Strongylocentrotus purpuratus (Purple sea urchin)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Echinodermata; Eleutherozoa; Echinozoa; Echinoidea; Euechinoidea; Echinacea; Camarodonta; Echinidea; Strongylocentrotidae; Strongylocentrotus

Average proteome isoelectric point is 6.29

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 34423 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
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* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    

Protein with the lowest isoelectric point:
>tr|A0A7M7NH22|A0A7M7NH22_STRPU Uncharacterized protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
MM1 pKa = 7.7LGQKK5 pKa = 7.61VHH7 pKa = 7.11PFRR10 pKa = 11.84ASHH13 pKa = 6.78PPRR16 pKa = 11.84TLLHH20 pKa = 5.36QVQDD24 pKa = 3.33KK25 pKa = 10.41TDD27 pKa = 3.4AFKK30 pKa = 10.49MISKK34 pKa = 8.73TLGLSGPHH42 pKa = 6.36PVLPKK47 pKa = 10.65DD48 pKa = 3.53NQTVFQKK55 pKa = 11.04DD56 pKa = 3.83HH57 pKa = 7.53LSMINQKK64 pKa = 9.63CQNPCEE70 pKa = 4.42PNPCLNQGACSGSIGNTTFTCVCTAGFSGQNCGTDD105 pKa = 3.05RR106 pKa = 11.84ASNDD110 pKa = 2.9APQFVYY116 pKa = 9.5TQDD119 pKa = 3.31PTLKK123 pKa = 8.77VTEE126 pKa = 4.39GQSPSIVVFTLNATDD141 pKa = 4.36PDD143 pKa = 4.37GDD145 pKa = 4.52LIIYY149 pKa = 10.18DD150 pKa = 4.71LFDD153 pKa = 4.43DD154 pKa = 4.58AARR157 pKa = 11.84SIFAINQFTGQLYY170 pKa = 10.33ASPGLDD176 pKa = 3.17YY177 pKa = 11.5EE178 pKa = 4.38MLGNQVIITVSVTDD192 pKa = 5.17GINDD196 pKa = 3.9PVPQTIYY203 pKa = 10.99VQITDD208 pKa = 3.95VNDD211 pKa = 3.36IAPTFTNLPNITYY224 pKa = 9.59VFEE227 pKa = 4.14NATIGSEE234 pKa = 4.54LYY236 pKa = 10.28QVITTDD242 pKa = 2.78EE243 pKa = 4.05DD244 pKa = 3.76TFYY247 pKa = 11.36GGFVTYY253 pKa = 10.45SILLVTPSNPGSAPNNYY270 pKa = 9.31FSIGEE275 pKa = 4.02TDD277 pKa = 5.05GIIQLATSLNYY288 pKa = 10.3EE289 pKa = 4.65EE290 pKa = 4.22IQQYY294 pKa = 9.18FVTVVARR301 pKa = 11.84DD302 pKa = 3.66YY303 pKa = 10.7GTGDD307 pKa = 3.3TSLSSTATLTVSVLDD322 pKa = 3.86IQDD325 pKa = 3.76TNPVFLNIPYY335 pKa = 10.38DD336 pKa = 3.61VTIPEE341 pKa = 4.34TLPVGSTVQTIRR353 pKa = 11.84ATDD356 pKa = 3.79PDD358 pKa = 4.57TNNGNIITYY367 pKa = 9.81NLVVSDD373 pKa = 3.66SQGYY377 pKa = 7.92FVIDD381 pKa = 3.34QTTGIITVNSQMDD394 pKa = 3.76RR395 pKa = 11.84DD396 pKa = 4.23NPVLPATYY404 pKa = 9.28PLIVSAVEE412 pKa = 4.02TSSGGVSFAQVSFNVTVSPANDD434 pKa = 3.56EE435 pKa = 4.46PPSFDD440 pKa = 3.37QNSYY444 pKa = 9.93SASIPEE450 pKa = 4.11SASINSQLPITITVDD465 pKa = 3.48DD466 pKa = 5.07GDD468 pKa = 5.72LITDD472 pKa = 3.61STVTVSLQNGNSVPFRR488 pKa = 11.84VSPTQVVGSGTIDD501 pKa = 3.19ILITQPLDD509 pKa = 3.33FEE511 pKa = 5.75NNQQYY516 pKa = 8.34TLQLQAVDD524 pKa = 5.25GDD526 pKa = 4.44GQDD529 pKa = 3.84LAPLMVTVTDD539 pKa = 3.91VNDD542 pKa = 3.6NNPVFINRR550 pKa = 11.84PIDD553 pKa = 3.73NIYY556 pKa = 10.33RR557 pKa = 11.84GSINEE562 pKa = 3.81NDD564 pKa = 3.4QTGTFIVQVSTTDD577 pKa = 3.35ADD579 pKa = 3.94SGSNAAVTYY588 pKa = 10.16SIISGNINNVFTINPTSGAITNTQILGPNTPQTYY622 pKa = 8.14TLSVRR627 pKa = 11.84ATNPTPGVAPATGTSTSTVIITVNDD652 pKa = 3.7VNDD655 pKa = 3.74SPPRR659 pKa = 11.84FSDD662 pKa = 3.09NEE664 pKa = 3.96YY665 pKa = 9.53TVFINEE671 pKa = 4.02AAQVGTTVTRR681 pKa = 11.84ITATDD686 pKa = 3.3EE687 pKa = 4.94DD688 pKa = 4.37IPEE691 pKa = 4.48GDD693 pKa = 3.55RR694 pKa = 11.84LTYY697 pKa = 10.24IITAGNQGGHH707 pKa = 5.11FQINPVSGDD716 pKa = 3.43VTLLRR721 pKa = 11.84QLDD724 pKa = 3.91RR725 pKa = 11.84EE726 pKa = 4.58LEE728 pKa = 4.28SQHH731 pKa = 6.24NLTIRR736 pKa = 11.84ATDD739 pKa = 3.17QGAPPQSATTTLKK752 pKa = 11.1VIVLDD757 pKa = 4.43FNDD760 pKa = 5.53NAPQWNPQSYY770 pKa = 10.37VDD772 pKa = 4.93SILEE776 pKa = 3.97NVPVNTFVLQVVATDD791 pKa = 3.71NDD793 pKa = 3.33QGTNADD799 pKa = 4.11LSFTINNANNVPFVIDD815 pKa = 3.51DD816 pKa = 3.41QGNIRR821 pKa = 11.84TSGPLNRR828 pKa = 11.84EE829 pKa = 3.63TVPQYY834 pKa = 11.46NFLVTVLDD842 pKa = 3.93NGSPQQAGNPPATITINILDD862 pKa = 4.34VNDD865 pKa = 4.14EE866 pKa = 4.33PPVLDD871 pKa = 3.7RR872 pKa = 11.84NAYY875 pKa = 9.02EE876 pKa = 4.16FTGSEE881 pKa = 3.95DD882 pKa = 3.48VNFNTFVGQVTATDD896 pKa = 4.17PDD898 pKa = 3.64LSGTLTYY905 pKa = 10.47TFVPADD911 pKa = 3.59PDD913 pKa = 3.7FNYY916 pKa = 10.03ISGTIRR922 pKa = 11.84TNTQLDD928 pKa = 3.66ANQQQVYY935 pKa = 9.32QMTVFASDD943 pKa = 3.92GVQNSQSAPVTINVLDD959 pKa = 4.37VNTQAPFFGLGTYY972 pKa = 9.46VKK974 pKa = 9.96SLPEE978 pKa = 4.34DD979 pKa = 3.56SPFQTLVVDD988 pKa = 5.97LNATDD993 pKa = 4.61PDD995 pKa = 3.69NGNIGLIIYY1004 pKa = 9.89SFEE1007 pKa = 4.2SLSRR1011 pKa = 11.84TQGPFTVEE1019 pKa = 4.29PYY1021 pKa = 10.13TGVIDD1026 pKa = 4.05ISTTAGLDD1034 pKa = 3.15RR1035 pKa = 11.84EE1036 pKa = 4.56TQDD1039 pKa = 3.48EE1040 pKa = 4.61YY1041 pKa = 11.5TMIVIAVDD1049 pKa = 3.78QPVSGQPMTGTATVSVIVTDD1069 pKa = 4.06VNDD1072 pKa = 3.54NAPTFRR1078 pKa = 11.84DD1079 pKa = 3.02ISYY1082 pKa = 9.62EE1083 pKa = 3.77KK1084 pKa = 10.65SIFEE1088 pKa = 3.9NHH1090 pKa = 6.87PLGSNILTVQADD1102 pKa = 3.95DD1103 pKa = 4.93LDD1105 pKa = 5.33LGVNAVVLYY1114 pKa = 10.2RR1115 pKa = 11.84IISGNNNNLFNVDD1128 pKa = 3.01GQGNINLGNTPLDD1141 pKa = 3.69RR1142 pKa = 11.84EE1143 pKa = 4.25MQDD1146 pKa = 2.97QYY1148 pKa = 11.93FLIVQAYY1155 pKa = 9.95NSDD1158 pKa = 3.49LSVGTNEE1165 pKa = 4.2APVIIIILDD1174 pKa = 3.64INDD1177 pKa = 3.6VTPLFQQQNYY1187 pKa = 8.34YY1188 pKa = 10.64RR1189 pKa = 11.84PDD1191 pKa = 3.31LSEE1194 pKa = 4.47NSPSGTPVLQVFAQDD1209 pKa = 3.32QDD1211 pKa = 3.66LDD1213 pKa = 4.03LAGDD1217 pKa = 3.68VQYY1220 pKa = 11.76SLIGNPNFLTINSDD1234 pKa = 3.38TGVISVNGPIADD1246 pKa = 3.96LSGSRR1251 pKa = 11.84NFTMTVRR1258 pKa = 11.84ATDD1261 pKa = 3.26QASPFLRR1268 pKa = 11.84GMATVTVTVVDD1279 pKa = 3.94DD1280 pKa = 3.99TVTIPIFTLSRR1291 pKa = 11.84YY1292 pKa = 7.59PATVNEE1298 pKa = 4.55NVNADD1303 pKa = 3.81TPVTRR1308 pKa = 11.84VSATLNGNPAGITYY1322 pKa = 10.3AIDD1325 pKa = 3.91PNASPAVLEE1334 pKa = 3.92IFKK1337 pKa = 10.42IEE1339 pKa = 4.34EE1340 pKa = 4.15NTGHH1344 pKa = 6.55ITTEE1348 pKa = 3.94GAIDD1352 pKa = 3.74RR1353 pKa = 11.84EE1354 pKa = 4.39VEE1356 pKa = 3.79DD1357 pKa = 5.81FYY1359 pKa = 11.73AFTVFAYY1366 pKa = 10.31HH1367 pKa = 7.12EE1368 pKa = 4.88DD1369 pKa = 3.67SVAPGSTSVWVNILDD1384 pKa = 4.24EE1385 pKa = 4.63NDD1387 pKa = 3.71NPPEE1391 pKa = 4.68FITVPPSPVSVQEE1404 pKa = 4.02NTGGNVPVGVFRR1416 pKa = 11.84ATDD1419 pKa = 3.51PDD1421 pKa = 3.64AGINAQMTFTISGAGSNFFNVFQTAYY1447 pKa = 9.74GGGTIVVTSPLDD1459 pKa = 3.35RR1460 pKa = 11.84EE1461 pKa = 4.23RR1462 pKa = 11.84QDD1464 pKa = 4.54FYY1466 pKa = 11.6QLTVTATDD1474 pKa = 3.52GGNPSLSSSFPLNITVTDD1492 pKa = 3.68VNDD1495 pKa = 4.05NYY1497 pKa = 10.63PIWTRR1502 pKa = 11.84NVYY1505 pKa = 9.99EE1506 pKa = 4.4GSINEE1511 pKa = 4.26NNFTSNPIITVMVNDD1526 pKa = 4.9LDD1528 pKa = 4.79LPSSNNFEE1536 pKa = 4.18YY1537 pKa = 10.7SIIAGDD1543 pKa = 3.67PMGMFEE1549 pKa = 4.51INSNGEE1555 pKa = 3.85ITVSSLLDD1563 pKa = 3.33RR1564 pKa = 11.84EE1565 pKa = 4.27QQEE1568 pKa = 4.95TYY1570 pKa = 10.8QLTIEE1575 pKa = 5.87LIDD1578 pKa = 3.74QTNSPPARR1586 pKa = 11.84TTTLAIITVGDD1597 pKa = 3.98EE1598 pKa = 4.21NDD1600 pKa = 3.27NTPIFDD1606 pKa = 3.6EE1607 pKa = 4.3TVIRR1611 pKa = 11.84VDD1613 pKa = 3.42VTEE1616 pKa = 5.22GPSSQNIPVYY1626 pKa = 10.12MLTANDD1632 pKa = 3.58IDD1634 pKa = 4.39LGLNRR1639 pKa = 11.84DD1640 pKa = 3.59IIYY1643 pKa = 10.39AIGSQQPQSHH1653 pKa = 5.44FQINIVTGMISTTTALDD1670 pKa = 3.17WEE1672 pKa = 4.9TISEE1676 pKa = 4.21YY1677 pKa = 10.68TLIVTATDD1685 pKa = 3.42QSPTEE1690 pKa = 4.22PRR1692 pKa = 11.84TGTATVIVSVNDD1704 pKa = 3.61INDD1707 pKa = 4.17GAPMFVRR1714 pKa = 11.84DD1715 pKa = 3.58VYY1717 pKa = 11.18GPYY1720 pKa = 10.27SVVEE1724 pKa = 4.25EE1725 pKa = 4.37VSNSYY1730 pKa = 10.32IDD1732 pKa = 4.12SFQATDD1738 pKa = 3.52TDD1740 pKa = 3.39QGQAGTVTYY1749 pKa = 10.09HH1750 pKa = 7.34VIGQYY1755 pKa = 11.27SNLFFIQPQTGVLTIRR1771 pKa = 11.84PDD1773 pKa = 3.02RR1774 pKa = 11.84ALNYY1778 pKa = 7.52EE1779 pKa = 4.59TITQFNITVVAMDD1792 pKa = 3.97MGNPVLSSSTVVGINVININDD1813 pKa = 3.69HH1814 pKa = 5.2TPIFEE1819 pKa = 4.95GIPYY1823 pKa = 9.35TITLSKK1829 pKa = 10.56NISAGSLAYY1838 pKa = 9.81VVRR1841 pKa = 11.84ATDD1844 pKa = 3.52DD1845 pKa = 3.44DD1846 pKa = 4.44AGIFGEE1852 pKa = 4.31VRR1854 pKa = 11.84YY1855 pKa = 10.21QITDD1859 pKa = 3.2GNTDD1863 pKa = 3.55NIFRR1867 pKa = 11.84IDD1869 pKa = 3.48QTTGEE1874 pKa = 4.39VFVQGLLEE1882 pKa = 4.34TGTYY1886 pKa = 9.88RR1887 pKa = 11.84LVVEE1891 pKa = 5.15ARR1893 pKa = 11.84DD1894 pKa = 3.89TPGDD1898 pKa = 3.73IPSSRR1903 pKa = 11.84ASSTTLTIVVTDD1915 pKa = 3.93IGDD1918 pKa = 4.21FAPTFPGSSLFTGNVFEE1935 pKa = 4.81NSPVGQPITMIPPIRR1950 pKa = 11.84AINSDD1955 pKa = 2.9ATGQLVYY1962 pKa = 10.31TITGPDD1968 pKa = 3.27SQTFMINQLSAGIQVNGPLDD1988 pKa = 4.18RR1989 pKa = 11.84EE1990 pKa = 4.3TKK1992 pKa = 10.24DD1993 pKa = 3.48FYY1995 pKa = 10.66EE1996 pKa = 4.26FRR1998 pKa = 11.84VIVTDD2003 pKa = 3.55SMGMTAEE2010 pKa = 4.29GTVHH2014 pKa = 7.1INVLDD2019 pKa = 4.08VNDD2022 pKa = 4.69FAPAFNDD2029 pKa = 3.14SVYY2032 pKa = 11.21NFTIPEE2038 pKa = 4.04NSPGGYY2044 pKa = 9.5YY2045 pKa = 10.43VGGVTAYY2052 pKa = 10.53DD2053 pKa = 3.75LDD2055 pKa = 4.47GDD2057 pKa = 4.02NVNFFIQTGGEE2068 pKa = 4.05DD2069 pKa = 3.25KK2070 pKa = 10.97FDD2072 pKa = 3.35IGGTSEE2078 pKa = 4.79TITVTPGAVLDD2089 pKa = 4.11RR2090 pKa = 11.84EE2091 pKa = 4.3EE2092 pKa = 4.48KK2093 pKa = 10.35PFYY2096 pKa = 9.72TLTVMVSDD2104 pKa = 4.84LRR2106 pKa = 11.84NPPLSGTATVYY2117 pKa = 10.82INLIDD2122 pKa = 4.86INDD2125 pKa = 3.98SPPKK2129 pKa = 9.32FTASFLDD2136 pKa = 3.83QIISIPEE2143 pKa = 3.89DD2144 pKa = 3.68TPGNTLVTAVTATDD2158 pKa = 4.45DD2159 pKa = 4.7DD2160 pKa = 4.76LNSNINYY2167 pKa = 9.69RR2168 pKa = 11.84IVSVSVYY2175 pKa = 10.95DD2176 pKa = 4.08EE2177 pKa = 5.22DD2178 pKa = 5.79DD2179 pKa = 3.46VDD2181 pKa = 3.38ITSFFDD2187 pKa = 3.25YY2188 pKa = 9.53RR2189 pKa = 11.84TVFSLNPTNGNITLTSPVDD2208 pKa = 3.47RR2209 pKa = 11.84EE2210 pKa = 4.19VTEE2213 pKa = 4.25KK2214 pKa = 10.71FVFSISARR2222 pKa = 11.84DD2223 pKa = 3.72LNSQNPIFGTSQEE2236 pKa = 4.17NAQVTILITDD2246 pKa = 3.35INDD2249 pKa = 3.11NHH2251 pKa = 7.25PAFQPPGTTFILRR2264 pKa = 11.84QLPEE2268 pKa = 4.11SFGAGSPIPGNLLALDD2284 pKa = 4.68PDD2286 pKa = 4.07LGLNGKK2292 pKa = 8.61VMYY2295 pKa = 10.36IIQDD2299 pKa = 3.49PSGVPVTIDD2308 pKa = 3.16QNTGQLTLLVTVDD2321 pKa = 4.84RR2322 pKa = 11.84EE2323 pKa = 4.02QQPWVNLTVLAVDD2336 pKa = 4.28KK2337 pKa = 8.22GTPSLNTSIPVYY2349 pKa = 10.91LEE2351 pKa = 4.72IIDD2354 pKa = 5.01NNDD2357 pKa = 3.06NNPVFGAQSHH2367 pKa = 5.77TPTIIEE2373 pKa = 4.33SAPIGAFVFNVNATDD2388 pKa = 3.87ADD2390 pKa = 4.06SGGSGQVTYY2399 pKa = 11.29SLIGGDD2405 pKa = 4.0GKK2407 pKa = 9.91FTINQDD2413 pKa = 3.11TGVITLLQQVDD2424 pKa = 4.22KK2425 pKa = 9.36EE2426 pKa = 4.69TQSQHH2431 pKa = 4.85MLTVFARR2438 pKa = 11.84DD2439 pKa = 3.57NPGDD2443 pKa = 4.05SEE2445 pKa = 4.41DD2446 pKa = 3.92SRR2448 pKa = 11.84TGSTTVIVNVLDD2460 pKa = 4.35ANEE2463 pKa = 4.23FPPVVTQPIFTINEE2477 pKa = 3.87GGIGGEE2483 pKa = 3.89VVGIIEE2489 pKa = 5.56AYY2491 pKa = 10.59DD2492 pKa = 4.05PDD2494 pKa = 6.17DD2495 pKa = 5.41PDD2497 pKa = 5.59DD2498 pKa = 4.9PNQSLYY2504 pKa = 10.59YY2505 pKa = 10.16VVVSSQPEE2513 pKa = 3.98VGSTLFIINNVTGEE2527 pKa = 4.23IITTGPLDD2535 pKa = 4.18RR2536 pKa = 11.84DD2537 pKa = 4.01SGLHH2541 pKa = 5.88PARR2544 pKa = 11.84VDD2546 pKa = 3.48LDD2548 pKa = 4.5LIVYY2552 pKa = 10.51DD2553 pKa = 5.29DD2554 pKa = 4.57GNPNLGTPTTAIIYY2568 pKa = 10.58INDD2571 pKa = 3.86LNDD2574 pKa = 3.24NQPIFDD2580 pKa = 4.03RR2581 pKa = 11.84PLYY2584 pKa = 10.59DD2585 pKa = 3.28VTVVEE2590 pKa = 4.75GQYY2593 pKa = 10.65NDD2595 pKa = 4.66PIITVVANDD2604 pKa = 3.93PDD2606 pKa = 3.79QNSNLRR2612 pKa = 11.84YY2613 pKa = 9.87KK2614 pKa = 10.52ILGGNLNNTFVLVDD2628 pKa = 3.72GGLIPVKK2635 pKa = 10.19PLDD2638 pKa = 3.89FEE2640 pKa = 4.7TFTNYY2645 pKa = 10.82NLTVVVTDD2653 pKa = 4.15DD2654 pKa = 3.34SGNRR2658 pKa = 11.84DD2659 pKa = 3.26TTYY2662 pKa = 11.16VAVTVTDD2669 pKa = 4.48ANDD2672 pKa = 3.62HH2673 pKa = 6.31NPTFVPDD2680 pKa = 4.56LYY2682 pKa = 11.2SLSVTEE2688 pKa = 4.7NEE2690 pKa = 4.32PPGTQVGVVMTIDD2703 pKa = 4.22GDD2705 pKa = 4.1TLPEE2709 pKa = 4.08YY2710 pKa = 10.66TDD2712 pKa = 3.65IIYY2715 pKa = 9.01TILTGNGLRR2724 pKa = 11.84NFTINSTTGIINTATILDD2742 pKa = 3.83RR2743 pKa = 11.84EE2744 pKa = 4.39KK2745 pKa = 10.06TSEE2748 pKa = 4.08YY2749 pKa = 10.62VLTIGAEE2756 pKa = 4.11NPVGGTTGTATVSIIVRR2773 pKa = 11.84DD2774 pKa = 4.05VNDD2777 pKa = 3.35NTPTFEE2783 pKa = 4.33EE2784 pKa = 4.1NPYY2787 pKa = 10.08TSTVTTNTLLVDD2799 pKa = 3.49VHH2801 pKa = 8.14ANDD2804 pKa = 4.41PDD2806 pKa = 3.56EE2807 pKa = 4.78GGNGIVIYY2815 pKa = 9.83EE2816 pKa = 4.0IVSGNEE2822 pKa = 3.8DD2823 pKa = 3.23NRR2825 pKa = 11.84FTIDD2829 pKa = 2.99NRR2831 pKa = 11.84TGVITLVNPLEE2842 pKa = 4.32SQLIRR2847 pKa = 11.84NYY2849 pKa = 8.04TLVVIGHH2856 pKa = 6.93DD2857 pKa = 3.48LGNPRR2862 pKa = 11.84LQSNTTVDD2870 pKa = 3.81LRR2872 pKa = 11.84INYY2875 pKa = 9.5LGLNAPPSFVRR2886 pKa = 11.84PNQGSTVFITEE2897 pKa = 4.01NNPLGLLIINAFAVDD2912 pKa = 4.48DD2913 pKa = 4.18DD2914 pKa = 4.34VGANGVVDD2922 pKa = 5.05YY2923 pKa = 11.33SILPNFDD2930 pKa = 3.62YY2931 pKa = 11.32SDD2933 pKa = 3.69FTIDD2937 pKa = 4.36PVTGDD2942 pKa = 2.97ITILVSADD2950 pKa = 3.75RR2951 pKa = 11.84EE2952 pKa = 4.42IKK2954 pKa = 10.37DD2955 pKa = 3.68SYY2957 pKa = 10.02TLTVVATDD2965 pKa = 3.52RR2966 pKa = 11.84GDD2968 pKa = 3.97PNLSTSSTFVIRR2980 pKa = 11.84VLDD2983 pKa = 4.19EE2984 pKa = 4.95NDD2986 pKa = 4.14DD2987 pKa = 3.78NPAFPRR2993 pKa = 11.84PDD2995 pKa = 3.11GMNNPIVLNLNVFEE3009 pKa = 4.61NANISDD3015 pKa = 4.02LVGTVDD3021 pKa = 4.37GAIDD3025 pKa = 4.57LDD3027 pKa = 4.29LGVNGQIFYY3036 pKa = 10.27HH3037 pKa = 6.82IVDD3040 pKa = 3.96STVGGIFVINSTTGVVTVNGTLDD3063 pKa = 3.46RR3064 pKa = 11.84EE3065 pKa = 4.68DD3066 pKa = 3.85IGVHH3070 pKa = 5.75TIYY3073 pKa = 10.64ILATNDD3079 pKa = 2.65ATYY3082 pKa = 11.35NRR3084 pKa = 11.84TGPYY3088 pKa = 10.05NVLDD3092 pKa = 4.58NISLKK3097 pKa = 8.86EE3098 pKa = 4.02VKK3100 pKa = 8.72ITLLDD3105 pKa = 3.65INDD3108 pKa = 3.91NEE3110 pKa = 4.38FTSTVKK3116 pKa = 10.28SAYY3119 pKa = 10.35ACMFDD3124 pKa = 4.97NPCQNEE3130 pKa = 4.93GICMEE3135 pKa = 5.34DD3136 pKa = 3.4EE3137 pKa = 4.82DD3138 pKa = 5.13NPGDD3142 pKa = 4.06VKK3144 pKa = 10.97CEE3146 pKa = 4.01CPDD3149 pKa = 3.29EE3150 pKa = 4.45YY3151 pKa = 11.48GGLYY3155 pKa = 10.38CEE3157 pKa = 4.25EE3158 pKa = 5.08SIPNACMFDD3167 pKa = 3.65NPCQNEE3173 pKa = 4.72GTCMDD3178 pKa = 5.32DD3179 pKa = 3.43EE3180 pKa = 5.31DD3181 pKa = 4.67NPGNVKK3187 pKa = 9.8CVCLDD3192 pKa = 3.78GYY3194 pKa = 11.31SGLDD3198 pKa = 3.47CGEE3201 pKa = 3.65ATPRR3205 pKa = 11.84YY3206 pKa = 9.33NLNILIAALAGLAVFMSLVSLIMICAKK3233 pKa = 10.15ARR3235 pKa = 11.84KK3236 pKa = 7.36TSSARR3241 pKa = 11.84NEE3243 pKa = 4.2LNVSDD3248 pKa = 3.97SCQRR3252 pKa = 11.84PPQSVNNQPDD3262 pKa = 3.58LEE3264 pKa = 4.5AVANEE3269 pKa = 4.04PNVPNGPMRR3278 pKa = 11.84EE3279 pKa = 4.1NTDD3282 pKa = 3.15MANRR3286 pKa = 11.84PLPSLPDD3293 pKa = 3.21QPGAIVHH3300 pKa = 7.16DD3301 pKa = 4.32YY3302 pKa = 9.59ATTLRR3307 pKa = 11.84PLMRR3311 pKa = 11.84QRR3313 pKa = 11.84SNHH3316 pKa = 5.26SFVV3319 pKa = 3.29

Molecular weight:
358.59 kDa
Isoelectric point according different methods:






Protein with the highest isoelectric point:
>tr|A0A7M7RH65|A0A7M7RH65_STRPU Methyltransferase-like protein OS=Strongylocentrotus purpuratus OX=7668 PE=3 SV=1
MM1 pKa = 7.54PASPQKK7 pKa = 10.26RR8 pKa = 11.84AASPRR13 pKa = 11.84RR14 pKa = 11.84SPKK17 pKa = 9.72KK18 pKa = 10.34SPRR21 pKa = 11.84KK22 pKa = 9.49SPKK25 pKa = 8.72KK26 pKa = 9.86SPRR29 pKa = 11.84KK30 pKa = 9.3RR31 pKa = 11.84SASPRR36 pKa = 11.84RR37 pKa = 11.84RR38 pKa = 11.84RR39 pKa = 11.84RR40 pKa = 11.84SNARR44 pKa = 11.84AATHH48 pKa = 6.22PPVLEE53 pKa = 4.44MIRR56 pKa = 11.84AAITAMKK63 pKa = 9.21EE64 pKa = 3.82RR65 pKa = 11.84RR66 pKa = 11.84GSSVSKK72 pKa = 9.47IKK74 pKa = 10.74SYY76 pKa = 10.5IAANYY81 pKa = 8.17RR82 pKa = 11.84VNMANLQPHH91 pKa = 6.61IRR93 pKa = 11.84RR94 pKa = 11.84ALRR97 pKa = 11.84SGVTSGALKK106 pKa = 10.4QVTGTGATGRR116 pKa = 11.84FRR118 pKa = 11.84VGVVPRR124 pKa = 11.84PKK126 pKa = 10.21KK127 pKa = 10.12ARR129 pKa = 11.84KK130 pKa = 7.4TSAAAAAKK138 pKa = 9.47KK139 pKa = 9.84QRR141 pKa = 11.84ARR143 pKa = 11.84ARR145 pKa = 11.84AVAKK149 pKa = 9.88RR150 pKa = 11.84AKK152 pKa = 9.91AAARR156 pKa = 11.84RR157 pKa = 11.84KK158 pKa = 9.39AAAAKK163 pKa = 10.09KK164 pKa = 9.92KK165 pKa = 9.38ATAAKK170 pKa = 9.81RR171 pKa = 11.84KK172 pKa = 9.03AARR175 pKa = 11.84KK176 pKa = 7.8AKK178 pKa = 9.93KK179 pKa = 9.61VRR181 pKa = 11.84RR182 pKa = 11.84PKK184 pKa = 10.07KK185 pKa = 9.13AAPKK189 pKa = 9.77RR190 pKa = 11.84RR191 pKa = 11.84PAAKK195 pKa = 9.87KK196 pKa = 9.48AAKK199 pKa = 9.96KK200 pKa = 8.61STKK203 pKa = 9.93KK204 pKa = 10.5SPKK207 pKa = 8.6KK208 pKa = 10.02AKK210 pKa = 9.9KK211 pKa = 9.18AVKK214 pKa = 9.68RR215 pKa = 11.84RR216 pKa = 11.84PAAKK220 pKa = 8.61KK221 pKa = 7.75TRR223 pKa = 11.84RR224 pKa = 11.84SPRR227 pKa = 11.84KK228 pKa = 7.84SAKK231 pKa = 9.48ARR233 pKa = 11.84RR234 pKa = 11.84RR235 pKa = 11.84SPRR238 pKa = 11.84KK239 pKa = 9.3AKK241 pKa = 10.29KK242 pKa = 9.91

Molecular weight:
26.6 kDa
Isoelectric point according different methods:






Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

26461

7962

34423

23911872

33

24046

694.6

77.16

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.353 ± 0.012

2.317 ± 0.025

6.12 ± 0.012

6.685 ± 0.021

3.504 ± 0.01

6.631 ± 0.025

2.4 ± 0.01

4.976 ± 0.01

5.487 ± 0.023

8.151 ± 0.025

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.408 ± 0.008

4.472 ± 0.013

5.483 ± 0.017

4.429 ± 0.017

5.237 ± 0.016

8.595 ± 0.019

6.627 ± 0.041

6.305 ± 0.015

1.047 ± 0.005

2.77 ± 0.01

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski