Amino acid dipepetide frequency for Hubei tombus-like virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.333AlaAla: 10.333 ± 3.968
3.444AlaCys: 3.444 ± 2.948
10.333AlaAsp: 10.333 ± 0.91
4.592AlaGlu: 4.592 ± 2.305
6.889AlaPhe: 6.889 ± 1.019
4.592AlaGly: 4.592 ± 2.305
1.148AlaHis: 1.148 ± 0.643
5.741AlaIle: 5.741 ± 3.288
4.592AlaLys: 4.592 ± 0.946
4.592AlaLeu: 4.592 ± 0.946
1.148AlaMet: 1.148 ± 0.983
3.444AlaAsn: 3.444 ± 2.948
3.444AlaPro: 3.444 ± 0.303
1.148AlaGln: 1.148 ± 0.643
6.889AlaArg: 6.889 ± 2.645
4.592AlaSer: 4.592 ± 0.679
4.592AlaThr: 4.592 ± 2.305
6.889AlaVal: 6.889 ± 1.019
0.0AlaTrp: 0.0 ± 0.0
1.148AlaTyr: 1.148 ± 0.643
0.0AlaXaa: 0.0 ± 0.0
Cys
1.148CysAla: 1.148 ± 0.643
0.0CysCys: 0.0 ± 0.0
1.148CysAsp: 1.148 ± 0.983
0.0CysGlu: 0.0 ± 0.0
1.148CysPhe: 1.148 ± 0.983
0.0CysGly: 0.0 ± 0.0
1.148CysHis: 1.148 ± 0.643
2.296CysIle: 2.296 ± 1.966
0.0CysLys: 0.0 ± 0.0
3.444CysLeu: 3.444 ± 1.929
0.0CysMet: 0.0 ± 0.0
1.148CysAsn: 1.148 ± 0.643
1.148CysPro: 1.148 ± 0.643
1.148CysGln: 1.148 ± 0.643
1.148CysArg: 1.148 ± 0.643
2.296CysSer: 2.296 ± 0.34
0.0CysThr: 0.0 ± 0.0
1.148CysVal: 1.148 ± 0.643
0.0CysTrp: 0.0 ± 0.0
2.296CysTyr: 2.296 ± 1.286
0.0CysXaa: 0.0 ± 0.0
Asp
4.592AspAla: 4.592 ± 0.946
1.148AspCys: 1.148 ± 0.643
2.296AspAsp: 2.296 ± 1.286
2.296AspGlu: 2.296 ± 1.286
0.0AspPhe: 0.0 ± 0.0
3.444AspGly: 3.444 ± 1.929
1.148AspHis: 1.148 ± 0.643
3.444AspIle: 3.444 ± 1.323
1.148AspLys: 1.148 ± 0.643
2.296AspLeu: 2.296 ± 0.34
1.148AspMet: 1.148 ± 0.643
2.296AspAsn: 2.296 ± 0.34
3.444AspPro: 3.444 ± 1.929
4.592AspGln: 4.592 ± 0.679
1.148AspArg: 1.148 ± 0.643
0.0AspSer: 0.0 ± 0.0
4.592AspThr: 4.592 ± 0.946
2.296AspVal: 2.296 ± 0.34
1.148AspTrp: 1.148 ± 0.643
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
1.148GluAla: 1.148 ± 0.643
0.0GluCys: 0.0 ± 0.0
0.0GluAsp: 0.0 ± 0.0
4.592GluGlu: 4.592 ± 0.679
3.444GluPhe: 3.444 ± 1.929
1.148GluGly: 1.148 ± 0.643
1.148GluHis: 1.148 ± 0.643
3.444GluIle: 3.444 ± 0.303
3.444GluLys: 3.444 ± 1.929
8.037GluLeu: 8.037 ± 2.002
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
2.296GluPro: 2.296 ± 1.286
3.444GluGln: 3.444 ± 0.303
4.592GluArg: 4.592 ± 0.946
5.741GluSer: 5.741 ± 3.215
1.148GluThr: 1.148 ± 0.643
4.592GluVal: 4.592 ± 0.679
2.296GluTrp: 2.296 ± 0.34
3.444GluTyr: 3.444 ± 1.929
0.0GluXaa: 0.0 ± 0.0
Phe
3.444PheAla: 3.444 ± 1.323
1.148PheCys: 1.148 ± 0.643
1.148PheAsp: 1.148 ± 0.643
1.148PheGlu: 1.148 ± 0.643
0.0PhePhe: 0.0 ± 0.0
0.0PheGly: 0.0 ± 0.0
4.592PheHis: 4.592 ± 0.679
2.296PheIle: 2.296 ± 0.34
1.148PheLys: 1.148 ± 0.643
2.296PheLeu: 2.296 ± 0.34
2.296PheMet: 2.296 ± 0.34
4.592PheAsn: 4.592 ± 0.946
0.0PhePro: 0.0 ± 0.0
0.0PheGln: 0.0 ± 0.0
2.296PheArg: 2.296 ± 1.286
2.296PheSer: 2.296 ± 1.286
5.741PheThr: 5.741 ± 1.589
2.296PheVal: 2.296 ± 0.34
0.0PheTrp: 0.0 ± 0.0
3.444PheTyr: 3.444 ± 0.303
0.0PheXaa: 0.0 ± 0.0
Gly
6.889GlyAla: 6.889 ± 2.645
2.296GlyCys: 2.296 ± 1.286
3.444GlyAsp: 3.444 ± 1.929
6.889GlyGlu: 6.889 ± 0.607
3.444GlyPhe: 3.444 ± 0.303
0.0GlyGly: 0.0 ± 0.0
0.0GlyHis: 0.0 ± 0.0
4.592GlyIle: 4.592 ± 0.679
2.296GlyLys: 2.296 ± 0.34
9.185GlyLeu: 9.185 ± 0.267
0.0GlyMet: 0.0 ± 0.0
3.444GlyAsn: 3.444 ± 1.323
5.741GlyPro: 5.741 ± 0.036
2.296GlyGln: 2.296 ± 1.966
3.444GlyArg: 3.444 ± 1.929
4.592GlySer: 4.592 ± 2.305
5.741GlyThr: 5.741 ± 1.662
5.741GlyVal: 5.741 ± 0.036
0.0GlyTrp: 0.0 ± 0.0
2.296GlyTyr: 2.296 ± 1.286
0.0GlyXaa: 0.0 ± 0.0
His
1.148HisAla: 1.148 ± 0.643
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.148HisGly: 1.148 ± 0.643
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.148HisLys: 1.148 ± 0.983
2.296HisLeu: 2.296 ± 0.34
0.0HisMet: 0.0 ± 0.0
3.444HisAsn: 3.444 ± 1.323
3.444HisPro: 3.444 ± 0.303
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.148HisSer: 1.148 ± 0.643
0.0HisThr: 0.0 ± 0.0
4.592HisVal: 4.592 ± 0.946
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.296IleAla: 2.296 ± 0.34
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
4.592IleGlu: 4.592 ± 0.946
0.0IlePhe: 0.0 ± 0.0
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
1.148IleIle: 1.148 ± 0.983
3.444IleLys: 3.444 ± 0.303
2.296IleLeu: 2.296 ± 0.34
2.296IleMet: 2.296 ± 1.286
3.444IleAsn: 3.444 ± 0.303
3.444IlePro: 3.444 ± 0.303
2.296IleGln: 2.296 ± 0.34
2.296IleArg: 2.296 ± 0.34
6.889IleSer: 6.889 ± 0.607
4.592IleThr: 4.592 ± 2.305
0.0IleVal: 0.0 ± 0.0
1.148IleTrp: 1.148 ± 0.983
2.296IleTyr: 2.296 ± 1.966
0.0IleXaa: 0.0 ± 0.0
Lys
5.741LysAla: 5.741 ± 3.215
1.148LysCys: 1.148 ± 0.643
1.148LysAsp: 1.148 ± 0.643
2.296LysGlu: 2.296 ± 0.34
1.148LysPhe: 1.148 ± 0.643
2.296LysGly: 2.296 ± 1.286
0.0LysHis: 0.0 ± 0.0
1.148LysIle: 1.148 ± 0.643
4.592LysLys: 4.592 ± 0.679
4.592LysLeu: 4.592 ± 0.946
0.0LysMet: 0.0 ± 0.0
1.148LysAsn: 1.148 ± 0.643
3.444LysPro: 3.444 ± 1.323
4.592LysGln: 4.592 ± 0.679
3.444LysArg: 3.444 ± 0.303
2.296LysSer: 2.296 ± 1.966
0.0LysThr: 0.0 ± 0.0
4.592LysVal: 4.592 ± 0.946
2.296LysTrp: 2.296 ± 0.34
1.148LysTyr: 1.148 ± 0.983
0.0LysXaa: 0.0 ± 0.0
Leu
8.037LeuAla: 8.037 ± 5.254
1.148LeuCys: 1.148 ± 0.643
2.296LeuAsp: 2.296 ± 1.286
6.889LeuGlu: 6.889 ± 2.233
3.444LeuPhe: 3.444 ± 1.929
6.889LeuGly: 6.889 ± 1.019
2.296LeuHis: 2.296 ± 1.966
5.741LeuIle: 5.741 ± 3.215
1.148LeuLys: 1.148 ± 0.643
10.333LeuLeu: 10.333 ± 0.91
2.296LeuMet: 2.296 ± 0.452
3.444LeuAsn: 3.444 ± 0.303
3.444LeuPro: 3.444 ± 1.929
4.592LeuGln: 4.592 ± 0.679
2.296LeuArg: 2.296 ± 0.34
6.889LeuSer: 6.889 ± 1.019
6.889LeuThr: 6.889 ± 2.645
2.296LeuVal: 2.296 ± 1.286
0.0LeuTrp: 0.0 ± 0.0
3.444LeuTyr: 3.444 ± 1.929
0.0LeuXaa: 0.0 ± 0.0
Met
2.296MetAla: 2.296 ± 1.966
1.148MetCys: 1.148 ± 0.643
1.148MetAsp: 1.148 ± 0.643
1.148MetGlu: 1.148 ± 0.643
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.296MetLys: 2.296 ± 0.34
3.444MetLeu: 3.444 ± 1.323
0.0MetMet: 0.0 ± 0.0
1.148MetAsn: 1.148 ± 0.643
0.0MetPro: 0.0 ± 0.0
1.148MetGln: 1.148 ± 0.983
0.0MetArg: 0.0 ± 0.0
1.148MetSer: 1.148 ± 0.643
3.444MetThr: 3.444 ± 1.323
2.296MetVal: 2.296 ± 1.286
0.0MetTrp: 0.0 ± 0.0
1.148MetTyr: 1.148 ± 0.643
0.0MetXaa: 0.0 ± 0.0
Asn
6.889AsnAla: 6.889 ± 4.271
1.148AsnCys: 1.148 ± 0.643
1.148AsnAsp: 1.148 ± 0.643
1.148AsnGlu: 1.148 ± 0.643
1.148AsnPhe: 1.148 ± 0.643
3.444AsnGly: 3.444 ± 0.303
1.148AsnHis: 1.148 ± 0.983
1.148AsnIle: 1.148 ± 0.983
0.0AsnLys: 0.0 ± 0.0
3.444AsnLeu: 3.444 ± 0.303
2.296AsnMet: 2.296 ± 1.966
4.592AsnAsn: 4.592 ± 2.305
2.296AsnPro: 2.296 ± 0.34
2.296AsnGln: 2.296 ± 0.34
2.296AsnArg: 2.296 ± 1.286
4.592AsnSer: 4.592 ± 0.679
4.592AsnThr: 4.592 ± 0.679
4.592AsnVal: 4.592 ± 0.679
1.148AsnTrp: 1.148 ± 0.983
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.592ProAla: 4.592 ± 2.572
2.296ProCys: 2.296 ± 0.34
0.0ProAsp: 0.0 ± 0.0
1.148ProGlu: 1.148 ± 0.643
2.296ProPhe: 2.296 ± 1.286
6.889ProGly: 6.889 ± 2.645
0.0ProHis: 0.0 ± 0.0
2.296ProIle: 2.296 ± 0.34
5.741ProLys: 5.741 ± 0.036
2.296ProLeu: 2.296 ± 1.286
0.0ProMet: 0.0 ± 0.539
3.444ProAsn: 3.444 ± 1.323
2.296ProPro: 2.296 ± 1.286
2.296ProGln: 2.296 ± 1.286
9.185ProArg: 9.185 ± 0.267
1.148ProSer: 1.148 ± 0.983
2.296ProThr: 2.296 ± 1.286
8.037ProVal: 8.037 ± 1.25
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.592GlnAla: 4.592 ± 2.305
1.148GlnCys: 1.148 ± 0.643
0.0GlnAsp: 0.0 ± 0.0
0.0GlnGlu: 0.0 ± 0.0
0.0GlnPhe: 0.0 ± 0.0
3.444GlnGly: 3.444 ± 0.303
1.148GlnHis: 1.148 ± 0.643
0.0GlnIle: 0.0 ± 0.0
2.296GlnLys: 2.296 ± 1.286
3.444GlnLeu: 3.444 ± 1.929
2.296GlnMet: 2.296 ± 0.34
1.148GlnAsn: 1.148 ± 0.983
2.296GlnPro: 2.296 ± 1.286
1.148GlnGln: 1.148 ± 0.643
2.296GlnArg: 2.296 ± 1.286
1.148GlnSer: 1.148 ± 0.983
4.592GlnThr: 4.592 ± 2.305
3.444GlnVal: 3.444 ± 0.303
1.148GlnTrp: 1.148 ± 0.983
1.148GlnTyr: 1.148 ± 0.643
0.0GlnXaa: 0.0 ± 0.0
Arg
2.296ArgAla: 2.296 ± 0.34
1.148ArgCys: 1.148 ± 0.643
3.444ArgAsp: 3.444 ± 1.323
5.741ArgGlu: 5.741 ± 3.215
3.444ArgPhe: 3.444 ± 0.303
9.185ArgGly: 9.185 ± 1.359
2.296ArgHis: 2.296 ± 1.286
1.148ArgIle: 1.148 ± 0.643
4.592ArgLys: 4.592 ± 0.679
3.444ArgLeu: 3.444 ± 0.303
3.444ArgMet: 3.444 ± 0.303
3.444ArgAsn: 3.444 ± 0.303
1.148ArgPro: 1.148 ± 0.643
0.0ArgGln: 0.0 ± 0.0
3.444ArgArg: 3.444 ± 1.323
5.741ArgSer: 5.741 ± 1.589
2.296ArgThr: 2.296 ± 0.34
1.148ArgVal: 1.148 ± 0.643
0.0ArgTrp: 0.0 ± 0.0
1.148ArgTyr: 1.148 ± 0.643
0.0ArgXaa: 0.0 ± 0.0
Ser
5.741SerAla: 5.741 ± 1.662
0.0SerCys: 0.0 ± 0.0
4.592SerAsp: 4.592 ± 0.679
1.148SerGlu: 1.148 ± 0.643
4.592SerPhe: 4.592 ± 0.679
6.889SerGly: 6.889 ± 1.019
0.0SerHis: 0.0 ± 0.0
1.148SerIle: 1.148 ± 0.643
5.741SerLys: 5.741 ± 1.589
8.037SerLeu: 8.037 ± 2.002
0.0SerMet: 0.0 ± 0.0
1.148SerAsn: 1.148 ± 0.983
5.741SerPro: 5.741 ± 0.036
2.296SerGln: 2.296 ± 1.286
5.741SerArg: 5.741 ± 0.036
4.592SerSer: 4.592 ± 2.305
3.444SerThr: 3.444 ± 0.303
6.889SerVal: 6.889 ± 0.607
1.148SerTrp: 1.148 ± 0.643
1.148SerTyr: 1.148 ± 0.643
0.0SerXaa: 0.0 ± 0.0
Thr
8.037ThrAla: 8.037 ± 5.254
0.0ThrCys: 0.0 ± 0.0
3.444ThrAsp: 3.444 ± 0.303
2.296ThrGlu: 2.296 ± 1.286
2.296ThrPhe: 2.296 ± 0.34
9.185ThrGly: 9.185 ± 0.267
2.296ThrHis: 2.296 ± 0.34
3.444ThrIle: 3.444 ± 0.303
1.148ThrLys: 1.148 ± 0.983
4.592ThrLeu: 4.592 ± 0.679
3.444ThrMet: 3.444 ± 0.303
2.296ThrAsn: 2.296 ± 1.966
2.296ThrPro: 2.296 ± 0.34
2.296ThrGln: 2.296 ± 1.286
0.0ThrArg: 0.0 ± 0.0
4.592ThrSer: 4.592 ± 0.679
10.333ThrThr: 10.333 ± 8.845
4.592ThrVal: 4.592 ± 0.679
2.296ThrTrp: 2.296 ± 1.286
3.444ThrTyr: 3.444 ± 1.323
0.0ThrXaa: 0.0 ± 0.0
Val
6.889ValAla: 6.889 ± 0.607
2.296ValCys: 2.296 ± 0.34
3.444ValAsp: 3.444 ± 1.929
4.592ValGlu: 4.592 ± 0.946
3.444ValPhe: 3.444 ± 1.929
11.481ValGly: 11.481 ± 1.699
0.0ValHis: 0.0 ± 0.0
1.148ValIle: 1.148 ± 0.643
1.148ValLys: 1.148 ± 0.983
4.592ValLeu: 4.592 ± 0.946
0.0ValMet: 0.0 ± 0.0
1.148ValAsn: 1.148 ± 0.983
6.889ValPro: 6.889 ± 1.019
1.148ValGln: 1.148 ± 0.643
4.592ValArg: 4.592 ± 0.679
5.741ValSer: 5.741 ± 1.589
3.444ValThr: 3.444 ± 1.323
8.037ValVal: 8.037 ± 1.25
3.444ValTrp: 3.444 ± 1.929
2.296ValTyr: 2.296 ± 0.34
0.0ValXaa: 0.0 ± 0.0
Trp
1.148TrpAla: 1.148 ± 0.643
0.0TrpCys: 0.0 ± 0.0
1.148TrpAsp: 1.148 ± 0.643
2.296TrpGlu: 2.296 ± 0.34
3.444TrpPhe: 3.444 ± 1.323
2.296TrpGly: 2.296 ± 1.286
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
1.148TrpAsn: 1.148 ± 0.643
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.148TrpArg: 1.148 ± 0.643
2.296TrpSer: 2.296 ± 0.34
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
1.148TrpTrp: 1.148 ± 0.643
1.148TrpTyr: 1.148 ± 0.983
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.296TyrAla: 2.296 ± 1.966
1.148TyrCys: 1.148 ± 0.643
2.296TyrAsp: 2.296 ± 1.286
1.148TyrGlu: 1.148 ± 0.643
0.0TyrPhe: 0.0 ± 0.0
0.0TyrGly: 0.0 ± 0.0
0.0TyrHis: 0.0 ± 0.0
2.296TyrIle: 2.296 ± 0.34
1.148TyrLys: 1.148 ± 0.643
1.148TyrLeu: 1.148 ± 0.643
0.0TyrMet: 0.0 ± 0.0
3.444TyrAsn: 3.444 ± 0.303
4.592TyrPro: 4.592 ± 0.679
0.0TyrGln: 0.0 ± 0.0
2.296TyrArg: 2.296 ± 1.286
2.296TyrSer: 2.296 ± 0.34
4.592TyrThr: 4.592 ± 2.572
2.296TyrVal: 2.296 ± 0.34
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (872 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski