Amino acid dipepetide frequency for Aliifodinibius halophilus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.996AlaAla: 4.996 ± 0.088	0.515AlaCys: 0.515 ± 0.022	4.272AlaAsp: 4.272 ± 0.072	4.815AlaGlu: 4.815 ± 0.073	3.008AlaPhe: 3.008 ± 0.055	4.977AlaGly: 4.977 ± 0.077	1.233AlaHis: 1.233 ± 0.034	4.99AlaIle: 4.99 ± 0.071	3.899AlaLys: 3.899 ± 0.057	6.361AlaLeu: 6.361 ± 0.098	1.686AlaMet: 1.686 ± 0.045	2.991AlaAsn: 2.991 ± 0.053	2.323AlaPro: 2.323 ± 0.047	2.811AlaGln: 2.811 ± 0.049	2.805AlaArg: 2.805 ± 0.061	4.313AlaSer: 4.313 ± 0.069	3.787AlaThr: 3.787 ± 0.069	4.555AlaVal: 4.555 ± 0.071	0.767AlaTrp: 0.767 ± 0.028	2.311AlaTyr: 2.311 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.419CysAla: 0.419 ± 0.02	0.096CysCys: 0.096 ± 0.01	0.391CysAsp: 0.391 ± 0.018	0.402CysGlu: 0.402 ± 0.019	0.321CysPhe: 0.321 ± 0.017	0.604CysGly: 0.604 ± 0.026	0.181CysHis: 0.181 ± 0.013	0.442CysIle: 0.442 ± 0.018	0.351CysLys: 0.351 ± 0.016	0.524CysLeu: 0.524 ± 0.02	0.138CysMet: 0.138 ± 0.011	0.328CysAsn: 0.328 ± 0.017	0.314CysPro: 0.314 ± 0.019	0.212CysGln: 0.212 ± 0.014	0.321CysArg: 0.321 ± 0.016	0.532CysSer: 0.532 ± 0.021	0.373CysThr: 0.373 ± 0.017	0.38CysVal: 0.38 ± 0.02	0.089CysTrp: 0.089 ± 0.008	0.257CysTyr: 0.257 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.662AspAla: 3.662 ± 0.051	0.356AspCys: 0.356 ± 0.019	3.602AspAsp: 3.602 ± 0.05	4.818AspGlu: 4.818 ± 0.07	2.936AspPhe: 2.936 ± 0.051	4.46AspGly: 4.46 ± 0.129	1.354AspHis: 1.354 ± 0.035	4.675AspIle: 4.675 ± 0.059	3.696AspLys: 3.696 ± 0.065	5.63AspLeu: 5.63 ± 0.076	1.331AspMet: 1.331 ± 0.036	2.819AspAsn: 2.819 ± 0.061	2.628AspPro: 2.628 ± 0.049	2.437AspGln: 2.437 ± 0.053	2.888AspArg: 2.888 ± 0.047	3.89AspSer: 3.89 ± 0.076	3.33AspThr: 3.33 ± 0.056	3.605AspVal: 3.605 ± 0.059	0.86AspTrp: 0.86 ± 0.029	2.406AspTyr: 2.406 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	5.046GluAla: 5.046 ± 0.08	0.357GluCys: 0.357 ± 0.019	4.231GluAsp: 4.231 ± 0.069	6.943GluGlu: 6.943 ± 0.12	2.756GluPhe: 2.756 ± 0.051	4.597GluGly: 4.597 ± 0.067	1.555GluHis: 1.555 ± 0.036	5.075GluIle: 5.075 ± 0.069	5.136GluLys: 5.136 ± 0.082	7.136GluLeu: 7.136 ± 0.09	1.86GluMet: 1.86 ± 0.041	3.583GluAsn: 3.583 ± 0.063	2.172GluPro: 2.172 ± 0.046	3.651GluGln: 3.651 ± 0.066	3.366GluArg: 3.366 ± 0.055	3.972GluSer: 3.972 ± 0.057	3.622GluThr: 3.622 ± 0.055	5.024GluVal: 5.024 ± 0.074	0.879GluTrp: 0.879 ± 0.032	2.562GluTyr: 2.562 ± 0.048	0.0GluXaa: 0.0 ± 0.0
Phe	2.774PheAla: 2.774 ± 0.054	0.384PheCys: 0.384 ± 0.02	3.026PheAsp: 3.026 ± 0.049	3.371PheGlu: 3.371 ± 0.06	2.169PhePhe: 2.169 ± 0.051	3.283PheGly: 3.283 ± 0.052	0.807PheHis: 0.807 ± 0.025	3.018PheIle: 3.018 ± 0.064	2.505PheLys: 2.505 ± 0.051	3.998PheLeu: 3.998 ± 0.065	0.989PheMet: 0.989 ± 0.028	2.357PheAsn: 2.357 ± 0.052	1.517PhePro: 1.517 ± 0.039	1.372PheGln: 1.372 ± 0.031	1.848PheArg: 1.848 ± 0.049	3.72PheSer: 3.72 ± 0.064	2.679PheThr: 2.679 ± 0.052	2.717PheVal: 2.717 ± 0.052	0.692PheTrp: 0.692 ± 0.029	1.704PheTyr: 1.704 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	4.606GlyAla: 4.606 ± 0.069	0.61GlyCys: 0.61 ± 0.023	4.075GlyAsp: 4.075 ± 0.096	4.43GlyGlu: 4.43 ± 0.068	3.275GlyPhe: 3.275 ± 0.053	5.136GlyGly: 5.136 ± 0.096	1.311GlyHis: 1.311 ± 0.037	5.339GlyIle: 5.339 ± 0.065	4.103GlyLys: 4.103 ± 0.06	6.201GlyLeu: 6.201 ± 0.087	1.844GlyMet: 1.844 ± 0.049	3.402GlyAsn: 3.402 ± 0.074	1.952GlyPro: 1.952 ± 0.046	2.45GlyGln: 2.45 ± 0.048	2.872GlyArg: 2.872 ± 0.052	4.794GlySer: 4.794 ± 0.083	4.378GlyThr: 4.378 ± 0.092	4.31GlyVal: 4.31 ± 0.076	1.051GlyTrp: 1.051 ± 0.032	2.974GlyTyr: 2.974 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	1.211HisAla: 1.211 ± 0.033	0.169HisCys: 0.169 ± 0.013	1.096HisAsp: 1.096 ± 0.03	1.225HisGlu: 1.225 ± 0.026	1.071HisPhe: 1.071 ± 0.031	1.285HisGly: 1.285 ± 0.036	0.616HisHis: 0.616 ± 0.025	1.473HisIle: 1.473 ± 0.034	1.15HisLys: 1.15 ± 0.033	1.883HisLeu: 1.883 ± 0.044	0.378HisMet: 0.378 ± 0.018	0.967HisAsn: 0.967 ± 0.031	1.191HisPro: 1.191 ± 0.034	0.857HisGln: 0.857 ± 0.026	1.025HisArg: 1.025 ± 0.029	1.265HisSer: 1.265 ± 0.032	1.041HisThr: 1.041 ± 0.031	1.03HisVal: 1.03 ± 0.03	0.304HisTrp: 0.304 ± 0.016	0.834HisTyr: 0.834 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	5.094IleAla: 5.094 ± 0.076	0.562IleCys: 0.562 ± 0.025	4.68IleAsp: 4.68 ± 0.068	5.142IleGlu: 5.142 ± 0.071	2.906IlePhe: 2.906 ± 0.056	4.817IleGly: 4.817 ± 0.07	1.387IleHis: 1.387 ± 0.033	4.586IleIle: 4.586 ± 0.08	3.999IleLys: 3.999 ± 0.058	5.821IleLeu: 5.821 ± 0.096	1.292IleMet: 1.292 ± 0.034	3.541IleAsn: 3.541 ± 0.06	3.119IlePro: 3.119 ± 0.053	2.557IleGln: 2.557 ± 0.05	3.123IleArg: 3.123 ± 0.056	5.454IleSer: 5.454 ± 0.07	4.575IleThr: 4.575 ± 0.088	4.021IleVal: 4.021 ± 0.061	0.716IleTrp: 0.716 ± 0.027	2.385IleTyr: 2.385 ± 0.051	0.001IleXaa: 0.001 ± 0.001
Lys	4.463LysAla: 4.463 ± 0.066	0.239LysCys: 0.239 ± 0.017	3.48LysAsp: 3.48 ± 0.063	5.681LysGlu: 5.681 ± 0.09	1.888LysPhe: 1.888 ± 0.04	3.874LysGly: 3.874 ± 0.069	1.212LysHis: 1.212 ± 0.032	3.907LysIle: 3.907 ± 0.06	5.449LysLys: 5.449 ± 0.101	5.51LysLeu: 5.51 ± 0.071	1.616LysMet: 1.616 ± 0.038	3.2LysAsn: 3.2 ± 0.053	2.115LysPro: 2.115 ± 0.04	2.708LysGln: 2.708 ± 0.054	3.116LysArg: 3.116 ± 0.051	3.724LysSer: 3.724 ± 0.057	3.324LysThr: 3.324 ± 0.058	4.088LysVal: 4.088 ± 0.067	0.689LysTrp: 0.689 ± 0.025	2.188LysTyr: 2.188 ± 0.042	0.0LysXaa: 0.0 ± 0.0
Leu	6.517LeuAla: 6.517 ± 0.087	0.625LeuCys: 0.625 ± 0.021	5.557LeuAsp: 5.557 ± 0.079	6.266LeuGlu: 6.266 ± 0.077	4.354LeuPhe: 4.354 ± 0.083	6.101LeuGly: 6.101 ± 0.081	1.744LeuHis: 1.744 ± 0.041	6.124LeuIle: 6.124 ± 0.086	5.826LeuLys: 5.826 ± 0.078	8.815LeuLeu: 8.815 ± 0.115	2.08LeuMet: 2.08 ± 0.05	4.549LeuAsn: 4.549 ± 0.065	3.836LeuPro: 3.836 ± 0.059	3.786LeuGln: 3.786 ± 0.062	4.009LeuArg: 4.009 ± 0.065	6.944LeuSer: 6.944 ± 0.086	5.214LeuThr: 5.214 ± 0.083	5.497LeuVal: 5.497 ± 0.072	0.997LeuTrp: 0.997 ± 0.031	3.083LeuTyr: 3.083 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	1.823MetAla: 1.823 ± 0.042	0.092MetCys: 0.092 ± 0.009	1.484MetAsp: 1.484 ± 0.037	1.604MetGlu: 1.604 ± 0.036	0.867MetPhe: 0.867 ± 0.03	1.726MetGly: 1.726 ± 0.038	0.42MetHis: 0.42 ± 0.018	1.499MetIle: 1.499 ± 0.041	1.651MetLys: 1.651 ± 0.043	2.111MetLeu: 2.111 ± 0.053	0.667MetMet: 0.667 ± 0.032	1.23MetAsn: 1.23 ± 0.029	1.02MetPro: 1.02 ± 0.032	0.918MetGln: 0.918 ± 0.027	1.042MetArg: 1.042 ± 0.034	1.56MetSer: 1.56 ± 0.037	1.116MetThr: 1.116 ± 0.031	1.539MetVal: 1.539 ± 0.038	0.186MetTrp: 0.186 ± 0.013	0.584MetTyr: 0.584 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.112AsnAla: 3.112 ± 0.051	0.333AsnCys: 0.333 ± 0.018	2.676AsnAsp: 2.676 ± 0.062	3.217AsnGlu: 3.217 ± 0.061	2.16AsnPhe: 2.16 ± 0.043	3.568AsnGly: 3.568 ± 0.065	1.026AsnHis: 1.026 ± 0.031	3.885AsnIle: 3.885 ± 0.059	3.108AsnLys: 3.108 ± 0.058	4.11AsnLeu: 4.11 ± 0.057	1.207AsnMet: 1.207 ± 0.035	2.824AsnAsn: 2.824 ± 0.059	2.603AsnPro: 2.603 ± 0.05	1.85AsnGln: 1.85 ± 0.046	2.39AsnArg: 2.39 ± 0.049	3.199AsnSer: 3.199 ± 0.074	2.843AsnThr: 2.843 ± 0.066	2.811AsnVal: 2.811 ± 0.048	0.683AsnTrp: 0.683 ± 0.024	2.057AsnTyr: 2.057 ± 0.042	0.0AsnXaa: 0.0 ± 0.0
Pro	2.503ProAla: 2.503 ± 0.048	0.227ProCys: 0.227 ± 0.014	2.984ProAsp: 2.984 ± 0.059	3.367ProGlu: 3.367 ± 0.059	1.918ProPhe: 1.918 ± 0.041	2.618ProGly: 2.618 ± 0.05	0.816ProHis: 0.816 ± 0.028	2.539ProIle: 2.539 ± 0.045	2.269ProLys: 2.269 ± 0.044	3.234ProLeu: 3.234 ± 0.056	0.781ProMet: 0.781 ± 0.029	1.974ProAsn: 1.974 ± 0.046	1.324ProPro: 1.324 ± 0.037	1.553ProGln: 1.553 ± 0.038	1.323ProArg: 1.323 ± 0.035	2.582ProSer: 2.582 ± 0.05	2.122ProThr: 2.122 ± 0.045	2.713ProVal: 2.713 ± 0.053	0.419ProTrp: 0.419 ± 0.02	1.394ProTyr: 1.394 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	2.703GlnAla: 2.703 ± 0.048	0.183GlnCys: 0.183 ± 0.011	2.117GlnAsp: 2.117 ± 0.046	2.963GlnGlu: 2.963 ± 0.051	1.705GlnPhe: 1.705 ± 0.04	2.117GlnGly: 2.117 ± 0.044	0.864GlnHis: 0.864 ± 0.028	2.496GlnIle: 2.496 ± 0.05	3.097GlnLys: 3.097 ± 0.057	4.199GlnLeu: 4.199 ± 0.063	0.997GlnMet: 0.997 ± 0.03	2.041GlnAsn: 2.041 ± 0.043	1.507GlnPro: 1.507 ± 0.032	2.632GlnGln: 2.632 ± 0.064	1.822GlnArg: 1.822 ± 0.047	2.592GlnSer: 2.592 ± 0.053	2.152GlnThr: 2.152 ± 0.048	2.286GlnVal: 2.286 ± 0.042	0.552GlnTrp: 0.552 ± 0.025	1.443GlnTyr: 1.443 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	2.662ArgAla: 2.662 ± 0.049	0.269ArgCys: 0.269 ± 0.018	2.493ArgAsp: 2.493 ± 0.047	3.237ArgGlu: 3.237 ± 0.057	2.237ArgPhe: 2.237 ± 0.047	2.582ArgGly: 2.582 ± 0.047	0.865ArgHis: 0.865 ± 0.032	3.303ArgIle: 3.303 ± 0.061	3.041ArgLys: 3.041 ± 0.055	4.135ArgLeu: 4.135 ± 0.063	1.1ArgMet: 1.1 ± 0.031	2.281ArgAsn: 2.281 ± 0.047	1.489ArgPro: 1.489 ± 0.035	1.757ArgGln: 1.757 ± 0.044	2.098ArgArg: 2.098 ± 0.054	2.932ArgSer: 2.932 ± 0.06	2.247ArgThr: 2.247 ± 0.044	2.527ArgVal: 2.527 ± 0.045	0.625ArgTrp: 0.625 ± 0.021	2.02ArgTyr: 2.02 ± 0.043	0.001ArgXaa: 0.001 ± 0.001
Ser	4.321SerAla: 4.321 ± 0.075	0.515SerCys: 0.515 ± 0.023	4.219SerAsp: 4.219 ± 0.067	4.511SerGlu: 4.511 ± 0.064	3.471SerPhe: 3.471 ± 0.062	5.251SerGly: 5.251 ± 0.078	1.202SerHis: 1.202 ± 0.034	4.716SerIle: 4.716 ± 0.059	3.828SerLys: 3.828 ± 0.061	6.353SerLeu: 6.353 ± 0.087	1.513SerMet: 1.513 ± 0.039	3.465SerAsn: 3.465 ± 0.068	2.501SerPro: 2.501 ± 0.057	2.411SerGln: 2.411 ± 0.049	2.785SerArg: 2.785 ± 0.059	5.292SerSer: 5.292 ± 0.089	4.013SerThr: 4.013 ± 0.071	4.344SerVal: 4.344 ± 0.062	0.938SerTrp: 0.938 ± 0.032	2.698SerTyr: 2.698 ± 0.063	0.0SerXaa: 0.0 ± 0.0
Thr	4.097ThrAla: 4.097 ± 0.072	0.289ThrCys: 0.289 ± 0.016	3.75ThrAsp: 3.75 ± 0.063	3.668ThrGlu: 3.668 ± 0.06	2.842ThrPhe: 2.842 ± 0.06	4.409ThrGly: 4.409 ± 0.073	1.096ThrHis: 1.096 ± 0.032	4.268ThrIle: 4.268 ± 0.07	2.948ThrLys: 2.948 ± 0.051	5.389ThrLeu: 5.389 ± 0.072	1.152ThrMet: 1.152 ± 0.035	2.602ThrAsn: 2.602 ± 0.049	2.449ThrPro: 2.449 ± 0.047	1.985ThrGln: 1.985 ± 0.041	1.756ThrArg: 1.756 ± 0.038	3.598ThrSer: 3.598 ± 0.07	3.358ThrThr: 3.358 ± 0.075	4.195ThrVal: 4.195 ± 0.077	0.506ThrTrp: 0.506 ± 0.021	2.128ThrTyr: 2.128 ± 0.053	0.0ThrXaa: 0.0 ± 0.0
Val	4.361ValAla: 4.361 ± 0.063	0.447ValCys: 0.447 ± 0.02	4.159ValAsp: 4.159 ± 0.067	4.532ValGlu: 4.532 ± 0.072	2.708ValPhe: 2.708 ± 0.046	4.354ValGly: 4.354 ± 0.069	1.212ValHis: 1.212 ± 0.036	4.29ValIle: 4.29 ± 0.062	3.496ValLys: 3.496 ± 0.058	5.707ValLeu: 5.707 ± 0.077	1.471ValMet: 1.471 ± 0.036	2.979ValAsn: 2.979 ± 0.057	2.598ValPro: 2.598 ± 0.05	2.232ValGln: 2.232 ± 0.041	2.724ValArg: 2.724 ± 0.054	4.541ValSer: 4.541 ± 0.068	3.76ValThr: 3.76 ± 0.069	4.15ValVal: 4.15 ± 0.074	0.682ValTrp: 0.682 ± 0.025	2.119ValTyr: 2.119 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.815TrpAla: 0.815 ± 0.026	0.086TrpCys: 0.086 ± 0.009	0.749TrpAsp: 0.749 ± 0.028	0.785TrpGlu: 0.785 ± 0.026	0.554TrpPhe: 0.554 ± 0.025	0.854TrpGly: 0.854 ± 0.03	0.319TrpHis: 0.319 ± 0.016	0.871TrpIle: 0.871 ± 0.03	0.789TrpLys: 0.789 ± 0.027	1.184TrpLeu: 1.184 ± 0.041	0.349TrpMet: 0.349 ± 0.015	0.61TrpAsn: 0.61 ± 0.025	0.37TrpPro: 0.37 ± 0.016	0.612TrpGln: 0.612 ± 0.023	0.534TrpArg: 0.534 ± 0.021	0.804TrpSer: 0.804 ± 0.028	0.605TrpThr: 0.605 ± 0.024	0.781TrpVal: 0.781 ± 0.025	0.215TrpTrp: 0.215 ± 0.013	0.472TrpTyr: 0.472 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.232TyrAla: 2.232 ± 0.045	0.319TyrCys: 0.319 ± 0.016	2.343TyrAsp: 2.343 ± 0.045	2.545TyrGlu: 2.545 ± 0.053	1.781TyrPhe: 1.781 ± 0.037	2.499TyrGly: 2.499 ± 0.045	0.849TyrHis: 0.849 ± 0.027	2.283TyrIle: 2.283 ± 0.048	2.134TyrLys: 2.134 ± 0.046	3.621TyrLeu: 3.621 ± 0.054	0.687TyrMet: 0.687 ± 0.021	1.92TyrAsn: 1.92 ± 0.044	1.633TyrPro: 1.633 ± 0.039	1.678TyrGln: 1.678 ± 0.046	2.053TyrArg: 2.053 ± 0.052	2.639TyrSer: 2.639 ± 0.048	1.943TyrThr: 1.943 ± 0.052	1.949TyrVal: 1.949 ± 0.039	0.511TyrTrp: 0.511 ± 0.022	1.56TyrTyr: 1.56 ± 0.039	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.001XaaThr: 0.001 ± 0.001	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3590 proteins (1192668 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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