Amino acid dipepetide frequency for Falsigemmobacter faecalis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
18.901AlaAla: 18.901 ± 0.188
1.077AlaCys: 1.077 ± 0.032
6.714AlaAsp: 6.714 ± 0.085
9.009AlaGlu: 9.009 ± 0.116
4.325AlaPhe: 4.325 ± 0.067
12.164AlaGly: 12.164 ± 0.13
2.151AlaHis: 2.151 ± 0.049
5.494AlaIle: 5.494 ± 0.073
3.641AlaLys: 3.641 ± 0.065
15.721AlaLeu: 15.721 ± 0.12
3.698AlaMet: 3.698 ± 0.068
2.295AlaAsn: 2.295 ± 0.048
6.436AlaPro: 6.436 ± 0.111
4.555AlaGln: 4.555 ± 0.07
10.018AlaArg: 10.018 ± 0.094
5.7AlaSer: 5.7 ± 0.072
5.689AlaThr: 5.689 ± 0.076
8.596AlaVal: 8.596 ± 0.087
1.633AlaTrp: 1.633 ± 0.032
2.161AlaTyr: 2.161 ± 0.044
0.0AlaXaa: 0.0 ± 0.0
Cys
1.069CysAla: 1.069 ± 0.03
0.112CysCys: 0.112 ± 0.01
0.587CysAsp: 0.587 ± 0.023
0.434CysGlu: 0.434 ± 0.021
0.299CysPhe: 0.299 ± 0.017
0.906CysGly: 0.906 ± 0.03
0.278CysHis: 0.278 ± 0.017
0.361CysIle: 0.361 ± 0.015
0.168CysLys: 0.168 ± 0.012
0.903CysLeu: 0.903 ± 0.026
0.147CysMet: 0.147 ± 0.011
0.197CysAsn: 0.197 ± 0.014
0.534CysPro: 0.534 ± 0.021
0.242CysGln: 0.242 ± 0.014
0.621CysArg: 0.621 ± 0.024
0.454CysSer: 0.454 ± 0.02
0.435CysThr: 0.435 ± 0.02
0.524CysVal: 0.524 ± 0.024
0.108CysTrp: 0.108 ± 0.011
0.186CysTyr: 0.186 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
5.799AspAla: 5.799 ± 0.076
0.5AspCys: 0.5 ± 0.024
2.45AspAsp: 2.45 ± 0.063
3.103AspGlu: 3.103 ± 0.059
2.191AspPhe: 2.191 ± 0.043
4.603AspGly: 4.603 ± 0.09
1.151AspHis: 1.151 ± 0.036
2.528AspIle: 2.528 ± 0.064
1.291AspLys: 1.291 ± 0.036
7.27AspLeu: 7.27 ± 0.099
1.278AspMet: 1.278 ± 0.032
0.994AspAsn: 0.994 ± 0.03
3.621AspPro: 3.621 ± 0.055
1.837AspGln: 1.837 ± 0.034
3.967AspArg: 3.967 ± 0.066
2.086AspSer: 2.086 ± 0.044
2.183AspThr: 2.183 ± 0.051
3.598AspVal: 3.598 ± 0.067
1.039AspTrp: 1.039 ± 0.028
1.437AspTyr: 1.437 ± 0.034
0.0AspXaa: 0.0 ± 0.0
Glu
9.36GluAla: 9.36 ± 0.11
0.316GluCys: 0.316 ± 0.017
2.993GluAsp: 2.993 ± 0.046
3.567GluGlu: 3.567 ± 0.066
1.799GluPhe: 1.799 ± 0.042
5.665GluGly: 5.665 ± 0.096
1.007GluHis: 1.007 ± 0.029
3.56GluIle: 3.56 ± 0.053
2.047GluLys: 2.047 ± 0.043
5.182GluLeu: 5.182 ± 0.073
1.737GluMet: 1.737 ± 0.034
1.533GluAsn: 1.533 ± 0.036
2.55GluPro: 2.55 ± 0.052
1.765GluGln: 1.765 ± 0.042
4.325GluArg: 4.325 ± 0.067
2.211GluSer: 2.211 ± 0.041
3.547GluThr: 3.547 ± 0.052
4.513GluVal: 4.513 ± 0.057
0.658GluTrp: 0.658 ± 0.027
0.87GluTyr: 0.87 ± 0.028
0.0GluXaa: 0.0 ± 0.0
Phe
4.577PheAla: 4.577 ± 0.068
0.418PheCys: 0.418 ± 0.018
2.426PheAsp: 2.426 ± 0.047
2.051PheGlu: 2.051 ± 0.042
1.327PhePhe: 1.327 ± 0.033
3.696PheGly: 3.696 ± 0.058
0.727PheHis: 0.727 ± 0.027
1.538PheIle: 1.538 ± 0.042
0.82PheLys: 0.82 ± 0.026
3.457PheLeu: 3.457 ± 0.059
0.813PheMet: 0.813 ± 0.026
0.978PheAsn: 0.978 ± 0.028
1.526PhePro: 1.526 ± 0.04
1.022PheGln: 1.022 ± 0.032
2.331PheArg: 2.331 ± 0.043
2.269PheSer: 2.269 ± 0.045
2.124PheThr: 2.124 ± 0.042
2.413PheVal: 2.413 ± 0.055
0.562PheTrp: 0.562 ± 0.024
0.814PheTyr: 0.814 ± 0.027
0.0PheXaa: 0.0 ± 0.0
Gly
10.649GlyAla: 10.649 ± 0.121
0.822GlyCys: 0.822 ± 0.026
4.373GlyAsp: 4.373 ± 0.096
5.013GlyGlu: 5.013 ± 0.084
3.75GlyPhe: 3.75 ± 0.058
8.033GlyGly: 8.033 ± 0.158
1.94GlyHis: 1.94 ± 0.041
4.382GlyIle: 4.382 ± 0.062
2.895GlyLys: 2.895 ± 0.059
10.248GlyLeu: 10.248 ± 0.121
2.584GlyMet: 2.584 ± 0.052
2.015GlyAsn: 2.015 ± 0.056
3.846GlyPro: 3.846 ± 0.059
3.303GlyGln: 3.303 ± 0.057
6.572GlyArg: 6.572 ± 0.077
4.69GlySer: 4.69 ± 0.079
4.44GlyThr: 4.44 ± 0.06
6.306GlyVal: 6.306 ± 0.08
1.461GlyTrp: 1.461 ± 0.038
2.216GlyTyr: 2.216 ± 0.049
0.0GlyXaa: 0.0 ± 0.0
His
2.097HisAla: 2.097 ± 0.047
0.219HisCys: 0.219 ± 0.014
1.097HisAsp: 1.097 ± 0.029
1.024HisGlu: 1.024 ± 0.03
0.785HisPhe: 0.785 ± 0.023
1.717HisGly: 1.717 ± 0.039
0.541HisHis: 0.541 ± 0.026
0.959HisIle: 0.959 ± 0.032
0.449HisLys: 0.449 ± 0.02
2.256HisLeu: 2.256 ± 0.049
0.503HisMet: 0.503 ± 0.021
0.444HisAsn: 0.444 ± 0.021
1.366HisPro: 1.366 ± 0.036
0.655HisGln: 0.655 ± 0.021
1.328HisArg: 1.328 ± 0.036
0.991HisSer: 0.991 ± 0.028
0.735HisThr: 0.735 ± 0.024
1.234HisVal: 1.234 ± 0.036
0.317HisTrp: 0.317 ± 0.019
0.523HisTyr: 0.523 ± 0.023
0.0HisXaa: 0.0 ± 0.0
Ile
6.838IleAla: 6.838 ± 0.083
0.644IleCys: 0.644 ± 0.023
2.894IleAsp: 2.894 ± 0.055
3.098IleGlu: 3.098 ± 0.053
1.819IlePhe: 1.819 ± 0.04
4.694IleGly: 4.694 ± 0.071
0.856IleHis: 0.856 ± 0.03
2.051IleIle: 2.051 ± 0.048
1.09IleLys: 1.09 ± 0.033
4.929IleLeu: 4.929 ± 0.077
1.007IleMet: 1.007 ± 0.036
1.224IleAsn: 1.224 ± 0.03
2.29IlePro: 2.29 ± 0.047
1.018IleGln: 1.018 ± 0.031
3.693IleArg: 3.693 ± 0.056
3.127IleSer: 3.127 ± 0.052
2.98IleThr: 2.98 ± 0.05
3.067IleVal: 3.067 ± 0.058
0.759IleTrp: 0.759 ± 0.025
1.07IleTyr: 1.07 ± 0.029
0.0IleXaa: 0.0 ± 0.0
Lys
3.951LysAla: 3.951 ± 0.063
0.153LysCys: 0.153 ± 0.011
1.613LysAsp: 1.613 ± 0.04
1.411LysGlu: 1.411 ± 0.038
0.903LysPhe: 0.903 ± 0.032
2.674LysGly: 2.674 ± 0.051
0.496LysHis: 0.496 ± 0.022
1.627LysIle: 1.627 ± 0.038
1.056LysLys: 1.056 ± 0.034
2.933LysLeu: 2.933 ± 0.05
0.804LysMet: 0.804 ± 0.029
0.73LysAsn: 0.73 ± 0.028
1.66LysPro: 1.66 ± 0.041
0.73LysGln: 0.73 ± 0.029
1.911LysArg: 1.911 ± 0.049
1.695LysSer: 1.695 ± 0.041
1.645LysThr: 1.645 ± 0.038
2.146LysVal: 2.146 ± 0.048
0.331LysTrp: 0.331 ± 0.019
0.566LysTyr: 0.566 ± 0.022
0.0LysXaa: 0.0 ± 0.0
Leu
14.334LeuAla: 14.334 ± 0.132
1.083LeuCys: 1.083 ± 0.032
5.204LeuAsp: 5.204 ± 0.081
5.556LeuGlu: 5.556 ± 0.068
3.302LeuPhe: 3.302 ± 0.06
8.351LeuGly: 8.351 ± 0.106
1.986LeuHis: 1.986 ± 0.046
5.584LeuIle: 5.584 ± 0.073
3.451LeuLys: 3.451 ± 0.06
10.396LeuLeu: 10.396 ± 0.135
2.937LeuMet: 2.937 ± 0.055
2.836LeuAsn: 2.836 ± 0.05
6.653LeuPro: 6.653 ± 0.092
3.517LeuGln: 3.517 ± 0.052
8.731LeuArg: 8.731 ± 0.098
8.234LeuSer: 8.234 ± 0.097
6.598LeuThr: 6.598 ± 0.07
6.861LeuVal: 6.861 ± 0.076
1.403LeuTrp: 1.403 ± 0.039
2.002LeuTyr: 2.002 ± 0.053
0.0LeuXaa: 0.0 ± 0.0
Met
3.564MetAla: 3.564 ± 0.064
0.162MetCys: 0.162 ± 0.011
1.134MetAsp: 1.134 ± 0.031
1.381MetGlu: 1.381 ± 0.033
0.72MetPhe: 0.72 ± 0.027
2.133MetGly: 2.133 ± 0.049
0.396MetHis: 0.396 ± 0.019
1.551MetIle: 1.551 ± 0.044
1.029MetLys: 1.029 ± 0.03
2.554MetLeu: 2.554 ± 0.05
0.75MetMet: 0.75 ± 0.028
0.729MetAsn: 0.729 ± 0.022
1.388MetPro: 1.388 ± 0.038
0.904MetGln: 0.904 ± 0.026
1.876MetArg: 1.876 ± 0.039
1.821MetSer: 1.821 ± 0.043
1.972MetThr: 1.972 ± 0.041
1.763MetVal: 1.763 ± 0.043
0.2MetTrp: 0.2 ± 0.011
0.296MetTyr: 0.296 ± 0.014
0.0MetXaa: 0.0 ± 0.0
Asn
2.81AsnAla: 2.81 ± 0.051
0.208AsnCys: 0.208 ± 0.013
1.223AsnAsp: 1.223 ± 0.047
1.014AsnGlu: 1.014 ± 0.03
0.935AsnPhe: 0.935 ± 0.028
2.149AsnGly: 2.149 ± 0.049
0.48AsnHis: 0.48 ± 0.019
1.284AsnIle: 1.284 ± 0.036
0.555AsnLys: 0.555 ± 0.021
2.455AsnLeu: 2.455 ± 0.041
0.574AsnMet: 0.574 ± 0.022
0.553AsnAsn: 0.553 ± 0.023
1.802AsnPro: 1.802 ± 0.041
0.648AsnGln: 0.648 ± 0.023
1.765AsnArg: 1.765 ± 0.037
1.134AsnSer: 1.134 ± 0.031
1.194AsnThr: 1.194 ± 0.03
1.543AsnVal: 1.543 ± 0.039
0.342AsnTrp: 0.342 ± 0.018
0.524AsnTyr: 0.524 ± 0.027
0.0AsnXaa: 0.0 ± 0.0
Pro
7.008ProAla: 7.008 ± 0.11
0.354ProCys: 0.354 ± 0.019
3.531ProAsp: 3.531 ± 0.062
4.766ProGlu: 4.766 ± 0.081
1.915ProPhe: 1.915 ± 0.04
5.442ProGly: 5.442 ± 0.082
1.047ProHis: 1.047 ± 0.029
1.798ProIle: 1.798 ± 0.04
1.603ProLys: 1.603 ± 0.038
5.33ProLeu: 5.33 ± 0.074
1.241ProMet: 1.241 ± 0.033
1.025ProAsn: 1.025 ± 0.03
2.81ProPro: 2.81 ± 0.068
1.985ProGln: 1.985 ± 0.045
3.194ProArg: 3.194 ± 0.056
2.415ProSer: 2.415 ± 0.047
1.973ProThr: 1.973 ± 0.041
4.552ProVal: 4.552 ± 0.067
0.76ProTrp: 0.76 ± 0.028
0.926ProTyr: 0.926 ± 0.028
0.0ProXaa: 0.0 ± 0.0
Gln
4.285GlnAla: 4.285 ± 0.056
0.192GlnCys: 0.192 ± 0.013
1.648GlnAsp: 1.648 ± 0.04
1.522GlnGlu: 1.522 ± 0.036
1.025GlnPhe: 1.025 ± 0.028
2.908GlnGly: 2.908 ± 0.06
0.621GlnHis: 0.621 ± 0.021
2.226GlnIle: 2.226 ± 0.044
1.084GlnLys: 1.084 ± 0.032
2.949GlnLeu: 2.949 ± 0.049
1.017GlnMet: 1.017 ± 0.03
0.872GlnAsn: 0.872 ± 0.031
1.792GlnPro: 1.792 ± 0.044
1.108GlnGln: 1.108 ± 0.041
2.37GlnArg: 2.37 ± 0.048
2.016GlnSer: 2.016 ± 0.045
1.654GlnThr: 1.654 ± 0.041
2.368GlnVal: 2.368 ± 0.048
0.339GlnTrp: 0.339 ± 0.018
0.534GlnTyr: 0.534 ± 0.021
0.0GlnXaa: 0.0 ± 0.0
Arg
9.21ArgAla: 9.21 ± 0.11
0.502ArgCys: 0.502 ± 0.019
4.11ArgAsp: 4.11 ± 0.057
4.305ArgGlu: 4.305 ± 0.072
2.766ArgPhe: 2.766 ± 0.048
5.365ArgGly: 5.365 ± 0.076
1.631ArgHis: 1.631 ± 0.04
3.913ArgIle: 3.913 ± 0.055
2.069ArgLys: 2.069 ± 0.05
8.677ArgLeu: 8.677 ± 0.1
2.057ArgMet: 2.057 ± 0.043
1.768ArgAsn: 1.768 ± 0.037
3.816ArgPro: 3.816 ± 0.066
2.564ArgGln: 2.564 ± 0.054
5.855ArgArg: 5.855 ± 0.101
3.919ArgSer: 3.919 ± 0.064
2.774ArgThr: 2.774 ± 0.048
4.929ArgVal: 4.929 ± 0.067
0.96ArgTrp: 0.96 ± 0.031
1.564ArgTyr: 1.564 ± 0.04
0.0ArgXaa: 0.0 ± 0.0
Ser
6.556SerAla: 6.556 ± 0.092
0.454SerCys: 0.454 ± 0.02
3.173SerAsp: 3.173 ± 0.055
3.118SerGlu: 3.118 ± 0.053
2.356SerPhe: 2.356 ± 0.047
6.015SerGly: 6.015 ± 0.081
1.094SerHis: 1.094 ± 0.029
2.217SerIle: 2.217 ± 0.05
1.354SerLys: 1.354 ± 0.038
5.87SerLeu: 5.87 ± 0.077
1.273SerMet: 1.273 ± 0.033
1.244SerAsn: 1.244 ± 0.033
2.899SerPro: 2.899 ± 0.048
1.754SerGln: 1.754 ± 0.052
3.859SerArg: 3.859 ± 0.063
2.62SerSer: 2.62 ± 0.044
2.409SerThr: 2.409 ± 0.056
3.907SerVal: 3.907 ± 0.066
0.805SerTrp: 0.805 ± 0.026
1.357SerTyr: 1.357 ± 0.033
0.0SerXaa: 0.0 ± 0.0
Thr
6.605ThrAla: 6.605 ± 0.088
0.395ThrCys: 0.395 ± 0.019
2.581ThrAsp: 2.581 ± 0.047
3.083ThrGlu: 3.083 ± 0.054
1.756ThrPhe: 1.756 ± 0.042
5.419ThrGly: 5.419 ± 0.087
0.95ThrHis: 0.95 ± 0.031
2.354ThrIle: 2.354 ± 0.052
1.204ThrLys: 1.204 ± 0.034
6.042ThrLeu: 6.042 ± 0.072
1.046ThrMet: 1.046 ± 0.029
1.028ThrAsn: 1.028 ± 0.032
3.458ThrPro: 3.458 ± 0.054
1.304ThrGln: 1.304 ± 0.033
3.689ThrArg: 3.689 ± 0.053
2.699ThrSer: 2.699 ± 0.046
2.579ThrThr: 2.579 ± 0.057
3.541ThrVal: 3.541 ± 0.057
0.746ThrTrp: 0.746 ± 0.027
0.929ThrTyr: 0.929 ± 0.028
0.0ThrXaa: 0.0 ± 0.0
Val
8.584ValAla: 8.584 ± 0.097
0.608ValCys: 0.608 ± 0.023
3.188ValAsp: 3.188 ± 0.063
3.906ValGlu: 3.906 ± 0.066
2.655ValPhe: 2.655 ± 0.052
4.554ValGly: 4.554 ± 0.07
1.128ValHis: 1.128 ± 0.03
4.195ValIle: 4.195 ± 0.07
2.27ValLys: 2.27 ± 0.052
7.911ValLeu: 7.911 ± 0.09
2.055ValMet: 2.055 ± 0.039
1.858ValAsn: 1.858 ± 0.044
3.435ValPro: 3.435 ± 0.058
2.203ValGln: 2.203 ± 0.042
4.018ValArg: 4.018 ± 0.058
4.396ValSer: 4.396 ± 0.071
4.758ValThr: 4.758 ± 0.075
5.356ValVal: 5.356 ± 0.077
0.958ValTrp: 0.958 ± 0.027
1.289ValTyr: 1.289 ± 0.032
0.0ValXaa: 0.0 ± 0.0
Trp
1.448TrpAla: 1.448 ± 0.038
0.144TrpCys: 0.144 ± 0.01
0.656TrpAsp: 0.656 ± 0.023
0.628TrpGlu: 0.628 ± 0.024
0.524TrpPhe: 0.524 ± 0.021
1.054TrpGly: 1.054 ± 0.032
0.302TrpHis: 0.302 ± 0.018
0.672TrpIle: 0.672 ± 0.026
0.429TrpLys: 0.429 ± 0.018
1.798TrpLeu: 1.798 ± 0.043
0.387TrpMet: 0.387 ± 0.019
0.365TrpAsn: 0.365 ± 0.017
0.794TrpPro: 0.794 ± 0.025
0.749TrpGln: 0.749 ± 0.03
1.159TrpArg: 1.159 ± 0.03
0.79TrpSer: 0.79 ± 0.026
0.703TrpThr: 0.703 ± 0.026
0.832TrpVal: 0.832 ± 0.026
0.21TrpTrp: 0.21 ± 0.013
0.267TrpTyr: 0.267 ± 0.015
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.332TyrAla: 2.332 ± 0.045
0.202TyrCys: 0.202 ± 0.013
1.329TyrAsp: 1.329 ± 0.035
1.214TyrGlu: 1.214 ± 0.036
0.737TyrPhe: 0.737 ± 0.027
1.996TyrGly: 1.996 ± 0.044
0.459TyrHis: 0.459 ± 0.02
0.856TyrIle: 0.856 ± 0.026
0.527TyrLys: 0.527 ± 0.027
2.137TyrLeu: 2.137 ± 0.051
0.416TyrMet: 0.416 ± 0.019
0.504TyrAsn: 0.504 ± 0.019
1.001TyrPro: 1.001 ± 0.029
0.668TyrGln: 0.668 ± 0.024
1.473TyrArg: 1.473 ± 0.036
1.065TyrSer: 1.065 ± 0.034
1.015TyrThr: 1.015 ± 0.03
1.276TyrVal: 1.276 ± 0.037
0.322TyrTrp: 0.322 ± 0.016
0.48TyrTyr: 0.48 ± 0.022
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3827 proteins (1200599 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski