 ± 0.067	0.572IleCys: 0.572 ± 0.02	3.068IleAsp: 3.068 ± 0.046	2.875IleGlu: 2.875 ± 0.04	1.744IlePhe: 1.744 ± 0.036	4.23IleGly: 4.23 ± 0.053	0.852IleHis: 0.852 ± 0.024	1.71IleIle: 1.71 ± 0.039	0.93IleLys: 0.93 ± 0.026	4.714IleLeu: 4.714 ± 0.061	0.912IleMet: 0.912 ± 0.026	1.039IleAsn: 1.039 ± 0.027	2.239IlePro: 2.239 ± 0.041	0.962IleGln: 0.962 ± 0.023	3.263IleArg: 3.263 ± 0.05	2.549IleSer: 2.549 ± 0.04	2.707IleThr: 2.707 ± 0.041	3.318IleVal: 3.318 ± 0.052	0.642IleTrp: 0.642 ± 0.024	1.034IleTyr: 1.034 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.062LysAla: 3.062 ± 0.051	0.131LysCys: 0.131 ± 0.011	1.305LysAsp: 1.305 ± 0.033	1.104LysGlu: 1.104 ± 0.028	0.67LysPhe: 0.67 ± 0.022	2.127LysGly: 2.127 ± 0.041	0.423LysHis: 0.423 ± 0.017	1.198LysIle: 1.198 ± 0.029	0.77LysLys: 0.77 ± 0.026	2.403LysLeu: 2.403 ± 0.039	0.644LysMet: 0.644 ± 0.02	0.515LysAsn: 0.515 ± 0.018	1.414LysPro: 1.414 ± 0.036	0.653LysGln: 0.653 ± 0.019	1.701LysArg: 1.701 ± 0.035	1.351LysSer: 1.351 ± 0.032	1.549LysThr: 1.549 ± 0.033	1.776LysVal: 1.776 ± 0.032	0.285LysTrp: 0.285 ± 0.014	0.456LysTyr: 0.456 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	15.368LeuAla: 15.368 ± 0.14	1.136LeuCys: 1.136 ± 0.032	6.767LeuAsp: 6.767 ± 0.074	5.348LeuGlu: 5.348 ± 0.064	3.399LeuPhe: 3.399 ± 0.049	9.2LeuGly: 9.2 ± 0.081	2.06LeuHis: 2.06 ± 0.041	4.749LeuIle: 4.749 ± 0.064	2.486LeuLys: 2.486 ± 0.043	10.797LeuLeu: 10.797 ± 0.134	2.667LeuMet: 2.667 ± 0.041	2.318LeuAsn: 2.318 ± 0.036	6.605LeuPro: 6.605 ± 0.079	3.129LeuGln: 3.129 ± 0.048	8.9LeuArg: 8.9 ± 0.092	6.71LeuSer: 6.71 ± 0.066	6.407LeuThr: 6.407 ± 0.066	7.636LeuVal: 7.636 ± 0.077	1.425LeuTrp: 1.425 ± 0.034	1.955LeuTyr: 1.955 ± 0.032	0.0LeuXaa: 0.0 ± 0.0
Met	3.625MetAla: 3.625 ± 0.044	0.167MetCys: 0.167 ± 0.01	1.403MetAsp: 1.403 ± 0.031	1.248MetGlu: 1.248 ± 0.026	0.736MetPhe: 0.736 ± 0.02	2.266MetGly: 2.266 ± 0.041	0.355MetHis: 0.355 ± 0.016	1.416MetIle: 1.416 ± 0.032	0.819MetLys: 0.819 ± 0.022	2.635MetLeu: 2.635 ± 0.038	0.723MetMet: 0.723 ± 0.022	0.651MetAsn: 0.651 ± 0.02	1.514MetPro: 1.514 ± 0.028	0.86MetGln: 0.86 ± 0.024	1.908MetArg: 1.908 ± 0.035	1.568MetSer: 1.568 ± 0.034	2.329MetThr: 2.329 ± 0.032	1.865MetVal: 1.865 ± 0.033	0.207MetTrp: 0.207 ± 0.013	0.305MetTyr: 0.305 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.652AsnAla: 2.652 ± 0.042	0.201AsnCys: 0.201 ± 0.011	1.192AsnAsp: 1.192 ± 0.035	0.932AsnGlu: 0.932 ± 0.028	0.774AsnPhe: 0.774 ± 0.025	1.952AsnGly: 1.952 ± 0.041	0.422AsnHis: 0.422 ± 0.016	1.098AsnIle: 1.098 ± 0.026	0.457AsnLys: 0.457 ± 0.018	2.246AsnLeu: 2.246 ± 0.041	0.543AsnMet: 0.543 ± 0.018	0.503AsnAsn: 0.503 ± 0.018	1.587AsnPro: 1.587 ± 0.03	0.565AsnGln: 0.565 ± 0.018	1.57AsnArg: 1.57 ± 0.031	0.974AsnSer: 0.974 ± 0.025	1.076AsnThr: 1.076 ± 0.027	1.538AsnVal: 1.538 ± 0.035	0.345AsnTrp: 0.345 ± 0.015	0.509AsnTyr: 0.509 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	7.034ProAla: 7.034 ± 0.085	0.409ProCys: 0.409 ± 0.015	4.251ProAsp: 4.251 ± 0.058	4.656ProGlu: 4.656 ± 0.057	1.93ProPhe: 1.93 ± 0.037	5.23ProGly: 5.23 ± 0.064	1.157ProHis: 1.157 ± 0.027	1.846ProIle: 1.846 ± 0.032	1.31ProLys: 1.31 ± 0.028	5.407ProLeu: 5.407 ± 0.061	1.304ProMet: 1.304 ± 0.029	1.054ProAsn: 1.054 ± 0.027	2.811ProPro: 2.811 ± 0.053	2.151ProGln: 2.151 ± 0.034	3.492ProArg: 3.492 ± 0.061	2.409ProSer: 2.409 ± 0.037	2.166ProThr: 2.166 ± 0.029	4.672ProVal: 4.672 ± 0.057	0.702ProTrp: 0.702 ± 0.021	1.102ProTyr: 1.102 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	4.538GlnAla: 4.538 ± 0.057	0.193GlnCys: 0.193 ± 0.01	1.928GlnAsp: 1.928 ± 0.033	1.527GlnGlu: 1.527 ± 0.037	0.96GlnPhe: 0.96 ± 0.024	2.969GlnGly: 2.969 ± 0.05	0.608GlnHis: 0.608 ± 0.019	2.096GlnIle: 2.096 ± 0.037	0.925GlnLys: 0.925 ± 0.023	2.908GlnLeu: 2.908 ± 0.042	1.088GlnMet: 1.088 ± 0.027	0.779GlnAsn: 0.779 ± 0.022	1.757GlnPro: 1.757 ± 0.035	1.296GlnGln: 1.296 ± 0.032	2.36GlnArg: 2.36 ± 0.041	1.675GlnSer: 1.675 ± 0.03	1.839GlnThr: 1.839 ± 0.036	2.586GlnVal: 2.586 ± 0.042	0.347GlnTrp: 0.347 ± 0.015	0.527GlnTyr: 0.527 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	9.807ArgAla: 9.807 ± 0.079	0.558ArgCys: 0.558 ± 0.019	4.834ArgAsp: 4.834 ± 0.056	3.825ArgGlu: 3.825 ± 0.056	2.809ArgPhe: 2.809 ± 0.037	5.45ArgGly: 5.45 ± 0.06	1.916ArgHis: 1.916 ± 0.042	4.058ArgIle: 4.058 ± 0.049	1.875ArgLys: 1.875 ± 0.035	8.743ArgLeu: 8.743 ± 0.092	2.123ArgMet: 2.123 ± 0.032	1.656ArgAsn: 1.656 ± 0.03	3.867ArgPro: 3.867 ± 0.048	2.667ArgGln: 2.667 ± 0.047	6.268ArgArg: 6.268 ± 0.072	3.627ArgSer: 3.627 ± 0.049	3.13ArgThr: 3.13 ± 0.045	5.029ArgVal: 5.029 ± 0.061	1.032ArgTrp: 1.032 ± 0.03	1.543ArgTyr: 1.543 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	5.875SerAla: 5.875 ± 0.06	0.425SerCys: 0.425 ± 0.019	3.051SerAsp: 3.051 ± 0.05	2.603SerGlu: 2.603 ± 0.039	2.21SerPhe: 2.21 ± 0.037	5.502SerGly: 5.502 ± 0.06	1.021SerHis: 1.021 ± 0.022	2.076SerIle: 2.076 ± 0.039	1.139SerLys: 1.139 ± 0.028	5.048SerLeu: 5.048 ± 0.054	1.245SerMet: 1.245 ± 0.03	1.078SerAsn: 1.078 ± 0.029	2.651SerPro: 2.651 ± 0.041	1.456SerGln: 1.456 ± 0.025	3.545SerArg: 3.545 ± 0.047	2.441SerSer: 2.441 ± 0.041	2.35SerThr: 2.35 ± 0.035	3.658SerVal: 3.658 ± 0.045	0.748SerTrp: 0.748 ± 0.022	1.298SerTyr: 1.298 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	6.501ThrAla: 6.501 ± 0.059	0.466ThrCys: 0.466 ± 0.02	2.992ThrAsp: 2.992 ± 0.049	3.115ThrGlu: 3.115 ± 0.043	1.731ThrPhe: 1.731 ± 0.035	5.656ThrGly: 5.656 ± 0.062	1.113ThrHis: 1.113 ± 0.024	2.248ThrIle: 2.248 ± 0.035	1.116ThrLys: 1.116 ± 0.029	6.468ThrLeu: 6.468 ± 0.076	1.144ThrMet: 1.144 ± 0.028	1.076ThrAsn: 1.076 ± 0.023	3.644ThrPro: 3.644 ± 0.053	1.517ThrGln: 1.517 ± 0.029	3.834ThrArg: 3.834 ± 0.052	2.554ThrSer: 2.554 ± 0.041	2.713ThrThr: 2.713 ± 0.052	4.071ThrVal: 4.071 ± 0.052	0.653ThrTrp: 0.653 ± 0.02	1.111ThrTyr: 1.111 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	9.432ValAla: 9.432 ± 0.08	0.616ValCys: 0.616 ± 0.02	3.82ValAsp: 3.82 ± 0.053	4.101ValGlu: 4.101 ± 0.051	2.71ValPhe: 2.71 ± 0.051	5.066ValGly: 5.066 ± 0.065	1.267ValHis: 1.267 ± 0.024	3.898ValIle: 3.898 ± 0.056	1.697ValLys: 1.697 ± 0.038	8.322ValLeu: 8.322 ± 0.078	2.153ValMet: 2.153 ± 0.035	1.688ValAsn: 1.688 ± 0.032	3.823ValPro: 3.823 ± 0.05	2.154ValGln: 2.154 ± 0.04	4.379ValArg: 4.379 ± 0.056	4.006ValSer: 4.006 ± 0.047	5.107ValThr: 5.107 ± 0.07	5.589ValVal: 5.589 ± 0.068	1.002ValTrp: 1.002 ± 0.026	1.415ValTyr: 1.415 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.383TrpAla: 1.383 ± 0.032	0.141TrpCys: 0.141 ± 0.009	0.747TrpAsp: 0.747 ± 0.021	0.582TrpGlu: 0.582 ± 0.019	0.498TrpPhe: 0.498 ± 0.019	1.064TrpGly: 1.064 ± 0.028	0.35TrpHis: 0.35 ± 0.014	0.686TrpIle: 0.686 ± 0.022	0.384TrpLys: 0.384 ± 0.016	1.742TrpLeu: 1.742 ± 0.036	0.38TrpMet: 0.38 ± 0.016	0.378TrpAsn: 0.378 ± 0.016	0.757TrpPro: 0.757 ± 0.02	0.716TrpGln: 0.716 ± 0.022	1.204TrpArg: 1.204 ± 0.029	0.821TrpSer: 0.821 ± 0.024	0.835TrpThr: 0.835 ± 0.025	0.819TrpVal: 0.819 ± 0.023	0.203TrpTrp: 0.203 ± 0.012	0.253TrpTyr: 0.253 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.535TyrAla: 2.535 ± 0.034	0.201TyrCys: 0.201 ± 0.01	1.507TyrAsp: 1.507 ± 0.026	1.128TyrGlu: 1.128 ± 0.03	0.755TyrPhe: 0.755 ± 0.021	2.012TyrGly: 2.012 ± 0.037	0.484TyrHis: 0.484 ± 0.018	0.757TyrIle: 0.757 ± 0.02	0.402TyrLys: 0.402 ± 0.015	2.231TyrLeu: 2.231 ± 0.036	0.405TyrMet: 0.405 ± 0.014	0.481TyrAsn: 0.481 ± 0.017	1.03TyrPro: 1.03 ± 0.025	0.587TyrGln: 0.587 ± 0.019	1.508TyrArg: 1.508 ± 0.028	1.021TyrSer: 1.021 ± 0.023	1.021TyrThr: 1.021 ± 0.026	1.439TyrVal: 1.439 ± 0.029	0.333TyrTrp: 0.333 ± 0.014	0.498TyrTyr: 0.498 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5375 proteins (1678086 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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