Amino acid dipepetide frequency for Shahe qinvirus-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.078AlaAla: 14.078 ± 6.773
1.706AlaCys: 1.706 ± 0.849
6.826AlaAsp: 6.826 ± 1.903
7.679AlaGlu: 7.679 ± 0.418
2.56AlaPhe: 2.56 ± 0.214
4.693AlaGly: 4.693 ± 2.964
1.706AlaHis: 1.706 ± 0.211
5.119AlaIle: 5.119 ± 1.692
5.973AlaLys: 5.973 ± 1.267
5.119AlaLeu: 5.119 ± 1.692
3.413AlaMet: 3.413 ± 0.421
2.986AlaAsn: 2.986 ± 0.426
2.986AlaPro: 2.986 ± 0.634
2.986AlaGln: 2.986 ± 0.426
4.693AlaArg: 4.693 ± 1.904
6.826AlaSer: 6.826 ± 0.843
3.84AlaThr: 3.84 ± 4.449
10.239AlaVal: 10.239 ± 1.264
0.853AlaTrp: 0.853 ± 0.425
3.413AlaTyr: 3.413 ± 0.638
0.0AlaXaa: 0.0 ± 0.0
Cys
0.853CysAla: 0.853 ± 0.425
0.853CysCys: 0.853 ± 0.425
1.706CysAsp: 1.706 ± 0.849
1.706CysGlu: 1.706 ± 0.849
0.427CysPhe: 0.427 ± 0.212
0.427CysGly: 0.427 ± 0.848
0.853CysHis: 0.853 ± 0.635
0.427CysIle: 0.427 ± 0.212
2.986CysLys: 2.986 ± 1.486
2.133CysLeu: 2.133 ± 1.058
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.853CysPro: 0.853 ± 0.425
0.853CysGln: 0.853 ± 0.425
0.427CysArg: 0.427 ± 0.212
0.853CysSer: 0.853 ± 0.425
0.427CysThr: 0.427 ± 0.212
1.706CysVal: 1.706 ± 0.849
0.427CysTrp: 0.427 ± 0.212
0.427CysTyr: 0.427 ± 0.212
0.0CysXaa: 0.0 ± 0.0
Asp
6.826AspAla: 6.826 ± 0.843
1.28AspCys: 1.28 ± 0.637
5.546AspAsp: 5.546 ± 1.48
4.266AspGlu: 4.266 ± 1.063
2.56AspPhe: 2.56 ± 0.214
2.986AspGly: 2.986 ± 1.486
0.427AspHis: 0.427 ± 0.212
2.986AspIle: 2.986 ± 0.634
3.413AspLys: 3.413 ± 1.698
9.386AspLeu: 9.386 ± 2.749
0.853AspMet: 0.853 ± 0.635
0.853AspAsn: 0.853 ± 0.425
4.266AspPro: 4.266 ± 1.063
2.986AspGln: 2.986 ± 0.426
2.986AspArg: 2.986 ± 0.426
3.84AspSer: 3.84 ± 1.269
2.56AspThr: 2.56 ± 1.274
5.119AspVal: 5.119 ± 0.428
0.427AspTrp: 0.427 ± 0.212
1.706AspTyr: 1.706 ± 0.849
0.0AspXaa: 0.0 ± 0.0
Glu
3.84GluAla: 3.84 ± 0.209
0.853GluCys: 0.853 ± 0.425
2.56GluAsp: 2.56 ± 1.274
4.266GluGlu: 4.266 ± 1.057
3.84GluPhe: 3.84 ± 0.851
1.706GluGly: 1.706 ± 0.849
1.28GluHis: 1.28 ± 0.637
5.973GluIle: 5.973 ± 1.912
4.693GluLys: 4.693 ± 1.275
5.119GluLeu: 5.119 ± 0.632
2.56GluMet: 2.56 ± 0.96
2.133GluAsn: 2.133 ± 1.061
2.133GluPro: 2.133 ± 0.002
0.853GluGln: 0.853 ± 0.425
2.133GluArg: 2.133 ± 1.061
4.693GluSer: 4.693 ± 1.275
2.986GluThr: 2.986 ± 0.426
4.693GluVal: 4.693 ± 0.215
0.427GluTrp: 0.427 ± 0.212
1.706GluTyr: 1.706 ± 0.211
0.0GluXaa: 0.0 ± 0.0
Phe
4.693PheAla: 4.693 ± 0.844
1.28PheCys: 1.28 ± 0.637
3.413PheAsp: 3.413 ± 0.638
2.56PheGlu: 2.56 ± 1.274
2.56PhePhe: 2.56 ± 1.274
2.133PheGly: 2.133 ± 0.002
0.427PheHis: 0.427 ± 0.212
3.84PheIle: 3.84 ± 0.851
0.853PheLys: 0.853 ± 0.425
2.56PheLeu: 2.56 ± 0.214
1.28PheMet: 1.28 ± 0.423
1.706PheAsn: 1.706 ± 2.33
1.706PhePro: 1.706 ± 0.849
1.706PheGln: 1.706 ± 0.211
1.706PheArg: 1.706 ± 0.211
3.413PheSer: 3.413 ± 0.638
2.133PheThr: 2.133 ± 1.061
2.133PheVal: 2.133 ± 1.061
0.0PheTrp: 0.0 ± 0.0
0.853PheTyr: 0.853 ± 0.635
0.0PheXaa: 0.0 ± 0.0
Gly
5.973GlyAla: 5.973 ± 3.387
0.853GlyCys: 0.853 ± 0.425
2.986GlyAsp: 2.986 ± 0.634
2.133GlyGlu: 2.133 ± 0.002
0.853GlyPhe: 0.853 ± 0.425
5.119GlyGly: 5.119 ± 3.812
0.853GlyHis: 0.853 ± 1.695
2.56GlyIle: 2.56 ± 0.214
3.84GlyLys: 3.84 ± 2.329
3.84GlyLeu: 3.84 ± 0.209
2.56GlyMet: 2.56 ± 1.274
2.133GlyAsn: 2.133 ± 1.058
1.706GlyPro: 1.706 ± 0.211
2.56GlyGln: 2.56 ± 0.846
2.56GlyArg: 2.56 ± 1.906
2.986GlySer: 2.986 ± 0.634
3.413GlyThr: 3.413 ± 1.481
4.693GlyVal: 4.693 ± 0.844
1.28GlyTrp: 1.28 ± 0.637
2.133GlyTyr: 2.133 ± 1.061
0.0GlyXaa: 0.0 ± 0.0
His
2.56HisAla: 2.56 ± 1.906
0.0HisCys: 0.0 ± 0.0
0.853HisAsp: 0.853 ± 0.425
0.0HisGlu: 0.0 ± 0.0
0.427HisPhe: 0.427 ± 0.212
0.853HisGly: 0.853 ± 0.425
0.853HisHis: 0.853 ± 0.635
2.133HisIle: 2.133 ± 2.118
0.853HisLys: 0.853 ± 0.425
2.56HisLeu: 2.56 ± 0.846
2.56HisMet: 2.56 ± 0.214
0.427HisAsn: 0.427 ± 0.212
0.853HisPro: 0.853 ± 0.425
1.28HisGln: 1.28 ± 0.423
0.853HisArg: 0.853 ± 1.695
1.706HisSer: 1.706 ± 0.849
0.427HisThr: 0.427 ± 0.212
1.706HisVal: 1.706 ± 0.211
0.427HisTrp: 0.427 ± 0.848
2.133HisTyr: 2.133 ± 0.002
0.0HisXaa: 0.0 ± 0.0
Ile
5.119IleAla: 5.119 ± 1.488
0.853IleCys: 0.853 ± 0.425
2.56IleAsp: 2.56 ± 0.214
2.986IleGlu: 2.986 ± 0.426
2.986IlePhe: 2.986 ± 1.694
2.56IleGly: 2.56 ± 1.906
1.28IleHis: 1.28 ± 0.637
1.706IleIle: 1.706 ± 0.849
4.266IleLys: 4.266 ± 0.003
5.119IleLeu: 5.119 ± 2.548
2.986IleMet: 2.986 ± 0.634
3.84IleAsn: 3.84 ± 0.209
1.28IlePro: 1.28 ± 0.637
1.28IleGln: 1.28 ± 0.637
4.266IleArg: 4.266 ± 0.003
2.986IleSer: 2.986 ± 1.486
3.84IleThr: 3.84 ± 0.209
3.84IleVal: 3.84 ± 3.389
0.0IleTrp: 0.0 ± 0.0
2.133IleTyr: 2.133 ± 1.058
0.0IleXaa: 0.0 ± 0.0
Lys
4.266LysAla: 4.266 ± 1.063
0.853LysCys: 0.853 ± 0.425
3.84LysAsp: 3.84 ± 0.209
3.84LysGlu: 3.84 ± 0.851
2.56LysPhe: 2.56 ± 1.274
4.266LysGly: 4.266 ± 2.117
2.133LysHis: 2.133 ± 1.058
4.266LysIle: 4.266 ± 1.057
3.413LysLys: 3.413 ± 0.421
5.546LysLeu: 5.546 ± 0.64
1.706LysMet: 1.706 ± 0.849
2.986LysAsn: 2.986 ± 1.486
0.853LysPro: 0.853 ± 0.425
2.133LysGln: 2.133 ± 2.118
4.693LysArg: 4.693 ± 2.335
3.84LysSer: 3.84 ± 0.851
3.84LysThr: 3.84 ± 1.911
5.119LysVal: 5.119 ± 1.488
0.0LysTrp: 0.0 ± 0.0
2.986LysTyr: 2.986 ± 0.634
0.0LysXaa: 0.0 ± 0.0
Leu
7.253LeuAla: 7.253 ± 1.69
2.56LeuCys: 2.56 ± 0.846
5.546LeuAsp: 5.546 ± 1.7
5.119LeuGlu: 5.119 ± 1.488
2.986LeuPhe: 2.986 ± 0.634
5.973LeuGly: 5.973 ± 0.208
1.706LeuHis: 1.706 ± 0.211
2.986LeuIle: 2.986 ± 0.426
5.119LeuLys: 5.119 ± 1.488
6.399LeuLeu: 6.399 ± 0.005
0.427LeuMet: 0.427 ± 0.212
4.266LeuAsn: 4.266 ± 1.063
3.84LeuPro: 3.84 ± 0.209
2.133LeuGln: 2.133 ± 0.002
4.266LeuArg: 4.266 ± 0.003
6.826LeuSer: 6.826 ± 1.903
5.546LeuThr: 5.546 ± 1.48
4.693LeuVal: 4.693 ± 0.215
1.28LeuTrp: 1.28 ± 0.637
1.28LeuTyr: 1.28 ± 0.423
0.0LeuXaa: 0.0 ± 0.0
Met
3.413MetAla: 3.413 ± 0.421
0.0MetCys: 0.0 ± 0.0
1.706MetAsp: 1.706 ± 0.849
1.28MetGlu: 1.28 ± 0.637
2.133MetPhe: 2.133 ± 0.002
1.706MetGly: 1.706 ± 0.211
0.0MetHis: 0.0 ± 0.0
0.853MetIle: 0.853 ± 1.695
2.56MetLys: 2.56 ± 1.274
2.133MetLeu: 2.133 ± 1.061
0.853MetMet: 0.853 ± 0.143
1.28MetAsn: 1.28 ± 0.423
2.56MetPro: 2.56 ± 0.214
0.0MetGln: 0.0 ± 0.0
1.28MetArg: 1.28 ± 0.637
3.413MetSer: 3.413 ± 0.638
2.986MetThr: 2.986 ± 1.694
0.427MetVal: 0.427 ± 0.212
0.427MetTrp: 0.427 ± 0.212
0.853MetTyr: 0.853 ± 0.425
0.0MetXaa: 0.0 ± 0.0
Asn
3.413AsnAla: 3.413 ± 0.421
0.0AsnCys: 0.0 ± 0.0
2.56AsnAsp: 2.56 ± 0.846
0.853AsnGlu: 0.853 ± 0.425
1.28AsnPhe: 1.28 ± 0.423
2.133AsnGly: 2.133 ± 1.058
1.706AsnHis: 1.706 ± 1.271
2.56AsnIle: 2.56 ± 1.274
2.56AsnLys: 2.56 ± 0.214
2.56AsnLeu: 2.56 ± 0.846
1.706AsnMet: 1.706 ± 0.849
0.427AsnAsn: 0.427 ± 0.212
1.706AsnPro: 1.706 ± 0.849
1.706AsnGln: 1.706 ± 0.211
3.413AsnArg: 3.413 ± 1.698
5.119AsnSer: 5.119 ± 1.488
2.986AsnThr: 2.986 ± 0.426
2.133AsnVal: 2.133 ± 0.002
1.28AsnTrp: 1.28 ± 1.483
0.427AsnTyr: 0.427 ± 0.212
0.0AsnXaa: 0.0 ± 0.0
Pro
2.56ProAla: 2.56 ± 1.906
0.853ProCys: 0.853 ± 0.425
2.56ProAsp: 2.56 ± 1.274
2.133ProGlu: 2.133 ± 1.061
1.706ProPhe: 1.706 ± 0.849
0.853ProGly: 0.853 ± 0.425
1.706ProHis: 1.706 ± 0.211
1.28ProIle: 1.28 ± 0.637
2.986ProLys: 2.986 ± 0.634
2.986ProLeu: 2.986 ± 0.426
0.0ProMet: 0.0 ± 0.0
2.986ProAsn: 2.986 ± 0.426
1.706ProPro: 1.706 ± 0.849
0.853ProGln: 0.853 ± 0.425
1.706ProArg: 1.706 ± 0.211
2.986ProSer: 2.986 ± 0.426
2.986ProThr: 2.986 ± 1.486
2.986ProVal: 2.986 ± 0.426
0.427ProTrp: 0.427 ± 0.848
2.133ProTyr: 2.133 ± 0.002
0.0ProXaa: 0.0 ± 0.0
Gln
3.84GlnAla: 3.84 ± 0.209
0.427GlnCys: 0.427 ± 0.212
1.706GlnAsp: 1.706 ± 0.849
1.706GlnGlu: 1.706 ± 1.271
0.427GlnPhe: 0.427 ± 0.848
3.413GlnGly: 3.413 ± 0.638
0.427GlnHis: 0.427 ± 0.212
1.28GlnIle: 1.28 ± 1.483
1.28GlnLys: 1.28 ± 0.423
1.706GlnLeu: 1.706 ± 0.849
0.0GlnMet: 0.0 ± 0.0
1.28GlnAsn: 1.28 ± 1.483
1.706GlnPro: 1.706 ± 0.211
1.706GlnGln: 1.706 ± 1.271
1.28GlnArg: 1.28 ± 0.423
2.133GlnSer: 2.133 ± 0.002
2.133GlnThr: 2.133 ± 1.061
3.84GlnVal: 3.84 ± 0.209
0.0GlnTrp: 0.0 ± 0.0
1.28GlnTyr: 1.28 ± 0.637
0.0GlnXaa: 0.0 ± 0.0
Arg
4.266ArgAla: 4.266 ± 2.117
0.0ArgCys: 0.0 ± 0.0
1.28ArgAsp: 1.28 ± 0.637
8.106ArgGlu: 8.106 ± 0.854
2.986ArgPhe: 2.986 ± 1.486
2.56ArgGly: 2.56 ± 0.214
1.28ArgHis: 1.28 ± 0.423
3.413ArgIle: 3.413 ± 0.638
3.84ArgLys: 3.84 ± 0.209
2.133ArgLeu: 2.133 ± 0.002
2.56ArgMet: 2.56 ± 1.274
3.84ArgAsn: 3.84 ± 0.209
2.133ArgPro: 2.133 ± 1.061
1.28ArgGln: 1.28 ± 0.637
5.119ArgArg: 5.119 ± 1.488
2.56ArgSer: 2.56 ± 0.214
1.706ArgThr: 1.706 ± 0.849
5.546ArgVal: 5.546 ± 1.48
1.28ArgTrp: 1.28 ± 0.637
1.706ArgTyr: 1.706 ± 0.849
0.0ArgXaa: 0.0 ± 0.0
Ser
6.826SerAla: 6.826 ± 2.337
1.28SerCys: 1.28 ± 0.423
5.119SerAsp: 5.119 ± 0.632
2.986SerGlu: 2.986 ± 1.486
2.133SerPhe: 2.133 ± 0.002
4.693SerGly: 4.693 ± 0.844
1.706SerHis: 1.706 ± 0.849
3.84SerIle: 3.84 ± 0.851
4.693SerLys: 4.693 ± 1.275
6.399SerLeu: 6.399 ± 2.125
2.133SerMet: 2.133 ± 1.061
3.413SerAsn: 3.413 ± 1.698
2.56SerPro: 2.56 ± 0.846
2.133SerGln: 2.133 ± 1.058
5.973SerArg: 5.973 ± 0.852
3.84SerSer: 3.84 ± 0.851
3.413SerThr: 3.413 ± 0.421
3.84SerVal: 3.84 ± 0.209
0.427SerTrp: 0.427 ± 0.212
2.986SerTyr: 2.986 ± 0.634
0.0SerXaa: 0.0 ± 0.0
Thr
3.84ThrAla: 3.84 ± 3.389
1.28ThrCys: 1.28 ± 0.637
3.413ThrAsp: 3.413 ± 0.421
1.706ThrGlu: 1.706 ± 0.211
3.413ThrPhe: 3.413 ± 0.638
3.413ThrGly: 3.413 ± 1.481
2.56ThrHis: 2.56 ± 0.214
2.56ThrIle: 2.56 ± 1.274
4.266ThrLys: 4.266 ± 1.057
5.119ThrLeu: 5.119 ± 1.692
1.28ThrMet: 1.28 ± 0.423
2.986ThrAsn: 2.986 ± 0.634
0.853ThrPro: 0.853 ± 0.635
2.133ThrGln: 2.133 ± 2.118
4.693ThrArg: 4.693 ± 1.275
3.84ThrSer: 3.84 ± 1.911
2.133ThrThr: 2.133 ± 0.002
2.986ThrVal: 2.986 ± 0.426
1.28ThrTrp: 1.28 ± 0.423
2.133ThrTyr: 2.133 ± 0.002
0.0ThrXaa: 0.0 ± 0.0
Val
9.386ValAla: 9.386 ± 1.689
2.986ValCys: 2.986 ± 0.426
5.973ValAsp: 5.973 ± 0.208
4.266ValGlu: 4.266 ± 1.063
3.84ValPhe: 3.84 ± 0.209
2.133ValGly: 2.133 ± 2.118
1.28ValHis: 1.28 ± 0.423
4.266ValIle: 4.266 ± 0.003
2.986ValLys: 2.986 ± 1.486
5.546ValLeu: 5.546 ± 0.64
1.706ValMet: 1.706 ± 0.211
2.133ValAsn: 2.133 ± 0.002
2.986ValPro: 2.986 ± 0.426
2.133ValGln: 2.133 ± 1.061
2.56ValArg: 2.56 ± 1.274
5.119ValSer: 5.119 ± 1.488
5.546ValThr: 5.546 ± 5.719
4.266ValVal: 4.266 ± 2.123
1.28ValTrp: 1.28 ± 0.637
1.706ValTyr: 1.706 ± 0.849
0.0ValXaa: 0.0 ± 0.0
Trp
1.706TrpAla: 1.706 ± 1.271
0.427TrpCys: 0.427 ± 0.212
1.28TrpAsp: 1.28 ± 0.423
0.427TrpGlu: 0.427 ± 0.212
0.0TrpPhe: 0.0 ± 0.0
0.427TrpGly: 0.427 ± 0.212
0.0TrpHis: 0.0 ± 0.0
1.28TrpIle: 1.28 ± 0.423
0.853TrpLys: 0.853 ± 0.425
0.427TrpLeu: 0.427 ± 0.212
0.0TrpMet: 0.0 ± 0.0
0.427TrpAsn: 0.427 ± 0.212
0.427TrpPro: 0.427 ± 0.212
0.0TrpGln: 0.0 ± 0.0
0.853TrpArg: 0.853 ± 0.425
1.28TrpSer: 1.28 ± 0.423
0.427TrpThr: 0.427 ± 0.212
0.427TrpVal: 0.427 ± 0.212
0.427TrpTrp: 0.427 ± 0.848
0.853TrpTyr: 0.853 ± 0.425
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.986TyrAla: 2.986 ± 1.694
0.0TyrCys: 0.0 ± 0.0
3.84TyrAsp: 3.84 ± 0.851
0.427TyrGlu: 0.427 ± 0.212
1.28TyrPhe: 1.28 ± 0.637
2.986TyrGly: 2.986 ± 1.694
1.28TyrHis: 1.28 ± 1.483
2.56TyrIle: 2.56 ± 0.214
1.706TyrLys: 1.706 ± 0.849
3.413TyrLeu: 3.413 ± 0.638
1.28TyrMet: 1.28 ± 0.423
0.427TyrAsn: 0.427 ± 0.212
1.28TyrPro: 1.28 ± 0.637
0.853TyrGln: 0.853 ± 0.425
2.133TyrArg: 2.133 ± 1.061
2.133TyrSer: 2.133 ± 1.061
2.56TyrThr: 2.56 ± 0.214
1.706TyrVal: 1.706 ± 0.849
0.0TyrTrp: 0.0 ± 0.0
0.427TyrTyr: 0.427 ± 0.212
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2345 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski