Amino acid dipepetide frequency for Giraffa camelopardalis papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.129AlaAla: 9.129 ± 1.46
2.49AlaCys: 2.49 ± 1.273
6.224AlaAsp: 6.224 ± 0.887
4.564AlaGlu: 4.564 ± 0.641
1.66AlaPhe: 1.66 ± 0.869
5.809AlaGly: 5.809 ± 1.4
1.245AlaHis: 1.245 ± 0.659
1.66AlaIle: 1.66 ± 0.766
4.979AlaLys: 4.979 ± 1.655
6.639AlaLeu: 6.639 ± 1.199
0.415AlaMet: 0.415 ± 0.296
2.075AlaAsn: 2.075 ± 0.573
4.979AlaPro: 4.979 ± 1.413
3.32AlaGln: 3.32 ± 0.8
4.979AlaArg: 4.979 ± 1.48
4.149AlaSer: 4.149 ± 1.033
3.734AlaThr: 3.734 ± 0.662
3.32AlaVal: 3.32 ± 1.686
0.0AlaTrp: 0.0 ± 0.0
2.075AlaTyr: 2.075 ± 0.905
0.0AlaXaa: 0.0 ± 0.0
Cys
0.83CysAla: 0.83 ± 0.593
0.415CysCys: 0.415 ± 0.361
0.415CysAsp: 0.415 ± 0.296
1.245CysGlu: 1.245 ± 0.605
0.415CysPhe: 0.415 ± 0.361
2.075CysGly: 2.075 ± 1.355
0.415CysHis: 0.415 ± 0.296
0.83CysIle: 0.83 ± 0.593
1.245CysLys: 1.245 ± 0.689
3.32CysLeu: 3.32 ± 1.385
0.415CysMet: 0.415 ± 0.296
1.66CysAsn: 1.66 ± 0.865
3.32CysPro: 3.32 ± 1.625
0.0CysGln: 0.0 ± 0.0
2.075CysArg: 2.075 ± 1.408
2.905CysSer: 2.905 ± 1.295
1.66CysThr: 1.66 ± 0.876
2.49CysVal: 2.49 ± 0.908
0.83CysTrp: 0.83 ± 0.388
0.415CysTyr: 0.415 ± 0.619
0.0CysXaa: 0.0 ± 0.0
Asp
6.639AspAla: 6.639 ± 1.494
1.245AspCys: 1.245 ± 0.889
2.905AspAsp: 2.905 ± 0.636
3.32AspGlu: 3.32 ± 0.863
1.66AspPhe: 1.66 ± 0.48
2.905AspGly: 2.905 ± 0.788
0.83AspHis: 0.83 ± 0.473
2.075AspIle: 2.075 ± 1.366
2.49AspLys: 2.49 ± 0.861
3.734AspLeu: 3.734 ± 0.849
1.245AspMet: 1.245 ± 0.604
3.734AspAsn: 3.734 ± 0.818
3.32AspPro: 3.32 ± 0.824
1.245AspGln: 1.245 ± 0.66
0.83AspArg: 0.83 ± 0.593
4.564AspSer: 4.564 ± 1.112
4.564AspThr: 4.564 ± 2.291
2.49AspVal: 2.49 ± 0.923
0.415AspTrp: 0.415 ± 0.296
1.66AspTyr: 1.66 ± 0.616
0.0AspXaa: 0.0 ± 0.0
Glu
4.149GluAla: 4.149 ± 1.475
1.66GluCys: 1.66 ± 0.882
4.564GluAsp: 4.564 ± 0.683
4.149GluGlu: 4.149 ± 0.975
1.245GluPhe: 1.245 ± 0.87
4.149GluGly: 4.149 ± 1.873
0.0GluHis: 0.0 ± 0.0
0.83GluIle: 0.83 ± 0.668
2.49GluLys: 2.49 ± 1.403
5.394GluLeu: 5.394 ± 0.979
1.245GluMet: 1.245 ± 1.054
4.979GluAsn: 4.979 ± 1.491
2.075GluPro: 2.075 ± 0.785
1.66GluGln: 1.66 ± 0.535
2.49GluArg: 2.49 ± 1.263
1.66GluSer: 1.66 ± 0.589
7.054GluThr: 7.054 ± 1.441
3.734GluVal: 3.734 ± 1.228
0.415GluTrp: 0.415 ± 0.57
2.075GluTyr: 2.075 ± 0.845
0.0GluXaa: 0.0 ± 0.0
Phe
3.32PheAla: 3.32 ± 0.683
0.0PheCys: 0.0 ± 0.0
2.49PheAsp: 2.49 ± 0.823
1.245PheGlu: 1.245 ± 0.659
2.49PhePhe: 2.49 ± 0.794
3.32PheGly: 3.32 ± 0.581
0.83PheHis: 0.83 ± 0.362
2.905PheIle: 2.905 ± 0.858
1.66PheLys: 1.66 ± 0.571
3.32PheLeu: 3.32 ± 1.108
0.83PheMet: 0.83 ± 0.401
1.66PheAsn: 1.66 ± 0.927
1.245PhePro: 1.245 ± 0.32
1.245PheGln: 1.245 ± 0.556
2.49PheArg: 2.49 ± 1.263
1.66PheSer: 1.66 ± 0.291
1.245PheThr: 1.245 ± 0.66
2.905PheVal: 2.905 ± 0.947
2.075PheTrp: 2.075 ± 0.713
1.66PheTyr: 1.66 ± 0.776
0.0PheXaa: 0.0 ± 0.0
Gly
5.394GlyAla: 5.394 ± 1.962
2.905GlyCys: 2.905 ± 0.908
4.149GlyAsp: 4.149 ± 1.052
4.564GlyGlu: 4.564 ± 1.047
1.245GlyPhe: 1.245 ± 0.706
8.714GlyGly: 8.714 ± 1.742
1.66GlyHis: 1.66 ± 1.061
3.32GlyIle: 3.32 ± 0.816
2.905GlyLys: 2.905 ± 1.268
4.979GlyLeu: 4.979 ± 1.269
0.83GlyMet: 0.83 ± 0.587
1.66GlyAsn: 1.66 ± 0.536
2.905GlyPro: 2.905 ± 1.291
2.905GlyGln: 2.905 ± 0.494
4.564GlyArg: 4.564 ± 1.275
7.054GlySer: 7.054 ± 1.394
4.149GlyThr: 4.149 ± 0.703
5.809GlyVal: 5.809 ± 2.468
0.415GlyTrp: 0.415 ± 0.36
1.66GlyTyr: 1.66 ± 0.699
0.0GlyXaa: 0.0 ± 0.0
His
2.49HisAla: 2.49 ± 0.65
0.0HisCys: 0.0 ± 0.0
0.415HisAsp: 0.415 ± 0.369
1.245HisGlu: 1.245 ± 0.889
0.83HisPhe: 0.83 ± 0.675
2.49HisGly: 2.49 ± 1.216
1.245HisHis: 1.245 ± 0.741
0.83HisIle: 0.83 ± 0.387
0.83HisLys: 0.83 ± 0.622
1.66HisLeu: 1.66 ± 0.578
0.415HisMet: 0.415 ± 0.271
1.245HisAsn: 1.245 ± 0.896
2.49HisPro: 2.49 ± 0.905
1.66HisGln: 1.66 ± 0.736
2.075HisArg: 2.075 ± 0.432
3.734HisSer: 3.734 ± 1.214
2.075HisThr: 2.075 ± 0.985
0.83HisVal: 0.83 ± 0.401
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.49IleAla: 2.49 ± 0.757
2.075IleCys: 2.075 ± 1.431
1.245IleAsp: 1.245 ± 0.556
2.905IleGlu: 2.905 ± 1.11
0.415IlePhe: 0.415 ± 0.57
2.49IleGly: 2.49 ± 0.732
0.83IleHis: 0.83 ± 0.388
1.66IleIle: 1.66 ± 1.13
0.83IleLys: 0.83 ± 0.556
4.149IleLeu: 4.149 ± 1.571
0.83IleMet: 0.83 ± 0.593
0.415IleAsn: 0.415 ± 0.334
2.905IlePro: 2.905 ± 1.1
0.0IleGln: 0.0 ± 0.0
1.245IleArg: 1.245 ± 1.204
3.734IleSer: 3.734 ± 1.209
2.49IleThr: 2.49 ± 1.007
1.245IleVal: 1.245 ± 0.32
0.83IleTrp: 0.83 ± 0.434
1.245IleTyr: 1.245 ± 0.777
0.0IleXaa: 0.0 ± 0.0
Lys
5.809LysAla: 5.809 ± 0.781
0.83LysCys: 0.83 ± 0.434
3.32LysAsp: 3.32 ± 0.904
0.83LysGlu: 0.83 ± 0.388
1.245LysPhe: 1.245 ± 0.889
3.734LysGly: 3.734 ± 1.068
1.66LysHis: 1.66 ± 0.766
1.66LysIle: 1.66 ± 0.725
4.149LysLys: 4.149 ± 1.733
5.809LysLeu: 5.809 ± 1.421
1.66LysMet: 1.66 ± 0.598
1.66LysAsn: 1.66 ± 0.8
0.83LysPro: 0.83 ± 0.624
2.49LysGln: 2.49 ± 0.764
5.394LysArg: 5.394 ± 1.198
3.32LysSer: 3.32 ± 2.024
2.49LysThr: 2.49 ± 0.957
2.075LysVal: 2.075 ± 1.03
0.0LysTrp: 0.0 ± 0.0
1.245LysTyr: 1.245 ± 1.204
0.0LysXaa: 0.0 ± 0.0
Leu
3.32LeuAla: 3.32 ± 0.61
2.075LeuCys: 2.075 ± 1.028
4.564LeuAsp: 4.564 ± 1.066
5.394LeuGlu: 5.394 ± 1.079
4.979LeuPhe: 4.979 ± 1.627
4.564LeuGly: 4.564 ± 1.394
3.734LeuHis: 3.734 ± 1.61
4.564LeuIle: 4.564 ± 1.683
4.564LeuLys: 4.564 ± 2.117
8.299LeuLeu: 8.299 ± 3.255
1.66LeuMet: 1.66 ± 1.287
1.66LeuAsn: 1.66 ± 0.589
3.734LeuPro: 3.734 ± 1.465
6.224LeuGln: 6.224 ± 0.809
5.809LeuArg: 5.809 ± 1.582
7.054LeuSer: 7.054 ± 1.127
4.149LeuThr: 4.149 ± 1.268
4.979LeuVal: 4.979 ± 1.305
1.245LeuTrp: 1.245 ± 0.66
4.979LeuTyr: 4.979 ± 0.739
0.0LeuXaa: 0.0 ± 0.0
Met
2.075MetAla: 2.075 ± 0.818
0.0MetCys: 0.0 ± 0.0
0.83MetAsp: 0.83 ± 0.388
0.415MetGlu: 0.415 ± 0.361
1.66MetPhe: 1.66 ± 0.818
0.83MetGly: 0.83 ± 0.593
0.415MetHis: 0.415 ± 0.57
0.0MetIle: 0.0 ± 0.0
1.245MetLys: 1.245 ± 0.605
2.075MetLeu: 2.075 ± 0.93
0.83MetMet: 0.83 ± 0.434
0.415MetAsn: 0.415 ± 0.334
0.415MetPro: 0.415 ± 0.296
0.415MetGln: 0.415 ± 0.361
0.415MetArg: 0.415 ± 0.361
2.075MetSer: 2.075 ± 1.143
1.245MetThr: 1.245 ± 0.604
1.66MetVal: 1.66 ± 0.816
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.075AsnAla: 2.075 ± 0.812
0.415AsnCys: 0.415 ± 0.296
0.83AsnAsp: 0.83 ± 0.387
4.149AsnGlu: 4.149 ± 2.612
0.415AsnPhe: 0.415 ± 0.334
2.075AsnGly: 2.075 ± 0.475
2.075AsnHis: 2.075 ± 1.15
0.415AsnIle: 0.415 ± 0.296
1.245AsnLys: 1.245 ± 1.002
3.734AsnLeu: 3.734 ± 1.035
0.0AsnMet: 0.0 ± 0.0
1.245AsnAsn: 1.245 ± 0.66
1.66AsnPro: 1.66 ± 0.56
2.905AsnGln: 2.905 ± 0.749
2.075AsnArg: 2.075 ± 1.03
1.245AsnSer: 1.245 ± 0.889
2.075AsnThr: 2.075 ± 1.075
6.224AsnVal: 6.224 ± 0.749
0.83AsnTrp: 0.83 ± 0.362
0.415AsnTyr: 0.415 ± 0.334
0.0AsnXaa: 0.0 ± 0.0
Pro
5.394ProAla: 5.394 ± 1.146
0.415ProCys: 0.415 ± 0.334
4.149ProAsp: 4.149 ± 1.654
4.149ProGlu: 4.149 ± 0.822
1.245ProPhe: 1.245 ± 0.604
1.245ProGly: 1.245 ± 0.892
0.83ProHis: 0.83 ± 0.473
0.83ProIle: 0.83 ± 0.675
3.734ProLys: 3.734 ± 0.927
7.884ProLeu: 7.884 ± 1.241
0.0ProMet: 0.0 ± 0.0
1.66ProAsn: 1.66 ± 0.842
6.224ProPro: 6.224 ± 1.308
2.075ProGln: 2.075 ± 1.027
4.564ProArg: 4.564 ± 2.976
7.054ProSer: 7.054 ± 1.913
4.979ProThr: 4.979 ± 1.316
5.394ProVal: 5.394 ± 1.416
0.415ProTrp: 0.415 ± 0.361
2.075ProTyr: 2.075 ± 0.784
0.0ProXaa: 0.0 ± 0.0
Gln
2.49GlnAla: 2.49 ± 0.993
0.0GlnCys: 0.0 ± 0.0
0.83GlnAsp: 0.83 ± 0.622
2.49GlnGlu: 2.49 ± 0.74
1.245GlnPhe: 1.245 ± 1.002
5.394GlnGly: 5.394 ± 1.007
0.83GlnHis: 0.83 ± 0.387
1.66GlnIle: 1.66 ± 0.776
1.66GlnLys: 1.66 ± 0.736
2.49GlnLeu: 2.49 ± 0.823
2.075GlnMet: 2.075 ± 1.086
1.245GlnAsn: 1.245 ± 0.889
4.979GlnPro: 4.979 ± 1.499
3.734GlnGln: 3.734 ± 1.084
1.66GlnArg: 1.66 ± 0.634
1.66GlnSer: 1.66 ± 0.291
3.734GlnThr: 3.734 ± 0.855
4.149GlnVal: 4.149 ± 1.094
1.245GlnTrp: 1.245 ± 0.889
1.66GlnTyr: 1.66 ± 0.616
0.0GlnXaa: 0.0 ± 0.0
Arg
4.149ArgAla: 4.149 ± 0.947
3.32ArgCys: 3.32 ± 1.849
1.245ArgAsp: 1.245 ± 0.853
1.66ArgGlu: 1.66 ± 0.682
2.49ArgPhe: 2.49 ± 1.196
7.054ArgGly: 7.054 ± 1.927
2.905ArgHis: 2.905 ± 1.827
1.66ArgIle: 1.66 ± 0.758
6.224ArgLys: 6.224 ± 1.146
3.734ArgLeu: 3.734 ± 0.94
0.415ArgMet: 0.415 ± 0.521
2.49ArgAsn: 2.49 ± 0.497
4.564ArgPro: 4.564 ± 1.898
0.83ArgGln: 0.83 ± 0.434
3.734ArgArg: 3.734 ± 1.034
2.905ArgSer: 2.905 ± 1.089
4.149ArgThr: 4.149 ± 1.784
3.32ArgVal: 3.32 ± 0.582
0.83ArgTrp: 0.83 ± 0.581
2.075ArgTyr: 2.075 ± 0.97
0.0ArgXaa: 0.0 ± 0.0
Ser
5.394SerAla: 5.394 ± 1.453
3.32SerCys: 3.32 ± 2.21
2.49SerAsp: 2.49 ± 0.84
2.49SerGlu: 2.49 ± 0.745
2.905SerPhe: 2.905 ± 1.24
3.734SerGly: 3.734 ± 1.02
2.075SerHis: 2.075 ± 0.93
2.49SerIle: 2.49 ± 1.446
2.075SerLys: 2.075 ± 0.89
5.809SerLeu: 5.809 ± 1.337
1.66SerMet: 1.66 ± 0.686
4.564SerAsn: 4.564 ± 1.055
5.809SerPro: 5.809 ± 1.572
3.734SerGln: 3.734 ± 1.238
5.809SerArg: 5.809 ± 0.971
7.884SerSer: 7.884 ± 3.457
5.809SerThr: 5.809 ± 2.049
5.394SerVal: 5.394 ± 1.001
1.245SerTrp: 1.245 ± 0.703
2.905SerTyr: 2.905 ± 0.611
0.0SerXaa: 0.0 ± 0.0
Thr
3.32ThrAla: 3.32 ± 1.795
1.66ThrCys: 1.66 ± 0.725
3.734ThrAsp: 3.734 ± 1.121
4.979ThrGlu: 4.979 ± 1.168
4.149ThrPhe: 4.149 ± 0.937
4.564ThrGly: 4.564 ± 1.568
0.83ThrHis: 0.83 ± 0.599
3.32ThrIle: 3.32 ± 0.691
2.075ThrLys: 2.075 ± 1.032
2.905ThrLeu: 2.905 ± 1.652
1.245ThrMet: 1.245 ± 0.605
1.245ThrAsn: 1.245 ± 0.861
5.394ThrPro: 5.394 ± 1.821
4.149ThrGln: 4.149 ± 1.511
3.734ThrArg: 3.734 ± 0.867
4.564ThrSer: 4.564 ± 1.55
2.905ThrThr: 2.905 ± 0.762
9.544ThrVal: 9.544 ± 1.908
1.245ThrTrp: 1.245 ± 0.777
1.245ThrTyr: 1.245 ± 0.66
0.0ThrXaa: 0.0 ± 0.0
Val
3.32ValAla: 3.32 ± 1.394
2.49ValCys: 2.49 ± 0.854
4.979ValAsp: 4.979 ± 1.241
2.905ValGlu: 2.905 ± 0.828
5.809ValPhe: 5.809 ± 1.167
4.149ValGly: 4.149 ± 1.476
2.075ValHis: 2.075 ± 1.201
2.075ValIle: 2.075 ± 1.472
4.564ValLys: 4.564 ± 0.782
5.809ValLeu: 5.809 ± 1.132
1.245ValMet: 1.245 ± 0.655
0.83ValAsn: 0.83 ± 0.388
6.224ValPro: 6.224 ± 1.756
3.734ValGln: 3.734 ± 0.913
3.32ValArg: 3.32 ± 1.126
5.809ValSer: 5.809 ± 1.861
4.979ValThr: 4.979 ± 0.917
2.075ValVal: 2.075 ± 0.502
1.66ValTrp: 1.66 ± 0.671
2.075ValTyr: 2.075 ± 1.178
0.0ValXaa: 0.0 ± 0.0
Trp
0.415TrpAla: 0.415 ± 0.296
0.415TrpCys: 0.415 ± 0.619
0.83TrpAsp: 0.83 ± 0.637
1.66TrpGlu: 1.66 ± 1.061
0.83TrpPhe: 0.83 ± 0.72
1.66TrpGly: 1.66 ± 0.636
0.415TrpHis: 0.415 ± 0.496
0.415TrpIle: 0.415 ± 0.296
0.415TrpLys: 0.415 ± 0.296
0.83TrpLeu: 0.83 ± 0.593
0.0TrpMet: 0.0 ± 0.0
1.245TrpAsn: 1.245 ± 0.32
0.0TrpPro: 0.0 ± 0.0
0.83TrpGln: 0.83 ± 0.473
0.0TrpArg: 0.0 ± 0.0
2.075TrpSer: 2.075 ± 0.792
1.245TrpThr: 1.245 ± 0.576
1.66TrpVal: 1.66 ± 0.571
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.245TyrAla: 1.245 ± 0.598
1.245TyrCys: 1.245 ± 0.632
1.245TyrAsp: 1.245 ± 0.412
1.66TyrGlu: 1.66 ± 0.536
1.66TyrPhe: 1.66 ± 0.48
1.245TyrGly: 1.245 ± 0.608
1.66TyrHis: 1.66 ± 0.987
0.83TyrIle: 0.83 ± 0.388
0.83TyrLys: 0.83 ± 0.694
4.979TyrLeu: 4.979 ± 1.646
0.0TyrMet: 0.0 ± 0.0
0.415TyrAsn: 0.415 ± 0.361
1.245TyrPro: 1.245 ± 1.002
2.075TyrGln: 2.075 ± 0.711
2.49TyrArg: 2.49 ± 1.409
2.49TyrSer: 2.49 ± 1.178
2.075TyrThr: 2.075 ± 0.756
0.83TyrVal: 0.83 ± 0.387
1.245TyrTrp: 1.245 ± 0.685
1.66TyrTyr: 1.66 ± 0.878
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (2411 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski