Amino acid dipepetide frequency for Hubei picorna-like virus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.5AlaAla: 5.5 ± 0.0
0.647AlaCys: 0.647 ± 0.0
3.235AlaAsp: 3.235 ± 0.0
4.853AlaGlu: 4.853 ± 0.0
3.559AlaPhe: 3.559 ± 0.0
2.588AlaGly: 2.588 ± 0.0
1.618AlaHis: 1.618 ± 0.0
3.559AlaIle: 3.559 ± 0.0
1.294AlaLys: 1.294 ± 0.0
5.5AlaLeu: 5.5 ± 0.0
0.971AlaMet: 0.971 ± 0.0
3.882AlaAsn: 3.882 ± 0.0
3.559AlaPro: 3.559 ± 0.0
1.618AlaGln: 1.618 ± 0.0
4.529AlaArg: 4.529 ± 0.0
3.235AlaSer: 3.235 ± 0.0
5.823AlaThr: 5.823 ± 0.0
3.235AlaVal: 3.235 ± 0.0
0.971AlaTrp: 0.971 ± 0.0
4.529AlaTyr: 4.529 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.294CysAla: 1.294 ± 0.0
1.294CysCys: 1.294 ± 0.0
1.294CysAsp: 1.294 ± 0.0
0.971CysGlu: 0.971 ± 0.0
0.647CysPhe: 0.647 ± 0.0
1.618CysGly: 1.618 ± 0.0
0.324CysHis: 0.324 ± 0.0
0.324CysIle: 0.324 ± 0.0
0.971CysLys: 0.971 ± 0.0
1.294CysLeu: 1.294 ± 0.0
0.647CysMet: 0.647 ± 0.0
1.618CysAsn: 1.618 ± 0.0
0.324CysPro: 0.324 ± 0.0
0.324CysGln: 0.324 ± 0.0
1.941CysArg: 1.941 ± 0.0
1.294CysSer: 1.294 ± 0.0
1.294CysThr: 1.294 ± 0.0
0.971CysVal: 0.971 ± 0.0
0.647CysTrp: 0.647 ± 0.0
0.324CysTyr: 0.324 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.265AspAla: 2.265 ± 0.0
0.971AspCys: 0.971 ± 0.0
3.235AspAsp: 3.235 ± 0.0
3.882AspGlu: 3.882 ± 0.0
1.941AspPhe: 1.941 ± 0.0
2.265AspGly: 2.265 ± 0.0
0.971AspHis: 0.971 ± 0.0
4.206AspIle: 4.206 ± 0.0
1.941AspLys: 1.941 ± 0.0
5.5AspLeu: 5.5 ± 0.0
1.294AspMet: 1.294 ± 0.0
1.941AspAsn: 1.941 ± 0.0
2.912AspPro: 2.912 ± 0.0
1.618AspGln: 1.618 ± 0.0
1.618AspArg: 1.618 ± 0.0
2.588AspSer: 2.588 ± 0.0
3.235AspThr: 3.235 ± 0.0
3.559AspVal: 3.559 ± 0.0
0.324AspTrp: 0.324 ± 0.0
1.941AspTyr: 1.941 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
5.5GluAla: 5.5 ± 0.0
1.941GluCys: 1.941 ± 0.0
3.559GluAsp: 3.559 ± 0.0
4.853GluGlu: 4.853 ± 0.0
2.265GluPhe: 2.265 ± 0.0
4.206GluGly: 4.206 ± 0.0
1.294GluHis: 1.294 ± 0.0
5.176GluIle: 5.176 ± 0.0
2.588GluLys: 2.588 ± 0.0
4.529GluLeu: 4.529 ± 0.0
0.971GluMet: 0.971 ± 0.0
3.882GluAsn: 3.882 ± 0.0
3.559GluPro: 3.559 ± 0.0
1.294GluGln: 1.294 ± 0.0
4.529GluArg: 4.529 ± 0.0
3.559GluSer: 3.559 ± 0.0
4.206GluThr: 4.206 ± 0.0
4.529GluVal: 4.529 ± 0.0
0.971GluTrp: 0.971 ± 0.0
2.588GluTyr: 2.588 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.294PheAla: 1.294 ± 0.0
0.324PheCys: 0.324 ± 0.0
1.294PheAsp: 1.294 ± 0.0
2.912PheGlu: 2.912 ± 0.0
2.265PhePhe: 2.265 ± 0.0
1.618PheGly: 1.618 ± 0.0
2.588PheHis: 2.588 ± 0.0
3.559PheIle: 3.559 ± 0.0
1.618PheLys: 1.618 ± 0.0
3.235PheLeu: 3.235 ± 0.0
1.618PheMet: 1.618 ± 0.0
1.294PheAsn: 1.294 ± 0.0
1.294PhePro: 1.294 ± 0.0
0.647PheGln: 0.647 ± 0.0
2.265PheArg: 2.265 ± 0.0
1.941PheSer: 1.941 ± 0.0
4.206PheThr: 4.206 ± 0.0
4.206PheVal: 4.206 ± 0.0
0.0PheTrp: 0.0 ± 0.0
1.294PheTyr: 1.294 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.559GlyAla: 3.559 ± 0.0
1.941GlyCys: 1.941 ± 0.0
2.265GlyAsp: 2.265 ± 0.0
3.559GlyGlu: 3.559 ± 0.0
4.206GlyPhe: 4.206 ± 0.0
3.559GlyGly: 3.559 ± 0.0
0.324GlyHis: 0.324 ± 0.0
2.265GlyIle: 2.265 ± 0.0
3.559GlyLys: 3.559 ± 0.0
5.5GlyLeu: 5.5 ± 0.0
1.618GlyMet: 1.618 ± 0.0
4.206GlyAsn: 4.206 ± 0.0
3.559GlyPro: 3.559 ± 0.0
1.618GlyGln: 1.618 ± 0.0
2.912GlyArg: 2.912 ± 0.0
1.941GlySer: 1.941 ± 0.0
6.147GlyThr: 6.147 ± 0.0
4.853GlyVal: 4.853 ± 0.0
0.971GlyTrp: 0.971 ± 0.0
0.971GlyTyr: 0.971 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.294HisAla: 1.294 ± 0.0
0.324HisCys: 0.324 ± 0.0
1.941HisAsp: 1.941 ± 0.0
1.941HisGlu: 1.941 ± 0.0
0.971HisPhe: 0.971 ± 0.0
0.971HisGly: 0.971 ± 0.0
1.294HisHis: 1.294 ± 0.0
1.941HisIle: 1.941 ± 0.0
0.971HisLys: 0.971 ± 0.0
1.618HisLeu: 1.618 ± 0.0
0.0HisMet: 0.0 ± 0.0
1.294HisAsn: 1.294 ± 0.0
1.294HisPro: 1.294 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.971HisArg: 0.971 ± 0.0
1.618HisSer: 1.618 ± 0.0
0.971HisThr: 0.971 ± 0.0
1.294HisVal: 1.294 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.324HisTyr: 0.324 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.853IleAla: 4.853 ± 0.0
1.941IleCys: 1.941 ± 0.0
2.265IleAsp: 2.265 ± 0.0
3.235IleGlu: 3.235 ± 0.0
1.618IlePhe: 1.618 ± 0.0
3.882IleGly: 3.882 ± 0.0
0.647IleHis: 0.647 ± 0.0
2.265IleIle: 2.265 ± 0.0
2.588IleLys: 2.588 ± 0.0
5.823IleLeu: 5.823 ± 0.0
0.647IleMet: 0.647 ± 0.0
1.618IleAsn: 1.618 ± 0.0
2.912IlePro: 2.912 ± 0.0
1.618IleGln: 1.618 ± 0.0
3.559IleArg: 3.559 ± 0.0
4.853IleSer: 4.853 ± 0.0
7.117IleThr: 7.117 ± 0.0
5.5IleVal: 5.5 ± 0.0
0.647IleTrp: 0.647 ± 0.0
2.265IleTyr: 2.265 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.912LysAla: 2.912 ± 0.0
0.647LysCys: 0.647 ± 0.0
3.559LysAsp: 3.559 ± 0.0
3.235LysGlu: 3.235 ± 0.0
0.971LysPhe: 0.971 ± 0.0
2.912LysGly: 2.912 ± 0.0
0.324LysHis: 0.324 ± 0.0
2.588LysIle: 2.588 ± 0.0
4.853LysLys: 4.853 ± 0.0
4.853LysLeu: 4.853 ± 0.0
0.971LysMet: 0.971 ± 0.0
0.647LysAsn: 0.647 ± 0.0
3.235LysPro: 3.235 ± 0.0
0.324LysGln: 0.324 ± 0.0
2.912LysArg: 2.912 ± 0.0
3.235LysSer: 3.235 ± 0.0
2.912LysThr: 2.912 ± 0.0
1.941LysVal: 1.941 ± 0.0
0.324LysTrp: 0.324 ± 0.0
0.324LysTyr: 0.324 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.206LeuAla: 4.206 ± 0.0
1.618LeuCys: 1.618 ± 0.0
3.235LeuAsp: 3.235 ± 0.0
5.823LeuGlu: 5.823 ± 0.0
2.265LeuPhe: 2.265 ± 0.0
4.529LeuGly: 4.529 ± 0.0
1.618LeuHis: 1.618 ± 0.0
4.206LeuIle: 4.206 ± 0.0
3.882LeuLys: 3.882 ± 0.0
4.853LeuLeu: 4.853 ± 0.0
2.588LeuMet: 2.588 ± 0.0
2.265LeuAsn: 2.265 ± 0.0
8.088LeuPro: 8.088 ± 0.0
2.588LeuGln: 2.588 ± 0.0
5.5LeuArg: 5.5 ± 0.0
9.706LeuSer: 9.706 ± 0.0
6.47LeuThr: 6.47 ± 0.0
5.823LeuVal: 5.823 ± 0.0
0.647LeuTrp: 0.647 ± 0.0
1.941LeuTyr: 1.941 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.912MetAla: 2.912 ± 0.0
0.324MetCys: 0.324 ± 0.0
0.647MetAsp: 0.647 ± 0.0
0.324MetGlu: 0.324 ± 0.0
0.647MetPhe: 0.647 ± 0.0
1.294MetGly: 1.294 ± 0.0
0.0MetHis: 0.0 ± 0.0
2.265MetIle: 2.265 ± 0.0
0.324MetLys: 0.324 ± 0.0
3.559MetLeu: 3.559 ± 0.0
0.324MetMet: 0.324 ± 0.0
1.294MetAsn: 1.294 ± 0.0
1.294MetPro: 1.294 ± 0.0
0.971MetGln: 0.971 ± 0.0
0.324MetArg: 0.324 ± 0.0
3.235MetSer: 3.235 ± 0.0
1.618MetThr: 1.618 ± 0.0
2.265MetVal: 2.265 ± 0.0
0.647MetTrp: 0.647 ± 0.0
1.294MetTyr: 1.294 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.588AsnAla: 2.588 ± 0.0
0.0AsnCys: 0.0 ± 0.0
1.294AsnAsp: 1.294 ± 0.0
4.529AsnGlu: 4.529 ± 0.0
0.971AsnPhe: 0.971 ± 0.0
2.912AsnGly: 2.912 ± 0.0
0.324AsnHis: 0.324 ± 0.0
2.265AsnIle: 2.265 ± 0.0
1.618AsnLys: 1.618 ± 0.0
3.882AsnLeu: 3.882 ± 0.0
1.941AsnMet: 1.941 ± 0.0
1.294AsnAsn: 1.294 ± 0.0
3.882AsnPro: 3.882 ± 0.0
2.588AsnGln: 2.588 ± 0.0
1.941AsnArg: 1.941 ± 0.0
3.559AsnSer: 3.559 ± 0.0
1.618AsnThr: 1.618 ± 0.0
2.912AsnVal: 2.912 ± 0.0
0.324AsnTrp: 0.324 ± 0.0
1.294AsnTyr: 1.294 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.235ProAla: 3.235 ± 0.0
0.0ProCys: 0.0 ± 0.0
2.912ProAsp: 2.912 ± 0.0
4.529ProGlu: 4.529 ± 0.0
2.912ProPhe: 2.912 ± 0.0
3.559ProGly: 3.559 ± 0.0
2.265ProHis: 2.265 ± 0.0
3.882ProIle: 3.882 ± 0.0
1.618ProLys: 1.618 ± 0.0
5.176ProLeu: 5.176 ± 0.0
1.294ProMet: 1.294 ± 0.0
0.971ProAsn: 0.971 ± 0.0
3.559ProPro: 3.559 ± 0.0
2.588ProGln: 2.588 ± 0.0
3.559ProArg: 3.559 ± 0.0
4.853ProSer: 4.853 ± 0.0
4.206ProThr: 4.206 ± 0.0
5.823ProVal: 5.823 ± 0.0
0.647ProTrp: 0.647 ± 0.0
2.265ProTyr: 2.265 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
0.647GlnAla: 0.647 ± 0.0
0.647GlnCys: 0.647 ± 0.0
1.618GlnAsp: 1.618 ± 0.0
0.971GlnGlu: 0.971 ± 0.0
0.647GlnPhe: 0.647 ± 0.0
0.971GlnGly: 0.971 ± 0.0
0.971GlnHis: 0.971 ± 0.0
2.912GlnIle: 2.912 ± 0.0
2.265GlnLys: 2.265 ± 0.0
1.941GlnLeu: 1.941 ± 0.0
0.0GlnMet: 0.0 ± 0.0
1.294GlnAsn: 1.294 ± 0.0
1.618GlnPro: 1.618 ± 0.0
0.647GlnGln: 0.647 ± 0.0
2.588GlnArg: 2.588 ± 0.0
3.235GlnSer: 3.235 ± 0.0
1.618GlnThr: 1.618 ± 0.0
2.912GlnVal: 2.912 ± 0.0
0.0GlnTrp: 0.0 ± 0.0
0.647GlnTyr: 0.647 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.882ArgAla: 3.882 ± 0.0
0.971ArgCys: 0.971 ± 0.0
1.618ArgAsp: 1.618 ± 0.0
1.941ArgGlu: 1.941 ± 0.0
2.588ArgPhe: 2.588 ± 0.0
5.5ArgGly: 5.5 ± 0.0
1.294ArgHis: 1.294 ± 0.0
4.206ArgIle: 4.206 ± 0.0
2.912ArgLys: 2.912 ± 0.0
5.823ArgLeu: 5.823 ± 0.0
2.912ArgMet: 2.912 ± 0.0
3.559ArgAsn: 3.559 ± 0.0
2.265ArgPro: 2.265 ± 0.0
2.265ArgGln: 2.265 ± 0.0
3.882ArgArg: 3.882 ± 0.0
5.176ArgSer: 5.176 ± 0.0
3.559ArgThr: 3.559 ± 0.0
6.147ArgVal: 6.147 ± 0.0
0.647ArgTrp: 0.647 ± 0.0
0.647ArgTyr: 0.647 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
4.853SerAla: 4.853 ± 0.0
2.265SerCys: 2.265 ± 0.0
3.559SerAsp: 3.559 ± 0.0
4.206SerGlu: 4.206 ± 0.0
1.941SerPhe: 1.941 ± 0.0
5.176SerGly: 5.176 ± 0.0
0.324SerHis: 0.324 ± 0.0
5.176SerIle: 5.176 ± 0.0
3.882SerLys: 3.882 ± 0.0
4.853SerLeu: 4.853 ± 0.0
1.941SerMet: 1.941 ± 0.0
2.912SerAsn: 2.912 ± 0.0
5.5SerPro: 5.5 ± 0.0
2.912SerGln: 2.912 ± 0.0
4.529SerArg: 4.529 ± 0.0
4.529SerSer: 4.529 ± 0.0
8.088SerThr: 8.088 ± 0.0
5.823SerVal: 5.823 ± 0.0
0.324SerTrp: 0.324 ± 0.0
2.265SerTyr: 2.265 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
5.823ThrAla: 5.823 ± 0.0
1.294ThrCys: 1.294 ± 0.0
2.912ThrAsp: 2.912 ± 0.0
4.529ThrGlu: 4.529 ± 0.0
3.882ThrPhe: 3.882 ± 0.0
3.882ThrGly: 3.882 ± 0.0
2.265ThrHis: 2.265 ± 0.0
3.559ThrIle: 3.559 ± 0.0
1.941ThrLys: 1.941 ± 0.0
5.176ThrLeu: 5.176 ± 0.0
1.294ThrMet: 1.294 ± 0.0
1.941ThrAsn: 1.941 ± 0.0
4.529ThrPro: 4.529 ± 0.0
1.618ThrGln: 1.618 ± 0.0
6.147ThrArg: 6.147 ± 0.0
6.794ThrSer: 6.794 ± 0.0
8.412ThrThr: 8.412 ± 0.0
8.088ThrVal: 8.088 ± 0.0
1.294ThrTrp: 1.294 ± 0.0
3.882ThrTyr: 3.882 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
4.853ValAla: 4.853 ± 0.0
0.971ValCys: 0.971 ± 0.0
4.206ValAsp: 4.206 ± 0.0
6.147ValGlu: 6.147 ± 0.0
3.235ValPhe: 3.235 ± 0.0
5.823ValGly: 5.823 ± 0.0
1.294ValHis: 1.294 ± 0.0
4.206ValIle: 4.206 ± 0.0
2.912ValLys: 2.912 ± 0.0
6.147ValLeu: 6.147 ± 0.0
1.618ValMet: 1.618 ± 0.0
3.559ValAsn: 3.559 ± 0.0
5.5ValPro: 5.5 ± 0.0
1.618ValGln: 1.618 ± 0.0
5.823ValArg: 5.823 ± 0.0
6.147ValSer: 6.147 ± 0.0
4.853ValThr: 4.853 ± 0.0
8.088ValVal: 8.088 ± 0.0
0.324ValTrp: 0.324 ± 0.0
3.559ValTyr: 3.559 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.647TrpAla: 0.647 ± 0.0
0.324TrpCys: 0.324 ± 0.0
1.618TrpAsp: 1.618 ± 0.0
1.294TrpGlu: 1.294 ± 0.0
0.324TrpPhe: 0.324 ± 0.0
0.324TrpGly: 0.324 ± 0.0
0.647TrpHis: 0.647 ± 0.0
0.324TrpIle: 0.324 ± 0.0
0.324TrpLys: 0.324 ± 0.0
1.294TrpLeu: 1.294 ± 0.0
0.324TrpMet: 0.324 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.324TrpGln: 0.324 ± 0.0
0.647TrpArg: 0.647 ± 0.0
0.971TrpSer: 0.971 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.647TrpVal: 0.647 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.647TrpTyr: 0.647 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.912TyrAla: 2.912 ± 0.0
0.971TyrCys: 0.971 ± 0.0
1.941TyrAsp: 1.941 ± 0.0
2.265TyrGlu: 2.265 ± 0.0
1.618TyrPhe: 1.618 ± 0.0
1.941TyrGly: 1.941 ± 0.0
0.647TyrHis: 0.647 ± 0.0
0.971TyrIle: 0.971 ± 0.0
1.618TyrLys: 1.618 ± 0.0
1.294TyrLeu: 1.294 ± 0.0
2.265TyrMet: 2.265 ± 0.0
2.265TyrAsn: 2.265 ± 0.0
0.971TyrPro: 0.971 ± 0.0
0.971TyrGln: 0.971 ± 0.0
1.618TyrArg: 1.618 ± 0.0
2.588TyrSer: 2.588 ± 0.0
2.912TyrThr: 2.912 ± 0.0
2.265TyrVal: 2.265 ± 0.0
0.971TyrTrp: 0.971 ± 0.0
0.324TyrTyr: 0.324 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3092 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski