Amino acid dipepetide frequency for Canine adenovirus serotype 2 (CAdV-2) (Canine adenovirus 2)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.447AlaAla: 6.447 ± 1.519
0.848AlaCys: 0.848 ± 0.384
3.054AlaAsp: 3.054 ± 0.684
4.072AlaGlu: 4.072 ± 1.006
3.393AlaPhe: 3.393 ± 0.616
3.902AlaGly: 3.902 ± 0.836
2.884AlaHis: 2.884 ± 0.571
3.054AlaIle: 3.054 ± 0.573
2.206AlaLys: 2.206 ± 0.704
8.483AlaLeu: 8.483 ± 0.814
2.884AlaMet: 2.884 ± 0.791
4.751AlaAsn: 4.751 ± 1.205
5.26AlaPro: 5.26 ± 0.998
3.054AlaGln: 3.054 ± 0.582
5.26AlaArg: 5.26 ± 1.292
5.429AlaSer: 5.429 ± 1.078
4.242AlaThr: 4.242 ± 0.623
5.938AlaVal: 5.938 ± 0.601
0.679AlaTrp: 0.679 ± 0.382
2.884AlaTyr: 2.884 ± 0.511
0.0AlaXaa: 0.0 ± 0.0
Cys
1.527CysAla: 1.527 ± 0.453
0.509CysCys: 0.509 ± 0.387
0.509CysAsp: 0.509 ± 0.221
0.509CysGlu: 0.509 ± 0.257
0.679CysPhe: 0.679 ± 0.365
0.848CysGly: 0.848 ± 0.447
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.509CysLys: 0.509 ± 0.366
1.866CysLeu: 1.866 ± 0.525
0.17CysMet: 0.17 ± 0.181
1.018CysAsn: 1.018 ± 0.409
0.679CysPro: 0.679 ± 0.386
0.509CysGln: 0.509 ± 0.227
1.188CysArg: 1.188 ± 0.417
0.848CysSer: 0.848 ± 0.382
0.848CysThr: 0.848 ± 0.323
1.188CysVal: 1.188 ± 0.595
0.0CysTrp: 0.0 ± 0.0
0.848CysTyr: 0.848 ± 0.309
0.0CysXaa: 0.0 ± 0.0
Asp
2.715AspAla: 2.715 ± 0.902
0.848AspCys: 0.848 ± 0.359
2.036AspAsp: 2.036 ± 0.96
2.375AspGlu: 2.375 ± 0.96
2.545AspPhe: 2.545 ± 0.687
2.375AspGly: 2.375 ± 0.557
1.357AspHis: 1.357 ± 0.46
3.054AspIle: 3.054 ± 0.928
1.357AspLys: 1.357 ± 0.527
3.902AspLeu: 3.902 ± 0.726
0.848AspMet: 0.848 ± 0.538
1.866AspAsn: 1.866 ± 0.588
2.715AspPro: 2.715 ± 0.662
1.357AspGln: 1.357 ± 0.417
2.375AspArg: 2.375 ± 0.855
2.715AspSer: 2.715 ± 0.894
3.224AspThr: 3.224 ± 0.508
3.902AspVal: 3.902 ± 1.034
0.17AspTrp: 0.17 ± 0.153
1.866AspTyr: 1.866 ± 0.608
0.0AspXaa: 0.0 ± 0.0
Glu
5.429GluAla: 5.429 ± 1.181
0.848GluCys: 0.848 ± 0.418
4.242GluAsp: 4.242 ± 0.93
6.278GluGlu: 6.278 ± 1.448
1.697GluPhe: 1.697 ± 0.48
5.429GluGly: 5.429 ± 0.65
1.018GluHis: 1.018 ± 0.38
1.866GluIle: 1.866 ± 0.646
1.527GluLys: 1.527 ± 0.384
5.938GluLeu: 5.938 ± 1.211
1.697GluMet: 1.697 ± 0.74
4.581GluAsn: 4.581 ± 0.739
3.733GluPro: 3.733 ± 0.748
1.188GluGln: 1.188 ± 0.517
4.072GluArg: 4.072 ± 1.113
4.242GluSer: 4.242 ± 0.827
2.884GluThr: 2.884 ± 1.172
5.599GluVal: 5.599 ± 0.928
0.679GluTrp: 0.679 ± 0.275
0.848GluTyr: 0.848 ± 0.333
0.0GluXaa: 0.0 ± 0.0
Phe
2.036PheAla: 2.036 ± 0.494
1.357PheCys: 1.357 ± 0.661
1.866PheAsp: 1.866 ± 0.533
2.715PheGlu: 2.715 ± 0.653
2.545PhePhe: 2.545 ± 0.495
0.848PheGly: 0.848 ± 0.355
1.018PheHis: 1.018 ± 0.322
1.697PheIle: 1.697 ± 0.427
3.224PheLys: 3.224 ± 0.941
4.581PheLeu: 4.581 ± 0.83
1.527PheMet: 1.527 ± 0.273
2.375PheAsn: 2.375 ± 0.545
1.188PhePro: 1.188 ± 0.264
1.527PheGln: 1.527 ± 0.408
2.375PheArg: 2.375 ± 0.739
3.054PheSer: 3.054 ± 0.496
2.545PheThr: 2.545 ± 0.65
2.884PheVal: 2.884 ± 0.372
0.17PheTrp: 0.17 ± 0.165
2.545PheTyr: 2.545 ± 0.395
0.0PheXaa: 0.0 ± 0.0
Gly
5.769GlyAla: 5.769 ± 0.73
0.679GlyCys: 0.679 ± 0.422
3.054GlyAsp: 3.054 ± 0.623
3.224GlyGlu: 3.224 ± 1.073
2.545GlyPhe: 2.545 ± 0.746
3.563GlyGly: 3.563 ± 0.934
0.848GlyHis: 0.848 ± 0.369
2.715GlyIle: 2.715 ± 0.973
1.188GlyLys: 1.188 ± 0.448
5.599GlyLeu: 5.599 ± 0.904
1.866GlyMet: 1.866 ± 0.645
2.715GlyAsn: 2.715 ± 0.8
3.054GlyPro: 3.054 ± 0.731
3.393GlyGln: 3.393 ± 1.147
3.902GlyArg: 3.902 ± 0.831
3.563GlySer: 3.563 ± 0.675
3.224GlyThr: 3.224 ± 0.609
3.733GlyVal: 3.733 ± 0.817
0.848GlyTrp: 0.848 ± 0.375
1.527GlyTyr: 1.527 ± 0.724
0.0GlyXaa: 0.0 ± 0.0
His
1.018HisAla: 1.018 ± 0.704
0.17HisCys: 0.17 ± 0.145
0.679HisAsp: 0.679 ± 0.267
1.527HisGlu: 1.527 ± 0.592
1.188HisPhe: 1.188 ± 0.637
1.527HisGly: 1.527 ± 0.497
0.848HisHis: 0.848 ± 0.386
0.848HisIle: 0.848 ± 0.332
1.527HisLys: 1.527 ± 0.51
3.224HisLeu: 3.224 ± 0.516
0.509HisMet: 0.509 ± 0.291
1.018HisAsn: 1.018 ± 0.41
1.866HisPro: 1.866 ± 0.709
0.679HisGln: 0.679 ± 0.452
2.206HisArg: 2.206 ± 0.475
1.018HisSer: 1.018 ± 0.47
1.188HisThr: 1.188 ± 0.419
0.848HisVal: 0.848 ± 0.39
0.17HisTrp: 0.17 ± 0.169
1.527HisTyr: 1.527 ± 0.354
0.0HisXaa: 0.0 ± 0.0
Ile
2.206IleAla: 2.206 ± 0.619
0.17IleCys: 0.17 ± 0.143
1.697IleAsp: 1.697 ± 0.445
1.357IleGlu: 1.357 ± 0.357
1.527IlePhe: 1.527 ± 0.468
2.375IleGly: 2.375 ± 0.852
1.018IleHis: 1.018 ± 0.533
1.188IleIle: 1.188 ± 0.416
3.054IleLys: 3.054 ± 0.72
3.393IleLeu: 3.393 ± 0.732
0.848IleMet: 0.848 ± 0.389
2.715IleAsn: 2.715 ± 0.733
2.884IlePro: 2.884 ± 0.761
2.036IleGln: 2.036 ± 0.678
3.054IleArg: 3.054 ± 0.804
3.902IleSer: 3.902 ± 0.82
3.563IleThr: 3.563 ± 0.929
3.054IleVal: 3.054 ± 0.597
0.509IleTrp: 0.509 ± 0.291
0.848IleTyr: 0.848 ± 0.356
0.0IleXaa: 0.0 ± 0.0
Lys
3.393LysAla: 3.393 ± 1.301
0.509LysCys: 0.509 ± 0.438
1.866LysAsp: 1.866 ± 0.423
2.884LysGlu: 2.884 ± 0.935
2.036LysPhe: 2.036 ± 0.517
1.697LysGly: 1.697 ± 0.674
0.509LysHis: 0.509 ± 0.292
2.715LysIle: 2.715 ± 0.763
2.036LysLys: 2.036 ± 0.847
3.902LysLeu: 3.902 ± 1.0
0.848LysMet: 0.848 ± 0.594
1.697LysAsn: 1.697 ± 0.476
2.375LysPro: 2.375 ± 0.641
1.527LysGln: 1.527 ± 0.4
3.733LysArg: 3.733 ± 1.249
2.715LysSer: 2.715 ± 0.744
2.715LysThr: 2.715 ± 0.772
3.224LysVal: 3.224 ± 0.772
0.509LysTrp: 0.509 ± 0.275
1.357LysTyr: 1.357 ± 0.364
0.0LysXaa: 0.0 ± 0.0
Leu
8.483LeuAla: 8.483 ± 1.273
1.018LeuCys: 1.018 ± 0.518
3.902LeuAsp: 3.902 ± 0.644
5.769LeuGlu: 5.769 ± 1.184
3.054LeuPhe: 3.054 ± 0.613
6.447LeuGly: 6.447 ± 1.02
2.715LeuHis: 2.715 ± 0.712
3.393LeuIle: 3.393 ± 0.639
4.92LeuLys: 4.92 ± 1.062
10.519LeuLeu: 10.519 ± 1.004
2.545LeuMet: 2.545 ± 0.528
4.242LeuAsn: 4.242 ± 0.724
7.974LeuPro: 7.974 ± 0.989
3.902LeuGln: 3.902 ± 0.755
4.92LeuArg: 4.92 ± 1.255
7.126LeuSer: 7.126 ± 1.061
4.92LeuThr: 4.92 ± 1.163
6.278LeuVal: 6.278 ± 0.968
0.848LeuTrp: 0.848 ± 0.241
2.036LeuTyr: 2.036 ± 0.944
0.0LeuXaa: 0.0 ± 0.0
Met
4.072MetAla: 4.072 ± 0.751
0.848MetCys: 0.848 ± 0.363
1.357MetAsp: 1.357 ± 0.498
2.545MetGlu: 2.545 ± 0.706
0.848MetPhe: 0.848 ± 0.336
2.036MetGly: 2.036 ± 0.648
0.679MetHis: 0.679 ± 0.448
0.679MetIle: 0.679 ± 0.272
0.848MetLys: 0.848 ± 0.331
3.224MetLeu: 3.224 ± 0.832
0.679MetMet: 0.679 ± 0.291
1.018MetAsn: 1.018 ± 0.304
2.036MetPro: 2.036 ± 0.655
1.188MetGln: 1.188 ± 0.458
1.527MetArg: 1.527 ± 0.603
2.036MetSer: 2.036 ± 0.645
1.018MetThr: 1.018 ± 0.477
0.679MetVal: 0.679 ± 0.23
0.509MetTrp: 0.509 ± 0.363
1.018MetTyr: 1.018 ± 0.346
0.0MetXaa: 0.0 ± 0.0
Asn
3.902AsnAla: 3.902 ± 0.71
0.509AsnCys: 0.509 ± 0.221
2.545AsnAsp: 2.545 ± 0.546
2.884AsnGlu: 2.884 ± 0.619
3.733AsnPhe: 3.733 ± 0.655
3.054AsnGly: 3.054 ± 0.694
0.848AsnHis: 0.848 ± 0.359
3.393AsnIle: 3.393 ± 0.772
1.357AsnLys: 1.357 ± 0.4
4.92AsnLeu: 4.92 ± 1.236
1.527AsnMet: 1.527 ± 0.522
3.733AsnAsn: 3.733 ± 0.989
3.733AsnPro: 3.733 ± 0.632
1.188AsnGln: 1.188 ± 0.422
2.036AsnArg: 2.036 ± 0.555
3.224AsnSer: 3.224 ± 0.531
2.545AsnThr: 2.545 ± 0.924
4.242AsnVal: 4.242 ± 0.766
1.188AsnTrp: 1.188 ± 0.389
2.715AsnTyr: 2.715 ± 0.937
0.0AsnXaa: 0.0 ± 0.0
Pro
5.938ProAla: 5.938 ± 1.005
1.188ProCys: 1.188 ± 0.471
2.715ProAsp: 2.715 ± 0.579
5.26ProGlu: 5.26 ± 0.61
1.527ProPhe: 1.527 ± 0.662
2.715ProGly: 2.715 ± 0.877
1.357ProHis: 1.357 ± 0.414
2.206ProIle: 2.206 ± 0.682
2.884ProLys: 2.884 ± 0.88
4.751ProLeu: 4.751 ± 1.018
1.697ProMet: 1.697 ± 0.416
3.054ProAsn: 3.054 ± 0.616
6.278ProPro: 6.278 ± 1.882
1.697ProGln: 1.697 ± 0.502
5.09ProArg: 5.09 ± 0.868
5.599ProSer: 5.599 ± 1.191
3.902ProThr: 3.902 ± 0.864
4.072ProVal: 4.072 ± 0.696
0.0ProTrp: 0.0 ± 0.0
2.375ProTyr: 2.375 ± 0.883
0.0ProXaa: 0.0 ± 0.0
Gln
4.242GlnAla: 4.242 ± 0.919
0.509GlnCys: 0.509 ± 0.244
1.188GlnAsp: 1.188 ± 0.475
2.715GlnGlu: 2.715 ± 0.55
1.188GlnPhe: 1.188 ± 0.444
1.866GlnGly: 1.866 ± 0.581
1.527GlnHis: 1.527 ± 0.508
1.357GlnIle: 1.357 ± 0.62
2.375GlnLys: 2.375 ± 0.835
3.563GlnLeu: 3.563 ± 1.001
0.509GlnMet: 0.509 ± 0.315
2.206GlnAsn: 2.206 ± 0.332
1.527GlnPro: 1.527 ± 0.545
2.375GlnGln: 2.375 ± 0.464
2.545GlnArg: 2.545 ± 0.885
4.072GlnSer: 4.072 ± 0.823
2.715GlnThr: 2.715 ± 0.635
3.224GlnVal: 3.224 ± 1.033
0.509GlnTrp: 0.509 ± 0.275
1.018GlnTyr: 1.018 ± 0.321
0.0GlnXaa: 0.0 ± 0.0
Arg
4.581ArgAla: 4.581 ± 1.131
0.848ArgCys: 0.848 ± 0.427
2.884ArgAsp: 2.884 ± 0.755
3.563ArgGlu: 3.563 ± 0.781
2.036ArgPhe: 2.036 ± 0.5
4.581ArgGly: 4.581 ± 0.677
1.018ArgHis: 1.018 ± 0.558
1.697ArgIle: 1.697 ± 0.617
2.715ArgLys: 2.715 ± 0.708
5.769ArgLeu: 5.769 ± 1.047
1.697ArgMet: 1.697 ± 0.485
3.563ArgAsn: 3.563 ± 0.737
4.242ArgPro: 4.242 ± 1.124
3.393ArgGln: 3.393 ± 0.738
7.465ArgArg: 7.465 ± 2.83
3.733ArgSer: 3.733 ± 0.506
2.375ArgThr: 2.375 ± 1.005
4.581ArgVal: 4.581 ± 0.9
2.206ArgTrp: 2.206 ± 0.511
2.036ArgTyr: 2.036 ± 0.713
0.0ArgXaa: 0.0 ± 0.0
Ser
4.92SerAla: 4.92 ± 0.77
1.018SerCys: 1.018 ± 0.498
2.206SerAsp: 2.206 ± 0.617
4.242SerGlu: 4.242 ± 0.961
3.563SerPhe: 3.563 ± 1.002
5.599SerGly: 5.599 ± 0.889
1.697SerHis: 1.697 ± 0.546
4.751SerIle: 4.751 ± 0.694
3.733SerLys: 3.733 ± 1.187
5.769SerLeu: 5.769 ± 1.247
3.393SerMet: 3.393 ± 0.671
4.242SerAsn: 4.242 ± 0.945
3.393SerPro: 3.393 ± 0.613
3.563SerGln: 3.563 ± 0.878
4.751SerArg: 4.751 ± 1.397
5.429SerSer: 5.429 ± 1.313
2.036SerThr: 2.036 ± 0.455
4.072SerVal: 4.072 ± 1.005
1.527SerTrp: 1.527 ± 0.425
2.375SerTyr: 2.375 ± 0.803
0.0SerXaa: 0.0 ± 0.0
Thr
5.09ThrAla: 5.09 ± 1.328
1.188ThrCys: 1.188 ± 0.417
2.036ThrAsp: 2.036 ± 0.413
3.563ThrGlu: 3.563 ± 0.764
3.393ThrPhe: 3.393 ± 0.784
3.054ThrGly: 3.054 ± 0.715
1.188ThrHis: 1.188 ± 0.377
2.884ThrIle: 2.884 ± 0.786
2.375ThrLys: 2.375 ± 0.847
5.769ThrLeu: 5.769 ± 0.751
1.697ThrMet: 1.697 ± 0.442
2.715ThrAsn: 2.715 ± 0.732
4.581ThrPro: 4.581 ± 0.826
1.527ThrGln: 1.527 ± 0.396
2.206ThrArg: 2.206 ± 0.553
2.884ThrSer: 2.884 ± 1.011
3.902ThrThr: 3.902 ± 0.604
5.09ThrVal: 5.09 ± 0.696
0.679ThrTrp: 0.679 ± 0.352
2.375ThrTyr: 2.375 ± 0.959
0.0ThrXaa: 0.0 ± 0.0
Val
5.09ValAla: 5.09 ± 0.851
0.679ValCys: 0.679 ± 0.394
4.072ValAsp: 4.072 ± 1.014
5.26ValGlu: 5.26 ± 0.802
2.884ValPhe: 2.884 ± 0.569
2.545ValGly: 2.545 ± 0.656
1.018ValHis: 1.018 ± 0.435
1.866ValIle: 1.866 ± 0.513
2.545ValLys: 2.545 ± 0.978
5.26ValLeu: 5.26 ± 0.919
2.375ValMet: 2.375 ± 0.649
3.563ValAsn: 3.563 ± 1.049
4.072ValPro: 4.072 ± 0.683
3.733ValGln: 3.733 ± 0.698
4.581ValArg: 4.581 ± 1.159
6.278ValSer: 6.278 ± 1.548
6.278ValThr: 6.278 ± 0.84
5.938ValVal: 5.938 ± 1.198
0.509ValTrp: 0.509 ± 0.346
1.697ValTyr: 1.697 ± 0.603
0.0ValXaa: 0.0 ± 0.0
Trp
0.509TrpAla: 0.509 ± 0.213
0.0TrpCys: 0.0 ± 0.0
0.509TrpAsp: 0.509 ± 0.261
0.509TrpGlu: 0.509 ± 0.276
0.339TrpPhe: 0.339 ± 0.212
1.527TrpGly: 1.527 ± 0.477
0.17TrpHis: 0.17 ± 0.189
0.509TrpIle: 0.509 ± 0.305
0.339TrpLys: 0.339 ± 0.23
1.018TrpLeu: 1.018 ± 0.307
0.17TrpMet: 0.17 ± 0.165
0.679TrpAsn: 0.679 ± 0.264
0.679TrpPro: 0.679 ± 0.332
1.018TrpGln: 1.018 ± 0.507
0.509TrpArg: 0.509 ± 0.269
1.527TrpSer: 1.527 ± 0.702
0.679TrpThr: 0.679 ± 0.26
0.509TrpVal: 0.509 ± 0.342
0.0TrpTrp: 0.0 ± 0.0
0.679TrpTyr: 0.679 ± 0.338
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.357TyrAla: 1.357 ± 0.717
0.509TyrCys: 0.509 ± 0.321
1.188TyrAsp: 1.188 ± 0.328
2.545TyrGlu: 2.545 ± 0.613
1.527TyrPhe: 1.527 ± 0.656
1.018TyrGly: 1.018 ± 0.271
1.866TyrHis: 1.866 ± 0.609
1.527TyrIle: 1.527 ± 0.422
1.527TyrLys: 1.527 ± 0.444
3.563TyrLeu: 3.563 ± 0.756
1.188TyrMet: 1.188 ± 0.413
1.527TyrAsn: 1.527 ± 0.712
2.036TyrPro: 2.036 ± 0.537
2.375TyrGln: 2.375 ± 0.536
1.188TyrArg: 1.188 ± 0.376
2.884TyrSer: 2.884 ± 0.761
3.393TyrThr: 3.393 ± 0.652
1.188TyrVal: 1.188 ± 0.304
0.17TyrTrp: 0.17 ± 0.157
0.509TyrTyr: 0.509 ± 0.267
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 17 proteins (5895 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski