Amino acid dipepetide frequency for Amasya cherry disease associated chrysovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.669AlaAla: 4.669 ± 0.439
1.373AlaCys: 1.373 ± 0.761
4.944AlaAsp: 4.944 ± 0.798
4.944AlaGlu: 4.944 ± 0.546
1.923AlaPhe: 1.923 ± 0.484
3.57AlaGly: 3.57 ± 0.771
1.099AlaHis: 1.099 ± 0.505
4.944AlaIle: 4.944 ± 1.522
6.042AlaLys: 6.042 ± 1.953
6.592AlaLeu: 6.592 ± 0.837
2.746AlaMet: 2.746 ± 0.602
2.746AlaAsn: 2.746 ± 0.337
3.021AlaPro: 3.021 ± 0.335
2.746AlaGln: 2.746 ± 0.717
4.944AlaArg: 4.944 ± 1.405
4.12AlaSer: 4.12 ± 1.29
6.042AlaThr: 6.042 ± 0.804
6.866AlaVal: 6.866 ± 1.945
0.824AlaTrp: 0.824 ± 0.548
2.472AlaTyr: 2.472 ± 0.945
0.0AlaXaa: 0.0 ± 0.0
Cys
0.824CysAla: 0.824 ± 0.259
0.275CysCys: 0.275 ± 0.263
1.099CysAsp: 1.099 ± 0.787
1.648CysGlu: 1.648 ± 0.434
0.275CysPhe: 0.275 ± 0.276
1.373CysGly: 1.373 ± 0.761
0.549CysHis: 0.549 ± 0.408
0.549CysIle: 0.549 ± 0.266
0.549CysLys: 0.549 ± 0.345
1.099CysLeu: 1.099 ± 0.399
1.099CysMet: 1.099 ± 0.365
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.275CysGln: 0.275 ± 0.204
2.472CysArg: 2.472 ± 0.85
1.373CysSer: 1.373 ± 0.498
0.0CysThr: 0.0 ± 0.0
1.648CysVal: 1.648 ± 0.35
0.549CysTrp: 0.549 ± 0.551
0.275CysTyr: 0.275 ± 0.204
0.0CysXaa: 0.0 ± 0.0
Asp
4.944AspAla: 4.944 ± 0.44
0.549AspCys: 0.549 ± 0.253
3.296AspAsp: 3.296 ± 0.867
4.944AspGlu: 4.944 ± 1.505
0.824AspPhe: 0.824 ± 0.406
5.218AspGly: 5.218 ± 1.212
0.824AspHis: 0.824 ± 0.192
4.12AspIle: 4.12 ± 0.727
6.042AspLys: 6.042 ± 0.872
4.669AspLeu: 4.669 ± 0.797
3.57AspMet: 3.57 ± 1.211
2.197AspAsn: 2.197 ± 0.55
1.923AspPro: 1.923 ± 0.633
1.099AspGln: 1.099 ± 0.6
3.845AspArg: 3.845 ± 0.884
3.296AspSer: 3.296 ± 0.916
2.197AspThr: 2.197 ± 0.709
6.042AspVal: 6.042 ± 1.528
3.296AspTrp: 3.296 ± 0.83
3.57AspTyr: 3.57 ± 0.533
0.0AspXaa: 0.0 ± 0.0
Glu
4.12GluAla: 4.12 ± 1.279
1.373GluCys: 1.373 ± 0.503
3.296GluAsp: 3.296 ± 0.633
5.493GluGlu: 5.493 ± 0.766
2.472GluPhe: 2.472 ± 0.93
3.845GluGly: 3.845 ± 0.656
1.373GluHis: 1.373 ± 0.531
2.472GluIle: 2.472 ± 0.284
7.141GluLys: 7.141 ± 1.595
4.944GluLeu: 4.944 ± 0.87
2.472GluMet: 2.472 ± 0.556
2.472GluAsn: 2.472 ± 0.339
3.296GluPro: 3.296 ± 1.123
2.746GluGln: 2.746 ± 0.422
6.042GluArg: 6.042 ± 1.456
2.197GluSer: 2.197 ± 0.639
4.12GluThr: 4.12 ± 1.05
6.592GluVal: 6.592 ± 0.631
1.923GluTrp: 1.923 ± 0.343
3.845GluTyr: 3.845 ± 0.723
0.0GluXaa: 0.0 ± 0.0
Phe
3.021PheAla: 3.021 ± 0.869
0.549PheCys: 0.549 ± 0.253
3.021PheAsp: 3.021 ± 1.518
2.472PheGlu: 2.472 ± 0.995
0.549PhePhe: 0.549 ± 0.408
2.197PheGly: 2.197 ± 0.288
1.099PheHis: 1.099 ± 0.816
0.824PheIle: 0.824 ± 0.453
2.472PheLys: 2.472 ± 0.577
0.824PheLeu: 0.824 ± 0.192
0.275PheMet: 0.275 ± 0.276
1.648PheAsn: 1.648 ± 0.611
0.275PhePro: 0.275 ± 0.276
0.275PheGln: 0.275 ± 0.263
0.824PheArg: 0.824 ± 0.534
2.472PheSer: 2.472 ± 0.697
1.648PheThr: 1.648 ± 0.556
2.197PheVal: 2.197 ± 0.85
0.275PheTrp: 0.275 ± 0.204
0.824PheTyr: 0.824 ± 0.271
0.0PheXaa: 0.0 ± 0.0
Gly
4.944GlyAla: 4.944 ± 1.14
2.472GlyCys: 2.472 ± 0.459
4.669GlyAsp: 4.669 ± 1.084
6.042GlyGlu: 6.042 ± 0.791
3.296GlyPhe: 3.296 ± 0.995
4.669GlyGly: 4.669 ± 0.439
1.099GlyHis: 1.099 ± 0.551
3.845GlyIle: 3.845 ± 0.59
4.12GlyLys: 4.12 ± 0.826
4.944GlyLeu: 4.944 ± 0.801
1.648GlyMet: 1.648 ± 0.961
1.923GlyAsn: 1.923 ± 0.397
0.549GlyPro: 0.549 ± 0.262
1.648GlyGln: 1.648 ± 0.434
3.57GlyArg: 3.57 ± 0.877
3.845GlySer: 3.845 ± 0.311
3.57GlyThr: 3.57 ± 0.564
5.493GlyVal: 5.493 ± 1.208
1.373GlyTrp: 1.373 ± 0.217
3.296GlyTyr: 3.296 ± 0.857
0.0GlyXaa: 0.0 ± 0.0
His
0.824HisAla: 0.824 ± 0.289
0.0HisCys: 0.0 ± 0.0
0.549HisAsp: 0.549 ± 0.253
1.648HisGlu: 1.648 ± 0.551
0.0HisPhe: 0.0 ± 0.0
1.923HisGly: 1.923 ± 0.695
0.275HisHis: 0.275 ± 0.204
1.099HisIle: 1.099 ± 0.374
1.373HisLys: 1.373 ± 0.788
1.923HisLeu: 1.923 ± 0.784
1.373HisMet: 1.373 ± 0.382
0.824HisAsn: 0.824 ± 0.406
0.0HisPro: 0.0 ± 0.0
0.549HisGln: 0.549 ± 0.262
1.373HisArg: 1.373 ± 0.761
0.549HisSer: 0.549 ± 0.253
1.648HisThr: 1.648 ± 0.811
1.648HisVal: 1.648 ± 0.249
0.275HisTrp: 0.275 ± 0.204
1.373HisTyr: 1.373 ± 0.382
0.0HisXaa: 0.0 ± 0.0
Ile
3.021IleAla: 3.021 ± 0.764
0.549IleCys: 0.549 ± 0.253
3.296IleAsp: 3.296 ± 0.385
3.021IleGlu: 3.021 ± 0.671
0.275IlePhe: 0.275 ± 0.263
3.296IleGly: 3.296 ± 1.19
0.549IleHis: 0.549 ± 0.408
1.099IleIle: 1.099 ± 0.945
4.394IleLys: 4.394 ± 1.443
2.472IleLeu: 2.472 ± 0.414
1.648IleMet: 1.648 ± 0.443
1.923IleAsn: 1.923 ± 1.051
3.296IlePro: 3.296 ± 0.5
0.824IleGln: 0.824 ± 0.259
2.746IleArg: 2.746 ± 0.757
2.472IleSer: 2.472 ± 0.511
4.12IleThr: 4.12 ± 1.182
2.746IleVal: 2.746 ± 0.156
0.275IleTrp: 0.275 ± 0.204
0.824IleTyr: 0.824 ± 0.453
0.0IleXaa: 0.0 ± 0.0
Lys
4.669LysAla: 4.669 ± 0.962
0.549LysCys: 0.549 ± 0.253
4.944LysAsp: 4.944 ± 1.067
4.669LysGlu: 4.669 ± 1.587
1.923LysPhe: 1.923 ± 0.731
5.493LysGly: 5.493 ± 1.199
2.472LysHis: 2.472 ± 0.184
1.099LysIle: 1.099 ± 0.586
5.493LysLys: 5.493 ± 0.574
7.416LysLeu: 7.416 ± 1.539
3.296LysMet: 3.296 ± 0.991
3.57LysAsn: 3.57 ± 1.476
3.845LysPro: 3.845 ± 1.367
1.373LysGln: 1.373 ± 0.468
3.021LysArg: 3.021 ± 0.679
4.12LysSer: 4.12 ± 0.57
2.746LysThr: 2.746 ± 0.63
5.768LysVal: 5.768 ± 0.365
1.923LysTrp: 1.923 ± 1.109
2.746LysTyr: 2.746 ± 0.542
0.0LysXaa: 0.0 ± 0.0
Leu
6.317LeuAla: 6.317 ± 1.565
2.472LeuCys: 2.472 ± 0.459
4.12LeuAsp: 4.12 ± 1.45
4.12LeuGlu: 4.12 ± 0.281
2.746LeuPhe: 2.746 ± 0.735
5.493LeuGly: 5.493 ± 2.0
1.373LeuHis: 1.373 ± 0.462
3.296LeuIle: 3.296 ± 1.077
4.944LeuLys: 4.944 ± 1.165
5.218LeuLeu: 5.218 ± 0.606
5.768LeuMet: 5.768 ± 1.104
4.669LeuAsn: 4.669 ± 0.982
4.12LeuPro: 4.12 ± 1.065
1.648LeuGln: 1.648 ± 0.361
3.296LeuArg: 3.296 ± 0.583
3.57LeuSer: 3.57 ± 0.913
3.57LeuThr: 3.57 ± 1.022
4.944LeuVal: 4.944 ± 1.389
1.373LeuTrp: 1.373 ± 0.973
2.746LeuTyr: 2.746 ± 0.646
0.0LeuXaa: 0.0 ± 0.0
Met
3.296MetAla: 3.296 ± 1.096
0.824MetCys: 0.824 ± 0.566
3.845MetAsp: 3.845 ± 1.397
2.197MetGlu: 2.197 ± 0.572
1.648MetPhe: 1.648 ± 0.976
1.923MetGly: 1.923 ± 0.833
0.824MetHis: 0.824 ± 0.566
2.472MetIle: 2.472 ± 0.239
3.57MetLys: 3.57 ± 0.197
2.746MetLeu: 2.746 ± 0.308
2.197MetMet: 2.197 ± 0.375
1.648MetAsn: 1.648 ± 0.35
3.021MetPro: 3.021 ± 0.44
1.648MetGln: 1.648 ± 0.562
2.472MetArg: 2.472 ± 1.33
4.669MetSer: 4.669 ± 0.705
2.472MetThr: 2.472 ± 0.856
3.021MetVal: 3.021 ± 0.758
0.549MetTrp: 0.549 ± 0.296
1.648MetTyr: 1.648 ± 0.385
0.0MetXaa: 0.0 ± 0.0
Asn
2.197AsnAla: 2.197 ± 0.397
0.0AsnCys: 0.0 ± 0.0
4.12AsnAsp: 4.12 ± 1.097
2.746AsnGlu: 2.746 ± 0.71
0.275AsnPhe: 0.275 ± 0.204
2.472AsnGly: 2.472 ± 0.383
0.824AsnHis: 0.824 ± 0.377
1.923AsnIle: 1.923 ± 0.72
3.296AsnLys: 3.296 ± 0.924
3.845AsnLeu: 3.845 ± 0.527
1.373AsnMet: 1.373 ± 0.169
0.549AsnAsn: 0.549 ± 0.291
1.099AsnPro: 1.099 ± 0.294
0.275AsnGln: 0.275 ± 0.263
3.296AsnArg: 3.296 ± 1.572
2.472AsnSer: 2.472 ± 0.514
2.472AsnThr: 2.472 ± 0.459
3.296AsnVal: 3.296 ± 1.088
1.373AsnTrp: 1.373 ± 0.169
1.373AsnTyr: 1.373 ± 0.462
0.0AsnXaa: 0.0 ± 0.0
Pro
3.57ProAla: 3.57 ± 1.161
0.275ProCys: 0.275 ± 0.276
3.021ProAsp: 3.021 ± 1.245
2.472ProGlu: 2.472 ± 0.697
1.099ProPhe: 1.099 ± 0.349
3.021ProGly: 3.021 ± 1.002
1.099ProHis: 1.099 ± 0.448
0.824ProIle: 0.824 ± 0.474
3.57ProLys: 3.57 ± 0.614
2.472ProLeu: 2.472 ± 0.882
0.549ProMet: 0.549 ± 0.473
1.373ProAsn: 1.373 ± 0.217
0.824ProPro: 0.824 ± 0.406
1.099ProGln: 1.099 ± 0.533
1.923ProArg: 1.923 ± 0.673
3.296ProSer: 3.296 ± 0.633
1.373ProThr: 1.373 ± 0.905
3.021ProVal: 3.021 ± 0.356
0.275ProTrp: 0.275 ± 0.276
0.824ProTyr: 0.824 ± 0.455
0.0ProXaa: 0.0 ± 0.0
Gln
1.648GlnAla: 1.648 ± 0.578
0.0GlnCys: 0.0 ± 0.0
1.648GlnAsp: 1.648 ± 0.95
1.373GlnGlu: 1.373 ± 0.468
0.824GlnPhe: 0.824 ± 0.192
2.197GlnGly: 2.197 ± 0.208
0.275GlnHis: 0.275 ± 0.204
1.923GlnIle: 1.923 ± 0.29
1.923GlnLys: 1.923 ± 0.907
1.373GlnLeu: 1.373 ± 0.98
1.923GlnMet: 1.923 ± 0.332
0.549GlnAsn: 0.549 ± 0.473
0.0GlnPro: 0.0 ± 0.0
1.099GlnGln: 1.099 ± 0.379
1.099GlnArg: 1.099 ± 0.774
1.373GlnSer: 1.373 ± 0.609
2.472GlnThr: 2.472 ± 0.392
0.824GlnVal: 0.824 ± 0.455
0.824GlnTrp: 0.824 ± 0.515
1.099GlnTyr: 1.099 ± 0.524
0.0GlnXaa: 0.0 ± 0.0
Arg
6.866ArgAla: 6.866 ± 1.847
1.099ArgCys: 1.099 ± 0.478
3.57ArgAsp: 3.57 ± 1.336
3.296ArgGlu: 3.296 ± 0.418
2.197ArgPhe: 2.197 ± 0.934
4.669ArgGly: 4.669 ± 0.281
1.373ArgHis: 1.373 ± 0.382
2.472ArgIle: 2.472 ± 0.574
3.296ArgLys: 3.296 ± 0.777
3.021ArgLeu: 3.021 ± 0.789
2.746ArgMet: 2.746 ± 0.525
1.923ArgAsn: 1.923 ± 0.633
1.923ArgPro: 1.923 ± 0.755
2.472ArgGln: 2.472 ± 0.587
4.944ArgArg: 4.944 ± 1.058
4.394ArgSer: 4.394 ± 2.289
3.021ArgThr: 3.021 ± 0.441
4.394ArgVal: 4.394 ± 0.692
0.824ArgTrp: 0.824 ± 0.289
3.845ArgTyr: 3.845 ± 0.787
0.0ArgXaa: 0.0 ± 0.0
Ser
5.768SerAla: 5.768 ± 0.715
1.373SerCys: 1.373 ± 0.512
4.12SerAsp: 4.12 ± 1.281
4.944SerGlu: 4.944 ± 0.767
1.373SerPhe: 1.373 ± 0.609
4.394SerGly: 4.394 ± 0.756
0.549SerHis: 0.549 ± 0.345
2.197SerIle: 2.197 ± 0.697
3.57SerLys: 3.57 ± 0.754
4.669SerLeu: 4.669 ± 1.198
2.472SerMet: 2.472 ± 0.637
2.197SerAsn: 2.197 ± 0.55
1.648SerPro: 1.648 ± 1.137
1.373SerGln: 1.373 ± 0.217
3.57SerArg: 3.57 ± 1.483
3.57SerSer: 3.57 ± 1.446
4.394SerThr: 4.394 ± 0.753
6.317SerVal: 6.317 ± 1.348
0.824SerTrp: 0.824 ± 0.474
3.021SerTyr: 3.021 ± 0.889
0.0SerXaa: 0.0 ± 0.0
Thr
3.845ThrAla: 3.845 ± 1.157
0.824ThrCys: 0.824 ± 0.259
0.824ThrAsp: 0.824 ± 0.289
4.394ThrGlu: 4.394 ± 0.996
2.197ThrPhe: 2.197 ± 0.697
4.944ThrGly: 4.944 ± 0.646
1.099ThrHis: 1.099 ± 0.294
3.57ThrIle: 3.57 ± 0.926
2.197ThrLys: 2.197 ± 0.838
5.768ThrLeu: 5.768 ± 0.584
3.296ThrMet: 3.296 ± 0.594
3.296ThrAsn: 3.296 ± 0.74
2.746ThrPro: 2.746 ± 0.669
1.099ThrGln: 1.099 ± 0.399
3.57ThrArg: 3.57 ± 0.669
4.12ThrSer: 4.12 ± 1.29
3.296ThrThr: 3.296 ± 1.057
2.472ThrVal: 2.472 ± 0.459
0.549ThrTrp: 0.549 ± 0.253
1.923ThrTyr: 1.923 ± 0.361
0.0ThrXaa: 0.0 ± 0.0
Val
6.592ValAla: 6.592 ± 1.358
0.549ValCys: 0.549 ± 0.291
5.493ValAsp: 5.493 ± 0.474
6.592ValGlu: 6.592 ± 1.212
3.021ValPhe: 3.021 ± 0.712
3.845ValGly: 3.845 ± 0.935
1.099ValHis: 1.099 ± 0.816
2.746ValIle: 2.746 ± 1.063
4.944ValLys: 4.944 ± 0.631
4.944ValLeu: 4.944 ± 1.522
4.12ValMet: 4.12 ± 0.72
4.12ValAsn: 4.12 ± 1.212
3.021ValPro: 3.021 ± 0.828
1.648ValGln: 1.648 ± 0.556
4.394ValArg: 4.394 ± 0.119
7.141ValSer: 7.141 ± 2.24
3.845ValThr: 3.845 ± 1.069
7.69ValVal: 7.69 ± 0.506
1.648ValTrp: 1.648 ± 0.725
1.648ValTyr: 1.648 ± 0.659
0.0ValXaa: 0.0 ± 0.0
Trp
1.923TrpAla: 1.923 ± 0.88
0.0TrpCys: 0.0 ± 0.0
1.648TrpAsp: 1.648 ± 0.556
1.099TrpGlu: 1.099 ± 0.363
0.275TrpPhe: 0.275 ± 0.263
0.824TrpGly: 0.824 ± 0.192
0.549TrpHis: 0.549 ± 0.345
0.549TrpIle: 0.549 ± 0.345
0.824TrpLys: 0.824 ± 0.271
3.845TrpLeu: 3.845 ± 0.852
0.549TrpMet: 0.549 ± 0.477
0.275TrpAsn: 0.275 ± 0.276
0.549TrpPro: 0.549 ± 0.262
0.275TrpGln: 0.275 ± 0.204
1.923TrpArg: 1.923 ± 0.29
0.824TrpSer: 0.824 ± 0.429
1.648TrpThr: 1.648 ± 0.353
1.648TrpVal: 1.648 ± 0.61
0.824TrpTrp: 0.824 ± 0.534
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.57TyrAla: 3.57 ± 0.433
0.824TyrCys: 0.824 ± 0.289
4.944TyrAsp: 4.944 ± 0.226
4.12TyrGlu: 4.12 ± 0.529
0.549TyrPhe: 0.549 ± 0.253
1.923TyrGly: 1.923 ± 0.343
0.824TyrHis: 0.824 ± 0.259
0.824TyrIle: 0.824 ± 0.192
1.373TyrLys: 1.373 ± 0.522
3.021TyrLeu: 3.021 ± 0.656
3.296TyrMet: 3.296 ± 1.011
1.373TyrAsn: 1.373 ± 0.377
0.824TyrPro: 0.824 ± 0.474
0.275TyrGln: 0.275 ± 0.276
3.021TyrArg: 3.021 ± 0.356
2.472TyrSer: 2.472 ± 0.998
1.373TyrThr: 1.373 ± 0.442
2.472TyrVal: 2.472 ± 0.778
0.275TyrTrp: 0.275 ± 0.204
1.373TyrTyr: 1.373 ± 0.503
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3642 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski