Amino acid dipepetide frequency for Rousettus aegyptiacus papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.587AlaAla: 5.587 ± 2.261
1.197AlaCys: 1.197 ± 0.601
3.591AlaAsp: 3.591 ± 1.704
4.789AlaGlu: 4.789 ± 1.392
1.995AlaPhe: 1.995 ± 0.853
5.188AlaGly: 5.188 ± 1.85
0.0AlaHis: 0.0 ± 0.0
3.99AlaIle: 3.99 ± 1.2
1.995AlaLys: 1.995 ± 0.651
6.784AlaLeu: 6.784 ± 1.062
1.995AlaMet: 1.995 ± 1.168
2.394AlaAsn: 2.394 ± 1.186
2.793AlaPro: 2.793 ± 0.664
5.986AlaGln: 5.986 ± 2.122
2.793AlaArg: 2.793 ± 0.627
3.99AlaSer: 3.99 ± 1.439
2.793AlaThr: 2.793 ± 0.645
5.986AlaVal: 5.986 ± 1.774
1.197AlaTrp: 1.197 ± 0.334
2.394AlaTyr: 2.394 ± 0.676
0.0AlaXaa: 0.0 ± 0.0
Cys
0.798CysAla: 0.798 ± 0.553
0.798CysCys: 0.798 ± 0.622
0.798CysAsp: 0.798 ± 0.553
1.197CysGlu: 1.197 ± 0.816
1.596CysPhe: 1.596 ± 0.751
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.798CysIle: 0.798 ± 0.453
1.596CysLys: 1.596 ± 0.706
1.596CysLeu: 1.596 ± 0.926
0.798CysMet: 0.798 ± 0.633
0.0CysAsn: 0.0 ± 0.0
1.995CysPro: 1.995 ± 0.64
0.399CysGln: 0.399 ± 0.416
0.798CysArg: 0.798 ± 0.679
2.394CysSer: 2.394 ± 0.795
2.394CysThr: 2.394 ± 1.634
1.197CysVal: 1.197 ± 0.397
0.399CysTrp: 0.399 ± 0.311
1.197CysTyr: 1.197 ± 0.782
0.0CysXaa: 0.0 ± 0.0
Asp
3.192AspAla: 3.192 ± 0.56
0.399AspCys: 0.399 ± 0.332
3.591AspAsp: 3.591 ± 0.647
5.188AspGlu: 5.188 ± 1.165
3.192AspPhe: 3.192 ± 0.949
5.986AspGly: 5.986 ± 1.705
0.798AspHis: 0.798 ± 0.438
3.192AspIle: 3.192 ± 1.033
3.192AspLys: 3.192 ± 1.24
4.789AspLeu: 4.789 ± 1.962
0.399AspMet: 0.399 ± 0.332
1.197AspAsn: 1.197 ± 0.44
6.784AspPro: 6.784 ± 2.515
1.995AspGln: 1.995 ± 0.671
4.789AspArg: 4.789 ± 1.235
3.591AspSer: 3.591 ± 1.578
4.789AspThr: 4.789 ± 1.102
3.192AspVal: 3.192 ± 0.877
0.798AspTrp: 0.798 ± 0.622
0.399AspTyr: 0.399 ± 0.308
0.0AspXaa: 0.0 ± 0.0
Glu
3.99GluAla: 3.99 ± 1.521
0.399GluCys: 0.399 ± 0.311
7.582GluAsp: 7.582 ± 1.978
8.38GluGlu: 8.38 ± 1.882
1.995GluPhe: 1.995 ± 0.853
5.587GluGly: 5.587 ± 1.661
0.798GluHis: 0.798 ± 0.453
2.793GluIle: 2.793 ± 1.243
2.793GluLys: 2.793 ± 1.339
3.591GluLeu: 3.591 ± 1.424
0.798GluMet: 0.798 ± 0.349
1.197GluAsn: 1.197 ± 0.44
2.793GluPro: 2.793 ± 0.828
3.591GluGln: 3.591 ± 1.143
3.99GluArg: 3.99 ± 0.903
3.192GluSer: 3.192 ± 0.605
3.192GluThr: 3.192 ± 1.37
6.385GluVal: 6.385 ± 1.122
0.399GluTrp: 0.399 ± 0.332
1.596GluTyr: 1.596 ± 0.515
0.0GluXaa: 0.0 ± 0.0
Phe
1.995PheAla: 1.995 ± 0.651
0.798PheCys: 0.798 ± 0.679
2.394PheAsp: 2.394 ± 0.884
0.798PheGlu: 0.798 ± 0.464
0.798PhePhe: 0.798 ± 0.375
3.99PheGly: 3.99 ± 0.854
1.197PheHis: 1.197 ± 0.764
0.798PheIle: 0.798 ± 0.375
1.995PheLys: 1.995 ± 0.802
2.793PheLeu: 2.793 ± 0.82
0.798PheMet: 0.798 ± 0.349
1.197PheAsn: 1.197 ± 0.677
1.197PhePro: 1.197 ± 0.654
0.798PheGln: 0.798 ± 0.389
1.995PheArg: 1.995 ± 0.39
1.596PheSer: 1.596 ± 0.725
0.798PheThr: 0.798 ± 0.634
1.596PheVal: 1.596 ± 0.626
1.197PheTrp: 1.197 ± 0.637
2.793PheTyr: 2.793 ± 1.176
0.0PheXaa: 0.0 ± 0.0
Gly
6.784GlyAla: 6.784 ± 1.165
1.197GlyCys: 1.197 ± 0.44
4.389GlyAsp: 4.389 ± 1.488
5.587GlyGlu: 5.587 ± 1.353
2.793GlyPhe: 2.793 ± 0.982
11.572GlyGly: 11.572 ± 2.568
1.995GlyHis: 1.995 ± 1.147
4.789GlyIle: 4.789 ± 1.637
2.793GlyLys: 2.793 ± 1.104
4.789GlyLeu: 4.789 ± 1.008
1.995GlyMet: 1.995 ± 0.991
4.389GlyAsn: 4.389 ± 1.35
4.389GlyPro: 4.389 ± 1.482
2.394GlyGln: 2.394 ± 1.068
6.385GlyArg: 6.385 ± 1.9
5.986GlySer: 5.986 ± 1.149
5.986GlyThr: 5.986 ± 1.771
5.188GlyVal: 5.188 ± 0.857
0.0GlyTrp: 0.0 ± 0.0
1.197GlyTyr: 1.197 ± 0.405
0.0GlyXaa: 0.0 ± 0.0
His
0.798HisAla: 0.798 ± 0.389
1.995HisCys: 1.995 ± 1.027
0.399HisAsp: 0.399 ± 0.308
1.596HisGlu: 1.596 ± 1.209
0.798HisPhe: 0.798 ± 0.438
0.798HisGly: 0.798 ± 0.375
0.399HisHis: 0.399 ± 0.308
1.197HisIle: 1.197 ± 0.405
0.798HisLys: 0.798 ± 0.53
1.995HisLeu: 1.995 ± 0.679
2.394HisMet: 2.394 ± 1.088
0.0HisAsn: 0.0 ± 0.0
1.995HisPro: 1.995 ± 0.679
0.798HisGln: 0.798 ± 0.53
1.995HisArg: 1.995 ± 0.951
0.798HisSer: 0.798 ± 0.389
1.995HisThr: 1.995 ± 0.865
1.197HisVal: 1.197 ± 0.405
0.399HisTrp: 0.399 ± 0.416
2.793HisTyr: 2.793 ± 1.086
0.0HisXaa: 0.0 ± 0.0
Ile
2.394IleAla: 2.394 ± 0.802
0.399IleCys: 0.399 ± 0.471
3.591IleAsp: 3.591 ± 1.396
4.389IleGlu: 4.389 ± 1.858
0.798IlePhe: 0.798 ± 0.622
2.394IleGly: 2.394 ± 1.234
0.798IleHis: 0.798 ± 0.349
2.793IleIle: 2.793 ± 0.919
1.596IleLys: 1.596 ± 0.884
3.591IleLeu: 3.591 ± 1.101
0.399IleMet: 0.399 ± 0.311
1.197IleAsn: 1.197 ± 0.617
5.188IlePro: 5.188 ± 1.684
1.995IleGln: 1.995 ± 0.806
1.596IleArg: 1.596 ± 0.782
2.394IleSer: 2.394 ± 0.952
2.394IleThr: 2.394 ± 1.074
4.789IleVal: 4.789 ± 1.378
0.0IleTrp: 0.0 ± 0.0
1.596IleTyr: 1.596 ± 0.762
0.0IleXaa: 0.0 ± 0.0
Lys
1.596LysAla: 1.596 ± 0.568
1.197LysCys: 1.197 ± 0.636
2.793LysAsp: 2.793 ± 1.501
2.394LysGlu: 2.394 ± 1.186
1.197LysPhe: 1.197 ± 0.604
1.995LysGly: 1.995 ± 1.215
3.192LysHis: 3.192 ± 1.347
1.197LysIle: 1.197 ± 0.604
2.793LysLys: 2.793 ± 1.217
1.995LysLeu: 1.995 ± 1.088
0.399LysMet: 0.399 ± 0.332
1.596LysAsn: 1.596 ± 0.884
2.394LysPro: 2.394 ± 1.989
0.798LysGln: 0.798 ± 0.375
3.591LysArg: 3.591 ± 0.676
4.389LysSer: 4.389 ± 1.343
2.394LysThr: 2.394 ± 1.021
1.197LysVal: 1.197 ± 0.637
0.399LysTrp: 0.399 ± 0.308
1.995LysTyr: 1.995 ± 0.856
0.0LysXaa: 0.0 ± 0.0
Leu
5.188LeuAla: 5.188 ± 1.357
1.596LeuCys: 1.596 ± 0.737
4.389LeuAsp: 4.389 ± 0.692
5.587LeuGlu: 5.587 ± 1.745
2.394LeuPhe: 2.394 ± 0.81
7.183LeuGly: 7.183 ± 1.992
2.793LeuHis: 2.793 ± 1.326
3.591LeuIle: 3.591 ± 1.223
3.192LeuLys: 3.192 ± 0.62
7.183LeuLeu: 7.183 ± 1.726
1.995LeuMet: 1.995 ± 0.745
1.596LeuAsn: 1.596 ± 0.966
3.591LeuPro: 3.591 ± 0.789
6.385LeuGln: 6.385 ± 1.19
7.183LeuArg: 7.183 ± 3.017
5.986LeuSer: 5.986 ± 1.13
5.188LeuThr: 5.188 ± 1.481
3.99LeuVal: 3.99 ± 1.269
0.798LeuTrp: 0.798 ± 0.665
2.394LeuTyr: 2.394 ± 0.98
0.0LeuXaa: 0.0 ± 0.0
Met
1.995MetAla: 1.995 ± 0.783
0.0MetCys: 0.0 ± 0.0
0.798MetAsp: 0.798 ± 0.634
1.995MetGlu: 1.995 ± 0.718
0.399MetPhe: 0.399 ± 0.311
0.798MetGly: 0.798 ± 0.389
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.798MetLys: 0.798 ± 0.622
2.793MetLeu: 2.793 ± 1.379
0.0MetMet: 0.0 ± 0.0
0.399MetAsn: 0.399 ± 0.332
1.197MetPro: 1.197 ± 0.405
1.197MetGln: 1.197 ± 0.585
2.793MetArg: 2.793 ± 1.217
1.596MetSer: 1.596 ± 0.721
1.596MetThr: 1.596 ± 0.944
1.197MetVal: 1.197 ± 0.933
0.0MetTrp: 0.0 ± 0.0
0.798MetTyr: 0.798 ± 0.665
0.0MetXaa: 0.0 ± 0.0
Asn
2.394AsnAla: 2.394 ± 0.435
1.197AsnCys: 1.197 ± 0.64
0.798AsnAsp: 0.798 ± 0.665
0.0AsnGlu: 0.0 ± 0.0
1.197AsnPhe: 1.197 ± 0.677
1.197AsnGly: 1.197 ± 0.997
0.0AsnHis: 0.0 ± 0.0
1.197AsnIle: 1.197 ± 0.542
1.197AsnLys: 1.197 ± 0.617
3.192AsnLeu: 3.192 ± 0.901
0.399AsnMet: 0.399 ± 0.311
0.798AsnAsn: 0.798 ± 0.389
4.389AsnPro: 4.389 ± 1.098
2.394AsnGln: 2.394 ± 1.261
2.793AsnArg: 2.793 ± 0.789
1.596AsnSer: 1.596 ± 0.944
1.197AsnThr: 1.197 ± 0.677
2.793AsnVal: 2.793 ± 0.846
0.798AsnTrp: 0.798 ± 0.375
0.798AsnTyr: 0.798 ± 0.453
0.0AsnXaa: 0.0 ± 0.0
Pro
7.981ProAla: 7.981 ± 1.714
0.798ProCys: 0.798 ± 0.813
3.99ProAsp: 3.99 ± 1.69
3.99ProGlu: 3.99 ± 0.939
0.798ProPhe: 0.798 ± 0.453
6.784ProGly: 6.784 ± 2.714
1.995ProHis: 1.995 ± 1.341
1.596ProIle: 1.596 ± 0.86
2.394ProLys: 2.394 ± 0.681
7.183ProLeu: 7.183 ± 2.078
0.399ProMet: 0.399 ± 0.308
2.394ProAsn: 2.394 ± 0.749
5.986ProPro: 5.986 ± 2.462
1.995ProGln: 1.995 ± 0.865
4.389ProArg: 4.389 ± 1.887
3.99ProSer: 3.99 ± 1.108
3.192ProThr: 3.192 ± 0.913
7.183ProVal: 7.183 ± 1.336
1.197ProTrp: 1.197 ± 0.405
2.394ProTyr: 2.394 ± 1.239
0.0ProXaa: 0.0 ± 0.0
Gln
5.188GlnAla: 5.188 ± 1.492
0.798GlnCys: 0.798 ± 0.566
5.587GlnAsp: 5.587 ± 1.496
2.394GlnGlu: 2.394 ± 1.637
0.798GlnPhe: 0.798 ± 0.375
3.192GlnGly: 3.192 ± 0.934
0.798GlnHis: 0.798 ± 0.438
1.995GlnIle: 1.995 ± 0.84
1.596GlnLys: 1.596 ± 0.562
3.99GlnLeu: 3.99 ± 1.473
1.197GlnMet: 1.197 ± 0.637
0.798GlnAsn: 0.798 ± 0.453
2.793GlnPro: 2.793 ± 0.941
2.793GlnGln: 2.793 ± 0.9
3.591GlnArg: 3.591 ± 1.477
2.793GlnSer: 2.793 ± 0.926
1.197GlnThr: 1.197 ± 0.764
4.389GlnVal: 4.389 ± 1.037
0.399GlnTrp: 0.399 ± 0.311
1.995GlnTyr: 1.995 ± 0.39
0.0GlnXaa: 0.0 ± 0.0
Arg
3.99ArgAla: 3.99 ± 0.862
1.197ArgCys: 1.197 ± 1.2
3.192ArgAsp: 3.192 ± 1.433
3.591ArgGlu: 3.591 ± 1.375
3.192ArgPhe: 3.192 ± 1.064
5.188ArgGly: 5.188 ± 1.215
3.591ArgHis: 3.591 ± 1.805
1.995ArgIle: 1.995 ± 0.672
3.192ArgLys: 3.192 ± 0.737
5.986ArgLeu: 5.986 ± 1.321
0.798ArgMet: 0.798 ± 0.367
3.591ArgAsn: 3.591 ± 0.58
4.789ArgPro: 4.789 ± 1.536
3.192ArgGln: 3.192 ± 1.132
5.188ArgArg: 5.188 ± 2.157
6.385ArgSer: 6.385 ± 1.551
3.591ArgThr: 3.591 ± 1.063
3.591ArgVal: 3.591 ± 0.651
0.0ArgTrp: 0.0 ± 0.0
1.596ArgTyr: 1.596 ± 0.562
0.0ArgXaa: 0.0 ± 0.0
Ser
3.99SerAla: 3.99 ± 0.546
1.596SerCys: 1.596 ± 1.16
3.591SerAsp: 3.591 ± 1.546
1.995SerGlu: 1.995 ± 0.614
2.394SerPhe: 2.394 ± 0.435
7.981SerGly: 7.981 ± 1.857
1.596SerHis: 1.596 ± 0.934
3.192SerIle: 3.192 ± 1.303
1.197SerLys: 1.197 ± 0.397
7.582SerLeu: 7.582 ± 1.127
1.197SerMet: 1.197 ± 0.472
1.995SerAsn: 1.995 ± 1.167
4.789SerPro: 4.789 ± 1.446
2.793SerGln: 2.793 ± 1.071
3.591SerArg: 3.591 ± 0.637
4.389SerSer: 4.389 ± 0.989
5.188SerThr: 5.188 ± 1.668
5.188SerVal: 5.188 ± 1.238
1.596SerTrp: 1.596 ± 0.876
0.798SerTyr: 0.798 ± 0.349
0.0SerXaa: 0.0 ± 0.0
Thr
3.192ThrAla: 3.192 ± 1.031
2.394ThrCys: 2.394 ± 0.638
3.591ThrAsp: 3.591 ± 1.071
5.188ThrGlu: 5.188 ± 1.335
2.394ThrPhe: 2.394 ± 1.16
3.99ThrGly: 3.99 ± 1.25
1.197ThrHis: 1.197 ± 0.617
2.394ThrIle: 2.394 ± 0.886
0.798ThrLys: 0.798 ± 0.375
3.99ThrLeu: 3.99 ± 1.303
1.995ThrMet: 1.995 ± 0.524
2.394ThrAsn: 2.394 ± 0.886
3.591ThrPro: 3.591 ± 1.051
3.591ThrGln: 3.591 ± 1.001
3.99ThrArg: 3.99 ± 0.965
4.389ThrSer: 4.389 ± 0.826
5.188ThrThr: 5.188 ± 1.363
3.591ThrVal: 3.591 ± 1.427
0.399ThrTrp: 0.399 ± 0.416
1.197ThrTyr: 1.197 ± 0.727
0.0ThrXaa: 0.0 ± 0.0
Val
3.591ValAla: 3.591 ± 0.813
1.995ValCys: 1.995 ± 0.619
4.389ValAsp: 4.389 ± 1.249
4.789ValGlu: 4.789 ± 1.092
1.197ValPhe: 1.197 ± 0.654
6.784ValGly: 6.784 ± 2.008
1.995ValHis: 1.995 ± 0.859
3.591ValIle: 3.591 ± 1.13
2.793ValLys: 2.793 ± 0.449
3.591ValLeu: 3.591 ± 1.004
0.798ValMet: 0.798 ± 0.464
1.995ValAsn: 1.995 ± 0.867
7.582ValPro: 7.582 ± 1.842
3.99ValGln: 3.99 ± 1.593
3.99ValArg: 3.99 ± 0.6
6.385ValSer: 6.385 ± 1.812
3.99ValThr: 3.99 ± 0.517
4.389ValVal: 4.389 ± 1.11
0.399ValTrp: 0.399 ± 0.332
2.394ValTyr: 2.394 ± 0.749
0.0ValXaa: 0.0 ± 0.0
Trp
0.399TrpAla: 0.399 ± 0.311
0.399TrpCys: 0.399 ± 0.308
0.399TrpAsp: 0.399 ± 0.332
0.399TrpGlu: 0.399 ± 0.416
0.399TrpPhe: 0.399 ± 0.308
1.995TrpGly: 1.995 ± 0.901
0.0TrpHis: 0.0 ± 0.0
0.798TrpIle: 0.798 ± 0.375
0.798TrpLys: 0.798 ± 0.622
2.793TrpLeu: 2.793 ± 1.142
0.0TrpMet: 0.0 ± 0.0
0.399TrpAsn: 0.399 ± 0.332
0.399TrpPro: 0.399 ± 0.308
0.798TrpGln: 0.798 ± 0.375
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.798TrpThr: 0.798 ± 0.453
0.798TrpVal: 0.798 ± 0.622
0.0TrpTrp: 0.0 ± 0.0
0.399TrpTyr: 0.399 ± 0.416
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.793TyrAla: 2.793 ± 1.037
0.399TyrCys: 0.399 ± 0.619
1.596TyrAsp: 1.596 ± 0.571
0.798TyrGlu: 0.798 ± 0.453
1.197TyrPhe: 1.197 ± 0.801
1.995TyrGly: 1.995 ± 0.653
1.995TyrHis: 1.995 ± 0.39
2.394TyrIle: 2.394 ± 0.649
1.995TyrLys: 1.995 ± 0.79
1.995TyrLeu: 1.995 ± 0.456
1.197TyrMet: 1.197 ± 0.397
0.798TyrAsn: 0.798 ± 0.529
1.995TyrPro: 1.995 ± 0.788
0.399TyrGln: 0.399 ± 0.524
2.394TyrArg: 2.394 ± 0.882
0.798TyrSer: 0.798 ± 0.438
1.596TyrThr: 1.596 ± 0.721
2.793TyrVal: 2.793 ± 1.022
1.596TyrTrp: 1.596 ± 0.275
1.197TyrTyr: 1.197 ± 0.636
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (2507 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski