Amino acid dipepetide frequency for Wenling crustacean virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.956AlaAla: 3.956 ± 1.72
0.396AlaCys: 0.396 ± 0.227
1.582AlaAsp: 1.582 ± 1.087
3.956AlaGlu: 3.956 ± 0.938
1.187AlaPhe: 1.187 ± 0.016
5.142AlaGly: 5.142 ± 1.04
0.791AlaHis: 0.791 ± 0.211
4.747AlaIle: 4.747 ± 0.602
4.351AlaLys: 4.351 ± 0.164
5.142AlaLeu: 5.142 ± 0.375
2.373AlaMet: 2.373 ± 0.633
3.956AlaAsn: 3.956 ± 0.274
3.165AlaPro: 3.165 ± 0.18
3.956AlaGln: 3.956 ± 0.391
1.582AlaArg: 1.582 ± 0.422
5.934AlaSer: 5.934 ± 0.078
4.351AlaThr: 4.351 ± 1.165
3.56AlaVal: 3.56 ± 0.047
0.0AlaTrp: 0.0 ± 0.0
2.769AlaTyr: 2.769 ± 0.923
0.0AlaXaa: 0.0 ± 0.0
Cys
0.396CysAla: 0.396 ± 0.438
0.0CysCys: 0.0 ± 0.0
0.396CysAsp: 0.396 ± 0.227
0.791CysGlu: 0.791 ± 0.454
1.187CysPhe: 1.187 ± 0.68
1.187CysGly: 1.187 ± 0.016
0.396CysHis: 0.396 ± 0.227
0.0CysIle: 0.0 ± 0.0
1.187CysLys: 1.187 ± 0.68
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.187CysAsn: 1.187 ± 0.016
0.791CysPro: 0.791 ± 0.454
0.396CysGln: 0.396 ± 0.227
0.0CysArg: 0.0 ± 0.0
0.791CysSer: 0.791 ± 0.876
0.396CysThr: 0.396 ± 0.227
1.582CysVal: 1.582 ± 0.242
0.0CysTrp: 0.0 ± 0.0
0.791CysTyr: 0.791 ± 0.454
0.0CysXaa: 0.0 ± 0.0
Asp
1.978AspAla: 1.978 ± 0.86
0.396AspCys: 0.396 ± 0.227
2.769AspAsp: 2.769 ± 0.407
2.373AspGlu: 2.373 ± 0.031
4.747AspPhe: 4.747 ± 1.392
3.165AspGly: 3.165 ± 0.18
0.791AspHis: 0.791 ± 0.211
4.747AspIle: 4.747 ± 0.063
3.56AspLys: 3.56 ± 0.047
3.56AspLeu: 3.56 ± 0.047
0.791AspMet: 0.791 ± 0.211
4.747AspAsn: 4.747 ± 1.267
1.978AspPro: 1.978 ± 1.134
1.582AspGln: 1.582 ± 0.242
0.791AspArg: 0.791 ± 0.211
2.769AspSer: 2.769 ± 0.407
4.747AspThr: 4.747 ± 2.596
3.56AspVal: 3.56 ± 1.282
1.187AspTrp: 1.187 ± 0.68
2.373AspTyr: 2.373 ± 0.031
0.0AspXaa: 0.0 ± 0.0
Glu
5.142GluAla: 5.142 ± 0.954
0.0GluCys: 0.0 ± 0.0
0.791GluAsp: 0.791 ± 0.454
5.934GluGlu: 5.934 ± 3.401
1.978GluPhe: 1.978 ± 0.469
1.187GluGly: 1.187 ± 0.016
2.373GluHis: 2.373 ± 1.361
4.747GluIle: 4.747 ± 1.267
5.142GluLys: 5.142 ± 0.954
4.747GluLeu: 4.747 ± 0.063
2.373GluMet: 2.373 ± 0.696
3.165GluAsn: 3.165 ± 0.485
1.187GluPro: 1.187 ± 0.649
1.187GluGln: 1.187 ± 0.68
2.769GluArg: 2.769 ± 0.923
3.956GluSer: 3.956 ± 0.391
6.725GluThr: 6.725 ± 1.462
3.56GluVal: 3.56 ± 0.712
1.187GluTrp: 1.187 ± 0.68
3.956GluTyr: 3.956 ± 1.603
0.0GluXaa: 0.0 ± 0.0
Phe
3.956PheAla: 3.956 ± 0.938
0.396PheCys: 0.396 ± 0.227
1.978PheAsp: 1.978 ± 0.469
4.747PheGlu: 4.747 ± 0.602
1.187PhePhe: 1.187 ± 0.016
2.769PheGly: 2.769 ± 0.407
1.582PheHis: 1.582 ± 0.422
2.373PheIle: 2.373 ± 0.696
1.978PheLys: 1.978 ± 0.469
3.165PheLeu: 3.165 ± 1.149
1.187PheMet: 1.187 ± 0.016
1.582PheAsn: 1.582 ± 0.242
0.791PhePro: 0.791 ± 0.211
1.582PheGln: 1.582 ± 0.422
1.978PheArg: 1.978 ± 0.195
4.351PheSer: 4.351 ± 1.493
3.165PheThr: 3.165 ± 0.844
2.769PheVal: 2.769 ± 0.258
0.396PheTrp: 0.396 ± 0.227
1.978PheTyr: 1.978 ± 0.195
0.0PheXaa: 0.0 ± 0.0
Gly
1.582GlyAla: 1.582 ± 1.087
0.791GlyCys: 0.791 ± 0.211
6.329GlyAsp: 6.329 ± 1.634
4.351GlyGlu: 4.351 ± 0.5
3.56GlyPhe: 3.56 ± 0.047
1.582GlyGly: 1.582 ± 0.422
0.791GlyHis: 0.791 ± 0.211
2.769GlyIle: 2.769 ± 0.258
2.769GlyLys: 2.769 ± 0.258
3.165GlyLeu: 3.165 ± 1.149
1.978GlyMet: 1.978 ± 0.86
3.956GlyAsn: 3.956 ± 0.274
0.396GlyPro: 0.396 ± 0.227
1.187GlyGln: 1.187 ± 0.649
1.978GlyArg: 1.978 ± 0.86
1.978GlySer: 1.978 ± 0.195
5.934GlyThr: 5.934 ± 4.574
3.956GlyVal: 3.956 ± 0.391
0.396GlyTrp: 0.396 ± 0.438
3.165GlyTyr: 3.165 ± 1.149
0.0GlyXaa: 0.0 ± 0.0
His
1.187HisAla: 1.187 ± 0.016
0.0HisCys: 0.0 ± 0.0
0.791HisAsp: 0.791 ± 0.211
1.187HisGlu: 1.187 ± 0.016
1.582HisPhe: 1.582 ± 0.422
1.582HisGly: 1.582 ± 0.422
0.791HisHis: 0.791 ± 0.454
1.187HisIle: 1.187 ± 0.68
0.396HisLys: 0.396 ± 0.227
1.582HisLeu: 1.582 ± 0.907
0.396HisMet: 0.396 ± 0.227
0.396HisAsn: 0.396 ± 0.438
0.791HisPro: 0.791 ± 0.211
1.187HisGln: 1.187 ± 0.68
1.582HisArg: 1.582 ± 0.907
1.582HisSer: 1.582 ± 0.907
1.582HisThr: 1.582 ± 0.242
1.978HisVal: 1.978 ± 0.469
0.396HisTrp: 0.396 ± 0.438
0.396HisTyr: 0.396 ± 0.438
0.0HisXaa: 0.0 ± 0.0
Ile
5.538IleAla: 5.538 ± 0.516
0.396IleCys: 0.396 ± 0.227
4.747IleAsp: 4.747 ± 2.596
3.956IleGlu: 3.956 ± 0.274
2.373IlePhe: 2.373 ± 1.361
3.56IleGly: 3.56 ± 0.618
1.582IleHis: 1.582 ± 0.242
5.538IleIle: 5.538 ± 1.181
3.56IleLys: 3.56 ± 0.712
7.12IleLeu: 7.12 ± 2.088
1.187IleMet: 1.187 ± 0.016
7.12IleAsn: 7.12 ± 1.423
3.56IlePro: 3.56 ± 2.612
3.56IleGln: 3.56 ± 0.712
2.769IleArg: 2.769 ± 0.258
3.956IleSer: 3.956 ± 0.274
3.165IleThr: 3.165 ± 0.18
3.956IleVal: 3.956 ± 0.391
1.187IleTrp: 1.187 ± 0.016
2.769IleTyr: 2.769 ± 0.258
0.0IleXaa: 0.0 ± 0.0
Lys
5.538LysAla: 5.538 ± 0.516
0.396LysCys: 0.396 ± 0.227
3.56LysAsp: 3.56 ± 0.712
3.956LysGlu: 3.956 ± 2.268
2.769LysPhe: 2.769 ± 0.923
3.165LysGly: 3.165 ± 1.149
0.791LysHis: 0.791 ± 0.454
2.373LysIle: 2.373 ± 1.361
2.373LysLys: 2.373 ± 1.361
5.538LysLeu: 5.538 ± 1.181
1.187LysMet: 1.187 ± 0.68
3.56LysAsn: 3.56 ± 1.376
2.373LysPro: 2.373 ± 1.298
3.56LysGln: 3.56 ± 0.047
4.747LysArg: 4.747 ± 0.602
6.725LysSer: 6.725 ± 0.532
4.351LysThr: 4.351 ± 1.83
5.934LysVal: 5.934 ± 0.078
0.791LysTrp: 0.791 ± 0.211
2.769LysTyr: 2.769 ± 0.407
0.0LysXaa: 0.0 ± 0.0
Leu
5.934LeuAla: 5.934 ± 0.586
1.187LeuCys: 1.187 ± 0.68
3.56LeuAsp: 3.56 ± 0.047
3.56LeuGlu: 3.56 ± 0.712
2.769LeuPhe: 2.769 ± 0.407
3.165LeuGly: 3.165 ± 0.485
1.582LeuHis: 1.582 ± 0.907
7.911LeuIle: 7.911 ± 0.117
8.307LeuLys: 8.307 ± 2.103
7.12LeuLeu: 7.12 ± 2.088
1.978LeuMet: 1.978 ± 0.86
4.351LeuAsn: 4.351 ± 0.164
3.956LeuPro: 3.956 ± 0.938
1.582LeuGln: 1.582 ± 0.422
4.351LeuArg: 4.351 ± 1.83
7.12LeuSer: 7.12 ± 0.094
5.538LeuThr: 5.538 ± 1.181
5.142LeuVal: 5.142 ± 2.369
0.396LeuTrp: 0.396 ± 0.227
2.373LeuTyr: 2.373 ± 0.031
0.0LeuXaa: 0.0 ± 0.0
Met
1.978MetAla: 1.978 ± 1.134
0.396MetCys: 0.396 ± 0.227
1.187MetAsp: 1.187 ± 0.68
0.791MetGlu: 0.791 ± 0.454
0.396MetPhe: 0.396 ± 0.438
1.187MetGly: 1.187 ± 0.649
1.187MetHis: 1.187 ± 0.68
1.582MetIle: 1.582 ± 0.242
3.165MetLys: 3.165 ± 0.485
1.978MetLeu: 1.978 ± 0.469
1.187MetMet: 1.187 ± 0.68
1.187MetAsn: 1.187 ± 0.68
1.187MetPro: 1.187 ± 0.649
0.396MetGln: 0.396 ± 0.438
3.165MetArg: 3.165 ± 0.844
1.978MetSer: 1.978 ± 1.525
1.582MetThr: 1.582 ± 0.422
0.0MetVal: 0.0 ± 0.0
0.396MetTrp: 0.396 ± 0.438
0.791MetTyr: 0.791 ± 0.211
0.0MetXaa: 0.0 ± 0.0
Asn
4.351AsnAla: 4.351 ± 0.164
0.396AsnCys: 0.396 ± 0.227
3.56AsnAsp: 3.56 ± 0.712
4.351AsnGlu: 4.351 ± 1.165
1.582AsnPhe: 1.582 ± 0.422
2.373AsnGly: 2.373 ± 1.298
0.791AsnHis: 0.791 ± 0.454
6.329AsnIle: 6.329 ± 0.305
4.747AsnLys: 4.747 ± 1.392
5.142AsnLeu: 5.142 ± 1.04
1.978AsnMet: 1.978 ± 0.594
1.978AsnAsn: 1.978 ± 0.195
2.769AsnPro: 2.769 ± 0.258
3.165AsnGln: 3.165 ± 1.149
3.956AsnArg: 3.956 ± 0.391
2.373AsnSer: 2.373 ± 0.696
5.142AsnThr: 5.142 ± 0.375
5.538AsnVal: 5.538 ± 0.516
1.582AsnTrp: 1.582 ± 0.422
2.373AsnTyr: 2.373 ± 0.633
0.0AsnXaa: 0.0 ± 0.0
Pro
1.187ProAla: 1.187 ± 0.016
0.396ProCys: 0.396 ± 0.438
2.373ProAsp: 2.373 ± 0.633
1.978ProGlu: 1.978 ± 0.86
2.373ProPhe: 2.373 ± 0.633
2.373ProGly: 2.373 ± 0.633
1.187ProHis: 1.187 ± 0.649
4.747ProIle: 4.747 ± 1.267
1.978ProLys: 1.978 ± 0.195
3.956ProLeu: 3.956 ± 0.391
1.187ProMet: 1.187 ± 0.016
2.769ProAsn: 2.769 ± 0.407
0.791ProPro: 0.791 ± 0.876
0.791ProGln: 0.791 ± 0.211
0.396ProArg: 0.396 ± 0.227
3.165ProSer: 3.165 ± 0.18
1.582ProThr: 1.582 ± 1.087
3.956ProVal: 3.956 ± 1.056
0.0ProTrp: 0.0 ± 0.0
3.165ProTyr: 3.165 ± 0.18
0.0ProXaa: 0.0 ± 0.0
Gln
1.187GlnAla: 1.187 ± 0.68
1.582GlnCys: 1.582 ± 0.242
1.582GlnAsp: 1.582 ± 1.087
1.582GlnGlu: 1.582 ± 0.907
3.165GlnPhe: 3.165 ± 0.485
1.978GlnGly: 1.978 ± 0.195
0.396GlnHis: 0.396 ± 0.227
3.165GlnIle: 3.165 ± 0.485
2.769GlnLys: 2.769 ± 1.587
2.769GlnLeu: 2.769 ± 0.407
1.187GlnMet: 1.187 ± 0.016
2.373GlnAsn: 2.373 ± 0.696
1.582GlnPro: 1.582 ± 0.422
1.978GlnGln: 1.978 ± 1.134
0.0GlnArg: 0.0 ± 0.0
4.747GlnSer: 4.747 ± 1.931
1.582GlnThr: 1.582 ± 0.907
3.56GlnVal: 3.56 ± 0.712
0.0GlnTrp: 0.0 ± 0.0
1.187GlnTyr: 1.187 ± 0.68
0.0GlnXaa: 0.0 ± 0.0
Arg
1.978ArgAla: 1.978 ± 0.86
1.187ArgCys: 1.187 ± 0.016
1.978ArgAsp: 1.978 ± 0.469
1.582ArgGlu: 1.582 ± 0.242
1.187ArgPhe: 1.187 ± 0.649
1.978ArgGly: 1.978 ± 0.195
0.396ArgHis: 0.396 ± 0.227
2.373ArgIle: 2.373 ± 0.031
1.978ArgLys: 1.978 ± 1.134
0.791ArgLeu: 0.791 ± 0.211
1.187ArgMet: 1.187 ± 0.446
3.56ArgAsn: 3.56 ± 1.376
2.769ArgPro: 2.769 ± 1.071
1.978ArgGln: 1.978 ± 0.469
1.187ArgArg: 1.187 ± 0.016
2.769ArgSer: 2.769 ± 0.923
3.56ArgThr: 3.56 ± 0.712
5.142ArgVal: 5.142 ± 1.04
0.0ArgTrp: 0.0 ± 0.0
2.373ArgTyr: 2.373 ± 0.633
0.0ArgXaa: 0.0 ± 0.0
Ser
3.165SerAla: 3.165 ± 1.149
1.582SerCys: 1.582 ± 0.907
5.142SerAsp: 5.142 ± 3.034
4.351SerGlu: 4.351 ± 1.165
2.373SerPhe: 2.373 ± 0.633
6.725SerGly: 6.725 ± 1.462
0.791SerHis: 0.791 ± 0.876
4.747SerIle: 4.747 ± 0.602
3.56SerLys: 3.56 ± 0.712
7.516SerLeu: 7.516 ± 1.009
1.187SerMet: 1.187 ± 0.016
3.56SerAsn: 3.56 ± 0.618
3.56SerPro: 3.56 ± 1.282
3.956SerGln: 3.956 ± 1.603
3.165SerArg: 3.165 ± 0.485
4.747SerSer: 4.747 ± 0.602
5.142SerThr: 5.142 ± 2.369
3.956SerVal: 3.956 ± 1.056
0.791SerTrp: 0.791 ± 0.876
2.373SerTyr: 2.373 ± 1.963
0.0SerXaa: 0.0 ± 0.0
Thr
5.538ThrAla: 5.538 ± 0.813
0.0ThrCys: 0.0 ± 0.0
2.769ThrAsp: 2.769 ± 0.407
3.956ThrGlu: 3.956 ± 0.938
4.747ThrPhe: 4.747 ± 2.596
1.978ThrGly: 1.978 ± 0.469
1.582ThrHis: 1.582 ± 0.242
4.351ThrIle: 4.351 ± 0.5
5.142ThrLys: 5.142 ± 1.04
7.911ThrLeu: 7.911 ± 2.111
1.187ThrMet: 1.187 ± 0.016
6.725ThrAsn: 6.725 ± 0.798
2.769ThrPro: 2.769 ± 2.4
2.769ThrGln: 2.769 ± 0.258
1.978ThrArg: 1.978 ± 0.469
4.747ThrSer: 4.747 ± 1.931
1.978ThrThr: 1.978 ± 0.195
5.142ThrVal: 5.142 ± 0.289
0.0ThrTrp: 0.0 ± 0.0
3.165ThrTyr: 3.165 ± 0.18
0.0ThrXaa: 0.0 ± 0.0
Val
5.934ValAla: 5.934 ± 1.251
1.978ValCys: 1.978 ± 0.195
4.351ValAsp: 4.351 ± 0.5
6.725ValGlu: 6.725 ± 0.798
2.769ValPhe: 2.769 ± 0.923
4.747ValGly: 4.747 ± 0.727
0.791ValHis: 0.791 ± 0.211
3.56ValIle: 3.56 ± 0.712
3.56ValLys: 3.56 ± 0.712
5.142ValLeu: 5.142 ± 0.954
1.582ValMet: 1.582 ± 0.422
5.538ValAsn: 5.538 ± 0.813
3.956ValPro: 3.956 ± 0.391
1.582ValGln: 1.582 ± 0.422
1.582ValArg: 1.582 ± 0.422
5.538ValSer: 5.538 ± 2.807
5.538ValThr: 5.538 ± 0.813
6.329ValVal: 6.329 ± 1.689
0.0ValTrp: 0.0 ± 0.0
1.582ValTyr: 1.582 ± 0.242
0.0ValXaa: 0.0 ± 0.0
Trp
0.396TrpAla: 0.396 ± 0.438
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.396TrpPhe: 0.396 ± 0.438
0.396TrpGly: 0.396 ± 0.227
0.396TrpHis: 0.396 ± 0.227
1.187TrpIle: 1.187 ± 0.016
0.791TrpLys: 0.791 ± 0.211
0.791TrpLeu: 0.791 ± 0.454
0.396TrpMet: 0.396 ± 0.227
0.396TrpAsn: 0.396 ± 0.438
0.0TrpPro: 0.0 ± 0.0
0.396TrpGln: 0.396 ± 0.227
1.187TrpArg: 1.187 ± 0.649
0.791TrpSer: 0.791 ± 0.876
0.0TrpThr: 0.0 ± 0.0
0.396TrpVal: 0.396 ± 0.227
0.0TrpTrp: 0.0 ± 0.0
0.791TrpTyr: 0.791 ± 0.454
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.978TyrAla: 1.978 ± 0.86
0.0TyrCys: 0.0 ± 0.0
3.165TyrAsp: 3.165 ± 0.18
1.978TyrGlu: 1.978 ± 1.525
1.582TyrPhe: 1.582 ± 0.242
2.373TyrGly: 2.373 ± 0.031
1.582TyrHis: 1.582 ± 0.242
3.165TyrIle: 3.165 ± 0.485
5.142TyrLys: 5.142 ± 0.954
4.747TyrLeu: 4.747 ± 1.392
0.791TyrMet: 0.791 ± 0.454
2.769TyrAsn: 2.769 ± 0.923
1.978TyrPro: 1.978 ± 0.195
1.582TyrGln: 1.582 ± 0.242
0.791TyrArg: 0.791 ± 0.211
2.373TyrSer: 2.373 ± 0.633
2.373TyrThr: 2.373 ± 0.633
2.769TyrVal: 2.769 ± 0.258
0.0TyrTrp: 0.0 ± 0.0
1.582TyrTyr: 1.582 ± 0.907
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2529 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski