Amino acid dipepetide frequency for Beet mild yellowing virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.934AlaAla: 3.934 ± 0.735
1.574AlaCys: 1.574 ± 0.928
3.147AlaAsp: 3.147 ± 1.708
6.294AlaGlu: 6.294 ± 1.802
3.147AlaPhe: 3.147 ± 1.618
6.294AlaGly: 6.294 ± 1.693
0.0AlaHis: 0.0 ± 0.0
1.574AlaIle: 1.574 ± 0.716
2.36AlaLys: 2.36 ± 0.828
7.868AlaLeu: 7.868 ± 1.406
1.574AlaMet: 1.574 ± 0.85
0.787AlaAsn: 0.787 ± 0.915
3.147AlaPro: 3.147 ± 1.857
1.574AlaGln: 1.574 ± 0.716
7.081AlaArg: 7.081 ± 1.868
7.868AlaSer: 7.868 ± 2.749
7.081AlaThr: 7.081 ± 2.408
2.36AlaVal: 2.36 ± 0.811
0.0AlaTrp: 0.0 ± 0.0
2.36AlaTyr: 2.36 ± 1.968
0.0AlaXaa: 0.0 ± 0.0
Cys
0.787CysAla: 0.787 ± 0.915
0.787CysCys: 0.787 ± 0.464
0.0CysAsp: 0.0 ± 0.0
0.787CysGlu: 0.787 ± 0.464
0.0CysPhe: 0.0 ± 0.0
1.574CysGly: 1.574 ± 0.73
0.0CysHis: 0.0 ± 0.0
2.36CysIle: 2.36 ± 0.811
1.574CysLys: 1.574 ± 0.716
0.787CysLeu: 0.787 ± 0.464
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
2.36CysPro: 2.36 ± 0.828
0.787CysGln: 0.787 ± 0.878
0.0CysArg: 0.0 ± 0.0
3.147CysSer: 3.147 ± 1.555
0.787CysThr: 0.787 ± 0.464
1.574CysVal: 1.574 ± 0.73
0.0CysTrp: 0.0 ± 0.0
0.787CysTyr: 0.787 ± 0.464
0.0CysXaa: 0.0 ± 0.0
Asp
3.147AspAla: 3.147 ± 1.314
0.787AspCys: 0.787 ± 0.878
3.147AspAsp: 3.147 ± 2.632
1.574AspGlu: 1.574 ± 0.85
3.147AspPhe: 3.147 ± 1.102
3.147AspGly: 3.147 ± 1.136
1.574AspHis: 1.574 ± 1.182
0.787AspIle: 0.787 ± 0.915
0.787AspLys: 0.787 ± 0.464
3.147AspLeu: 3.147 ± 1.555
0.787AspMet: 0.787 ± 0.915
0.787AspAsn: 0.787 ± 0.878
2.36AspPro: 2.36 ± 0.897
2.36AspGln: 2.36 ± 0.828
0.0AspArg: 0.0 ± 0.0
0.0AspSer: 0.0 ± 0.0
0.787AspThr: 0.787 ± 0.464
2.36AspVal: 2.36 ± 0.897
1.574AspTrp: 1.574 ± 0.716
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.721GluAla: 4.721 ± 1.212
1.574GluCys: 1.574 ± 0.85
1.574GluAsp: 1.574 ± 0.85
6.294GluGlu: 6.294 ± 3.087
3.147GluPhe: 3.147 ± 0.676
2.36GluGly: 2.36 ± 1.393
0.0GluHis: 0.0 ± 0.0
4.721GluIle: 4.721 ± 1.903
2.36GluLys: 2.36 ± 1.393
5.507GluLeu: 5.507 ± 2.07
0.787GluMet: 0.787 ± 0.915
3.147GluAsn: 3.147 ± 2.488
2.36GluPro: 2.36 ± 1.393
1.574GluGln: 1.574 ± 1.861
4.721GluArg: 4.721 ± 2.189
3.934GluSer: 3.934 ± 1.471
3.147GluThr: 3.147 ± 1.136
1.574GluVal: 1.574 ± 0.85
1.574GluTrp: 1.574 ± 0.928
0.787GluTyr: 0.787 ± 0.878
0.0GluXaa: 0.0 ± 0.0
Phe
3.934PheAla: 3.934 ± 1.477
0.787PheCys: 0.787 ± 0.915
0.787PheAsp: 0.787 ± 0.464
3.147PheGlu: 3.147 ± 1.459
1.574PhePhe: 1.574 ± 0.928
3.147PheGly: 3.147 ± 1.618
2.36PheHis: 2.36 ± 1.024
3.147PheIle: 3.147 ± 2.488
0.787PheLys: 0.787 ± 0.915
3.934PheLeu: 3.934 ± 1.29
0.0PheMet: 0.0 ± 0.0
0.787PheAsn: 0.787 ± 0.464
1.574PhePro: 1.574 ± 0.73
1.574PheGln: 1.574 ± 0.73
2.36PheArg: 2.36 ± 1.533
5.507PheSer: 5.507 ± 0.456
4.721PheThr: 4.721 ± 1.903
2.36PheVal: 2.36 ± 1.533
1.574PheTrp: 1.574 ± 1.182
2.36PheTyr: 2.36 ± 1.589
0.0PheXaa: 0.0 ± 0.0
Gly
4.721GlyAla: 4.721 ± 1.187
0.0GlyCys: 0.0 ± 0.0
0.787GlyAsp: 0.787 ± 0.464
4.721GlyGlu: 4.721 ± 2.189
0.787GlyPhe: 0.787 ± 0.464
2.36GlyGly: 2.36 ± 1.005
1.574GlyHis: 1.574 ± 0.85
0.787GlyIle: 0.787 ± 0.878
7.081GlyLys: 7.081 ± 1.719
2.36GlyLeu: 2.36 ± 1.393
2.36GlyMet: 2.36 ± 1.474
4.721GlyAsn: 4.721 ± 1.657
2.36GlyPro: 2.36 ± 0.828
2.36GlyGln: 2.36 ± 1.72
8.655GlyArg: 8.655 ± 1.68
8.655GlySer: 8.655 ± 3.775
4.721GlyThr: 4.721 ± 1.027
2.36GlyVal: 2.36 ± 1.393
0.787GlyTrp: 0.787 ± 0.464
1.574GlyTyr: 1.574 ± 0.928
0.0GlyXaa: 0.0 ± 0.0
His
1.574HisAla: 1.574 ± 0.928
0.787HisCys: 0.787 ± 0.878
2.36HisAsp: 2.36 ± 1.024
2.36HisGlu: 2.36 ± 0.897
0.0HisPhe: 0.0 ± 0.0
0.787HisGly: 0.787 ± 0.464
0.787HisHis: 0.787 ± 0.915
1.574HisIle: 1.574 ± 0.73
0.0HisLys: 0.0 ± 0.0
2.36HisLeu: 2.36 ± 1.899
0.787HisMet: 0.787 ± 0.464
1.574HisAsn: 1.574 ± 1.291
0.0HisPro: 0.0 ± 0.0
0.787HisGln: 0.787 ± 0.93
2.36HisArg: 2.36 ± 1.899
3.147HisSer: 3.147 ± 1.699
0.787HisThr: 0.787 ± 0.93
1.574HisVal: 1.574 ± 0.85
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.36IleAla: 2.36 ± 1.533
0.787IleCys: 0.787 ± 0.915
2.36IleAsp: 2.36 ± 1.589
1.574IleGlu: 1.574 ± 0.928
2.36IlePhe: 2.36 ± 0.811
1.574IleGly: 1.574 ± 0.928
0.0IleHis: 0.0 ± 0.0
0.787IleIle: 0.787 ± 0.915
3.147IleLys: 3.147 ± 1.314
5.507IleLeu: 5.507 ± 1.933
0.787IleMet: 0.787 ± 0.915
2.36IleAsn: 2.36 ± 2.633
3.147IlePro: 3.147 ± 1.314
2.36IleGln: 2.36 ± 0.811
1.574IleArg: 1.574 ± 1.831
3.147IleSer: 3.147 ± 0.929
3.147IleThr: 3.147 ± 2.394
0.787IleVal: 0.787 ± 0.464
1.574IleTrp: 1.574 ± 0.928
1.574IleTyr: 1.574 ± 0.73
0.0IleXaa: 0.0 ± 0.0
Lys
4.721LysAla: 4.721 ± 1.336
2.36LysCys: 2.36 ± 0.828
3.934LysAsp: 3.934 ± 1.341
2.36LysGlu: 2.36 ± 0.811
3.934LysPhe: 3.934 ± 0.735
1.574LysGly: 1.574 ± 0.716
0.787LysHis: 0.787 ± 0.93
3.147LysIle: 3.147 ± 1.018
3.147LysLys: 3.147 ± 1.102
3.147LysLeu: 3.147 ± 0.676
1.574LysMet: 1.574 ± 0.722
1.574LysAsn: 1.574 ± 0.928
3.934LysPro: 3.934 ± 1.053
3.147LysGln: 3.147 ± 1.102
3.147LysArg: 3.147 ± 1.459
7.868LysSer: 7.868 ± 3.885
5.507LysThr: 5.507 ± 1.544
0.787LysVal: 0.787 ± 0.464
0.787LysTrp: 0.787 ± 0.915
1.574LysTyr: 1.574 ± 0.928
0.0LysXaa: 0.0 ± 0.0
Leu
7.868LeuAla: 7.868 ± 3.567
1.574LeuCys: 1.574 ± 0.928
3.934LeuAsp: 3.934 ± 0.573
1.574LeuGlu: 1.574 ± 0.716
4.721LeuPhe: 4.721 ± 1.151
2.36LeuGly: 2.36 ± 0.856
1.574LeuHis: 1.574 ± 1.182
0.787LeuIle: 0.787 ± 0.464
7.868LeuLys: 7.868 ± 2.724
7.081LeuLeu: 7.081 ± 2.893
3.934LeuMet: 3.934 ± 0.967
2.36LeuAsn: 2.36 ± 1.589
6.294LeuPro: 6.294 ± 2.856
3.934LeuGln: 3.934 ± 0.835
3.934LeuArg: 3.934 ± 4.576
10.228LeuSer: 10.228 ± 1.112
9.441LeuThr: 9.441 ± 2.242
6.294LeuVal: 6.294 ± 2.261
1.574LeuTrp: 1.574 ± 0.85
2.36LeuTyr: 2.36 ± 0.897
0.0LeuXaa: 0.0 ± 0.0
Met
0.787MetAla: 0.787 ± 0.464
0.0MetCys: 0.0 ± 0.0
2.36MetAsp: 2.36 ± 1.589
2.36MetGlu: 2.36 ± 1.72
0.0MetPhe: 0.0 ± 0.0
0.787MetGly: 0.787 ± 0.915
0.787MetHis: 0.787 ± 0.464
0.787MetIle: 0.787 ± 0.464
2.36MetLys: 2.36 ± 0.828
1.574MetLeu: 1.574 ± 0.716
0.0MetMet: 0.0 ± 0.0
0.787MetAsn: 0.787 ± 0.878
0.0MetPro: 0.0 ± 0.0
1.574MetGln: 1.574 ± 0.73
0.0MetArg: 0.0 ± 0.0
1.574MetSer: 1.574 ± 0.85
1.574MetThr: 1.574 ± 0.85
2.36MetVal: 2.36 ± 1.474
0.0MetTrp: 0.0 ± 0.0
0.787MetTyr: 0.787 ± 0.915
0.0MetXaa: 0.0 ± 0.0
Asn
3.934AsnAla: 3.934 ± 1.696
1.574AsnCys: 1.574 ± 0.73
0.0AsnAsp: 0.0 ± 0.0
0.787AsnGlu: 0.787 ± 0.915
0.787AsnPhe: 0.787 ± 0.915
7.081AsnGly: 7.081 ± 2.485
0.787AsnHis: 0.787 ± 0.915
0.787AsnIle: 0.787 ± 0.915
3.147AsnLys: 3.147 ± 1.136
1.574AsnLeu: 1.574 ± 0.716
1.574AsnMet: 1.574 ± 0.827
1.574AsnAsn: 1.574 ± 0.716
1.574AsnPro: 1.574 ± 1.291
0.0AsnGln: 0.0 ± 0.0
1.574AsnArg: 1.574 ± 1.259
4.721AsnSer: 4.721 ± 3.15
2.36AsnThr: 2.36 ± 2.018
0.787AsnVal: 0.787 ± 0.464
1.574AsnTrp: 1.574 ± 0.928
3.147AsnTyr: 3.147 ± 1.102
0.0AsnXaa: 0.0 ± 0.0
Pro
4.721ProAla: 4.721 ± 1.63
0.787ProCys: 0.787 ± 0.464
0.0ProAsp: 0.0 ± 0.0
3.147ProGlu: 3.147 ± 1.314
0.787ProPhe: 0.787 ± 0.93
7.081ProGly: 7.081 ± 1.855
0.787ProHis: 0.787 ± 0.878
0.787ProIle: 0.787 ± 0.464
3.147ProLys: 3.147 ± 1.018
6.294ProLeu: 6.294 ± 2.856
0.787ProMet: 0.787 ± 0.464
1.574ProAsn: 1.574 ± 0.928
3.147ProPro: 3.147 ± 1.102
2.36ProGln: 2.36 ± 1.393
8.655ProArg: 8.655 ± 1.218
5.507ProSer: 5.507 ± 0.456
1.574ProThr: 1.574 ± 0.85
2.36ProVal: 2.36 ± 1.024
0.0ProTrp: 0.0 ± 0.0
0.787ProTyr: 0.787 ± 0.464
0.0ProXaa: 0.0 ± 0.0
Gln
3.147GlnAla: 3.147 ± 1.136
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
2.36GlnGlu: 2.36 ± 1.005
2.36GlnPhe: 2.36 ± 1.968
0.787GlnGly: 0.787 ± 0.464
2.36GlnHis: 2.36 ± 1.005
1.574GlnIle: 1.574 ± 0.928
2.36GlnLys: 2.36 ± 0.856
2.36GlnLeu: 2.36 ± 1.589
0.0GlnMet: 0.0 ± 0.0
3.147GlnAsn: 3.147 ± 0.929
1.574GlnPro: 1.574 ± 1.291
0.0GlnGln: 0.0 ± 0.0
4.721GlnArg: 4.721 ± 1.304
3.147GlnSer: 3.147 ± 0.706
1.574GlnThr: 1.574 ± 1.291
1.574GlnVal: 1.574 ± 0.85
1.574GlnTrp: 1.574 ± 1.861
0.787GlnTyr: 0.787 ± 0.464
0.0GlnXaa: 0.0 ± 0.0
Arg
3.934ArgAla: 3.934 ± 1.503
0.0ArgCys: 0.0 ± 0.0
3.147ArgAsp: 3.147 ± 1.459
3.934ArgGlu: 3.934 ± 1.29
2.36ArgPhe: 2.36 ± 1.589
5.507ArgGly: 5.507 ± 1.52
1.574ArgHis: 1.574 ± 1.861
2.36ArgIle: 2.36 ± 1.533
3.934ArgLys: 3.934 ± 1.471
4.721ArgLeu: 4.721 ± 4.503
0.787ArgMet: 0.787 ± 1.122
5.507ArgAsn: 5.507 ± 2.176
3.934ArgPro: 3.934 ± 2.616
2.36ArgGln: 2.36 ± 0.897
14.162ArgArg: 14.162 ± 9.502
7.081ArgSer: 7.081 ± 1.346
4.721ArgThr: 4.721 ± 4.004
3.934ArgVal: 3.934 ± 1.29
0.0ArgTrp: 0.0 ± 0.0
0.0ArgTyr: 0.0 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
3.147SerAla: 3.147 ± 0.929
0.787SerCys: 0.787 ± 0.464
2.36SerAsp: 2.36 ± 0.828
4.721SerGlu: 4.721 ± 1.187
7.081SerPhe: 7.081 ± 1.897
7.868SerGly: 7.868 ± 2.047
1.574SerHis: 1.574 ± 0.73
4.721SerIle: 4.721 ± 1.425
6.294SerLys: 6.294 ± 0.891
11.015SerLeu: 11.015 ± 1.296
1.574SerMet: 1.574 ± 0.716
0.787SerAsn: 0.787 ± 0.464
7.868SerPro: 7.868 ± 2.855
5.507SerGln: 5.507 ± 3.873
5.507SerArg: 5.507 ± 2.294
19.67SerSer: 19.67 ± 5.309
9.441SerThr: 9.441 ± 1.449
6.294SerVal: 6.294 ± 1.968
0.787SerTrp: 0.787 ± 0.93
3.147SerTyr: 3.147 ± 1.136
0.0SerXaa: 0.0 ± 0.0
Thr
7.868ThrAla: 7.868 ± 2.087
1.574ThrCys: 1.574 ± 0.73
0.787ThrAsp: 0.787 ± 0.464
1.574ThrGlu: 1.574 ± 0.73
5.507ThrPhe: 5.507 ± 1.204
4.721ThrGly: 4.721 ± 2.532
1.574ThrHis: 1.574 ± 0.85
5.507ThrIle: 5.507 ± 1.494
3.147ThrLys: 3.147 ± 0.929
7.868ThrLeu: 7.868 ± 2.855
1.574ThrMet: 1.574 ± 1.291
3.934ThrAsn: 3.934 ± 1.29
3.147ThrPro: 3.147 ± 1.102
1.574ThrGln: 1.574 ± 0.716
3.934ThrArg: 3.934 ± 2.444
6.294ThrSer: 6.294 ± 2.791
6.294ThrThr: 6.294 ± 2.105
3.934ThrVal: 3.934 ± 1.503
0.0ThrTrp: 0.0 ± 0.0
3.147ThrTyr: 3.147 ± 1.102
0.0ThrXaa: 0.0 ± 0.0
Val
1.574ValAla: 1.574 ± 0.716
0.787ValCys: 0.787 ± 0.464
0.787ValAsp: 0.787 ± 0.464
2.36ValGlu: 2.36 ± 0.811
1.574ValPhe: 1.574 ± 0.716
2.36ValGly: 2.36 ± 1.024
2.36ValHis: 2.36 ± 0.811
0.787ValIle: 0.787 ± 0.878
3.934ValLys: 3.934 ± 1.484
9.441ValLeu: 9.441 ± 2.55
0.0ValMet: 0.0 ± 0.0
2.36ValAsn: 2.36 ± 1.005
3.934ValPro: 3.934 ± 2.515
0.787ValGln: 0.787 ± 0.878
0.787ValArg: 0.787 ± 0.93
4.721ValSer: 4.721 ± 1.657
2.36ValThr: 2.36 ± 0.811
6.294ValVal: 6.294 ± 2.864
2.36ValTrp: 2.36 ± 0.811
0.787ValTyr: 0.787 ± 0.93
0.0ValXaa: 0.0 ± 0.0
Trp
0.787TrpAla: 0.787 ± 0.464
0.787TrpCys: 0.787 ± 0.915
0.0TrpAsp: 0.0 ± 0.0
0.787TrpGlu: 0.787 ± 0.464
0.787TrpPhe: 0.787 ± 0.915
0.787TrpGly: 0.787 ± 0.464
1.574TrpHis: 1.574 ± 0.716
0.787TrpIle: 0.787 ± 0.464
0.0TrpLys: 0.0 ± 0.0
1.574TrpLeu: 1.574 ± 0.85
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.787TrpPro: 0.787 ± 0.464
0.0TrpGln: 0.0 ± 0.0
1.574TrpArg: 1.574 ± 0.73
3.147TrpSer: 3.147 ± 2.632
1.574TrpThr: 1.574 ± 0.85
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.787TrpTyr: 0.787 ± 0.464
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.36TyrAla: 2.36 ± 0.811
0.787TyrCys: 0.787 ± 0.915
0.787TyrAsp: 0.787 ± 0.464
3.147TyrGlu: 3.147 ± 1.136
2.36TyrPhe: 2.36 ± 1.589
1.574TyrGly: 1.574 ± 0.928
1.574TyrHis: 1.574 ± 1.259
3.147TyrIle: 3.147 ± 1.136
1.574TyrLys: 1.574 ± 1.756
1.574TyrLeu: 1.574 ± 0.73
0.787TyrMet: 0.787 ± 0.464
1.574TyrAsn: 1.574 ± 0.73
0.787TyrPro: 0.787 ± 0.464
0.787TyrGln: 0.787 ± 0.93
0.0TyrArg: 0.0 ± 0.0
0.787TyrSer: 0.787 ± 0.464
2.36TyrThr: 2.36 ± 0.811
0.787TyrVal: 0.787 ± 0.464
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1272 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski