Proteome-pI 2.0 - Proteome Isoelectric Point Database

Helianthus annuus alphaendornavirus

Taxonomy: Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes; Martellivirales; Endornaviridae; Alphaendornavirus

Average proteome isoelectric point is 6.75

Get precalculated fractions of proteins

Acidic

pI < 6.8

6.8-7.4

pI > 7.4

Basic

All

Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions

Protein with the lowest isoelectric point:

>tr|A0A2U8JGM0|A0A2U8JGM0_9VIRU Polyprotein OS=Helianthus annuus alphaendornavirus OX=2184469 PE=4 SV=1

MM1 pKa = 8.22DD2 pKa = 4.74ILKK5 pKa = 10.33KK6 pKa = 10.08EE7 pKa = 4.38PKK9 pKa = 9.76PKK11 pKa = 10.63GEE13 pKa = 4.02PSSIQHH19 pKa = 6.74AGDD22 pKa = 4.17GPPSVLNVGEE32 pKa = 3.88ILANINKK39 pKa = 9.39LVSARR44 pKa = 11.84DD45 pKa = 3.42RR46 pKa = 11.84RR47 pKa = 11.84RR48 pKa = 11.84QTLRR52 pKa = 11.84TKK54 pKa = 8.24TRR56 pKa = 11.84RR57 pKa = 11.84LTEE60 pKa = 3.94NNEE63 pKa = 3.93FNVKK67 pKa = 9.52VDD69 pKa = 3.02PHH71 pKa = 6.07FQPKK75 pKa = 9.17FVKK78 pKa = 10.47CVAGSNKK85 pKa = 9.51QSMKK89 pKa = 10.35KK90 pKa = 10.04SPHH93 pKa = 5.33KK94 pKa = 8.44WQHH97 pKa = 4.34NVMVFNTINLGKK109 pKa = 9.81RR110 pKa = 11.84DD111 pKa = 3.61PHH113 pKa = 6.56EE114 pKa = 4.22IANKK118 pKa = 9.48LLAYY122 pKa = 7.97GAPAKK127 pKa = 10.98VKK129 pKa = 10.25DD130 pKa = 4.32CQCASCVSVDD140 pKa = 3.53NQRR143 pKa = 11.84SKK145 pKa = 11.41VAINTQATLGMWSITKK161 pKa = 9.93DD162 pKa = 3.18PCALEE167 pKa = 4.92GIDD170 pKa = 3.91IIKK173 pKa = 10.06YY174 pKa = 8.56RR175 pKa = 11.84PKK177 pKa = 10.53AIHH180 pKa = 6.05QLLSTEE186 pKa = 3.91QEE188 pKa = 4.01FRR190 pKa = 11.84KK191 pKa = 8.15TLWDD195 pKa = 4.09FKK197 pKa = 11.16LEE199 pKa = 4.08KK200 pKa = 10.18TLDD203 pKa = 3.61EE204 pKa = 4.45VVTGKK209 pKa = 10.23DD210 pKa = 2.91QFKK213 pKa = 10.53AHH215 pKa = 6.29MRR217 pKa = 11.84RR218 pKa = 11.84QFTKK222 pKa = 10.13YY223 pKa = 9.36LKK225 pKa = 10.51KK226 pKa = 10.27FSGYY230 pKa = 9.95QGLITEE236 pKa = 5.44ALTQTTRR243 pKa = 11.84CVPWAQVYY251 pKa = 9.75DD252 pKa = 3.59IRR254 pKa = 11.84TGEE257 pKa = 3.87PLANQFSHH265 pKa = 7.15RR266 pKa = 11.84KK267 pKa = 5.46PTPEE271 pKa = 4.58EE272 pKa = 3.69RR273 pKa = 11.84TQMITCPHH281 pKa = 6.55CKK283 pKa = 8.85CTNSLIVPRR292 pKa = 11.84DD293 pKa = 3.82LKK295 pKa = 10.97PKK297 pKa = 10.54LVDD300 pKa = 3.96LTDD303 pKa = 3.82HH304 pKa = 7.0RR305 pKa = 11.84CGACGRR311 pKa = 11.84PFQEE315 pKa = 4.9QMHH318 pKa = 6.83DD319 pKa = 2.98PWAEE323 pKa = 3.6IFDD326 pKa = 4.15IFDD329 pKa = 3.25EE330 pKa = 4.83SINPNVGAQTEE341 pKa = 4.38MMKK344 pKa = 11.01LMGRR348 pKa = 11.84LDD350 pKa = 3.38MSEE353 pKa = 3.66IDD355 pKa = 3.49EE356 pKa = 5.65AYY358 pKa = 9.57TLMDD362 pKa = 3.39IAEE365 pKa = 4.24KK366 pKa = 10.63HH367 pKa = 5.34DD368 pKa = 3.46TRR370 pKa = 11.84LVKK373 pKa = 10.53SALSRR378 pKa = 11.84LQLDD382 pKa = 4.18LVDD385 pKa = 4.26VPLNMEE391 pKa = 4.03KK392 pKa = 10.66SKK394 pKa = 11.3LGVLDD399 pKa = 3.48QLFGGFEE406 pKa = 4.08FVPKK410 pKa = 10.05PGLVTDD416 pKa = 4.66TPLEE420 pKa = 4.11DD421 pKa = 3.33TFRR424 pKa = 11.84NAVMTMVKK432 pKa = 8.61KK433 pKa = 7.48TTMSEE438 pKa = 3.72GFYY441 pKa = 10.61WPDD444 pKa = 3.26AYY446 pKa = 10.78QKK448 pKa = 10.48PNSSRR453 pKa = 11.84LNVVNPYY460 pKa = 9.08QCCGSLEE467 pKa = 4.01CDD469 pKa = 2.63HH470 pKa = 7.04WIKK473 pKa = 11.13KK474 pKa = 7.42NTFITLEE481 pKa = 4.09SLSVGLNGILKK492 pKa = 9.4MIEE495 pKa = 4.02RR496 pKa = 11.84SGKK499 pKa = 8.02EE500 pKa = 3.46AWVCLPTEE508 pKa = 4.94GYY510 pKa = 9.82NPKK513 pKa = 10.19ADD515 pKa = 3.19SGQFEE520 pKa = 4.33GGEE523 pKa = 4.24THH525 pKa = 5.74YY526 pKa = 10.74HH527 pKa = 6.25LSGHH531 pKa = 5.05VMKK534 pKa = 9.81LTRR537 pKa = 11.84PGHH540 pKa = 6.67DD541 pKa = 3.15YY542 pKa = 11.57PMIVDD547 pKa = 3.36KK548 pKa = 10.93TDD550 pKa = 3.32YY551 pKa = 11.3EE552 pKa = 4.28NLTEE556 pKa = 4.55GDD558 pKa = 3.63IFHH561 pKa = 7.34GSTGTYY567 pKa = 7.85MATTILTGCGHH578 pKa = 7.29KK579 pKa = 10.56VRR581 pKa = 11.84IIKK584 pKa = 10.4KK585 pKa = 7.82VDD587 pKa = 3.66LNIGEE592 pKa = 5.36IIPKK596 pKa = 10.17LKK598 pKa = 8.57PTKK601 pKa = 10.26ARR603 pKa = 11.84PQTFKK608 pKa = 10.82IPTVLPGSLGSITGILTSSVKK629 pKa = 10.2EE630 pKa = 4.08VTVEE634 pKa = 3.77PTLLKK639 pKa = 10.82SLMIKK644 pKa = 10.5NLDD647 pKa = 3.29ASMTFAEE654 pKa = 4.32LLEE657 pKa = 4.41FGMAFSFTRR666 pKa = 11.84YY667 pKa = 9.28HH668 pKa = 6.7RR669 pKa = 11.84GEE671 pKa = 4.15KK672 pKa = 9.89VISYY676 pKa = 10.72QDD678 pKa = 3.39LTSTQVIDD686 pKa = 3.51HH687 pKa = 6.29CVIALILTRR696 pKa = 11.84RR697 pKa = 11.84AMAARR702 pKa = 11.84TMIVSATQKK711 pKa = 9.79NSVMEE716 pKa = 4.43VIQSAGLSVGMTTAVTLLEE735 pKa = 5.33GITNTTIKK743 pKa = 10.73SSLKK747 pKa = 8.86TLMSRR752 pKa = 11.84VDD754 pKa = 4.13AISVNSLRR762 pKa = 11.84VIGEE766 pKa = 4.0HH767 pKa = 6.25PVWDD771 pKa = 5.55DD772 pKa = 3.07IQRR775 pKa = 11.84WTTKK779 pKa = 8.88VTLSSYY785 pKa = 10.58RR786 pKa = 11.84IIDD789 pKa = 3.74YY790 pKa = 10.56RR791 pKa = 11.84PLRR794 pKa = 11.84ATIRR798 pKa = 11.84KK799 pKa = 8.31EE800 pKa = 4.01VTCPHH805 pKa = 5.85VLSVIEE811 pKa = 5.58QGDD814 pKa = 4.06QQCLCCGRR822 pKa = 11.84LARR825 pKa = 11.84SDD827 pKa = 3.54MCKK830 pKa = 10.51DD831 pKa = 4.19CSPCANKK838 pKa = 9.82EE839 pKa = 4.06HH840 pKa = 6.83ACSHH844 pKa = 5.96TCVHH848 pKa = 6.1DD849 pKa = 3.78HH850 pKa = 6.94KK851 pKa = 11.42GEE853 pKa = 4.13KK854 pKa = 9.72KK855 pKa = 10.35CLCCQLPSEE864 pKa = 4.68NKK866 pKa = 9.38VCTCCKK872 pKa = 8.68VHH874 pKa = 6.59YY875 pKa = 10.12SVADD879 pKa = 3.49MVGQPTKK886 pKa = 10.82KK887 pKa = 8.62PTKK890 pKa = 10.18KK891 pKa = 10.01PEE893 pKa = 3.82QPKK896 pKa = 10.02RR897 pKa = 11.84DD898 pKa = 3.63SSSKK902 pKa = 6.71QTKK905 pKa = 9.52PEE907 pKa = 3.93QKK909 pKa = 9.51PGPKK913 pKa = 8.8TRR915 pKa = 11.84EE916 pKa = 4.01EE917 pKa = 3.98EE918 pKa = 3.7QGQYY922 pKa = 10.68NDD924 pKa = 3.34EE925 pKa = 4.52DD926 pKa = 3.97EE927 pKa = 4.76VVIEE931 pKa = 3.83AAEE934 pKa = 4.2RR935 pKa = 11.84EE936 pKa = 4.2DD937 pKa = 5.5ALIQQTSLDD946 pKa = 3.95FVTALLSPEE955 pKa = 3.93AWPTEE960 pKa = 3.97ATKK963 pKa = 10.84NPPCGDD969 pKa = 2.99IPMGSRR975 pKa = 11.84ILYY978 pKa = 9.96VPMGLTIGEE987 pKa = 4.39SKK989 pKa = 10.3SVKK992 pKa = 8.64VTSHH996 pKa = 5.97KK997 pKa = 10.68VIPNKK1002 pKa = 10.51EE1003 pKa = 4.28GTCGLDD1009 pKa = 3.27ALRR1012 pKa = 11.84LGMGEE1017 pKa = 4.06QVTISVMEE1025 pKa = 4.14TVTKK1029 pKa = 9.28KK1030 pKa = 8.7TRR1032 pKa = 11.84GWDD1035 pKa = 3.27VDD1037 pKa = 4.19DD1038 pKa = 4.35LLKK1041 pKa = 10.91VGKK1044 pKa = 10.1ALGKK1048 pKa = 10.13NVLVLTGTEE1057 pKa = 3.94VHH1059 pKa = 6.04VMKK1062 pKa = 10.93SNSEE1066 pKa = 4.09DD1067 pKa = 3.53DD1068 pKa = 3.72YY1069 pKa = 11.27HH1070 pKa = 7.13TIIHH1074 pKa = 5.48STALNKK1080 pKa = 10.07EE1081 pKa = 4.15GQHH1084 pKa = 6.11WYY1086 pKa = 9.49PGTVQQVGVIRR1097 pKa = 11.84KK1098 pKa = 8.02EE1099 pKa = 3.89VVYY1102 pKa = 10.93NPTITMQTMHH1112 pKa = 7.55KK1113 pKa = 9.95IAQQVTRR1120 pKa = 11.84KK1121 pKa = 9.58KK1122 pKa = 9.88VNHH1125 pKa = 6.32YY1126 pKa = 10.47DD1127 pKa = 3.25VALMEE1132 pKa = 4.46RR1133 pKa = 11.84KK1134 pKa = 9.32EE1135 pKa = 4.72LIDD1138 pKa = 3.57LHH1140 pKa = 6.52VAAATVAEE1148 pKa = 4.63TIKK1151 pKa = 10.39IHH1153 pKa = 5.45TVVDD1157 pKa = 3.5KK1158 pKa = 11.34NFRR1161 pKa = 11.84LEE1163 pKa = 4.18TNQDD1167 pKa = 2.69EE1168 pKa = 4.68QYY1170 pKa = 11.33LVNNKK1175 pKa = 8.05EE1176 pKa = 3.83RR1177 pKa = 11.84EE1178 pKa = 4.02HH1179 pKa = 6.61NIRR1182 pKa = 11.84EE1183 pKa = 4.19GKK1185 pKa = 9.48ICVIVPTYY1193 pKa = 9.4LLSVIRR1199 pKa = 11.84HH1200 pKa = 5.43LTRR1203 pKa = 11.84LSPDD1207 pKa = 3.69SISNDD1212 pKa = 3.23DD1213 pKa = 3.5VNTIFDD1219 pKa = 4.52KK1220 pKa = 10.94DD1221 pKa = 3.75DD1222 pKa = 4.2QIPEE1226 pKa = 4.33TLNAWIKK1233 pKa = 11.16SEE1235 pKa = 4.25VADD1238 pKa = 3.83CVKK1241 pKa = 10.24TILYY1245 pKa = 8.76ALCYY1249 pKa = 10.25DD1250 pKa = 4.88VIPKK1254 pKa = 8.41STNPLRR1260 pKa = 11.84ITYY1263 pKa = 9.09EE1264 pKa = 4.2KK1265 pKa = 10.73FDD1267 pKa = 4.39MIQDD1271 pKa = 3.96GTRR1274 pKa = 11.84TVLDD1278 pKa = 3.37VSRR1281 pKa = 11.84TKK1283 pKa = 10.81LKK1285 pKa = 10.83SLDD1288 pKa = 3.74VIYY1291 pKa = 10.28LHH1293 pKa = 6.71QDD1295 pKa = 2.95GKK1297 pKa = 10.7IVPTMINPKK1306 pKa = 8.42MGKK1309 pKa = 9.16IAITTDD1315 pKa = 2.39KK1316 pKa = 10.83SYY1318 pKa = 11.08RR1319 pKa = 11.84NKK1321 pKa = 10.61GMTIGIPQISIGSAIRR1337 pKa = 11.84NLASLLTMNTQSTYY1351 pKa = 11.73AMSKK1355 pKa = 10.78LEE1357 pKa = 4.19DD1358 pKa = 3.73SVMVLAPPGAGKK1370 pKa = 7.2TTEE1373 pKa = 3.72IMKK1376 pKa = 10.62LLTEE1380 pKa = 4.23SSLVVASTGGALNSLRR1396 pKa = 11.84QKK1398 pKa = 10.71KK1399 pKa = 9.43PPCQVLSVEE1408 pKa = 4.13AGKK1411 pKa = 10.47NYY1413 pKa = 10.2DD1414 pKa = 3.66LQVDD1418 pKa = 3.71HH1419 pKa = 6.97LVIDD1423 pKa = 3.77EE1424 pKa = 4.31CTTVGFLDD1432 pKa = 3.73YY1433 pKa = 10.73KK1434 pKa = 11.17AIVDD1438 pKa = 3.61KK1439 pKa = 11.25VKK1441 pKa = 10.15PKK1443 pKa = 10.59KK1444 pKa = 10.62VFAFGDD1450 pKa = 3.64TSQIGLKK1457 pKa = 10.36DD1458 pKa = 3.41MRR1460 pKa = 11.84ISAGTRR1466 pKa = 11.84AIQGLNTYY1474 pKa = 9.52HH1475 pKa = 7.78KK1476 pKa = 10.41SIKK1479 pKa = 9.82KK1480 pKa = 9.98LNHH1483 pKa = 5.95TYY1485 pKa = 10.69RR1486 pKa = 11.84IGQPLSNVLSEE1497 pKa = 4.5VYY1499 pKa = 10.7NDD1501 pKa = 4.16LEE1503 pKa = 4.51SKK1505 pKa = 10.87AEE1507 pKa = 3.95HH1508 pKa = 5.94KK1509 pKa = 9.79TDD1511 pKa = 5.16FEE1513 pKa = 5.35VIWSSHH1519 pKa = 5.62FDD1521 pKa = 3.49PEE1523 pKa = 4.47TVYY1526 pKa = 11.12EE1527 pKa = 4.39KK1528 pKa = 10.87ALKK1531 pKa = 10.24HH1532 pKa = 6.07NYY1534 pKa = 9.71DD1535 pKa = 4.05VILVHH1540 pKa = 6.05YY1541 pKa = 9.07RR1542 pKa = 11.84SHH1544 pKa = 7.23KK1545 pKa = 10.47AALLQQLNIIARR1557 pKa = 11.84GNTPLAQWARR1567 pKa = 11.84RR1568 pKa = 11.84VRR1570 pKa = 11.84VEE1572 pKa = 4.64TIHH1575 pKa = 6.92SYY1577 pKa = 10.34QGQEE1581 pKa = 3.48ADD1583 pKa = 3.07KK1584 pKa = 11.39VMVIQRR1590 pKa = 11.84SNQAGGSIEE1599 pKa = 5.54FDD1601 pKa = 3.14PQYY1604 pKa = 10.9NISAASRR1611 pKa = 11.84AKK1613 pKa = 10.44KK1614 pKa = 9.79HH1615 pKa = 5.05LTWYY1619 pKa = 10.34AVGVHH1624 pKa = 5.91SPNVDD1629 pKa = 2.85LGTILRR1635 pKa = 11.84PSKK1638 pKa = 10.94NIVGYY1643 pKa = 10.46GLFDD1647 pKa = 3.32MFSRR1651 pKa = 11.84FHH1653 pKa = 6.95TDD1655 pKa = 3.82TIQEE1659 pKa = 4.39SVKK1662 pKa = 10.38QPRR1665 pKa = 11.84LKK1667 pKa = 10.13KK1668 pKa = 9.87RR1669 pKa = 11.84KK1670 pKa = 9.36GIGRR1674 pKa = 11.84QFLKK1678 pKa = 10.27TINNYY1683 pKa = 9.86LDD1685 pKa = 3.46RR1686 pKa = 11.84KK1687 pKa = 9.28YY1688 pKa = 10.84KK1689 pKa = 9.54ATATLVEE1696 pKa = 4.18THH1698 pKa = 6.59DD1699 pKa = 4.73RR1700 pKa = 11.84EE1701 pKa = 4.19VLKK1704 pKa = 10.79IKK1706 pKa = 10.78VSVITMAEE1714 pKa = 4.01VTISADD1720 pKa = 3.43GTIKK1724 pKa = 10.7EE1725 pKa = 4.19GLNRR1729 pKa = 11.84VGDD1732 pKa = 4.2LSQLIDD1738 pKa = 5.12LIHH1741 pKa = 7.09SNLEE1745 pKa = 4.12DD1746 pKa = 4.37KK1747 pKa = 9.87PTMTCSCNTISKK1759 pKa = 9.68IPSHH1763 pKa = 5.8KK1764 pKa = 9.66TMNQLEE1770 pKa = 4.62FNTCLRR1776 pKa = 11.84LCNLNWVACEE1786 pKa = 3.57MAMVGEE1792 pKa = 4.32TLRR1795 pKa = 11.84LAVGDD1800 pKa = 3.82KK1801 pKa = 10.92LYY1803 pKa = 11.26DD1804 pKa = 3.51FVNPGEE1810 pKa = 4.2CHH1812 pKa = 5.59VCSKK1816 pKa = 7.63TTIVHH1821 pKa = 5.64QEE1823 pKa = 3.95TEE1825 pKa = 3.76IVRR1828 pKa = 11.84INRR1831 pKa = 11.84SHH1833 pKa = 7.0HH1834 pKa = 5.0FHH1836 pKa = 6.67TDD1838 pKa = 2.59VSIEE1842 pKa = 3.87YY1843 pKa = 10.08LIPEE1847 pKa = 4.15EE1848 pKa = 4.03NLLVEE1853 pKa = 5.62HH1854 pKa = 7.0FDD1856 pKa = 4.13LMNNLGLDD1864 pKa = 3.62EE1865 pKa = 3.93QLITHH1870 pKa = 6.52EE1871 pKa = 4.6RR1872 pKa = 11.84RR1873 pKa = 11.84PVDD1876 pKa = 3.61SPLLTRR1882 pKa = 11.84LANTEE1887 pKa = 4.06LTINTYY1893 pKa = 8.99VLQMRR1898 pKa = 11.84KK1899 pKa = 9.98SIEE1902 pKa = 4.07TTLKK1906 pKa = 9.03RR1907 pKa = 11.84TGNFIVDD1914 pKa = 3.53SLFGLKK1920 pKa = 10.16HH1921 pKa = 4.79EE1922 pKa = 5.29TIDD1925 pKa = 4.76SEE1927 pKa = 4.61TWCQSRR1933 pKa = 11.84GLTCLATIGNEE1944 pKa = 3.61MSRR1947 pKa = 11.84LVKK1950 pKa = 10.73VEE1952 pKa = 3.43VDD1954 pKa = 3.16NRR1956 pKa = 11.84IALMLPIEE1964 pKa = 5.21DD1965 pKa = 4.16SPIHH1969 pKa = 5.47YY1970 pKa = 10.41LEE1972 pKa = 4.74EE1973 pKa = 3.94EE1974 pKa = 4.4GKK1976 pKa = 10.42RR1977 pKa = 11.84DD1978 pKa = 4.02DD1979 pKa = 3.7NCKK1982 pKa = 9.72TMEE1985 pKa = 4.31EE1986 pKa = 4.62FIMEE1990 pKa = 4.54YY1991 pKa = 10.32INTLNTDD1998 pKa = 3.47GLLTKK2003 pKa = 9.85MISILGQMKK2012 pKa = 10.46VGGRR2016 pKa = 11.84DD2017 pKa = 3.33DD2018 pKa = 4.14LVNFEE2023 pKa = 4.54GLMVPYY2029 pKa = 9.07EE2030 pKa = 3.72RR2031 pKa = 11.84HH2032 pKa = 4.87MARR2035 pKa = 11.84KK2036 pKa = 9.51DD2037 pKa = 4.03RR2038 pKa = 11.84VWHH2041 pKa = 4.94TVVNKK2046 pKa = 9.89LGKK2049 pKa = 9.69MYY2051 pKa = 10.75VEE2053 pKa = 4.68SKK2055 pKa = 10.42RR2056 pKa = 11.84GEE2058 pKa = 3.94DD2059 pKa = 3.48SILYY2063 pKa = 10.24LSQTQIRR2070 pKa = 11.84EE2071 pKa = 3.7QGRR2074 pKa = 11.84LIKK2077 pKa = 10.35QQFPHH2082 pKa = 6.65LAINEE2087 pKa = 4.2HH2088 pKa = 6.89RR2089 pKa = 11.84YY2090 pKa = 9.65MMDD2093 pKa = 2.89SDD2095 pKa = 5.6DD2096 pKa = 4.09YY2097 pKa = 11.81GSTLEE2102 pKa = 3.79QLINHH2107 pKa = 6.0VLLNDD2112 pKa = 3.64SVGKK2116 pKa = 10.19VDD2118 pKa = 3.53YY2119 pKa = 9.65VTYY2122 pKa = 10.28RR2123 pKa = 11.84PHH2125 pKa = 8.5LVILNSRR2132 pKa = 11.84INCRR2136 pKa = 11.84LVEE2139 pKa = 4.32PNHH2142 pKa = 5.88NRR2144 pKa = 11.84LLTARR2149 pKa = 11.84SKK2151 pKa = 10.78INEE2154 pKa = 4.03TFMEE2158 pKa = 4.94GMCRR2162 pKa = 11.84NVEE2165 pKa = 3.99EE2166 pKa = 5.69AILTMASEE2174 pKa = 4.22NEE2176 pKa = 3.79KK2177 pKa = 11.16DD2178 pKa = 3.52EE2179 pKa = 4.49LVAITKK2185 pKa = 10.1QKK2187 pKa = 11.19LEE2189 pKa = 4.2LAQKK2193 pKa = 10.32CIRR2196 pKa = 11.84QKK2198 pKa = 10.31QGNWHH2203 pKa = 6.46PSKK2206 pKa = 9.84TFSKK2210 pKa = 10.07DD2211 pKa = 2.54TDD2213 pKa = 4.77LICLGEE2219 pKa = 4.7CGLSYY2224 pKa = 10.68EE2225 pKa = 4.42PSQLAQLVMEE2235 pKa = 4.27NSGRR2239 pKa = 11.84RR2240 pKa = 11.84IIIWGPNPALAKK2252 pKa = 10.17LDD2254 pKa = 3.61QLEE2257 pKa = 4.51VEE2259 pKa = 4.34GQEE2262 pKa = 4.14YY2263 pKa = 11.0LNVVDD2268 pKa = 5.15KK2269 pKa = 10.56RR2270 pKa = 11.84TGGHH2274 pKa = 5.92YY2275 pKa = 9.9IIHH2278 pKa = 5.96SGIWDD2283 pKa = 3.53SMKK2286 pKa = 10.7YY2287 pKa = 10.21GLPIAQEE2294 pKa = 4.19EE2295 pKa = 4.52KK2296 pKa = 10.37TSVLLASYY2304 pKa = 7.49MTIGGLIVYY2313 pKa = 8.36DD2314 pKa = 3.88VKK2316 pKa = 10.69IKK2318 pKa = 10.55RR2319 pKa = 11.84PQDD2322 pKa = 3.22IEE2324 pKa = 4.39LSWFAPLDD2332 pKa = 3.73SSKK2335 pKa = 8.17TTGLITIEE2343 pKa = 4.16VPHH2346 pKa = 6.56IHH2348 pKa = 6.95RR2349 pKa = 11.84DD2350 pKa = 3.5VVKK2353 pKa = 10.12LAKK2356 pKa = 10.0EE2357 pKa = 3.96GVPIISTRR2365 pKa = 11.84RR2366 pKa = 11.84IVADD2370 pKa = 3.61ARR2372 pKa = 11.84LLSNLAKK2379 pKa = 10.54RR2380 pKa = 11.84MLRR2383 pKa = 11.84PTTFDD2388 pKa = 2.99EE2389 pKa = 4.42LLNYY2393 pKa = 10.23ARR2395 pKa = 11.84VLAHH2399 pKa = 6.68GKK2401 pKa = 9.74HH2402 pKa = 5.6YY2403 pKa = 10.34SLKK2406 pKa = 10.23GFTSVYY2412 pKa = 10.56EE2413 pKa = 4.07EE2414 pKa = 4.62TPQEE2418 pKa = 3.96LLDD2421 pKa = 3.54ITMGVYY2427 pKa = 10.94LIYY2430 pKa = 10.83SRR2432 pKa = 11.84TIEE2435 pKa = 4.19SMEE2438 pKa = 3.74GMTEE2442 pKa = 4.39GIISRR2447 pKa = 11.84RR2448 pKa = 11.84DD2449 pKa = 3.09QDD2451 pKa = 4.01LDD2453 pKa = 3.44TFKK2456 pKa = 11.15AVLTEE2461 pKa = 4.22RR2462 pKa = 11.84VADD2465 pKa = 4.93FKK2467 pKa = 11.02TGLLGLVSKK2476 pKa = 9.2YY2477 pKa = 9.39TGLDD2481 pKa = 3.18LDD2483 pKa = 4.03LSDD2486 pKa = 3.92WLRR2489 pKa = 11.84ILSSGSRR2496 pKa = 11.84DD2497 pKa = 3.42HH2498 pKa = 7.2LSVIRR2503 pKa = 11.84QMITTLKK2510 pKa = 8.48HH2511 pKa = 4.13TRR2513 pKa = 11.84ARR2515 pKa = 11.84LLDD2518 pKa = 3.45DD2519 pKa = 3.46TRR2521 pKa = 11.84NIFPRR2526 pKa = 11.84PTVGSAPEE2534 pKa = 3.89SKK2536 pKa = 9.75IEE2538 pKa = 4.51KK2539 pKa = 9.58KK2540 pKa = 10.51DD2541 pKa = 3.44YY2542 pKa = 10.9SNNPFRR2548 pKa = 11.84FLEE2551 pKa = 4.0LAIDD2555 pKa = 3.91NVKK2558 pKa = 10.65ALAKK2562 pKa = 9.51LTFDD2566 pKa = 3.5NTHH2569 pKa = 6.19GSFKK2573 pKa = 10.3TATKK2577 pKa = 9.59PAIDD2581 pKa = 3.25KK2582 pKa = 9.04VVPQRR2587 pKa = 11.84RR2588 pKa = 11.84IADD2591 pKa = 3.46SHH2593 pKa = 6.07PTSDD2597 pKa = 3.94YY2598 pKa = 11.31LNMIEE2603 pKa = 4.36KK2604 pKa = 10.36SAMLTYY2610 pKa = 10.57QKK2612 pKa = 10.33FQQLPEE2618 pKa = 3.93FDD2620 pKa = 3.49YY2621 pKa = 11.93GEE2623 pKa = 4.3AYY2625 pKa = 9.52KK2626 pKa = 10.59KK2627 pKa = 10.73KK2628 pKa = 10.35LMEE2631 pKa = 4.22FQEE2634 pKa = 4.4VLEE2637 pKa = 4.35HH2638 pKa = 6.26AKK2640 pKa = 10.26KK2641 pKa = 11.21VNGKK2645 pKa = 7.85PNRR2648 pKa = 11.84KK2649 pKa = 8.69IRR2651 pKa = 11.84PDD2653 pKa = 3.06NKK2655 pKa = 10.23LIRR2658 pKa = 11.84NITNLLEE2665 pKa = 4.07EE2666 pKa = 5.1LEE2668 pKa = 4.76AEE2670 pKa = 4.32DD2671 pKa = 3.59WQDD2674 pKa = 2.81RR2675 pKa = 11.84AMEE2678 pKa = 4.28IVEE2681 pKa = 4.02EE2682 pKa = 4.72AYY2684 pKa = 10.75SVMVQVINCLQGEE2697 pKa = 4.37IKK2699 pKa = 10.26KK2700 pKa = 10.83SKK2702 pKa = 10.18AKK2704 pKa = 10.07KK2705 pKa = 10.06FKK2707 pKa = 10.5ILMMTMGSSGDD2718 pKa = 3.35YY2719 pKa = 10.54KK2720 pKa = 10.64YY2721 pKa = 10.97FRR2723 pKa = 11.84NAALILNKK2731 pKa = 10.4AGAQTDD2737 pKa = 4.13YY2738 pKa = 10.96IVPHH2742 pKa = 6.85EE2743 pKa = 4.08GAKK2746 pKa = 9.52WFEE2749 pKa = 4.07EE2750 pKa = 4.33VGGKK2754 pKa = 9.54IYY2756 pKa = 9.94TCEE2759 pKa = 3.99YY2760 pKa = 9.73KK2761 pKa = 10.95VKK2763 pKa = 10.52EE2764 pKa = 4.79KK2765 pKa = 10.93LDD2767 pKa = 3.26NWDD2770 pKa = 3.22AARR2773 pKa = 11.84RR2774 pKa = 11.84WDD2776 pKa = 4.95LEE2778 pKa = 3.93ALLSGMAEE2786 pKa = 3.98GTEE2789 pKa = 4.14CLTTKK2794 pKa = 10.59RR2795 pKa = 11.84IQTEE2799 pKa = 4.25VFNNKK2804 pKa = 8.44YY2805 pKa = 11.21DD2806 pKa = 3.74MVIGTGITILGKK2818 pKa = 9.1TIAEE2822 pKa = 4.32YY2823 pKa = 9.64FACPYY2828 pKa = 10.24IEE2830 pKa = 5.85LNAQPWFVQLYY2841 pKa = 7.64THH2843 pKa = 7.71DD2844 pKa = 3.58EE2845 pKa = 4.19TLAGKK2850 pKa = 8.08TKK2852 pKa = 10.72GLLDD2856 pKa = 3.6KK2857 pKa = 10.34MGKK2860 pKa = 10.47ANVILANAKK2869 pKa = 10.09GIRR2872 pKa = 11.84DD2873 pKa = 3.71LRR2875 pKa = 11.84ANLQMPEE2882 pKa = 4.01GDD2884 pKa = 3.87LASDD2888 pKa = 3.98ALIDD2892 pKa = 3.72QPSIYY2897 pKa = 10.06CYY2899 pKa = 10.12EE2900 pKa = 4.46PCLSSDD2906 pKa = 3.23RR2907 pKa = 11.84MYY2909 pKa = 10.93EE2910 pKa = 3.59SWPIVGYY2917 pKa = 10.18LGRR2920 pKa = 11.84SLIRR2924 pKa = 11.84KK2925 pKa = 7.56DD2926 pKa = 3.43QPEE2929 pKa = 4.21CQKK2932 pKa = 10.9YY2933 pKa = 10.84DD2934 pKa = 3.07IVFTMGSMVSKK2945 pKa = 10.43NIPIHH2950 pKa = 6.6AEE2952 pKa = 3.81TVMSYY2957 pKa = 10.64SKK2959 pKa = 10.53KK2960 pKa = 9.95HH2961 pKa = 5.5KK2962 pKa = 10.49LKK2964 pKa = 9.65TLILGGYY2971 pKa = 9.3SSDD2974 pKa = 4.19KK2975 pKa = 10.59IKK2977 pKa = 10.39PLHH2980 pKa = 6.89DD2981 pKa = 3.93KK2982 pKa = 10.93LSEE2985 pKa = 3.92RR2986 pKa = 11.84DD2987 pKa = 3.12KK2988 pKa = 11.31EE2989 pKa = 4.31LIHH2992 pKa = 6.68FEE2994 pKa = 4.29VYY2996 pKa = 10.53AEE2998 pKa = 4.65HH2999 pKa = 7.14EE3000 pKa = 4.34DD3001 pKa = 3.77VMTEE3005 pKa = 3.78RR3006 pKa = 11.84TIVIHH3011 pKa = 6.76HH3012 pKa = 6.83GGCGTTNQALIGGCPQVIITVAFDD3036 pKa = 3.09QFYY3039 pKa = 8.97WAHH3042 pKa = 6.5KK3043 pKa = 10.44AKK3045 pKa = 10.62LCGISEE3051 pKa = 4.23HH3052 pKa = 6.51MDD3054 pKa = 2.86VDD3056 pKa = 4.12EE3057 pKa = 5.03PTDD3060 pKa = 4.12LLPGLITKK3068 pKa = 9.7LRR3070 pKa = 11.84SEE3072 pKa = 5.09SYY3074 pKa = 9.47AQAAIMMKK3082 pKa = 8.92TRR3084 pKa = 11.84LVTGVAKK3091 pKa = 10.64NLIIGLRR3098 pKa = 11.84SLATQMDD3105 pKa = 4.39MLRR3108 pKa = 11.84TNPSTYY3114 pKa = 10.72EE3115 pKa = 4.08KK3116 pKa = 9.31ITNLSPPLDD3125 pKa = 3.55QEE3127 pKa = 4.22IFSSKK3132 pKa = 10.54SLPQRR3137 pKa = 11.84PAITTQGPTFTDD3149 pKa = 3.47DD3150 pKa = 3.5VPNKK3154 pKa = 10.27SKK3156 pKa = 10.88YY3157 pKa = 10.14FKK3159 pKa = 10.38LQEE3162 pKa = 3.93EE3163 pKa = 4.9MKK3165 pKa = 10.58PLMKK3169 pKa = 10.08EE3170 pKa = 3.63WNFEE3174 pKa = 3.5ITEE3177 pKa = 4.08PRR3179 pKa = 11.84RR3180 pKa = 11.84IHH3182 pKa = 4.89YY3183 pKa = 6.94TCCGSYY3189 pKa = 11.08GSIDD3193 pKa = 3.25VTLAEE3198 pKa = 4.64NSDD3201 pKa = 3.69TLIVCNLEE3209 pKa = 4.02NVRR3212 pKa = 11.84KK3213 pKa = 9.1PRR3215 pKa = 11.84FVYY3218 pKa = 9.63VAKK3221 pKa = 9.89EE3222 pKa = 3.67HH3223 pKa = 6.57TIIQPVLPFDD3233 pKa = 4.23TNRR3236 pKa = 11.84GPPSTATLAYY3246 pKa = 8.81HH3247 pKa = 6.11AHH3249 pKa = 6.5GEE3251 pKa = 4.1ILHH3254 pKa = 6.14EE3255 pKa = 4.08QMKK3258 pKa = 9.77PYY3260 pKa = 10.16KK3261 pKa = 9.18ATEE3264 pKa = 3.85IKK3266 pKa = 9.58TLAGQEE3272 pKa = 4.08QIISEE3277 pKa = 4.6SKK3279 pKa = 7.9WLYY3282 pKa = 9.69YY3283 pKa = 9.89AAKK3286 pKa = 8.61NTRR3289 pKa = 11.84KK3290 pKa = 9.92VDD3292 pKa = 3.11TDD3294 pKa = 3.56YY3295 pKa = 11.82GNKK3298 pKa = 9.85RR3299 pKa = 11.84NGRR3302 pKa = 11.84GIDD3305 pKa = 3.29CRR3307 pKa = 11.84ICYY3310 pKa = 9.5RR3311 pKa = 11.84RR3312 pKa = 11.84GWKK3315 pKa = 9.49AHH3317 pKa = 7.11PDD3319 pKa = 3.35LDD3321 pKa = 3.8ICTCCFSKK3329 pKa = 11.33LEE3331 pKa = 4.18FPQIGNTADD3340 pKa = 3.19EE3341 pKa = 4.39EE3342 pKa = 4.74TIKK3345 pKa = 10.69KK3346 pKa = 8.1YY3347 pKa = 9.49TILKK3351 pKa = 10.0EE3352 pKa = 4.21GGLNRR3357 pKa = 11.84QNQFQAGIGNALSLTTSVPQLSVGLYY3383 pKa = 8.53HH3384 pKa = 6.82GKK3386 pKa = 10.22SYY3388 pKa = 10.82GYY3390 pKa = 7.85STKK3393 pKa = 10.18FNPQGPDD3400 pKa = 3.05GCVKK3404 pKa = 10.49KK3405 pKa = 10.7CIQAYY3410 pKa = 10.31VDD3412 pKa = 4.51LNTEE3416 pKa = 3.69ATRR3419 pKa = 11.84PVMKK3423 pKa = 10.49NNRR3426 pKa = 11.84LTLIQDD3432 pKa = 3.34QPSIIVEE3439 pKa = 4.5EE3440 pKa = 3.99ILKK3443 pKa = 8.16TFNMPSMTPLEE3454 pKa = 4.73HH3455 pKa = 7.06IEE3457 pKa = 4.44PYY3459 pKa = 10.36CHH3461 pKa = 7.62LLGLSTTLVIKK3472 pKa = 10.66GNVRR3476 pKa = 11.84VTVLPDD3482 pKa = 4.5AIGHH3486 pKa = 6.08IEE3488 pKa = 4.15LLIIQTNKK3496 pKa = 10.3LLHH3499 pKa = 6.29CVLVTMNPAYY3509 pKa = 10.81LEE3511 pKa = 3.88TLIRR3515 pKa = 11.84QEE3517 pKa = 4.37TPRR3520 pKa = 11.84LSCTVQNSDD3529 pKa = 5.01SLTTCQICEE3538 pKa = 3.96QQTIDD3543 pKa = 3.17IKK3545 pKa = 10.82AGKK3548 pKa = 8.62GLRR3551 pKa = 11.84VSTQGKK3557 pKa = 8.51CHH3559 pKa = 6.33GLHH3562 pKa = 6.74AEE3564 pKa = 3.69WDD3566 pKa = 4.1RR3567 pKa = 11.84YY3568 pKa = 10.28LVACRR3573 pKa = 11.84RR3574 pKa = 11.84MIMGEE3579 pKa = 4.09MVDD3582 pKa = 3.09RR3583 pKa = 11.84GYY3585 pKa = 10.69WSDD3588 pKa = 2.81KK3589 pKa = 8.49TANHH3593 pKa = 6.0VKK3595 pKa = 10.16SVHH3598 pKa = 5.6QRR3600 pKa = 11.84ITLEE3604 pKa = 4.38KK3605 pKa = 7.74ITHH3608 pKa = 5.69VFRR3611 pKa = 11.84SMTEE3615 pKa = 3.67PVIFSPLSTGNDD3627 pKa = 3.32YY3628 pKa = 11.52IMIEE3632 pKa = 4.19KK3633 pKa = 9.39PQTIKK3638 pKa = 10.57PGQVMIANTEE3648 pKa = 3.68KK3649 pKa = 11.0GIIIGHH3655 pKa = 5.18TLQYY3659 pKa = 9.53KK3660 pKa = 9.83DD3661 pKa = 4.68RR3662 pKa = 11.84MMLVHH3667 pKa = 6.51NMGIVEE3673 pKa = 4.52PLSQAVINLRR3683 pKa = 11.84TTTLPRR3689 pKa = 11.84DD3690 pKa = 4.0YY3691 pKa = 10.91DD3692 pKa = 4.14PKK3694 pKa = 10.93DD3695 pKa = 3.23TDD3697 pKa = 3.04QGKK3700 pKa = 8.99EE3701 pKa = 3.77VTSYY3705 pKa = 11.77NLATRR3710 pKa = 11.84QTMEE3714 pKa = 3.97QIDD3717 pKa = 3.99YY3718 pKa = 10.29NLRR3721 pKa = 11.84YY3722 pKa = 9.91LPISLKK3728 pKa = 9.92GMKK3731 pKa = 10.16VILTDD3736 pKa = 3.48LRR3738 pKa = 11.84NRR3740 pKa = 11.84NHH3742 pKa = 6.59HH3743 pKa = 5.65NEE3745 pKa = 3.62IVAVNIEE3752 pKa = 4.14KK3753 pKa = 10.53ARR3755 pKa = 11.84QFLVDD3760 pKa = 3.44QTMKK3764 pKa = 10.32PLEE3767 pKa = 4.34PEE3769 pKa = 4.14VIEE3772 pKa = 4.1SLKK3775 pKa = 10.59YY3776 pKa = 10.37NGPIVLGLKK3785 pKa = 10.05NGRR3788 pKa = 11.84LEE3790 pKa = 4.14YY3791 pKa = 10.35QHH3793 pKa = 6.65NLVASGPVSGSIIADD3808 pKa = 3.61VEE3810 pKa = 4.12KK3811 pKa = 10.63HH3812 pKa = 4.46LTGLISIKK3820 pKa = 10.16PLEE3823 pKa = 5.14KK3824 pKa = 8.99IDD3826 pKa = 3.7KK3827 pKa = 10.51LKK3829 pKa = 10.21TINPNMFRR3837 pKa = 11.84CLGNEE3842 pKa = 3.78WTFEE3846 pKa = 4.13EE3847 pKa = 5.04YY3848 pKa = 10.28EE3849 pKa = 4.35SEE3851 pKa = 4.25LEE3853 pKa = 4.05KK3854 pKa = 11.13PEE3856 pKa = 3.92MGKK3859 pKa = 10.16DD3860 pKa = 2.9IKK3862 pKa = 11.11DD3863 pKa = 3.15IGEE3866 pKa = 4.13LRR3868 pKa = 11.84DD3869 pKa = 4.78LLMQPGWKK3877 pKa = 8.1TRR3879 pKa = 11.84LRR3881 pKa = 11.84VDD3883 pKa = 3.72QLTPDD3888 pKa = 3.79NFPISLITRR3897 pKa = 11.84GAVIKK3902 pKa = 10.67NAMRR3906 pKa = 11.84VDD3908 pKa = 3.72PGVEE3912 pKa = 3.68VAYY3915 pKa = 10.33RR3916 pKa = 11.84EE3917 pKa = 4.73HH3918 pKa = 7.05ILQVLVCEE3926 pKa = 4.56EE3927 pKa = 4.7DD3928 pKa = 3.5NLLLKK3933 pKa = 10.83DD3934 pKa = 3.81KK3935 pKa = 10.83LLEE3938 pKa = 4.39RR3939 pKa = 11.84DD3940 pKa = 3.19VDD3942 pKa = 4.44FKK3944 pKa = 11.56LQAAQDD3950 pKa = 4.22AIAEE3954 pKa = 4.31EE3955 pKa = 4.15KK3956 pKa = 10.5RR3957 pKa = 11.84RR3958 pKa = 11.84FEE3960 pKa = 3.99SRR3962 pKa = 11.84PFKK3965 pKa = 10.53TIINSEE3971 pKa = 4.18EE3972 pKa = 3.92TFEE3975 pKa = 4.28TVRR3978 pKa = 11.84LLRR3981 pKa = 11.84KK3982 pKa = 9.76RR3983 pKa = 11.84NTVVEE3988 pKa = 4.71TIQYY3992 pKa = 9.87QEE3994 pKa = 4.16YY3995 pKa = 9.93KK3996 pKa = 10.34QGLQAPVQEE4005 pKa = 4.53VDD4007 pKa = 3.12LTQDD4011 pKa = 3.45KK4012 pKa = 10.36RR4013 pKa = 11.84WEE4015 pKa = 4.32DD4016 pKa = 3.81MLSLRR4021 pKa = 11.84PPTNEE4026 pKa = 3.43VYY4028 pKa = 10.98VLTRR4032 pKa = 11.84PEE4034 pKa = 3.85STQMVRR4040 pKa = 11.84RR4041 pKa = 11.84LLEE4044 pKa = 4.33GKK4046 pKa = 7.99VTPQFDD4052 pKa = 3.82TVEE4055 pKa = 4.49GKK4057 pKa = 10.61VKK4059 pKa = 10.21LHH4061 pKa = 5.74VMAPNPTSEE4070 pKa = 5.49FIDD4073 pKa = 4.14LNLDD4077 pKa = 3.77YY4078 pKa = 11.84YY4079 pKa = 10.62MGTHH4083 pKa = 7.39KK4084 pKa = 11.01YY4085 pKa = 9.54QDD4087 pKa = 3.89NIEE4090 pKa = 4.06GLMEE4094 pKa = 4.61SVIQMDD4100 pKa = 4.36DD4101 pKa = 3.29AGQLTSDD4108 pKa = 3.28MHH4110 pKa = 7.88KK4111 pKa = 10.56LVTVPSTLGHH4121 pKa = 5.59VKK4123 pKa = 10.35NLARR4127 pKa = 11.84LTGVPEE4133 pKa = 4.13TPEE4136 pKa = 4.07LAKK4139 pKa = 10.62LAAAILEE4146 pKa = 4.28ANGRR4150 pKa = 11.84KK4151 pKa = 9.8GKK4153 pKa = 6.03TTSHH4157 pKa = 6.2RR4158 pKa = 11.84MVLEE4162 pKa = 4.14DD4163 pKa = 4.07LGEE4166 pKa = 4.28EE4167 pKa = 4.22EE4168 pKa = 5.42LVQLLVPEE4176 pKa = 4.79DD4177 pKa = 3.56PVVIDD4182 pKa = 3.29KK4183 pKa = 10.94SIYY4186 pKa = 9.6SKK4188 pKa = 10.69IGGAVYY4194 pKa = 10.22KK4195 pKa = 9.92PASLVGFGLKK4205 pKa = 10.34DD4206 pKa = 3.6FQKK4209 pKa = 10.77EE4210 pKa = 3.98ALTTRR4215 pKa = 11.84QFWNEE4220 pKa = 3.49NEE4222 pKa = 4.39TKK4224 pKa = 10.47GKK4226 pKa = 10.54YY4227 pKa = 9.99KK4228 pKa = 9.79LTEE4231 pKa = 3.87TMTVEE4236 pKa = 5.51GYY4238 pKa = 11.0NKK4240 pKa = 9.99LHH4242 pKa = 6.41SNKK4245 pKa = 8.33PTIPVNVTSQGQHH4258 pKa = 4.37STSTQTNITTQTTEE4272 pKa = 3.86KK4273 pKa = 10.6EE4274 pKa = 4.04ILEE4277 pKa = 4.37KK4278 pKa = 11.02YY4279 pKa = 7.82ATNEE4283 pKa = 4.35PIVVNQDD4290 pKa = 2.72TVTKK4294 pKa = 9.17YY4295 pKa = 11.0RR4296 pKa = 11.84SMKK4299 pKa = 9.33PNYY4302 pKa = 9.44VEE4304 pKa = 4.33PGCLEE4309 pKa = 3.96TEE4311 pKa = 4.29YY4312 pKa = 11.19VKK4314 pKa = 10.87PRR4316 pKa = 11.84DD4317 pKa = 3.69ITTDD4321 pKa = 3.01AHH4323 pKa = 6.46DD4324 pKa = 4.0SSVKK4328 pKa = 10.3EE4329 pKa = 4.32GEE4331 pKa = 3.88ALGIINTNWMEE4342 pKa = 3.91EE4343 pKa = 4.08DD4344 pKa = 3.83KK4345 pKa = 11.21LLEE4348 pKa = 4.46LLDD4351 pKa = 3.81STTEE4355 pKa = 4.05DD4356 pKa = 3.07KK4357 pKa = 11.32SAGLWVEE4364 pKa = 4.32KK4365 pKa = 10.89VDD4367 pKa = 3.9MDD4369 pKa = 4.03HH4370 pKa = 7.18KK4371 pKa = 11.1LVAEE4375 pKa = 4.51DD4376 pKa = 4.22MNDD4379 pKa = 3.59KK4380 pKa = 11.05INVFTINFFEE4390 pKa = 5.3DD4391 pKa = 3.04NDD4393 pKa = 3.84MTDD4396 pKa = 3.89FNMMVAPTQGVLKK4409 pKa = 10.72SKK4411 pKa = 7.57EE4412 pKa = 4.33TPCRR4416 pKa = 11.84VMEE4419 pKa = 4.16TRR4421 pKa = 11.84KK4422 pKa = 8.56VTLTKK4427 pKa = 10.28RR4428 pKa = 11.84PTGSRR4433 pKa = 11.84PVFNKK4438 pKa = 10.01LANAEE4443 pKa = 4.07FMAVSRR4449 pKa = 11.84RR4450 pKa = 11.84LMSVVTMRR4458 pKa = 11.84KK4459 pKa = 8.62YY4460 pKa = 10.6QLDD4463 pKa = 3.89PKK4465 pKa = 10.21QEE4467 pKa = 3.59WDD4469 pKa = 3.36RR4470 pKa = 11.84FDD4472 pKa = 4.23RR4473 pKa = 11.84NYY4475 pKa = 10.54VSVMGKK4481 pKa = 9.83KK4482 pKa = 10.05LLRR4485 pKa = 11.84AYY4487 pKa = 9.76KK4488 pKa = 10.08EE4489 pKa = 3.73DD4490 pKa = 3.28QIYY4493 pKa = 10.35FNSEE4497 pKa = 4.36EE4498 pKa = 3.68IRR4500 pKa = 11.84KK4501 pKa = 8.74WISSRR4506 pKa = 11.84PDD4508 pKa = 2.93SVKK4511 pKa = 9.63IDD4513 pKa = 3.69RR4514 pKa = 11.84EE4515 pKa = 4.21LEE4517 pKa = 4.1EE4518 pKa = 3.99MLSTGFEE4525 pKa = 3.77INAINTAKK4533 pKa = 10.39VHH4535 pKa = 5.87VKK4537 pKa = 10.64LEE4539 pKa = 4.16SLLKK4543 pKa = 10.23EE4544 pKa = 4.58DD4545 pKa = 4.35YY4546 pKa = 10.61EE4547 pKa = 4.89SVGNRR4552 pKa = 11.84EE4553 pKa = 3.65IEE4555 pKa = 3.77HH4556 pKa = 7.02RR4557 pKa = 11.84IIVWQRR4563 pKa = 11.84KK4564 pKa = 5.77AWCAIFSPVFLQAKK4578 pKa = 9.52ARR4580 pKa = 11.84LKK4582 pKa = 10.75AILSRR4587 pKa = 11.84KK4588 pKa = 8.47VLYY4591 pKa = 10.67ADD4593 pKa = 4.36GLTQEE4598 pKa = 4.58EE4599 pKa = 4.67LSSRR4603 pKa = 11.84VNLIHH4608 pKa = 6.63GDD4610 pKa = 3.53CWFMEE4615 pKa = 5.02DD4616 pKa = 5.63DD4617 pKa = 4.6LSKK4620 pKa = 10.68QDD4622 pKa = 3.38RR4623 pKa = 11.84QTDD4626 pKa = 3.22INLIQCEE4633 pKa = 4.3MYY4635 pKa = 10.0IYY4637 pKa = 10.28SQLGVADD4644 pKa = 4.4DD4645 pKa = 4.52VLNLWRR4651 pKa = 11.84RR4652 pKa = 11.84THH4654 pKa = 6.17EE4655 pKa = 3.65NWKK4658 pKa = 10.17FRR4660 pKa = 11.84GTNVSGILTGMRR4672 pKa = 11.84LTGQATTAVGNAIVNLLVHH4691 pKa = 6.19SRR4693 pKa = 11.84IFEE4696 pKa = 4.23TNKK4699 pKa = 9.87NHH4701 pKa = 6.81IEE4703 pKa = 3.93LMLLLGDD4710 pKa = 4.53DD4711 pKa = 3.95NLVISRR4717 pKa = 11.84NRR4719 pKa = 11.84IDD4721 pKa = 3.64SSKK4724 pKa = 10.43QSKK4727 pKa = 9.59ISKK4730 pKa = 9.75DD4731 pKa = 3.63YY4732 pKa = 11.09YY4733 pKa = 11.31NMVSKK4738 pKa = 10.85ASHH4741 pKa = 7.02DD4742 pKa = 3.77RR4743 pKa = 11.84DD4744 pKa = 3.14QGTFLQLLCYY4754 pKa = 10.28HH4755 pKa = 6.71NPQGVLEE4762 pKa = 4.71FGPDD4766 pKa = 3.91VIRR4769 pKa = 11.84LAQRR4773 pKa = 11.84YY4774 pKa = 7.11EE4775 pKa = 3.91VTNGVSEE4782 pKa = 4.66SNNHH4786 pKa = 4.97NMLARR4791 pKa = 11.84TMSYY4795 pKa = 11.14CMLIGKK4801 pKa = 7.58TMGTKK4806 pKa = 10.3AVVTKK4811 pKa = 10.46HH4812 pKa = 5.82GLPIDD4817 pKa = 4.53LKK4819 pKa = 7.47TTCSMASARR4828 pKa = 11.84RR4829 pKa = 11.84ACAIKK4834 pKa = 10.44RR4835 pKa = 11.84KK4836 pKa = 6.98MTLGEE4841 pKa = 4.07VEE4843 pKa = 4.51SYY4845 pKa = 10.85EE4846 pKa = 4.3SYY4848 pKa = 10.64LYY4850 pKa = 11.42RR4851 pKa = 11.84MMKK4854 pKa = 10.06DD4855 pKa = 3.37LKK4857 pKa = 8.15THH4859 pKa = 4.84TWIFKK4864 pKa = 10.28HH4865 pKa = 6.04LAA4867 pKa = 3.35

Molecular weight: 551.66 kDa
Isoelectric point according different methods:

Protein with the highest isoelectric point:

>tr|A0A2U8JGM0|A0A2U8JGM0_9VIRU Polyprotein OS=Helianthus annuus alphaendornavirus OX=2184469 PE=4 SV=1

MM1 pKa = 8.22DD2 pKa = 4.74ILKK5 pKa = 10.33KK6 pKa = 10.08EE7 pKa = 4.38PKK9 pKa = 9.76PKK11 pKa = 10.63GEE13 pKa = 4.02PSSIQHH19 pKa = 6.74AGDD22 pKa = 4.17GPPSVLNVGEE32 pKa = 3.88ILANINKK39 pKa = 9.39LVSARR44 pKa = 11.84DD45 pKa = 3.42RR46 pKa = 11.84RR47 pKa = 11.84RR48 pKa = 11.84QTLRR52 pKa = 11.84TKK54 pKa = 8.24TRR56 pKa = 11.84RR57 pKa = 11.84LTEE60 pKa = 3.94NNEE63 pKa = 3.93FNVKK67 pKa = 9.52VDD69 pKa = 3.02PHH71 pKa = 6.07FQPKK75 pKa = 9.17FVKK78 pKa = 10.47CVAGSNKK85 pKa = 9.51QSMKK89 pKa = 10.35KK90 pKa = 10.04SPHH93 pKa = 5.33KK94 pKa = 8.44WQHH97 pKa = 4.34NVMVFNTINLGKK109 pKa = 9.81RR110 pKa = 11.84DD111 pKa = 3.61PHH113 pKa = 6.56EE114 pKa = 4.22IANKK118 pKa = 9.48LLAYY122 pKa = 7.97GAPAKK127 pKa = 10.98VKK129 pKa = 10.25DD130 pKa = 4.32CQCASCVSVDD140 pKa = 3.53NQRR143 pKa = 11.84SKK145 pKa = 11.41VAINTQATLGMWSITKK161 pKa = 9.93DD162 pKa = 3.18PCALEE167 pKa = 4.92GIDD170 pKa = 3.91IIKK173 pKa = 10.06YY174 pKa = 8.56RR175 pKa = 11.84PKK177 pKa = 10.53AIHH180 pKa = 6.05QLLSTEE186 pKa = 3.91QEE188 pKa = 4.01FRR190 pKa = 11.84KK191 pKa = 8.15TLWDD195 pKa = 4.09FKK197 pKa = 11.16LEE199 pKa = 4.08KK200 pKa = 10.18TLDD203 pKa = 3.61EE204 pKa = 4.45VVTGKK209 pKa = 10.23DD210 pKa = 2.91QFKK213 pKa = 10.53AHH215 pKa = 6.29MRR217 pKa = 11.84RR218 pKa = 11.84QFTKK222 pKa = 10.13YY223 pKa = 9.36LKK225 pKa = 10.51KK226 pKa = 10.27FSGYY230 pKa = 9.95QGLITEE236 pKa = 5.44ALTQTTRR243 pKa = 11.84CVPWAQVYY251 pKa = 9.75DD252 pKa = 3.59IRR254 pKa = 11.84TGEE257 pKa = 3.87PLANQFSHH265 pKa = 7.15RR266 pKa = 11.84KK267 pKa = 5.46PTPEE271 pKa = 4.58EE272 pKa = 3.69RR273 pKa = 11.84TQMITCPHH281 pKa = 6.55CKK283 pKa = 8.85CTNSLIVPRR292 pKa = 11.84DD293 pKa = 3.82LKK295 pKa = 10.97PKK297 pKa = 10.54LVDD300 pKa = 3.96LTDD303 pKa = 3.82HH304 pKa = 7.0RR305 pKa = 11.84CGACGRR311 pKa = 11.84PFQEE315 pKa = 4.9QMHH318 pKa = 6.83DD319 pKa = 2.98PWAEE323 pKa = 3.6IFDD326 pKa = 4.15IFDD329 pKa = 3.25EE330 pKa = 4.83SINPNVGAQTEE341 pKa = 4.38MMKK344 pKa = 11.01LMGRR348 pKa = 11.84LDD350 pKa = 3.38MSEE353 pKa = 3.66IDD355 pKa = 3.49EE356 pKa = 5.65AYY358 pKa = 9.57TLMDD362 pKa = 3.39IAEE365 pKa = 4.24KK366 pKa = 10.63HH367 pKa = 5.34DD368 pKa = 3.46TRR370 pKa = 11.84LVKK373 pKa = 10.53SALSRR378 pKa = 11.84LQLDD382 pKa = 4.18LVDD385 pKa = 4.26VPLNMEE391 pKa = 4.03KK392 pKa = 10.66SKK394 pKa = 11.3LGVLDD399 pKa = 3.48QLFGGFEE406 pKa = 4.08FVPKK410 pKa = 10.05PGLVTDD416 pKa = 4.66TPLEE420 pKa = 4.11DD421 pKa = 3.33TFRR424 pKa = 11.84NAVMTMVKK432 pKa = 8.61KK433 pKa = 7.48TTMSEE438 pKa = 3.72GFYY441 pKa = 10.61WPDD444 pKa = 3.26AYY446 pKa = 10.78QKK448 pKa = 10.48PNSSRR453 pKa = 11.84LNVVNPYY460 pKa = 9.08QCCGSLEE467 pKa = 4.01CDD469 pKa = 2.63HH470 pKa = 7.04WIKK473 pKa = 11.13KK474 pKa = 7.42NTFITLEE481 pKa = 4.09SLSVGLNGILKK492 pKa = 9.4MIEE495 pKa = 4.02RR496 pKa = 11.84SGKK499 pKa = 8.02EE500 pKa = 3.46AWVCLPTEE508 pKa = 4.94GYY510 pKa = 9.82NPKK513 pKa = 10.19ADD515 pKa = 3.19SGQFEE520 pKa = 4.33GGEE523 pKa = 4.24THH525 pKa = 5.74YY526 pKa = 10.74HH527 pKa = 6.25LSGHH531 pKa = 5.05VMKK534 pKa = 9.81LTRR537 pKa = 11.84PGHH540 pKa = 6.67DD541 pKa = 3.15YY542 pKa = 11.57PMIVDD547 pKa = 3.36KK548 pKa = 10.93TDD550 pKa = 3.32YY551 pKa = 11.3EE552 pKa = 4.28NLTEE556 pKa = 4.55GDD558 pKa = 3.63IFHH561 pKa = 7.34GSTGTYY567 pKa = 7.85MATTILTGCGHH578 pKa = 7.29KK579 pKa = 10.56VRR581 pKa = 11.84IIKK584 pKa = 10.4KK585 pKa = 7.82VDD587 pKa = 3.66LNIGEE592 pKa = 5.36IIPKK596 pKa = 10.17LKK598 pKa = 8.57PTKK601 pKa = 10.26ARR603 pKa = 11.84PQTFKK608 pKa = 10.82IPTVLPGSLGSITGILTSSVKK629 pKa = 10.2EE630 pKa = 4.08VTVEE634 pKa = 3.77PTLLKK639 pKa = 10.82SLMIKK644 pKa = 10.5NLDD647 pKa = 3.29ASMTFAEE654 pKa = 4.32LLEE657 pKa = 4.41FGMAFSFTRR666 pKa = 11.84YY667 pKa = 9.28HH668 pKa = 6.7RR669 pKa = 11.84GEE671 pKa = 4.15KK672 pKa = 9.89VISYY676 pKa = 10.72QDD678 pKa = 3.39LTSTQVIDD686 pKa = 3.51HH687 pKa = 6.29CVIALILTRR696 pKa = 11.84RR697 pKa = 11.84AMAARR702 pKa = 11.84TMIVSATQKK711 pKa = 9.79NSVMEE716 pKa = 4.43VIQSAGLSVGMTTAVTLLEE735 pKa = 5.33GITNTTIKK743 pKa = 10.73SSLKK747 pKa = 8.86TLMSRR752 pKa = 11.84VDD754 pKa = 4.13AISVNSLRR762 pKa = 11.84VIGEE766 pKa = 4.0HH767 pKa = 6.25PVWDD771 pKa = 5.55DD772 pKa = 3.07IQRR775 pKa = 11.84WTTKK779 pKa = 8.88VTLSSYY785 pKa = 10.58RR786 pKa = 11.84IIDD789 pKa = 3.74YY790 pKa = 10.56RR791 pKa = 11.84PLRR794 pKa = 11.84ATIRR798 pKa = 11.84KK799 pKa = 8.31EE800 pKa = 4.01VTCPHH805 pKa = 5.85VLSVIEE811 pKa = 5.58QGDD814 pKa = 4.06QQCLCCGRR822 pKa = 11.84LARR825 pKa = 11.84SDD827 pKa = 3.54MCKK830 pKa = 10.51DD831 pKa = 4.19CSPCANKK838 pKa = 9.82EE839 pKa = 4.06HH840 pKa = 6.83ACSHH844 pKa = 5.96TCVHH848 pKa = 6.1DD849 pKa = 3.78HH850 pKa = 6.94KK851 pKa = 11.42GEE853 pKa = 4.13KK854 pKa = 9.72KK855 pKa = 10.35CLCCQLPSEE864 pKa = 4.68NKK866 pKa = 9.38VCTCCKK872 pKa = 8.68VHH874 pKa = 6.59YY875 pKa = 10.12SVADD879 pKa = 3.49MVGQPTKK886 pKa = 10.82KK887 pKa = 8.62PTKK890 pKa = 10.18KK891 pKa = 10.01PEE893 pKa = 3.82QPKK896 pKa = 10.02RR897 pKa = 11.84DD898 pKa = 3.63SSSKK902 pKa = 6.71QTKK905 pKa = 9.52PEE907 pKa = 3.93QKK909 pKa = 9.51PGPKK913 pKa = 8.8TRR915 pKa = 11.84EE916 pKa = 4.01EE917 pKa = 3.98EE918 pKa = 3.7QGQYY922 pKa = 10.68NDD924 pKa = 3.34EE925 pKa = 4.52DD926 pKa = 3.97EE927 pKa = 4.76VVIEE931 pKa = 3.83AAEE934 pKa = 4.2RR935 pKa = 11.84EE936 pKa = 4.2DD937 pKa = 5.5ALIQQTSLDD946 pKa = 3.95FVTALLSPEE955 pKa = 3.93AWPTEE960 pKa = 3.97ATKK963 pKa = 10.84NPPCGDD969 pKa = 2.99IPMGSRR975 pKa = 11.84ILYY978 pKa = 9.96VPMGLTIGEE987 pKa = 4.39SKK989 pKa = 10.3SVKK992 pKa = 8.64VTSHH996 pKa = 5.97KK997 pKa = 10.68VIPNKK1002 pKa = 10.51EE1003 pKa = 4.28GTCGLDD1009 pKa = 3.27ALRR1012 pKa = 11.84LGMGEE1017 pKa = 4.06QVTISVMEE1025 pKa = 4.14TVTKK1029 pKa = 9.28KK1030 pKa = 8.7TRR1032 pKa = 11.84GWDD1035 pKa = 3.27VDD1037 pKa = 4.19DD1038 pKa = 4.35LLKK1041 pKa = 10.91VGKK1044 pKa = 10.1ALGKK1048 pKa = 10.13NVLVLTGTEE1057 pKa = 3.94VHH1059 pKa = 6.04VMKK1062 pKa = 10.93SNSEE1066 pKa = 4.09DD1067 pKa = 3.53DD1068 pKa = 3.72YY1069 pKa = 11.27HH1070 pKa = 7.13TIIHH1074 pKa = 5.48STALNKK1080 pKa = 10.07EE1081 pKa = 4.15GQHH1084 pKa = 6.11WYY1086 pKa = 9.49PGTVQQVGVIRR1097 pKa = 11.84KK1098 pKa = 8.02EE1099 pKa = 3.89VVYY1102 pKa = 10.93NPTITMQTMHH1112 pKa = 7.55KK1113 pKa = 9.95IAQQVTRR1120 pKa = 11.84KK1121 pKa = 9.58KK1122 pKa = 9.88VNHH1125 pKa = 6.32YY1126 pKa = 10.47DD1127 pKa = 3.25VALMEE1132 pKa = 4.46RR1133 pKa = 11.84KK1134 pKa = 9.32EE1135 pKa = 4.72LIDD1138 pKa = 3.57LHH1140 pKa = 6.52VAAATVAEE1148 pKa = 4.63TIKK1151 pKa = 10.39IHH1153 pKa = 5.45TVVDD1157 pKa = 3.5KK1158 pKa = 11.34NFRR1161 pKa = 11.84LEE1163 pKa = 4.18TNQDD1167 pKa = 2.69EE1168 pKa = 4.68QYY1170 pKa = 11.33LVNNKK1175 pKa = 8.05EE1176 pKa = 3.83RR1177 pKa = 11.84EE1178 pKa = 4.02HH1179 pKa = 6.61NIRR1182 pKa = 11.84EE1183 pKa = 4.19GKK1185 pKa = 9.48ICVIVPTYY1193 pKa = 9.4LLSVIRR1199 pKa = 11.84HH1200 pKa = 5.43LTRR1203 pKa = 11.84LSPDD1207 pKa = 3.69SISNDD1212 pKa = 3.23DD1213 pKa = 3.5VNTIFDD1219 pKa = 4.52KK1220 pKa = 10.94DD1221 pKa = 3.75DD1222 pKa = 4.2QIPEE1226 pKa = 4.33TLNAWIKK1233 pKa = 11.16SEE1235 pKa = 4.25VADD1238 pKa = 3.83CVKK1241 pKa = 10.24TILYY1245 pKa = 8.76ALCYY1249 pKa = 10.25DD1250 pKa = 4.88VIPKK1254 pKa = 8.41STNPLRR1260 pKa = 11.84ITYY1263 pKa = 9.09EE1264 pKa = 4.2KK1265 pKa = 10.73FDD1267 pKa = 4.39MIQDD1271 pKa = 3.96GTRR1274 pKa = 11.84TVLDD1278 pKa = 3.37VSRR1281 pKa = 11.84TKK1283 pKa = 10.81LKK1285 pKa = 10.83SLDD1288 pKa = 3.74VIYY1291 pKa = 10.28LHH1293 pKa = 6.71QDD1295 pKa = 2.95GKK1297 pKa = 10.7IVPTMINPKK1306 pKa = 8.42MGKK1309 pKa = 9.16IAITTDD1315 pKa = 2.39KK1316 pKa = 10.83SYY1318 pKa = 11.08RR1319 pKa = 11.84NKK1321 pKa = 10.61GMTIGIPQISIGSAIRR1337 pKa = 11.84NLASLLTMNTQSTYY1351 pKa = 11.73AMSKK1355 pKa = 10.78LEE1357 pKa = 4.19DD1358 pKa = 3.73SVMVLAPPGAGKK1370 pKa = 7.2TTEE1373 pKa = 3.72IMKK1376 pKa = 10.62LLTEE1380 pKa = 4.23SSLVVASTGGALNSLRR1396 pKa = 11.84QKK1398 pKa = 10.71KK1399 pKa = 9.43PPCQVLSVEE1408 pKa = 4.13AGKK1411 pKa = 10.47NYY1413 pKa = 10.2DD1414 pKa = 3.66LQVDD1418 pKa = 3.71HH1419 pKa = 6.97LVIDD1423 pKa = 3.77EE1424 pKa = 4.31CTTVGFLDD1432 pKa = 3.73YY1433 pKa = 10.73KK1434 pKa = 11.17AIVDD1438 pKa = 3.61KK1439 pKa = 11.25VKK1441 pKa = 10.15PKK1443 pKa = 10.59KK1444 pKa = 10.62VFAFGDD1450 pKa = 3.64TSQIGLKK1457 pKa = 10.36DD1458 pKa = 3.41MRR1460 pKa = 11.84ISAGTRR1466 pKa = 11.84AIQGLNTYY1474 pKa = 9.52HH1475 pKa = 7.78KK1476 pKa = 10.41SIKK1479 pKa = 9.82KK1480 pKa = 9.98LNHH1483 pKa = 5.95TYY1485 pKa = 10.69RR1486 pKa = 11.84IGQPLSNVLSEE1497 pKa = 4.5VYY1499 pKa = 10.7NDD1501 pKa = 4.16LEE1503 pKa = 4.51SKK1505 pKa = 10.87AEE1507 pKa = 3.95HH1508 pKa = 5.94KK1509 pKa = 9.79TDD1511 pKa = 5.16FEE1513 pKa = 5.35VIWSSHH1519 pKa = 5.62FDD1521 pKa = 3.49PEE1523 pKa = 4.47TVYY1526 pKa = 11.12EE1527 pKa = 4.39KK1528 pKa = 10.87ALKK1531 pKa = 10.24HH1532 pKa = 6.07NYY1534 pKa = 9.71DD1535 pKa = 4.05VILVHH1540 pKa = 6.05YY1541 pKa = 9.07RR1542 pKa = 11.84SHH1544 pKa = 7.23KK1545 pKa = 10.47AALLQQLNIIARR1557 pKa = 11.84GNTPLAQWARR1567 pKa = 11.84RR1568 pKa = 11.84VRR1570 pKa = 11.84VEE1572 pKa = 4.64TIHH1575 pKa = 6.92SYY1577 pKa = 10.34QGQEE1581 pKa = 3.48ADD1583 pKa = 3.07KK1584 pKa = 11.39VMVIQRR1590 pKa = 11.84SNQAGGSIEE1599 pKa = 5.54FDD1601 pKa = 3.14PQYY1604 pKa = 10.9NISAASRR1611 pKa = 11.84AKK1613 pKa = 10.44KK1614 pKa = 9.79HH1615 pKa = 5.05LTWYY1619 pKa = 10.34AVGVHH1624 pKa = 5.91SPNVDD1629 pKa = 2.85LGTILRR1635 pKa = 11.84PSKK1638 pKa = 10.94NIVGYY1643 pKa = 10.46GLFDD1647 pKa = 3.32MFSRR1651 pKa = 11.84FHH1653 pKa = 6.95TDD1655 pKa = 3.82TIQEE1659 pKa = 4.39SVKK1662 pKa = 10.38QPRR1665 pKa = 11.84LKK1667 pKa = 10.13KK1668 pKa = 9.87RR1669 pKa = 11.84KK1670 pKa = 9.36GIGRR1674 pKa = 11.84QFLKK1678 pKa = 10.27TINNYY1683 pKa = 9.86LDD1685 pKa = 3.46RR1686 pKa = 11.84KK1687 pKa = 9.28YY1688 pKa = 10.84KK1689 pKa = 9.54ATATLVEE1696 pKa = 4.18THH1698 pKa = 6.59DD1699 pKa = 4.73RR1700 pKa = 11.84EE1701 pKa = 4.19VLKK1704 pKa = 10.79IKK1706 pKa = 10.78VSVITMAEE1714 pKa = 4.01VTISADD1720 pKa = 3.43GTIKK1724 pKa = 10.7EE1725 pKa = 4.19GLNRR1729 pKa = 11.84VGDD1732 pKa = 4.2LSQLIDD1738 pKa = 5.12LIHH1741 pKa = 7.09SNLEE1745 pKa = 4.12DD1746 pKa = 4.37KK1747 pKa = 9.87PTMTCSCNTISKK1759 pKa = 9.68IPSHH1763 pKa = 5.8KK1764 pKa = 9.66TMNQLEE1770 pKa = 4.62FNTCLRR1776 pKa = 11.84LCNLNWVACEE1786 pKa = 3.57MAMVGEE1792 pKa = 4.32TLRR1795 pKa = 11.84LAVGDD1800 pKa = 3.82KK1801 pKa = 10.92LYY1803 pKa = 11.26DD1804 pKa = 3.51FVNPGEE1810 pKa = 4.2CHH1812 pKa = 5.59VCSKK1816 pKa = 7.63TTIVHH1821 pKa = 5.64QEE1823 pKa = 3.95TEE1825 pKa = 3.76IVRR1828 pKa = 11.84INRR1831 pKa = 11.84SHH1833 pKa = 7.0HH1834 pKa = 5.0FHH1836 pKa = 6.67TDD1838 pKa = 2.59VSIEE1842 pKa = 3.87YY1843 pKa = 10.08LIPEE1847 pKa = 4.15EE1848 pKa = 4.03NLLVEE1853 pKa = 5.62HH1854 pKa = 7.0FDD1856 pKa = 4.13LMNNLGLDD1864 pKa = 3.62EE1865 pKa = 3.93QLITHH1870 pKa = 6.52EE1871 pKa = 4.6RR1872 pKa = 11.84RR1873 pKa = 11.84PVDD1876 pKa = 3.61SPLLTRR1882 pKa = 11.84LANTEE1887 pKa = 4.06LTINTYY1893 pKa = 8.99VLQMRR1898 pKa = 11.84KK1899 pKa = 9.98SIEE1902 pKa = 4.07TTLKK1906 pKa = 9.03RR1907 pKa = 11.84TGNFIVDD1914 pKa = 3.53SLFGLKK1920 pKa = 10.16HH1921 pKa = 4.79EE1922 pKa = 5.29TIDD1925 pKa = 4.76SEE1927 pKa = 4.61TWCQSRR1933 pKa = 11.84GLTCLATIGNEE1944 pKa = 3.61MSRR1947 pKa = 11.84LVKK1950 pKa = 10.73VEE1952 pKa = 3.43VDD1954 pKa = 3.16NRR1956 pKa = 11.84IALMLPIEE1964 pKa = 5.21DD1965 pKa = 4.16SPIHH1969 pKa = 5.47YY1970 pKa = 10.41LEE1972 pKa = 4.74EE1973 pKa = 3.94EE1974 pKa = 4.4GKK1976 pKa = 10.42RR1977 pKa = 11.84DD1978 pKa = 4.02DD1979 pKa = 3.7NCKK1982 pKa = 9.72TMEE1985 pKa = 4.31EE1986 pKa = 4.62FIMEE1990 pKa = 4.54YY1991 pKa = 10.32INTLNTDD1998 pKa = 3.47GLLTKK2003 pKa = 9.85MISILGQMKK2012 pKa = 10.46VGGRR2016 pKa = 11.84DD2017 pKa = 3.33DD2018 pKa = 4.14LVNFEE2023 pKa = 4.54GLMVPYY2029 pKa = 9.07EE2030 pKa = 3.72RR2031 pKa = 11.84HH2032 pKa = 4.87MARR2035 pKa = 11.84KK2036 pKa = 9.51DD2037 pKa = 4.03RR2038 pKa = 11.84VWHH2041 pKa = 4.94TVVNKK2046 pKa = 9.89LGKK2049 pKa = 9.69MYY2051 pKa = 10.75VEE2053 pKa = 4.68SKK2055 pKa = 10.42RR2056 pKa = 11.84GEE2058 pKa = 3.94DD2059 pKa = 3.48SILYY2063 pKa = 10.24LSQTQIRR2070 pKa = 11.84EE2071 pKa = 3.7QGRR2074 pKa = 11.84LIKK2077 pKa = 10.35QQFPHH2082 pKa = 6.65LAINEE2087 pKa = 4.2HH2088 pKa = 6.89RR2089 pKa = 11.84YY2090 pKa = 9.65MMDD2093 pKa = 2.89SDD2095 pKa = 5.6DD2096 pKa = 4.09YY2097 pKa = 11.81GSTLEE2102 pKa = 3.79QLINHH2107 pKa = 6.0VLLNDD2112 pKa = 3.64SVGKK2116 pKa = 10.19VDD2118 pKa = 3.53YY2119 pKa = 9.65VTYY2122 pKa = 10.28RR2123 pKa = 11.84PHH2125 pKa = 8.5LVILNSRR2132 pKa = 11.84INCRR2136 pKa = 11.84LVEE2139 pKa = 4.32PNHH2142 pKa = 5.88NRR2144 pKa = 11.84LLTARR2149 pKa = 11.84SKK2151 pKa = 10.78INEE2154 pKa = 4.03TFMEE2158 pKa = 4.94GMCRR2162 pKa = 11.84NVEE2165 pKa = 3.99EE2166 pKa = 5.69AILTMASEE2174 pKa = 4.22NEE2176 pKa = 3.79KK2177 pKa = 11.16DD2178 pKa = 3.52EE2179 pKa = 4.49LVAITKK2185 pKa = 10.1QKK2187 pKa = 11.19LEE2189 pKa = 4.2LAQKK2193 pKa = 10.32CIRR2196 pKa = 11.84QKK2198 pKa = 10.31QGNWHH2203 pKa = 6.46PSKK2206 pKa = 9.84TFSKK2210 pKa = 10.07DD2211 pKa = 2.54TDD2213 pKa = 4.77LICLGEE2219 pKa = 4.7CGLSYY2224 pKa = 10.68EE2225 pKa = 4.42PSQLAQLVMEE2235 pKa = 4.27NSGRR2239 pKa = 11.84RR2240 pKa = 11.84IIIWGPNPALAKK2252 pKa = 10.17LDD2254 pKa = 3.61QLEE2257 pKa = 4.51VEE2259 pKa = 4.34GQEE2262 pKa = 4.14YY2263 pKa = 11.0LNVVDD2268 pKa = 5.15KK2269 pKa = 10.56RR2270 pKa = 11.84TGGHH2274 pKa = 5.92YY2275 pKa = 9.9IIHH2278 pKa = 5.96SGIWDD2283 pKa = 3.53SMKK2286 pKa = 10.7YY2287 pKa = 10.21GLPIAQEE2294 pKa = 4.19EE2295 pKa = 4.52KK2296 pKa = 10.37TSVLLASYY2304 pKa = 7.49MTIGGLIVYY2313 pKa = 8.36DD2314 pKa = 3.88VKK2316 pKa = 10.69IKK2318 pKa = 10.55RR2319 pKa = 11.84PQDD2322 pKa = 3.22IEE2324 pKa = 4.39LSWFAPLDD2332 pKa = 3.73SSKK2335 pKa = 8.17TTGLITIEE2343 pKa = 4.16VPHH2346 pKa = 6.56IHH2348 pKa = 6.95RR2349 pKa = 11.84DD2350 pKa = 3.5VVKK2353 pKa = 10.12LAKK2356 pKa = 10.0EE2357 pKa = 3.96GVPIISTRR2365 pKa = 11.84RR2366 pKa = 11.84IVADD2370 pKa = 3.61ARR2372 pKa = 11.84LLSNLAKK2379 pKa = 10.54RR2380 pKa = 11.84MLRR2383 pKa = 11.84PTTFDD2388 pKa = 2.99EE2389 pKa = 4.42LLNYY2393 pKa = 10.23ARR2395 pKa = 11.84VLAHH2399 pKa = 6.68GKK2401 pKa = 9.74HH2402 pKa = 5.6YY2403 pKa = 10.34SLKK2406 pKa = 10.23GFTSVYY2412 pKa = 10.56EE2413 pKa = 4.07EE2414 pKa = 4.62TPQEE2418 pKa = 3.96LLDD2421 pKa = 3.54ITMGVYY2427 pKa = 10.94LIYY2430 pKa = 10.83SRR2432 pKa = 11.84TIEE2435 pKa = 4.19SMEE2438 pKa = 3.74GMTEE2442 pKa = 4.39GIISRR2447 pKa = 11.84RR2448 pKa = 11.84DD2449 pKa = 3.09QDD2451 pKa = 4.01LDD2453 pKa = 3.44TFKK2456 pKa = 11.15AVLTEE2461 pKa = 4.22RR2462 pKa = 11.84VADD2465 pKa = 4.93FKK2467 pKa = 11.02TGLLGLVSKK2476 pKa = 9.2YY2477 pKa = 9.39TGLDD2481 pKa = 3.18LDD2483 pKa = 4.03LSDD2486 pKa = 3.92WLRR2489 pKa = 11.84ILSSGSRR2496 pKa = 11.84DD2497 pKa = 3.42HH2498 pKa = 7.2LSVIRR2503 pKa = 11.84QMITTLKK2510 pKa = 8.48HH2511 pKa = 4.13TRR2513 pKa = 11.84ARR2515 pKa = 11.84LLDD2518 pKa = 3.45DD2519 pKa = 3.46TRR2521 pKa = 11.84NIFPRR2526 pKa = 11.84PTVGSAPEE2534 pKa = 3.89SKK2536 pKa = 9.75IEE2538 pKa = 4.51KK2539 pKa = 9.58KK2540 pKa = 10.51DD2541 pKa = 3.44YY2542 pKa = 10.9SNNPFRR2548 pKa = 11.84FLEE2551 pKa = 4.0LAIDD2555 pKa = 3.91NVKK2558 pKa = 10.65ALAKK2562 pKa = 9.51LTFDD2566 pKa = 3.5NTHH2569 pKa = 6.19GSFKK2573 pKa = 10.3TATKK2577 pKa = 9.59PAIDD2581 pKa = 3.25KK2582 pKa = 9.04VVPQRR2587 pKa = 11.84RR2588 pKa = 11.84IADD2591 pKa = 3.46SHH2593 pKa = 6.07PTSDD2597 pKa = 3.94YY2598 pKa = 11.31LNMIEE2603 pKa = 4.36KK2604 pKa = 10.36SAMLTYY2610 pKa = 10.57QKK2612 pKa = 10.33FQQLPEE2618 pKa = 3.93FDD2620 pKa = 3.49YY2621 pKa = 11.93GEE2623 pKa = 4.3AYY2625 pKa = 9.52KK2626 pKa = 10.59KK2627 pKa = 10.73KK2628 pKa = 10.35LMEE2631 pKa = 4.22FQEE2634 pKa = 4.4VLEE2637 pKa = 4.35HH2638 pKa = 6.26AKK2640 pKa = 10.26KK2641 pKa = 11.21VNGKK2645 pKa = 7.85PNRR2648 pKa = 11.84KK2649 pKa = 8.69IRR2651 pKa = 11.84PDD2653 pKa = 3.06NKK2655 pKa = 10.23LIRR2658 pKa = 11.84NITNLLEE2665 pKa = 4.07EE2666 pKa = 5.1LEE2668 pKa = 4.76AEE2670 pKa = 4.32DD2671 pKa = 3.59WQDD2674 pKa = 2.81RR2675 pKa = 11.84AMEE2678 pKa = 4.28IVEE2681 pKa = 4.02EE2682 pKa = 4.72AYY2684 pKa = 10.75SVMVQVINCLQGEE2697 pKa = 4.37IKK2699 pKa = 10.26KK2700 pKa = 10.83SKK2702 pKa = 10.18AKK2704 pKa = 10.07KK2705 pKa = 10.06FKK2707 pKa = 10.5ILMMTMGSSGDD2718 pKa = 3.35YY2719 pKa = 10.54KK2720 pKa = 10.64YY2721 pKa = 10.97FRR2723 pKa = 11.84NAALILNKK2731 pKa = 10.4AGAQTDD2737 pKa = 4.13YY2738 pKa = 10.96IVPHH2742 pKa = 6.85EE2743 pKa = 4.08GAKK2746 pKa = 9.52WFEE2749 pKa = 4.07EE2750 pKa = 4.33VGGKK2754 pKa = 9.54IYY2756 pKa = 9.94TCEE2759 pKa = 3.99YY2760 pKa = 9.73KK2761 pKa = 10.95VKK2763 pKa = 10.52EE2764 pKa = 4.79KK2765 pKa = 10.93LDD2767 pKa = 3.26NWDD2770 pKa = 3.22AARR2773 pKa = 11.84RR2774 pKa = 11.84WDD2776 pKa = 4.95LEE2778 pKa = 3.93ALLSGMAEE2786 pKa = 3.98GTEE2789 pKa = 4.14CLTTKK2794 pKa = 10.59RR2795 pKa = 11.84IQTEE2799 pKa = 4.25VFNNKK2804 pKa = 8.44YY2805 pKa = 11.21DD2806 pKa = 3.74MVIGTGITILGKK2818 pKa = 9.1TIAEE2822 pKa = 4.32YY2823 pKa = 9.64FACPYY2828 pKa = 10.24IEE2830 pKa = 5.85LNAQPWFVQLYY2841 pKa = 7.64THH2843 pKa = 7.71DD2844 pKa = 3.58EE2845 pKa = 4.19TLAGKK2850 pKa = 8.08TKK2852 pKa = 10.72GLLDD2856 pKa = 3.6KK2857 pKa = 10.34MGKK2860 pKa = 10.47ANVILANAKK2869 pKa = 10.09GIRR2872 pKa = 11.84DD2873 pKa = 3.71LRR2875 pKa = 11.84ANLQMPEE2882 pKa = 4.01GDD2884 pKa = 3.87LASDD2888 pKa = 3.98ALIDD2892 pKa = 3.72QPSIYY2897 pKa = 10.06CYY2899 pKa = 10.12EE2900 pKa = 4.46PCLSSDD2906 pKa = 3.23RR2907 pKa = 11.84MYY2909 pKa = 10.93EE2910 pKa = 3.59SWPIVGYY2917 pKa = 10.18LGRR2920 pKa = 11.84SLIRR2924 pKa = 11.84KK2925 pKa = 7.56DD2926 pKa = 3.43QPEE2929 pKa = 4.21CQKK2932 pKa = 10.9YY2933 pKa = 10.84DD2934 pKa = 3.07IVFTMGSMVSKK2945 pKa = 10.43NIPIHH2950 pKa = 6.6AEE2952 pKa = 3.81TVMSYY2957 pKa = 10.64SKK2959 pKa = 10.53KK2960 pKa = 9.95HH2961 pKa = 5.5KK2962 pKa = 10.49LKK2964 pKa = 9.65TLILGGYY2971 pKa = 9.3SSDD2974 pKa = 4.19KK2975 pKa = 10.59IKK2977 pKa = 10.39PLHH2980 pKa = 6.89DD2981 pKa = 3.93KK2982 pKa = 10.93LSEE2985 pKa = 3.92RR2986 pKa = 11.84DD2987 pKa = 3.12KK2988 pKa = 11.31EE2989 pKa = 4.31LIHH2992 pKa = 6.68FEE2994 pKa = 4.29VYY2996 pKa = 10.53AEE2998 pKa = 4.65HH2999 pKa = 7.14EE3000 pKa = 4.34DD3001 pKa = 3.77VMTEE3005 pKa = 3.78RR3006 pKa = 11.84TIVIHH3011 pKa = 6.76HH3012 pKa = 6.83GGCGTTNQALIGGCPQVIITVAFDD3036 pKa = 3.09QFYY3039 pKa = 8.97WAHH3042 pKa = 6.5KK3043 pKa = 10.44AKK3045 pKa = 10.62LCGISEE3051 pKa = 4.23HH3052 pKa = 6.51MDD3054 pKa = 2.86VDD3056 pKa = 4.12EE3057 pKa = 5.03PTDD3060 pKa = 4.12LLPGLITKK3068 pKa = 9.7LRR3070 pKa = 11.84SEE3072 pKa = 5.09SYY3074 pKa = 9.47AQAAIMMKK3082 pKa = 8.92TRR3084 pKa = 11.84LVTGVAKK3091 pKa = 10.64NLIIGLRR3098 pKa = 11.84SLATQMDD3105 pKa = 4.39MLRR3108 pKa = 11.84TNPSTYY3114 pKa = 10.72EE3115 pKa = 4.08KK3116 pKa = 9.31ITNLSPPLDD3125 pKa = 3.55QEE3127 pKa = 4.22IFSSKK3132 pKa = 10.54SLPQRR3137 pKa = 11.84PAITTQGPTFTDD3149 pKa = 3.47DD3150 pKa = 3.5VPNKK3154 pKa = 10.27SKK3156 pKa = 10.88YY3157 pKa = 10.14FKK3159 pKa = 10.38LQEE3162 pKa = 3.93EE3163 pKa = 4.9MKK3165 pKa = 10.58PLMKK3169 pKa = 10.08EE3170 pKa = 3.63WNFEE3174 pKa = 3.5ITEE3177 pKa = 4.08PRR3179 pKa = 11.84RR3180 pKa = 11.84IHH3182 pKa = 4.89YY3183 pKa = 6.94TCCGSYY3189 pKa = 11.08GSIDD3193 pKa = 3.25VTLAEE3198 pKa = 4.64NSDD3201 pKa = 3.69TLIVCNLEE3209 pKa = 4.02NVRR3212 pKa = 11.84KK3213 pKa = 9.1PRR3215 pKa = 11.84FVYY3218 pKa = 9.63VAKK3221 pKa = 9.89EE3222 pKa = 3.67HH3223 pKa = 6.57TIIQPVLPFDD3233 pKa = 4.23TNRR3236 pKa = 11.84GPPSTATLAYY3246 pKa = 8.81HH3247 pKa = 6.11AHH3249 pKa = 6.5GEE3251 pKa = 4.1ILHH3254 pKa = 6.14EE3255 pKa = 4.08QMKK3258 pKa = 9.77PYY3260 pKa = 10.16KK3261 pKa = 9.18ATEE3264 pKa = 3.85IKK3266 pKa = 9.58TLAGQEE3272 pKa = 4.08QIISEE3277 pKa = 4.6SKK3279 pKa = 7.9WLYY3282 pKa = 9.69YY3283 pKa = 9.89AAKK3286 pKa = 8.61NTRR3289 pKa = 11.84KK3290 pKa = 9.92VDD3292 pKa = 3.11TDD3294 pKa = 3.56YY3295 pKa = 11.82GNKK3298 pKa = 9.85RR3299 pKa = 11.84NGRR3302 pKa = 11.84GIDD3305 pKa = 3.29CRR3307 pKa = 11.84ICYY3310 pKa = 9.5RR3311 pKa = 11.84RR3312 pKa = 11.84GWKK3315 pKa = 9.49AHH3317 pKa = 7.11PDD3319 pKa = 3.35LDD3321 pKa = 3.8ICTCCFSKK3329 pKa = 11.33LEE3331 pKa = 4.18FPQIGNTADD3340 pKa = 3.19EE3341 pKa = 4.39EE3342 pKa = 4.74TIKK3345 pKa = 10.69KK3346 pKa = 8.1YY3347 pKa = 9.49TILKK3351 pKa = 10.0EE3352 pKa = 4.21GGLNRR3357 pKa = 11.84QNQFQAGIGNALSLTTSVPQLSVGLYY3383 pKa = 8.53HH3384 pKa = 6.82GKK3386 pKa = 10.22SYY3388 pKa = 10.82GYY3390 pKa = 7.85STKK3393 pKa = 10.18FNPQGPDD3400 pKa = 3.05GCVKK3404 pKa = 10.49KK3405 pKa = 10.7CIQAYY3410 pKa = 10.31VDD3412 pKa = 4.51LNTEE3416 pKa = 3.69ATRR3419 pKa = 11.84PVMKK3423 pKa = 10.49NNRR3426 pKa = 11.84LTLIQDD3432 pKa = 3.34QPSIIVEE3439 pKa = 4.5EE3440 pKa = 3.99ILKK3443 pKa = 8.16TFNMPSMTPLEE3454 pKa = 4.73HH3455 pKa = 7.06IEE3457 pKa = 4.44PYY3459 pKa = 10.36CHH3461 pKa = 7.62LLGLSTTLVIKK3472 pKa = 10.66GNVRR3476 pKa = 11.84VTVLPDD3482 pKa = 4.5AIGHH3486 pKa = 6.08IEE3488 pKa = 4.15LLIIQTNKK3496 pKa = 10.3LLHH3499 pKa = 6.29CVLVTMNPAYY3509 pKa = 10.81LEE3511 pKa = 3.88TLIRR3515 pKa = 11.84QEE3517 pKa = 4.37TPRR3520 pKa = 11.84LSCTVQNSDD3529 pKa = 5.01SLTTCQICEE3538 pKa = 3.96QQTIDD3543 pKa = 3.17IKK3545 pKa = 10.82AGKK3548 pKa = 8.62GLRR3551 pKa = 11.84VSTQGKK3557 pKa = 8.51CHH3559 pKa = 6.33GLHH3562 pKa = 6.74AEE3564 pKa = 3.69WDD3566 pKa = 4.1RR3567 pKa = 11.84YY3568 pKa = 10.28LVACRR3573 pKa = 11.84RR3574 pKa = 11.84MIMGEE3579 pKa = 4.09MVDD3582 pKa = 3.09RR3583 pKa = 11.84GYY3585 pKa = 10.69WSDD3588 pKa = 2.81KK3589 pKa = 8.49TANHH3593 pKa = 6.0VKK3595 pKa = 10.16SVHH3598 pKa = 5.6QRR3600 pKa = 11.84ITLEE3604 pKa = 4.38KK3605 pKa = 7.74ITHH3608 pKa = 5.69VFRR3611 pKa = 11.84SMTEE3615 pKa = 3.67PVIFSPLSTGNDD3627 pKa = 3.32YY3628 pKa = 11.52IMIEE3632 pKa = 4.19KK3633 pKa = 9.39PQTIKK3638 pKa = 10.57PGQVMIANTEE3648 pKa = 3.68KK3649 pKa = 11.0GIIIGHH3655 pKa = 5.18TLQYY3659 pKa = 9.53KK3660 pKa = 9.83DD3661 pKa = 4.68RR3662 pKa = 11.84MMLVHH3667 pKa = 6.51NMGIVEE3673 pKa = 4.52PLSQAVINLRR3683 pKa = 11.84TTTLPRR3689 pKa = 11.84DD3690 pKa = 4.0YY3691 pKa = 10.91DD3692 pKa = 4.14PKK3694 pKa = 10.93DD3695 pKa = 3.23TDD3697 pKa = 3.04QGKK3700 pKa = 8.99EE3701 pKa = 3.77VTSYY3705 pKa = 11.77NLATRR3710 pKa = 11.84QTMEE3714 pKa = 3.97QIDD3717 pKa = 3.99YY3718 pKa = 10.29NLRR3721 pKa = 11.84YY3722 pKa = 9.91LPISLKK3728 pKa = 9.92GMKK3731 pKa = 10.16VILTDD3736 pKa = 3.48LRR3738 pKa = 11.84NRR3740 pKa = 11.84NHH3742 pKa = 6.59HH3743 pKa = 5.65NEE3745 pKa = 3.62IVAVNIEE3752 pKa = 4.14KK3753 pKa = 10.53ARR3755 pKa = 11.84QFLVDD3760 pKa = 3.44QTMKK3764 pKa = 10.32PLEE3767 pKa = 4.34PEE3769 pKa = 4.14VIEE3772 pKa = 4.1SLKK3775 pKa = 10.59YY3776 pKa = 10.37NGPIVLGLKK3785 pKa = 10.05NGRR3788 pKa = 11.84LEE3790 pKa = 4.14YY3791 pKa = 10.35QHH3793 pKa = 6.65NLVASGPVSGSIIADD3808 pKa = 3.61VEE3810 pKa = 4.12KK3811 pKa = 10.63HH3812 pKa = 4.46LTGLISIKK3820 pKa = 10.16PLEE3823 pKa = 5.14KK3824 pKa = 8.99IDD3826 pKa = 3.7KK3827 pKa = 10.51LKK3829 pKa = 10.21TINPNMFRR3837 pKa = 11.84CLGNEE3842 pKa = 3.78WTFEE3846 pKa = 4.13EE3847 pKa = 5.04YY3848 pKa = 10.28EE3849 pKa = 4.35SEE3851 pKa = 4.25LEE3853 pKa = 4.05KK3854 pKa = 11.13PEE3856 pKa = 3.92MGKK3859 pKa = 10.16DD3860 pKa = 2.9IKK3862 pKa = 11.11DD3863 pKa = 3.15IGEE3866 pKa = 4.13LRR3868 pKa = 11.84DD3869 pKa = 4.78LLMQPGWKK3877 pKa = 8.1TRR3879 pKa = 11.84LRR3881 pKa = 11.84VDD3883 pKa = 3.72QLTPDD3888 pKa = 3.79NFPISLITRR3897 pKa = 11.84GAVIKK3902 pKa = 10.67NAMRR3906 pKa = 11.84VDD3908 pKa = 3.72PGVEE3912 pKa = 3.68VAYY3915 pKa = 10.33RR3916 pKa = 11.84EE3917 pKa = 4.73HH3918 pKa = 7.05ILQVLVCEE3926 pKa = 4.56EE3927 pKa = 4.7DD3928 pKa = 3.5NLLLKK3933 pKa = 10.83DD3934 pKa = 3.81KK3935 pKa = 10.83LLEE3938 pKa = 4.39RR3939 pKa = 11.84DD3940 pKa = 3.19VDD3942 pKa = 4.44FKK3944 pKa = 11.56LQAAQDD3950 pKa = 4.22AIAEE3954 pKa = 4.31EE3955 pKa = 4.15KK3956 pKa = 10.5RR3957 pKa = 11.84RR3958 pKa = 11.84FEE3960 pKa = 3.99SRR3962 pKa = 11.84PFKK3965 pKa = 10.53TIINSEE3971 pKa = 4.18EE3972 pKa = 3.92TFEE3975 pKa = 4.28TVRR3978 pKa = 11.84LLRR3981 pKa = 11.84KK3982 pKa = 9.76RR3983 pKa = 11.84NTVVEE3988 pKa = 4.71TIQYY3992 pKa = 9.87QEE3994 pKa = 4.16YY3995 pKa = 9.93KK3996 pKa = 10.34QGLQAPVQEE4005 pKa = 4.53VDD4007 pKa = 3.12LTQDD4011 pKa = 3.45KK4012 pKa = 10.36RR4013 pKa = 11.84WEE4015 pKa = 4.32DD4016 pKa = 3.81MLSLRR4021 pKa = 11.84PPTNEE4026 pKa = 3.43VYY4028 pKa = 10.98VLTRR4032 pKa = 11.84PEE4034 pKa = 3.85STQMVRR4040 pKa = 11.84RR4041 pKa = 11.84LLEE4044 pKa = 4.33GKK4046 pKa = 7.99VTPQFDD4052 pKa = 3.82TVEE4055 pKa = 4.49GKK4057 pKa = 10.61VKK4059 pKa = 10.21LHH4061 pKa = 5.74VMAPNPTSEE4070 pKa = 5.49FIDD4073 pKa = 4.14LNLDD4077 pKa = 3.77YY4078 pKa = 11.84YY4079 pKa = 10.62MGTHH4083 pKa = 7.39KK4084 pKa = 11.01YY4085 pKa = 9.54QDD4087 pKa = 3.89NIEE4090 pKa = 4.06GLMEE4094 pKa = 4.61SVIQMDD4100 pKa = 4.36DD4101 pKa = 3.29AGQLTSDD4108 pKa = 3.28MHH4110 pKa = 7.88KK4111 pKa = 10.56LVTVPSTLGHH4121 pKa = 5.59VKK4123 pKa = 10.35NLARR4127 pKa = 11.84LTGVPEE4133 pKa = 4.13TPEE4136 pKa = 4.07LAKK4139 pKa = 10.62LAAAILEE4146 pKa = 4.28ANGRR4150 pKa = 11.84KK4151 pKa = 9.8GKK4153 pKa = 6.03TTSHH4157 pKa = 6.2RR4158 pKa = 11.84MVLEE4162 pKa = 4.14DD4163 pKa = 4.07LGEE4166 pKa = 4.28EE4167 pKa = 4.22EE4168 pKa = 5.42LVQLLVPEE4176 pKa = 4.79DD4177 pKa = 3.56PVVIDD4182 pKa = 3.29KK4183 pKa = 10.94SIYY4186 pKa = 9.6SKK4188 pKa = 10.69IGGAVYY4194 pKa = 10.22KK4195 pKa = 9.92PASLVGFGLKK4205 pKa = 10.34DD4206 pKa = 3.6FQKK4209 pKa = 10.77EE4210 pKa = 3.98ALTTRR4215 pKa = 11.84QFWNEE4220 pKa = 3.49NEE4222 pKa = 4.39TKK4224 pKa = 10.47GKK4226 pKa = 10.54YY4227 pKa = 9.99KK4228 pKa = 9.79LTEE4231 pKa = 3.87TMTVEE4236 pKa = 5.51GYY4238 pKa = 11.0NKK4240 pKa = 9.99LHH4242 pKa = 6.41SNKK4245 pKa = 8.33PTIPVNVTSQGQHH4258 pKa = 4.37STSTQTNITTQTTEE4272 pKa = 3.86KK4273 pKa = 10.6EE4274 pKa = 4.04ILEE4277 pKa = 4.37KK4278 pKa = 11.02YY4279 pKa = 7.82ATNEE4283 pKa = 4.35PIVVNQDD4290 pKa = 2.72TVTKK4294 pKa = 9.17YY4295 pKa = 11.0RR4296 pKa = 11.84SMKK4299 pKa = 9.33PNYY4302 pKa = 9.44VEE4304 pKa = 4.33PGCLEE4309 pKa = 3.96TEE4311 pKa = 4.29YY4312 pKa = 11.19VKK4314 pKa = 10.87PRR4316 pKa = 11.84DD4317 pKa = 3.69ITTDD4321 pKa = 3.01AHH4323 pKa = 6.46DD4324 pKa = 4.0SSVKK4328 pKa = 10.3EE4329 pKa = 4.32GEE4331 pKa = 3.88ALGIINTNWMEE4342 pKa = 3.91EE4343 pKa = 4.08DD4344 pKa = 3.83KK4345 pKa = 11.21LLEE4348 pKa = 4.46LLDD4351 pKa = 3.81STTEE4355 pKa = 4.05DD4356 pKa = 3.07KK4357 pKa = 11.32SAGLWVEE4364 pKa = 4.32KK4365 pKa = 10.89VDD4367 pKa = 3.9MDD4369 pKa = 4.03HH4370 pKa = 7.18KK4371 pKa = 11.1LVAEE4375 pKa = 4.51DD4376 pKa = 4.22MNDD4379 pKa = 3.59KK4380 pKa = 11.05INVFTINFFEE4390 pKa = 5.3DD4391 pKa = 3.04NDD4393 pKa = 3.84MTDD4396 pKa = 3.89FNMMVAPTQGVLKK4409 pKa = 10.72SKK4411 pKa = 7.57EE4412 pKa = 4.33TPCRR4416 pKa = 11.84VMEE4419 pKa = 4.16TRR4421 pKa = 11.84KK4422 pKa = 8.56VTLTKK4427 pKa = 10.28RR4428 pKa = 11.84PTGSRR4433 pKa = 11.84PVFNKK4438 pKa = 10.01LANAEE4443 pKa = 4.07FMAVSRR4449 pKa = 11.84RR4450 pKa = 11.84LMSVVTMRR4458 pKa = 11.84KK4459 pKa = 8.62YY4460 pKa = 10.6QLDD4463 pKa = 3.89PKK4465 pKa = 10.21QEE4467 pKa = 3.59WDD4469 pKa = 3.36RR4470 pKa = 11.84FDD4472 pKa = 4.23RR4473 pKa = 11.84NYY4475 pKa = 10.54VSVMGKK4481 pKa = 9.83KK4482 pKa = 10.05LLRR4485 pKa = 11.84AYY4487 pKa = 9.76KK4488 pKa = 10.08EE4489 pKa = 3.73DD4490 pKa = 3.28QIYY4493 pKa = 10.35FNSEE4497 pKa = 4.36EE4498 pKa = 3.68IRR4500 pKa = 11.84KK4501 pKa = 8.74WISSRR4506 pKa = 11.84PDD4508 pKa = 2.93SVKK4511 pKa = 9.63IDD4513 pKa = 3.69RR4514 pKa = 11.84EE4515 pKa = 4.21LEE4517 pKa = 4.1EE4518 pKa = 3.99MLSTGFEE4525 pKa = 3.77INAINTAKK4533 pKa = 10.39VHH4535 pKa = 5.87VKK4537 pKa = 10.64LEE4539 pKa = 4.16SLLKK4543 pKa = 10.23EE4544 pKa = 4.58DD4545 pKa = 4.35YY4546 pKa = 10.61EE4547 pKa = 4.89SVGNRR4552 pKa = 11.84EE4553 pKa = 3.65IEE4555 pKa = 3.77HH4556 pKa = 7.02RR4557 pKa = 11.84IIVWQRR4563 pKa = 11.84KK4564 pKa = 5.77AWCAIFSPVFLQAKK4578 pKa = 9.52ARR4580 pKa = 11.84LKK4582 pKa = 10.75AILSRR4587 pKa = 11.84KK4588 pKa = 8.47VLYY4591 pKa = 10.67ADD4593 pKa = 4.36GLTQEE4598 pKa = 4.58EE4599 pKa = 4.67LSSRR4603 pKa = 11.84VNLIHH4608 pKa = 6.63GDD4610 pKa = 3.53CWFMEE4615 pKa = 5.02DD4616 pKa = 5.63DD4617 pKa = 4.6LSKK4620 pKa = 10.68QDD4622 pKa = 3.38RR4623 pKa = 11.84QTDD4626 pKa = 3.22INLIQCEE4633 pKa = 4.3MYY4635 pKa = 10.0IYY4637 pKa = 10.28SQLGVADD4644 pKa = 4.4DD4645 pKa = 4.52VLNLWRR4651 pKa = 11.84RR4652 pKa = 11.84THH4654 pKa = 6.17EE4655 pKa = 3.65NWKK4658 pKa = 10.17FRR4660 pKa = 11.84GTNVSGILTGMRR4672 pKa = 11.84LTGQATTAVGNAIVNLLVHH4691 pKa = 6.19SRR4693 pKa = 11.84IFEE4696 pKa = 4.23TNKK4699 pKa = 9.87NHH4701 pKa = 6.81IEE4703 pKa = 3.93LMLLLGDD4710 pKa = 4.53DD4711 pKa = 3.95NLVISRR4717 pKa = 11.84NRR4719 pKa = 11.84IDD4721 pKa = 3.64SSKK4724 pKa = 10.43QSKK4727 pKa = 9.59ISKK4730 pKa = 9.75DD4731 pKa = 3.63YY4732 pKa = 11.09YY4733 pKa = 11.31NMVSKK4738 pKa = 10.85ASHH4741 pKa = 7.02DD4742 pKa = 3.77RR4743 pKa = 11.84DD4744 pKa = 3.14QGTFLQLLCYY4754 pKa = 10.28HH4755 pKa = 6.71NPQGVLEE4762 pKa = 4.71FGPDD4766 pKa = 3.91VIRR4769 pKa = 11.84LAQRR4773 pKa = 11.84YY4774 pKa = 7.11EE4775 pKa = 3.91VTNGVSEE4782 pKa = 4.66SNNHH4786 pKa = 4.97NMLARR4791 pKa = 11.84TMSYY4795 pKa = 11.14CMLIGKK4801 pKa = 7.58TMGTKK4806 pKa = 10.3AVVTKK4811 pKa = 10.46HH4812 pKa = 5.82GLPIDD4817 pKa = 4.53LKK4819 pKa = 7.47TTCSMASARR4828 pKa = 11.84RR4829 pKa = 11.84ACAIKK4834 pKa = 10.44RR4835 pKa = 11.84KK4836 pKa = 6.98MTLGEE4841 pKa = 4.07VEE4843 pKa = 4.51SYY4845 pKa = 10.85EE4846 pKa = 4.3SYY4848 pKa = 10.64LYY4850 pKa = 11.42RR4851 pKa = 11.84MMKK4854 pKa = 10.06DD4855 pKa = 3.37LKK4857 pKa = 8.15THH4859 pKa = 4.84TWIFKK4864 pKa = 10.28HH4865 pKa = 6.04LAA4867 pKa = 3.35

Molecular weight: 551.66 kDa
Isoelectric point according different methods:

Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try ESI

ChTry ESI

ArgC ESI

LysN ESI

TryLysC ESI

Try MALDI

ChTry MALDI

ArgC MALDI

LysN MALDI

TryLysC MALDI

Try LTQ

ChTry LTQ

ArgC LTQ

LysN LTQ

TryLysC LTQ

Try MSlow

ChTry MSlow

ArgC MSlow

LysN MSlow

TryLysC MSlow

Try MShigh

ChTry MShigh

ArgC MShigh

LysN MShigh

TryLysC MShigh

General Statistics

Number of major isoforms	Number of additional isoforms	Number of all proteins	Number of amino acids	Min. Seq. Length	Max. Seq. Length	Avg. Seq. Length	Avg. Mol. Weight
1	0	1	4867	4867	4867	4867.0	551.66

Amino acid frequency

Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu
5.013 ± 0.0	1.89 ± 0.0	5.65 ± 0.0	6.904 ± 0.0	2.404 ± 0.0	5.527 ± 0.0	2.835 ± 0.0	6.801 ± 0.0	7.725 ± 0.0	9.534 ± 0.0

Met	Asn	Gln	Pro	Arg	Ser	Thr	Val	Trp	Tyr
3.246 ± 0.0	4.582 ± 0.0	4.171 ± 0.0	4.048 ± 0.0	5.075 ± 0.0	5.815 ± 0.0	7.705 ± 0.0	6.821 ± 0.0	1.048 ± 0.0	3.205 ± 0.0

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here

See this proteome in:

Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski