Amino acid dipepetide frequency for Circular ssDNA virus sp.

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.196AlaAla: 4.196 ± 3.504
0.0AlaCys: 0.0 ± 0.0
5.594AlaAsp: 5.594 ± 1.576
4.196AlaGlu: 4.196 ± 3.082
0.0AlaPhe: 0.0 ± 0.0
8.392AlaGly: 8.392 ± 3.708
1.399AlaHis: 1.399 ± 0.915
2.797AlaIle: 2.797 ± 0.909
4.196AlaLys: 4.196 ± 2.745
1.399AlaLeu: 1.399 ± 1.168
4.196AlaMet: 4.196 ± 0.971
4.196AlaAsn: 4.196 ± 0.971
4.196AlaPro: 4.196 ± 1.883
4.196AlaGln: 4.196 ± 1.883
5.594AlaArg: 5.594 ± 0.578
6.993AlaSer: 6.993 ± 0.707
0.0AlaThr: 0.0 ± 0.0
2.797AlaVal: 2.797 ± 2.336
0.0AlaTrp: 0.0 ± 0.0
2.797AlaTyr: 2.797 ± 1.796
0.0AlaXaa: 0.0 ± 0.0
Cys
1.399CysAla: 1.399 ± 0.915
0.0CysCys: 0.0 ± 0.0
2.797CysAsp: 2.797 ± 1.459
1.399CysGlu: 1.399 ± 0.915
0.0CysPhe: 0.0 ± 0.0
4.196CysGly: 4.196 ± 3.082
0.0CysHis: 0.0 ± 0.0
1.399CysIle: 1.399 ± 0.915
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
1.399CysMet: 1.399 ± 0.915
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
4.196CysArg: 4.196 ± 0.971
1.399CysSer: 1.399 ± 1.743
1.399CysThr: 1.399 ± 1.168
2.797CysVal: 2.797 ± 1.459
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.797AspAla: 2.797 ± 3.486
1.399AspCys: 1.399 ± 0.915
2.797AspAsp: 2.797 ± 1.83
11.189AspGlu: 11.189 ± 5.266
2.797AspPhe: 2.797 ± 1.83
8.392AspGly: 8.392 ± 1.942
1.399AspHis: 1.399 ± 1.743
0.0AspIle: 0.0 ± 0.0
0.0AspLys: 0.0 ± 0.0
5.594AspLeu: 5.594 ± 0.578
1.399AspMet: 1.399 ± 1.168
1.399AspAsn: 1.399 ± 0.915
1.399AspPro: 1.399 ± 1.743
1.399AspGln: 1.399 ± 1.168
0.0AspArg: 0.0 ± 0.0
1.399AspSer: 1.399 ± 1.168
4.196AspThr: 4.196 ± 2.478
4.196AspVal: 4.196 ± 0.971
1.399AspTrp: 1.399 ± 1.168
2.797AspTyr: 2.797 ± 0.909
0.0AspXaa: 0.0 ± 0.0
Glu
2.797GluAla: 2.797 ± 1.459
4.196GluCys: 4.196 ± 1.702
4.196GluAsp: 4.196 ± 3.082
5.594GluGlu: 5.594 ± 2.671
9.79GluPhe: 9.79 ± 2.925
5.594GluGly: 5.594 ± 2.31
2.797GluHis: 2.797 ± 1.459
1.399GluIle: 1.399 ± 0.915
2.797GluLys: 2.797 ± 1.459
2.797GluLeu: 2.797 ± 1.83
1.399GluMet: 1.399 ± 0.915
1.399GluAsn: 1.399 ± 0.915
1.399GluPro: 1.399 ± 1.743
0.0GluGln: 0.0 ± 0.0
2.797GluArg: 2.797 ± 1.459
2.797GluSer: 2.797 ± 3.486
1.399GluThr: 1.399 ± 1.168
8.392GluVal: 8.392 ± 0.439
1.399GluTrp: 1.399 ± 0.915
1.399GluTyr: 1.399 ± 0.915
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
4.196PheAsp: 4.196 ± 0.971
2.797PheGlu: 2.797 ± 1.459
4.196PhePhe: 4.196 ± 1.402
2.797PheGly: 2.797 ± 1.459
1.399PheHis: 1.399 ± 0.915
2.797PheIle: 2.797 ± 1.83
2.797PheLys: 2.797 ± 1.83
5.594PheLeu: 5.594 ± 2.998
0.0PheMet: 0.0 ± 0.0
2.797PheAsn: 2.797 ± 1.83
1.399PhePro: 1.399 ± 0.915
4.196PheGln: 4.196 ± 2.745
2.797PheArg: 2.797 ± 0.909
4.196PheSer: 4.196 ± 1.883
1.399PheThr: 1.399 ± 1.168
2.797PheVal: 2.797 ± 0.909
1.399PheTrp: 1.399 ± 0.915
1.399PheTyr: 1.399 ± 1.168
0.0PheXaa: 0.0 ± 0.0
Gly
11.189GlyAla: 11.189 ± 4.585
1.399GlyCys: 1.399 ± 0.915
4.196GlyAsp: 4.196 ± 0.971
8.392GlyGlu: 8.392 ± 1.942
1.399GlyPhe: 1.399 ± 1.168
6.993GlyGly: 6.993 ± 2.717
1.399GlyHis: 1.399 ± 0.915
1.399GlyIle: 1.399 ± 0.915
4.196GlyLys: 4.196 ± 1.702
2.797GlyLeu: 2.797 ± 1.459
2.797GlyMet: 2.797 ± 1.83
1.399GlyAsn: 1.399 ± 1.168
6.993GlyPro: 6.993 ± 1.183
4.196GlyGln: 4.196 ± 2.478
1.399GlyArg: 1.399 ± 1.743
11.189GlySer: 11.189 ± 3.152
5.594GlyThr: 5.594 ± 2.998
1.399GlyVal: 1.399 ± 1.168
0.0GlyTrp: 0.0 ± 0.0
5.594GlyTyr: 5.594 ± 1.576
0.0GlyXaa: 0.0 ± 0.0
His
1.399HisAla: 1.399 ± 0.915
1.399HisCys: 1.399 ± 1.743
0.0HisAsp: 0.0 ± 0.0
1.399HisGlu: 1.399 ± 0.915
2.797HisPhe: 2.797 ± 1.83
2.797HisGly: 2.797 ± 1.83
2.797HisHis: 2.797 ± 1.796
1.399HisIle: 1.399 ± 0.915
4.196HisLys: 4.196 ± 3.082
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
2.797HisAsn: 2.797 ± 1.83
1.399HisPro: 1.399 ± 0.915
4.196HisGln: 4.196 ± 2.745
1.399HisArg: 1.399 ± 0.915
1.399HisSer: 1.399 ± 1.168
0.0HisThr: 0.0 ± 0.0
1.399HisVal: 1.399 ± 0.915
0.0HisTrp: 0.0 ± 0.0
2.797HisTyr: 2.797 ± 1.83
0.0HisXaa: 0.0 ± 0.0
Ile
6.993IleAla: 6.993 ± 1.183
0.0IleCys: 0.0 ± 0.0
2.797IleAsp: 2.797 ± 1.459
4.196IleGlu: 4.196 ± 1.702
0.0IlePhe: 0.0 ± 0.0
4.196IleGly: 4.196 ± 2.745
2.797IleHis: 2.797 ± 1.83
2.797IleIle: 2.797 ± 1.83
0.0IleLys: 0.0 ± 0.0
2.797IleLeu: 2.797 ± 0.909
0.0IleMet: 0.0 ± 0.0
1.399IleAsn: 1.399 ± 0.915
1.399IlePro: 1.399 ± 1.168
4.196IleGln: 4.196 ± 1.883
0.0IleArg: 0.0 ± 0.0
2.797IleSer: 2.797 ± 2.336
0.0IleThr: 0.0 ± 0.0
1.399IleVal: 1.399 ± 0.915
0.0IleTrp: 0.0 ± 0.0
1.399IleTyr: 1.399 ± 0.915
0.0IleXaa: 0.0 ± 0.0
Lys
2.797LysAla: 2.797 ± 0.909
0.0LysCys: 0.0 ± 0.0
0.0LysAsp: 0.0 ± 0.0
1.399LysGlu: 1.399 ± 0.915
2.797LysPhe: 2.797 ± 0.909
4.196LysGly: 4.196 ± 1.702
4.196LysHis: 4.196 ± 2.745
2.797LysIle: 2.797 ± 1.83
8.392LysLys: 8.392 ± 1.942
5.594LysLeu: 5.594 ± 5.018
1.399LysMet: 1.399 ± 1.295
0.0LysAsn: 0.0 ± 0.0
5.594LysPro: 5.594 ± 1.819
1.399LysGln: 1.399 ± 0.915
2.797LysArg: 2.797 ± 1.459
1.399LysSer: 1.399 ± 0.915
8.392LysThr: 8.392 ± 4.378
2.797LysVal: 2.797 ± 1.83
0.0LysTrp: 0.0 ± 0.0
4.196LysTyr: 4.196 ± 1.402
0.0LysXaa: 0.0 ± 0.0
Leu
2.797LeuAla: 2.797 ± 0.909
1.399LeuCys: 1.399 ± 0.915
6.993LeuAsp: 6.993 ± 3.035
2.797LeuGlu: 2.797 ± 1.459
4.196LeuPhe: 4.196 ± 2.745
2.797LeuGly: 2.797 ± 3.486
1.399LeuHis: 1.399 ± 0.915
1.399LeuIle: 1.399 ± 1.168
2.797LeuLys: 2.797 ± 2.336
5.594LeuLeu: 5.594 ± 3.66
2.797LeuMet: 2.797 ± 1.83
1.399LeuAsn: 1.399 ± 0.915
2.797LeuPro: 2.797 ± 0.909
2.797LeuGln: 2.797 ± 0.909
5.594LeuArg: 5.594 ± 2.671
5.594LeuSer: 5.594 ± 3.592
5.594LeuThr: 5.594 ± 2.671
2.797LeuVal: 2.797 ± 0.909
0.0LeuTrp: 0.0 ± 0.0
1.399LeuTyr: 1.399 ± 0.915
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
1.399MetCys: 1.399 ± 1.743
0.0MetAsp: 0.0 ± 0.0
2.797MetGlu: 2.797 ± 1.83
0.0MetPhe: 0.0 ± 0.0
2.797MetGly: 2.797 ± 2.336
1.399MetHis: 1.399 ± 0.915
1.399MetIle: 1.399 ± 0.915
2.797MetLys: 2.797 ± 1.83
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.399MetPro: 1.399 ± 0.915
0.0MetGln: 0.0 ± 0.0
2.797MetArg: 2.797 ± 1.83
4.196MetSer: 4.196 ± 0.971
2.797MetThr: 2.797 ± 1.83
4.196MetVal: 4.196 ± 1.402
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.797AsnAla: 2.797 ± 1.83
1.399AsnCys: 1.399 ± 0.915
1.399AsnAsp: 1.399 ± 0.915
1.399AsnGlu: 1.399 ± 0.915
0.0AsnPhe: 0.0 ± 0.0
1.399AsnGly: 1.399 ± 1.168
0.0AsnHis: 0.0 ± 0.0
1.399AsnIle: 1.399 ± 0.915
0.0AsnLys: 0.0 ± 0.0
1.399AsnLeu: 1.399 ± 0.915
0.0AsnMet: 0.0 ± 0.765
0.0AsnAsn: 0.0 ± 0.0
1.399AsnPro: 1.399 ± 0.915
1.399AsnGln: 1.399 ± 0.915
1.399AsnArg: 1.399 ± 0.915
4.196AsnSer: 4.196 ± 1.883
1.399AsnThr: 1.399 ± 1.168
1.399AsnVal: 1.399 ± 1.168
0.0AsnTrp: 0.0 ± 0.0
4.196AsnTyr: 4.196 ± 0.971
0.0AsnXaa: 0.0 ± 0.0
Pro
5.594ProAla: 5.594 ± 2.671
2.797ProCys: 2.797 ± 1.796
0.0ProAsp: 0.0 ± 0.0
5.594ProGlu: 5.594 ± 2.919
0.0ProPhe: 0.0 ± 0.0
4.196ProGly: 4.196 ± 1.883
1.399ProHis: 1.399 ± 0.915
1.399ProIle: 1.399 ± 1.168
5.594ProLys: 5.594 ± 2.671
5.594ProLeu: 5.594 ± 0.578
1.399ProMet: 1.399 ± 0.915
1.399ProAsn: 1.399 ± 1.168
2.797ProPro: 2.797 ± 1.83
2.797ProGln: 2.797 ± 0.909
1.399ProArg: 1.399 ± 0.915
2.797ProSer: 2.797 ± 2.336
5.594ProThr: 5.594 ± 1.819
2.797ProVal: 2.797 ± 1.83
2.797ProTrp: 2.797 ± 0.909
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.797GlnAla: 2.797 ± 2.336
0.0GlnCys: 0.0 ± 0.0
2.797GlnAsp: 2.797 ± 1.796
1.399GlnGlu: 1.399 ± 0.915
0.0GlnPhe: 0.0 ± 0.0
5.594GlnGly: 5.594 ± 1.819
1.399GlnHis: 1.399 ± 0.915
2.797GlnIle: 2.797 ± 1.83
2.797GlnLys: 2.797 ± 3.486
4.196GlnLeu: 4.196 ± 2.745
2.797GlnMet: 2.797 ± 1.83
0.0GlnAsn: 0.0 ± 0.0
2.797GlnPro: 2.797 ± 1.796
1.399GlnGln: 1.399 ± 0.915
4.196GlnArg: 4.196 ± 1.702
4.196GlnSer: 4.196 ± 1.883
5.594GlnThr: 5.594 ± 2.186
4.196GlnVal: 4.196 ± 3.504
0.0GlnTrp: 0.0 ± 0.0
1.399GlnTyr: 1.399 ± 1.743
0.0GlnXaa: 0.0 ± 0.0
Arg
1.399ArgAla: 1.399 ± 1.168
1.399ArgCys: 1.399 ± 1.743
1.399ArgAsp: 1.399 ± 0.915
2.797ArgGlu: 2.797 ± 1.83
2.797ArgPhe: 2.797 ± 0.909
2.797ArgGly: 2.797 ± 2.336
1.399ArgHis: 1.399 ± 0.915
6.993ArgIle: 6.993 ± 1.183
1.399ArgLys: 1.399 ± 0.915
6.993ArgLeu: 6.993 ± 2.186
0.0ArgMet: 0.0 ± 0.0
4.196ArgAsn: 4.196 ± 2.745
5.594ArgPro: 5.594 ± 2.671
2.797ArgGln: 2.797 ± 1.83
5.594ArgArg: 5.594 ± 2.31
4.196ArgSer: 4.196 ± 2.478
5.594ArgThr: 5.594 ± 1.576
2.797ArgVal: 2.797 ± 0.909
0.0ArgTrp: 0.0 ± 0.0
1.399ArgTyr: 1.399 ± 1.743
0.0ArgXaa: 0.0 ± 0.0
Ser
9.79SerAla: 9.79 ± 4.051
2.797SerCys: 2.797 ± 1.796
5.594SerAsp: 5.594 ± 3.433
1.399SerGlu: 1.399 ± 1.168
4.196SerPhe: 4.196 ± 1.883
5.594SerGly: 5.594 ± 0.578
1.399SerHis: 1.399 ± 0.915
1.399SerIle: 1.399 ± 1.743
2.797SerLys: 2.797 ± 0.909
2.797SerLeu: 2.797 ± 1.796
2.797SerMet: 2.797 ± 0.909
0.0SerAsn: 0.0 ± 0.0
2.797SerPro: 2.797 ± 1.796
6.993SerGln: 6.993 ± 2.738
6.993SerArg: 6.993 ± 4.489
4.196SerSer: 4.196 ± 2.478
4.196SerThr: 4.196 ± 1.883
5.594SerVal: 5.594 ± 2.998
1.399SerTrp: 1.399 ± 0.915
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
0.0ThrAla: 0.0 ± 0.0
0.0ThrCys: 0.0 ± 0.0
6.993ThrAsp: 6.993 ± 2.598
0.0ThrGlu: 0.0 ± 0.0
4.196ThrPhe: 4.196 ± 0.971
1.399ThrGly: 1.399 ± 1.168
1.399ThrHis: 1.399 ± 0.915
2.797ThrIle: 2.797 ± 2.336
5.594ThrLys: 5.594 ± 2.186
4.196ThrLeu: 4.196 ± 1.402
1.399ThrMet: 1.399 ± 0.969
5.594ThrAsn: 5.594 ± 2.998
6.993ThrPro: 6.993 ± 0.707
2.797ThrGln: 2.797 ± 3.486
4.196ThrArg: 4.196 ± 1.883
1.399ThrSer: 1.399 ± 1.168
2.797ThrThr: 2.797 ± 0.909
1.399ThrVal: 1.399 ± 1.168
2.797ThrTrp: 2.797 ± 1.459
2.797ThrTyr: 2.797 ± 1.459
0.0ThrXaa: 0.0 ± 0.0
Val
2.797ValAla: 2.797 ± 2.336
0.0ValCys: 0.0 ± 0.0
2.797ValAsp: 2.797 ± 1.796
4.196ValGlu: 4.196 ± 2.745
5.594ValPhe: 5.594 ± 1.819
6.993ValGly: 6.993 ± 4.143
4.196ValHis: 4.196 ± 1.402
0.0ValIle: 0.0 ± 0.0
1.399ValLys: 1.399 ± 0.915
2.797ValLeu: 2.797 ± 1.459
1.399ValMet: 1.399 ± 0.915
0.0ValAsn: 0.0 ± 0.0
4.196ValPro: 4.196 ± 1.883
4.196ValGln: 4.196 ± 0.971
6.993ValArg: 6.993 ± 2.179
5.594ValSer: 5.594 ± 1.819
0.0ValThr: 0.0 ± 0.0
4.196ValVal: 4.196 ± 0.971
0.0ValTrp: 0.0 ± 0.0
1.399ValTyr: 1.399 ± 1.168
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.399TrpGlu: 1.399 ± 0.915
0.0TrpPhe: 0.0 ± 0.0
1.399TrpGly: 1.399 ± 1.168
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
4.196TrpLys: 4.196 ± 1.702
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.0TrpArg: 0.0 ± 0.0
1.399TrpSer: 1.399 ± 1.168
0.0TrpThr: 0.0 ± 0.0
1.399TrpVal: 1.399 ± 0.915
1.399TrpTrp: 1.399 ± 0.915
1.399TrpTyr: 1.399 ± 0.915
0.0TrpXaa: 0.0 ± 0.0
Tyr
5.594TyrAla: 5.594 ± 1.576
2.797TyrCys: 2.797 ± 1.83
1.399TyrAsp: 1.399 ± 0.915
0.0TyrGlu: 0.0 ± 0.0
4.196TyrPhe: 4.196 ± 0.971
1.399TyrGly: 1.399 ± 1.168
1.399TyrHis: 1.399 ± 1.743
2.797TyrIle: 2.797 ± 1.796
4.196TyrLys: 4.196 ± 1.402
2.797TyrLeu: 2.797 ± 1.459
1.399TyrMet: 1.399 ± 0.915
0.0TyrAsn: 0.0 ± 0.0
1.399TyrPro: 1.399 ± 0.915
1.399TyrGln: 1.399 ± 0.915
1.399TyrArg: 1.399 ± 0.915
1.399TyrSer: 1.399 ± 1.743
2.797TyrThr: 2.797 ± 2.336
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (716 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski