Amino acid dipepetide frequency for Dactylellina haptotyla (strain CBS 200.50) (Nematode-trapping fungus) (Monacrosporium haptotylum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.175AlaAla: 8.175 ± 0.053	0.95AlaCys: 0.95 ± 0.015	3.848AlaAsp: 3.848 ± 0.027	4.728AlaGlu: 4.728 ± 0.039	2.795AlaPhe: 2.795 ± 0.026	5.439AlaGly: 5.439 ± 0.042	1.387AlaHis: 1.387 ± 0.018	4.28AlaIle: 4.28 ± 0.031	4.204AlaLys: 4.204 ± 0.036	6.593AlaLeu: 6.593 ± 0.039	1.728AlaMet: 1.728 ± 0.018	2.991AlaAsn: 2.991 ± 0.023	4.6AlaPro: 4.6 ± 0.037	2.88AlaGln: 2.88 ± 0.029	4.043AlaArg: 4.043 ± 0.032	6.66AlaSer: 6.66 ± 0.039	5.42AlaThr: 5.42 ± 0.045	4.855AlaVal: 4.855 ± 0.034	0.944AlaTrp: 0.944 ± 0.015	2.062AlaTyr: 2.062 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.842CysAla: 0.842 ± 0.013	0.238CysCys: 0.238 ± 0.008	0.651CysAsp: 0.651 ± 0.012	0.617CysGlu: 0.617 ± 0.013	0.525CysPhe: 0.525 ± 0.01	0.962CysGly: 0.962 ± 0.017	0.271CysHis: 0.271 ± 0.008	0.686CysIle: 0.686 ± 0.013	0.612CysLys: 0.612 ± 0.012	1.131CysLeu: 1.131 ± 0.015	0.251CysMet: 0.251 ± 0.007	0.48CysAsn: 0.48 ± 0.012	0.672CysPro: 0.672 ± 0.015	0.43CysGln: 0.43 ± 0.009	0.649CysArg: 0.649 ± 0.012	0.893CysSer: 0.893 ± 0.014	0.698CysThr: 0.698 ± 0.013	0.734CysVal: 0.734 ± 0.014	0.191CysTrp: 0.191 ± 0.006	0.4CysTyr: 0.4 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.174AspAla: 4.174 ± 0.03	0.658AspCys: 0.658 ± 0.011	4.471AspAsp: 4.471 ± 0.043	4.637AspGlu: 4.637 ± 0.041	2.245AspPhe: 2.245 ± 0.02	4.098AspGly: 4.098 ± 0.038	1.062AspHis: 1.062 ± 0.015	3.621AspIle: 3.621 ± 0.027	2.646AspLys: 2.646 ± 0.025	4.896AspLeu: 4.896 ± 0.033	1.244AspMet: 1.244 ± 0.013	2.046AspAsn: 2.046 ± 0.021	3.274AspPro: 3.274 ± 0.025	1.733AspGln: 1.733 ± 0.018	2.763AspArg: 2.763 ± 0.031	4.183AspSer: 4.183 ± 0.03	3.193AspThr: 3.193 ± 0.028	3.408AspVal: 3.408 ± 0.026	0.876AspTrp: 0.876 ± 0.013	1.746AspTyr: 1.746 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	4.865GluAla: 4.865 ± 0.032	0.618GluCys: 0.618 ± 0.01	4.459GluAsp: 4.459 ± 0.039	6.139GluGlu: 6.139 ± 0.071	2.209GluPhe: 2.209 ± 0.02	3.72GluGly: 3.72 ± 0.033	1.25GluHis: 1.25 ± 0.016	3.609GluIle: 3.609 ± 0.025	4.192GluLys: 4.192 ± 0.034	5.142GluLeu: 5.142 ± 0.037	1.495GluMet: 1.495 ± 0.018	2.684GluAsn: 2.684 ± 0.026	2.84GluPro: 2.84 ± 0.032	2.241GluGln: 2.241 ± 0.024	3.725GluArg: 3.725 ± 0.038	4.309GluSer: 4.309 ± 0.034	3.755GluThr: 3.755 ± 0.034	3.57GluVal: 3.57 ± 0.032	0.858GluTrp: 0.858 ± 0.015	1.917GluTyr: 1.917 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.788PheAla: 2.788 ± 0.026	0.547PheCys: 0.547 ± 0.012	2.29PheAsp: 2.29 ± 0.023	2.301PheGlu: 2.301 ± 0.023	1.563PhePhe: 1.563 ± 0.021	2.843PheGly: 2.843 ± 0.028	0.852PheHis: 0.852 ± 0.015	1.862PheIle: 1.862 ± 0.02	1.85PheLys: 1.85 ± 0.02	3.346PheLeu: 3.346 ± 0.033	0.789PheMet: 0.789 ± 0.012	1.544PheAsn: 1.544 ± 0.017	2.008PhePro: 2.008 ± 0.022	1.411PheGln: 1.411 ± 0.016	1.892PheArg: 1.892 ± 0.018	3.059PheSer: 3.059 ± 0.023	2.308PheThr: 2.308 ± 0.025	2.237PheVal: 2.237 ± 0.019	0.613PheTrp: 0.613 ± 0.01	1.181PheTyr: 1.181 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	4.922GlyAla: 4.922 ± 0.039	0.875GlyCys: 0.875 ± 0.016	3.683GlyAsp: 3.683 ± 0.032	3.646GlyGlu: 3.646 ± 0.028	2.778GlyPhe: 2.778 ± 0.027	6.191GlyGly: 6.191 ± 0.066	1.415GlyHis: 1.415 ± 0.019	3.695GlyIle: 3.695 ± 0.031	3.764GlyLys: 3.764 ± 0.03	5.409GlyLeu: 5.409 ± 0.035	1.513GlyMet: 1.513 ± 0.018	2.896GlyAsn: 2.896 ± 0.028	3.178GlyPro: 3.178 ± 0.04	2.267GlyGln: 2.267 ± 0.023	3.674GlyArg: 3.674 ± 0.034	5.87GlySer: 5.87 ± 0.047	4.219GlyThr: 4.219 ± 0.045	4.261GlyVal: 4.261 ± 0.031	1.093GlyTrp: 1.093 ± 0.015	2.323GlyTyr: 2.323 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	1.447HisAla: 1.447 ± 0.018	0.283HisCys: 0.283 ± 0.008	1.116HisAsp: 1.116 ± 0.016	1.168HisGlu: 1.168 ± 0.015	0.845HisPhe: 0.845 ± 0.012	1.446HisGly: 1.446 ± 0.017	0.859HisHis: 0.859 ± 0.018	1.235HisIle: 1.235 ± 0.015	0.978HisLys: 0.978 ± 0.015	2.0HisLeu: 2.0 ± 0.022	0.465HisMet: 0.465 ± 0.011	0.832HisAsn: 0.832 ± 0.014	1.514HisPro: 1.514 ± 0.02	0.916HisGln: 0.916 ± 0.015	1.344HisArg: 1.344 ± 0.018	1.629HisSer: 1.629 ± 0.02	1.209HisThr: 1.209 ± 0.016	1.134HisVal: 1.134 ± 0.016	0.297HisTrp: 0.297 ± 0.008	0.652HisTyr: 0.652 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.195IleAla: 4.195 ± 0.03	0.768IleCys: 0.768 ± 0.014	3.161IleAsp: 3.161 ± 0.024	3.236IleGlu: 3.236 ± 0.028	2.167IlePhe: 2.167 ± 0.023	3.265IleGly: 3.265 ± 0.024	1.193IleHis: 1.193 ± 0.014	2.935IleIle: 2.935 ± 0.027	2.778IleLys: 2.778 ± 0.025	4.903IleLeu: 4.903 ± 0.035	1.04IleMet: 1.04 ± 0.014	2.141IleAsn: 2.141 ± 0.018	3.46IlePro: 3.46 ± 0.024	2.021IleGln: 2.021 ± 0.018	2.918IleArg: 2.918 ± 0.026	4.499IleSer: 4.499 ± 0.032	3.69IleThr: 3.69 ± 0.064	3.316IleVal: 3.316 ± 0.026	0.75IleTrp: 0.75 ± 0.013	1.617IleTyr: 1.617 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.31LysAla: 4.31 ± 0.033	0.605LysCys: 0.605 ± 0.011	3.167LysAsp: 3.167 ± 0.029	3.903LysGlu: 3.903 ± 0.036	1.824LysPhe: 1.824 ± 0.017	3.236LysGly: 3.236 ± 0.027	1.163LysHis: 1.163 ± 0.015	2.902LysIle: 2.902 ± 0.025	4.168LysLys: 4.168 ± 0.049	4.581LysLeu: 4.581 ± 0.035	1.158LysMet: 1.158 ± 0.015	2.181LysAsn: 2.181 ± 0.023	3.054LysPro: 3.054 ± 0.029	1.947LysGln: 1.947 ± 0.022	3.649LysArg: 3.649 ± 0.03	3.959LysSer: 3.959 ± 0.031	3.407LysThr: 3.407 ± 0.033	3.102LysVal: 3.102 ± 0.026	0.743LysTrp: 0.743 ± 0.012	1.707LysTyr: 1.707 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	6.858LeuAla: 6.858 ± 0.041	1.054LeuCys: 1.054 ± 0.014	4.934LeuAsp: 4.934 ± 0.038	5.695LeuGlu: 5.695 ± 0.037	3.117LeuPhe: 3.117 ± 0.028	5.342LeuGly: 5.342 ± 0.036	1.952LeuHis: 1.952 ± 0.021	3.953LeuIle: 3.953 ± 0.032	4.738LeuLys: 4.738 ± 0.034	7.655LeuLeu: 7.655 ± 0.058	1.685LeuMet: 1.685 ± 0.017	3.335LeuAsn: 3.335 ± 0.029	5.36LeuPro: 5.36 ± 0.047	3.573LeuGln: 3.573 ± 0.033	5.054LeuArg: 5.054 ± 0.036	6.928LeuSer: 6.928 ± 0.038	4.869LeuThr: 4.869 ± 0.035	4.924LeuVal: 4.924 ± 0.036	1.089LeuTrp: 1.089 ± 0.015	2.344LeuTyr: 2.344 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	1.915MetAla: 1.915 ± 0.018	0.218MetCys: 0.218 ± 0.006	1.242MetAsp: 1.242 ± 0.016	1.396MetGlu: 1.396 ± 0.017	0.731MetPhe: 0.731 ± 0.012	1.409MetGly: 1.409 ± 0.017	0.429MetHis: 0.429 ± 0.01	1.027MetIle: 1.027 ± 0.014	1.221MetLys: 1.221 ± 0.016	1.707MetLeu: 1.707 ± 0.018	0.578MetMet: 0.578 ± 0.011	0.845MetAsn: 0.845 ± 0.014	1.193MetPro: 1.193 ± 0.016	0.815MetGln: 0.815 ± 0.013	1.134MetArg: 1.134 ± 0.015	1.753MetSer: 1.753 ± 0.018	1.218MetThr: 1.218 ± 0.016	1.293MetVal: 1.293 ± 0.016	0.258MetTrp: 0.258 ± 0.007	0.524MetTyr: 0.524 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.035AsnAla: 3.035 ± 0.026	0.521AsnCys: 0.521 ± 0.011	2.029AsnAsp: 2.029 ± 0.019	2.172AsnGlu: 2.172 ± 0.022	1.6AsnPhe: 1.6 ± 0.019	3.243AsnGly: 3.243 ± 0.032	0.882AsnHis: 0.882 ± 0.015	2.528AsnIle: 2.528 ± 0.024	1.889AsnLys: 1.889 ± 0.02	3.606AsnLeu: 3.606 ± 0.031	0.91AsnMet: 0.91 ± 0.015	1.853AsnAsn: 1.853 ± 0.023	2.814AsnPro: 2.814 ± 0.027	1.476AsnGln: 1.476 ± 0.019	2.067AsnArg: 2.067 ± 0.022	3.249AsnSer: 3.249 ± 0.03	2.611AsnThr: 2.611 ± 0.025	2.363AsnVal: 2.363 ± 0.02	0.594AsnTrp: 0.594 ± 0.01	1.261AsnTyr: 1.261 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	5.043ProAla: 5.043 ± 0.042	0.451ProCys: 0.451 ± 0.011	3.072ProAsp: 3.072 ± 0.024	3.774ProGlu: 3.774 ± 0.033	2.0ProPhe: 2.0 ± 0.02	3.912ProGly: 3.912 ± 0.039	1.196ProHis: 1.196 ± 0.016	2.906ProIle: 2.906 ± 0.027	3.101ProLys: 3.101 ± 0.031	4.492ProLeu: 4.492 ± 0.031	1.043ProMet: 1.043 ± 0.015	2.474ProAsn: 2.474 ± 0.025	5.764ProPro: 5.764 ± 0.072	2.489ProGln: 2.489 ± 0.03	3.088ProArg: 3.088 ± 0.03	5.875ProSer: 5.875 ± 0.051	4.663ProThr: 4.663 ± 0.046	3.664ProVal: 3.664 ± 0.035	0.655ProTrp: 0.655 ± 0.011	1.616ProTyr: 1.616 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	2.926GlnAla: 2.926 ± 0.028	0.448GlnCys: 0.448 ± 0.01	1.91GlnAsp: 1.91 ± 0.019	2.308GlnGlu: 2.308 ± 0.025	1.315GlnPhe: 1.315 ± 0.015	2.118GlnGly: 2.118 ± 0.023	0.909GlnHis: 0.909 ± 0.014	2.029GlnIle: 2.029 ± 0.02	2.153GlnLys: 2.153 ± 0.021	3.17GlnLeu: 3.17 ± 0.03	0.852GlnMet: 0.852 ± 0.015	1.747GlnAsn: 1.747 ± 0.021	2.455GlnPro: 2.455 ± 0.031	2.465GlnGln: 2.465 ± 0.062	2.254GlnArg: 2.254 ± 0.025	2.932GlnSer: 2.932 ± 0.028	2.356GlnThr: 2.356 ± 0.027	2.056GlnVal: 2.056 ± 0.021	0.494GlnTrp: 0.494 ± 0.012	1.184GlnTyr: 1.184 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	3.831ArgAla: 3.831 ± 0.032	0.636ArgCys: 0.636 ± 0.013	3.132ArgAsp: 3.132 ± 0.031	3.622ArgGlu: 3.622 ± 0.038	2.034ArgPhe: 2.034 ± 0.021	3.454ArgGly: 3.454 ± 0.033	1.324ArgHis: 1.324 ± 0.018	2.935ArgIle: 2.935 ± 0.027	3.63ArgLys: 3.63 ± 0.033	4.803ArgLeu: 4.803 ± 0.036	1.23ArgMet: 1.23 ± 0.016	2.368ArgAsn: 2.368 ± 0.02	3.08ArgPro: 3.08 ± 0.028	2.28ArgGln: 2.28 ± 0.025	4.573ArgArg: 4.573 ± 0.048	4.363ArgSer: 4.363 ± 0.04	3.193ArgThr: 3.193 ± 0.027	2.998ArgVal: 2.998 ± 0.021	0.8ArgTrp: 0.8 ± 0.014	1.705ArgTyr: 1.705 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.198SerAla: 6.198 ± 0.045	0.876SerCys: 0.876 ± 0.013	4.251SerAsp: 4.251 ± 0.032	4.269SerGlu: 4.269 ± 0.037	3.012SerPhe: 3.012 ± 0.024	5.723SerGly: 5.723 ± 0.043	1.792SerHis: 1.792 ± 0.02	4.453SerIle: 4.453 ± 0.031	4.183SerLys: 4.183 ± 0.034	6.879SerLeu: 6.879 ± 0.035	1.62SerMet: 1.62 ± 0.017	3.425SerAsn: 3.425 ± 0.028	5.535SerPro: 5.535 ± 0.052	3.153SerGln: 3.153 ± 0.03	4.611SerArg: 4.611 ± 0.035	9.297SerSer: 9.297 ± 0.094	6.298SerThr: 6.298 ± 0.07	4.552SerVal: 4.552 ± 0.033	1.013SerTrp: 1.013 ± 0.016	2.233SerTyr: 2.233 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.338ThrAla: 5.338 ± 0.043	0.819ThrCys: 0.819 ± 0.016	3.249ThrAsp: 3.249 ± 0.038	3.424ThrGlu: 3.424 ± 0.034	2.339ThrPhe: 2.339 ± 0.024	4.387ThrGly: 4.387 ± 0.041	1.199ThrHis: 1.199 ± 0.014	3.843ThrIle: 3.843 ± 0.058	3.217ThrLys: 3.217 ± 0.027	5.271ThrLeu: 5.271 ± 0.049	1.144ThrMet: 1.144 ± 0.013	2.513ThrAsn: 2.513 ± 0.024	4.757ThrPro: 4.757 ± 0.039	2.136ThrGln: 2.136 ± 0.027	3.08ThrArg: 3.08 ± 0.028	6.18ThrSer: 6.18 ± 0.082	6.429ThrThr: 6.429 ± 0.16	4.369ThrVal: 4.369 ± 0.06	0.81ThrTrp: 0.81 ± 0.014	1.794ThrTyr: 1.794 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	4.763ValAla: 4.763 ± 0.031	0.739ValCys: 0.739 ± 0.012	3.585ValAsp: 3.585 ± 0.027	4.033ValGlu: 4.033 ± 0.04	2.347ValPhe: 2.347 ± 0.024	3.828ValGly: 3.828 ± 0.03	1.202ValHis: 1.202 ± 0.014	3.199ValIle: 3.199 ± 0.03	3.202ValLys: 3.202 ± 0.028	4.983ValLeu: 4.983 ± 0.033	1.213ValMet: 1.213 ± 0.017	2.345ValAsn: 2.345 ± 0.022	3.532ValPro: 3.532 ± 0.03	2.146ValGln: 2.146 ± 0.02	3.053ValArg: 3.053 ± 0.023	4.522ValSer: 4.522 ± 0.032	4.039ValThr: 4.039 ± 0.058	4.174ValVal: 4.174 ± 0.035	0.788ValTrp: 0.788 ± 0.014	1.813ValTyr: 1.813 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	0.937TrpAla: 0.937 ± 0.015	0.199TrpCys: 0.199 ± 0.007	0.911TrpAsp: 0.911 ± 0.014	0.858TrpGlu: 0.858 ± 0.011	0.537TrpPhe: 0.537 ± 0.009	0.91TrpGly: 0.91 ± 0.015	0.295TrpHis: 0.295 ± 0.007	0.73TrpIle: 0.73 ± 0.011	0.861TrpLys: 0.861 ± 0.013	1.158TrpLeu: 1.158 ± 0.017	0.349TrpMet: 0.349 ± 0.008	0.632TrpAsn: 0.632 ± 0.01	0.523TrpPro: 0.523 ± 0.01	0.503TrpGln: 0.503 ± 0.012	0.833TrpArg: 0.833 ± 0.014	0.955TrpSer: 0.955 ± 0.015	0.829TrpThr: 0.829 ± 0.013	0.839TrpVal: 0.839 ± 0.012	0.274TrpTrp: 0.274 ± 0.008	0.45TrpTyr: 0.45 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.019TyrAla: 2.019 ± 0.022	0.428TyrCys: 0.428 ± 0.009	1.812TyrAsp: 1.812 ± 0.019	1.67TyrGlu: 1.67 ± 0.017	1.302TyrPhe: 1.302 ± 0.017	2.147TyrGly: 2.147 ± 0.023	0.739TyrHis: 0.739 ± 0.012	1.625TyrIle: 1.625 ± 0.019	1.38TyrLys: 1.38 ± 0.016	2.737TyrLeu: 2.737 ± 0.025	0.603TyrMet: 0.603 ± 0.01	1.37TyrAsn: 1.37 ± 0.018	1.663TyrPro: 1.663 ± 0.023	1.197TyrGln: 1.197 ± 0.019	1.588TyrArg: 1.588 ± 0.019	2.258TyrSer: 2.258 ± 0.023	1.891TyrThr: 1.891 ± 0.024	1.654TyrVal: 1.654 ± 0.018	0.445TyrTrp: 0.445 ± 0.009	1.068TyrTyr: 1.068 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 10959 proteins (5669352 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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