Amino acid dipepetide frequency for Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.296AlaAla: 8.296 ± 0.047	1.121AlaCys: 1.121 ± 0.013	4.091AlaAsp: 4.091 ± 0.023	4.987AlaGlu: 4.987 ± 0.035	3.092AlaPhe: 3.092 ± 0.02	5.434AlaGly: 5.434 ± 0.029	1.683AlaHis: 1.683 ± 0.015	4.421AlaIle: 4.421 ± 0.026	4.094AlaLys: 4.094 ± 0.027	7.488AlaLeu: 7.488 ± 0.038	1.982AlaMet: 1.982 ± 0.017	2.934AlaAsn: 2.934 ± 0.02	4.652AlaPro: 4.652 ± 0.033	3.329AlaGln: 3.329 ± 0.022	4.544AlaArg: 4.544 ± 0.028	7.061AlaSer: 7.061 ± 0.038	5.199AlaThr: 5.199 ± 0.029	5.117AlaVal: 5.117 ± 0.029	1.177AlaTrp: 1.177 ± 0.012	2.12AlaTyr: 2.12 ± 0.016	0.0AlaXaa: 0.0 ± 0.0
Cys	0.95CysAla: 0.95 ± 0.012	0.284CysCys: 0.284 ± 0.007	0.753CysAsp: 0.753 ± 0.011	0.647CysGlu: 0.647 ± 0.009	0.584CysPhe: 0.584 ± 0.009	0.953CysGly: 0.953 ± 0.013	0.365CysHis: 0.365 ± 0.007	0.786CysIle: 0.786 ± 0.011	0.589CysLys: 0.589 ± 0.01	1.34CysLeu: 1.34 ± 0.015	0.289CysMet: 0.289 ± 0.006	0.48CysAsn: 0.48 ± 0.008	0.695CysPro: 0.695 ± 0.012	0.526CysGln: 0.526 ± 0.009	0.816CysArg: 0.816 ± 0.011	0.987CysSer: 0.987 ± 0.013	0.745CysThr: 0.745 ± 0.011	0.842CysVal: 0.842 ± 0.014	0.226CysTrp: 0.226 ± 0.006	0.401CysTyr: 0.401 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.597AspAla: 4.597 ± 0.024	0.691AspCys: 0.691 ± 0.011	4.416AspAsp: 4.416 ± 0.036	4.568AspGlu: 4.568 ± 0.033	2.283AspPhe: 2.283 ± 0.016	4.033AspGly: 4.033 ± 0.028	1.306AspHis: 1.306 ± 0.015	3.261AspIle: 3.261 ± 0.022	2.718AspLys: 2.718 ± 0.022	5.139AspLeu: 5.139 ± 0.03	1.388AspMet: 1.388 ± 0.013	2.038AspAsn: 2.038 ± 0.017	3.306AspPro: 3.306 ± 0.023	1.96AspGln: 1.96 ± 0.015	3.013AspArg: 3.013 ± 0.024	4.166AspSer: 4.166 ± 0.027	3.104AspThr: 3.104 ± 0.022	3.654AspVal: 3.654 ± 0.023	0.927AspTrp: 0.927 ± 0.011	1.636AspTyr: 1.636 ± 0.015	0.0AspXaa: 0.0 ± 0.0
Glu	5.465GluAla: 5.465 ± 0.036	0.679GluCys: 0.679 ± 0.01	4.217GluAsp: 4.217 ± 0.034	5.251GluGlu: 5.251 ± 0.048	2.004GluPhe: 2.004 ± 0.015	3.606GluGly: 3.606 ± 0.024	1.432GluHis: 1.432 ± 0.014	3.095GluIle: 3.095 ± 0.018	3.728GluLys: 3.728 ± 0.029	5.195GluLeu: 5.195 ± 0.029	1.491GluMet: 1.491 ± 0.013	2.362GluAsn: 2.362 ± 0.017	2.956GluPro: 2.956 ± 0.026	2.425GluGln: 2.425 ± 0.021	3.731GluArg: 3.731 ± 0.029	4.375GluSer: 4.375 ± 0.027	3.755GluThr: 3.755 ± 0.025	3.575GluVal: 3.575 ± 0.023	0.905GluTrp: 0.905 ± 0.011	1.674GluTyr: 1.674 ± 0.016	0.0GluXaa: 0.0 ± 0.0
Phe	2.959PheAla: 2.959 ± 0.019	0.602PheCys: 0.602 ± 0.01	2.388PheAsp: 2.388 ± 0.02	2.211PheGlu: 2.211 ± 0.017	1.666PhePhe: 1.666 ± 0.019	2.871PheGly: 2.871 ± 0.025	0.92PheHis: 0.92 ± 0.012	1.961PheIle: 1.961 ± 0.015	1.662PheLys: 1.662 ± 0.014	3.466PheLeu: 3.466 ± 0.026	0.843PheMet: 0.843 ± 0.011	1.514PheAsn: 1.514 ± 0.015	1.919PhePro: 1.919 ± 0.014	1.428PheGln: 1.428 ± 0.011	1.931PheArg: 1.931 ± 0.018	3.037PheSer: 3.037 ± 0.022	2.231PheThr: 2.231 ± 0.018	2.372PheVal: 2.372 ± 0.019	0.673PheTrp: 0.673 ± 0.01	1.129PheTyr: 1.129 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	4.984GlyAla: 4.984 ± 0.034	0.925GlyCys: 0.925 ± 0.011	3.686GlyAsp: 3.686 ± 0.027	3.482GlyGlu: 3.482 ± 0.024	2.817GlyPhe: 2.817 ± 0.021	5.364GlyGly: 5.364 ± 0.042	1.711GlyHis: 1.711 ± 0.018	3.621GlyIle: 3.621 ± 0.022	3.407GlyLys: 3.407 ± 0.025	6.018GlyLeu: 6.018 ± 0.034	1.578GlyMet: 1.578 ± 0.015	2.657GlyAsn: 2.657 ± 0.018	3.31GlyPro: 3.31 ± 0.024	2.607GlyGln: 2.607 ± 0.02	3.939GlyArg: 3.939 ± 0.026	5.758GlySer: 5.758 ± 0.034	3.98GlyThr: 3.98 ± 0.033	4.119GlyVal: 4.119 ± 0.021	1.171GlyTrp: 1.171 ± 0.013	2.193GlyTyr: 2.193 ± 0.018	0.0GlyXaa: 0.0 ± 0.0
His	1.747HisAla: 1.747 ± 0.016	0.354HisCys: 0.354 ± 0.007	1.385HisAsp: 1.385 ± 0.014	1.392HisGlu: 1.392 ± 0.013	0.938HisPhe: 0.938 ± 0.012	1.747HisGly: 1.747 ± 0.018	0.872HisHis: 0.872 ± 0.016	1.266HisIle: 1.266 ± 0.013	0.998HisLys: 0.998 ± 0.012	2.26HisLeu: 2.26 ± 0.018	0.547HisMet: 0.547 ± 0.009	0.877HisAsn: 0.877 ± 0.01	1.551HisPro: 1.551 ± 0.016	1.045HisGln: 1.045 ± 0.012	1.529HisArg: 1.529 ± 0.015	1.81HisSer: 1.81 ± 0.019	1.209HisThr: 1.209 ± 0.014	1.42HisVal: 1.42 ± 0.013	0.365HisTrp: 0.365 ± 0.007	0.724HisTyr: 0.724 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.264IleAla: 4.264 ± 0.023	0.817IleCys: 0.817 ± 0.012	3.028IleAsp: 3.028 ± 0.017	3.032IleGlu: 3.032 ± 0.023	2.074IlePhe: 2.074 ± 0.018	3.29IleGly: 3.29 ± 0.025	1.257IleHis: 1.257 ± 0.013	2.701IleIle: 2.701 ± 0.025	2.401IleLys: 2.401 ± 0.017	4.673IleLeu: 4.673 ± 0.028	1.125IleMet: 1.125 ± 0.013	1.962IleAsn: 1.962 ± 0.016	3.086IlePro: 3.086 ± 0.02	1.965IleGln: 1.965 ± 0.018	2.827IleArg: 2.827 ± 0.019	4.014IleSer: 4.014 ± 0.028	2.966IleThr: 2.966 ± 0.025	3.227IleVal: 3.227 ± 0.023	0.791IleTrp: 0.791 ± 0.01	1.458IleTyr: 1.458 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.373LysAla: 4.373 ± 0.032	0.592LysCys: 0.592 ± 0.009	3.088LysAsp: 3.088 ± 0.023	3.438LysGlu: 3.438 ± 0.028	1.555LysPhe: 1.555 ± 0.014	3.073LysGly: 3.073 ± 0.022	1.203LysHis: 1.203 ± 0.015	2.363LysIle: 2.363 ± 0.02	3.411LysLys: 3.411 ± 0.036	4.249LysLeu: 4.249 ± 0.025	1.058LysMet: 1.058 ± 0.011	1.904LysAsn: 1.904 ± 0.018	2.919LysPro: 2.919 ± 0.023	1.893LysGln: 1.893 ± 0.017	3.36LysArg: 3.36 ± 0.023	3.633LysSer: 3.633 ± 0.023	3.059LysThr: 3.059 ± 0.022	2.894LysVal: 2.894 ± 0.021	0.732LysTrp: 0.732 ± 0.01	1.431LysTyr: 1.431 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	7.532LeuAla: 7.532 ± 0.034	1.277LeuCys: 1.277 ± 0.014	5.188LeuAsp: 5.188 ± 0.032	5.592LeuGlu: 5.592 ± 0.033	3.368LeuPhe: 3.368 ± 0.025	5.876LeuGly: 5.876 ± 0.027	2.173LeuHis: 2.173 ± 0.019	4.186LeuIle: 4.186 ± 0.025	4.351LeuLys: 4.351 ± 0.027	8.092LeuLeu: 8.092 ± 0.046	1.872LeuMet: 1.872 ± 0.018	3.213LeuAsn: 3.213 ± 0.021	5.248LeuPro: 5.248 ± 0.029	3.773LeuGln: 3.773 ± 0.029	5.493LeuArg: 5.493 ± 0.028	7.263LeuSer: 7.263 ± 0.032	4.826LeuThr: 4.826 ± 0.027	5.343LeuVal: 5.343 ± 0.028	1.237LeuTrp: 1.237 ± 0.013	2.361LeuTyr: 2.361 ± 0.019	0.0LeuXaa: 0.0 ± 0.0
Met	2.278MetAla: 2.278 ± 0.019	0.272MetCys: 0.272 ± 0.006	1.295MetAsp: 1.295 ± 0.013	1.296MetGlu: 1.296 ± 0.013	0.795MetPhe: 0.795 ± 0.011	1.492MetGly: 1.492 ± 0.015	0.502MetHis: 0.502 ± 0.008	1.093MetIle: 1.093 ± 0.012	1.093MetLys: 1.093 ± 0.012	1.899MetLeu: 1.899 ± 0.016	0.644MetMet: 0.644 ± 0.01	0.87MetAsn: 0.87 ± 0.011	1.344MetPro: 1.344 ± 0.012	0.87MetGln: 0.87 ± 0.011	1.263MetArg: 1.263 ± 0.013	2.048MetSer: 2.048 ± 0.016	1.395MetThr: 1.395 ± 0.012	1.328MetVal: 1.328 ± 0.012	0.275MetTrp: 0.275 ± 0.006	0.558MetTyr: 0.558 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.087AsnAla: 3.087 ± 0.021	0.493AsnCys: 0.493 ± 0.008	2.094AsnAsp: 2.094 ± 0.016	2.126AsnGlu: 2.126 ± 0.016	1.424AsnPhe: 1.424 ± 0.012	3.03AsnGly: 3.03 ± 0.022	0.88AsnHis: 0.88 ± 0.012	2.129AsnIle: 2.129 ± 0.018	1.766AsnLys: 1.766 ± 0.015	3.334AsnLeu: 3.334 ± 0.024	0.942AsnMet: 0.942 ± 0.013	1.617AsnAsn: 1.617 ± 0.018	2.428AsnPro: 2.428 ± 0.017	1.43AsnGln: 1.43 ± 0.014	1.955AsnArg: 1.955 ± 0.016	2.902AsnSer: 2.902 ± 0.022	2.271AsnThr: 2.271 ± 0.019	2.256AsnVal: 2.256 ± 0.019	0.617AsnTrp: 0.617 ± 0.009	1.095AsnTyr: 1.095 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.873ProAla: 4.873 ± 0.03	0.584ProCys: 0.584 ± 0.01	3.275ProAsp: 3.275 ± 0.023	3.959ProGlu: 3.959 ± 0.025	2.078ProPhe: 2.078 ± 0.019	3.965ProGly: 3.965 ± 0.032	1.278ProHis: 1.278 ± 0.014	2.566ProIle: 2.566 ± 0.017	2.803ProLys: 2.803 ± 0.02	4.55ProLeu: 4.55 ± 0.026	1.145ProMet: 1.145 ± 0.013	2.218ProAsn: 2.218 ± 0.019	4.748ProPro: 4.748 ± 0.055	2.566ProGln: 2.566 ± 0.026	3.337ProArg: 3.337 ± 0.025	5.756ProSer: 5.756 ± 0.038	3.859ProThr: 3.859 ± 0.028	3.587ProVal: 3.587 ± 0.024	0.786ProTrp: 0.786 ± 0.01	1.542ProTyr: 1.542 ± 0.015	0.0ProXaa: 0.0 ± 0.0
Gln	3.472GlnAla: 3.472 ± 0.023	0.465GlnCys: 0.465 ± 0.008	2.28GlnAsp: 2.28 ± 0.017	2.474GlnGlu: 2.474 ± 0.021	1.291GlnPhe: 1.291 ± 0.012	2.537GlnGly: 2.537 ± 0.019	1.096GlnHis: 1.096 ± 0.014	1.879GlnIle: 1.879 ± 0.015	2.009GlnLys: 2.009 ± 0.018	3.423GlnLeu: 3.423 ± 0.025	0.929GlnMet: 0.929 ± 0.015	1.586GlnAsn: 1.586 ± 0.012	2.618GlnPro: 2.618 ± 0.023	2.451GlnGln: 2.451 ± 0.038	2.563GlnArg: 2.563 ± 0.023	3.096GlnSer: 3.096 ± 0.02	2.33GlnThr: 2.33 ± 0.016	2.242GlnVal: 2.242 ± 0.016	0.6GlnTrp: 0.6 ± 0.009	1.153GlnTyr: 1.153 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.312ArgAla: 4.312 ± 0.027	0.765ArgCys: 0.765 ± 0.011	3.429ArgAsp: 3.429 ± 0.03	3.636ArgGlu: 3.636 ± 0.026	2.139ArgPhe: 2.139 ± 0.018	3.574ArgGly: 3.574 ± 0.025	1.582ArgHis: 1.582 ± 0.016	2.89ArgIle: 2.89 ± 0.018	3.328ArgLys: 3.328 ± 0.024	5.325ArgLeu: 5.325 ± 0.031	1.326ArgMet: 1.326 ± 0.014	2.272ArgAsn: 2.272 ± 0.017	3.449ArgPro: 3.449 ± 0.026	2.55ArgGln: 2.55 ± 0.022	4.846ArgArg: 4.846 ± 0.033	4.672ArgSer: 4.672 ± 0.032	3.103ArgThr: 3.103 ± 0.025	3.258ArgVal: 3.258 ± 0.021	0.917ArgTrp: 0.917 ± 0.011	1.694ArgTyr: 1.694 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	6.259SerAla: 6.259 ± 0.04	0.987SerCys: 0.987 ± 0.013	4.385SerAsp: 4.385 ± 0.031	4.249SerGlu: 4.249 ± 0.025	3.148SerPhe: 3.148 ± 0.022	5.467SerGly: 5.467 ± 0.038	2.0SerHis: 2.0 ± 0.018	4.187SerIle: 4.187 ± 0.023	3.885SerLys: 3.885 ± 0.024	7.201SerLeu: 7.201 ± 0.037	1.826SerMet: 1.826 ± 0.017	3.105SerAsn: 3.105 ± 0.023	5.333SerPro: 5.333 ± 0.036	3.387SerGln: 3.387 ± 0.024	4.97SerArg: 4.97 ± 0.03	8.433SerSer: 8.433 ± 0.061	5.433SerThr: 5.433 ± 0.042	4.575SerVal: 4.575 ± 0.029	1.194SerTrp: 1.194 ± 0.012	2.151SerTyr: 2.151 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.088ThrAla: 5.088 ± 0.024	0.811ThrCys: 0.811 ± 0.011	2.917ThrAsp: 2.917 ± 0.021	3.343ThrGlu: 3.343 ± 0.026	2.266ThrPhe: 2.266 ± 0.016	4.108ThrGly: 4.108 ± 0.035	1.262ThrHis: 1.262 ± 0.011	3.232ThrIle: 3.232 ± 0.031	2.884ThrLys: 2.884 ± 0.021	5.137ThrLeu: 5.137 ± 0.026	1.245ThrMet: 1.245 ± 0.012	2.23ThrAsn: 2.23 ± 0.016	4.199ThrPro: 4.199 ± 0.031	2.199ThrGln: 2.199 ± 0.018	3.132ThrArg: 3.132 ± 0.023	5.346ThrSer: 5.346 ± 0.045	4.371ThrThr: 4.371 ± 0.058	3.721ThrVal: 3.721 ± 0.034	0.901ThrTrp: 0.901 ± 0.01	1.64ThrTyr: 1.64 ± 0.015	0.0ThrXaa: 0.0 ± 0.0
Val	5.027ValAla: 5.027 ± 0.031	0.868ValCys: 0.868 ± 0.011	3.663ValAsp: 3.663 ± 0.022	3.801ValGlu: 3.801 ± 0.024	2.459ValPhe: 2.459 ± 0.022	3.817ValGly: 3.817 ± 0.022	1.352ValHis: 1.352 ± 0.012	3.066ValIle: 3.066 ± 0.023	3.027ValLys: 3.027 ± 0.021	5.409ValLeu: 5.409 ± 0.029	1.35ValMet: 1.35 ± 0.013	2.246ValAsn: 2.246 ± 0.02	3.557ValPro: 3.557 ± 0.027	2.35ValGln: 2.35 ± 0.018	3.225ValArg: 3.225 ± 0.019	4.646ValSer: 4.646 ± 0.027	3.619ValThr: 3.619 ± 0.032	4.126ValVal: 4.126 ± 0.03	0.878ValTrp: 0.878 ± 0.012	1.741ValTyr: 1.741 ± 0.015	0.0ValXaa: 0.0 ± 0.0
Trp	1.173TrpAla: 1.173 ± 0.013	0.216TrpCys: 0.216 ± 0.005	0.93TrpAsp: 0.93 ± 0.011	0.853TrpGlu: 0.853 ± 0.009	0.585TrpPhe: 0.585 ± 0.009	0.973TrpGly: 0.973 ± 0.012	0.383TrpHis: 0.383 ± 0.008	0.821TrpIle: 0.821 ± 0.012	0.855TrpLys: 0.855 ± 0.012	1.428TrpLeu: 1.428 ± 0.015	0.388TrpMet: 0.388 ± 0.006	0.641TrpAsn: 0.641 ± 0.01	0.658TrpPro: 0.658 ± 0.01	0.601TrpGln: 0.601 ± 0.009	0.918TrpArg: 0.918 ± 0.01	1.108TrpSer: 1.108 ± 0.012	0.951TrpThr: 0.951 ± 0.012	0.916TrpVal: 0.916 ± 0.012	0.293TrpTrp: 0.293 ± 0.006	0.453TrpTyr: 0.453 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.087TyrAla: 2.087 ± 0.018	0.456TyrCys: 0.456 ± 0.008	1.696TyrAsp: 1.696 ± 0.015	1.583TyrGlu: 1.583 ± 0.014	1.213TyrPhe: 1.213 ± 0.013	2.116TyrGly: 2.116 ± 0.017	0.781TyrHis: 0.781 ± 0.009	1.438TyrIle: 1.438 ± 0.015	1.218TyrLys: 1.218 ± 0.015	2.638TyrLeu: 2.638 ± 0.019	0.641TyrMet: 0.641 ± 0.009	1.149TyrAsn: 1.149 ± 0.012	1.498TyrPro: 1.498 ± 0.017	1.139TyrGln: 1.139 ± 0.013	1.673TyrArg: 1.673 ± 0.013	2.066TyrSer: 2.066 ± 0.017	1.628TyrThr: 1.628 ± 0.017	1.656TyrVal: 1.656 ± 0.014	0.479TyrTrp: 0.479 ± 0.008	0.94TyrTyr: 0.94 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 17877 proteins (8236446 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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