Amino acid dipepetide frequency for Desulfofustis glycolicus DSM 9705

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.195AlaAla: 11.195 ± 0.128	1.215AlaCys: 1.215 ± 0.036	5.573AlaAsp: 5.573 ± 0.071	6.109AlaGlu: 6.109 ± 0.071	3.329AlaPhe: 3.329 ± 0.049	8.328AlaGly: 8.328 ± 0.097	1.71AlaHis: 1.71 ± 0.041	5.776AlaIle: 5.776 ± 0.069	3.131AlaLys: 3.131 ± 0.047	9.727AlaLeu: 9.727 ± 0.094	2.499AlaMet: 2.499 ± 0.043	2.363AlaAsn: 2.363 ± 0.053	3.356AlaPro: 3.356 ± 0.056	2.781AlaGln: 2.781 ± 0.05	5.874AlaArg: 5.874 ± 0.072	4.48AlaSer: 4.48 ± 0.066	4.894AlaThr: 4.894 ± 0.059	7.281AlaVal: 7.281 ± 0.087	0.952AlaTrp: 0.952 ± 0.028	2.204AlaTyr: 2.204 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	1.166CysAla: 1.166 ± 0.033	0.316CysCys: 0.316 ± 0.016	0.637CysAsp: 0.637 ± 0.023	0.582CysGlu: 0.582 ± 0.023	0.555CysPhe: 0.555 ± 0.019	1.369CysGly: 1.369 ± 0.033	0.434CysHis: 0.434 ± 0.026	0.655CysIle: 0.655 ± 0.024	0.36CysLys: 0.36 ± 0.016	1.374CysLeu: 1.374 ± 0.034	0.258CysMet: 0.258 ± 0.014	0.354CysAsn: 0.354 ± 0.017	0.777CysPro: 0.777 ± 0.03	0.42CysGln: 0.42 ± 0.018	1.242CysArg: 1.242 ± 0.037	0.951CysSer: 0.951 ± 0.029	0.644CysThr: 0.644 ± 0.022	0.695CysVal: 0.695 ± 0.025	0.153CysTrp: 0.153 ± 0.011	0.4CysTyr: 0.4 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	4.163AspAla: 4.163 ± 0.059	0.7AspCys: 0.7 ± 0.024	3.376AspAsp: 3.376 ± 0.056	3.961AspGlu: 3.961 ± 0.059	2.438AspPhe: 2.438 ± 0.046	4.6AspGly: 4.6 ± 0.063	1.378AspHis: 1.378 ± 0.035	3.75AspIle: 3.75 ± 0.052	2.034AspLys: 2.034 ± 0.038	6.178AspLeu: 6.178 ± 0.073	1.212AspMet: 1.212 ± 0.025	1.788AspAsn: 1.788 ± 0.036	2.826AspPro: 2.826 ± 0.048	2.123AspGln: 2.123 ± 0.036	4.217AspArg: 4.217 ± 0.053	2.893AspSer: 2.893 ± 0.05	2.796AspThr: 2.796 ± 0.048	3.329AspVal: 3.329 ± 0.048	0.764AspTrp: 0.764 ± 0.024	1.993AspTyr: 1.993 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	5.606GluAla: 5.606 ± 0.072	0.53GluCys: 0.53 ± 0.022	2.902GluAsp: 2.902 ± 0.058	4.271GluGlu: 4.271 ± 0.068	1.968GluPhe: 1.968 ± 0.043	3.382GluGly: 3.382 ± 0.057	1.462GluHis: 1.462 ± 0.039	4.278GluIle: 4.278 ± 0.058	3.426GluLys: 3.426 ± 0.064	6.784GluLeu: 6.784 ± 0.088	1.724GluMet: 1.724 ± 0.038	2.017GluAsn: 2.017 ± 0.044	2.496GluPro: 2.496 ± 0.044	3.502GluGln: 3.502 ± 0.054	4.67GluArg: 4.67 ± 0.063	3.088GluSer: 3.088 ± 0.049	3.556GluThr: 3.556 ± 0.051	3.94GluVal: 3.94 ± 0.057	0.543GluTrp: 0.543 ± 0.022	1.411GluTyr: 1.411 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.679PheAla: 3.679 ± 0.053	0.675PheCys: 0.675 ± 0.022	2.488PheAsp: 2.488 ± 0.041	1.952PheGlu: 1.952 ± 0.038	2.157PhePhe: 2.157 ± 0.044	3.327PheGly: 3.327 ± 0.053	0.88PheHis: 0.88 ± 0.026	2.344PheIle: 2.344 ± 0.043	1.392PheLys: 1.392 ± 0.033	4.251PheLeu: 4.251 ± 0.068	0.902PheMet: 0.902 ± 0.026	1.428PheAsn: 1.428 ± 0.033	1.782PhePro: 1.782 ± 0.037	1.259PheGln: 1.259 ± 0.026	2.34PheArg: 2.34 ± 0.04	3.088PheSer: 3.088 ± 0.052	2.25PheThr: 2.25 ± 0.038	2.891PheVal: 2.891 ± 0.048	0.532PheTrp: 0.532 ± 0.021	1.271PheTyr: 1.271 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	6.565GlyAla: 6.565 ± 0.079	1.267GlyCys: 1.267 ± 0.034	4.146GlyAsp: 4.146 ± 0.061	4.463GlyGlu: 4.463 ± 0.054	3.231GlyPhe: 3.231 ± 0.05	6.166GlyGly: 6.166 ± 0.104	1.659GlyHis: 1.659 ± 0.035	5.22GlyIle: 5.22 ± 0.054	3.446GlyLys: 3.446 ± 0.05	7.888GlyLeu: 7.888 ± 0.08	2.132GlyMet: 2.132 ± 0.038	2.325GlyAsn: 2.325 ± 0.046	2.622GlyPro: 2.622 ± 0.038	2.606GlyGln: 2.606 ± 0.049	5.244GlyArg: 5.244 ± 0.065	4.925GlySer: 4.925 ± 0.067	4.393GlyThr: 4.393 ± 0.053	5.456GlyVal: 5.456 ± 0.072	1.054GlyTrp: 1.054 ± 0.028	2.648GlyTyr: 2.648 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	1.604HisAla: 1.604 ± 0.039	0.368HisCys: 0.368 ± 0.015	1.271HisAsp: 1.271 ± 0.029	1.18HisGlu: 1.18 ± 0.028	1.001HisPhe: 1.001 ± 0.026	1.866HisGly: 1.866 ± 0.039	0.755HisHis: 0.755 ± 0.025	1.172HisIle: 1.172 ± 0.029	0.632HisLys: 0.632 ± 0.021	2.559HisLeu: 2.559 ± 0.048	0.393HisMet: 0.393 ± 0.016	0.65HisAsn: 0.65 ± 0.021	1.327HisPro: 1.327 ± 0.032	0.923HisGln: 0.923 ± 0.02	1.732HisArg: 1.732 ± 0.036	1.165HisSer: 1.165 ± 0.028	0.918HisThr: 0.918 ± 0.028	1.217HisVal: 1.217 ± 0.032	0.284HisTrp: 0.284 ± 0.015	0.797HisTyr: 0.797 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.843IleAla: 5.843 ± 0.066	0.889IleCys: 0.889 ± 0.023	4.474IleAsp: 4.474 ± 0.06	4.244IleGlu: 4.244 ± 0.054	2.467IlePhe: 2.467 ± 0.044	5.512IleGly: 5.512 ± 0.073	1.219IleHis: 1.219 ± 0.029	3.993IleIle: 3.993 ± 0.056	2.666IleLys: 2.666 ± 0.047	5.595IleLeu: 5.595 ± 0.063	1.392IleMet: 1.392 ± 0.029	2.31IleAsn: 2.31 ± 0.044	2.75IlePro: 2.75 ± 0.041	1.561IleGln: 1.561 ± 0.037	3.686IleArg: 3.686 ± 0.044	4.087IleSer: 4.087 ± 0.056	3.693IleThr: 3.693 ± 0.048	4.659IleVal: 4.659 ± 0.065	0.55IleTrp: 0.55 ± 0.021	1.625IleTyr: 1.625 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	3.331LysAla: 3.331 ± 0.051	0.336LysCys: 0.336 ± 0.018	2.043LysAsp: 2.043 ± 0.045	2.73LysGlu: 2.73 ± 0.047	1.07LysPhe: 1.07 ± 0.031	2.644LysGly: 2.644 ± 0.043	0.816LysHis: 0.816 ± 0.026	2.708LysIle: 2.708 ± 0.049	2.637LysLys: 2.637 ± 0.056	3.483LysLeu: 3.483 ± 0.051	1.163LysMet: 1.163 ± 0.029	1.599LysAsn: 1.599 ± 0.034	1.79LysPro: 1.79 ± 0.038	1.783LysGln: 1.783 ± 0.035	2.735LysArg: 2.735 ± 0.046	2.092LysSer: 2.092 ± 0.042	2.595LysThr: 2.595 ± 0.048	2.519LysVal: 2.519 ± 0.041	0.405LysTrp: 0.405 ± 0.015	0.993LysTyr: 0.993 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	11.468LeuAla: 11.468 ± 0.121	1.377LeuCys: 1.377 ± 0.031	5.866LeuAsp: 5.866 ± 0.07	5.922LeuGlu: 5.922 ± 0.065	4.768LeuPhe: 4.768 ± 0.07	7.529LeuGly: 7.529 ± 0.095	2.227LeuHis: 2.227 ± 0.04	6.313LeuIle: 6.313 ± 0.071	4.037LeuLys: 4.037 ± 0.067	12.734LeuLeu: 12.734 ± 0.152	2.087LeuMet: 2.087 ± 0.04	2.967LeuAsn: 2.967 ± 0.05	5.591LeuPro: 5.591 ± 0.063	4.129LeuGln: 4.129 ± 0.059	6.254LeuArg: 6.254 ± 0.074	6.817LeuSer: 6.817 ± 0.079	5.8LeuThr: 5.8 ± 0.072	7.749LeuVal: 7.749 ± 0.096	0.959LeuTrp: 0.959 ± 0.027	2.582LeuTyr: 2.582 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	2.543MetAla: 2.543 ± 0.045	0.207MetCys: 0.207 ± 0.013	1.158MetAsp: 1.158 ± 0.025	1.423MetGlu: 1.423 ± 0.033	0.755MetPhe: 0.755 ± 0.023	1.534MetGly: 1.534 ± 0.035	0.432MetHis: 0.432 ± 0.018	1.637MetIle: 1.637 ± 0.036	1.396MetLys: 1.396 ± 0.033	2.387MetLeu: 2.387 ± 0.039	0.66MetMet: 0.66 ± 0.023	1.003MetAsn: 1.003 ± 0.027	1.086MetPro: 1.086 ± 0.029	0.838MetGln: 0.838 ± 0.024	1.314MetArg: 1.314 ± 0.033	1.443MetSer: 1.443 ± 0.032	1.581MetThr: 1.581 ± 0.034	1.851MetVal: 1.851 ± 0.039	0.16MetTrp: 0.16 ± 0.011	0.447MetTyr: 0.447 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.15AsnAla: 2.15 ± 0.038	0.432AsnCys: 0.432 ± 0.018	1.695AsnAsp: 1.695 ± 0.04	1.749AsnGlu: 1.749 ± 0.038	1.029AsnPhe: 1.029 ± 0.031	2.52AsnGly: 2.52 ± 0.051	0.747AsnHis: 0.747 ± 0.025	1.967AsnIle: 1.967 ± 0.042	1.231AsnLys: 1.231 ± 0.03	3.373AsnLeu: 3.373 ± 0.051	0.709AsnMet: 0.709 ± 0.024	1.129AsnAsn: 1.129 ± 0.028	1.733AsnPro: 1.733 ± 0.036	1.157AsnGln: 1.157 ± 0.026	2.372AsnArg: 2.372 ± 0.039	1.694AsnSer: 1.694 ± 0.033	1.501AsnThr: 1.501 ± 0.033	1.934AsnVal: 1.934 ± 0.035	0.418AsnTrp: 0.418 ± 0.017	0.97AsnTyr: 0.97 ± 0.029	0.0AsnXaa: 0.0 ± 0.0
Pro	4.65ProAla: 4.65 ± 0.063	0.485ProCys: 0.485 ± 0.017	3.132ProAsp: 3.132 ± 0.052	3.632ProGlu: 3.632 ± 0.051	1.963ProPhe: 1.963 ± 0.034	3.844ProGly: 3.844 ± 0.054	0.974ProHis: 0.974 ± 0.028	2.4ProIle: 2.4 ± 0.036	1.423ProLys: 1.423 ± 0.035	4.851ProLeu: 4.851 ± 0.067	0.96ProMet: 0.96 ± 0.025	1.112ProAsn: 1.112 ± 0.025	2.254ProPro: 2.254 ± 0.045	1.509ProGln: 1.509 ± 0.033	2.105ProArg: 2.105 ± 0.041	2.409ProSer: 2.409 ± 0.042	2.157ProThr: 2.157 ± 0.04	3.849ProVal: 3.849 ± 0.058	0.571ProTrp: 0.571 ± 0.02	1.262ProTyr: 1.262 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	3.935GlnAla: 3.935 ± 0.057	0.389GlnCys: 0.389 ± 0.018	1.759GlnAsp: 1.759 ± 0.034	2.389GlnGlu: 2.389 ± 0.041	1.214GlnPhe: 1.214 ± 0.028	2.4GlnGly: 2.4 ± 0.041	0.879GlnHis: 0.879 ± 0.024	2.321GlnIle: 2.321 ± 0.043	1.551GlnLys: 1.551 ± 0.037	3.844GlnLeu: 3.844 ± 0.051	0.897GlnMet: 0.897 ± 0.024	1.038GlnAsn: 1.038 ± 0.03	1.789GlnPro: 1.789 ± 0.036	2.13GlnGln: 2.13 ± 0.039	2.751GlnArg: 2.751 ± 0.049	1.993GlnSer: 1.993 ± 0.037	2.059GlnThr: 2.059 ± 0.039	2.786GlnVal: 2.786 ± 0.047	0.419GlnTrp: 0.419 ± 0.017	0.814GlnTyr: 0.814 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	4.907ArgAla: 4.907 ± 0.061	0.954ArgCys: 0.954 ± 0.027	3.518ArgAsp: 3.518 ± 0.046	4.319ArgGlu: 4.319 ± 0.066	3.078ArgPhe: 3.078 ± 0.045	3.813ArgGly: 3.813 ± 0.047	1.622ArgHis: 1.622 ± 0.039	4.299ArgIle: 4.299 ± 0.047	2.699ArgLys: 2.699 ± 0.047	7.759ArgLeu: 7.759 ± 0.084	1.588ArgMet: 1.588 ± 0.036	1.938ArgAsn: 1.938 ± 0.035	2.842ArgPro: 2.842 ± 0.048	3.452ArgGln: 3.452 ± 0.055	4.971ArgArg: 4.971 ± 0.069	3.909ArgSer: 3.909 ± 0.049	3.175ArgThr: 3.175 ± 0.047	4.104ArgVal: 4.104 ± 0.059	0.811ArgTrp: 0.811 ± 0.023	2.148ArgTyr: 2.148 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	4.846SerAla: 4.846 ± 0.065	0.901SerCys: 0.901 ± 0.027	2.961SerAsp: 2.961 ± 0.052	3.295SerGlu: 3.295 ± 0.051	2.873SerPhe: 2.873 ± 0.049	5.624SerGly: 5.624 ± 0.065	1.191SerHis: 1.191 ± 0.026	3.643SerIle: 3.643 ± 0.049	1.846SerLys: 1.846 ± 0.034	6.471SerLeu: 6.471 ± 0.077	1.47SerMet: 1.47 ± 0.031	1.479SerAsn: 1.479 ± 0.036	2.707SerPro: 2.707 ± 0.056	1.733SerGln: 1.733 ± 0.033	3.876SerArg: 3.876 ± 0.054	3.691SerSer: 3.691 ± 0.055	2.987SerThr: 2.987 ± 0.048	4.094SerVal: 4.094 ± 0.055	0.889SerTrp: 0.889 ± 0.027	1.842SerTyr: 1.842 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.528ThrAla: 5.528 ± 0.07	0.682ThrCys: 0.682 ± 0.024	3.01ThrAsp: 3.01 ± 0.058	2.984ThrGlu: 2.984 ± 0.048	2.016ThrPhe: 2.016 ± 0.037	5.101ThrGly: 5.101 ± 0.054	0.941ThrHis: 0.941 ± 0.023	4.157ThrIle: 4.157 ± 0.059	1.695ThrLys: 1.695 ± 0.037	5.514ThrLeu: 5.514 ± 0.068	1.407ThrMet: 1.407 ± 0.034	1.489ThrAsn: 1.489 ± 0.039	2.732ThrPro: 2.732 ± 0.048	1.207ThrGln: 1.207 ± 0.031	2.856ThrArg: 2.856 ± 0.043	3.006ThrSer: 3.006 ± 0.044	3.287ThrThr: 3.287 ± 0.047	4.591ThrVal: 4.591 ± 0.064	0.538ThrTrp: 0.538 ± 0.021	1.447ThrTyr: 1.447 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	6.806ValAla: 6.806 ± 0.074	1.016ValCys: 1.016 ± 0.028	4.293ValAsp: 4.293 ± 0.06	4.281ValGlu: 4.281 ± 0.059	3.166ValPhe: 3.166 ± 0.055	4.918ValGly: 4.918 ± 0.076	1.396ValHis: 1.396 ± 0.032	4.627ValIle: 4.627 ± 0.058	2.635ValLys: 2.635 ± 0.039	7.522ValLeu: 7.522 ± 0.082	1.698ValMet: 1.698 ± 0.038	2.237ValAsn: 2.237 ± 0.045	3.168ValPro: 3.168 ± 0.044	2.114ValGln: 2.114 ± 0.038	4.239ValArg: 4.239 ± 0.051	4.418ValSer: 4.418 ± 0.06	4.074ValThr: 4.074 ± 0.056	5.671ValVal: 5.671 ± 0.08	0.682ValTrp: 0.682 ± 0.021	1.853ValTyr: 1.853 ± 0.04	0.0ValXaa: 0.0 ± 0.0
Trp	0.798TrpAla: 0.798 ± 0.026	0.159TrpCys: 0.159 ± 0.011	0.523TrpAsp: 0.523 ± 0.021	0.568TrpGlu: 0.568 ± 0.024	0.53TrpPhe: 0.53 ± 0.019	0.714TrpGly: 0.714 ± 0.028	0.3TrpHis: 0.3 ± 0.014	0.58TrpIle: 0.58 ± 0.023	0.424TrpLys: 0.424 ± 0.018	1.5TrpLeu: 1.5 ± 0.042	0.253TrpMet: 0.253 ± 0.013	0.381TrpAsn: 0.381 ± 0.019	0.543TrpPro: 0.543 ± 0.022	0.778TrpGln: 0.778 ± 0.023	0.831TrpArg: 0.831 ± 0.028	0.667TrpSer: 0.667 ± 0.025	0.483TrpThr: 0.483 ± 0.019	0.64TrpVal: 0.64 ± 0.021	0.172TrpTrp: 0.172 ± 0.011	0.352TrpTyr: 0.352 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.992TyrAla: 1.992 ± 0.042	0.445TyrCys: 0.445 ± 0.018	1.692TyrAsp: 1.692 ± 0.039	1.504TyrGlu: 1.504 ± 0.033	1.277TyrPhe: 1.277 ± 0.029	2.266TyrGly: 2.266 ± 0.043	0.793TyrHis: 0.793 ± 0.021	1.376TyrIle: 1.376 ± 0.031	0.811TyrLys: 0.811 ± 0.027	3.384TyrLeu: 3.384 ± 0.059	0.453TyrMet: 0.453 ± 0.018	0.902TyrAsn: 0.902 ± 0.027	1.369TyrPro: 1.369 ± 0.034	1.354TyrGln: 1.354 ± 0.032	2.597TyrArg: 2.597 ± 0.047	1.602TyrSer: 1.602 ± 0.04	1.342TyrThr: 1.342 ± 0.037	1.558TyrVal: 1.558 ± 0.031	0.34TyrTrp: 0.34 ± 0.017	0.931TyrTyr: 0.931 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4455 proteins (1448063 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---