Amino acid dipepetide frequency for Eumeta variegata (Bagworm moth) (Eumeta japonica)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.792AlaAla: 8.792 ± 0.04	1.664AlaCys: 1.664 ± 0.01	3.43AlaAsp: 3.43 ± 0.016	3.829AlaGlu: 3.829 ± 0.016	2.397AlaPhe: 2.397 ± 0.011	5.467AlaGly: 5.467 ± 0.054	2.173AlaHis: 2.173 ± 0.011	3.322AlaIle: 3.322 ± 0.014	3.137AlaLys: 3.137 ± 0.016	7.163AlaLeu: 7.163 ± 0.025	1.462AlaMet: 1.462 ± 0.008	2.481AlaAsn: 2.481 ± 0.013	5.312AlaPro: 5.312 ± 0.022	2.327AlaGln: 2.327 ± 0.013	7.527AlaArg: 7.527 ± 0.1	6.013AlaSer: 6.013 ± 0.02	4.22AlaThr: 4.22 ± 0.019	5.237AlaVal: 5.237 ± 0.021	0.721AlaTrp: 0.721 ± 0.01	1.791AlaTyr: 1.791 ± 0.01	0.0AlaXaa: 0.0 ± 0.0
Cys	1.814CysAla: 1.814 ± 0.01	0.548CysCys: 0.548 ± 0.006	1.16CysAsp: 1.16 ± 0.011	1.223CysGlu: 1.223 ± 0.012	0.744CysPhe: 0.744 ± 0.006	1.632CysGly: 1.632 ± 0.012	0.578CysHis: 0.578 ± 0.007	1.025CysIle: 1.025 ± 0.011	0.982CysLys: 0.982 ± 0.008	1.808CysLeu: 1.808 ± 0.012	0.438CysMet: 0.438 ± 0.004	0.793CysAsn: 0.793 ± 0.006	1.248CysPro: 1.248 ± 0.011	0.668CysGln: 0.668 ± 0.006	1.895CysArg: 1.895 ± 0.012	1.823CysSer: 1.823 ± 0.01	1.268CysThr: 1.268 ± 0.008	1.529CysVal: 1.529 ± 0.01	0.241CysTrp: 0.241 ± 0.004	0.605CysTyr: 0.605 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	3.472AspAla: 3.472 ± 0.015	0.947AspCys: 0.947 ± 0.008	3.184AspAsp: 3.184 ± 0.016	3.299AspGlu: 3.299 ± 0.016	1.817AspPhe: 1.817 ± 0.011	3.029AspGly: 3.029 ± 0.016	1.163AspHis: 1.163 ± 0.009	2.956AspIle: 2.956 ± 0.014	2.405AspLys: 2.405 ± 0.013	4.056AspLeu: 4.056 ± 0.016	0.981AspMet: 0.981 ± 0.007	2.128AspAsn: 2.128 ± 0.015	2.265AspPro: 2.265 ± 0.014	1.3AspGln: 1.3 ± 0.008	3.453AspArg: 3.453 ± 0.015	3.862AspSer: 3.862 ± 0.018	2.653AspThr: 2.653 ± 0.013	3.37AspVal: 3.37 ± 0.015	0.544AspTrp: 0.544 ± 0.006	1.37AspTyr: 1.37 ± 0.009	0.0AspXaa: 0.0 ± 0.0
Glu	3.642GluAla: 3.642 ± 0.016	1.233GluCys: 1.233 ± 0.011	2.731GluAsp: 2.731 ± 0.014	4.055GluGlu: 4.055 ± 0.024	1.826GluPhe: 1.826 ± 0.01	2.827GluGly: 2.827 ± 0.015	1.332GluHis: 1.332 ± 0.008	3.476GluIle: 3.476 ± 0.018	3.577GluLys: 3.577 ± 0.019	4.942GluLeu: 4.942 ± 0.021	1.339GluMet: 1.339 ± 0.009	2.888GluAsn: 2.888 ± 0.015	2.422GluPro: 2.422 ± 0.013	1.996GluGln: 1.996 ± 0.012	4.796GluArg: 4.796 ± 0.018	4.171GluSer: 4.171 ± 0.018	3.378GluThr: 3.378 ± 0.018	3.194GluVal: 3.194 ± 0.014	0.801GluTrp: 0.801 ± 0.039	1.559GluTyr: 1.559 ± 0.01	0.0GluXaa: 0.0 ± 0.0
Phe	2.297PheAla: 2.297 ± 0.011	0.815PheCys: 0.815 ± 0.007	1.918PheAsp: 1.918 ± 0.012	1.867PheGlu: 1.867 ± 0.012	1.329PhePhe: 1.329 ± 0.01	2.104PheGly: 2.104 ± 0.012	0.915PheHis: 0.915 ± 0.007	1.815PheIle: 1.815 ± 0.009	1.818PheLys: 1.818 ± 0.011	3.048PheLeu: 3.048 ± 0.014	0.797PheMet: 0.797 ± 0.009	1.517PheAsn: 1.517 ± 0.009	1.632PhePro: 1.632 ± 0.011	1.153PheGln: 1.153 ± 0.009	2.449PheArg: 2.449 ± 0.012	2.707PheSer: 2.707 ± 0.012	2.001PheThr: 2.001 ± 0.011	2.255PheVal: 2.255 ± 0.012	0.419PheTrp: 0.419 ± 0.005	1.151PheTyr: 1.151 ± 0.008	0.0PheXaa: 0.0 ± 0.0
Gly	5.309GlyAla: 5.309 ± 0.057	1.305GlyCys: 1.305 ± 0.01	2.722GlyAsp: 2.722 ± 0.014	2.867GlyGlu: 2.867 ± 0.015	1.893GlyPhe: 1.893 ± 0.012	5.174GlyGly: 5.174 ± 0.031	1.634GlyHis: 1.634 ± 0.011	2.725GlyIle: 2.725 ± 0.015	2.749GlyLys: 2.749 ± 0.013	4.597GlyLeu: 4.597 ± 0.021	1.184GlyMet: 1.184 ± 0.037	2.05GlyAsn: 2.05 ± 0.011	3.222GlyPro: 3.222 ± 0.021	1.975GlyGln: 1.975 ± 0.099	6.095GlyArg: 6.095 ± 0.026	4.68GlySer: 4.68 ± 0.023	3.172GlyThr: 3.172 ± 0.018	3.887GlyVal: 3.887 ± 0.017	0.671GlyTrp: 0.671 ± 0.006	1.65GlyTyr: 1.65 ± 0.011	0.0GlyXaa: 0.0 ± 0.0
His	2.088HisAla: 2.088 ± 0.011	0.656HisCys: 0.656 ± 0.006	1.134HisAsp: 1.134 ± 0.007	1.295HisGlu: 1.295 ± 0.008	1.081HisPhe: 1.081 ± 0.008	1.5HisGly: 1.5 ± 0.01	0.916HisHis: 0.916 ± 0.012	1.368HisIle: 1.368 ± 0.009	1.269HisLys: 1.269 ± 0.008	2.439HisLeu: 2.439 ± 0.013	0.614HisMet: 0.614 ± 0.007	0.998HisAsn: 0.998 ± 0.011	1.516HisPro: 1.516 ± 0.01	0.987HisGln: 0.987 ± 0.008	2.393HisArg: 2.393 ± 0.014	2.162HisSer: 2.162 ± 0.011	1.653HisThr: 1.653 ± 0.012	1.67HisVal: 1.67 ± 0.011	0.332HisTrp: 0.332 ± 0.004	0.799HisTyr: 0.799 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	3.388IleAla: 3.388 ± 0.017	1.082IleCys: 1.082 ± 0.009	2.773IleAsp: 2.773 ± 0.017	3.297IleGlu: 3.297 ± 0.015	1.828IlePhe: 1.828 ± 0.011	2.705IleGly: 2.705 ± 0.012	1.276IleHis: 1.276 ± 0.008	2.783IleIle: 2.783 ± 0.017	3.231IleLys: 3.231 ± 0.015	4.283IleLeu: 4.283 ± 0.018	1.099IleMet: 1.099 ± 0.009	2.373IleAsn: 2.373 ± 0.012	2.527IlePro: 2.527 ± 0.014	1.77IleGln: 1.77 ± 0.01	3.644IleArg: 3.644 ± 0.015	4.105IleSer: 4.105 ± 0.016	3.09IleThr: 3.09 ± 0.022	3.098IleVal: 3.098 ± 0.015	0.487IleTrp: 0.487 ± 0.005	1.58IleTyr: 1.58 ± 0.009	0.0IleXaa: 0.0 ± 0.0
Lys	3.364LysAla: 3.364 ± 0.017	1.238LysCys: 1.238 ± 0.01	2.378LysAsp: 2.378 ± 0.015	3.327LysGlu: 3.327 ± 0.018	1.72LysPhe: 1.72 ± 0.01	2.485LysGly: 2.485 ± 0.013	1.274LysHis: 1.274 ± 0.013	3.279LysIle: 3.279 ± 0.015	4.154LysLys: 4.154 ± 0.026	4.839LysLeu: 4.839 ± 0.02	1.325LysMet: 1.325 ± 0.009	2.745LysAsn: 2.745 ± 0.013	2.63LysPro: 2.63 ± 0.021	2.042LysGln: 2.042 ± 0.011	4.283LysArg: 4.283 ± 0.017	4.17LysSer: 4.17 ± 0.019	3.44LysThr: 3.44 ± 0.017	2.972LysVal: 2.972 ± 0.014	0.706LysTrp: 0.706 ± 0.008	1.728LysTyr: 1.728 ± 0.011	0.0LysXaa: 0.0 ± 0.0
Leu	6.199LeuAla: 6.199 ± 0.023	1.922LeuCys: 1.922 ± 0.009	3.984LeuAsp: 3.984 ± 0.015	4.805LeuGlu: 4.805 ± 0.022	3.122LeuPhe: 3.122 ± 0.012	4.366LeuGly: 4.366 ± 0.018	2.534LeuHis: 2.534 ± 0.013	4.189LeuIle: 4.189 ± 0.018	5.222LeuLys: 5.222 ± 0.02	7.888LeuLeu: 7.888 ± 0.025	2.064LeuMet: 2.064 ± 0.009	3.648LeuAsn: 3.648 ± 0.015	4.915LeuPro: 4.915 ± 0.016	3.583LeuGln: 3.583 ± 0.017	7.121LeuArg: 7.121 ± 0.023	7.045LeuSer: 7.045 ± 0.023	5.092LeuThr: 5.092 ± 0.018	4.889LeuVal: 4.889 ± 0.02	1.039LeuTrp: 1.039 ± 0.009	2.493LeuTyr: 2.493 ± 0.013	0.0LeuXaa: 0.0 ± 0.0
Met	1.479MetAla: 1.479 ± 0.01	0.48MetCys: 0.48 ± 0.005	1.068MetAsp: 1.068 ± 0.008	1.415MetGlu: 1.415 ± 0.039	0.72MetPhe: 0.72 ± 0.007	1.135MetGly: 1.135 ± 0.011	0.558MetHis: 0.558 ± 0.006	1.056MetIle: 1.056 ± 0.007	1.414MetLys: 1.414 ± 0.009	1.808MetLeu: 1.808 ± 0.011	0.525MetMet: 0.525 ± 0.006	0.963MetAsn: 0.963 ± 0.007	1.064MetPro: 1.064 ± 0.008	0.798MetGln: 0.798 ± 0.006	1.712MetArg: 1.712 ± 0.009	1.856MetSer: 1.856 ± 0.01	1.313MetThr: 1.313 ± 0.008	1.197MetVal: 1.197 ± 0.008	0.236MetTrp: 0.236 ± 0.004	0.605MetTyr: 0.605 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.822AsnAla: 2.822 ± 0.013	0.868AsnCys: 0.868 ± 0.008	2.177AsnAsp: 2.177 ± 0.013	2.645AsnGlu: 2.645 ± 0.015	1.612AsnPhe: 1.612 ± 0.009	2.561AsnGly: 2.561 ± 0.04	0.954AsnHis: 0.954 ± 0.007	2.591AsnIle: 2.591 ± 0.013	2.678AsnLys: 2.678 ± 0.017	3.495AsnLeu: 3.495 ± 0.015	0.95AsnMet: 0.95 ± 0.007	2.121AsnAsn: 2.121 ± 0.014	1.844AsnPro: 1.844 ± 0.011	1.356AsnGln: 1.356 ± 0.012	2.79AsnArg: 2.79 ± 0.014	3.495AsnSer: 3.495 ± 0.016	2.367AsnThr: 2.367 ± 0.012	2.688AsnVal: 2.688 ± 0.013	0.455AsnTrp: 0.455 ± 0.005	1.347AsnTyr: 1.347 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	5.338ProAla: 5.338 ± 0.021	0.975ProCys: 0.975 ± 0.008	2.559ProAsp: 2.559 ± 0.013	2.862ProGlu: 2.862 ± 0.017	1.71ProPhe: 1.71 ± 0.01	3.296ProGly: 3.296 ± 0.097	1.645ProHis: 1.645 ± 0.011	2.478ProIle: 2.478 ± 0.013	2.57ProLys: 2.57 ± 0.017	4.763ProLeu: 4.763 ± 0.016	1.037ProMet: 1.037 ± 0.007	1.997ProAsn: 1.997 ± 0.015	5.497ProPro: 5.497 ± 0.026	1.918ProGln: 1.918 ± 0.013	5.11ProArg: 5.11 ± 0.022	4.956ProSer: 4.956 ± 0.02	3.601ProThr: 3.601 ± 0.02	3.391ProVal: 3.391 ± 0.017	0.562ProTrp: 0.562 ± 0.006	1.516ProTyr: 1.516 ± 0.012	0.0ProXaa: 0.0 ± 0.0
Gln	2.262GlnAla: 2.262 ± 0.101	0.809GlnCys: 0.809 ± 0.008	1.338GlnAsp: 1.338 ± 0.013	1.867GlnGlu: 1.867 ± 0.013	1.145GlnPhe: 1.145 ± 0.007	1.499GlnGly: 1.499 ± 0.01	1.002GlnHis: 1.002 ± 0.008	1.883GlnIle: 1.883 ± 0.011	2.056GlnLys: 2.056 ± 0.012	3.137GlnLeu: 3.137 ± 0.014	0.815GlnMet: 0.815 ± 0.006	1.77GlnAsn: 1.77 ± 0.012	1.879GlnPro: 1.879 ± 0.013	1.79GlnGln: 1.79 ± 0.019	3.073GlnArg: 3.073 ± 0.016	2.547GlnSer: 2.547 ± 0.013	2.168GlnThr: 2.168 ± 0.011	1.78GlnVal: 1.78 ± 0.01	0.475GlnTrp: 0.475 ± 0.005	1.026GlnTyr: 1.026 ± 0.008	0.0GlnXaa: 0.0 ± 0.0
Arg	7.56ArgAla: 7.56 ± 0.03	2.0ArgCys: 2.0 ± 0.011	3.67ArgAsp: 3.67 ± 0.017	4.066ArgGlu: 4.066 ± 0.017	2.599ArgPhe: 2.599 ± 0.015	5.37ArgGly: 5.37 ± 0.023	2.404ArgHis: 2.404 ± 0.014	3.602ArgIle: 3.602 ± 0.014	4.042ArgLys: 4.042 ± 0.019	7.026ArgLeu: 7.026 ± 0.026	1.658ArgMet: 1.658 ± 0.009	3.327ArgAsn: 3.327 ± 0.015	5.897ArgPro: 5.897 ± 0.098	2.697ArgGln: 2.697 ± 0.013	10.316ArgArg: 10.316 ± 0.042	6.897ArgSer: 6.897 ± 0.024	4.711ArgThr: 4.711 ± 0.02	4.962ArgVal: 4.962 ± 0.019	1.072ArgTrp: 1.072 ± 0.008	2.182ArgTyr: 2.182 ± 0.011	0.0ArgXaa: 0.0 ± 0.0
Ser	6.425SerAla: 6.425 ± 0.021	1.681SerCys: 1.681 ± 0.009	4.223SerAsp: 4.223 ± 0.014	4.557SerGlu: 4.557 ± 0.017	2.689SerPhe: 2.689 ± 0.012	5.271SerGly: 5.271 ± 0.023	2.149SerHis: 2.149 ± 0.012	3.903SerIle: 3.903 ± 0.019	4.056SerLys: 4.056 ± 0.018	6.662SerLeu: 6.662 ± 0.021	1.7SerMet: 1.7 ± 0.011	3.247SerAsn: 3.247 ± 0.016	4.962SerPro: 4.962 ± 0.019	2.615SerGln: 2.615 ± 0.018	6.681SerArg: 6.681 ± 0.025	7.86SerSer: 7.86 ± 0.033	5.085SerThr: 5.085 ± 0.022	5.072SerVal: 5.072 ± 0.016	0.834SerTrp: 0.834 ± 0.007	2.088SerTyr: 2.088 ± 0.011	0.0SerXaa: 0.0 ± 0.0
Thr	4.872ThrAla: 4.872 ± 0.02	1.285ThrCys: 1.285 ± 0.009	2.899ThrAsp: 2.899 ± 0.017	3.322ThrGlu: 3.322 ± 0.021	1.957ThrPhe: 1.957 ± 0.01	3.461ThrGly: 3.461 ± 0.016	1.638ThrHis: 1.638 ± 0.01	2.894ThrIle: 2.894 ± 0.014	3.156ThrLys: 3.156 ± 0.017	5.093ThrLeu: 5.093 ± 0.019	1.231ThrMet: 1.231 ± 0.008	2.425ThrAsn: 2.425 ± 0.013	3.715ThrPro: 3.715 ± 0.019	1.856ThrGln: 1.856 ± 0.011	4.55ThrArg: 4.55 ± 0.017	5.302ThrSer: 5.302 ± 0.022	3.945ThrThr: 3.945 ± 0.033	3.78ThrVal: 3.78 ± 0.015	0.641ThrTrp: 0.641 ± 0.006	1.666ThrTyr: 1.666 ± 0.01	0.0ThrXaa: 0.0 ± 0.0
Val	4.68ValAla: 4.68 ± 0.017	1.535ValCys: 1.535 ± 0.009	2.926ValAsp: 2.926 ± 0.013	3.444ValGlu: 3.444 ± 0.017	2.19ValPhe: 2.19 ± 0.012	3.401ValGly: 3.401 ± 0.016	1.673ValHis: 1.673 ± 0.011	3.094ValIle: 3.094 ± 0.014	3.304ValLys: 3.304 ± 0.015	5.388ValLeu: 5.388 ± 0.018	1.335ValMet: 1.335 ± 0.008	2.545ValAsn: 2.545 ± 0.012	3.271ValPro: 3.271 ± 0.016	2.168ValGln: 2.168 ± 0.013	4.787ValArg: 4.787 ± 0.02	4.915ValSer: 4.915 ± 0.019	4.232ValThr: 4.232 ± 0.018	4.141ValVal: 4.141 ± 0.019	0.711ValTrp: 0.711 ± 0.007	1.765ValTyr: 1.765 ± 0.01	0.0ValXaa: 0.0 ± 0.0
Trp	0.732TrpAla: 0.732 ± 0.007	0.272TrpCys: 0.272 ± 0.004	0.512TrpAsp: 0.512 ± 0.005	0.572TrpGlu: 0.572 ± 0.005	0.415TrpPhe: 0.415 ± 0.005	0.576TrpGly: 0.576 ± 0.006	0.288TrpHis: 0.288 ± 0.004	0.547TrpIle: 0.547 ± 0.005	0.724TrpLys: 0.724 ± 0.006	1.061TrpLeu: 1.061 ± 0.009	0.251TrpMet: 0.251 ± 0.003	0.578TrpAsn: 0.578 ± 0.038	0.656TrpPro: 0.656 ± 0.01	0.405TrpGln: 0.405 ± 0.005	1.155TrpArg: 1.155 ± 0.007	0.926TrpSer: 0.926 ± 0.007	0.696TrpThr: 0.696 ± 0.006	0.609TrpVal: 0.609 ± 0.006	0.199TrpTrp: 0.199 ± 0.004	0.316TrpTyr: 0.316 ± 0.004	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.932TyrAla: 1.932 ± 0.013	0.706TyrCys: 0.706 ± 0.006	1.46TyrAsp: 1.46 ± 0.008	1.569TyrGlu: 1.569 ± 0.009	1.211TyrPhe: 1.211 ± 0.009	1.703TyrGly: 1.703 ± 0.01	0.766TyrHis: 0.766 ± 0.007	1.437TyrIle: 1.437 ± 0.014	1.554TyrLys: 1.554 ± 0.01	2.626TyrLeu: 2.626 ± 0.011	0.597TyrMet: 0.597 ± 0.006	1.224TyrAsn: 1.224 ± 0.011	1.307TyrPro: 1.307 ± 0.009	0.917TyrGln: 0.917 ± 0.006	2.227TyrArg: 2.227 ± 0.011	2.269TyrSer: 2.269 ± 0.013	1.605TyrThr: 1.605 ± 0.011	1.783TyrVal: 1.783 ± 0.01	0.342TyrTrp: 0.342 ± 0.004	0.94TyrTyr: 0.94 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 96130 proteins (19894577 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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