Human papillomavirus type 26

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 5

Average proteome isoelectric point is 6.18

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|P36824|VE7_HPV26 Protein E7 OS=Human papillomavirus type 26 OX=333762 GN=E7 PE=3 SV=1
MM1 pKa = 7.58HH2 pKa = 7.33GNIINIEE9 pKa = 4.1DD10 pKa = 4.04VILDD14 pKa = 4.22LVPQPEE20 pKa = 3.99IDD22 pKa = 3.66LRR24 pKa = 11.84CYY26 pKa = 9.81EE27 pKa = 4.05QLDD30 pKa = 3.94YY31 pKa = 11.52EE32 pKa = 4.48QFDD35 pKa = 3.88SSDD38 pKa = 3.39EE39 pKa = 4.47DD40 pKa = 3.42EE41 pKa = 4.51TDD43 pKa = 3.77NMRR46 pKa = 11.84DD47 pKa = 3.31QQARR51 pKa = 11.84QAGQEE56 pKa = 3.56VCYY59 pKa = 10.28RR60 pKa = 11.84IEE62 pKa = 4.43AQCCMCNSIVQLAVQSSRR80 pKa = 11.84QNVRR84 pKa = 11.84VLEE87 pKa = 3.95QMLMEE92 pKa = 5.02DD93 pKa = 3.55VSLVCHH99 pKa = 5.63QCAAQQ104 pKa = 3.32

Molecular weight: 12.0 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P36824|VE7_HPV26 Protein E7 OS=Human papillomavirus type 26 OX=333762 GN=E7 PE=3 SV=1
MM1 pKa = 7.49FEE3 pKa = 4.8DD4 pKa = 3.41PRR6 pKa = 11.84EE7 pKa = 4.14RR8 pKa = 11.84PRR10 pKa = 11.84TLHH13 pKa = 6.11EE14 pKa = 4.38LCEE17 pKa = 4.35SLNTTLQNLQVQCVYY32 pKa = 10.77CKK34 pKa = 9.05EE35 pKa = 4.17TLQWADD41 pKa = 3.14VYY43 pKa = 11.69NFAICDD49 pKa = 3.65LRR51 pKa = 11.84VVYY54 pKa = 10.33RR55 pKa = 11.84DD56 pKa = 3.43RR57 pKa = 11.84SPYY60 pKa = 9.7AACKK64 pKa = 9.8RR65 pKa = 11.84CVIFYY70 pKa = 10.95SKK72 pKa = 8.55ITEE75 pKa = 3.89YY76 pKa = 10.58RR77 pKa = 11.84RR78 pKa = 11.84YY79 pKa = 7.26TCSVYY84 pKa = 10.75GATLEE89 pKa = 4.32ALTKK93 pKa = 10.56KK94 pKa = 10.39SLCNLLIRR102 pKa = 11.84CHH104 pKa = 6.32RR105 pKa = 11.84CQMPLGPEE113 pKa = 3.82EE114 pKa = 4.01KK115 pKa = 10.18QRR117 pKa = 11.84IVDD120 pKa = 3.56EE121 pKa = 4.01KK122 pKa = 11.17RR123 pKa = 11.84RR124 pKa = 11.84FHH126 pKa = 7.19EE127 pKa = 5.57IAGQWKK133 pKa = 9.3GLCTNCWRR141 pKa = 11.84PRR143 pKa = 11.84RR144 pKa = 11.84QTEE147 pKa = 4.11TQVV150 pKa = 2.78

Molecular weight: 17.92 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

2242

104

638

373.7

41.9

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.709 ± 0.271

3.078 ± 0.972

5.665 ± 0.58

4.862 ± 0.646

3.791 ± 0.482

5.709 ± 0.809

2.186 ± 0.145

5.843 ± 0.667

5.219 ± 0.87

7.27 ± 0.676

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.65 ± 0.259

4.46 ± 0.637

5.798 ± 1.656

5.263 ± 0.978

4.505 ± 0.831

7.939 ± 0.888

8.921 ± 1.231

6.289 ± 0.485

1.427 ± 0.281

4.416 ± 0.397
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski