Amino acid dipepetide frequency for Consotaella salsifontis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.725AlaAla: 17.725 ± 0.174	1.019AlaCys: 1.019 ± 0.03	6.919AlaAsp: 6.919 ± 0.081	8.741AlaGlu: 8.741 ± 0.09	4.694AlaPhe: 4.694 ± 0.062	10.742AlaGly: 10.742 ± 0.107	2.187AlaHis: 2.187 ± 0.046	6.583AlaIle: 6.583 ± 0.069	4.109AlaLys: 4.109 ± 0.064	13.744AlaLeu: 13.744 ± 0.117	3.727AlaMet: 3.727 ± 0.05	2.757AlaAsn: 2.757 ± 0.056	5.795AlaPro: 5.795 ± 0.092	3.318AlaGln: 3.318 ± 0.06	8.925AlaArg: 8.925 ± 0.1	7.128AlaSer: 7.128 ± 0.079	5.934AlaThr: 5.934 ± 0.07	9.261AlaVal: 9.261 ± 0.107	1.347AlaTrp: 1.347 ± 0.036	2.454AlaTyr: 2.454 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.891CysAla: 0.891 ± 0.027	0.125CysCys: 0.125 ± 0.011	0.511CysAsp: 0.511 ± 0.021	0.469CysGlu: 0.469 ± 0.022	0.336CysPhe: 0.336 ± 0.015	0.953CysGly: 0.953 ± 0.029	0.247CysHis: 0.247 ± 0.013	0.371CysIle: 0.371 ± 0.019	0.164CysLys: 0.164 ± 0.012	0.806CysLeu: 0.806 ± 0.026	0.144CysMet: 0.144 ± 0.011	0.17CysAsn: 0.17 ± 0.01	0.455CysPro: 0.455 ± 0.022	0.27CysGln: 0.27 ± 0.014	0.67CysArg: 0.67 ± 0.021	0.461CysSer: 0.461 ± 0.017	0.342CysThr: 0.342 ± 0.015	0.582CysVal: 0.582 ± 0.024	0.11CysTrp: 0.11 ± 0.009	0.183CysTyr: 0.183 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	6.805AspAla: 6.805 ± 0.068	0.485AspCys: 0.485 ± 0.019	3.231AspAsp: 3.231 ± 0.065	3.902AspGlu: 3.902 ± 0.062	2.198AspPhe: 2.198 ± 0.041	5.253AspGly: 5.253 ± 0.079	1.351AspHis: 1.351 ± 0.038	2.987AspIle: 2.987 ± 0.046	1.702AspLys: 1.702 ± 0.04	6.1AspLeu: 6.1 ± 0.079	1.296AspMet: 1.296 ± 0.032	1.216AspAsn: 1.216 ± 0.037	3.403AspPro: 3.403 ± 0.058	1.697AspGln: 1.697 ± 0.036	4.426AspArg: 4.426 ± 0.069	2.166AspSer: 2.166 ± 0.042	2.352AspThr: 2.352 ± 0.045	4.093AspVal: 4.093 ± 0.06	0.911AspTrp: 0.911 ± 0.032	1.409AspTyr: 1.409 ± 0.028	0.0AspXaa: 0.0 ± 0.0
Glu	8.855GluAla: 8.855 ± 0.09	0.388GluCys: 0.388 ± 0.018	3.123GluAsp: 3.123 ± 0.049	4.17GluGlu: 4.17 ± 0.073	1.781GluPhe: 1.781 ± 0.041	4.717GluGly: 4.717 ± 0.057	1.251GluHis: 1.251 ± 0.029	3.663GluIle: 3.663 ± 0.063	2.611GluLys: 2.611 ± 0.048	5.302GluLeu: 5.302 ± 0.066	1.679GluMet: 1.679 ± 0.035	1.566GluAsn: 1.566 ± 0.036	3.015GluPro: 3.015 ± 0.056	1.923GluGln: 1.923 ± 0.044	5.7GluArg: 5.7 ± 0.097	2.577GluSer: 2.577 ± 0.046	3.869GluThr: 3.869 ± 0.053	4.115GluVal: 4.115 ± 0.063	0.738GluTrp: 0.738 ± 0.025	0.947GluTyr: 0.947 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	4.692PheAla: 4.692 ± 0.065	0.399PheCys: 0.399 ± 0.017	2.722PheAsp: 2.722 ± 0.041	2.159PheGlu: 2.159 ± 0.046	1.572PhePhe: 1.572 ± 0.039	3.671PheGly: 3.671 ± 0.058	0.737PheHis: 0.737 ± 0.022	1.797PheIle: 1.797 ± 0.039	0.944PheLys: 0.944 ± 0.028	3.623PheLeu: 3.623 ± 0.059	0.829PheMet: 0.829 ± 0.024	0.977PheAsn: 0.977 ± 0.03	1.568PhePro: 1.568 ± 0.033	1.051PheGln: 1.051 ± 0.029	2.27PheArg: 2.27 ± 0.039	2.528PheSer: 2.528 ± 0.039	1.83PheThr: 1.83 ± 0.038	2.945PheVal: 2.945 ± 0.049	0.536PheTrp: 0.536 ± 0.023	0.863PheTyr: 0.863 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	9.715GlyAla: 9.715 ± 0.102	0.88GlyCys: 0.88 ± 0.027	4.309GlyAsp: 4.309 ± 0.061	5.552GlyGlu: 5.552 ± 0.084	3.521GlyPhe: 3.521 ± 0.053	7.26GlyGly: 7.26 ± 0.103	1.852GlyHis: 1.852 ± 0.041	4.631GlyIle: 4.631 ± 0.059	3.096GlyLys: 3.096 ± 0.056	8.727GlyLeu: 8.727 ± 0.087	2.162GlyMet: 2.162 ± 0.045	2.016GlyAsn: 2.016 ± 0.052	3.339GlyPro: 3.339 ± 0.048	2.621GlyGln: 2.621 ± 0.045	6.675GlyArg: 6.675 ± 0.077	4.787GlySer: 4.787 ± 0.068	4.311GlyThr: 4.311 ± 0.072	6.145GlyVal: 6.145 ± 0.075	1.306GlyTrp: 1.306 ± 0.037	2.135GlyTyr: 2.135 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.106HisAla: 2.106 ± 0.043	0.22HisCys: 0.22 ± 0.013	1.163HisAsp: 1.163 ± 0.033	1.105HisGlu: 1.105 ± 0.031	0.861HisPhe: 0.861 ± 0.026	1.843HisGly: 1.843 ± 0.035	0.586HisHis: 0.586 ± 0.029	0.846HisIle: 0.846 ± 0.025	0.438HisLys: 0.438 ± 0.017	2.075HisLeu: 2.075 ± 0.04	0.441HisMet: 0.441 ± 0.016	0.385HisAsn: 0.385 ± 0.018	1.309HisPro: 1.309 ± 0.035	0.574HisGln: 0.574 ± 0.022	1.538HisArg: 1.538 ± 0.033	0.97HisSer: 0.97 ± 0.033	0.748HisThr: 0.748 ± 0.025	1.507HisVal: 1.507 ± 0.032	0.325HisTrp: 0.325 ± 0.017	0.549HisTyr: 0.549 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	7.478IleAla: 7.478 ± 0.081	0.454IleCys: 0.454 ± 0.021	3.727IleAsp: 3.727 ± 0.055	3.793IleGlu: 3.793 ± 0.059	1.766IlePhe: 1.766 ± 0.05	5.053IleGly: 5.053 ± 0.066	0.916IleHis: 0.916 ± 0.026	2.285IleIle: 2.285 ± 0.045	1.352IleLys: 1.352 ± 0.032	4.759IleLeu: 4.759 ± 0.066	0.993IleMet: 0.993 ± 0.027	1.266IleAsn: 1.266 ± 0.034	2.252IlePro: 2.252 ± 0.044	1.208IleGln: 1.208 ± 0.03	3.203IleArg: 3.203 ± 0.046	2.93IleSer: 2.93 ± 0.049	2.495IleThr: 2.495 ± 0.046	4.465IleVal: 4.465 ± 0.059	0.517IleTrp: 0.517 ± 0.02	1.086IleTyr: 1.086 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	4.425LysAla: 4.425 ± 0.07	0.15LysCys: 0.15 ± 0.012	1.792LysAsp: 1.792 ± 0.036	1.795LysGlu: 1.795 ± 0.039	0.777LysPhe: 0.777 ± 0.026	2.668LysGly: 2.668 ± 0.048	0.501LysHis: 0.501 ± 0.021	1.685LysIle: 1.685 ± 0.035	1.247LysLys: 1.247 ± 0.035	2.935LysLeu: 2.935 ± 0.048	0.777LysMet: 0.777 ± 0.025	0.852LysAsn: 0.852 ± 0.027	1.893LysPro: 1.893 ± 0.047	0.89LysGln: 0.89 ± 0.028	2.514LysArg: 2.514 ± 0.049	1.849LysSer: 1.849 ± 0.038	1.97LysThr: 1.97 ± 0.039	2.523LysVal: 2.523 ± 0.048	0.319LysTrp: 0.319 ± 0.015	0.519LysTyr: 0.519 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	13.935LeuAla: 13.935 ± 0.13	0.87LeuCys: 0.87 ± 0.028	6.182LeuAsp: 6.182 ± 0.078	5.338LeuGlu: 5.338 ± 0.068	3.896LeuPhe: 3.896 ± 0.053	8.269LeuGly: 8.269 ± 0.096	1.698LeuHis: 1.698 ± 0.037	5.059LeuIle: 5.059 ± 0.07	3.745LeuLys: 3.745 ± 0.057	9.391LeuLeu: 9.391 ± 0.098	2.296LeuMet: 2.296 ± 0.045	2.252LeuAsn: 2.252 ± 0.046	5.338LeuPro: 5.338 ± 0.07	2.547LeuGln: 2.547 ± 0.048	6.452LeuArg: 6.452 ± 0.083	7.15LeuSer: 7.15 ± 0.073	5.469LeuThr: 5.469 ± 0.067	7.933LeuVal: 7.933 ± 0.082	1.056LeuTrp: 1.056 ± 0.031	1.957LeuTyr: 1.957 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	3.234MetAla: 3.234 ± 0.052	0.13MetCys: 0.13 ± 0.01	1.173MetAsp: 1.173 ± 0.031	1.269MetGlu: 1.269 ± 0.033	0.648MetPhe: 0.648 ± 0.023	1.778MetGly: 1.778 ± 0.042	0.374MetHis: 0.374 ± 0.015	1.44MetIle: 1.44 ± 0.031	1.022MetLys: 1.022 ± 0.026	2.318MetLeu: 2.318 ± 0.043	0.718MetMet: 0.718 ± 0.023	0.771MetAsn: 0.771 ± 0.023	1.472MetPro: 1.472 ± 0.034	0.694MetGln: 0.694 ± 0.026	1.866MetArg: 1.866 ± 0.042	1.672MetSer: 1.672 ± 0.038	1.856MetThr: 1.856 ± 0.036	1.756MetVal: 1.756 ± 0.033	0.189MetTrp: 0.189 ± 0.013	0.26MetTyr: 0.26 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.963AsnAla: 2.963 ± 0.049	0.221AsnCys: 0.221 ± 0.014	1.373AsnAsp: 1.373 ± 0.036	1.323AsnGlu: 1.323 ± 0.031	0.901AsnPhe: 0.901 ± 0.027	2.201AsnGly: 2.201 ± 0.037	0.45AsnHis: 0.45 ± 0.017	1.194AsnIle: 1.194 ± 0.037	0.576AsnLys: 0.576 ± 0.02	2.419AsnLeu: 2.419 ± 0.042	0.527AsnMet: 0.527 ± 0.019	0.597AsnAsn: 0.597 ± 0.024	1.627AsnPro: 1.627 ± 0.036	0.721AsnGln: 0.721 ± 0.024	1.734AsnArg: 1.734 ± 0.042	1.14AsnSer: 1.14 ± 0.032	1.093AsnThr: 1.093 ± 0.034	1.793AsnVal: 1.793 ± 0.037	0.356AsnTrp: 0.356 ± 0.015	0.614AsnTyr: 0.614 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	6.387ProAla: 6.387 ± 0.096	0.316ProCys: 0.316 ± 0.016	3.48ProAsp: 3.48 ± 0.055	3.707ProGlu: 3.707 ± 0.069	2.081ProPhe: 2.081 ± 0.039	4.143ProGly: 4.143 ± 0.064	1.006ProHis: 1.006 ± 0.029	2.44ProIle: 2.44 ± 0.041	1.605ProLys: 1.605 ± 0.037	4.862ProLeu: 4.862 ± 0.072	1.151ProMet: 1.151 ± 0.032	1.21ProAsn: 1.21 ± 0.03	2.475ProPro: 2.475 ± 0.06	1.508ProGln: 1.508 ± 0.039	3.042ProArg: 3.042 ± 0.049	3.184ProSer: 3.184 ± 0.054	2.555ProThr: 2.555 ± 0.042	4.056ProVal: 4.056 ± 0.064	0.623ProTrp: 0.623 ± 0.021	1.152ProTyr: 1.152 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	3.785GlnAla: 3.785 ± 0.056	0.161GlnCys: 0.161 ± 0.01	1.355GlnAsp: 1.355 ± 0.036	1.569GlnGlu: 1.569 ± 0.035	0.901GlnPhe: 0.901 ± 0.026	2.153GlnGly: 2.153 ± 0.043	0.514GlnHis: 0.514 ± 0.019	1.719GlnIle: 1.719 ± 0.035	1.095GlnLys: 1.095 ± 0.032	2.559GlnLeu: 2.559 ± 0.049	0.858GlnMet: 0.858 ± 0.029	0.796GlnAsn: 0.796 ± 0.023	1.669GlnPro: 1.669 ± 0.043	1.079GlnGln: 1.079 ± 0.035	2.456GlnArg: 2.456 ± 0.045	1.759GlnSer: 1.759 ± 0.038	1.664GlnThr: 1.664 ± 0.039	2.022GlnVal: 2.022 ± 0.037	0.329GlnTrp: 0.329 ± 0.015	0.5GlnTyr: 0.5 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	8.024ArgAla: 8.024 ± 0.094	0.556ArgCys: 0.556 ± 0.022	3.973ArgAsp: 3.973 ± 0.061	4.468ArgGlu: 4.468 ± 0.068	3.179ArgPhe: 3.179 ± 0.048	4.912ArgGly: 4.912 ± 0.069	1.817ArgHis: 1.817 ± 0.041	4.061ArgIle: 4.061 ± 0.06	2.201ArgLys: 2.201 ± 0.04	8.537ArgLeu: 8.537 ± 0.099	1.914ArgMet: 1.914 ± 0.037	1.709ArgAsn: 1.709 ± 0.034	3.783ArgPro: 3.783 ± 0.061	2.884ArgGln: 2.884 ± 0.056	6.566ArgArg: 6.566 ± 0.089	4.126ArgSer: 4.126 ± 0.068	3.319ArgThr: 3.319 ± 0.051	4.666ArgVal: 4.666 ± 0.065	0.927ArgTrp: 0.927 ± 0.031	1.624ArgTyr: 1.624 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	6.874SerAla: 6.874 ± 0.087	0.477SerCys: 0.477 ± 0.018	3.054SerAsp: 3.054 ± 0.053	3.194SerGlu: 3.194 ± 0.05	2.353SerPhe: 2.353 ± 0.037	5.888SerGly: 5.888 ± 0.077	1.143SerHis: 1.143 ± 0.033	3.008SerIle: 3.008 ± 0.045	1.5SerLys: 1.5 ± 0.036	5.932SerLeu: 5.932 ± 0.062	1.331SerMet: 1.331 ± 0.03	1.331SerAsn: 1.331 ± 0.03	3.04SerPro: 3.04 ± 0.049	1.721SerGln: 1.721 ± 0.038	4.09SerArg: 4.09 ± 0.057	3.411SerSer: 3.411 ± 0.062	2.733SerThr: 2.733 ± 0.055	4.289SerVal: 4.289 ± 0.059	0.768SerTrp: 0.768 ± 0.024	1.222SerTyr: 1.222 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	6.179ThrAla: 6.179 ± 0.081	0.39ThrCys: 0.39 ± 0.019	2.635ThrAsp: 2.635 ± 0.043	2.717ThrGlu: 2.717 ± 0.043	2.005ThrPhe: 2.005 ± 0.04	4.853ThrGly: 4.853 ± 0.065	0.898ThrHis: 0.898 ± 0.025	2.954ThrIle: 2.954 ± 0.049	1.389ThrLys: 1.389 ± 0.039	5.603ThrLeu: 5.603 ± 0.056	1.188ThrMet: 1.188 ± 0.032	1.246ThrAsn: 1.246 ± 0.034	3.02ThrPro: 3.02 ± 0.052	1.258ThrGln: 1.258 ± 0.038	3.191ThrArg: 3.191 ± 0.046	2.868ThrSer: 2.868 ± 0.052	2.727ThrThr: 2.727 ± 0.048	4.392ThrVal: 4.392 ± 0.069	0.572ThrTrp: 0.572 ± 0.02	1.14ThrTyr: 1.14 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	9.563ValAla: 9.563 ± 0.092	0.659ValCys: 0.659 ± 0.022	4.277ValAsp: 4.277 ± 0.061	4.975ValGlu: 4.975 ± 0.067	2.883ValPhe: 2.883 ± 0.052	5.824ValGly: 5.824 ± 0.071	1.343ValHis: 1.343 ± 0.033	3.83ValIle: 3.83 ± 0.067	2.343ValLys: 2.343 ± 0.041	7.489ValLeu: 7.489 ± 0.088	1.904ValMet: 1.904 ± 0.04	1.809ValAsn: 1.809 ± 0.039	3.846ValPro: 3.846 ± 0.061	1.772ValGln: 1.772 ± 0.038	5.066ValArg: 5.066 ± 0.069	4.638ValSer: 4.638 ± 0.07	4.301ValThr: 4.301 ± 0.063	6.321ValVal: 6.321 ± 0.073	0.811ValTrp: 0.811 ± 0.025	1.443ValTyr: 1.443 ± 0.032	0.0ValXaa: 0.0 ± 0.0
Trp	1.169TrpAla: 1.169 ± 0.029	0.125TrpCys: 0.125 ± 0.01	0.581TrpAsp: 0.581 ± 0.021	0.553TrpGlu: 0.553 ± 0.022	0.484TrpPhe: 0.484 ± 0.02	0.799TrpGly: 0.799 ± 0.027	0.273TrpHis: 0.273 ± 0.012	0.642TrpIle: 0.642 ± 0.023	0.402TrpLys: 0.402 ± 0.019	1.535TrpLeu: 1.535 ± 0.037	0.343TrpMet: 0.343 ± 0.017	0.359TrpAsn: 0.359 ± 0.015	0.656TrpPro: 0.656 ± 0.023	0.554TrpGln: 0.554 ± 0.022	1.11TrpArg: 1.11 ± 0.033	0.815TrpSer: 0.815 ± 0.027	0.715TrpThr: 0.715 ± 0.022	0.69TrpVal: 0.69 ± 0.02	0.222TrpTrp: 0.222 ± 0.015	0.244TrpTyr: 0.244 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.304TyrAla: 2.304 ± 0.041	0.234TyrCys: 0.234 ± 0.015	1.404TyrAsp: 1.404 ± 0.032	1.192TyrGlu: 1.192 ± 0.031	0.875TyrPhe: 0.875 ± 0.029	2.058TyrGly: 2.058 ± 0.04	0.444TyrHis: 0.444 ± 0.019	0.804TyrIle: 0.804 ± 0.025	0.542TyrLys: 0.542 ± 0.021	2.118TyrLeu: 2.118 ± 0.039	0.363TyrMet: 0.363 ± 0.014	0.537TyrAsn: 0.537 ± 0.022	1.026TyrPro: 1.026 ± 0.027	0.656TyrGln: 0.656 ± 0.021	1.753TyrArg: 1.753 ± 0.035	1.199TyrSer: 1.199 ± 0.033	0.94TyrThr: 0.94 ± 0.03	1.543TyrVal: 1.543 ± 0.033	0.309TyrTrp: 0.309 ± 0.016	0.505TyrTyr: 0.505 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4266 proteins (1357347 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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