Amino acid dipepetide frequency for Hubei odonate virus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.514AlaAla: 2.514 ± 0.672
1.257AlaCys: 1.257 ± 0.336
1.571AlaAsp: 1.571 ± 0.473
2.2AlaGlu: 2.2 ± 1.19
0.314AlaPhe: 0.314 ± 0.694
2.828AlaGly: 2.828 ± 0.429
1.571AlaHis: 1.571 ± 0.362
4.714AlaIle: 4.714 ± 0.375
1.571AlaLys: 1.571 ± 0.471
3.457AlaLeu: 3.457 ± 0.648
2.514AlaMet: 2.514 ± 0.893
3.143AlaAsn: 3.143 ± 0.724
1.886AlaPro: 1.886 ± 0.49
0.629AlaGln: 0.629 ± 0.34
1.257AlaArg: 1.257 ± 0.809
5.028AlaSer: 5.028 ± 3.299
2.828AlaThr: 2.828 ± 0.829
3.143AlaVal: 3.143 ± 3.138
0.0AlaTrp: 0.0 ± 0.0
2.2AlaTyr: 2.2 ± 0.786
0.0AlaXaa: 0.0 ± 0.0
Cys
0.629CysAla: 0.629 ± 0.255
0.314CysCys: 0.314 ± 0.17
1.886CysAsp: 1.886 ± 1.665
2.514CysGlu: 2.514 ± 0.144
0.629CysPhe: 0.629 ± 0.255
1.257CysGly: 1.257 ± 0.952
0.629CysHis: 0.629 ± 0.34
1.257CysIle: 1.257 ± 0.511
1.571CysLys: 1.571 ± 1.308
1.886CysLeu: 1.886 ± 1.02
0.314CysMet: 0.314 ± 0.17
1.257CysAsn: 1.257 ± 0.511
1.257CysPro: 1.257 ± 0.545
0.314CysGln: 0.314 ± 0.17
0.629CysArg: 0.629 ± 0.255
3.771CysSer: 3.771 ± 1.532
1.571CysThr: 1.571 ± 0.362
0.629CysVal: 0.629 ± 0.34
0.0CysTrp: 0.0 ± 0.0
0.943CysTyr: 0.943 ± 0.51
0.0CysXaa: 0.0 ± 0.0
Asp
0.943AspAla: 0.943 ± 0.51
0.943AspCys: 0.943 ± 0.51
4.4AspAsp: 4.4 ± 0.897
3.143AspGlu: 3.143 ± 1.7
3.143AspPhe: 3.143 ± 1.714
2.514AspGly: 2.514 ± 0.589
0.943AspHis: 0.943 ± 0.245
5.657AspIle: 5.657 ± 0.917
5.343AspLys: 5.343 ± 1.511
5.657AspLeu: 5.657 ± 1.6
0.629AspMet: 0.629 ± 0.255
5.028AspAsn: 5.028 ± 1.899
0.629AspPro: 0.629 ± 0.34
2.828AspGln: 2.828 ± 1.07
1.886AspArg: 1.886 ± 1.02
5.343AspSer: 5.343 ± 1.004
4.714AspThr: 4.714 ± 0.444
4.4AspVal: 4.4 ± 1.126
0.314AspTrp: 0.314 ± 0.17
2.514AspTyr: 2.514 ± 0.144
0.0AspXaa: 0.0 ± 0.0
Glu
3.457GluAla: 3.457 ± 0.174
1.571GluCys: 1.571 ± 0.473
4.714GluAsp: 4.714 ± 1.535
3.457GluGlu: 3.457 ± 0.872
2.2GluPhe: 2.2 ± 0.962
0.943GluGly: 0.943 ± 0.548
1.257GluHis: 1.257 ± 0.68
2.514GluIle: 2.514 ± 1.36
4.714GluLys: 4.714 ± 1.067
5.971GluLeu: 5.971 ± 0.764
1.257GluMet: 1.257 ± 0.336
2.828GluAsn: 2.828 ± 1.115
1.571GluPro: 1.571 ± 0.471
0.943GluGln: 0.943 ± 0.245
1.886GluArg: 1.886 ± 0.471
3.457GluSer: 3.457 ± 1.449
2.2GluThr: 2.2 ± 1.099
2.828GluVal: 2.828 ± 0.829
0.629GluTrp: 0.629 ± 0.34
2.828GluTyr: 2.828 ± 0.802
0.0GluXaa: 0.0 ± 0.0
Phe
2.2PheAla: 2.2 ± 1.896
1.571PheCys: 1.571 ± 0.85
2.2PheAsp: 2.2 ± 0.962
1.886PheGlu: 1.886 ± 0.766
0.314PhePhe: 0.314 ± 0.17
2.514PheGly: 2.514 ± 0.95
0.0PheHis: 0.0 ± 0.0
5.028PheIle: 5.028 ± 0.534
2.2PheLys: 2.2 ± 0.304
2.2PheLeu: 2.2 ± 0.795
0.943PheMet: 0.943 ± 0.598
2.828PheAsn: 2.828 ± 0.967
1.571PhePro: 1.571 ± 1.088
1.571PheGln: 1.571 ± 0.471
1.571PheArg: 1.571 ± 1.138
2.514PheSer: 2.514 ± 1.763
2.828PheThr: 2.828 ± 0.429
1.571PheVal: 1.571 ± 0.362
0.0PheTrp: 0.0 ± 0.0
0.629PheTyr: 0.629 ± 0.255
0.0PheXaa: 0.0 ± 0.0
Gly
1.886GlyAla: 1.886 ± 1.096
1.571GlyCys: 1.571 ± 1.308
2.514GlyAsp: 2.514 ± 0.672
1.571GlyGlu: 1.571 ± 0.473
1.257GlyPhe: 1.257 ± 0.476
1.571GlyGly: 1.571 ± 1.164
1.571GlyHis: 1.571 ± 0.64
3.457GlyIle: 3.457 ± 0.76
4.085GlyLys: 4.085 ± 0.621
4.4GlyLeu: 4.4 ± 1.572
1.886GlyMet: 1.886 ± 0.471
2.2GlyAsn: 2.2 ± 0.304
1.571GlyPro: 1.571 ± 0.362
1.886GlyGln: 1.886 ± 0.766
1.886GlyArg: 1.886 ± 0.626
4.714GlySer: 4.714 ± 1.226
2.2GlyThr: 2.2 ± 0.717
3.457GlyVal: 3.457 ± 0.648
1.257GlyTrp: 1.257 ± 0.511
2.514GlyTyr: 2.514 ± 0.706
0.0GlyXaa: 0.0 ± 0.0
His
1.571HisAla: 1.571 ± 0.471
0.314HisCys: 0.314 ± 0.358
1.571HisAsp: 1.571 ± 0.592
1.257HisGlu: 1.257 ± 0.336
0.629HisPhe: 0.629 ± 0.255
2.2HisGly: 2.2 ± 0.337
0.314HisHis: 0.314 ± 0.17
1.571HisIle: 1.571 ± 0.85
1.571HisLys: 1.571 ± 0.471
4.714HisLeu: 4.714 ± 1.228
0.0HisMet: 0.0 ± 0.0
1.571HisAsn: 1.571 ± 0.471
0.629HisPro: 0.629 ± 0.255
0.943HisGln: 0.943 ± 0.245
0.943HisArg: 0.943 ± 0.51
1.571HisSer: 1.571 ± 0.592
0.314HisThr: 0.314 ± 0.17
0.314HisVal: 0.314 ± 0.17
0.0HisTrp: 0.0 ± 0.0
1.886HisTyr: 1.886 ± 0.306
0.0HisXaa: 0.0 ± 0.0
Ile
2.514IleAla: 2.514 ± 0.927
2.2IleCys: 2.2 ± 0.304
5.657IleAsp: 5.657 ± 1.576
6.6IleGlu: 6.6 ± 0.185
2.2IlePhe: 2.2 ± 0.754
5.028IleGly: 5.028 ± 1.371
3.143IleHis: 3.143 ± 0.801
6.285IleIle: 6.285 ± 0.559
3.771IleLys: 3.771 ± 0.995
7.228IleLeu: 7.228 ± 1.706
1.571IleMet: 1.571 ± 0.473
4.714IleAsn: 4.714 ± 0.685
2.514IlePro: 2.514 ± 0.438
3.457IleGln: 3.457 ± 0.946
4.085IleArg: 4.085 ± 1.175
8.485IleSer: 8.485 ± 2.435
4.4IleThr: 4.4 ± 1.187
2.828IleVal: 2.828 ± 0.802
0.0IleTrp: 0.0 ± 0.0
4.085IleTyr: 4.085 ± 0.728
0.0IleXaa: 0.0 ± 0.0
Lys
3.457LysAla: 3.457 ± 1.096
0.943LysCys: 0.943 ± 0.245
5.028LysAsp: 5.028 ± 0.288
3.771LysGlu: 3.771 ± 0.612
4.085LysPhe: 4.085 ± 0.621
2.828LysGly: 2.828 ± 0.083
2.514LysHis: 2.514 ± 0.672
5.343LysIle: 5.343 ± 2.008
2.828LysLys: 2.828 ± 0.572
6.6LysLeu: 6.6 ± 0.994
3.143LysMet: 3.143 ± 1.843
4.4LysAsn: 4.4 ± 1.126
2.2LysPro: 2.2 ± 0.795
1.886LysGln: 1.886 ± 1.054
3.143LysArg: 3.143 ± 0.225
3.457LysSer: 3.457 ± 1.131
3.771LysThr: 3.771 ± 1.04
6.285LysVal: 6.285 ± 0.884
0.0LysTrp: 0.0 ± 0.0
6.6LysTyr: 6.6 ± 0.994
0.0LysXaa: 0.0 ± 0.0
Leu
5.971LeuAla: 5.971 ± 3.052
0.943LeuCys: 0.943 ± 0.51
5.028LeuAsp: 5.028 ± 1.149
2.514LeuGlu: 2.514 ± 1.36
3.771LeuPhe: 3.771 ± 1.008
4.085LeuGly: 4.085 ± 1.042
0.943LeuHis: 0.943 ± 0.51
5.971LeuIle: 5.971 ± 1.701
7.228LeuLys: 7.228 ± 3.066
9.742LeuLeu: 9.742 ± 1.13
1.886LeuMet: 1.886 ± 0.471
6.285LeuAsn: 6.285 ± 0.946
2.514LeuPro: 2.514 ± 1.36
1.257LeuGln: 1.257 ± 0.68
5.028LeuArg: 5.028 ± 0.534
8.171LeuSer: 8.171 ± 0.58
6.285LeuThr: 6.285 ± 0.951
5.971LeuVal: 5.971 ± 0.764
0.943LeuTrp: 0.943 ± 0.245
3.143LeuTyr: 3.143 ± 0.942
0.0LeuXaa: 0.0 ± 0.0
Met
1.571MetAla: 1.571 ± 1.088
0.314MetCys: 0.314 ± 0.17
1.886MetAsp: 1.886 ± 1.02
1.257MetGlu: 1.257 ± 0.511
0.0MetPhe: 0.0 ± 0.0
1.571MetGly: 1.571 ± 0.473
1.257MetHis: 1.257 ± 0.511
1.886MetIle: 1.886 ± 0.471
2.2MetLys: 2.2 ± 1.896
3.143MetLeu: 3.143 ± 0.945
0.943MetMet: 0.943 ± 0.245
1.257MetAsn: 1.257 ± 0.476
2.2MetPro: 2.2 ± 2.705
0.943MetGln: 0.943 ± 0.51
1.571MetArg: 1.571 ± 0.85
2.514MetSer: 2.514 ± 0.438
1.886MetThr: 1.886 ± 0.626
0.629MetVal: 0.629 ± 0.602
0.0MetTrp: 0.0 ± 0.0
1.571MetTyr: 1.571 ± 1.308
0.0MetXaa: 0.0 ± 0.0
Asn
2.828AsnAla: 2.828 ± 0.829
2.2AsnCys: 2.2 ± 1.099
4.4AsnAsp: 4.4 ± 1.273
3.143AsnGlu: 3.143 ± 0.225
2.828AsnPhe: 2.828 ± 0.802
3.771AsnGly: 3.771 ± 0.981
0.629AsnHis: 0.629 ± 0.34
4.714AsnIle: 4.714 ± 1.228
6.6AsnLys: 6.6 ± 1.269
5.971AsnLeu: 5.971 ± 0.919
2.514AsnMet: 2.514 ± 0.144
4.714AsnAsn: 4.714 ± 1.228
2.2AsnPro: 2.2 ± 0.304
1.257AsnGln: 1.257 ± 0.336
2.828AsnArg: 2.828 ± 1.07
4.085AsnSer: 4.085 ± 0.494
3.457AsnThr: 3.457 ± 1.606
5.657AsnVal: 5.657 ± 0.858
0.629AsnTrp: 0.629 ± 0.34
3.457AsnTyr: 3.457 ± 1.449
0.0AsnXaa: 0.0 ± 0.0
Pro
1.571ProAla: 1.571 ± 2.176
0.0ProCys: 0.0 ± 0.0
2.514ProAsp: 2.514 ± 0.952
1.571ProGlu: 1.571 ± 0.85
1.886ProPhe: 1.886 ± 0.49
0.629ProGly: 0.629 ± 0.255
0.943ProHis: 0.943 ± 0.245
2.828ProIle: 2.828 ± 0.967
4.714ProLys: 4.714 ± 1.087
2.514ProLeu: 2.514 ± 1.65
1.571ProMet: 1.571 ± 0.471
1.571ProAsn: 1.571 ± 0.473
2.2ProPro: 2.2 ± 0.754
1.257ProGln: 1.257 ± 0.336
0.0ProArg: 0.0 ± 0.0
3.143ProSer: 3.143 ± 1.492
3.771ProThr: 3.771 ± 2.466
1.886ProVal: 1.886 ± 0.306
0.0ProTrp: 0.0 ± 0.0
1.886ProTyr: 1.886 ± 1.054
0.0ProXaa: 0.0 ± 0.0
Gln
1.886GlnAla: 1.886 ± 0.471
0.629GlnCys: 0.629 ± 0.716
0.943GlnAsp: 0.943 ± 0.245
0.629GlnGlu: 0.629 ± 0.255
0.943GlnPhe: 0.943 ± 0.51
1.886GlnGly: 1.886 ± 0.626
0.314GlnHis: 0.314 ± 0.358
3.143GlnIle: 3.143 ± 1.282
0.629GlnLys: 0.629 ± 0.34
2.514GlnLeu: 2.514 ± 0.95
1.571GlnMet: 1.571 ± 0.592
2.2GlnAsn: 2.2 ± 0.717
0.629GlnPro: 0.629 ± 0.34
1.571GlnGln: 1.571 ± 0.85
1.886GlnArg: 1.886 ± 0.471
4.085GlnSer: 4.085 ± 0.728
1.571GlnThr: 1.571 ± 1.383
1.257GlnVal: 1.257 ± 0.68
0.314GlnTrp: 0.314 ± 0.17
2.828GlnTyr: 2.828 ± 0.572
0.0GlnXaa: 0.0 ± 0.0
Arg
0.943ArgAla: 0.943 ± 0.245
0.943ArgCys: 0.943 ± 0.598
1.257ArgAsp: 1.257 ± 0.476
2.828ArgGlu: 2.828 ± 0.802
1.886ArgPhe: 1.886 ± 0.306
1.886ArgGly: 1.886 ± 0.626
1.257ArgHis: 1.257 ± 0.336
2.514ArgIle: 2.514 ± 0.438
3.771ArgLys: 3.771 ± 1.185
5.343ArgLeu: 5.343 ± 0.978
0.943ArgMet: 0.943 ± 0.548
4.714ArgAsn: 4.714 ± 2.018
1.886ArgPro: 1.886 ± 0.471
2.828ArgGln: 2.828 ± 0.572
3.457ArgArg: 3.457 ± 0.174
2.2ArgSer: 2.2 ± 1.748
2.514ArgThr: 2.514 ± 1.23
2.2ArgVal: 2.2 ± 1.19
0.314ArgTrp: 0.314 ± 0.17
2.2ArgTyr: 2.2 ± 0.563
0.0ArgXaa: 0.0 ± 0.0
Ser
3.771SerAla: 3.771 ± 1.324
2.2SerCys: 2.2 ± 1.099
3.771SerAsp: 3.771 ± 0.559
4.4SerGlu: 4.4 ± 0.765
4.085SerPhe: 4.085 ± 0.871
4.714SerGly: 4.714 ± 1.087
2.514SerHis: 2.514 ± 0.893
8.799SerIle: 8.799 ± 0.368
8.171SerLys: 8.171 ± 1.005
5.657SerLeu: 5.657 ± 0.917
3.143SerMet: 3.143 ± 0.28
5.028SerAsn: 5.028 ± 0.811
1.886SerPro: 1.886 ± 1.557
2.514SerGln: 2.514 ± 0.927
4.4SerArg: 4.4 ± 1.389
6.6SerSer: 6.6 ± 2.0
4.085SerThr: 4.085 ± 1.527
5.343SerVal: 5.343 ± 1.738
1.257SerTrp: 1.257 ± 0.511
4.4SerTyr: 4.4 ± 1.188
0.0SerXaa: 0.0 ± 0.0
Thr
1.257ThrAla: 1.257 ± 0.68
2.2ThrCys: 2.2 ± 0.563
2.514ThrAsp: 2.514 ± 0.893
2.2ThrGlu: 2.2 ± 0.563
2.828ThrPhe: 2.828 ± 2.92
1.257ThrGly: 1.257 ± 0.809
0.943ThrHis: 0.943 ± 0.51
5.971ThrIle: 5.971 ± 0.704
5.028ThrLys: 5.028 ± 1.236
4.714ThrLeu: 4.714 ± 0.444
1.257ThrMet: 1.257 ± 0.613
5.028ThrAsn: 5.028 ± 1.016
4.714ThrPro: 4.714 ± 3.493
1.257ThrGln: 1.257 ± 0.476
1.886ThrArg: 1.886 ± 0.306
6.914ThrSer: 6.914 ± 2.221
5.028ThrThr: 5.028 ± 1.094
2.514ThrVal: 2.514 ± 1.021
0.629ThrTrp: 0.629 ± 0.716
1.257ThrTyr: 1.257 ± 0.476
0.0ThrXaa: 0.0 ± 0.0
Val
3.457ValAla: 3.457 ± 0.872
1.571ValCys: 1.571 ± 1.164
5.657ValAsp: 5.657 ± 0.801
3.143ValGlu: 3.143 ± 1.282
2.514ValPhe: 2.514 ± 0.927
1.257ValGly: 1.257 ± 1.257
1.886ValHis: 1.886 ± 0.626
3.771ValIle: 3.771 ± 0.612
3.143ValLys: 3.143 ± 1.279
2.514ValLeu: 2.514 ± 0.672
0.629ValMet: 0.629 ± 0.34
4.714ValAsn: 4.714 ± 0.867
1.886ValPro: 1.886 ± 0.921
2.514ValGln: 2.514 ± 0.589
2.828ValArg: 2.828 ± 0.735
5.657ValSer: 5.657 ± 0.801
3.771ValThr: 3.771 ± 1.401
4.085ValVal: 4.085 ± 1.861
1.257ValTrp: 1.257 ± 0.68
1.886ValTyr: 1.886 ± 1.404
0.0ValXaa: 0.0 ± 0.0
Trp
0.629TrpAla: 0.629 ± 0.34
0.943TrpCys: 0.943 ± 0.598
0.629TrpAsp: 0.629 ± 0.34
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.629TrpGly: 0.629 ± 0.34
0.0TrpHis: 0.0 ± 0.0
0.629TrpIle: 0.629 ± 0.34
0.0TrpLys: 0.0 ± 0.0
0.629TrpLeu: 0.629 ± 0.255
0.314TrpMet: 0.314 ± 0.17
0.314TrpAsn: 0.314 ± 0.17
0.629TrpPro: 0.629 ± 0.34
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
0.629TrpSer: 0.629 ± 0.255
0.629TrpThr: 0.629 ± 0.255
0.314TrpVal: 0.314 ± 0.17
0.0TrpTrp: 0.0 ± 0.0
0.943TrpTyr: 0.943 ± 0.598
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.571TyrAla: 1.571 ± 0.471
0.629TyrCys: 0.629 ± 0.255
2.828TyrAsp: 2.828 ± 0.735
3.143TyrGlu: 3.143 ± 1.623
0.629TyrPhe: 0.629 ± 0.34
4.085TyrGly: 4.085 ± 1.135
1.257TyrHis: 1.257 ± 0.336
4.714TyrIle: 4.714 ± 0.685
3.143TyrLys: 3.143 ± 0.225
2.828TyrLeu: 2.828 ± 0.802
1.257TyrMet: 1.257 ± 0.68
4.085TyrAsn: 4.085 ± 0.494
1.886TyrPro: 1.886 ± 0.471
1.571TyrGln: 1.571 ± 0.473
4.714TyrArg: 4.714 ± 0.646
4.4TyrSer: 4.4 ± 1.126
1.886TyrThr: 1.886 ± 1.665
2.828TyrVal: 2.828 ± 1.352
0.314TyrTrp: 0.314 ± 0.17
1.571TyrTyr: 1.571 ± 0.473
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3183 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski