Amino acid dipepetide frequency for Sugarcane striate mosaic-associated virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.969AlaAla: 1.969 ± 2.654
1.969AlaCys: 1.969 ± 0.71
0.394AlaAsp: 0.394 ± 0.198
4.332AlaGlu: 4.332 ± 1.244
4.726AlaPhe: 4.726 ± 1.632
3.151AlaGly: 3.151 ± 0.741
1.182AlaHis: 1.182 ± 1.245
6.302AlaIle: 6.302 ± 1.478
5.12AlaLys: 5.12 ± 1.226
4.726AlaLeu: 4.726 ± 5.471
0.788AlaMet: 0.788 ± 0.743
4.332AlaAsn: 4.332 ± 1.589
2.757AlaPro: 2.757 ± 0.962
1.575AlaGln: 1.575 ± 0.693
3.545AlaArg: 3.545 ± 1.429
3.939AlaSer: 3.939 ± 2.13
1.575AlaThr: 1.575 ± 0.791
2.363AlaVal: 2.363 ± 0.845
1.182AlaTrp: 1.182 ± 0.69
2.363AlaTyr: 2.363 ± 0.849
0.0AlaXaa: 0.0 ± 0.0
Cys
3.939CysAla: 3.939 ± 1.463
0.788CysCys: 0.788 ± 0.396
1.969CysAsp: 1.969 ± 0.749
0.788CysGlu: 0.788 ± 0.873
2.363CysPhe: 2.363 ± 1.187
1.575CysGly: 1.575 ± 0.989
0.394CysHis: 0.394 ± 0.198
2.757CysIle: 2.757 ± 1.876
0.788CysLys: 0.788 ± 0.396
1.182CysLeu: 1.182 ± 0.593
0.394CysMet: 0.394 ± 0.198
0.0CysAsn: 0.0 ± 0.0
0.788CysPro: 0.788 ± 0.396
0.394CysGln: 0.394 ± 1.153
1.182CysArg: 1.182 ± 1.482
1.969CysSer: 1.969 ± 0.989
1.969CysThr: 1.969 ± 1.864
1.575CysVal: 1.575 ± 0.715
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.182AspAla: 1.182 ± 0.593
1.575AspCys: 1.575 ± 0.791
2.363AspAsp: 2.363 ± 0.758
3.545AspGlu: 3.545 ± 0.763
4.332AspPhe: 4.332 ± 0.942
3.545AspGly: 3.545 ± 1.842
1.969AspHis: 1.969 ± 0.989
4.332AspIle: 4.332 ± 1.244
3.151AspLys: 3.151 ± 1.385
6.302AspLeu: 6.302 ± 1.05
1.182AspMet: 1.182 ± 0.593
2.363AspAsn: 2.363 ± 1.983
2.757AspPro: 2.757 ± 0.85
3.545AspGln: 3.545 ± 1.756
1.575AspArg: 1.575 ± 0.791
3.545AspSer: 3.545 ± 1.292
1.182AspThr: 1.182 ± 1.73
1.575AspVal: 1.575 ± 0.791
0.394AspTrp: 0.394 ± 0.198
2.363AspTyr: 2.363 ± 1.187
0.0AspXaa: 0.0 ± 0.0
Glu
4.332GluAla: 4.332 ± 2.176
2.757GluCys: 2.757 ± 0.85
3.151GluAsp: 3.151 ± 1.129
3.151GluGlu: 3.151 ± 1.129
1.969GluPhe: 1.969 ± 0.989
1.575GluGly: 1.575 ± 1.092
0.788GluHis: 0.788 ± 0.396
5.514GluIle: 5.514 ± 2.23
4.726GluLys: 4.726 ± 1.075
5.908GluLeu: 5.908 ± 1.56
0.394GluMet: 0.394 ± 0.807
3.151GluAsn: 3.151 ± 0.974
3.151GluPro: 3.151 ± 1.385
2.363GluGln: 2.363 ± 1.651
4.332GluArg: 4.332 ± 1.315
6.696GluSer: 6.696 ± 1.774
1.969GluThr: 1.969 ± 1.42
3.545GluVal: 3.545 ± 1.429
0.0GluTrp: 0.0 ± 0.0
1.182GluTyr: 1.182 ± 0.773
0.0GluXaa: 0.0 ± 0.0
Phe
3.151PheAla: 3.151 ± 0.963
2.363PheCys: 2.363 ± 1.381
3.545PheAsp: 3.545 ± 1.292
4.726PheGlu: 4.726 ± 1.28
3.151PhePhe: 3.151 ± 0.963
3.151PheGly: 3.151 ± 1.737
1.575PheHis: 1.575 ± 0.791
3.545PheIle: 3.545 ± 1.552
5.514PheLys: 5.514 ± 1.545
5.908PheLeu: 5.908 ± 2.447
0.788PheMet: 0.788 ± 0.396
1.575PheAsn: 1.575 ± 0.791
2.363PhePro: 2.363 ± 0.758
1.969PheGln: 1.969 ± 0.71
2.363PheArg: 2.363 ± 1.758
3.939PheSer: 3.939 ± 1.914
2.363PheThr: 2.363 ± 1.187
5.12PheVal: 5.12 ± 1.847
0.788PheTrp: 0.788 ± 1.064
1.969PheTyr: 1.969 ± 0.749
0.0PheXaa: 0.0 ± 0.0
Gly
2.363GlyAla: 2.363 ± 1.381
1.575GlyCys: 1.575 ± 1.879
4.726GlyAsp: 4.726 ± 1.866
3.545GlyGlu: 3.545 ± 1.12
1.182GlyPhe: 1.182 ± 0.593
1.182GlyGly: 1.182 ± 2.473
1.969GlyHis: 1.969 ± 2.064
3.151GlyIle: 3.151 ± 1.582
5.12GlyLys: 5.12 ± 1.276
5.12GlyLeu: 5.12 ± 1.226
0.788GlyMet: 0.788 ± 0.396
1.575GlyAsn: 1.575 ± 1.341
0.788GlyPro: 0.788 ± 0.743
1.969GlyGln: 1.969 ± 0.989
2.757GlyArg: 2.757 ± 0.85
4.726GlySer: 4.726 ± 1.075
1.969GlyThr: 1.969 ± 2.443
1.969GlyVal: 1.969 ± 1.562
0.788GlyTrp: 0.788 ± 1.803
2.363GlyTyr: 2.363 ± 0.845
0.0GlyXaa: 0.0 ± 0.0
His
0.394HisAla: 0.394 ± 1.002
0.394HisCys: 0.394 ± 0.198
1.182HisAsp: 1.182 ± 0.593
1.969HisGlu: 1.969 ± 0.749
2.363HisPhe: 2.363 ± 2.016
0.394HisGly: 0.394 ± 0.198
1.969HisHis: 1.969 ± 0.989
1.969HisIle: 1.969 ± 1.864
0.788HisLys: 0.788 ± 0.396
5.12HisLeu: 5.12 ± 1.611
0.788HisMet: 0.788 ± 0.396
1.575HisAsn: 1.575 ± 0.791
0.394HisPro: 0.394 ± 0.198
0.0HisGln: 0.0 ± 0.0
0.788HisArg: 0.788 ± 0.873
2.757HisSer: 2.757 ± 0.85
1.182HisThr: 1.182 ± 1.301
1.575HisVal: 1.575 ± 0.791
0.394HisTrp: 0.394 ± 1.153
2.757HisTyr: 2.757 ± 1.035
0.0HisXaa: 0.0 ± 0.0
Ile
4.332IleAla: 4.332 ± 3.423
1.575IleCys: 1.575 ± 0.989
3.545IleAsp: 3.545 ± 1.552
3.545IleGlu: 3.545 ± 1.292
2.363IlePhe: 2.363 ± 0.845
5.514IleGly: 5.514 ± 1.7
1.182IleHis: 1.182 ± 1.73
2.757IleIle: 2.757 ± 2.341
8.271IleLys: 8.271 ± 1.063
9.453IleLeu: 9.453 ± 1.76
1.969IleMet: 1.969 ± 0.989
4.726IleAsn: 4.726 ± 1.075
2.757IlePro: 2.757 ± 1.035
1.969IleGln: 1.969 ± 0.989
2.363IleArg: 2.363 ± 0.845
4.332IleSer: 4.332 ± 1.449
3.151IleThr: 3.151 ± 3.598
1.969IleVal: 1.969 ± 1.637
0.788IleTrp: 0.788 ± 1.064
1.575IleTyr: 1.575 ± 1.984
0.0IleXaa: 0.0 ± 0.0
Lys
4.726LysAla: 4.726 ± 1.654
1.182LysCys: 1.182 ± 0.773
3.939LysAsp: 3.939 ± 1.545
5.12LysGlu: 5.12 ± 2.735
6.302LysPhe: 6.302 ± 2.08
4.332LysGly: 4.332 ± 0.942
1.575LysHis: 1.575 ± 1.677
3.939LysIle: 3.939 ± 1.351
4.726LysLys: 4.726 ± 1.823
6.302LysLeu: 6.302 ± 2.363
2.363LysMet: 2.363 ± 1.187
5.514LysAsn: 5.514 ± 2.769
1.969LysPro: 1.969 ± 0.71
2.757LysGln: 2.757 ± 1.626
2.363LysArg: 2.363 ± 1.187
7.089LysSer: 7.089 ± 2.038
3.939LysThr: 3.939 ± 1.28
3.939LysVal: 3.939 ± 1.464
0.394LysTrp: 0.394 ± 1.894
2.757LysTyr: 2.757 ± 0.77
0.0LysXaa: 0.0 ± 0.0
Leu
7.483LeuAla: 7.483 ± 1.532
1.575LeuCys: 1.575 ± 0.989
3.939LeuAsp: 3.939 ± 1.503
7.483LeuGlu: 7.483 ± 1.437
6.302LeuPhe: 6.302 ± 1.735
3.545LeuGly: 3.545 ± 1.885
3.545LeuHis: 3.545 ± 1.627
7.089LeuIle: 7.089 ± 1.737
7.877LeuLys: 7.877 ± 3.956
11.028LeuLeu: 11.028 ± 6.409
3.545LeuMet: 3.545 ± 1.399
5.908LeuAsn: 5.908 ± 1.56
3.151LeuPro: 3.151 ± 0.992
1.969LeuGln: 1.969 ± 0.71
5.12LeuArg: 5.12 ± 2.015
7.877LeuSer: 7.877 ± 3.528
5.514LeuThr: 5.514 ± 3.111
6.302LeuVal: 6.302 ± 2.262
0.788LeuTrp: 0.788 ± 0.396
3.939LeuTyr: 3.939 ± 1.545
0.0LeuXaa: 0.0 ± 0.0
Met
1.969MetAla: 1.969 ± 0.749
0.0MetCys: 0.0 ± 0.0
1.182MetAsp: 1.182 ± 0.593
1.575MetGlu: 1.575 ± 0.715
0.788MetPhe: 0.788 ± 0.396
1.575MetGly: 1.575 ± 0.791
0.788MetHis: 0.788 ± 0.743
2.363MetIle: 2.363 ± 1.187
1.969MetLys: 1.969 ± 1.008
1.969MetLeu: 1.969 ± 0.989
0.394MetMet: 0.394 ± 0.198
0.788MetAsn: 0.788 ± 0.396
1.182MetPro: 1.182 ± 0.593
0.788MetGln: 0.788 ± 1.803
1.575MetArg: 1.575 ± 0.693
1.182MetSer: 1.182 ± 1.301
0.788MetThr: 0.788 ± 0.396
1.182MetVal: 1.182 ± 0.593
0.0MetTrp: 0.0 ± 0.0
0.394MetTyr: 0.394 ± 0.198
0.0MetXaa: 0.0 ± 0.0
Asn
2.757AsnAla: 2.757 ± 1.369
1.575AsnCys: 1.575 ± 0.715
2.757AsnAsp: 2.757 ± 1.384
3.545AsnGlu: 3.545 ± 1.292
2.363AsnPhe: 2.363 ± 1.187
2.757AsnGly: 2.757 ± 1.384
1.575AsnHis: 1.575 ± 0.791
2.363AsnIle: 2.363 ± 1.065
1.969AsnLys: 1.969 ± 1.074
5.514AsnLeu: 5.514 ± 1.7
1.969AsnMet: 1.969 ± 0.749
1.969AsnAsn: 1.969 ± 1.008
1.969AsnPro: 1.969 ± 1.215
1.182AsnGln: 1.182 ± 1.73
1.575AsnArg: 1.575 ± 1.092
3.939AsnSer: 3.939 ± 2.016
2.363AsnThr: 2.363 ± 1.111
3.151AsnVal: 3.151 ± 1.129
0.788AsnTrp: 0.788 ± 0.743
1.182AsnTyr: 1.182 ± 0.593
0.0AsnXaa: 0.0 ± 0.0
Pro
2.757ProAla: 2.757 ± 0.979
1.182ProCys: 1.182 ± 0.593
2.363ProAsp: 2.363 ± 1.758
2.363ProGlu: 2.363 ± 0.849
1.575ProPhe: 1.575 ± 2.507
1.182ProGly: 1.182 ± 0.773
1.182ProHis: 1.182 ± 0.773
2.757ProIle: 2.757 ± 0.85
1.969ProLys: 1.969 ± 1.008
3.151ProLeu: 3.151 ± 3.138
0.394ProMet: 0.394 ± 0.198
1.969ProAsn: 1.969 ± 1.215
3.545ProPro: 3.545 ± 2.176
0.788ProGln: 0.788 ± 0.396
1.969ProArg: 1.969 ± 1.008
3.939ProSer: 3.939 ± 1.463
1.182ProThr: 1.182 ± 1.573
2.757ProVal: 2.757 ± 0.85
1.182ProTrp: 1.182 ± 0.773
1.575ProTyr: 1.575 ± 0.791
0.0ProXaa: 0.0 ± 0.0
Gln
1.575GlnAla: 1.575 ± 1.677
0.394GlnCys: 0.394 ± 1.894
1.182GlnAsp: 1.182 ± 0.593
3.151GlnGlu: 3.151 ± 1.583
0.788GlnPhe: 0.788 ± 0.396
1.969GlnGly: 1.969 ± 0.989
0.394GlnHis: 0.394 ± 0.198
2.363GlnIle: 2.363 ± 1.187
1.969GlnLys: 1.969 ± 1.777
3.545GlnLeu: 3.545 ± 1.78
0.394GlnMet: 0.394 ± 0.376
2.363GlnAsn: 2.363 ± 0.845
1.969GlnPro: 1.969 ± 2.224
0.788GlnGln: 0.788 ± 2.124
0.788GlnArg: 0.788 ± 1.803
1.969GlnSer: 1.969 ± 0.989
0.788GlnThr: 0.788 ± 0.396
1.969GlnVal: 1.969 ± 1.979
0.0GlnTrp: 0.0 ± 0.0
0.394GlnTyr: 0.394 ± 1.002
0.0GlnXaa: 0.0 ± 0.0
Arg
2.363ArgAla: 2.363 ± 0.849
0.394ArgCys: 0.394 ± 0.198
1.182ArgAsp: 1.182 ± 0.69
1.969ArgGlu: 1.969 ± 0.989
4.726ArgPhe: 4.726 ± 1.28
1.575ArgGly: 1.575 ± 0.693
0.788ArgHis: 0.788 ± 0.396
1.969ArgIle: 1.969 ± 0.989
2.757ArgLys: 2.757 ± 0.77
3.545ArgLeu: 3.545 ± 1.12
2.757ArgMet: 2.757 ± 1.628
2.363ArgAsn: 2.363 ± 0.849
0.788ArgPro: 0.788 ± 1.803
0.394ArgGln: 0.394 ± 1.153
4.332ArgArg: 4.332 ± 3.904
6.302ArgSer: 6.302 ± 1.361
1.182ArgThr: 1.182 ± 3.006
2.757ArgVal: 2.757 ± 1.222
0.788ArgTrp: 0.788 ± 0.396
2.363ArgTyr: 2.363 ± 1.111
0.0ArgXaa: 0.0 ± 0.0
Ser
5.12SerAla: 5.12 ± 1.757
1.969SerCys: 1.969 ± 0.749
5.12SerAsp: 5.12 ± 0.727
2.757SerGlu: 2.757 ± 1.153
4.332SerPhe: 4.332 ± 1.641
5.514SerGly: 5.514 ± 1.782
2.363SerHis: 2.363 ± 0.758
5.12SerIle: 5.12 ± 1.315
6.302SerLys: 6.302 ± 2.335
9.453SerLeu: 9.453 ± 3.472
0.788SerMet: 0.788 ± 0.743
2.757SerAsn: 2.757 ± 2.023
3.545SerPro: 3.545 ± 0.926
2.363SerGln: 2.363 ± 1.639
3.151SerArg: 3.151 ± 1.129
9.059SerSer: 9.059 ± 2.41
5.12SerThr: 5.12 ± 1.901
3.939SerVal: 3.939 ± 1.978
0.788SerTrp: 0.788 ± 0.396
5.514SerTyr: 5.514 ± 2.123
0.0SerXaa: 0.0 ± 0.0
Thr
2.757ThrAla: 2.757 ± 3.781
0.788ThrCys: 0.788 ± 0.396
1.575ThrAsp: 1.575 ± 1.879
3.151ThrGlu: 3.151 ± 1.421
5.908ThrPhe: 5.908 ± 2.175
2.757ThrGly: 2.757 ± 1.876
2.363ThrHis: 2.363 ± 2.016
1.969ThrIle: 1.969 ± 1.562
2.757ThrLys: 2.757 ± 2.475
4.332ThrLeu: 4.332 ± 2.286
0.788ThrMet: 0.788 ± 0.396
0.788ThrAsn: 0.788 ± 0.396
2.363ThrPro: 2.363 ± 1.065
0.788ThrGln: 0.788 ± 0.743
1.969ThrArg: 1.969 ± 0.71
5.12ThrSer: 5.12 ± 4.111
1.969ThrThr: 1.969 ± 1.42
1.969ThrVal: 1.969 ± 0.749
0.0ThrTrp: 0.0 ± 0.0
1.575ThrTyr: 1.575 ± 0.715
0.0ThrXaa: 0.0 ± 0.0
Val
1.969ValAla: 1.969 ± 0.956
1.182ValCys: 1.182 ± 1.482
5.12ValAsp: 5.12 ± 2.007
2.363ValGlu: 2.363 ± 0.849
1.969ValPhe: 1.969 ± 1.777
1.969ValGly: 1.969 ± 0.989
1.575ValHis: 1.575 ± 0.715
1.969ValIle: 1.969 ± 1.637
5.908ValLys: 5.908 ± 2.383
4.332ValLeu: 4.332 ± 2.187
1.182ValMet: 1.182 ± 0.593
1.575ValAsn: 1.575 ± 0.791
2.363ValPro: 2.363 ± 1.832
3.151ValGln: 3.151 ± 0.974
2.363ValArg: 2.363 ± 1.0
5.12ValSer: 5.12 ± 1.822
4.332ValThr: 4.332 ± 1.323
4.332ValVal: 4.332 ± 2.019
1.182ValTrp: 1.182 ± 0.69
1.575ValTyr: 1.575 ± 0.989
0.0ValXaa: 0.0 ± 0.0
Trp
1.182TrpAla: 1.182 ± 0.69
0.394TrpCys: 0.394 ± 1.153
0.394TrpAsp: 0.394 ± 0.198
0.0TrpGlu: 0.0 ± 0.0
0.394TrpPhe: 0.394 ± 1.894
0.0TrpGly: 0.0 ± 0.0
0.788TrpHis: 0.788 ± 0.396
0.0TrpIle: 0.0 ± 0.0
0.394TrpLys: 0.394 ± 0.198
3.545TrpLeu: 3.545 ± 2.716
0.0TrpMet: 0.0 ± 0.0
0.394TrpAsn: 0.394 ± 0.84
0.394TrpPro: 0.394 ± 0.198
0.0TrpGln: 0.0 ± 0.0
0.394TrpArg: 0.394 ± 0.198
0.0TrpSer: 0.0 ± 0.0
1.182TrpThr: 1.182 ± 0.773
1.575TrpVal: 1.575 ± 0.693
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.969TyrAla: 1.969 ± 0.71
1.182TyrCys: 1.182 ± 0.773
3.151TyrAsp: 3.151 ± 0.974
1.575TyrGlu: 1.575 ± 0.791
1.969TyrPhe: 1.969 ± 1.008
2.363TyrGly: 2.363 ± 0.849
0.788TyrHis: 0.788 ± 0.396
5.908TyrIle: 5.908 ± 4.629
3.151TyrLys: 3.151 ± 0.992
3.545TyrLeu: 3.545 ± 1.411
0.394TyrMet: 0.394 ± 0.198
1.575TyrAsn: 1.575 ± 0.989
0.788TyrPro: 0.788 ± 1.064
0.394TyrGln: 0.394 ± 0.198
0.788TyrArg: 0.788 ± 0.396
1.575TyrSer: 1.575 ± 0.791
1.969TyrThr: 1.969 ± 0.749
1.969TyrVal: 1.969 ± 0.749
0.788TyrTrp: 0.788 ± 0.743
1.182TyrTyr: 1.182 ± 0.593
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2540 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski