Amino acid dipepetide frequency for Changjiang tombus-like virus 22

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.272AlaAla: 8.272 ± 1.474
0.0AlaCys: 0.0 ± 0.0
4.596AlaAsp: 4.596 ± 0.388
5.515AlaGlu: 5.515 ± 0.983
7.353AlaPhe: 7.353 ± 0.879
4.596AlaGly: 4.596 ± 0.905
0.0AlaHis: 0.0 ± 0.0
2.757AlaIle: 2.757 ± 0.801
3.676AlaLys: 3.676 ± 0.207
6.434AlaLeu: 6.434 ± 0.285
0.919AlaMet: 0.919 ± 0.698
0.919AlaAsn: 0.919 ± 0.595
2.757AlaPro: 2.757 ± 1.784
0.0AlaGln: 0.0 ± 0.0
6.434AlaArg: 6.434 ± 1.577
5.515AlaSer: 5.515 ± 1.603
2.757AlaThr: 2.757 ± 0.801
7.353AlaVal: 7.353 ± 4.757
2.757AlaTrp: 2.757 ± 0.801
0.919AlaTyr: 0.919 ± 0.595
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.838CysAsp: 1.838 ± 0.103
0.919CysGlu: 0.919 ± 0.595
0.0CysPhe: 0.0 ± 0.0
1.838CysGly: 1.838 ± 0.103
0.919CysHis: 0.919 ± 0.698
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.838CysLeu: 1.838 ± 1.189
0.919CysMet: 0.919 ± 0.595
0.919CysAsn: 0.919 ± 0.698
0.919CysPro: 0.919 ± 0.698
0.0CysGln: 0.0 ± 0.0
0.919CysArg: 0.919 ± 0.595
1.838CysSer: 1.838 ± 1.189
0.919CysThr: 0.919 ± 0.698
0.919CysVal: 0.919 ± 0.698
0.0CysTrp: 0.0 ± 0.0
0.919CysTyr: 0.919 ± 0.595
0.0CysXaa: 0.0 ± 0.0
Asp
2.757AspAla: 2.757 ± 0.491
2.757AspCys: 2.757 ± 0.491
6.434AspAsp: 6.434 ± 0.285
2.757AspGlu: 2.757 ± 0.491
0.919AspPhe: 0.919 ± 0.698
5.515AspGly: 5.515 ± 1.603
1.838AspHis: 1.838 ± 1.396
2.757AspIle: 2.757 ± 0.801
0.0AspLys: 0.0 ± 0.0
10.11AspLeu: 10.11 ± 3.956
0.0AspMet: 0.0 ± 0.0
2.757AspAsn: 2.757 ± 0.491
6.434AspPro: 6.434 ± 1.008
1.838AspGln: 1.838 ± 1.189
3.676AspArg: 3.676 ± 1.086
4.596AspSer: 4.596 ± 0.905
0.919AspThr: 0.919 ± 0.698
7.353AspVal: 7.353 ± 0.413
2.757AspTrp: 2.757 ± 2.094
2.757AspTyr: 2.757 ± 0.491
0.0AspXaa: 0.0 ± 0.0
Glu
5.515GluAla: 5.515 ± 1.603
0.919GluCys: 0.919 ± 0.698
1.838GluAsp: 1.838 ± 0.103
3.676GluGlu: 3.676 ± 1.086
4.596GluPhe: 4.596 ± 0.388
2.757GluGly: 2.757 ± 0.491
1.838GluHis: 1.838 ± 0.103
6.434GluIle: 6.434 ± 0.285
1.838GluLys: 1.838 ± 0.103
4.596GluLeu: 4.596 ± 2.198
1.838GluMet: 1.838 ± 0.103
1.838GluAsn: 1.838 ± 0.103
3.676GluPro: 3.676 ± 2.379
3.676GluGln: 3.676 ± 1.086
10.11GluArg: 10.11 ± 5.249
5.515GluSer: 5.515 ± 1.603
1.838GluThr: 1.838 ± 0.103
4.596GluVal: 4.596 ± 0.388
1.838GluTrp: 1.838 ± 1.189
1.838GluTyr: 1.838 ± 1.396
0.0GluXaa: 0.0 ± 0.0
Phe
0.919PheAla: 0.919 ± 0.698
1.838PheCys: 1.838 ± 0.103
7.353PheAsp: 7.353 ± 2.999
2.757PheGlu: 2.757 ± 0.801
0.919PhePhe: 0.919 ± 0.698
5.515PheGly: 5.515 ± 0.983
0.0PheHis: 0.0 ± 0.0
1.838PheIle: 1.838 ± 0.103
3.676PheLys: 3.676 ± 1.499
2.757PheLeu: 2.757 ± 1.784
1.838PheMet: 1.838 ± 1.396
1.838PheAsn: 1.838 ± 0.103
0.919PhePro: 0.919 ± 0.698
0.919PheGln: 0.919 ± 0.698
0.0PheArg: 0.0 ± 0.0
6.434PheSer: 6.434 ± 1.008
1.838PheThr: 1.838 ± 1.396
6.434PheVal: 6.434 ± 1.008
0.919PheTrp: 0.919 ± 0.595
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
8.272GlyAla: 8.272 ± 2.767
1.838GlyCys: 1.838 ± 1.396
6.434GlyAsp: 6.434 ± 2.87
7.353GlyGlu: 7.353 ± 2.172
3.676GlyPhe: 3.676 ± 1.086
4.596GlyGly: 4.596 ± 1.681
0.919GlyHis: 0.919 ± 0.698
0.919GlyIle: 0.919 ± 0.595
3.676GlyLys: 3.676 ± 1.499
5.515GlyLeu: 5.515 ± 1.603
1.838GlyMet: 1.838 ± 0.408
2.757GlyAsn: 2.757 ± 0.491
4.596GlyPro: 4.596 ± 1.681
2.757GlyGln: 2.757 ± 0.801
5.515GlyArg: 5.515 ± 0.983
3.676GlySer: 3.676 ± 2.379
0.919GlyThr: 0.919 ± 0.595
5.515GlyVal: 5.515 ± 1.603
3.676GlyTrp: 3.676 ± 1.499
1.838GlyTyr: 1.838 ± 0.103
0.0GlyXaa: 0.0 ± 0.0
His
0.919HisAla: 0.919 ± 0.595
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
2.757HisGlu: 2.757 ± 0.801
0.919HisPhe: 0.919 ± 0.698
2.757HisGly: 2.757 ± 0.801
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.919HisLys: 0.919 ± 0.698
0.919HisLeu: 0.919 ± 0.698
2.757HisMet: 2.757 ± 2.094
0.919HisAsn: 0.919 ± 0.595
0.919HisPro: 0.919 ± 0.595
0.0HisGln: 0.0 ± 0.0
3.676HisArg: 3.676 ± 0.207
0.0HisSer: 0.0 ± 0.0
1.838HisThr: 1.838 ± 0.103
0.919HisVal: 0.919 ± 0.595
0.919HisTrp: 0.919 ± 0.595
1.838HisTyr: 1.838 ± 0.103
0.0HisXaa: 0.0 ± 0.0
Ile
2.757IleAla: 2.757 ± 1.784
0.919IleCys: 0.919 ± 0.595
3.676IleAsp: 3.676 ± 1.499
3.676IleGlu: 3.676 ± 1.499
0.919IlePhe: 0.919 ± 0.698
0.0IleGly: 0.0 ± 0.0
0.0IleHis: 0.0 ± 0.0
1.838IleIle: 1.838 ± 0.103
2.757IleLys: 2.757 ± 2.094
0.919IleLeu: 0.919 ± 0.595
0.919IleMet: 0.919 ± 0.595
1.838IleAsn: 1.838 ± 0.103
0.0IlePro: 0.0 ± 0.0
0.919IleGln: 0.919 ± 0.595
1.838IleArg: 1.838 ± 0.103
0.919IleSer: 0.919 ± 0.698
1.838IleThr: 1.838 ± 1.396
5.515IleVal: 5.515 ± 0.983
1.838IleTrp: 1.838 ± 1.189
0.919IleTyr: 0.919 ± 0.595
0.0IleXaa: 0.0 ± 0.0
Lys
1.838LysAla: 1.838 ± 1.396
0.0LysCys: 0.0 ± 0.0
0.919LysAsp: 0.919 ± 0.698
3.676LysGlu: 3.676 ± 1.499
0.0LysPhe: 0.0 ± 0.0
2.757LysGly: 2.757 ± 1.784
3.676LysHis: 3.676 ± 1.499
1.838LysIle: 1.838 ± 1.396
1.838LysLys: 1.838 ± 1.396
1.838LysLeu: 1.838 ± 0.103
0.919LysMet: 0.919 ± 0.698
3.676LysAsn: 3.676 ± 0.207
2.757LysPro: 2.757 ± 1.784
0.919LysGln: 0.919 ± 0.698
2.757LysArg: 2.757 ± 0.801
0.919LysSer: 0.919 ± 0.698
1.838LysThr: 1.838 ± 1.396
2.757LysVal: 2.757 ± 2.094
0.0LysTrp: 0.0 ± 0.0
0.919LysTyr: 0.919 ± 0.698
0.0LysXaa: 0.0 ± 0.0
Leu
7.353LeuAla: 7.353 ± 2.172
1.838LeuCys: 1.838 ± 1.189
5.515LeuAsp: 5.515 ± 0.983
5.515LeuGlu: 5.515 ± 0.31
6.434LeuPhe: 6.434 ± 2.301
10.11LeuGly: 10.11 ± 1.215
0.0LeuHis: 0.0 ± 0.0
4.596LeuIle: 4.596 ± 0.388
0.0LeuLys: 0.0 ± 0.0
7.353LeuLeu: 7.353 ± 0.413
4.596LeuMet: 4.596 ± 2.198
2.757LeuAsn: 2.757 ± 0.801
10.11LeuPro: 10.11 ± 1.371
0.919LeuGln: 0.919 ± 0.698
6.434LeuArg: 6.434 ± 2.301
4.596LeuSer: 4.596 ± 1.681
4.596LeuThr: 4.596 ± 0.388
3.676LeuVal: 3.676 ± 2.379
1.838LeuTrp: 1.838 ± 1.189
1.838LeuTyr: 1.838 ± 1.396
0.0LeuXaa: 0.0 ± 0.0
Met
1.838MetAla: 1.838 ± 0.103
0.919MetCys: 0.919 ± 0.698
1.838MetAsp: 1.838 ± 1.396
1.838MetGlu: 1.838 ± 0.103
1.838MetPhe: 1.838 ± 1.396
2.757MetGly: 2.757 ± 0.801
1.838MetHis: 1.838 ± 0.103
0.0MetIle: 0.0 ± 0.0
0.919MetLys: 0.919 ± 0.698
0.919MetLeu: 0.919 ± 0.698
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.838MetArg: 1.838 ± 1.189
3.676MetSer: 3.676 ± 0.207
0.919MetThr: 0.919 ± 0.698
2.757MetVal: 2.757 ± 0.491
0.919MetTrp: 0.919 ± 0.595
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.0AsnAla: 0.0 ± 0.0
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
0.0AsnGlu: 0.0 ± 0.0
1.838AsnPhe: 1.838 ± 0.103
3.676AsnGly: 3.676 ± 0.207
0.919AsnHis: 0.919 ± 0.595
0.0AsnIle: 0.0 ± 0.0
2.757AsnLys: 2.757 ± 0.801
3.676AsnLeu: 3.676 ± 2.792
0.0AsnMet: 0.0 ± 0.0
0.919AsnAsn: 0.919 ± 0.595
0.919AsnPro: 0.919 ± 0.595
1.838AsnGln: 1.838 ± 0.103
5.515AsnArg: 5.515 ± 0.983
3.676AsnSer: 3.676 ± 1.086
2.757AsnThr: 2.757 ± 0.491
0.0AsnVal: 0.0 ± 0.0
0.919AsnTrp: 0.919 ± 0.595
0.919AsnTyr: 0.919 ± 0.595
0.0AsnXaa: 0.0 ± 0.0
Pro
6.434ProAla: 6.434 ± 2.87
0.919ProCys: 0.919 ± 0.595
7.353ProAsp: 7.353 ± 0.413
11.949ProGlu: 11.949 ± 0.026
1.838ProPhe: 1.838 ± 1.396
3.676ProGly: 3.676 ± 1.086
0.0ProHis: 0.0 ± 0.0
2.757ProIle: 2.757 ± 0.491
0.0ProLys: 0.0 ± 0.0
5.515ProLeu: 5.515 ± 2.275
0.919ProMet: 0.919 ± 0.595
0.919ProAsn: 0.919 ± 0.595
9.191ProPro: 9.191 ± 3.361
1.838ProGln: 1.838 ± 0.103
6.434ProArg: 6.434 ± 1.577
3.676ProSer: 3.676 ± 1.499
0.919ProThr: 0.919 ± 0.698
5.515ProVal: 5.515 ± 0.983
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.919GlnAla: 0.919 ± 0.698
0.0GlnCys: 0.0 ± 0.0
0.919GlnAsp: 0.919 ± 0.595
0.919GlnGlu: 0.919 ± 0.698
0.919GlnPhe: 0.919 ± 0.698
1.838GlnGly: 1.838 ± 1.189
0.0GlnHis: 0.0 ± 0.0
1.838GlnIle: 1.838 ± 1.396
0.919GlnLys: 0.919 ± 0.595
2.757GlnLeu: 2.757 ± 0.491
0.0GlnMet: 0.0 ± 0.0
1.838GlnAsn: 1.838 ± 0.103
2.757GlnPro: 2.757 ± 0.801
0.919GlnGln: 0.919 ± 0.595
0.919GlnArg: 0.919 ± 0.698
2.757GlnSer: 2.757 ± 0.491
0.919GlnThr: 0.919 ± 0.595
0.0GlnVal: 0.0 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
0.919GlnTyr: 0.919 ± 0.698
0.0GlnXaa: 0.0 ± 0.0
Arg
7.353ArgAla: 7.353 ± 0.413
0.919ArgCys: 0.919 ± 0.595
3.676ArgAsp: 3.676 ± 1.086
6.434ArgGlu: 6.434 ± 1.577
1.838ArgPhe: 1.838 ± 0.103
6.434ArgGly: 6.434 ± 2.87
3.676ArgHis: 3.676 ± 1.499
0.919ArgIle: 0.919 ± 0.595
4.596ArgLys: 4.596 ± 0.905
8.272ArgLeu: 8.272 ± 1.474
0.919ArgMet: 0.919 ± 0.698
0.0ArgAsn: 0.0 ± 0.0
9.191ArgPro: 9.191 ± 0.517
0.0ArgGln: 0.0 ± 0.0
4.596ArgArg: 4.596 ± 1.681
2.757ArgSer: 2.757 ± 0.801
4.596ArgThr: 4.596 ± 0.905
9.191ArgVal: 9.191 ± 3.361
1.838ArgTrp: 1.838 ± 0.103
0.919ArgTyr: 0.919 ± 0.595
0.0ArgXaa: 0.0 ± 0.0
Ser
7.353SerAla: 7.353 ± 0.413
0.0SerCys: 0.0 ± 0.0
3.676SerAsp: 3.676 ± 1.086
0.919SerGlu: 0.919 ± 0.595
5.515SerPhe: 5.515 ± 1.603
5.515SerGly: 5.515 ± 1.603
2.757SerHis: 2.757 ± 0.491
2.757SerIle: 2.757 ± 1.784
1.838SerLys: 1.838 ± 1.396
8.272SerLeu: 8.272 ± 2.404
1.838SerMet: 1.838 ± 0.379
0.919SerAsn: 0.919 ± 0.698
3.676SerPro: 3.676 ± 1.086
0.919SerGln: 0.919 ± 0.595
5.515SerArg: 5.515 ± 0.983
2.757SerSer: 2.757 ± 0.801
1.838SerThr: 1.838 ± 0.103
4.596SerVal: 4.596 ± 1.681
4.596SerTrp: 4.596 ± 2.198
2.757SerTyr: 2.757 ± 2.094
0.0SerXaa: 0.0 ± 0.0
Thr
3.676ThrAla: 3.676 ± 1.086
1.838ThrCys: 1.838 ± 1.189
6.434ThrAsp: 6.434 ± 3.594
0.919ThrGlu: 0.919 ± 0.595
0.0ThrPhe: 0.0 ± 0.0
0.919ThrGly: 0.919 ± 0.595
0.919ThrHis: 0.919 ± 0.595
0.0ThrIle: 0.0 ± 0.0
0.919ThrLys: 0.919 ± 0.698
3.676ThrLeu: 3.676 ± 0.207
0.919ThrMet: 0.919 ± 0.698
0.919ThrAsn: 0.919 ± 0.698
1.838ThrPro: 1.838 ± 1.396
1.838ThrGln: 1.838 ± 1.396
5.515ThrArg: 5.515 ± 1.603
3.676ThrSer: 3.676 ± 2.792
0.0ThrThr: 0.0 ± 0.0
0.0ThrVal: 0.0 ± 0.0
0.0ThrTrp: 0.0 ± 0.0
0.919ThrTyr: 0.919 ± 0.595
0.0ThrXaa: 0.0 ± 0.0
Val
5.515ValAla: 5.515 ± 0.31
0.0ValCys: 0.0 ± 0.0
4.596ValAsp: 4.596 ± 1.681
7.353ValGlu: 7.353 ± 0.879
5.515ValPhe: 5.515 ± 0.31
7.353ValGly: 7.353 ± 2.172
0.919ValHis: 0.919 ± 0.595
1.838ValIle: 1.838 ± 0.103
2.757ValLys: 2.757 ± 0.491
7.353ValLeu: 7.353 ± 1.706
1.838ValMet: 1.838 ± 1.189
2.757ValAsn: 2.757 ± 1.784
8.272ValPro: 8.272 ± 1.474
0.919ValGln: 0.919 ± 0.595
3.676ValArg: 3.676 ± 0.207
7.353ValSer: 7.353 ± 0.879
2.757ValThr: 2.757 ± 0.801
10.11ValVal: 10.11 ± 1.215
0.919ValTrp: 0.919 ± 0.595
1.838ValTyr: 1.838 ± 0.103
0.0ValXaa: 0.0 ± 0.0
Trp
0.919TrpAla: 0.919 ± 0.698
0.0TrpCys: 0.0 ± 0.0
1.838TrpAsp: 1.838 ± 1.189
0.919TrpGlu: 0.919 ± 0.595
1.838TrpPhe: 1.838 ± 1.396
2.757TrpGly: 2.757 ± 1.784
0.919TrpHis: 0.919 ± 0.595
0.919TrpIle: 0.919 ± 0.698
1.838TrpLys: 1.838 ± 1.396
3.676TrpLeu: 3.676 ± 0.207
0.0TrpMet: 0.0 ± 0.0
1.838TrpAsn: 1.838 ± 0.103
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.919TrpArg: 0.919 ± 0.698
1.838TrpSer: 1.838 ± 0.103
0.0TrpThr: 0.0 ± 0.0
4.596TrpVal: 4.596 ± 0.388
1.838TrpTrp: 1.838 ± 0.103
0.919TrpTyr: 0.919 ± 0.595
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.919TyrAla: 0.919 ± 0.595
0.919TyrCys: 0.919 ± 0.698
0.0TyrAsp: 0.0 ± 0.0
0.919TyrGlu: 0.919 ± 0.595
1.838TyrPhe: 1.838 ± 0.103
0.919TyrGly: 0.919 ± 0.595
1.838TyrHis: 1.838 ± 0.103
0.0TyrIle: 0.0 ± 0.0
0.919TyrLys: 0.919 ± 0.595
3.676TyrLeu: 3.676 ± 1.086
0.919TyrMet: 0.919 ± 0.595
0.0TyrAsn: 0.0 ± 0.0
0.919TyrPro: 0.919 ± 0.698
1.838TyrGln: 1.838 ± 1.396
1.838TyrArg: 1.838 ± 1.396
2.757TyrSer: 2.757 ± 0.491
0.919TyrThr: 0.919 ± 0.698
1.838TyrVal: 1.838 ± 1.396
0.0TyrTrp: 0.0 ± 0.0
0.919TyrTyr: 0.919 ± 0.698
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1089 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski