Amino acid dipepetide frequency for Bos taurus papillomavirus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.752AlaAla: 4.752 ± 0.831
1.296AlaCys: 1.296 ± 0.679
6.911AlaAsp: 6.911 ± 2.113
5.184AlaGlu: 5.184 ± 0.906
2.592AlaPhe: 2.592 ± 1.064
4.32AlaGly: 4.32 ± 1.987
1.296AlaHis: 1.296 ± 0.789
1.296AlaIle: 1.296 ± 0.378
4.32AlaLys: 4.32 ± 1.012
2.16AlaLeu: 2.16 ± 1.295
0.864AlaMet: 0.864 ± 0.697
1.296AlaAsn: 1.296 ± 0.699
4.32AlaPro: 4.32 ± 1.414
2.16AlaGln: 2.16 ± 0.64
3.024AlaArg: 3.024 ± 1.249
3.024AlaSer: 3.024 ± 1.032
4.32AlaThr: 4.32 ± 1.161
2.592AlaVal: 2.592 ± 0.744
1.296AlaTrp: 1.296 ± 0.616
2.16AlaTyr: 2.16 ± 0.643
0.0AlaXaa: 0.0 ± 0.0
Cys
1.296CysAla: 1.296 ± 1.039
1.728CysCys: 1.728 ± 1.795
1.296CysAsp: 1.296 ± 0.958
0.864CysGlu: 0.864 ± 1.233
2.16CysPhe: 2.16 ± 1.099
1.296CysGly: 1.296 ± 0.827
0.0CysHis: 0.0 ± 0.0
0.864CysIle: 0.864 ± 0.806
2.16CysLys: 2.16 ± 1.012
3.024CysLeu: 3.024 ± 1.869
0.864CysMet: 0.864 ± 1.103
0.0CysAsn: 0.0 ± 0.0
1.728CysPro: 1.728 ± 0.67
2.16CysGln: 2.16 ± 0.975
1.296CysArg: 1.296 ± 0.931
0.432CysSer: 0.432 ± 0.362
3.456CysThr: 3.456 ± 1.369
0.864CysVal: 0.864 ± 0.806
1.296CysTrp: 1.296 ± 0.666
0.864CysTyr: 0.864 ± 0.638
0.0CysXaa: 0.0 ± 0.0
Asp
3.456AspAla: 3.456 ± 0.69
2.16AspCys: 2.16 ± 0.404
2.592AspAsp: 2.592 ± 1.064
2.592AspGlu: 2.592 ± 1.358
1.728AspPhe: 1.728 ± 0.987
3.888AspGly: 3.888 ± 1.033
0.0AspHis: 0.0 ± 0.0
3.456AspIle: 3.456 ± 1.132
3.456AspLys: 3.456 ± 1.386
5.184AspLeu: 5.184 ± 1.963
2.16AspMet: 2.16 ± 0.643
2.16AspAsn: 2.16 ± 0.643
4.32AspPro: 4.32 ± 1.169
0.864AspGln: 0.864 ± 0.443
3.456AspArg: 3.456 ± 0.907
5.184AspSer: 5.184 ± 0.975
2.16AspThr: 2.16 ± 0.699
6.911AspVal: 6.911 ± 2.891
1.296AspTrp: 1.296 ± 0.666
1.728AspTyr: 1.728 ± 0.654
0.0AspXaa: 0.0 ± 0.0
Glu
6.048GluAla: 6.048 ± 1.465
0.432GluCys: 0.432 ± 0.319
6.048GluAsp: 6.048 ± 1.104
8.207GluGlu: 8.207 ± 1.712
2.592GluPhe: 2.592 ± 1.16
4.32GluGly: 4.32 ± 1.514
2.16GluHis: 2.16 ± 0.533
3.024GluIle: 3.024 ± 1.092
3.024GluLys: 3.024 ± 1.376
8.207GluLeu: 8.207 ± 1.36
1.296GluMet: 1.296 ± 0.328
2.592GluAsn: 2.592 ± 0.932
4.32GluPro: 4.32 ± 1.189
2.592GluGln: 2.592 ± 0.923
1.728GluArg: 1.728 ± 1.045
2.16GluSer: 2.16 ± 0.812
4.752GluThr: 4.752 ± 1.799
4.32GluVal: 4.32 ± 1.41
0.432GluTrp: 0.432 ± 0.373
1.728GluTyr: 1.728 ± 0.817
0.0GluXaa: 0.0 ± 0.0
Phe
3.024PheAla: 3.024 ± 0.461
0.864PheCys: 0.864 ± 1.233
2.16PheAsp: 2.16 ± 0.514
4.32PheGlu: 4.32 ± 2.595
2.16PhePhe: 2.16 ± 0.972
2.592PheGly: 2.592 ± 1.125
0.0PheHis: 0.0 ± 0.0
1.728PheIle: 1.728 ± 0.496
2.592PheLys: 2.592 ± 1.222
6.048PheLeu: 6.048 ± 1.889
0.864PheMet: 0.864 ± 0.686
1.296PheAsn: 1.296 ± 0.77
0.864PhePro: 0.864 ± 0.408
0.432PheGln: 0.432 ± 0.486
1.296PheArg: 1.296 ± 0.597
3.024PheSer: 3.024 ± 0.859
3.888PheThr: 3.888 ± 1.123
3.456PheVal: 3.456 ± 2.128
1.296PheTrp: 1.296 ± 0.378
2.592PheTyr: 2.592 ± 1.258
0.0PheXaa: 0.0 ± 0.0
Gly
3.024GlyAla: 3.024 ± 0.861
2.16GlyCys: 2.16 ± 0.906
3.456GlyAsp: 3.456 ± 0.894
3.888GlyGlu: 3.888 ± 1.263
1.296GlyPhe: 1.296 ± 0.328
9.503GlyGly: 9.503 ± 3.839
1.728GlyHis: 1.728 ± 0.886
1.728GlyIle: 1.728 ± 0.626
3.456GlyLys: 3.456 ± 0.921
4.32GlyLeu: 4.32 ± 1.287
0.864GlyMet: 0.864 ± 0.435
3.024GlyAsn: 3.024 ± 1.049
5.616GlyPro: 5.616 ± 1.256
0.864GlyGln: 0.864 ± 0.443
8.207GlyArg: 8.207 ± 2.82
5.616GlySer: 5.616 ± 1.4
6.911GlyThr: 6.911 ± 1.694
5.616GlyVal: 5.616 ± 1.207
0.0GlyTrp: 0.0 ± 0.0
1.728GlyTyr: 1.728 ± 0.67
0.0GlyXaa: 0.0 ± 0.0
His
0.432HisAla: 0.432 ± 0.319
1.296HisCys: 1.296 ± 0.77
0.432HisAsp: 0.432 ± 0.486
0.432HisGlu: 0.432 ± 0.319
0.432HisPhe: 0.432 ± 0.319
0.864HisGly: 0.864 ± 0.697
0.432HisHis: 0.432 ± 0.319
0.864HisIle: 0.864 ± 0.408
1.296HisLys: 1.296 ± 1.087
2.592HisLeu: 2.592 ± 1.122
0.864HisMet: 0.864 ± 0.408
0.864HisAsn: 0.864 ± 0.408
2.16HisPro: 2.16 ± 1.255
0.864HisGln: 0.864 ± 0.638
1.296HisArg: 1.296 ± 0.411
1.296HisSer: 1.296 ± 0.679
1.296HisThr: 1.296 ± 0.411
2.16HisVal: 2.16 ± 0.812
1.296HisTrp: 1.296 ± 0.597
0.432HisTyr: 0.432 ± 0.362
0.0HisXaa: 0.0 ± 0.0
Ile
2.16IleAla: 2.16 ± 0.64
0.864IleCys: 0.864 ± 0.798
3.888IleAsp: 3.888 ± 1.144
4.752IleGlu: 4.752 ± 1.4
2.16IlePhe: 2.16 ± 0.701
4.32IleGly: 4.32 ± 1.432
0.432IleHis: 0.432 ± 0.617
0.864IleIle: 0.864 ± 0.435
1.296IleLys: 1.296 ± 0.754
3.024IleLeu: 3.024 ± 0.624
0.864IleMet: 0.864 ± 0.441
0.864IleAsn: 0.864 ± 0.416
1.296IlePro: 1.296 ± 1.119
1.296IleGln: 1.296 ± 0.597
0.432IleArg: 0.432 ± 0.319
5.184IleSer: 5.184 ± 1.386
0.864IleThr: 0.864 ± 0.697
1.728IleVal: 1.728 ± 0.9
0.0IleTrp: 0.0 ± 0.0
1.728IleTyr: 1.728 ± 0.542
0.0IleXaa: 0.0 ± 0.0
Lys
3.888LysAla: 3.888 ± 1.2
3.024LysCys: 3.024 ± 0.866
3.888LysAsp: 3.888 ± 1.088
3.024LysGlu: 3.024 ± 0.866
2.592LysPhe: 2.592 ± 1.046
3.456LysGly: 3.456 ± 1.175
1.296LysHis: 1.296 ± 0.597
2.16LysIle: 2.16 ± 1.014
4.32LysLys: 4.32 ± 2.677
1.728LysLeu: 1.728 ± 0.542
1.296LysMet: 1.296 ± 1.21
3.024LysAsn: 3.024 ± 0.887
1.728LysPro: 1.728 ± 0.542
1.296LysGln: 1.296 ± 0.561
6.048LysArg: 6.048 ± 1.093
3.024LysSer: 3.024 ± 1.032
2.592LysThr: 2.592 ± 1.358
2.16LysVal: 2.16 ± 0.805
1.728LysTrp: 1.728 ± 1.134
3.456LysTyr: 3.456 ± 0.641
0.0LysXaa: 0.0 ± 0.0
Leu
6.911LeuAla: 6.911 ± 1.113
2.16LeuCys: 2.16 ± 1.463
4.752LeuAsp: 4.752 ± 0.9
8.207LeuGlu: 8.207 ± 1.503
4.32LeuPhe: 4.32 ± 0.836
7.343LeuGly: 7.343 ± 2.022
2.16LeuHis: 2.16 ± 1.01
3.024LeuIle: 3.024 ± 1.11
5.184LeuLys: 5.184 ± 1.416
9.935LeuLeu: 9.935 ± 3.968
0.432LeuMet: 0.432 ± 0.425
3.456LeuAsn: 3.456 ± 1.579
4.32LeuPro: 4.32 ± 0.665
3.024LeuGln: 3.024 ± 0.96
6.479LeuArg: 6.479 ± 2.266
4.752LeuSer: 4.752 ± 1.105
6.048LeuThr: 6.048 ± 2.38
2.592LeuVal: 2.592 ± 0.762
0.432LeuTrp: 0.432 ± 0.425
4.32LeuTyr: 4.32 ± 1.096
0.0LeuXaa: 0.0 ± 0.0
Met
1.296MetAla: 1.296 ± 0.766
1.296MetCys: 1.296 ± 0.931
1.728MetAsp: 1.728 ± 1.175
0.864MetGlu: 0.864 ± 0.697
2.16MetPhe: 2.16 ± 2.126
0.432MetGly: 0.432 ± 0.425
1.296MetHis: 1.296 ± 0.575
0.432MetIle: 0.432 ± 0.319
0.864MetLys: 0.864 ± 0.441
2.16MetLeu: 2.16 ± 1.041
0.864MetMet: 0.864 ± 0.501
0.864MetAsn: 0.864 ± 0.806
0.864MetPro: 0.864 ± 0.408
0.864MetGln: 0.864 ± 0.416
1.296MetArg: 1.296 ± 0.597
3.456MetSer: 3.456 ± 1.56
0.864MetThr: 0.864 ± 0.443
1.296MetVal: 1.296 ± 0.958
0.432MetTrp: 0.432 ± 0.425
0.432MetTyr: 0.432 ± 0.373
0.0MetXaa: 0.0 ± 0.0
Asn
3.888AsnAla: 3.888 ± 0.759
1.296AsnCys: 1.296 ± 0.853
0.864AsnAsp: 0.864 ± 0.618
1.728AsnGlu: 1.728 ± 0.987
1.728AsnPhe: 1.728 ± 0.622
3.024AsnGly: 3.024 ± 1.484
1.728AsnHis: 1.728 ± 0.853
0.864AsnIle: 0.864 ± 0.435
3.888AsnLys: 3.888 ± 1.311
3.024AsnLeu: 3.024 ± 0.986
1.296AsnMet: 1.296 ± 0.597
3.456AsnAsn: 3.456 ± 1.112
5.184AsnPro: 5.184 ± 1.736
1.728AsnGln: 1.728 ± 0.496
1.296AsnArg: 1.296 ± 0.759
5.184AsnSer: 5.184 ± 2.008
1.728AsnThr: 1.728 ± 0.739
0.864AsnVal: 0.864 ± 0.598
0.432AsnTrp: 0.432 ± 0.373
0.432AsnTyr: 0.432 ± 0.319
0.0AsnXaa: 0.0 ± 0.0
Pro
2.592ProAla: 2.592 ± 0.997
1.296ProCys: 1.296 ± 0.577
4.32ProAsp: 4.32 ± 0.847
3.888ProGlu: 3.888 ± 0.646
2.16ProPhe: 2.16 ± 1.195
3.888ProGly: 3.888 ± 1.55
0.864ProHis: 0.864 ± 0.408
2.592ProIle: 2.592 ± 0.901
1.728ProLys: 1.728 ± 0.817
5.616ProLeu: 5.616 ± 1.0
0.432ProMet: 0.432 ± 0.425
3.888ProAsn: 3.888 ± 1.582
4.32ProPro: 4.32 ± 0.673
2.16ProGln: 2.16 ± 0.974
3.456ProArg: 3.456 ± 0.963
5.616ProSer: 5.616 ± 1.531
4.32ProThr: 4.32 ± 1.595
5.184ProVal: 5.184 ± 2.17
1.296ProTrp: 1.296 ± 0.853
0.432ProTyr: 0.432 ± 0.425
0.0ProXaa: 0.0 ± 0.0
Gln
0.864GlnAla: 0.864 ± 0.408
1.296GlnCys: 1.296 ± 0.561
0.864GlnAsp: 0.864 ± 0.441
3.024GlnGlu: 3.024 ± 0.982
0.864GlnPhe: 0.864 ± 0.638
1.728GlnGly: 1.728 ± 0.572
0.864GlnHis: 0.864 ± 0.638
1.296GlnIle: 1.296 ± 0.512
0.432GlnLys: 0.432 ± 0.319
3.888GlnLeu: 3.888 ± 0.89
1.296GlnMet: 1.296 ± 0.378
0.432GlnAsn: 0.432 ± 0.319
1.728GlnPro: 1.728 ± 0.466
1.296GlnGln: 1.296 ± 0.679
0.864GlnArg: 0.864 ± 0.443
3.024GlnSer: 3.024 ± 1.029
3.456GlnThr: 3.456 ± 1.718
2.592GlnVal: 2.592 ± 0.558
0.432GlnTrp: 0.432 ± 0.319
0.864GlnTyr: 0.864 ± 0.85
0.0GlnXaa: 0.0 ± 0.0
Arg
3.024ArgAla: 3.024 ± 1.279
1.296ArgCys: 1.296 ± 0.741
2.592ArgAsp: 2.592 ± 0.854
0.864ArgGlu: 0.864 ± 0.501
2.592ArgPhe: 2.592 ± 0.823
4.752ArgGly: 4.752 ± 1.581
1.296ArgHis: 1.296 ± 0.77
2.16ArgIle: 2.16 ± 0.914
6.048ArgLys: 6.048 ± 1.654
8.207ArgLeu: 8.207 ± 1.281
2.16ArgMet: 2.16 ± 0.624
2.16ArgAsn: 2.16 ± 0.762
4.32ArgPro: 4.32 ± 1.625
1.296ArgGln: 1.296 ± 0.328
5.616ArgArg: 5.616 ± 2.233
3.888ArgSer: 3.888 ± 0.892
3.456ArgThr: 3.456 ± 0.59
3.024ArgVal: 3.024 ± 0.607
0.0ArgTrp: 0.0 ± 0.0
0.864ArgTyr: 0.864 ± 0.618
0.0ArgXaa: 0.0 ± 0.0
Ser
3.456SerAla: 3.456 ± 0.793
1.296SerCys: 1.296 ± 0.77
3.456SerAsp: 3.456 ± 1.005
6.911SerGlu: 6.911 ± 2.2
5.616SerPhe: 5.616 ± 0.783
4.32SerGly: 4.32 ± 0.958
3.024SerHis: 3.024 ± 0.934
3.024SerIle: 3.024 ± 0.887
3.024SerLys: 3.024 ± 1.372
5.616SerLeu: 5.616 ± 1.343
1.728SerMet: 1.728 ± 0.97
4.32SerAsn: 4.32 ± 1.751
3.456SerPro: 3.456 ± 1.304
2.592SerGln: 2.592 ± 0.46
4.32SerArg: 4.32 ± 1.374
5.184SerSer: 5.184 ± 2.145
5.184SerThr: 5.184 ± 0.868
3.024SerVal: 3.024 ± 0.9
1.296SerTrp: 1.296 ± 0.378
1.728SerTyr: 1.728 ± 0.87
0.0SerXaa: 0.0 ± 0.0
Thr
4.752ThrAla: 4.752 ± 0.668
1.728ThrCys: 1.728 ± 1.235
3.024ThrAsp: 3.024 ± 1.048
4.32ThrGlu: 4.32 ± 0.948
3.024ThrPhe: 3.024 ± 1.293
3.888ThrGly: 3.888 ± 0.646
0.432ThrHis: 0.432 ± 0.425
2.16ThrIle: 2.16 ± 1.025
3.456ThrLys: 3.456 ± 1.403
4.32ThrLeu: 4.32 ± 1.583
2.592ThrMet: 2.592 ± 0.797
3.888ThrAsn: 3.888 ± 1.266
4.32ThrPro: 4.32 ± 1.842
2.16ThrGln: 2.16 ± 0.404
3.456ThrArg: 3.456 ± 0.925
5.184ThrSer: 5.184 ± 1.264
4.752ThrThr: 4.752 ± 1.699
5.616ThrVal: 5.616 ± 1.439
0.0ThrTrp: 0.0 ± 0.0
0.432ThrTyr: 0.432 ± 0.425
0.0ThrXaa: 0.0 ± 0.0
Val
2.592ValAla: 2.592 ± 1.49
0.864ValCys: 0.864 ± 0.972
3.888ValAsp: 3.888 ± 0.357
5.184ValGlu: 5.184 ± 1.326
3.024ValPhe: 3.024 ± 0.844
5.184ValGly: 5.184 ± 2.084
1.296ValHis: 1.296 ± 0.806
5.184ValIle: 5.184 ± 1.343
2.592ValLys: 2.592 ± 1.503
6.048ValLeu: 6.048 ± 1.715
0.432ValMet: 0.432 ± 0.362
1.296ValAsn: 1.296 ± 0.328
3.024ValPro: 3.024 ± 1.05
2.592ValGln: 2.592 ± 0.852
3.888ValArg: 3.888 ± 1.261
6.048ValSer: 6.048 ± 1.732
1.728ValThr: 1.728 ± 1.256
5.616ValVal: 5.616 ± 2.024
0.432ValTrp: 0.432 ± 0.425
1.728ValTyr: 1.728 ± 0.886
0.0ValXaa: 0.0 ± 0.0
Trp
0.432TrpAla: 0.432 ± 0.319
0.864TrpCys: 0.864 ± 0.855
0.432TrpAsp: 0.432 ± 0.362
0.432TrpGlu: 0.432 ± 0.425
0.0TrpPhe: 0.0 ± 0.0
2.16TrpGly: 2.16 ± 0.812
0.432TrpHis: 0.432 ± 0.362
0.0TrpIle: 0.0 ± 0.0
0.864TrpLys: 0.864 ± 0.638
1.728TrpLeu: 1.728 ± 0.866
0.0TrpMet: 0.0 ± 0.0
2.16TrpAsn: 2.16 ± 1.388
0.0TrpPro: 0.0 ± 0.0
0.432TrpGln: 0.432 ± 0.362
0.864TrpArg: 0.864 ± 0.65
0.0TrpSer: 0.0 ± 0.0
1.296TrpThr: 1.296 ± 0.791
1.296TrpVal: 1.296 ± 0.601
0.0TrpTrp: 0.0 ± 0.0
0.432TrpTyr: 0.432 ± 0.319
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.296TyrAla: 1.296 ± 0.328
0.864TyrCys: 0.864 ± 0.618
2.16TyrAsp: 2.16 ± 1.012
1.296TyrGlu: 1.296 ± 0.689
1.296TyrPhe: 1.296 ± 0.77
1.728TyrGly: 1.728 ± 0.618
0.864TyrHis: 0.864 ± 0.416
1.296TyrIle: 1.296 ± 0.577
1.728TyrLys: 1.728 ± 1.277
3.024TyrLeu: 3.024 ± 0.427
2.16TyrMet: 2.16 ± 0.774
2.592TyrAsn: 2.592 ± 0.53
2.16TyrPro: 2.16 ± 1.6
0.432TyrGln: 0.432 ± 0.319
1.296TyrArg: 1.296 ± 0.667
1.296TyrSer: 1.296 ± 0.328
0.432TyrThr: 0.432 ± 0.373
1.728TyrVal: 1.728 ± 0.254
0.432TyrTrp: 0.432 ± 0.362
3.024TyrTyr: 3.024 ± 1.056
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2316 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski