Amino acid dipepetide frequency for Cotton leaf curl Shahdadpur virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.256AlaAla: 6.256 ± 1.8
0.894AlaCys: 0.894 ± 0.769
0.894AlaAsp: 0.894 ± 0.769
0.0AlaGlu: 0.0 ± 0.0
0.894AlaPhe: 0.894 ± 0.867
3.575AlaGly: 3.575 ± 0.923
2.681AlaHis: 2.681 ± 1.157
0.894AlaIle: 0.894 ± 0.626
2.681AlaLys: 2.681 ± 0.728
6.256AlaLeu: 6.256 ± 1.8
0.0AlaMet: 0.0 ± 0.0
2.681AlaAsn: 2.681 ± 1.038
3.575AlaPro: 3.575 ± 1.195
5.362AlaGln: 5.362 ± 1.716
5.362AlaArg: 5.362 ± 2.161
3.575AlaSer: 3.575 ± 2.247
3.575AlaThr: 3.575 ± 2.322
2.681AlaVal: 2.681 ± 1.157
1.787AlaTrp: 1.787 ± 0.665
1.787AlaTyr: 1.787 ± 0.665
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.787CysCys: 1.787 ± 1.641
0.894CysAsp: 0.894 ± 0.872
1.787CysGlu: 1.787 ± 1.032
0.894CysPhe: 0.894 ± 0.867
1.787CysGly: 1.787 ± 0.914
0.894CysHis: 0.894 ± 0.893
0.0CysIle: 0.0 ± 0.0
0.894CysLys: 0.894 ± 0.769
0.0CysLeu: 0.0 ± 0.0
1.787CysMet: 1.787 ± 1.106
1.787CysAsn: 1.787 ± 0.914
1.787CysPro: 1.787 ± 1.641
0.894CysGln: 0.894 ± 0.626
0.894CysArg: 0.894 ± 0.626
3.575CysSer: 3.575 ± 1.75
1.787CysThr: 1.787 ± 1.017
1.787CysVal: 1.787 ± 1.537
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.681AspAla: 2.681 ± 1.879
0.0AspCys: 0.0 ± 0.0
1.787AspAsp: 1.787 ± 0.914
2.681AspGlu: 2.681 ± 0.728
1.787AspPhe: 1.787 ± 0.665
2.681AspGly: 2.681 ± 1.879
0.894AspHis: 0.894 ± 0.893
2.681AspIle: 2.681 ± 1.644
1.787AspLys: 1.787 ± 0.665
5.362AspLeu: 5.362 ± 2.151
0.0AspMet: 0.0 ± 0.0
0.894AspAsn: 0.894 ± 0.769
3.575AspPro: 3.575 ± 1.75
2.681AspGln: 2.681 ± 1.114
3.575AspArg: 3.575 ± 1.329
4.468AspSer: 4.468 ± 1.362
2.681AspThr: 2.681 ± 1.628
5.362AspVal: 5.362 ± 1.67
1.787AspTrp: 1.787 ± 0.914
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.362GluAla: 5.362 ± 1.25
0.894GluCys: 0.894 ± 0.893
0.894GluAsp: 0.894 ± 0.626
7.149GluGlu: 7.149 ± 4.314
3.575GluPhe: 3.575 ± 1.884
5.362GluGly: 5.362 ± 1.707
0.894GluHis: 0.894 ± 0.867
0.894GluIle: 0.894 ± 0.867
1.787GluLys: 1.787 ± 0.921
2.681GluLeu: 2.681 ± 1.392
0.0GluMet: 0.0 ± 0.0
3.575GluAsn: 3.575 ± 2.021
3.575GluPro: 3.575 ± 0.991
3.575GluGln: 3.575 ± 1.749
0.0GluArg: 0.0 ± 0.0
4.468GluSer: 4.468 ± 1.744
0.0GluThr: 0.0 ± 0.0
2.681GluVal: 2.681 ± 1.244
2.681GluTrp: 2.681 ± 1.287
0.894GluTyr: 0.894 ± 0.893
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.894PheCys: 0.894 ± 0.769
3.575PheAsp: 3.575 ± 1.329
2.681PheGlu: 2.681 ± 0.835
1.787PhePhe: 1.787 ± 0.665
0.894PheGly: 0.894 ± 0.769
1.787PheHis: 1.787 ± 0.921
2.681PheIle: 2.681 ± 1.038
3.575PheLys: 3.575 ± 1.78
6.256PheLeu: 6.256 ± 1.54
0.894PheMet: 0.894 ± 0.626
3.575PheAsn: 3.575 ± 1.907
0.894PhePro: 0.894 ± 0.82
2.681PheGln: 2.681 ± 1.287
2.681PheArg: 2.681 ± 1.318
2.681PheSer: 2.681 ± 1.163
0.894PheThr: 0.894 ± 0.867
0.894PheVal: 0.894 ± 0.626
0.0PheTrp: 0.0 ± 0.0
0.894PheTyr: 0.894 ± 0.769
0.0PheXaa: 0.0 ± 0.0
Gly
2.681GlyAla: 2.681 ± 1.272
1.787GlyCys: 1.787 ± 1.017
1.787GlyAsp: 1.787 ± 1.253
4.468GlyGlu: 4.468 ± 0.994
0.894GlyPhe: 0.894 ± 0.82
3.575GlyGly: 3.575 ± 0.9
1.787GlyHis: 1.787 ± 0.914
2.681GlyIle: 2.681 ± 1.287
6.256GlyLys: 6.256 ± 2.547
6.256GlyLeu: 6.256 ± 1.647
0.0GlyMet: 0.0 ± 0.0
2.681GlyAsn: 2.681 ± 1.771
1.787GlyPro: 1.787 ± 1.253
3.575GlyGln: 3.575 ± 1.747
0.894GlyArg: 0.894 ± 0.626
2.681GlySer: 2.681 ± 1.287
6.256GlyThr: 6.256 ± 1.397
0.894GlyVal: 0.894 ± 0.867
0.0GlyTrp: 0.0 ± 0.0
0.894GlyTyr: 0.894 ± 0.82
0.0GlyXaa: 0.0 ± 0.0
His
1.787HisAla: 1.787 ± 1.032
1.787HisCys: 1.787 ± 1.156
2.681HisAsp: 2.681 ± 1.753
1.787HisGlu: 1.787 ± 0.921
3.575HisPhe: 3.575 ± 1.884
1.787HisGly: 1.787 ± 1.156
0.894HisHis: 0.894 ± 0.893
2.681HisIle: 2.681 ± 1.244
0.894HisLys: 0.894 ± 0.867
3.575HisLeu: 3.575 ± 1.407
0.0HisMet: 0.0 ± 0.0
2.681HisAsn: 2.681 ± 1.287
0.894HisPro: 0.894 ± 0.626
1.787HisGln: 1.787 ± 1.156
4.468HisArg: 4.468 ± 1.653
1.787HisSer: 1.787 ± 1.017
1.787HisThr: 1.787 ± 1.017
2.681HisVal: 2.681 ± 1.642
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
2.681IleCys: 2.681 ± 1.096
3.575IleAsp: 3.575 ± 1.807
0.894IleGlu: 0.894 ± 0.626
2.681IlePhe: 2.681 ± 1.879
0.894IleGly: 0.894 ± 0.769
0.894IleHis: 0.894 ± 0.893
2.681IleIle: 2.681 ± 1.644
5.362IleLys: 5.362 ± 1.417
1.787IleLeu: 1.787 ± 1.231
0.0IleMet: 0.0 ± 0.0
1.787IleAsn: 1.787 ± 1.247
0.894IlePro: 0.894 ± 0.626
6.256IleGln: 6.256 ± 1.54
6.256IleArg: 6.256 ± 1.754
5.362IleSer: 5.362 ± 1.507
2.681IleThr: 2.681 ± 1.272
1.787IleVal: 1.787 ± 0.665
2.681IleTrp: 2.681 ± 1.784
2.681IleTyr: 2.681 ± 0.797
0.0IleXaa: 0.0 ± 0.0
Lys
4.468LysAla: 4.468 ± 2.236
2.681LysCys: 2.681 ± 1.272
1.787LysAsp: 1.787 ± 1.253
4.468LysGlu: 4.468 ± 2.168
2.681LysPhe: 2.681 ± 0.797
2.681LysGly: 2.681 ± 1.163
0.894LysHis: 0.894 ± 0.626
2.681LysIle: 2.681 ± 1.644
1.787LysLys: 1.787 ± 0.665
0.0LysLeu: 0.0 ± 0.0
0.0LysMet: 0.0 ± 0.0
5.362LysAsn: 5.362 ± 2.075
2.681LysPro: 2.681 ± 1.293
0.0LysGln: 0.0 ± 0.0
3.575LysArg: 3.575 ± 1.186
6.256LysSer: 6.256 ± 1.611
3.575LysThr: 3.575 ± 0.991
4.468LysVal: 4.468 ± 1.861
0.894LysTrp: 0.894 ± 0.769
4.468LysTyr: 4.468 ± 1.024
0.0LysXaa: 0.0 ± 0.0
Leu
3.575LeuAla: 3.575 ± 1.395
2.681LeuCys: 2.681 ± 1.038
4.468LeuAsp: 4.468 ± 2.378
3.575LeuGlu: 3.575 ± 1.407
1.787LeuPhe: 1.787 ± 1.247
5.362LeuGly: 5.362 ± 1.654
2.681LeuHis: 2.681 ± 1.272
3.575LeuIle: 3.575 ± 1.681
4.468LeuLys: 4.468 ± 0.811
3.575LeuLeu: 3.575 ± 1.754
0.894LeuMet: 0.894 ± 0.769
6.256LeuAsn: 6.256 ± 1.231
0.894LeuPro: 0.894 ± 0.893
3.575LeuGln: 3.575 ± 1.287
4.468LeuArg: 4.468 ± 0.994
3.575LeuSer: 3.575 ± 1.407
7.149LeuThr: 7.149 ± 2.709
5.362LeuVal: 5.362 ± 1.817
0.0LeuTrp: 0.0 ± 0.0
3.575LeuTyr: 3.575 ± 1.527
0.0LeuXaa: 0.0 ± 0.0
Met
0.894MetAla: 0.894 ± 0.769
0.894MetCys: 0.894 ± 0.769
2.681MetAsp: 2.681 ± 1.784
0.0MetGlu: 0.0 ± 0.0
2.681MetPhe: 2.681 ± 1.756
2.681MetGly: 2.681 ± 1.096
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.787MetLeu: 1.787 ± 1.032
0.0MetMet: 0.0 ± 0.0
0.894MetAsn: 0.894 ± 0.769
0.894MetPro: 0.894 ± 0.626
0.0MetGln: 0.0 ± 0.0
1.787MetArg: 1.787 ± 0.914
0.894MetSer: 0.894 ± 0.769
0.894MetThr: 0.894 ± 0.872
0.0MetVal: 0.0 ± 0.0
1.787MetTrp: 1.787 ± 0.921
2.681MetTyr: 2.681 ± 1.644
0.0MetXaa: 0.0 ± 0.0
Asn
3.575AsnAla: 3.575 ± 1.58
0.894AsnCys: 0.894 ± 0.893
1.787AsnAsp: 1.787 ± 1.253
1.787AsnGlu: 1.787 ± 1.032
1.787AsnPhe: 1.787 ± 1.017
1.787AsnGly: 1.787 ± 0.89
3.575AsnHis: 3.575 ± 1.61
3.575AsnIle: 3.575 ± 0.958
0.0AsnLys: 0.0 ± 0.0
4.468AsnLeu: 4.468 ± 1.808
4.468AsnMet: 4.468 ± 1.133
1.787AsnAsn: 1.787 ± 1.066
5.362AsnPro: 5.362 ± 1.608
1.787AsnGln: 1.787 ± 0.665
4.468AsnArg: 4.468 ± 1.771
2.681AsnSer: 2.681 ± 0.994
2.681AsnThr: 2.681 ± 1.272
3.575AsnVal: 3.575 ± 0.958
0.894AsnTrp: 0.894 ± 0.626
4.468AsnTyr: 4.468 ± 1.024
0.0AsnXaa: 0.0 ± 0.0
Pro
2.681ProAla: 2.681 ± 1.756
1.787ProCys: 1.787 ± 1.156
2.681ProAsp: 2.681 ± 1.698
0.894ProGlu: 0.894 ± 0.626
1.787ProPhe: 1.787 ± 0.89
0.894ProGly: 0.894 ± 0.626
4.468ProHis: 4.468 ± 2.465
3.575ProIle: 3.575 ± 1.42
3.575ProLys: 3.575 ± 2.505
4.468ProLeu: 4.468 ± 1.381
1.787ProMet: 1.787 ± 1.154
3.575ProAsn: 3.575 ± 1.308
1.787ProPro: 1.787 ± 0.921
5.362ProGln: 5.362 ± 1.608
3.575ProArg: 3.575 ± 1.61
4.468ProSer: 4.468 ± 1.484
3.575ProThr: 3.575 ± 1.957
3.575ProVal: 3.575 ± 1.186
0.0ProTrp: 0.0 ± 0.0
1.787ProTyr: 1.787 ± 0.665
0.0ProXaa: 0.0 ± 0.0
Gln
3.575GlnAla: 3.575 ± 1.379
0.0GlnCys: 0.0 ± 0.0
4.468GlnAsp: 4.468 ± 2.198
3.575GlnGlu: 3.575 ± 1.195
1.787GlnPhe: 1.787 ± 0.89
1.787GlnGly: 1.787 ± 1.253
4.468GlnHis: 4.468 ± 2.424
2.681GlnIle: 2.681 ± 1.287
1.787GlnLys: 1.787 ± 1.641
3.575GlnLeu: 3.575 ± 1.681
0.0GlnMet: 0.0 ± 0.0
1.787GlnAsn: 1.787 ± 0.914
4.468GlnPro: 4.468 ± 2.139
4.468GlnGln: 4.468 ± 0.97
1.787GlnArg: 1.787 ± 0.979
6.256GlnSer: 6.256 ± 1.787
3.575GlnThr: 3.575 ± 1.78
4.468GlnVal: 4.468 ± 1.555
0.0GlnTrp: 0.0 ± 0.0
1.787GlnTyr: 1.787 ± 1.066
0.0GlnXaa: 0.0 ± 0.0
Arg
1.787ArgAla: 1.787 ± 1.032
2.681ArgCys: 2.681 ± 1.795
3.575ArgAsp: 3.575 ± 1.315
3.575ArgGlu: 3.575 ± 2.457
2.681ArgPhe: 2.681 ± 0.835
4.468ArgGly: 4.468 ± 1.07
1.787ArgHis: 1.787 ± 1.032
5.362ArgIle: 5.362 ± 1.399
2.681ArgLys: 2.681 ± 1.644
1.787ArgLeu: 1.787 ± 1.154
1.787ArgMet: 1.787 ± 1.537
3.575ArgAsn: 3.575 ± 1.209
6.256ArgPro: 6.256 ± 1.747
2.681ArgGln: 2.681 ± 1.356
6.256ArgArg: 6.256 ± 3.717
6.256ArgSer: 6.256 ± 1.907
4.468ArgThr: 4.468 ± 1.771
5.362ArgVal: 5.362 ± 1.803
0.0ArgTrp: 0.0 ± 0.0
1.787ArgTyr: 1.787 ± 1.032
0.0ArgXaa: 0.0 ± 0.0
Ser
2.681SerAla: 2.681 ± 1.392
0.0SerCys: 0.0 ± 0.0
2.681SerAsp: 2.681 ± 0.728
6.256SerGlu: 6.256 ± 1.533
3.575SerPhe: 3.575 ± 1.013
2.681SerGly: 2.681 ± 1.163
2.681SerHis: 2.681 ± 1.114
4.468SerIle: 4.468 ± 1.851
8.043SerLys: 8.043 ± 1.336
3.575SerLeu: 3.575 ± 1.407
2.681SerMet: 2.681 ± 1.494
3.575SerAsn: 3.575 ± 1.195
8.043SerPro: 8.043 ± 1.211
2.681SerGln: 2.681 ± 1.096
8.937SerArg: 8.937 ± 1.349
16.086SerSer: 16.086 ± 6.976
5.362SerThr: 5.362 ± 2.795
2.681SerVal: 2.681 ± 2.306
0.0SerTrp: 0.0 ± 0.0
2.681SerTyr: 2.681 ± 1.287
0.0SerXaa: 0.0 ± 0.0
Thr
6.256ThrAla: 6.256 ± 1.533
0.894ThrCys: 0.894 ± 0.872
0.0ThrAsp: 0.0 ± 0.0
0.894ThrGlu: 0.894 ± 0.872
0.0ThrPhe: 0.0 ± 0.0
5.362ThrGly: 5.362 ± 1.737
4.468ThrHis: 4.468 ± 2.722
1.787ThrIle: 1.787 ± 0.89
3.575ThrLys: 3.575 ± 1.329
6.256ThrLeu: 6.256 ± 1.48
1.787ThrMet: 1.787 ± 0.89
3.575ThrAsn: 3.575 ± 1.288
4.468ThrPro: 4.468 ± 1.12
1.787ThrGln: 1.787 ± 1.247
3.575ThrArg: 3.575 ± 1.865
3.575ThrSer: 3.575 ± 1.754
1.787ThrThr: 1.787 ± 1.734
2.681ThrVal: 2.681 ± 1.624
0.894ThrTrp: 0.894 ± 0.872
3.575ThrTyr: 3.575 ± 1.209
0.0ThrXaa: 0.0 ± 0.0
Val
0.894ValAla: 0.894 ± 0.769
0.0ValCys: 0.0 ± 0.0
4.468ValAsp: 4.468 ± 0.811
2.681ValGlu: 2.681 ± 1.905
2.681ValPhe: 2.681 ± 1.259
0.894ValGly: 0.894 ± 0.769
1.787ValHis: 1.787 ± 1.032
6.256ValIle: 6.256 ± 2.725
5.362ValLys: 5.362 ± 1.81
5.362ValLeu: 5.362 ± 1.594
1.787ValMet: 1.787 ± 1.537
1.787ValAsn: 1.787 ± 1.066
3.575ValPro: 3.575 ± 0.854
5.362ValGln: 5.362 ± 1.88
2.681ValArg: 2.681 ± 2.306
4.468ValSer: 4.468 ± 1.448
3.575ValThr: 3.575 ± 3.075
0.894ValVal: 0.894 ± 0.626
0.0ValTrp: 0.0 ± 0.0
2.681ValTyr: 2.681 ± 1.293
0.0ValXaa: 0.0 ± 0.0
Trp
2.681TrpAla: 2.681 ± 1.038
0.0TrpCys: 0.0 ± 0.0
0.894TrpAsp: 0.894 ± 0.82
0.894TrpGlu: 0.894 ± 0.867
0.0TrpPhe: 0.0 ± 0.0
0.894TrpGly: 0.894 ± 0.626
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.894TrpMet: 0.894 ± 0.769
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.894TrpGln: 0.894 ± 0.626
0.894TrpArg: 0.894 ± 0.893
1.787TrpSer: 1.787 ± 1.228
0.894TrpThr: 0.894 ± 0.867
0.894TrpVal: 0.894 ± 0.626
0.0TrpTrp: 0.0 ± 0.0
1.787TrpTyr: 1.787 ± 0.665
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.575TyrAla: 3.575 ± 2.021
0.0TyrCys: 0.0 ± 0.0
1.787TyrAsp: 1.787 ± 1.032
0.894TyrGlu: 0.894 ± 0.769
2.681TyrPhe: 2.681 ± 0.797
1.787TyrGly: 1.787 ± 0.914
0.0TyrHis: 0.0 ± 0.0
2.681TyrIle: 2.681 ± 1.879
0.894TyrLys: 0.894 ± 0.626
4.468TyrLeu: 4.468 ± 1.888
1.787TyrMet: 1.787 ± 1.027
4.468TyrAsn: 4.468 ± 1.664
0.894TyrPro: 0.894 ± 0.626
0.894TyrGln: 0.894 ± 0.769
2.681TyrArg: 2.681 ± 1.756
4.468TyrSer: 4.468 ± 1.827
0.0TyrThr: 0.0 ± 0.0
4.468TyrVal: 4.468 ± 2.37
0.0TyrTrp: 0.0 ± 0.0
0.894TyrTyr: 0.894 ± 0.893
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1120 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski