Amino acid dipepetide frequency for Pelomonas saccharophila (Pseudomonas saccharophila)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.02AlaAla: 21.02 ± 0.191	1.323AlaCys: 1.323 ± 0.026	6.986AlaAsp: 6.986 ± 0.061	7.656AlaGlu: 7.656 ± 0.084	4.076AlaPhe: 4.076 ± 0.053	12.148AlaGly: 12.148 ± 0.123	2.669AlaHis: 2.669 ± 0.042	4.676AlaIle: 4.676 ± 0.055	3.729AlaLys: 3.729 ± 0.062	16.891AlaLeu: 16.891 ± 0.148	3.377AlaMet: 3.377 ± 0.041	2.86AlaAsn: 2.86 ± 0.051	6.831AlaPro: 6.831 ± 0.1	6.007AlaGln: 6.007 ± 0.074	10.081AlaArg: 10.081 ± 0.1	7.033AlaSer: 7.033 ± 0.09	6.251AlaThr: 6.251 ± 0.071	9.229AlaVal: 9.229 ± 0.082	2.339AlaTrp: 2.339 ± 0.043	2.495AlaTyr: 2.495 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	1.19CysAla: 1.19 ± 0.029	0.129CysCys: 0.129 ± 0.009	0.513CysAsp: 0.513 ± 0.018	0.497CysGlu: 0.497 ± 0.018	0.307CysPhe: 0.307 ± 0.013	0.948CysGly: 0.948 ± 0.028	0.246CysHis: 0.246 ± 0.013	0.343CysIle: 0.343 ± 0.015	0.21CysLys: 0.21 ± 0.01	0.776CysLeu: 0.776 ± 0.021	0.184CysMet: 0.184 ± 0.009	0.217CysAsn: 0.217 ± 0.013	0.519CysPro: 0.519 ± 0.019	0.24CysGln: 0.24 ± 0.012	0.601CysArg: 0.601 ± 0.019	0.524CysSer: 0.524 ± 0.018	0.463CysThr: 0.463 ± 0.015	0.655CysVal: 0.655 ± 0.021	0.141CysTrp: 0.141 ± 0.009	0.184CysTyr: 0.184 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.779AspAla: 7.779 ± 0.075	0.485AspCys: 0.485 ± 0.017	2.768AspAsp: 2.768 ± 0.048	3.295AspGlu: 3.295 ± 0.051	2.089AspPhe: 2.089 ± 0.04	5.134AspGly: 5.134 ± 0.059	1.075AspHis: 1.075 ± 0.026	2.252AspIle: 2.252 ± 0.039	1.566AspLys: 1.566 ± 0.03	5.442AspLeu: 5.442 ± 0.053	1.051AspMet: 1.051 ± 0.023	1.116AspAsn: 1.116 ± 0.029	2.937AspPro: 2.937 ± 0.043	1.562AspGln: 1.562 ± 0.032	3.357AspArg: 3.357 ± 0.046	2.239AspSer: 2.239 ± 0.038	2.426AspThr: 2.426 ± 0.039	3.767AspVal: 3.767 ± 0.048	1.139AspTrp: 1.139 ± 0.028	1.347AspTyr: 1.347 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	7.678GluAla: 7.678 ± 0.084	0.332GluCys: 0.332 ± 0.012	2.123GluAsp: 2.123 ± 0.038	2.077GluGlu: 2.077 ± 0.042	1.754GluPhe: 1.754 ± 0.036	3.817GluGly: 3.817 ± 0.052	1.38GluHis: 1.38 ± 0.033	2.359GluIle: 2.359 ± 0.044	1.499GluLys: 1.499 ± 0.033	6.771GluLeu: 6.771 ± 0.074	1.104GluMet: 1.104 ± 0.027	1.068GluAsn: 1.068 ± 0.026	2.768GluPro: 2.768 ± 0.05	2.57GluGln: 2.57 ± 0.04	4.972GluArg: 4.972 ± 0.07	2.243GluSer: 2.243 ± 0.038	2.222GluThr: 2.222 ± 0.035	3.872GluVal: 3.872 ± 0.058	0.657GluTrp: 0.657 ± 0.02	0.837GluTyr: 0.837 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	4.271PheAla: 4.271 ± 0.057	0.353PheCys: 0.353 ± 0.015	2.58PheAsp: 2.58 ± 0.042	2.106PheGlu: 2.106 ± 0.037	1.253PhePhe: 1.253 ± 0.028	3.444PheGly: 3.444 ± 0.049	0.709PheHis: 0.709 ± 0.022	1.372PheIle: 1.372 ± 0.03	1.163PheLys: 1.163 ± 0.031	2.666PheLeu: 2.666 ± 0.039	0.724PheMet: 0.724 ± 0.02	1.095PheAsn: 1.095 ± 0.027	1.374PhePro: 1.374 ± 0.029	1.018PheGln: 1.018 ± 0.024	1.754PheArg: 1.754 ± 0.034	2.04PheSer: 2.04 ± 0.032	1.776PheThr: 1.776 ± 0.037	2.652PheVal: 2.652 ± 0.042	0.507PheTrp: 0.507 ± 0.018	0.808PheTyr: 0.808 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	9.781GlyAla: 9.781 ± 0.109	0.939GlyCys: 0.939 ± 0.024	4.169GlyAsp: 4.169 ± 0.05	4.652GlyGlu: 4.652 ± 0.058	3.426GlyPhe: 3.426 ± 0.045	7.487GlyGly: 7.487 ± 0.096	2.082GlyHis: 2.082 ± 0.038	3.515GlyIle: 3.515 ± 0.049	2.757GlyLys: 2.757 ± 0.046	10.272GlyLeu: 10.272 ± 0.082	2.139GlyMet: 2.139 ± 0.04	2.102GlyAsn: 2.102 ± 0.051	3.347GlyPro: 3.347 ± 0.051	3.661GlyGln: 3.661 ± 0.05	6.515GlyArg: 6.515 ± 0.073	4.919GlySer: 4.919 ± 0.094	4.199GlyThr: 4.199 ± 0.088	6.451GlyVal: 6.451 ± 0.061	1.715GlyTrp: 1.715 ± 0.035	2.191GlyTyr: 2.191 ± 0.036	0.0GlyXaa: 0.0 ± 0.0
His	3.034HisAla: 3.034 ± 0.044	0.268HisCys: 0.268 ± 0.014	1.203HisAsp: 1.203 ± 0.029	1.249HisGlu: 1.249 ± 0.028	0.883HisPhe: 0.883 ± 0.022	2.175HisGly: 2.175 ± 0.036	0.655HisHis: 0.655 ± 0.024	0.818HisIle: 0.818 ± 0.022	0.498HisLys: 0.498 ± 0.017	2.296HisLeu: 2.296 ± 0.044	0.411HisMet: 0.411 ± 0.015	0.464HisAsn: 0.464 ± 0.016	1.398HisPro: 1.398 ± 0.033	0.767HisGln: 0.767 ± 0.02	1.565HisArg: 1.565 ± 0.032	0.973HisSer: 0.973 ± 0.026	0.835HisThr: 0.835 ± 0.023	1.509HisVal: 1.509 ± 0.029	0.46HisTrp: 0.46 ± 0.017	0.621HisTyr: 0.621 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	5.821IleAla: 5.821 ± 0.059	0.385IleCys: 0.385 ± 0.013	2.761IleAsp: 2.761 ± 0.04	2.763IleGlu: 2.763 ± 0.048	1.013IlePhe: 1.013 ± 0.024	3.772IleGly: 3.772 ± 0.054	0.772IleHis: 0.772 ± 0.021	1.065IleIle: 1.065 ± 0.025	1.306IleLys: 1.306 ± 0.031	2.711IleLeu: 2.711 ± 0.046	0.558IleMet: 0.558 ± 0.019	1.198IleAsn: 1.198 ± 0.029	1.744IlePro: 1.744 ± 0.034	1.229IleGln: 1.229 ± 0.027	2.269IleArg: 2.269 ± 0.035	2.135IleSer: 2.135 ± 0.039	2.091IleThr: 2.091 ± 0.038	3.126IleVal: 3.126 ± 0.047	0.428IleTrp: 0.428 ± 0.017	0.789IleTyr: 0.789 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	4.115LysAla: 4.115 ± 0.072	0.132LysCys: 0.132 ± 0.009	1.456LysAsp: 1.456 ± 0.03	1.234LysGlu: 1.234 ± 0.026	0.846LysPhe: 0.846 ± 0.025	2.227LysGly: 2.227 ± 0.047	0.605LysHis: 0.605 ± 0.021	1.18LysIle: 1.18 ± 0.029	1.124LysLys: 1.124 ± 0.035	3.492LysLeu: 3.492 ± 0.048	0.619LysMet: 0.619 ± 0.02	0.792LysAsn: 0.792 ± 0.024	2.128LysPro: 2.128 ± 0.038	1.053LysGln: 1.053 ± 0.028	2.09LysArg: 2.09 ± 0.037	1.546LysSer: 1.546 ± 0.03	1.742LysThr: 1.742 ± 0.033	2.175LysVal: 2.175 ± 0.044	0.287LysTrp: 0.287 ± 0.011	0.555LysTyr: 0.555 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	17.298LeuAla: 17.298 ± 0.149	1.003LeuCys: 1.003 ± 0.024	6.352LeuAsp: 6.352 ± 0.064	4.941LeuGlu: 4.941 ± 0.057	3.387LeuPhe: 3.387 ± 0.05	9.392LeuGly: 9.392 ± 0.075	2.454LeuHis: 2.454 ± 0.036	4.106LeuIle: 4.106 ± 0.053	3.793LeuLys: 3.793 ± 0.05	12.735LeuLeu: 12.735 ± 0.12	2.482LeuMet: 2.482 ± 0.044	2.781LeuAsn: 2.781 ± 0.038	6.847LeuPro: 6.847 ± 0.073	4.647LeuGln: 4.647 ± 0.057	8.864LeuArg: 8.864 ± 0.086	6.258LeuSer: 6.258 ± 0.063	5.567LeuThr: 5.567 ± 0.072	7.837LeuVal: 7.837 ± 0.071	1.499LeuTrp: 1.499 ± 0.031	1.998LeuTyr: 1.998 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	2.84MetAla: 2.84 ± 0.041	0.136MetCys: 0.136 ± 0.008	1.053MetAsp: 1.053 ± 0.024	0.848MetGlu: 0.848 ± 0.021	0.649MetPhe: 0.649 ± 0.021	1.643MetGly: 1.643 ± 0.029	0.508MetHis: 0.508 ± 0.017	0.738MetIle: 0.738 ± 0.021	0.992MetLys: 0.992 ± 0.025	2.571MetLeu: 2.571 ± 0.04	0.446MetMet: 0.446 ± 0.019	0.805MetAsn: 0.805 ± 0.022	1.47MetPro: 1.47 ± 0.026	1.012MetGln: 1.012 ± 0.024	1.665MetArg: 1.665 ± 0.035	1.507MetSer: 1.507 ± 0.03	1.391MetThr: 1.391 ± 0.032	1.401MetVal: 1.401 ± 0.03	0.199MetTrp: 0.199 ± 0.01	0.284MetTyr: 0.284 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.139AsnAla: 3.139 ± 0.058	0.243AsnCys: 0.243 ± 0.011	1.257AsnAsp: 1.257 ± 0.027	1.127AsnGlu: 1.127 ± 0.026	0.925AsnPhe: 0.925 ± 0.026	2.262AsnGly: 2.262 ± 0.055	0.496AsnHis: 0.496 ± 0.016	1.028AsnIle: 1.028 ± 0.031	0.683AsnLys: 0.683 ± 0.021	2.562AsnLeu: 2.562 ± 0.045	0.499AsnMet: 0.499 ± 0.017	0.71AsnAsn: 0.71 ± 0.025	1.756AsnPro: 1.756 ± 0.035	0.856AsnGln: 0.856 ± 0.024	1.601AsnArg: 1.601 ± 0.028	1.152AsnSer: 1.152 ± 0.034	1.282AsnThr: 1.282 ± 0.033	1.721AsnVal: 1.721 ± 0.039	0.416AsnTrp: 0.416 ± 0.016	0.662AsnTyr: 0.662 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	8.044ProAla: 8.044 ± 0.1	0.364ProCys: 0.364 ± 0.015	3.223ProAsp: 3.223 ± 0.045	3.394ProGlu: 3.394 ± 0.045	1.673ProPhe: 1.673 ± 0.033	5.199ProGly: 5.199 ± 0.058	1.074ProHis: 1.074 ± 0.028	1.665ProIle: 1.665 ± 0.032	1.471ProLys: 1.471 ± 0.031	5.813ProLeu: 5.813 ± 0.062	1.239ProMet: 1.239 ± 0.026	1.196ProAsn: 1.196 ± 0.028	2.955ProPro: 2.955 ± 0.054	2.215ProGln: 2.215 ± 0.035	3.375ProArg: 3.375 ± 0.049	2.633ProSer: 2.633 ± 0.044	2.604ProThr: 2.604 ± 0.063	4.09ProVal: 4.09 ± 0.054	0.82ProTrp: 0.82 ± 0.02	1.053ProTyr: 1.053 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	6.342GlnAla: 6.342 ± 0.079	0.241GlnCys: 0.241 ± 0.013	1.606GlnAsp: 1.606 ± 0.032	1.405GlnGlu: 1.405 ± 0.032	1.219GlnPhe: 1.219 ± 0.027	3.175GlnGly: 3.175 ± 0.038	0.904GlnHis: 0.904 ± 0.022	1.619GlnIle: 1.619 ± 0.033	0.931GlnLys: 0.931 ± 0.024	4.867GlnLeu: 4.867 ± 0.054	0.931GlnMet: 0.931 ± 0.022	0.764GlnAsn: 0.764 ± 0.022	2.483GlnPro: 2.483 ± 0.04	1.995GlnGln: 1.995 ± 0.038	3.721GlnArg: 3.721 ± 0.048	1.859GlnSer: 1.859 ± 0.03	1.819GlnThr: 1.819 ± 0.032	2.955GlnVal: 2.955 ± 0.042	0.643GlnTrp: 0.643 ± 0.021	0.693GlnTyr: 0.693 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	8.619ArgAla: 8.619 ± 0.087	0.643ArgCys: 0.643 ± 0.023	3.831ArgAsp: 3.831 ± 0.051	4.559ArgGlu: 4.559 ± 0.059	2.88ArgPhe: 2.88 ± 0.042	5.122ArgGly: 5.122 ± 0.058	1.999ArgHis: 1.999 ± 0.041	3.282ArgIle: 3.282 ± 0.04	1.777ArgLys: 1.777 ± 0.034	9.291ArgLeu: 9.291 ± 0.092	1.838ArgMet: 1.838 ± 0.029	1.661ArgAsn: 1.661 ± 0.031	3.735ArgPro: 3.735 ± 0.047	3.001ArgGln: 3.001 ± 0.048	6.11ArgArg: 6.11 ± 0.076	3.591ArgSer: 3.591 ± 0.043	2.901ArgThr: 2.901 ± 0.044	5.42ArgVal: 5.42 ± 0.06	1.422ArgTrp: 1.422 ± 0.032	1.802ArgTyr: 1.802 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	6.535SerAla: 6.535 ± 0.088	0.469SerCys: 0.469 ± 0.017	2.455SerAsp: 2.455 ± 0.036	2.357SerGlu: 2.357 ± 0.04	2.13SerPhe: 2.13 ± 0.035	5.214SerGly: 5.214 ± 0.099	1.126SerHis: 1.126 ± 0.028	2.106SerIle: 2.106 ± 0.039	1.401SerLys: 1.401 ± 0.031	5.875SerLeu: 5.875 ± 0.065	1.15SerMet: 1.15 ± 0.024	1.327SerAsn: 1.327 ± 0.032	2.844SerPro: 2.844 ± 0.038	1.837SerGln: 1.837 ± 0.035	3.531SerArg: 3.531 ± 0.046	2.912SerSer: 2.912 ± 0.063	2.818SerThr: 2.818 ± 0.045	3.752SerVal: 3.752 ± 0.045	0.827SerTrp: 0.827 ± 0.024	1.288SerTyr: 1.288 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	6.214ThrAla: 6.214 ± 0.068	0.368ThrCys: 0.368 ± 0.016	2.329ThrAsp: 2.329 ± 0.038	2.244ThrGlu: 2.244 ± 0.041	1.282ThrPhe: 1.282 ± 0.032	4.49ThrGly: 4.49 ± 0.064	1.01ThrHis: 1.01 ± 0.029	1.616ThrIle: 1.616 ± 0.038	1.14ThrLys: 1.14 ± 0.032	6.56ThrLeu: 6.56 ± 0.098	0.917ThrMet: 0.917 ± 0.024	1.138ThrAsn: 1.138 ± 0.032	3.499ThrPro: 3.499 ± 0.059	1.871ThrGln: 1.871 ± 0.03	3.306ThrArg: 3.306 ± 0.044	2.51ThrSer: 2.51 ± 0.045	2.775ThrThr: 2.775 ± 0.058	3.869ThrVal: 3.869 ± 0.053	0.654ThrTrp: 0.654 ± 0.021	0.947ThrTyr: 0.947 ± 0.026	0.0ThrXaa: 0.0 ± 0.0
Val	9.539ValAla: 9.539 ± 0.077	0.68ValCys: 0.68 ± 0.019	4.303ValAsp: 4.303 ± 0.054	4.083ValGlu: 4.083 ± 0.052	2.526ValPhe: 2.526 ± 0.042	5.715ValGly: 5.715 ± 0.061	1.525ValHis: 1.525 ± 0.026	2.94ValIle: 2.94 ± 0.045	2.328ValLys: 2.328 ± 0.046	8.139ValLeu: 8.139 ± 0.071	1.679ValMet: 1.679 ± 0.035	2.102ValAsn: 2.102 ± 0.043	3.6ValPro: 3.6 ± 0.043	2.951ValGln: 2.951 ± 0.04	4.864ValArg: 4.864 ± 0.05	3.945ValSer: 3.945 ± 0.052	3.702ValThr: 3.702 ± 0.047	5.975ValVal: 5.975 ± 0.072	0.977ValTrp: 0.977 ± 0.027	1.553ValTyr: 1.553 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.766TrpAla: 1.766 ± 0.042	0.168TrpCys: 0.168 ± 0.009	0.68TrpAsp: 0.68 ± 0.022	0.544TrpGlu: 0.544 ± 0.017	0.524TrpPhe: 0.524 ± 0.018	1.072TrpGly: 1.072 ± 0.025	0.369TrpHis: 0.369 ± 0.015	0.579TrpIle: 0.579 ± 0.021	0.449TrpLys: 0.449 ± 0.016	2.283TrpLeu: 2.283 ± 0.043	0.435TrpMet: 0.435 ± 0.016	0.41TrpAsn: 0.41 ± 0.015	0.843TrpPro: 0.843 ± 0.025	0.885TrpGln: 0.885 ± 0.023	1.526TrpArg: 1.526 ± 0.035	0.814TrpSer: 0.814 ± 0.026	0.773TrpThr: 0.773 ± 0.021	1.113TrpVal: 1.113 ± 0.03	0.328TrpTrp: 0.328 ± 0.014	0.275TrpTyr: 0.275 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.65TyrAla: 2.65 ± 0.039	0.224TyrCys: 0.224 ± 0.012	1.177TyrAsp: 1.177 ± 0.032	1.071TyrGlu: 1.071 ± 0.025	0.823TyrPhe: 0.823 ± 0.021	1.883TyrGly: 1.883 ± 0.038	0.426TyrHis: 0.426 ± 0.015	0.676TyrIle: 0.676 ± 0.021	0.582TyrLys: 0.582 ± 0.02	2.229TyrLeu: 2.229 ± 0.031	0.375TyrMet: 0.375 ± 0.014	0.57TyrAsn: 0.57 ± 0.02	1.024TyrPro: 1.024 ± 0.024	0.797TyrGln: 0.797 ± 0.021	1.718TyrArg: 1.718 ± 0.038	1.121TyrSer: 1.121 ± 0.028	1.105TyrThr: 1.105 ± 0.032	1.553TyrVal: 1.553 ± 0.028	0.378TyrTrp: 0.378 ± 0.015	0.534TyrTyr: 0.534 ± 0.023	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5252 proteins (1753254 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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